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Conserved domains on  [gi|1720422357|ref|XP_030098383|]
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ataxin-2-like protein isoform X12 [Mus musculus]

Protein Classification

SM-ATX and LsmAD domain-containing protein( domain architecture ID 13860551)

SM-ATX and LsmAD domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SM-ATX pfam14438
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
 35-108 3.04e-19

Ataxin 2 SM domain; This SM domain is found in Ataxin-2.


:

Pssm-ID: 464173  Cd Length: 78  Bit Score: 82.99  E-value: 3.04e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422357  35 MLHFLTAVVGSTCDVKVKNGTTYEGIFKTLS--SKFELAVDAVHRKASE--PAGGPRREDIVDTMVFKPSDVLLVHFR 108
Cdd:pfam14438   1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASleKDFGVVLKMARRIKKSngSGLNPVRGEIVDTMIFPAKDIVDIEAK 78
LsmAD pfam06741
LsmAD domain; This domain is found associated with Lsm domain.
 176-238 1.43e-17

LsmAD domain; This domain is found associated with Lsm domain.


:

Pssm-ID: 461998 [Multi-domain]  Cd Length: 65  Bit Score: 77.61  E-value: 1.43e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422357 176 YGVKTTYDSSLssYTVPLEKdNSEEFRQRELRAAQLAREIESSPQYRLRIAMEN-----DDGRTEEEK 238
Cdd:pfam06741   1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERgldvdDSGLDEEDK 65
PAT1 super family cl37801
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 663-882 9.78e-11

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


The actual alignment was detected with superfamily member pfam09770:

Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 65.83  E-value: 9.78e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 663 PPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSyiPYNPQQFPGQPAMMQPMA--------------HYPSQPVFAP 728
Cdd:pfam09770 107 PAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRT--GYEKYKEPEPIPDLQVDAslwgvapkkaaapaPAPQPAAQPA 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 729 MLQSNPRMLTS--------------------GSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATQL--HGHQPQ 786
Cdd:pfam09770 185 SLPAPSRKMMSleeveaamraqakkpaqqpaPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHpgQGHPVT 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 787 PATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPqssfPQPAavyaiHPHQQL 866
Cdd:pfam09770 265 ILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQ----PAPA-----HQAHRQ 335

                         250
                  ....*....|....*.
gi 1720422357 867 PHGFTNMAHVTQAHVQ 882
Cdd:pfam09770 336 QGSFGRQAPIITHPQQ 351
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 248-854 3.09e-08

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 58.03  E-value: 3.09e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  248 GRESPSLVSREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPgpgsearginggPSRMSPKAQRP 327
Cdd:PHA03247  2513 SRLAPAILPDEPVGEPVHPRMLTWIRGLEELASDDAGDPPPPLPPAAPPAAPDRSVP------------PPRPAPRPSEP 2580

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  328 LRGAKtlsspSNRPsgeaSVPPTSAVGRMY-----PPRSPKSAAPAPVSASCPEPPI--GSAVASSASIPVTSSVVDPGA 400
Cdd:PHA03247  2581 AVTSR-----ARRP----DAPPQSARPRAPvddrgDPRGPAPPSPLPPDTHAPDPPPpsPSPAANEPDPHPPPTVPPPER 2651

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  401 GSISPASPKLSLtptdvkelptkePSRnleAQELARIAGKVPGLQNEQKRfqleelrkfgaqfKLQPSSSPETGL-DPFP 479
Cdd:PHA03247  2652 PRDDPAPGRVSR------------PRR---ARRLGRAAQASSPPQRPRRR-------------AARPTVGSLTSLaDPPP 2703

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  480 srilkeeakgkekevdglltsdPMGSPVSSktesildkedkvPMAGVGGTEGPeqlPAPCPSQTGSPPVGLikgdekeeG 559
Cdd:PHA03247  2704 ----------------------PPPTPEPA------------PHALVSATPLP---PGPAAARQASPALPA--------A 2738

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  560 PVTEQVKKSTLNPNAKEFNPTKPLlsvnksTSTPTSPGPrthstPSIPVlTAGQSGLYSPQYISYIPQIHMGPAVQAPQM 639
Cdd:PHA03247  2739 PAPPAVPAGPATPGGPARPARPPT------TAGPPAPAP-----PAAPA-AGPPRRLTRPAVASLSESRESLPSPWDPAD 2806

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  640 YPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPmmqaaaaaagpplvaatPYSSYIPYNPQQFPGQPAMMQPMah 719
Cdd:PHA03247  2807 PPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG-----------------PPPPSLPLGGSVAPGGDVRRRPP-- 2867

