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Conserved domains on  [gi|1717019477|ref|XP_030061762|]
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complement factor H isoform X6 [Microcaecilia unicolor]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 685-909 3.70e-28

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 115.14  E-value: 3.70e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  685 NAETVPSKDYYNGDTVKYICNENCQLQ--GKEEIECKNEKWTSPPRCIKstEKCPYPPELHNTVEQNLKDHFNENDTvhF 762
Cdd:PHA02927    35 SVETDANANYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGWTLFNQCIK--RRCPSPRDIDNGQLDIGGVDFGSSIT--Y 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  763 KCHETFILHGSESIQCRKGS-----WTSPPQCIETQVCKQPPTINNGKAaTPLKPSYSDGDIVIYNCDSGYQAEESNEIT 837
Cdd:PHA02927   111 SCNSGYQLIGESKSYCELGStgsmvWNPEAPICESVKCQSPPSISNGRH-NGYEDFYTDGSVVTYSCNSGYSLIGNSGVL 189

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1717019477  838 CTGGKWSTPPQCketQVCKQP-PTINNGKAATPLKPSYSDGDTVIYNCDSGYQAEESNEITCTGGKWSTP--PQC 909
Cdd:PHA02927   190 CSGGEWSDPPTC---QIVKCPhPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPelPKC 261
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 25-268 3.06e-26

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 109.36  E-value: 3.06e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477   25 PDSIPIAELVGEWDKESYPHGTEATYLCRPGY--IKVGRILWKCLNGEWKEVNpmvKCRNKPCGHPGDLLYGSFDLTrGT 102
Cdd:PHA02927    27 PINMKFKNSVETDANANYNIGDTIEYLCLPGYrkQKMGPIYAKCTGTGWTLFN---QCIKRRCPSPRDIDNGQLDIG-GV 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  103 DFvfGSRVEYQCDDGYQMISRV-NYRECTATG---WNNYVPQCEVRKCLPVQPPQNGRIvmtsiSDVDEEYPYGYILLFE 178
Cdd:PHA02927   103 DF--GSSITYSCNSGYQLIGESkSYCELGSTGsmvWNPEAPICESVKCQSPPSISNGRH-----NGYEDFYTDGSVVTYS 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  179 CDSpNYKLSGPNELYCmKSGEWSaDVPACEVISCQEPSIPNGKMMSRLPRkmQYENKERIQYECDPGYKHESRGYSECI- 257
Cdd:PHA02927   176 CNS-GYSLIGNSGVLC-SGGEWS-DPPTCQIVKCPHPTISNGYLSSGFKR--SYSYNDNVDFKCKYGYKLSGSSSSTCSp 250

                          250
                   ....*....|..
gi 1717019477  258 ENGWNPA-PSCI 268
Cdd:PHA02927   251 GNTWQPElPKCV 262
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 405-629 4.32e-16

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 79.70  E-value: 4.32e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  405 NGYPESSAARYQVGDKGRYSCYQGYSTpEGMSSGEIECLKNGWSVQPTCIK-ICTKPV-LHHGHYSDKPVFMaGDILQYE 482
Cdd:PHA02927    34 NSVETDANANYNIGDTIEYLCLPGYRK-QKMGPIYAKCTGTGWTLFNQCIKrRCPSPRdIDNGQLDIGGVDF-GSSITYS 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  483 CDEGYMTsdrnIIERLKCTESGWT-------KTPECIAITCSVDDEIPNGVSTPQKEEYENGHVLKFSCNENYKIKGEEL 555
Cdd:PHA02927   112 CNSGYQL----IGESKSYCELGSTgsmvwnpEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSG 187

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1717019477  556 RQCYYFGWfpKTLPQCIEITCKRPS-RKGALLSPHLQIYKHLDTVNISCEDGYKINGSDLIQCYSFG-WYPKPPTC 629
Cdd:PHA02927   188 VLCSGGEW--SDPPTCQIVKCPHPTiSNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNtWQPELPKC 261
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 1065-1209 6.39e-10

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 61.21  E-value: 6.39e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477 1065 GSFITFKCKTGFSPVPRQNMKMKCHDT-RLTYPKCTSSTPSKSCGPPLAIENGGISGTSiSDYVHGSSVEYRCARYYKLK 1143
Cdd:PHA02927   105 GSSITYSCNSGYQLIGESKSYCELGSTgSMVWNPEAPICESVKCQSPPSISNGRHNGYE-DFYTDGSVVTYSCNSGYSLI 183

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1717019477 1144 DPKPVVCNDGEWSNPPECvepctlnedQIFK------NNIVLSRQHRNEmfYTHMGFVEFECKYGYRFQGTS 1209
Cdd:PHA02927   184 GNSGVLCSGGEWSDPPTC---------QIVKcphptiSNGYLSSGFKRS--YSYNDNVDFKCKYGYKLSGSS 244
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 916-970 3.74e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 53.62  E-value: 3.74e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477  916 CDQPPSISNGAIQGSeLRKYKAGQSVTYRCINYYVMDGSPTVTCL-QGRWSQ-PPTC 970
Cdd:cd00033      1 CPPPPVPENGTVTGS-KGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPpPPTC 56
PHA02639 super family cl31493
EEV host range protein; Provisional
 212-395 4.16e-06

EEV host range protein; Provisional


The actual alignment was detected with superfamily member PHA02639:

Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 50.05  E-value: 4.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  212 CQEPSIPNGKMMSRLPRKmqYENKERIQYECDPGYKHESRGYSECIENG----W-NPAPSCIEIVCSFQ-NVVNGNLQPE 285
Cdd:PHA02639    22 CDKPDDISNGFITELMEK--YEIGKLIEYTCNTDYALIGDRFRTCIKDKnnaiWsNKAPFCMLKECNDPpSIINGKIYNK 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  286 KNVYRENERVNLICNKGYQPEYK---DEFPKCTK-TGWS-SPLLCVHKDCSFPEIENGRLlqTQYSTYKNYYFPMRKGrk 360
Cdd:PHA02639   100 REMYKVGDEIYYVCNEHKGVQYSlvgNEKITCIQdKSWKpDPPICKMINCRFPALQNGYI--NGIPSNKKFYYKTRVG-- 175

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1717019477  361 idYICTEGF-FTEEGNSWGGIECTdegWSP-VPKCIK 395
Cdd:PHA02639   176 --FSCKSGFdLVGEKYSTCNINAT---WFPsIPTCVR 207
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 685-909 3.70e-28

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 115.14  E-value: 3.70e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  685 NAETVPSKDYYNGDTVKYICNENCQLQ--GKEEIECKNEKWTSPPRCIKstEKCPYPPELHNTVEQNLKDHFNENDTvhF 762
Cdd:PHA02927    35 SVETDANANYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGWTLFNQCIK--RRCPSPRDIDNGQLDIGGVDFGSSIT--Y 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  763 KCHETFILHGSESIQCRKGS-----WTSPPQCIETQVCKQPPTINNGKAaTPLKPSYSDGDIVIYNCDSGYQAEESNEIT 837
Cdd:PHA02927   111 SCNSGYQLIGESKSYCELGStgsmvWNPEAPICESVKCQSPPSISNGRH-NGYEDFYTDGSVVTYSCNSGYSLIGNSGVL 189

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1717019477  838 CTGGKWSTPPQCketQVCKQP-PTINNGKAATPLKPSYSDGDTVIYNCDSGYQAEESNEITCTGGKWSTP--PQC 909
Cdd:PHA02927   190 CSGGEWSDPPTC---QIVKCPhPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPelPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 25-268 3.06e-26

