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Conserved domains on  [gi|1585793756|ref|XP_028091255|]
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caffeoylshikimate esterase-like [Camellia sinensis]

Protein Classification

alpha/beta hydrolase family protein( domain architecture ID 229394)

alpha/beta hydrolase family protein may catalyze the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Abhydrolase super family cl21494
alpha/beta hydrolases; A functionally diverse superfamily containing proteases, lipases, ...
 27-340 1.39e-100

alpha/beta hydrolases; A functionally diverse superfamily containing proteases, lipases, peroxidases, esterases, epoxide hydrolases and dehalogenases. The catalytic apparatus typically involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine, and often the mechanism involves a nucleophilic attack on a carbonyl carbon atom.


The actual alignment was detected with superfamily member PLN02298:

Pssm-ID: 473884 [Multi-domain]  Cd Length: 330  Bit Score: 299.77  E-value: 1.39e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  27 PFGDLTREDFYNKHQILHQESFMLNKQNIKIFTQSWLPSSAPRLRGLIAVIHGYTDESSWLIQLTAIAIAKAGFYVCALD 106
Cdd:PLN02298   15 FWGETPEEEYYALKGIKGSKSFFTSPRGLSLFTRSWLPSSSSPPRALIFMVHGYGNDISWTFQSTAIFLAQMGFACFALD 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 107 LQGHGNSDGVRGHIPDIEPVVEDCVQFFDS--ARASHPKLPAFIFGESLGGAIAILMCLKQRNsEWSGLILNGAMCGVSK 184
Cdd:PLN02298   95 LEGHGRSEGLRAYVPNVDLVVEDCLSFFNSvkQREEFQGLPRFLYGESMGGAICLLIHLANPE-GFDGAVLVAPMCKISD 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 185 KFKPVWPLEQLLPAAAFVAPTWKIAITEDPAKRSYKEEWKRRLVMKSPNRaANGKVTAATALEFLRVCEYIKRNSHGLKI 264
Cdd:PLN02298  174 KIRPPWPIPQILTFVARFLPTLAIVPTADLLEKSVKVPAKKIIAKRNPMR-YNGKPRLGTVVELLRVTDYLGKKLKDVSI 252

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1585793756 265 PLLVVHGGDDKICDPKSARLLYESAASEDKTLKIFTGMWHQFI-GEPNESVEQVFGTILTWIGERADNASETYSNNG 340
Cdd:PLN02298  253 PFIVLHGSADVVTDPDVSRALYEEAKSEDKTIKIYDGMMHSLLfGEPDENIEIVRRDILSWLNERCTGKATPSEDSI 329
 
Name Accession Description Interval E-value
PLN02298 PLN02298
hydrolase, alpha/beta fold family protein
 27-340 1.39e-100

hydrolase, alpha/beta fold family protein


Pssm-ID: 165939 [Multi-domain]  Cd Length: 330  Bit Score: 299.77  E-value: 1.39e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  27 PFGDLTREDFYNKHQILHQESFMLNKQNIKIFTQSWLPSSAPRLRGLIAVIHGYTDESSWLIQLTAIAIAKAGFYVCALD 106
Cdd:PLN02298   15 FWGETPEEEYYALKGIKGSKSFFTSPRGLSLFTRSWLPSSSSPPRALIFMVHGYGNDISWTFQSTAIFLAQMGFACFALD 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 107 LQGHGNSDGVRGHIPDIEPVVEDCVQFFDS--ARASHPKLPAFIFGESLGGAIAILMCLKQRNsEWSGLILNGAMCGVSK 184
Cdd:PLN02298   95 LEGHGRSEGLRAYVPNVDLVVEDCLSFFNSvkQREEFQGLPRFLYGESMGGAICLLIHLANPE-GFDGAVLVAPMCKISD 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 185 KFKPVWPLEQLLPAAAFVAPTWKIAITEDPAKRSYKEEWKRRLVMKSPNRaANGKVTAATALEFLRVCEYIKRNSHGLKI 264
Cdd:PLN02298  174 KIRPPWPIPQILTFVARFLPTLAIVPTADLLEKSVKVPAKKIIAKRNPMR-YNGKPRLGTVVELLRVTDYLGKKLKDVSI 252