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  720 yPSQPVFAPMLQSNP--RMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATqlhghQPQPATTPtgsQPQ 797
Cdd:PHA03247  2868 -SRSPAAKPAAPARPpvRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPP-----QPQPPPPP---PPR 2938

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422357  798 SQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLP-PGPSAQSPQSSFPQP 854
Cdd:PHA03247  2939 PQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPqPAPSREAPASSTPPL 2996
 
Name Accession Description Interval E-value
SM-ATX pfam14438
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
 35-108 3.04e-19

Ataxin 2 SM domain; This SM domain is found in Ataxin-2.


Pssm-ID: 464173  Cd Length: 78  Bit Score: 82.99  E-value: 3.04e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422357  35 MLHFLTAVVGSTCDVKVKNGTTYEGIFKTLS--SKFELAVDAVHRKASE--PAGGPRREDIVDTMVFKPSDVLLVHFR 108
Cdd:pfam14438   1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASleKDFGVVLKMARRIKKSngSGLNPVRGEIVDTMIFPAKDIVDIEAK 78
LsmAD pfam06741
LsmAD domain; This domain is found associated with Lsm domain.
 176-238 1.43e-17

LsmAD domain; This domain is found associated with Lsm domain.


Pssm-ID: 461998 [Multi-domain]  Cd Length: 65  Bit Score: 77.61  E-value: 1.43e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422357 176 YGVKTTYDSSLssYTVPLEKdNSEEFRQRELRAAQLAREIESSPQYRLRIAMEN-----DDGRTEEEK 238
Cdd:pfam06741   1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERgldvdDSGLDEEDK 65
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 663-882 9.78e-11

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 65.83  E-value: 9.78e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 663 PPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSyiPYNPQQFPGQPAMMQPMA--------------HYPSQPVFAP 728
Cdd:pfam09770 107 PAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRT--GYEKYKEPEPIPDLQVDAslwgvapkkaaapaPAPQPAAQPA 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 729 MLQSNPRMLTS--------------------GSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATQL--HGHQPQ 786
Cdd:pfam09770 185 SLPAPSRKMMSleeveaamraqakkpaqqpaPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHpgQGHPVT 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 787 PATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPqssfPQPAavyaiHPHQQL 866
Cdd:pfam09770 265 ILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQ----PAPA-----HQAHRQ 335

                         250
                  ....*....|....*.
gi 1720422357 867 PHGFTNMAHVTQAHVQ 882
Cdd:pfam09770 336 QGSFGRQAPIITHPQQ 351
PHA03247 PHA03247
large tegument protein UL36; Provisional
 248-854 3.09e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 58.03  E-value: 3.09e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  248 GRESPSLVSREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPgpgsearginggPSRMSPKAQRP 327
Cdd:PHA03247  2513 SRLAPAILPDEPVGEPVHPRMLTWIRGLEELASDDAGDPPPPLPPAAPPAAPDRSVP------------PPRPAPRPSEP 2580

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  328 LRGAKtlsspSNRPsgeaSVPPTSAVGRMY-----PPRSPKSAAPAPVSASCPEPPI--GSAVASSASIPVTSSVVDPGA 400
Cdd:PHA03247  2581 AVTSR-----ARRP----DAPPQSARPRAPvddrgDPRGPAPPSPLPPDTHAPDPPPpsPSPAANEPDPHPPPTVPPPER 2651

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  401 GSISPASPKLSLtptdvkelptkePSRnleAQELARIAGKVPGLQNEQKRfqleelrkfgaqfKLQPSSSPETGL-DPFP 479
Cdd:PHA03247  2652 PRDDPAPGRVSR------------PRR---ARRLGRAAQASSPPQRPRRR-------------AARPTVGSLTSLaDPPP 2703

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  480 srilkeeakgkekevdglltsdPMGSPVSSktesildkedkvPMAGVGGTEGPeqlPAPCPSQTGSPPVGLikgdekeeG 559
Cdd:PHA03247  2704 ----------------------PPPTPEPA------------PHALVSATPLP---PGPAAARQASPALPA--------A 2738

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  560 PVTEQVKKSTLNPNAKEFNPTKPLlsvnksTSTPTSPGPrthstPSIPVlTAGQSGLYSPQYISYIPQIHMGPAVQAPQM 639
Cdd:PHA03247  2739 PAPPAVPAGPATPGGPARPARPPT------TAGPPAPAP-----PAAPA-AGPPRRLTRPAVASLSESRESLPSPWDPAD 2806