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 109.36  E-value: 3.06e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477   25 PDSIPIAELVGEWDKESYPHGTEATYLCRPGY--IKVGRILWKCLNGEWKEVNpmvKCRNKPCGHPGDLLYGSFDLTrGT 102
Cdd:PHA02927    27 PINMKFKNSVETDANANYNIGDTIEYLCLPGYrkQKMGPIYAKCTGTGWTLFN---QCIKRRCPSPRDIDNGQLDIG-GV 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  103 DFvfGSRVEYQCDDGYQMISRV-NYRECTATG---WNNYVPQCEVRKCLPVQPPQNGRIvmtsiSDVDEEYPYGYILLFE 178
Cdd:PHA02927   103 DF--GSSITYSCNSGYQLIGESkSYCELGSTGsmvWNPEAPICESVKCQSPPSISNGRH-----NGYEDFYTDGSVVTYS 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  179 CDSpNYKLSGPNELYCmKSGEWSaDVPACEVISCQEPSIPNGKMMSRLPRkmQYENKERIQYECDPGYKHESRGYSECI- 257
Cdd:PHA02927   176 CNS-GYSLIGNSGVLC-SGGEWS-DPPTCQIVKCPHPTISNGYLSSGFKR--SYSYNDNVDFKCKYGYKLSGSSSSTCSp 250

                          250
                   ....*....|..
gi 1717019477  258 ENGWNPA-PSCI 268
Cdd:PHA02927   251 GNTWQPElPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 405-629 4.32e-16

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 79.70  E-value: 4.32e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  405 NGYPESSAARYQVGDKGRYSCYQGYSTpEGMSSGEIECLKNGWSVQPTCIK-ICTKPV-LHHGHYSDKPVFMaGDILQYE 482
Cdd:PHA02927    34 NSVETDANANYNIGDTIEYLCLPGYRK-QKMGPIYAKCTGTGWTLFNQCIKrRCPSPRdIDNGQLDIGGVDF-GSSITYS 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  483 CDEGYMTsdrnIIERLKCTESGWT-------KTPECIAITCSVDDEIPNGVSTPQKEEYENGHVLKFSCNENYKIKGEEL 555
Cdd:PHA02927   112 CNSGYQL----IGESKSYCELGSTgsmvwnpEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSG 187

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1717019477  556 RQCYYFGWfpKTLPQCIEITCKRPS-RKGALLSPHLQIYKHLDTVNISCEDGYKINGSDLIQCYSFG-WYPKPPTC 629
Cdd:PHA02927   188 VLCSGGEW--SDPPTCQIVKCPHPTiSNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNtWQPELPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 1065-1209 6.39e-10

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 61.21  E-value: 6.39e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477 1065 GSFITFKCKTGFSPVPRQNMKMKCHDT-RLTYPKCTSSTPSKSCGPPLAIENGGISGTSiSDYVHGSSVEYRCARYYKLK 1143
Cdd:PHA02927   105 GSSITYSCNSGYQLIGESKSYCELGSTgSMVWNPEAPICESVKCQSPPSISNGRHNGYE-DFYTDGSVVTYSCNSGYSLI 183

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1717019477 1144 DPKPVVCNDGEWSNPPECvepctlnedQIFK------NNIVLSRQHRNEmfYTHMGFVEFECKYGYRFQGTS 1209
Cdd:PHA02927   184 GNSGVLCSGGEWSDPPTC---------QIVKcphptiSNGYLSSGFKRS--YSYNDNVDFKCKYGYKLSGSS 244
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 916-970 3.74e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 53.62  E-value: 3.74e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477  916 CDQPPSISNGAIQGSeLRKYKAGQSVTYRCINYYVMDGSPTVTCL-QGRWSQ-PPTC 970
Cdd:cd00033      1 CPPPPVPENGTVTGS-KGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPpPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 855-910 6.94e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 52.85  E-value: 6.94e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1717019477  855 CKQPPTINNGKAaTPLKPSYSDGDTVIYNCDSGYQAEESNEITCT-GGKWS-TPPQCK 910
Cdd:cd00033      1 CPPPPVPENGTV-TGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 855-909 1.36e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.14  E-value: 1.36e-08
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477   855 CKQPPTINNGKAaTPLKPSYSDGDTVIYNCDSGYQAEESNEITCT-GGKWS-TPPQC 909
Cdd:smart00032    1 CPPPPDIENGTV-TSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
855-909 3.92e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 50.96  E-value: 3.92e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477  855 CKQPPTINNGKAaTPLKPSYSDGDTVIYNCDSGYQAEESNEITCTG-GKWS-TPPQC 909
Cdd:pfam00084    1 CPPPPDIPNGKV-SATKNEYNYGASVSYECDPGYRLVGSPTITCQEdGTWSpPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 146-208 1.25e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.38  E-value: 1.25e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1717019477  146 CLPVQPPQNGRIVMTSisdvdEEYPYGYILLFECDsPNYKLSGPNELYCMKSGEWSADVPACE 208
Cdd:cd00033      1 CPPPPVPENGTVTGSK-----GSYSYGSTVTYSCN-EGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 916-970 2.09e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 48.68  E-value: 2.09e-07
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477   916 CDQPPSISNGAIQGSElRKYKAGQSVTYRCINYYVMDGSPTVTCL-QGRWS-QPPTC 970
Cdd:smart00032    1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 1107-1162 2.73e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 48.61  E-value: 2.73e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1717019477 1107 CGPPLAIENGGISGTSiSDYVHGSSVEYRCARYYKLKDPKPVVCN-DGEWSN-PPECV 1162
Cdd:cd00033      1 CPPPPVPENGTVTGSK-GSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPpPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
916-970 7.64e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.11  E-value: 7.64e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477  916 CDQPPSISNGAIQGSELRkYKAGQSVTYRCINYYVMDGSPTVTCLQ-GRWSQP-PTC 970
Cdd:pfam00084    1 CPPPPDIPNGKVSATKNE-YNYGASVSYECDPGYRLVGSPTITCQEdGTWSPPfPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 85-141 8.94e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 47.14  E-value: 8.94e-07
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 1717019477    85 CGHPGDLLYGSFDLTRGTdFVFGSRVEYQCDDGYQMISRvNYRECTATG-WNNYVPQC 141
Cdd:smart00032    1 CPPPPDIENGTVTSSSGT-YSYGDTVTYSCDPGYTLIGS-STITCLENGtWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 1107-1161 1.78e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 46.37  E-value: 1.78e-06
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477  1107 CGPPLAIENGGISGTSiSDYVHGSSVEYRCARYYKLKDPKPVVC-NDGEWSNP-PEC 1161
Cdd:smart00032    1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSPPpPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
85-141 2.41e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.95  E-value: 2.41e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1717019477   85 CGHPGDLLYGSFDLTRGtDFVFGSRVEYQCDDGYQMISRvNYRECTATG-WNNYVPQC 141
Cdd:pfam00084    1 CPPPPDIPNGKVSATKN-EYNYGASVSYECDPGYRLVGS-PTITCQEDGtWSPPFPEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 212-395 4.16e-06

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 50.05  E-value: 4.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  212 CQEPSIPNGKMMSRLPRKmqYENKERIQYECDPGYKHESRGYSECIENG----W-NPAPSCIEIVCSFQ-NVVNGNLQPE 285
Cdd:PHA02639    22 CDKPDDISNGFITELMEK--YEIGKLIEYTCNTDYALIGDRFRTCIKDKnnaiWsNKAPFCMLKECNDPpSIINGKIYNK 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  286 KNVYRENERVNLICNKGYQPEYK---DEFPKCTK-TGWS-SPLLCVHKDCSFPEIENGRLlqTQYSTYKNYYFPMRKGrk 360
Cdd:PHA02639   100 REMYKVGDEIYYVCNEHKGVQYSlvgNEKITCIQdKSWKpDPPICKMINCRFPALQNGYI--NGIPSNKKFYYKTRVG-- 175