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1585793756 265 PLLVVHGGDDKICDPKSARLLYESAASEDKTLKIFTGMWHQFI-GEPNESVEQVFGTILTWIGERADNASETYSNNG 340
Cdd:PLN02298  253 PFIVLHGSADVVTDPDVSRALYEEAKSEDKTIKIYDGMMHSLLfGEPDENIEIVRRDILSWLNERCTGKATPSEDSI 329
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 71-311 4.66e-69

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 215.93  E-value: 4.66e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  71 RGLIAVIHGYTDESSWLIQLTAiAIAKAGFYVCALDLQGHGNSDGVRGHIPDIEPVVEDCVQFFDSARASHPKLPAFIFG 150
Cdd:pfam12146   4 RAVVVLVHGLGEHSGRYAHLAD-ALAAQGFAVYAYDHRGHGRSDGKRGHVPSFDDYVDDLDTFVDKIREEHPGLPLFLLG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 151 ESLGGAIAILMCLKQRNSeWSGLILNGAMCGVSKKFkPVWPLEQLLPAAAFVAPTWKIAITEDPAKRSyKEEWKRRLVMK 230
Cdd:pfam12146  83 HSMGGLIAALYALRYPDK-VDGLILSAPALKIKPYL-APPILKLLAKLLGKLFPRLRVPNNLLPDSLS-RDPEVVAAYAA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 231 SPNRAanGKVTAATALEFLRVCEYIKRNSHGLKIPLLVVHGGDDKICDPKSARLLYESAASEDKTLKIFTGMWHQFIGEP 310
Cdd:pfam12146 160 DPLVH--GGISARTLYELLDAGERLLRRAAAITVPLLLLHGGADRVVDPAGSREFYERAGSTDKTLKLYPGLYHELLNEP 237


                  .
gi 1585793756 311 N 311
Cdd:pfam12146 238 D 238
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
54-327 5.17e-39

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 137.83  E-value: 5.17e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  54 NIKIFTQSWLPSSAPRlrGLIAVIHGYTdESSWLIQLTAIAIAKAGFYVCALDLQGHGNSDGVRGHIPDIEPVVEDCVQF 133
Cdd:COG2267    13 GLRLRGRRWRPAGSPR--GTVVLVHGLG-EHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPRGHVDSFDDYVDDLRAA 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 134 FDSARAsHPKLPAFIFGESLGGAIAILMcLKQRNSEWSGLILngamcgvskkfkpvwpleqllpaaafVAPtwkiAITED 213
Cdd:COG2267    90 LDALRA-RPGLPVVLLGHSMGGLIALLY-AARYPDRVAGLVL--------------------------LAP----AYRAD 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 214 PAkrsykeewkrrlvmkspnraanGKVTAATALEfLRVCEYIKRnshgLKIPLLVVHGGDDKICDPKSARLLYEsAASED 293
Cdd:COG2267   138 PL----------------------LGPSARWLRA-LRLAEALAR----IDVPVLVLHGGADRVVPPEAARRLAA-RLSPD 189

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1585793756 294 KTLKIFTGMWHQFIGEPNEsvEQVFGTILTWIGE 327
Cdd:COG2267   190 VELVLLPGARHELLNEPAR--EEVLAAILAWLER 221
PST-A TIGR01607
Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in ...
 51-325 6.37e-15

Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in Plasmodium falciparum and Plasmodium yoelii, which are closely related to various phospholipases and lysophospholipases of plants as well as generally being related to the alpha/beta-fold superfamily of hydrolases. These genes are preferentially located in the subtelomeric regions of the chromosomes of both P. falciparum and P. yoelii.