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  640 YPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPmmqaaaaaagpplvaatPYSSYIPYNPQQFPGQPAMMQPMah 719
Cdd:PHA03247  2807 PPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG-----------------PPPPSLPLGGSVAPGGDVRRRPP-- 2867

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  720 yPSQPVFAPMLQSNP--RMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATqlhghQPQPATTPtgsQPQ 797
Cdd:PHA03247  2868 -SRSPAAKPAAPARPpvRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPP-----QPQPPPPP---PPR 2938

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422357  798 SQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLP-PGPSAQSPQSSFPQP 854
Cdd:PHA03247  2939 PQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPqPAPSREAPASSTPPL 2996
PHA03247 PHA03247
large tegument protein UL36; Provisional
 532-945 4.46e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.63  E-value: 4.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  532 PEQLPAPCPSQTGSPPVGLIKGDEKEEGPVTEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVlta 611
Cdd:PHA03247  2619 PDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSL--- 2695

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  612 gqSGLYSPQyisyipqihmgPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAAGPPLV 691
Cdd:PHA03247  2696 --TSLADPP-----------PPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPT 2762

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  692 AATPYSSYIPYNPqqfpgqPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYATVHQ 771
Cdd:PHA03247  2763 TAGPPAPAPPAAP------AAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQP 2836

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  772 SYPHHATQlhghQPQPATTPTGS---------QPQSQHAAPSPVQHQAGQAPHLGSGQPQQNlyhPGALTGTPPSLPPGP 842
Cdd:PHA03247  2837 TAPPPPPG----PPPPSLPLGGSvapggdvrrRPPSRSPAAKPAAPARPPVRRLARPAVSRS---TESFALPPDQPERPP 2909

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  843 SAQSPQSSFPQPAAVYAIHPHQQLPhgftnmahvtqahvqtgvTAAPPPHPGAPHPPQVMLLHPPQGHGGPPQGAVPPSG 922
Cdd:PHA03247  2910 QPQAPPPPQPQPQPPPPPQPQPPPP------------------PPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGR 2971

                          410       420
                   ....*....|....*....|...
gi 1720422357  923 VPALSASTPSPYPYIGHPQGEQP 945
Cdd:PHA03247  2972 VAVPRFRVPQPAPSREAPASSTP 2994
 
Name Accession Description Interval E-value
SM-ATX pfam14438
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
 35-108 3.04e-19

Ataxin 2 SM domain; This SM domain is found in Ataxin-2.


Pssm-ID: 464173  Cd Length: 78  Bit Score: 82.99  E-value: 3.04e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422357  35 MLHFLTAVVGSTCDVKVKNGTTYEGIFKTLS--SKFELAVDAVHRKASE--PAGGPRREDIVDTMVFKPSDVLLVHFR 108
Cdd:pfam14438   1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASleKDFGVVLKMARRIKKSngSGLNPVRGEIVDTMIFPAKDIVDIEAK 78
LsmAD pfam06741
LsmAD domain; This domain is found associated with Lsm domain.
 176-238 1.43e-17

LsmAD domain; This domain is found associated with Lsm domain.


Pssm-ID: 461998 [Multi-domain]  Cd Length: 65  Bit Score: 77.61  E-value: 1.43e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422357 176 YGVKTTYDSSLssYTVPLEKdNSEEFRQRELRAAQLAREIESSPQYRLRIAMEN-----DDGRTEEEK 238
Cdd:pfam06741   1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERgldvdDSGLDEEDK 65
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 663-882 9.78e-11

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 65.83  E-value: 9.78e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 663 PPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSyiPYNPQQFPGQPAMMQPMA--------------HYPSQPVFAP 728
Cdd:pfam09770 107 PAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRT--GYEKYKEPEPIPDLQVDAslwgvapkkaaapaPAPQPAAQPA 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 729 MLQSNPRMLTS--------------------GSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATQL--HGHQPQ 786
Cdd:pfam09770 185 SLPAPSRKMMSleeveaamraqakkpaqqpaPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHpgQGHPVT 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 787 PATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPqssfPQPAavyaiHPHQQL 866
Cdd:pfam09770 265 ILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQ----PAPA-----HQAHRQ 335