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1717019477  361 idYICTEGF-FTEEGNSWGGIECTdegWSP-VPKCIK 395
Cdd:PHA02639   176 --FSCKSGFdLVGEKYSTCNINAT---WFPsIPTCVR 207
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 516-571 3.09e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.51  E-value: 3.09e-05
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 1717019477   516 CSVDDEIPNGVSTPQKEEYENGHVLKFSCNENYKIKGEELRQCYYFGWFPKTLPQC 571
Cdd:smart00032    1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
1107-1161 3.58e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.49  E-value: 3.58e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477 1107 CGPPLAIENGGISGTSiSDYVHGSSVEYRCARYYKLKDPKPVVC-NDGEWSNP-PEC 1161
Cdd:pfam00084    1 CPPPPDIPNGKVSATK-NEYNYGASVSYECDPGYRLVGSPTITCqEDGTWSPPfPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 579-630 1.23e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 40.91  E-value: 1.23e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1717019477  579 PSRKGALLSPHLQIYKHLDTVNISCEDGYKINGSDLIQCYSFG-WYPKPPTCQ 630
Cdd:cd00033      5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGgWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
516-571 8.42e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 38.63  E-value: 8.42e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1717019477  516 CSVDDEIPNGVSTPQKEEYENGHVLKFSCNENYKIKGEELRQCYYFGWFPKTLPQC 571
Cdd:pfam00084    1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 685-909 3.70e-28

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 115.14  E-value: 3.70e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  685 NAETVPSKDYYNGDTVKYICNENCQLQ--GKEEIECKNEKWTSPPRCIKstEKCPYPPELHNTVEQNLKDHFNENDTvhF 762
Cdd:PHA02927    35 SVETDANANYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGWTLFNQCIK--RRCPSPRDIDNGQLDIGGVDFGSSIT--Y 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  763 KCHETFILHGSESIQCRKGS-----WTSPPQCIETQVCKQPPTINNGKAaTPLKPSYSDGDIVIYNCDSGYQAEESNEIT 837
Cdd:PHA02927   111 SCNSGYQLIGESKSYCELGStgsmvWNPEAPICESVKCQSPPSISNGRH-NGYEDFYTDGSVVTYSCNSGYSLIGNSGVL 189

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1717019477  838 CTGGKWSTPPQCketQVCKQP-PTINNGKAATPLKPSYSDGDTVIYNCDSGYQAEESNEITCTGGKWSTP--PQC 909
Cdd:PHA02927   190 CSGGEWSDPPTC---QIVKCPhPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPelPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 729-970 2.21e-26

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 109.74  E-value: 2.21e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  729 CIKSTEKCPYPP---ELHNTVEQNLKDHFNENDTVHFKCHETFILH--GSESIQCRKGSWTSPPQCIETQvCKQPPTINN 803
Cdd:PHA02927    16 CVLSCCTIPSRPinmKFKNSVETDANANYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGWTLFNQCIKRR-CPSPRDIDN 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  804 GKaatpLKPSYSD-GDIVIYNCDSGYQAEESNEITCTGGK-----WSTPPQCKETQVCKQPPTINNGKAaTPLKPSYSDG 877
Cdd:PHA02927    95 GQ----LDIGGVDfGSSITYSCNSGYQLIGESKSYCELGStgsmvWNPEAPICESVKCQSPPSISNGRH-NGYEDFYTDG 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  878 DTVIYNCDSGYQAEESNEITCTGGKWSTPPQCKeaLATCDQpPSISNGAIQGSELRKYKAGQSVTYRCINYYVMDGSPTV 957
Cdd:PHA02927   170 SVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQ--IVKCPH-PTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSS 246

                          250
                   ....*....|....*
gi 1717019477  958 TCLQGRWSQP--PTC 970
Cdd:PHA02927   247 TCSPGNTWQPelPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 25-268 3.06e-26

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 109.36  E-value: 3.06e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477   25 PDSIPIAELVGEWDKESYPHGTEATYLCRPGY--IKVGRILWKCLNGEWKEVNpmvKCRNKPCGHPGDLLYGSFDLTrGT 102
Cdd:PHA02927    27 PINMKFKNSVETDANANYNIGDTIEYLCLPGYrkQKMGPIYAKCTGTGWTLFN---QCIKRRCPSPRDIDNGQLDIG-GV 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  103 DFvfGSRVEYQCDDGYQMISRV-NYRECTATG---WNNYVPQCEVRKCLPVQPPQNGRIvmtsiSDVDEEYPYGYILLFE 178
Cdd:PHA02927   103 DF--GSSITYSCNSGYQLIGESkSYCELGSTGsmvWNPEAPICESVKCQSPPSISNGRH-----NGYEDFYTDGSVVTYS 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  179 CDSpNYKLSGPNELYCmKSGEWSaDVPACEVISCQEPSIPNGKMMSRLPRkmQYENKERIQYECDPGYKHESRGYSECI- 257
Cdd:PHA02927   176 CNS-GYSLIGNSGVLC-SGGEWS-DPPTCQIVKCPHPTISNGYLSSGFKR--SYSYNDNVDFKCKYGYKLSGSSSSTCSp 250

                          250
                   ....*....|..
gi 1717019477  258 ENGWNPA-PSCI 268
Cdd:PHA02927   251 GNTWQPElPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 405-629 4.32e-16

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 79.70  E-value: 4.32e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  405 NGYPESSAARYQVGDKGRYSCYQGYSTpEGMSSGEIECLKNGWSVQPTCIK-ICTKPV-LHHGHYSDKPVFMaGDILQYE 482
Cdd:PHA02927    34 NSVETDANANYNIGDTIEYLCLPGYRK-QKMGPIYAKCTGTGWTLFNQCIKrRCPSPRdIDNGQLDIGGVDF-GSSITYS 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  483 CDEGYMTsdrnIIERLKCTESGWT-------KTPECIAITCSVDDEIPNGVSTPQKEEYENGHVLKFSCNENYKIKGEEL 555
Cdd:PHA02927   112 CNSGYQL----IGESKSYCELGSTgsmvwnpEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSG 187

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1717019477  556 RQCYYFGWfpKTLPQCIEITCKRPS-RKGALLSPHLQIYKHLDTVNISCEDGYKINGSDLIQCYSFG-WYPKPPTC 629
Cdd:PHA02927   188 VLCSGGEW--SDPPTCQIVKCPHPTiSNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNtWQPELPKC 261
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 740-980 2.63e-15

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 78.59  E-value: 2.63e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  740 PELHNTVEQNLKDHFNENDTVHFKCHETFILHGSESIqCRKGSWTSppqcieTQVCKQPPTINNGKAATPLKPSYSDGDI 819
Cdd:PHA02954    24 PTMNNAKLTSTETSFNDKQKVTFTCDSGYYSLDPNAV-CETDKWKY------ENPCKKMCTVSDYVSELYDKPLYEVNST 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  820 VIYNCDSG---YQAEESNEITctggKWSTPPQCKETQVckQPPTINNGkAATPLKPSYSDGDTVIYNCDSGYQAEESNEI 896
Cdd:PHA02954    97 ITLICKDEtkyFRCEEKNGNT----SWNDTVTCPNAEC--QPLQLEHG-SCQPVKEKYSFGEHITINCDVGYEVIGASYI 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  897 TCTGGKWSTPPQCKEalaTCDQpPSISNGAIQGSelrKYKAGQSVTYRCINYYVMDGSPTVTCLQGRWSqppTCFEPCTA 976
Cdd:PHA02954   170 SCTANSWNVIPSCQQ---KCDI-PSLSNGLISGS---TFSIGGVIHLSCKSGFTLTGSPSSTCIDGKWN---PVLPICVR 239


                   ....
gi 1717019477  977 SDEE 980
Cdd:PHA02954   240 SNEE 243
PHA02639 PHA02639
EEV host range protein; Provisional
 85-268 7.70e-13