Pssm-ID: 162444 [Multi-domain]  Cd Length: 332  Bit Score: 74.43  E-value: 6.37e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  51 NKQNIKIFTQSWLPSSAprlRGLIAVIHG------------------------------YTDESSWLIQLTaiaiaKAGF 100
Cdd:TIGR01607   4 NKDGLLLKTYSWIVKNA---IGIIVLIHGlkshlrlqflkinakivnndravlidtdnyYIYKDSWIENFN-----KNGY 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 101 YVCALDLQGHGNSDG---VRGHIPDIEPVVEDCVQFFDSARAS--------------------HPKLPAFIFGESLGGAI 157
Cdd:TIGR01607  76 SVYGLDLQGHGESDGlqnLRGHINCFDDLVYDVIQYMNRINDSiilenetksddesydivntkENRLPMYIIGLSMGGNI 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 158 AI--LMCLKQRNSEWSGLILNG--AMCGV----------SKKFKPVW-PLEQLLpaaAFVAPTWKIAitedPAKRSYKEE 222
Cdd:TIGR01607 156 ALrlLELLGKSNENNDKLNIKGciSLSGMisiksvgsddSFKFKYFYlPVMNFM---SRVFPTFRIS----KKIRYEKSP 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 223 WKRRLVMKSPNRaANGKVTAATALEFLRVCEYIKRNSHGL--KIPLLVVHGGDDKICDPKSARLLYESAASEDKTLKIFT 300
Cdd:TIGR01607 229 YVNDIIKFDKFR-YDGGITFNLASELIKATDTLDCDIDYIpkDIPILFIHSKGDCVCSYEGTVSFYNKLSISNKELHTLE 307

                         330       340
                  ....*....|....*....|....*
gi 1585793756 301 GMWHQFIGEPNEsvEQVFGTILTWI 325
Cdd:TIGR01607 308 DMDHVITIEPGN--EEVLKKIIEWI 330
 
Name Accession Description Interval E-value
PLN02298 PLN02298
hydrolase, alpha/beta fold family protein
 27-340 1.39e-100

hydrolase, alpha/beta fold family protein


Pssm-ID: 165939 [Multi-domain]  Cd Length: 330  Bit Score: 299.77  E-value: 1.39e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  27 PFGDLTREDFYNKHQILHQESFMLNKQNIKIFTQSWLPSSAPRLRGLIAVIHGYTDESSWLIQLTAIAIAKAGFYVCALD 106
Cdd:PLN02298   15 FWGETPEEEYYALKGIKGSKSFFTSPRGLSLFTRSWLPSSSSPPRALIFMVHGYGNDISWTFQSTAIFLAQMGFACFALD 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 107 LQGHGNSDGVRGHIPDIEPVVEDCVQFFDS--ARASHPKLPAFIFGESLGGAIAILMCLKQRNsEWSGLILNGAMCGVSK 184
Cdd:PLN02298   95 LEGHGRSEGLRAYVPNVDLVVEDCLSFFNSvkQREEFQGLPRFLYGESMGGAICLLIHLANPE-GFDGAVLVAPMCKISD 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 185 KFKPVWPLEQLLPAAAFVAPTWKIAITEDPAKRSYKEEWKRRLVMKSPNRaANGKVTAATALEFLRVCEYIKRNSHGLKI 264
Cdd:PLN02298  174 KIRPPWPIPQILTFVARFLPTLAIVPTADLLEKSVKVPAKKIIAKRNPMR-YNGKPRLGTVVELLRVTDYLGKKLKDVSI 252

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1585793756 265 PLLVVHGGDDKICDPKSARLLYESAASEDKTLKIFTGMWHQFI-GEPNESVEQVFGTILTWIGERADNASETYSNNG 340
Cdd:PLN02298  253 PFIVLHGSADVVTDPDVSRALYEEAKSEDKTIKIYDGMMHSLLfGEPDENIEIVRRDILSWLNERCTGKATPSEDSI 329
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 71-311 4.66e-69

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 215.93  E-value: 4.66e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  71 RGLIAVIHGYTDESSWLIQLTAiAIAKAGFYVCALDLQGHGNSDGVRGHIPDIEPVVEDCVQFFDSARASHPKLPAFIFG 150
Cdd:pfam12146   4 RAVVVLVHGLGEHSGRYAHLAD-ALAAQGFAVYAYDHRGHGRSDGKRGHVPSFDDYVDDLDTFVDKIREEHPGLPLFLLG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 151 ESLGGAIAILMCLKQRNSeWSGLILNGAMCGVSKKFkPVWPLEQLLPAAAFVAPTWKIAITEDPAKRSyKEEWKRRLVMK 230
Cdd:pfam12146  83 HSMGGLIAALYALRYPDK-VDGLILSAPALKIKPYL-APPILKLLAKLLGKLFPRLRVPNNLLPDSLS-RDPEVVAAYAA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 231 SPNRAanGKVTAATALEFLRVCEYIKRNSHGLKIPLLVVHGGDDKICDPKSARLLYESAASEDKTLKIFTGMWHQFIGEP 310
Cdd:pfam12146 160 DPLVH--GGISARTLYELLDAGERLLRRAAAITVPLLLLHGGADRVVDPAGSREFYERAGSTDKTLKLYPGLYHELLNEP 237