                         250
                  ....*....|....*.
gi 1720422357 867 PHGFTNMAHVTQAHVQ 882
Cdd:pfam09770 336 QGSFGRQAPIITHPQQ 351
PHA03247 PHA03247
large tegument protein UL36; Provisional
 248-854 3.09e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 58.03  E-value: 3.09e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  248 GRESPSLVSREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPgpgsearginggPSRMSPKAQRP 327
Cdd:PHA03247  2513 SRLAPAILPDEPVGEPVHPRMLTWIRGLEELASDDAGDPPPPLPPAAPPAAPDRSVP------------PPRPAPRPSEP 2580

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  328 LRGAKtlsspSNRPsgeaSVPPTSAVGRMY-----PPRSPKSAAPAPVSASCPEPPI--GSAVASSASIPVTSSVVDPGA 400
Cdd:PHA03247  2581 AVTSR-----ARRP----DAPPQSARPRAPvddrgDPRGPAPPSPLPPDTHAPDPPPpsPSPAANEPDPHPPPTVPPPER 2651

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  401 GSISPASPKLSLtptdvkelptkePSRnleAQELARIAGKVPGLQNEQKRfqleelrkfgaqfKLQPSSSPETGL-DPFP 479
Cdd:PHA03247  2652 PRDDPAPGRVSR------------PRR---ARRLGRAAQASSPPQRPRRR-------------AARPTVGSLTSLaDPPP 2703

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  480 srilkeeakgkekevdglltsdPMGSPVSSktesildkedkvPMAGVGGTEGPeqlPAPCPSQTGSPPVGLikgdekeeG 559
Cdd:PHA03247  2704 ----------------------PPPTPEPA------------PHALVSATPLP---PGPAAARQASPALPA--------A 2738

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  560 PVTEQVKKSTLNPNAKEFNPTKPLlsvnksTSTPTSPGPrthstPSIPVlTAGQSGLYSPQYISYIPQIHMGPAVQAPQM 639
Cdd:PHA03247  2739 PAPPAVPAGPATPGGPARPARPPT------TAGPPAPAP-----PAAPA-AGPPRRLTRPAVASLSESRESLPSPWDPAD 2806

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  640 YPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPmmqaaaaaagpplvaatPYSSYIPYNPQQFPGQPAMMQPMah 719
Cdd:PHA03247  2807 PPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG-----------------PPPPSLPLGGSVAPGGDVRRRPP-- 2867

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  720 yPSQPVFAPMLQSNP--RMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATqlhghQPQPATTPtgsQPQ 797
Cdd:PHA03247  2868 -SRSPAAKPAAPARPpvRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPP-----QPQPPPPP---PPR 2938

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422357  798 SQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLP-PGPSAQSPQSSFPQP 854
Cdd:PHA03247  2939 PQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPqPAPSREAPASSTPPL 2996
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 703-941 1.74e-06

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 51.96  E-value: 1.74e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 703 NPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSG----SHPQAI----VSSS------TPQYPAAEQPTPQALYAT 768
Cdd:pfam09770 106 QPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRTGyekyKEPEPIpdlqVDASlwgvapKKAAAPAPAPQPAAQPAS 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 769 VHQSYPHHAT------QLHGHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGP 842
Cdd:pfam09770 186 LPAPSRKMMSleeveaAMRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTI 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 843 SaQSPQSSFPQPAAVYA-IHPHQQLPHGFTNMAHVTQAHVQTGVtaappphpgaphppQVMLLHPPQGHGGPPQGAVPPS 921
Cdd:pfam09770 266 L-QRPQSPQPDPAQPSIqPQAQQFHQQPPPVPVQPTQILQNPNR--------------LSAARVGYPQNPQPGVQPAPAH 330

                         250       260
                  ....*....|....*....|
gi 1720422357 922 GVPALSASTPSPYPYIGHPQ 941
Cdd:pfam09770 331 QAHRQQGSFGRQAPIITHPQ 350
PHA03247 PHA03247
large tegument protein UL36; Provisional
 310-856 1.02e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.94  E-value: 1.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  310 ARGINGGPSRMSPKAQRPLRGAKTLSSPSNR--PSGEASVPPTSAVGRMYPPRSPKSAAPAPvsASCPEPPIGSAVASS- 386
Cdd:PHA03247  2456 ARTILGAPFSLSLLLGELFPGAPVYRRPAEArfPFAAGAAPDPGGGGPPDPDAPPAPSRLAP--AILPDEPVGEPVHPRm 2533

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  387 -ASIPVTSSVVDPGAGSISPASPKLSLTPTDVKELPTKEPS-RNLEAQELARiaGKVPGLQNEQKRFQLEELRKFGAQFK 464
Cdd:PHA03247  2534 lTWIRGLEELASDDAGDPPPPLPPAAPPAAPDRSVPPPRPApRPSEPAVTSR--ARRPDAPPQSARPRAPVDDRGDPRGP 2611