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 70.85  E-value: 7.70e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477   85 CGHPGDLLYGsFDLTRGTDFVFGSRVEYQCDDGYQMIS---RVNYRECTATGWNNYVPQCEVRKClpVQPPQngrIVMTS 161
Cdd:PHA02639    22 CDKPDDISNG-FITELMEKYEIGKLIEYTCNTDYALIGdrfRTCIKDKNNAIWSNKAPFCMLKEC--NDPPS---IINGK 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  162 ISDVDEEYPYGYILLFECDSP---NYKLSGPNELYCMKSGEWSADVPACEVISCQEPSIPNGkMMSRLPRKMQYENKERI 238
Cdd:PHA02639    96 IYNKREMYKVGDEIYYVCNEHkgvQYSLVGNEKITCIQDKSWKPDPPICKMINCRFPALQNG-YINGIPSNKKFYYKTRV 174

                          170       180       190
                   ....*....|....*....|....*....|..
gi 1717019477  239 QYECDPGYKHESRGYSEC-IENGWNPA-PSCI 268
Cdd:PHA02639   175 GFSCKSGFDLVGEKYSTCnINATWFPSiPTCV 206
PHA02831 PHA02831
EEV host range protein; Provisional
 467-669 1.00e-11

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 66.94  E-value: 1.00e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  467 YSDKpVFMAGDILQYECDEGYmtsDRNIIerlKCTESGWTKTPECIAIT-CSVDDEIPNGVSTPQKEEYENGHVLKFSCN 545
Cdd:PHA02831    35 YENK-VYEENENLEYKCNNNF---DKVFV---TCNNGSWSTKNMCIGKRnCKDPVTILNGYIKNKKDQYSFGDSVTYACK 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  546 ----ENYKIKGEELRQCYYFGWFPKTlPQCIEITCKRPSRKGALLSPHLQIYKHLDTVNISCEDGYKINGSDLIQC-YSF 620
Cdd:PHA02831   108 vnklEKYSIVGNETVKCINKQWVPKY-PVCKLIRCKYPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCdINS 186

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1717019477  621 GWYPKPPTCQEvgdeeentngtvDENHGVKKPSKLPTDSANRTNTNDTS 669
Cdd:PHA02831   187 IWYPGIPKCVK------------DKVHNEIQPNYLFDDLDEDFNNSTTN 223
PHA02831 PHA02831
EEV host range protein; Provisional
 813-959 3.98e-11

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 65.01  E-value: 3.98e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  813 SYSDGDIVIYNCDSGYqaeESNEITCTGGKWSTPPQCKETQVCKQPPTINNGKAATPlKPSYSDGDTVIYNCD----SGY 888
Cdd:PHA02831    39 VYEENENLEYKCNNNF---DKVFVTCNNGSWSTKNMCIGKRNCKDPVTILNGYIKNK-KDQYSFGDSVTYACKvnklEKY 114

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1717019477  889 QAEESNEITCTGGKW-STPPQCKeaLATCdQPPSISNGAIQGSElRKYKAGQSVTYRCINYYVMDGSPTVTC 959
Cdd:PHA02831   115 SIVGNETVKCINKQWvPKYPVCK--LIRC-KYPALQNGFLNVFE-KKFYYGDIVNFKCKKGFILLGSSVSTC 182
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 670-904 5.13e-11

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 65.49  E-value: 5.13e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  670 LSGLVKKCPPAPQLENAETVPSKDYYNG-DTVKYICNENCQLQGKEEIeCKNEKWTSPPRCIKSTEKCPYPPELHNTVEQ 748
Cdd:PHA02954    13 LPAVVYSTCTVPTMNNAKLTSTETSFNDkQKVTFTCDSGYYSLDPNAV-CETDKWKYENPCKKMCTVSDYVSELYDKPLY 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  749 NLKDHFN---ENDTVHFKCHEtfilhgsesiQCRKGSWTSPPQCIETQVckQPPTINNGkAATPLKPSYSDGDIVIYNCD 825
Cdd:PHA02954    92 EVNSTITlicKDETKYFRCEE----------KNGNTSWNDTVTCPNAEC--QPLQLEHG-SCQPVKEKYSFGEHITINCD 158

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1717019477  826 SGYQAEESNEITCTGGKWSTPPQCKetQVCKQpPTINNGKAAtplKPSYSDGDTVIYNCDSGYQAEESNEITCTGGKWS 904
Cdd:PHA02954   159 VGYEVIGASYISCTANSWNVIPSCQ--QKCDI-PSLSNGLIS---GSTFSIGGVIHLSCKSGFTLTGSPSSTCIDGKWN 231
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 476-632 6.66e-11

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 64.29  E-value: 6.66e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  476 GDILQYECDEGYMTSDRNIIeRLKCTESGWTKTPECIAITCSVDDEIPNGVSTPQKEEYenGHVLKFSCNENYKIKGEEL 555
Cdd:PHA02927    47 GDTIEYLCLPGYRKQKMGPI-YAKCTGTGWTLFNQCIKRRCPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQLIGESK 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  556 RQCY--YFG---WFPKTlPQCIEITCKRP-SRKGALLSPHLQIYKHLDTVNISCEDGYKINGSDLIQCySFGWYPKPPTC 629
Cdd:PHA02927   124 SYCElgSTGsmvWNPEA-PICESVKCQSPpSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLC-SGGEWSDPPTC 201


                   ...
gi 1717019477  630 QEV 632
Cdd:PHA02927   202 QIV 204
PHA02831 PHA02831
EEV host range protein; Provisional
 754-898 2.47e-10

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 62.70  E-value: 2.47e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  754 FNENDTVHFKCHETFilhGSESIQCRKGSWTSPPQCIETQVCKQPPTINNGKAATPlKPSYSDGDIVIYNCD----SGYQ 829
Cdd:PHA02831    40 YEENENLEYKCNNNF---DKVFVTCNNGSWSTKNMCIGKRNCKDPVTILNGYIKNK-KDQYSFGDSVTYACKvnklEKYS 115

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  830 AEESNEITCTGGKW-STPPQCKETQvCKQpPTINNGKAATpLKPSYSDGDTVIYNCDSGYQAEESNEITC 898
Cdd:PHA02831   116 IVGNETVKCINKQWvPKYPVCKLIR-CKY-PALQNGFLNV-FEKKFYYGDIVNFKCKKGFILLGSSVSTC 182
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 1065-1209 6.39e-10

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 61.21  E-value: 6.39e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477 1065 GSFITFKCKTGFSPVPRQNMKMKCHDT-RLTYPKCTSSTPSKSCGPPLAIENGGISGTSiSDYVHGSSVEYRCARYYKLK 1143
Cdd:PHA02927   105 GSSITYSCNSGYQLIGESKSYCELGSTgSMVWNPEAPICESVKCQSPPSISNGRHNGYE-DFYTDGSVVTYSCNSGYSLI 183

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1717019477 1144 DPKPVVCNDGEWSNPPECvepctlnedQIFK------NNIVLSRQHRNEmfYTHMGFVEFECKYGYRFQGTS 1209
Cdd:PHA02927   184 GNSGVLCSGGEWSDPPTC---------QIVKcphptiSNGYLSSGFKRS--YSYNDNVDFKCKYGYKLSGSS 244
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 102-395 1.73e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 60.05  E-value: 1.73e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  102 TDFVFGSRVEYQCDDGY--QMISRVnYRECTATGWNNYvPQCEVRKCLPVQPPQNGRIvmtSISDVDeeypYGYILLFEC 179
Cdd:PHA02927    42 ANYNIGDTIEYLCLPGYrkQKMGPI-YAKCTGTGWTLF-NQCIKRRCPSPRDIDNGQL---DIGGVD----FGSSITYSC 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  180 DSpNYKLSGPNELYC----MKSGEWSADVPACEVISCQEP-SIPNGKmmsrlprkmqyenkeriqyecdpgykhesrgys 254
Cdd:PHA02927   113 NS-GYQLIGESKSYCelgsTGSMVWNPEAPICESVKCQSPpSISNGR--------------------------------- 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  255 eciENGWNpapscieivcsfqnvvngnlqpekNVYRENERVNLICNKGYQPeYKDEFPKCTKTGWSSPLLCVHKDCSFPE 334
Cdd:PHA02927   159 ---HNGYE------------------------DFYTDGSVVTYSCNSGYSL-IGNSGVLCSGGEWSDPPTCQIVKCPHPT 210

