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Conserved domains on  [gi|1663456094|ref|XP_029139716|]
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bromo adjacent homology domain-containing 1 protein [Protobothrops mucrosquamatus]

Protein Classification

BAH_BAHCC1 domain-containing protein( domain architecture ID 10140545)

BAH_BAHCC1 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BAH_BAHCC1 cd04714
BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. ...
 682-787 1.06e-52

BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


:

Pssm-ID: 240065  Cd Length: 121  Bit Score: 179.13  E-value: 1.06e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1663456094 682 GEIIRVRDTVLLKSGPRKKsMPYVAKISALWEDPkTGELMMSLLWYYRPEHTQGGRNSSMHQNEIFASRHQDENSVACIE 761
Cdd:cd04714     1 KEIIRVGDCVLFKSPGRPS-LPYVARIESLWEDP-EGNMVVRVKWYYRPEETKGGRKPNHGEKELFASDHQDENSVQTIE 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1663456094 762 EKCYVLTFAEY---------------CRFCALAKRRVEGIP 787
Cdd:cd04714    79 HKCYVLTFAEYerlarvkkkpqdgvdFYYCAGTYNPDTGML 119
 
Name Accession Description Interval E-value
BAH_BAHCC1 cd04714
BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. ...
 682-787 1.06e-52

BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240065  Cd Length: 121  Bit Score: 179.13  E-value: 1.06e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1663456094 682 GEIIRVRDTVLLKSGPRKKsMPYVAKISALWEDPkTGELMMSLLWYYRPEHTQGGRNSSMHQNEIFASRHQDENSVACIE 761
Cdd:cd04714     1 KEIIRVGDCVLFKSPGRPS-LPYVARIESLWEDP-EGNMVVRVKWYYRPEETKGGRKPNHGEKELFASDHQDENSVQTIE 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1663456094 762 EKCYVLTFAEY---------------CRFCALAKRRVEGIP 787
Cdd:cd04714    79 HKCYVLTFAEYerlarvkkkpqdgvdFYYCAGTYNPDTGML 119
BAH pfam01426
BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been ...
 683-835 8.16e-18

BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been called ELM1 and BAM (Bromo adjacent motif) domain. The function of this domain is unknown but may be involved in protein-protein interaction.


Pssm-ID: 460207  Cd Length: 120  Bit Score: 80.04  E-value: 8.16e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1663456094 683 EIIRVRDTVLLKSGPRKKsMPYVAKISALWEDPKTGELMMSLLWYYRPEHTQGGRNSSMHQNEIFASRHQDENSVACIEE 762
Cdd:pfam01426   1 ETYSVGDFVLVEPDDADE-PYYVARIEELFEDTKNGKKMVRVQWFYRPEETVHRAGKAFNKDELFLSDEEDDVPLSAIIG 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1663456094 763 KCYVLTFAEYCRFCalakrrvegipgkkavmvppseeystpahrkvPEDTDPELVFLCRHVYDFRHGRILKNP 835
Cdd:pfam01426  80 KCSVLHKSDLESLD--------------------------------PYKIKEPDDFFCELLYDPKTKSFKKLP 120
BAH smart00439
Bromo adjacent homology domain;
684-774 6.50e-17

Bromo adjacent homology domain;


Pssm-ID: 214664 [Multi-domain]  Cd Length: 121  Bit Score: 77.33  E-value: 6.50e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1663456094  684 IIRVRDTVLLKSGPRKKSmPYVAKISALWEDPKTGELMMSLL-WYYRPEHTQGGRNSSMHQNEIFASRHQDENSVACIEE 762
Cdd:smart00439   1 TISVGDFVLVEPDDADEP-YYIGRIEEIFETKKNSESKMVRVrWFYRPEETVLEKAALFDKNEVFLSDEYDTVPLSDIIG 79

                           90
                   ....*....|..
gi 1663456094  763 KCYVLTFAEYCR 774
Cdd:smart00439  80 KCNVLYKSDYPG 91
 
Name Accession Description Interval E-value
BAH_BAHCC1 cd04714
BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. ...
 682-787 1.06e-52

BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240065  Cd Length: 121  Bit Score: 179.13  E-value: 1.06e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1663456094 682 GEIIRVRDTVLLKSGPRKKsMPYVAKISALWEDPkTGELMMSLLWYYRPEHTQGGRNSSMHQNEIFASRHQDENSVACIE 761
Cdd:cd04714     1 KEIIRVGDCVLFKSPGRPS-LPYVARIESLWEDP-EGNMVVRVKWYYRPEETKGGRKPNHGEKELFASDHQDENSVQTIE 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1663456094 762 EKCYVLTFAEY---------------CRFCALAKRRVEGIP 787
Cdd:cd04714    79 HKCYVLTFAEYerlarvkkkpqdgvdFYYCAGTYNPDTGML 119
BAH cd04370
BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). ...
 682-782 9.51e-19

BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in mammalian DNA methyltransferases and the MTA1 subunits of histone deacetylase complexes. A BAH domain is also found in Yeast Sir3p and in the origin receptor complex protein 1 (Orc1p), where it was found to interact with the N-terminal lobe of the silence information regulator 1 protein (Sir1p), confirming the initial hypothesis that BAH plays a role in protein-protein interactions.


Pssm-ID: 239835 [Multi-domain]  Cd Length: 123  Bit Score: 82.82  E-value: 9.51e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1663456094 682 GEIIRVRDTVLLKSGPRKKSM-PYVAKISALWEDPKtGELMMSLLWYYRPEHTQGGRNSSMHQNEIFASRHQDENSVACI 760
Cdd:cd04370     1 GITYEVGDSVYVEPDDSIKSDpPYIARIEELWEDTN-GSKQVKVRWFYRPEETPKGLSPFALRRELFLSDHLDEIPVESI 79

                          90       100
                  ....*....|....*....|..
gi 1663456094 761 EEKCYVLTFAEYCRFCALAKRR 782
Cdd:cd04370    80 IGKCKVLFVSEFEGLKQRPNKI 101
BAH pfam01426
BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been ...
 683-835 8.16e-18

BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been called ELM1 and BAM (Bromo adjacent motif) domain. The function of this domain is unknown but may be involved in protein-protein interaction.


Pssm-ID: 460207  Cd Length: 120  Bit Score: 80.04  E-value: 8.16e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1663456094 683 EIIRVRDTVLLKSGPRKKsMPYVAKISALWEDPKTGELMMSLLWYYRPEHTQGGRNSSMHQNEIFASRHQDENSVACIEE 762
Cdd:pfam01426   1 ETYSVGDFVLVEPDDADE-PYYVARIEELFEDTKNGKKMVRVQWFYRPEETVHRAGKAFNKDELFLSDEEDDVPLSAIIG 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1663456094 763 KCYVLTFAEYCRFCalakrrvegipgkkavmvppseeystpahrkvPEDTDPELVFLCRHVYDFRHGRILKNP 835
Cdd:pfam01426  80 KCSVLHKSDLESLD--------------------------------PYKIKEPDDFFCELLYDPKTKSFKKLP 120
BAH smart00439
Bromo adjacent homology domain;
684-774 6.50e-17

Bromo adjacent homology domain;


Pssm-ID: 214664 [Multi-domain]  Cd Length: 121  Bit Score: 77.33  E-value: 6.50e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1663456094  684 IIRVRDTVLLKSGPRKKSmPYVAKISALWEDPKTGELMMSLL-WYYRPEHTQGGRNSSMHQNEIFASRHQDENSVACIEE 762
Cdd:smart00439   1 TISVGDFVLVEPDDADEP-YYIGRIEEIFETKKNSESKMVRVrWFYRPEETVLEKAALFDKNEVFLSDEYDTVPLSDIIG 79

                           90
                   ....*....|..
gi 1663456094  763 KCYVLTFAEYCR 774
Cdd:smart00439  80 KCNVLYKSDYPG 91
BAH_polybromo cd04717
BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human ...
 682-774 2.97e-12

BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional regulation. Saccharomyces cerevisiae RSC1 and RSC2 are part of the 15-subunit nucleosome remodeling RSC complex. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240068  Cd Length: 121  Bit Score: 64.14  E-value: 2.97e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1663456094 682 GEIIRVRDTVLLKSgPRKKSMPYVAKISALWEDPKtGELMMSLLWYYRPE---HTQGGRnssMHQNEIFASRHQDENSVA 758
Cdd:cd04717     1 GLQYRVGDCVYVAN-PEDPSKPIIFRIERLWKDED-GEKFFFGCWFYRPEetfHEPTRK---FYKNEVFKSPLYETVPVE 75

                          90
                  ....*....|....*.
gi 1663456094 759 CIEEKCYVLTFAEYCR 774
Cdd:cd04717    76 EIVGKCAVMDVKDYIK 91
BAH_plant_3 cd04713
BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH ...
 672-825 2.29e-11

BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240064  Cd Length: 146  Bit Score: 62.48  E-value: 2.29e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1663456094 672 RKSYQAVERDGEIIRVRDTVLLKsgPRKKSMPYVAKISALWEDPKtGELMMSLLWYYRPEHTQ---GGRNSSMHQNEIFA 748
Cdd:cd04713     8 KCHYTSFEKDGNKYRLEDCVLLV--PEDDQKPYIAIIKDIYKQEE-GSLKLEVQWLYRPEEIEkkkGGNWKAEDPRELFY 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1663456094 749 SRHQDENSVACIEEKCYVltfaeycrfcalakrrvegipgkkavmvppseeYSTPAHRKVPEDTDPElVFLCRHVYD 825
Cdd:cd04713    85 SFHRDEVPAESVLHPCKV---------------------------------AFVPKGKQIPLRKGHS-GFIVRRVYD 127
BAH_Orc1p_like cd04715
BAH, or Bromo Adjacent Homology domain, as present in the Schizosaccharomyces pombe homolog of ...
 673-774 6.59e-08

BAH, or Bromo Adjacent Homology domain, as present in the Schizosaccharomyces pombe homolog of Saccharomyces cerevisiae Orc1p and similar proteins. Orc1 is part of the Yeast Sir1-origin recognition complex, the Orc1p BAH doman functions in epigenetic silencing. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240066  Cd Length: 159  Bit Score: 52.89  E-value: 6.59e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1663456094 673 KSYQAVERDGEIIRVRDTVLLKSGprkKSMPYVAKISALWEDP-KTGELMMSLLWYYRP-----EHTQggrNSSMHQNEI 746
Cdd:cd04715    18 QFYRSFTYDGVEYRLYDDVYVHNG---DSEPYIGKIIKIYETAiDSGKKKVKVIWFFRPseirmELKG---EPKRHINEV 91

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1663456094 747 FASRHQDE-----NSVACIEEKCYVLTFAEYCR 774
Cdd:cd04715    92 FLACGRGEglaniNLLESIIGKCNVVCISEDFR 124
BAH_plant_1 cd04721
BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH ...
 680-787 1.15e-06

BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240072  Cd Length: 130  Bit Score: 48.59  E-value: 1.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1663456094 680 RDGEIIRVRDTVLLKSGPRKKsmpYVAKISALWEDpKTGELMMSLLWYYRPEHTQG-GRNSSMHQNEIFASRHQDENSVA 758
Cdd:cd04721     3 RNGVTISVHDFVYVLSEEEDR---YVAYIEDLYED-KKGSKMVKVRWFHTTDEVGAaLSPDSVNPREIFLSPNLQVISVE 78

                          90       100
                  ....*....|....*....|....*....
gi 1663456094 759 CIEEKCYVLTFAEYCRFCALAKRRVEGIP 787
Cdd:cd04721    79 CIDGLATVLTREHYEKFQSVPKNSSELQA 107
BAH_plantDCM_I cd04716
BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5) ...
 682-767 2.84e-06

BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases (DCM) from plants. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG dinucleotide, has profound effects on the genome. These effects include transcriptional repression via inhibition of transcription factor binding, the recruitment of methyl-binding proteins and their associated chromatin remodeling factors, X chromosome inactivation, imprinting, and the suppression of parasitic DNA sequences. DNA methylation is also essential for proper embryonic development and is an important player in both DNA repair and genome stability. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240067  Cd Length: 122  Bit Score: 47.05  E-value: 2.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1663456094 682 GEIIRVRDTVLLKSGPRKKsmPYVAKISALWEDPKtGELMMSLLWYYRPEHTQGGRNSSMHQNE-IFASRHQDENSVACI 760
Cdd:cd04716     1 GITYNLGDDAYVQGGEGEE--PFICKITEFFEGTD-GKTYFTAQWFYRAEDTVIERQATNHDKKrVFYSEIKNDNPLDCL 77


                  ....*..
gi 1663456094 761 EEKCYVL 767
Cdd:cd04716    78 ISKVKIL 84
BAH_Orc1p_Yeast cd04720
BAH, or Bromo Adjacent Homology domain, as present in Orc1p, which again is part of the ...
 672-825 4.49e-04

BAH, or Bromo Adjacent Homology domain, as present in Orc1p, which again is part of the Saccharomyces cerevisiae Sir1-origin recognition complex, and as present in Sir3p. The Orc1p BAH doman functions in epigenetic silencing. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240071  Cd Length: 179  Bit Score: 42.02  E-value: 4.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1663456094 672 RKSYQAVERDGEIIRVRDTVLLKSGPRKKsmPYVAKISALWEDPKTGELMMSLLWYYRPEHTQGGRN---------SSMH 742
Cdd:cd04720    40 RKIFLARDSDGLELSVGDTILVKDDVANS--PSVYLIHEIRLNTLNNEVELWVMWFLRWFEINPARYykqfdpefrSESN 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1663456094 743 QNEIFASRHQDENSVACIEEKCYVLTFAEYcrfcalakrrvegipgkkavmvppseeystpaHRKVPEDTDPELVFLCRH 822
Cdd:cd04720   118 KNELYLTAELSEIKLKDIIDKANVLSESEF--------------------------------NDLSTDDKNGERTFFCRY 165


                  ...
gi 1663456094 823 VYD 825
Cdd:cd04720   166 ACE 168
BAH_MTA cd04709
BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The ...
 686-771 3.16e-03

BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240060  Cd Length: 164  Bit Score: 39.30  E-value: 3.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1663456094 686 RVRDTVLLKSGPrkkSMPYV-AKISALwEDPKTGELMMSLLWYYR----PEH-------------TQGGR-----NSSMH 742
Cdd:cd04709     5 RVGDYVYFESSP---NNPYLiRRIEEL-NKTARGHVEAKVVCYYRrrdiPDSlyqladqhrreleEKSDDltpkqRHQLR 80

                          90       100
                  ....*....|....*....|....*....
gi 1663456094 743 QNEIFASRHQDENSVACIEEKCYVLTFAE 771
Cdd:cd04709    81 HRELFLSRQVETLPATHIRGKCSVTLLND 109
BAH_Dnmt1_I cd04760
BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5) ...
 682-767 4.25e-03

BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG dinucleotide, has profound effects on the genome. These effects include transcriptional repression via inhibition of transcription factor binding, the recruitment of methyl-binding proteins and their associated chromatin remodeling factors, X chromosome inactivation, imprinting, and the suppression of parasitic DNA sequences. DNA methylation is also essential for proper embryonic development and is an important player in both DNA repair and genome stability. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240107  Cd Length: 124  Bit Score: 38.21  E-value: 4.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1663456094 682 GEIIRVRDTVLLKsgPRKKSMP-YVAKISALWEDpKTGELMMSLLWYYRPEHTQGGRNSSmhQNEIFASRHQDENSVACI 760
Cdd:cd04760     1 GEELEAGDCVSVK--PDDPTKPlYIARVTYMWKD-SIGGKMFHAHWFCRGSDTVLGETSD--PLELFLVDECEDMALSSI 75


                  ....*..
gi 1663456094 761 EEKCYVL 767
Cdd:cd04760    76 HGKVNVI 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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