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  465 LQPSSSPETGLDPFPsrilkeeakgkekevdglltsdPMGSPVSSKTESILDKEDKVPmagvggtEGPEQLPAPCPSQTG 544
Cdd:PHA03247  2612 APPSPLPPDTHAPDP----------------------PPPSPSPAANEPDPHPPPTVP-------PPERPRDDPAPGRVS 2662

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  545 SPPVGLIKGDEKEEGPVTEQVKKSTLNPnakefnPTKPLLSVNKSTSTPTSPGPRTHS-TPSIPVLTAGQSGLYSPqyis 623
Cdd:PHA03247  2663 RPRRARRLGRAAQASSPPQRPRRRAARP------TVGSLTSLADPPPPPPTPEPAPHAlVSATPLPPGPAAARQAS---- 2732

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  624 yiPQIHMGPAVQAPQMYP-YPVSNSVPGQQGKYRGAKGSLPPQrsdqhQPASAPPMMQAAAAAAGPPLVAATPYSSYIPY 702
Cdd:PHA03247  2733 --PALPAAPAPPAVPAGPaTPGGPARPARPPTTAGPPAPAPPA-----APAAGPPRRLTRPAVASLSESRESLPSPWDPA 2805

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  703 NPQQFPGQPAMMQPMAHYPSQPVFAPM-LQSNPRMLTSGSHPQ--AIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATQ 779
Cdd:PHA03247  2806 DPPAAVLAPAAALPPAASPAGPLPPPTsAQPTAPPPPPGPPPPslPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRR 2885

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720422357  780 LHGHQPQPattPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAA 856
Cdd:PHA03247  2886 LARPAVSR---STESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAV 2959
PHA03247 PHA03247
large tegument protein UL36; Provisional
 532-945 4.46e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.63  E-value: 4.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  532 PEQLPAPCPSQTGSPPVGLIKGDEKEEGPVTEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVlta 611
Cdd:PHA03247  2619 PDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSL--- 2695

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  612 gqSGLYSPQyisyipqihmgPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAAGPPLV 691
Cdd:PHA03247  2696 --TSLADPP-----------PPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPT 2762

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  692 AATPYSSYIPYNPqqfpgqPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYATVHQ 771
Cdd:PHA03247  2763 TAGPPAPAPPAAP------AAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQP 2836

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  772 SYPHHATQlhghQPQPATTPTGS---------QPQSQHAAPSPVQHQAGQAPHLGSGQPQQNlyhPGALTGTPPSLPPGP 842
Cdd:PHA03247  2837 TAPPPPPG----PPPPSLPLGGSvapggdvrrRPPSRSPAAKPAAPARPPVRRLARPAVSRS---TESFALPPDQPERPP 2909

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  843 SAQSPQSSFPQPAAVYAIHPHQQLPhgftnmahvtqahvqtgvTAAPPPHPGAPHPPQVMLLHPPQGHGGPPQGAVPPSG 922
Cdd:PHA03247  2910 QPQAPPPPQPQPQPPPPPQPQPPPP------------------PPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGR 2971

                          410       420
                   ....*....|....*....|...
gi 1720422357  923 VPALSASTPSPYPYIGHPQGEQP 945
Cdd:PHA03247  2972 VAVPRFRVPQPAPSREAPASSTP 2994
PHA03247 PHA03247
large tegument protein UL36; Provisional
 461-950 5.94e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.24  E-value: 5.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  461 AQFKLQPSSSPETGLDPFPSrilKEEAKGKEKEVDGLLTSDPMGSPVSSKTESILDKEDKVPMAGVGGTEG--PEQLPAP 538
Cdd:PHA03247  2486 ARFPFAAGAAPDPGGGGPPD---PDAPPAPSRLAPAILPDEPVGEPVHPRMLTWIRGLEELASDDAGDPPPplPPAAPPA 2562

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  539 CPSQTGSPPvglikgdEKEEGPVTEQVKKSTLNPNAKEfNPTKPLLSVNKSTSTPTSPGPrTHSTPSIPVLTAGQSGLYS 618
Cdd:PHA03247  2563 APDRSVPPP-------RPAPRPSEPAVTSRARRPDAPP-QSARPRAPVDDRGDPRGPAPP-SPLPPDTHAPDPPPPSPSP 2633