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1717019477  335 IENGRLlqtqYSTYKNYYfpmRKGRKIDYICTEGFFTEEGNSwggIECTDEG-WSP-VPKCIK 395
Cdd:PHA02927   211 ISNGYL----SSGFKRSY---SYNDNVDFKCKYGYKLSGSSS---STCSPGNtWQPeLPKCVR 263
PHA02817 PHA02817
EEV Host range protein; Provisional
 141-269 3.57e-09

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 58.41  E-value: 3.57e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  141 CEVRKClpVQPPQngrIVMTSISDVDEEYPYGYILLFECDSPN----YKLSGPNELYCMKSGEWSADVPACEVISCQEPS 216
Cdd:PHA02817    19 CDLNKC--CYPPS---IKNGYIYNKKTEYNIGSNVTFFCGNNTrgvrYTLVGEKNIICEKDGKWNKEFPVCKIIRCRFPA 93

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1717019477  217 IPNGkMMSRLPRKMQYENKERIQYECDPGYKHESRGYSEC-IENGWNP-APSCIE 269
Cdd:PHA02817    94 LQNG-FVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCgINSSWIPkVPICSR 147
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 916-970 3.74e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 53.62  E-value: 3.74e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477  916 CDQPPSISNGAIQGSeLRKYKAGQSVTYRCINYYVMDGSPTVTCL-QGRWSQ-PPTC 970
Cdd:cd00033      1 CPPPPVPENGTVTGS-KGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPpPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 855-910 6.94e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 52.85  E-value: 6.94e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1717019477  855 CKQPPTINNGKAaTPLKPSYSDGDTVIYNCDSGYQAEESNEITCT-GGKWS-TPPQCK 910
Cdd:cd00033      1 CPPPPVPENGTV-TGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTCE 57
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 390-654 7.85e-09

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 58.56  E-value: 7.85e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  390 VPKCIKEMCESFRVVNGYPESSAARYQVGDKGRYSCYQGYSTpegmSSGEIECLKNGWSVQPTCIKICTKPVLHHGHYsD 469
Cdd:PHA02954    13 LPAVVYSTCTVPTMNNAKLTSTETSFNDKQKVTFTCDSGYYS----LDPNAVCETDKWKYENPCKKMCTVSDYVSELY-D 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  470 KPVFMAGDILQYECDEGymtsdrniIERLKCTE----SGWTKTPECIAITCSvDDEIPNGVSTPQKEEYENGHVLKFSCN 545
Cdd:PHA02954    88 KPLYEVNSTITLICKDE--------TKYFRCEEkngnTSWNDTVTCPNAECQ-PLQLEHGSCQPVKEKYSFGEHITINCD 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  546 ENYKIKGEELRQCYYFGWfpKTLPQCIEiTCKRPSRKGALLSPhlQIYKHLDTVNISCEDGYKINGSDLIQCYSFGWYPK 625
Cdd:PHA02954   159 VGYEVIGASYISCTANSW--NVIPSCQQ-KCDIPSLSNGLISG--STFSIGGVIHLSCKSGFTLTGSPSSTCIDGKWNPV 233

                          250       260
                   ....*....|....*....|....*....
gi 1717019477  626 PPTCQEVGDEEENTNGTVDENHGVKKPSK 654
Cdd:PHA02954   234 LPICVRSNEEFDPVDDGPDDETDLSKLSK 262
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 855-909 1.36e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.14  E-value: 1.36e-08
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477   855 CKQPPTINNGKAaTPLKPSYSDGDTVIYNCDSGYQAEESNEITCT-GGKWS-TPPQC 909
Cdd:smart00032    1 CPPPPDIENGTV-TSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 795-850 1.85e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 51.69  E-value: 1.85e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1717019477  795 CKQPPTINNGKAaTPLKPSYSDGDIVIYNCDSGYQAEESNEITCT-GGKWS-TPPQCK 850
Cdd:cd00033      1 CPPPPVPENGTV-TGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTCE 57
PHA02831 PHA02831
EEV host range protein; Provisional
 685-838 1.98e-08

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 56.92  E-value: 1.98e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  685 NAETVPSKDYYNGDTVKYICNENCQlqgKEEIECKNEKWTSPPRCIKSTeKCPYPPELHNTVEQNLKDHFNENDTVHFKC 764
Cdd:PHA02831    31 NVDSYENKVYEENENLEYKCNNNFD---KVFVTCNNGSWSTKNMCIGKR-NCKDPVTILNGYIKNKKDQYSFGDSVTYAC 106

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1717019477  765 H----ETFILHGSESIQCRKGSWTSPPQCIETQVCKQpPTINNGKAATpLKPSYSDGDIVIYNCDSGYQAEESNEITC 838
Cdd:PHA02831   107 KvnklEKYSIVGNETVKCINKQWVPKYPVCKLIRCKY-PALQNGFLNV-FEKKFYYGDIVNFKCKKGFILLGSSVSTC 182
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 795-849 3.73e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.99  E-value: 3.73e-08
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477   795 CKQPPTINNGKAaTPLKPSYSDGDIVIYNCDSGYQAEESNEITCT-GGKWS-TPPQC 849
Cdd:smart00032    1 CPPPPDIENGTV-TSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
855-909 3.92e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 50.96  E-value: 3.92e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477  855 CKQPPTINNGKAaTPLKPSYSDGDTVIYNCDSGYQAEESNEITCTG-GKWS-TPPQC 909
Cdd:pfam00084    1 CPPPPDIPNGKV-SATKNEYNYGASVSYECDPGYRLVGSPTITCQEdGTWSpPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 736-790 8.03e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 50.15  E-value: 8.03e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477  736 CPYPPELHNTVEQNLKDHFNENDTVHFKCHETFILHGSESIQCRK-GSWT-SPPQCI 790
Cdd:cd00033      1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEnGGWSpPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
795-849 9.10e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 49.81  E-value: 9.10e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477  795 CKQPPTINNGKAaTPLKPSYSDGDIVIYNCDSGYQAEESNEITCTG-GKWS-TPPQC 849
Cdd:pfam00084    1 CPPPPDIPNGKV-SATKNEYNYGASVSYECDPGYRLVGSPTITCQEdGTWSpPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 146-208 1.25e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.38  E-value: 1.25e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1717019477  146 CLPVQPPQNGRIVMTSisdvdEEYPYGYILLFECDsPNYKLSGPNELYCMKSGEWSADVPACE 208
Cdd:cd00033      1 CPPPPVPENGTVTGSK-----GSYSYGSTVTYSCN-EGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 916-970 2.09e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 48.68  E-value: 2.09e-07
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477   916 CDQPPSISNGAIQGSElRKYKAGQSVTYRCINYYVMDGSPTVTCL-QGRWS-QPPTC 970
Cdd:smart00032    1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 692-794 2.18e-07

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 53.84  E-value: 2.18e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  692 KDYYN-GDTVKYICN----ENCQLQGKEEIECKNEKWTsPPRCIKSTEKCPYPPeLHNTVEQNLKDHFNENDTVHFKCHE 766
Cdd:PHA02831    93 KDQYSfGDSVTYACKvnklEKYSIVGNETVKCINKQWV-PKYPVCKLIRCKYPA-LQNGFLNVFEKKFYYGDIVNFKCKK 170