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  619 PQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQ-QGKYRGAKGSLPPQRSDQHQ---PASAPPMMQAAAAAAGPPLVAAT 694
Cdd:PHA03247  2634 AANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRaRRLGRAAQASSPPQRPRRRAarpTVGSLTSLADPPPPPPTPEPAPH 2713

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  695 PYSSYIPYNP-QQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPAAeQPTPQALYATVhqsy 773
Cdd:PHA03247  2714 ALVSATPLPPgPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAA-GPPRRLTRPAV---- 2788

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  774 phhatqlhghqpQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQS------- 846
Cdd:PHA03247  2789 ------------ASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSlplggsv 2856

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  847 -----------PQSSFPQPAAVYAIhPHQQLPHGFTNMAHVTQAHVQTGVTAAPPPHPGAPHPPQVMLLHPPQGHGGPPQ 915
Cdd:PHA03247  2857 apggdvrrrppSRSPAAKPAAPARP-PVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP 2935

                          490       500       510
                   ....*....|....*....|....*....|....*
gi 1720422357  916 GAVPPSGVPALSASTPSPYPYIGHPQGEQPGQAPG 950
Cdd:PHA03247  2936 PPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPG 2970
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
782-857 1.13e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 45.92  E-value: 1.13e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720422357 782 GHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAphlgSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAV 857
Cdd:PRK14971  389 APQPSAAAAASPSPSQSSAAAQPSAPQSATQP----AGTPPTVSVDPPAAVPVNPPSTAPQAVRPAQFKEEKKIPV 460
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 286-607 1.26e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 46.22  E-value: 1.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 286 PGLSSLPPRGPHHLDNSS----PGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP--SGEASVPPTSAVGRmyPP 359
Cdd:PTZ00449  514 PEASGLPPKAPGDKEGEEgeheDSKESDEPKEGGKPGETKEGEVGKKPGPAKEHKPSKIPtlSKKPEFPKDPKHPK--DP 591

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 360 RSPKSAApAPVSASCPEPPIGSAVASSASIPVTSSVVDPGAGSISPASPKLSLT---PTDVKELPTKEPSRnleaqelar 436
Cdd:PTZ00449  592 EEPKKPK-RPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSperPEGPKIIKSPKPPK--------- 661

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 437 iAGKVPglqneqkrFQLEELRKFGAQFKLQPSSSPETGLDPFPSRILKEEAKGKEKEVDGLLTSDPMG-SPVSSKTESIL 515
Cdd:PTZ00449  662 -SPKPP--------FDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPlPPKLPRDEEFP 732

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 516 DKEDKVPMAgvggtegpeqlPAPCPSQTGSPPVGL------IKGDEKEEGPVTEQVKKSTLNPNAKEfnPTKPLLSVNKS 589
Cdd:PTZ00449  733 FEPIGDPDA-----------EQPDDIEFFTPPEEErtffheTPADTPLPDILAEEFKEEDIHAETGE--PDEAMKRPDSP 799

                         330
                  ....*....|....*....
gi 1720422357 590 TS-TPTSPGprTHstPSIP 607
Cdd:PTZ00449  800 SEhEDKPPG--DH--PSLP 814
Herpes_TAF50 pfam03326
Herpesvirus transcription activation factor (transactivator); This family includes EBV BRLF1 ...
 532-828 1.81e-04

Herpesvirus transcription activation factor (transactivator); This family includes EBV BRLF1 and similar ORF 50 proteins from other herpesviruses.


Pssm-ID: 308764 [Multi-domain]  Cd Length: 568  Bit Score: 45.46  E-value: 1.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 532 PEQLPAPCPSQTGSPP----VGLIKGDEKEEGPVTEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP 607
Cdd:pfam03326 269 PQRLQAPGFSRSTSRPargqTAQYFLAAQQHGVVSLFPSTATLVPIAGSTGVTEVVSYGHNSTSPSSTPCPSTAVTEADH 348

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 608 VLTAGQSGLYSPQYISYipQIHMGPAVQAPQMYPYPvsnsvpgqqGKYRGAKGsLPPQRSDQHQPAsappmmqAAAAAAG 687
Cdd:pfam03326 349 QTEPEVPWIATAHQESD--QRPIGPGPEKPTFLPPV---------GGKQFFQG-LRDSRSTSFLTA-------PEATSAI 409

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 688 PPLVAATPYSSYIPYNPQQFPGQPammqpmahypsqpvfapmlqSNPRMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYA 767
Cdd:pfam03326 410 SDVFQGTEVCQPKRIRALHPPGSP--------------------SANRPLPSSLAPTPTGPVHEPGSSLTPATVPQPLDA 469

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720422357 768 T--VHQSYPHHATQLHGHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHP 828
Cdd:pfam03326 470 ApvATPEASHELQPPDEETPQPLDEDQALCGQQDASHPPPRGQLDELTTTLESMTEDLNLDSP 532
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 753-955 1.99e-04

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 45.41  E-value: 1.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 753 QYPAAEQPTPQALYATVHQSYPHHATQLHGHQPQPATT---------------------PTGSQPQSQHAAPSPVQHQAG 811
Cdd:pfam09770 105 QQPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRTgyekykepepipdlqvdaslwGVAPKKAAAPAPAPQPAAQPA 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 812 QAPHLG-------------SGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHPHQQLPHGFTNMAHVTQ 878
Cdd:pfam09770 185 SLPAPSrkmmsleeveaamRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVT 264

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720422357 879 AHVQTGVTAAPPPHPGAPHPPQVMLLHPPQGHGGPPQGAVPPSGVPALSASTPSPYPYIGHPQGEQPG--QAPGFPGGA 955
Cdd:pfam09770 265 ILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQPAPAHQAhrQQGSFGRQA 343
PRK10927 PRK10927
cell division protein FtsN;
753-856 2.68e-04

cell division protein FtsN;


Pssm-ID: 236797 [Multi-domain]  Cd Length: 319  Bit Score: 44.29  E-value: 2.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 753 QYPAAEQPTPQalyatvHQSYPHHATQLHGHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALT 832
Cdd:PRK10927  144 QTPEQRQQTLQ------RQRQAQQLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASTQQPYQDLLQTPAHT 217

                          90       100
                  ....*....|....*....|....*
gi 1720422357 833 GTPPSLP-PGPSAQSPQSsfPQPAA 856
Cdd:PRK10927  218 TAQSKPQqAAPVTRAADA--PKPTA 240
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 705-862 3.37e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 44.69  E-value: 3.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  705 QQFPG-QPAMMQPMAHypSQPVFAPMlqsnPRMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATQLHGH 783
Cdd:PRK10263   709 QRYSGeQPAGANPFSL--DDFEFSPM----KALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQ 782

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720422357  784 QPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQnlyhpgaltgtpPSLPPGPSAQSPQSSFPQPAAVYaIHP 862
Cdd:PRK10263   783 QPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQ------------PVAPQPQYQQPQQPVAPQPQDTL-LHP 848
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 645-952 4.74e-04

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 44.37  E-value: 4.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 645 SNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSYIPYNPQQFP-GQPAMMQPMAHYPSQ 723
Cdd:pfam03154 145 SPSIPSPQDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPqGSPATSQPPNQTQST 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 724 PVFAPMLQSNPRMltsgsHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATQLHGHQPQPATTPTGSQPQSQHAAP 803
Cdd:pfam03154 225 AAPHTLIQQTPTL-----HPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFP 299

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 804 SPVQHQAGQAPHLgsgqPQQNLYHPGALTG-TPPSLPPGPSAQSPQSSFPQPAAVYAIH----PHQQLPHGFTNMAHVTQ 878
Cdd:pfam03154 300 LTPQSSQSQVPPG----PSPAAPGQSQQRIhTPPSQSQLQSQQPPREQPLPPAPLSMPHikppPTTPIPQLPNPQSHKHP 375

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 879 AHVQT----GVTAAPPPHPGAPHPPQVMLLHPPQGHGGP----PQGA---VPPSGVPALSASTPSPYPYIGHPQGEQPGQ 947
Cdd:pfam03154 376 PHLSGpspfQMNSNLPPPPALKPLSSLSTHHPPSAHPPPlqlmPQSQqlpPPPAQPPVLTQSQSLPPPAASHPPTSGLHQ 455


                  ....*
gi 1720422357 948 APGFP 952
Cdd:pfam03154 456 VPSQS 460
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
327-463 7.21e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 43.61  E-value: 7.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 327 PLRGAKTLSSPSNRPSGEASVPPTSAVGRMYPPRS---PKSAAPAPVSASCPEPPIGSaVASSASIPVTSSVVDPGAGSI 403
Cdd:PRK14971  371 GGRGPKQHIKPVFTQPAAAPQPSAAAAASPSPSQSsaaAQPSAPQSATQPAGTPPTVS-VDPPAAVPVNPPSTAPQAVRP 449