                           90       100       110
                   ....*....|....*....|....*....|
gi 1717019477  767 TFILHGSESIQCRKGSWTSP--PQCIETQV 794
Cdd:PHA02831   171 GFILLGSSVSTCDINSIWYPgiPKCVKDKV 200
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 1107-1162 2.73e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 48.61  E-value: 2.73e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1717019477 1107 CGPPLAIENGGISGTSiSDYVHGSSVEYRCARYYKLKDPKPVVCN-DGEWSN-PPECV 1162
Cdd:cd00033      1 CPPPPVPENGTVTGSK-GSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPpPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 736-789 5.06e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 47.91  E-value: 5.06e-07
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 1717019477   736 CPYPPELHNTVEQNLKDHFNENDTVHFKCHETFILHGSESIQCRK-GSWT-SPPQC 789
Cdd:smart00032    1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLEnGTWSpPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 808-1162 5.53e-07

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 52.35  E-value: 5.53e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  808 TPLKPSYSDGDIVIYNCDSGYQAEESNEI--TCTGGKWSTPPQCKETQvCKQPPTINNGKaatpLKPSYSD-GDTVIYNC 884
Cdd:PHA02927    38 TDANANYNIGDTIEYLCLPGYRKQKMGPIyaKCTGTGWTLFNQCIKRR-CPSPRDIDNGQ----LDIGGVDfGSSITYSC 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  885 DSGYQ----AEESNEITCTGGKWSTP--PQCKEAlaTCDQPPSISNGAIQGSElRKYKAGQSVTYRCINYYVMDGSPTVT 958
Cdd:PHA02927   113 NSGYQligeSKSYCELGSTGSMVWNPeaPICESV--KCQSPPSISNGRHNGYE-DFYTDGSVVTYSCNSGYSLIGNSGVL 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  959 CLQGRWSQPPTCfepctasdeemktnniqlrwlddeklyvqhghrveftckynyvvlppsqefrltcirghldypkcikh 1038
Cdd:PHA02927   190 CSGGEWSDPPTC-------------------------------------------------------------------- 201

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477 1039 gscmvslvelvknnlelgkeytevlhgsfitfkcktgfspvprqnMKMKChdtrltypkctsstpskscgPPLAIENGGI 1118
Cdd:PHA02927   202 ---------------------------------------------QIVKC--------------------PHPTISNGYL 216

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 1717019477 1119 SGTSISDYVHGSSVEYRCARYYKLKDPKPVVCNDGEWSNP--PECV 1162
Cdd:PHA02927   217 SSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPelPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 85-142 6.87e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 47.46  E-value: 6.87e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1717019477   85 CGHPGDLLYGSFDLTRGTdFVFGSRVEYQCDDGYQMISrVNYRECTATG-WNNYVPQCE 142
Cdd:cd00033      1 CPPPPVPENGTVTGSKGS-YSYGSTVTYSCNEGYTLVG-SSTITCTENGgWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
916-970 7.64e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.11  E-value: 7.64e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477  916 CDQPPSISNGAIQGSELRkYKAGQSVTYRCINYYVMDGSPTVTCLQ-GRWSQP-PTC 970
Cdd:pfam00084    1 CPPPPDIPNGKVSATKNE-YNYGASVSYECDPGYRLVGSPTITCQEdGTWSPPfPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 85-141 8.94e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 47.14  E-value: 8.94e-07
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 1717019477    85 CGHPGDLLYGSFDLTRGTdFVFGSRVEYQCDDGYQMISRvNYRECTATG-WNNYVPQC 141
Cdd:smart00032    1 CPPPPDIENGTVTSSSGT-YSYGDTVTYSCDPGYTLIGS-STITCLENGtWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 1107-1161 1.78e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 46.37  E-value: 1.78e-06
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477  1107 CGPPLAIENGGISGTSiSDYVHGSSVEYRCARYYKLKDPKPVVC-NDGEWSNP-PEC 1161
Cdd:smart00032    1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSPPpPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
85-141 2.41e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.95  E-value: 2.41e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1717019477   85 CGHPGDLLYGSFDLTRGtDFVFGSRVEYQCDDGYQMISRvNYRECTATG-WNNYVPQC 141
Cdd:pfam00084    1 CPPPPDIPNGKVSATKN-EYNYGASVSYECDPGYRLVGS-PTITCQEDGtWSPPFPEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 476-629 4.16e-06

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 50.05  E-value: 4.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  476 GDILQYECDEGY-MTSDRNIIERLKCTESGWT-KTPECIAITCSVDDEIPNGVSTPQKEEYENGHVLKFSCNEN----YK 549
Cdd:PHA02639    43 GKLIEYTCNTDYaLIGDRFRTCIKDKNNAIWSnKAPFCMLKECNDPPSIINGKIYNKREMYKVGDEIYYVCNEHkgvqYS 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  550 IKGEELRQCYYFGWFPKTLPQCIEITCKRPSRKGALLS--PHLQIYKHLDTVNISCEDGYKINGSDLIQC-YSFGWYPKP 626
Cdd:PHA02639   123 LVGNEKITCIQDKSWKPDPPICKMINCRFPALQNGYINgiPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCnINATWFPSI 202


                   ...
gi 1717019477  627 PTC 629
Cdd:PHA02639   203 PTC 205
PHA02639 PHA02639
EEV host range protein; Provisional
 212-395 4.16e-06

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 50.05  E-value: 4.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  212 CQEPSIPNGKMMSRLPRKmqYENKERIQYECDPGYKHESRGYSECIENG----W-NPAPSCIEIVCSFQ-NVVNGNLQPE 285
Cdd:PHA02639    22 CDKPDDISNGFITELMEK--YEIGKLIEYTCNTDYALIGDRFRTCIKDKnnaiWsNKAPFCMLKECNDPpSIINGKIYNK 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  286 KNVYRENERVNLICNKGYQPEYK---DEFPKCTK-TGWS-SPLLCVHKDCSFPEIENGRLlqTQYSTYKNYYFPMRKGrk 360
Cdd:PHA02639   100 REMYKVGDEIYYVCNEHKGVQYSlvgNEKITCIQdKSWKpDPPICKMINCRFPALQNGYI--NGIPSNKKFYYKTRVG-- 175

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1717019477  361 idYICTEGF-FTEEGNSWGGIECTdegWSP-VPKCIK 395
Cdd:PHA02639   176 --FSCKSGFdLVGEKYSTCNINAT---WFPsIPTCVR 207
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 146-207 4.65e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 44.82  E-value: 4.65e-06
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1717019477   146 CLPVQPPQNGRIVMTSisdvdEEYPYGYILLFECDsPNYKLSGPNELYCMKSGEWSADVPAC 207
Cdd:smart00032    1 CPPPPDIENGTVTSSS-----GTYSYGDTVTYSCD-PGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 511-629 5.19e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 49.17  E-value: 5.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  511 CIAITCSVDDEIPNGVSTPQKEEYENGHVLKFSCNEN-----YKIKGEELRQCYYFGWFPKTLPQCIEITCKRPSRKGAL 585
Cdd:PHA02817    19 CDLNKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCKIIRCRFPALQNGF 98

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1717019477  586 LS--PHLQIYKHLDTVNISCEDGYKINGSDLIQC-YSFGWYPKPPTC 629
Cdd:PHA02817    99 VNgiPDSKKFYYESEVSFSCKPGFVLIGTKYSVCgINSSWIPKVPIC 145
Sushi pfam00084
Sushi repeat (SCR repeat);
146-207 5.43e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 44.80  E-value: 5.43e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1717019477  146 CLPVQPPQNGRIVMTsisdvDEEYPYGYILLFECDsPNYKLSGPNELYCMKSGEWSADVPAC 207
Cdd:pfam00084    1 CPPPPDIPNGKVSAT-----KNEYNYGASVSYECD-PGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 677-730 6.31e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 44.76  E-value: 6.31e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477  677 CPPAPQLENAETVPSKDYYN-GDTVKYICNENCQLQGKEEIEC-KNEKWT-SPPRCI 730
Cdd:cd00033      1 CPPPPVPENGTVTGSKGSYSyGSTVTYSCNEGYTLVGSSTITCtENGGWSpPPPTCE 57
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 265-490 1.12e-05