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720422357 404 SPASPKLSLTPTDV--KELPTKEPSRNLEAQELARIAGKVPGLQNEQkrFQLEELRKFGAQF 463
Cdd:PRK14971  450 AQFKEEKKIPVSKVssLGPSTLRPIQEKAEQATGNIKEAPTGTQKEI--FTEEDLQYYWQEF 509
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
301-435 3.43e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.40  E-value: 3.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 301 NSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGEASVPPTSAVGRMYPPRSPKSAA-------------P 367
Cdd:PRK12323  371 GAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAArqasargpggapaP 450

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422357 368 APVSASCPEPPIGSAVASSASIPVTSSVVDPGAGSISPASPKLSLTPTdVKELPTKEPSRNLEAQELA 435
Cdd:PRK12323  451 APAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPP-WEELPPEFASPAPAQPDAA 517
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 239-427 3.77e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 41.31  E-value: 3.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  239 HSAVQRQGSGRESPSLVSREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPR------GPHHLDNSSPGPGSEARG 312
Cdd:PHA03307   171 QAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRsaaddaGASSSDSSSSESSGCGWG 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357  313 INGGPSRMSPKAQRPLRGAKTLSSPSNRPSGEASVPPTSAVGRMYPPRSPKSA-------APAPVSASCPEPPIGSAVAS 385
Cdd:PHA03307   251 PENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPgsgpapsSPRASSSSSSSRESSSSSTS 330

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1720422357  386 SASIPVTSSVVDPGAGSISPASPKLSLTPTDVKELPTKEPSR 427
Cdd:PHA03307   331 SSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPS 372
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
 306-442 4.30e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 40.85  E-value: 4.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 306 PGSEARGINGGPSRMSPKAQRPLRGAKTlSSPSNRPSGEASVPPTSAVGRMYPPRSPKSAAPA--------PVSASCPEP 377
Cdd:PRK08691  364 ASCDANAVIENTELQSPSAQTAEKETAA-KKPQPRPEAETAQTPVQTASAAAMPSEGKTAGPVsnqenndvPPWEDAPDE 442

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720422357 378 ---PIGSAVASSASIPVTSSVVDPGAGSISPASPKLSLTPTDVKELPTKEPSR---NLEAQELARIAGKVP 442
Cdd:PRK08691  443 aqtAAGTAQTSAKSIQTASEAETPPENQVSKNKAADNETDAPLSEVPSENPIQatpNDEAVETETFAHEAP 513
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 739-958 4.32e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 4.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 739 SGSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSyphhatqlhghQPQPATTPTGSQPQSQHAAPSPVQHqAGQAPHLGS 818
Cdd:PRK07764  592 PGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPA-----------APAPAGAAAAPAEASAAPAPGVAAP-EHHPKHVAV 659

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 819 GQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHPHQQLPHGFTNMAHVTQAHVQTGVTAAPPPHPGAPHP 898
Cdd:PRK07764  660 PDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPV 739

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 899 PQVMLLHPPQGHGGPPQGAVPPSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDR 958
Cdd:PRK07764  740 PLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRR 799
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 247-426 4.65e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.83  E-value: 4.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 247 SGRESPSLVSREGKYIPLPQRVREGPRGGvRCSSSRGGRPglSSLP-----PRGP----HHLDNSSPGPGSEARGINGGP 317
Cdd:PTZ00449  531 EGEHEDSKESDEPKEGGKPGETKEGEVGK-KPGPAKEHKP--SKIPtlskkPEFPkdpkHPKDPEEPKKPKRPRSAQRPT 607

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 318 SRMSPKAQRPLRGAKTLSSPSNRPSGEASVPPTSAVGRMYP--PRSPKSAAPaPVSascPEPPIG-----------SAVA 384
Cdd:PTZ00449  608 RPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPegPKIIKSPKP-PKS---PKPPFDpkfkekfyddyLDAA 683

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1720422357 385 SSASIPVTSSVVDPGAGSISPAS-PKLSLTP-TDVKELPTKEPS 426
Cdd:PTZ00449  684 AKSKETKTTVVLDESFESILKETlPETPGTPfTTPRPLPPKLPR 727
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
663-856 4.66e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.01  E-value: 4.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 663 PPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSH 742
Cdd:PRK12323  365 PGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGP 444

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422357 743 PQAIVSSSTP-------QYPAAEQPTPQALYATVHQSYPHHATQlhgHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPH 815
Cdd:PRK12323  445 GGAPAPAPAPaaapaaaARPAAAGPRPVAAAAAAAPARAAPAAA---PAPADDDPPPWEELPPEFASPAPAQPDAAPAGW 521

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1720422357 816 LGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAA 856
Cdd:PRK12323  522 VAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVA 562
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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