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 48.93  E-value: 1.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  265 PSCIEIVCSFQNVVNGNLQPEKNVYRENERVNLICNKGYQPEYKDEFPKCTKTGWSSPL--LCVHKDcSFPEIENGRLLQ 342
Cdd:PHA02954    14 PAVVYSTCTVPTMNNAKLTSTETSFNDKQKVTFTCDSGYYSLDPNAVCETDKWKYENPCkkMCTVSD-YVSELYDKPLYE 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  343 TQYStyknyyfpmrkgrkIDYIC---TEGFFTEEGNSwggiectDEGWSPVPKCIKEMCESFRVVNGYPESSAARYQVGD 419
Cdd:PHA02954    93 VNST--------------ITLICkdeTKYFRCEEKNG-------NTSWNDTVTCPNAECQPLQLEHGSCQPVKEKYSFGE 151

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1717019477  420 KGRYSCYQGYstpEGMSSGEIECLKNGWSVQPTCIKICTKPVLHHGHYSDKpVFMAGDILQYECDEGYMTS 490
Cdd:PHA02954   152 HITINCDVGY---EVIGASYISCTANSWNVIPSCQQKCDIPSLSNGLISGS-TFSIGGVIHLSCKSGFTLT 218
PHA02639 PHA02639
EEV host range protein; Provisional
 851-970 1.31e-05

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 48.51  E-value: 1.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  851 ETQVCKQPPTINNGkAATPLKPSYSDGDTVIYNCDSGYQAEESNEITCTGGK----WST-PPQCkeALATCDQPPSISNG 925
Cdd:PHA02639    18 KSIYCDKPDDISNG-FITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKnnaiWSNkAPFC--MLKECNDPPSIING 94

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1717019477  926 AIQgSELRKYKAGQSVTYRCINY----YVMDGSPTVTCLQGR-WS-QPPTC 970
Cdd:PHA02639    95 KIY-NKREMYKVGDEIYYVCNEHkgvqYSLVGNEKITCIQDKsWKpDPPIC 144
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 677-729 1.56e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 43.67  E-value: 1.56e-05
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 1717019477   677 CPPAPQLENAETVPSKDYYN-GDTVKYICNENCQLQGKEEIEC-KNEKWT-SPPRC 729
Cdd:smart00032    1 CPPPPDIENGTVTSSSGTYSyGDTVTYSCDPGYTLIGSSTITClENGTWSpPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 513-632 2.18e-05

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 47.74  E-value: 2.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  513 AITCSVDDEIPNGVSTPQKEEYENGHVLKFSCNENYKIKGEELRQCYYFG----WFPKTlPQCIEITCKR-PSRKGALLS 587
Cdd:PHA02639    19 SIYCDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKnnaiWSNKA-PFCMLKECNDpPSIINGKIY 97

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 1717019477  588 PHLQIYKHLDTVNISCED----GYKINGSDLIQC-YSFGWYPKPPTCQEV 632
Cdd:PHA02639    98 NKREMYKVGDEIYYVCNEhkgvQYSLVGNEKITCiQDKSWKPDPPICKMI 147
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 516-571 3.09e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.51  E-value: 3.09e-05
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 1717019477   516 CSVDDEIPNGVSTPQKEEYENGHVLKFSCNENYKIKGEELRQCYYFGWFPKTLPQC 571
Cdd:smart00032    1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
1107-1161 3.58e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.49  E-value: 3.58e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477 1107 CGPPLAIENGGISGTSiSDYVHGSSVEYRCARYYKLKDPKPVVC-NDGEWSNP-PEC 1161
Cdd:pfam00084    1 CPPPPDIPNGKVSATK-NEYNYGASVSYECDPGYRLVGSPTITCqEDGTWSPPfPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
677-729 5.52e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.10  E-value: 5.52e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1717019477  677 CPPAPQLENAETVPSKDYYN-GDTVKYICNENCQLQGKEEIEC-KNEKWTSP-PRC 729
Cdd:pfam00084    1 CPPPPDIPNGKVSATKNEYNyGASVSYECDPGYRLVGSPTITCqEDGTWSPPfPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
736-789 5.57e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.10  E-value: 5.57e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1717019477  736 CPYPPELHNTVEQNLKDHFNENDTVHFKCHETFILHGSESIQCRK-GSWTSP-PQC 789
Cdd:pfam00084    1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEdGTWSPPfPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 579-630 1.23e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 40.91  E-value: 1.23e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1717019477  579 PSRKGALLSPHLQIYKHLDTVNISCEDGYKINGSDLIQCYSFG-WYPKPPTCQ 630
Cdd:cd00033      5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGgWSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 516-572 2.19e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 40.14  E-value: 2.19e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1717019477  516 CSVDDEIPNGVSTPQKEEYENGHVLKFSCNENYKIKGEELRQCYYFG-WFPkTLPQCI 572
Cdd:cd00033      1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGgWSP-PPPTCE 57
PHA02831 PHA02831
EEV host range protein; Provisional
 285-429 4.21e-04

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 43.83  E-value: 4.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  285 EKNVYRENERVNLICNKGYQpeykDEFPKCTKTGWSSPLLCVHK-DCSFP-EIENGRL--LQTQYSTyknyyfpmrkGRK 360
Cdd:PHA02831    36 ENKVYEENENLEYKCNNNFD----KVFVTCNNGSWSTKNMCIGKrNCKDPvTILNGYIknKKDQYSF----------GDS 101

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1717019477  361 IDYICTEG---FFTEEGNSwgGIECTDEGWSP-VPKCIKEMCESFRVVNGYPESSAARYQVGDKGRYSCYQGY 429
Cdd:PHA02831   102 VTYACKVNkleKYSIVGNE--TVKCINKQWVPkYPVCKLIRCKYPALQNGFLNVFEKKFYYGDIVNFKCKKGF 172
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 212-268 4.36e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 39.37  E-value: 4.36e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  212 CQEPSIP-NGKMMSRLPRkmqYENKERIQYECDPGYKHESRGYSECIENG-WNP-APSCI 268
Cdd:cd00033      1 CPPPPVPeNGTVTGSKGS---YSYGSTVTYSCNEGYTLVGSSTITCTENGgWSPpPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 215-267 6.79e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 39.05  E-value: 6.79e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*
gi 1717019477   215 PSIPNGKMMSRLPRkmqYENKERIQYECDPGYKHESRGYSECIENG-WNP-APSC 267
Cdd:smart00032    5 PDIENGTVTSSSGT---YSYGDTVTYSCDPGYTLIGSSTITCLENGtWSPpPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 873-1076 8.36e-04

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 42.67  E-value: 8.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  873 SYSDGDTVIYNCDSGYqaeESNEITCTGGKWSTPPQCKeALATCDQPPSISNGAIQGSElRKYKAGQSVTYRC----INY 948
Cdd:PHA02831    39 VYEENENLEYKCNNNF---DKVFVTCNNGSWSTKNMCI-GKRNCKDPVTILNGYIKNKK-DQYSFGDSVTYACkvnkLEK 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  949 YVMDGSPTVTCLQGRW-SQPPTCfepctasdeemktnniqlrwlddeKLyvqhghrveFTCKYnyvvlPPSQEFRLTCIR 1027
Cdd:PHA02831   114 YSIVGNETVKCINKQWvPKYPVC------------------------KL---------IRCKY-----PALQNGFLNVFE 155

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1717019477 1028 GHLDYpkcikhgscmvslvelvknnlelgkeytevlhGSFITFKCKTGF 1076
Cdd:PHA02831   156 KKFYY--------------------------------GDIVNFKCKKGF 172
Sushi pfam00084
Sushi repeat (SCR repeat);
516-571 8.42e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 38.63  E-value: 8.42e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1717019477  516 CSVDDEIPNGVSTPQKEEYENGHVLKFSCNENYKIKGEELRQCYYFGWFPKTLPQC 571
Cdd:pfam00084    1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 692-838 1.01e-03

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 42.73  E-value: 1.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  692 KDYYNGDTVKYICNENCQLQGKEEIECKNEK----WTS-PPRCIksTEKCPYPPELHNTVEQNLKDHFNENDTVHFKCHE 766
Cdd:PHA02639    38 EKYEIGKLIEYTCNTDYALIGDRFRTCIKDKnnaiWSNkAPFCM--LKECNDPPSIINGKIYNKREMYKVGDEIYYVCNE 115

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1717019477  767 ----TFILHGSESIQCRKG-SWTSPPQCIETQVCKQPPTINNGKAATPLKPSYSDGDIVIYNCDSGYQAEESNEITC 838
Cdd:PHA02639   116 hkgvQYSLVGNEKITCIQDkSWKPDPPICKMINCRFPALQNGYINGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTC 192
PHA02831 PHA02831
EEV host range protein; Provisional
 232-396 1.02e-03

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 42.29  E-value: 1.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  232 YENKERIQYECDPGYkheSRGYSECIENGWNPAPSCI-EIVCSFQ-NVVNGNLQPEKNVYRENERVNLICNKGYQPEYK- 308
Cdd:PHA02831    40 YEENENLEYKCNNNF---DKVFVTCNNGSWSTKNMCIgKRNCKDPvTILNGYIKNKKDQYSFGDSVTYACKVNKLEKYSi 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  309 --DEFPKCTKTGW--SSPlLCVHKDCSFPEIENGRLlqtqYSTYKNYYFpmrkGRKIDYICTEGF-FTEEGNSWGGIECT 383
Cdd:PHA02831   117 vgNETVKCINKQWvpKYP-VCKLIRCKYPALQNGFL----NVFEKKFYY----GDIVNFKCKKGFiLLGSSVSTCDINSI 187

                          170
                   ....*....|....
gi 1717019477  384 degWSP-VPKCIKE 396
Cdd:PHA02831   188 ---WYPgIPKCVKD 198
PHA02817 PHA02817
EEV Host range protein; Provisional
 676-791 1.07e-03

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 41.85  E-value: 1.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  676 KCPPAPQLENAETVPSKDYYN-GDTVKYICNENCQ-----LQGKEEIEC-KNEKWT-SPPRCikSTEKCPYPPeLHNTVE 747
Cdd:PHA02817    23 KCCYPPSIKNGYIYNKKTEYNiGSNVTFFCGNNTRgvrytLVGEKNIICeKDGKWNkEFPVC--KIIRCRFPA-LQNGFV 99

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 1717019477  748 QNLKDH--FNENDTVHFKCHETFILHGSESIQCRKGSWTSP--PQCIE 791
Cdd:PHA02817   100 NGIPDSkkFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPkvPICSR 147
PHA02639 PHA02639
EEV host range protein; Provisional
 403-572 1.11e-03

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 42.34  E-value: 1.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  403 VVNGYPESSAARYQVGDKGRYSCYQGYSTPEGMSSGEIECLKNG-WSVQ-PTC-IKICTKP--VLHHGHYSDKPVFMAGD 477
Cdd:PHA02639    28 ISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAiWSNKaPFCmLKECNDPpsIINGKIYNKREMYKVGD 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  478 ILQYECDEgYMTSDRNII--ERLKCTE-SGWTKTPE-CIAITC---SVDDEIPNGVSTPQKEEYENGhvLKFSCNENYKI 550
Cdd:PHA02639   108 EIYYVCNE-HKGVQYSLVgnEKITCIQdKSWKPDPPiCKMINCrfpALQNGYINGIPSNKKFYYKTR--VGFSCKSGFDL 184

                          170       180
                   ....*....|....*....|...
gi 1717019477  551 KGEELRQCYYFG-WFPkTLPQCI 572
Cdd:PHA02639   185 VGEKYSTCNINAtWFP-SIPTCV 206
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 22-81 1.24e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 38.21  E-value: 1.24e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1717019477   22 CGPPDSIPIAELVGEwdKESYPHGTEATYLCRPGYIKVGRILWKCL-NGEWKevNPMVKCR 81
Cdd:cd00033      1 CPPPPVPENGTVTGS--KGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWS--PPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 576-629 1.76e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 37.89  E-value: 1.76e-03
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 1717019477   576 CKRPSR-KGALLSPHLQIYKHLDTVNISCEDGYKINGSDLIQCYSFG-WYPKPPTC 629
Cdd:smart00032    1 CPPPPDiENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGtWSPPPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 109-285 2.45e-03

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 41.13  E-value: 2.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  109 RVEYQCDDGYQMIsrvnYRECTATGWNNYVPQCEVRKCL-PVQppqngrIVMTSISDVDEEYPYGYILLFECDS---PNY 184
Cdd:PHA02831    45 NLEYKCNNNFDKV----FVTCNNGSWSTKNMCIGKRNCKdPVT------ILNGYIKNKKDQYSFGDSVTYACKVnklEKY 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  185 KLSGPNELYCMkSGEWSADVPACEVISCQEPSIPNGkMMSRLPRKMQYenKERIQYECDPGYKHESRGYSEC-IENGWNP 263
Cdd:PHA02831   115 SIVGNETVKCI-NKQWVPKYPVCKLIRCKYPALQNG-FLNVFEKKFYY--GDIVNFKCKKGFILLGSSVSTCdINSIWYP 190

                          170       180
                   ....*....|....*....|...
gi 1717019477  264 A-PSCIeivcsfQNVVNGNLQPE 285
Cdd:PHA02831   191 GiPKCV------KDKVHNEIQPN 207
Sushi pfam00084
Sushi repeat (SCR repeat);
215-267 2.54e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 37.09  E-value: 2.54e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1717019477  215 PSIPNGKMMSRLPrkmQYENKERIQYECDPGYKHESRGYSECIENG-WNPA-PSC 267
Cdd:pfam00084    5 PDIPNGKVSATKN---EYNYGASVSYECDPGYRLVGSPTITCQEDGtWSPPfPEC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 855-959 2.55e-03

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 40.69  E-value: 2.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477  855 CKQPPTINNGKAATPlKPSYSDGDTVIYNCDSG-----YQAEESNEITCT-GGKWST-PPQCKeaLATCdQPPSISNGAI 927
Cdd:PHA02817    24 CCYPPSIKNGYIYNK-KTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEkDGKWNKeFPVCK--IIRC-RFPALQNGFV 99

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1717019477  928 QG-SELRKYKAGQSVTYRCINYYVMDGSPTVTC 959
Cdd:PHA02817   100 NGiPDSKKFYYESEVSFSCKPGFVLIGTKYSVC 132
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 403-454 2.75e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 37.06  E-value: 2.75e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1717019477  403 VVNGYPESSAARYQVGDKGRYSCYQGYsTPEGmsSGEIECLKNG-WS-VQPTCI 454
Cdd:cd00033      7 PENGTVTGSKGSYSYGSTVTYSCNEGY-TLVG--SSTITCTENGgWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 22-80 5.53e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 36.35  E-value: 5.53e-03
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717019477    22 CGPPDSIPIAELVGEwdKESYPHGTEATYLCRPGYIKVGRILWKCL-NGEWKevNPMVKC 80
Cdd:smart00032    1 CPPPPDIENGTVTSS--SGTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWS--PPPPTC 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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