                  .
gi 1585793756 311 N 311
Cdd:pfam12146 238 D 238
PLN02385 PLN02385
hydrolase; alpha/beta fold family protein
 45-332 8.69e-64

hydrolase; alpha/beta fold family protein


Pssm-ID: 215216 [Multi-domain]  Cd Length: 349  Bit Score: 206.14  E-value: 8.69e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  45 QESFMLNKQNIKIFTQSWLPSSApRLRGLIAVIHGYTDESSWLIQLTAIAIAKAGFYVCALDLQGHGNSDGVRGHIPDIE 124
Cdd:PLN02385   62 EESYEVNSRGVEIFSKSWLPENS-RPKAAVCFCHGYGDTCTFFFEGIARKIASSGYGVFAMDYPGFGLSEGLHGYIPSFD 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 125 PVVEDCVQFFDS--ARASHPKLPAFIFGESLGGAIAILMCLKQRNsEWSGLILNGAMCGVSKKFKPVWPLEQLLPAAAFV 202
Cdd:PLN02385  141 DLVDDVIEHYSKikGNPEFRGLPSFLFGQSMGGAVALKVHLKQPN-AWDGAILVAPMCKIADDVVPPPLVLQILILLANL 219

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 203 APTWKIAITEDPAKRSYKEEWKRRlvMKSPNRAA-NGKVTAATALEFLRVCEYIKRNSHGLKIPLLVVHGGDDKICDPKS 281
Cdd:PLN02385  220 LPKAKLVPQKDLAELAFRDLKKRK--MAEYNVIAyKDKPRLRTAVELLRTTQEIEMQLEEVSLPLLILHGEADKVTDPSV 297

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1585793756 282 ARLLYESAASEDKTLKIFTGMWHQFI-GEPNESVEQVFGTILTWIGERADNA 332
Cdd:PLN02385  298 SKFLYEKASSSDKKLKLYEDAYHSILeGEPDEMIFQVLDDIISWLDSHSTQK 349
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
54-327 5.17e-39

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 137.83  E-value: 5.17e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  54 NIKIFTQSWLPSSAPRlrGLIAVIHGYTdESSWLIQLTAIAIAKAGFYVCALDLQGHGNSDGVRGHIPDIEPVVEDCVQF 133
Cdd:COG2267    13 GLRLRGRRWRPAGSPR--GTVVLVHGLG-EHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPRGHVDSFDDYVDDLRAA 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 134 FDSARAsHPKLPAFIFGESLGGAIAILMcLKQRNSEWSGLILngamcgvskkfkpvwpleqllpaaafVAPtwkiAITED 213
Cdd:COG2267    90 LDALRA-RPGLPVVLLGHSMGGLIALLY-AARYPDRVAGLVL--------------------------LAP----AYRAD 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 214 PAkrsykeewkrrlvmkspnraanGKVTAATALEfLRVCEYIKRnshgLKIPLLVVHGGDDKICDPKSARLLYEsAASED 293
Cdd:COG2267   138 PL----------------------LGPSARWLRA-LRLAEALAR----IDVPVLVLHGGADRVVPPEAARRLAA-RLSPD 189

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1585793756 294 KTLKIFTGMWHQFIGEPNEsvEQVFGTILTWIGE 327
Cdd:COG2267   190 VELVLLPGARHELLNEPAR--EEVLAAILAWLER 221
PLN02652 PLN02652
hydrolase; alpha/beta fold family protein
 57-330 1.41e-37

hydrolase; alpha/beta fold family protein


Pssm-ID: 215352 [Multi-domain]  Cd Length: 395  Bit Score: 138.87  E-value: 1.41e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  57 IFTQSWLPSSApRLRGLIAVIHGYTDESSWLIQLtAIAIAKAGFYVCALDLQGHGNSDGVRGHIPDIEPVVEDCVQFFDS 136
Cdd:PLN02652  123 LFCRSWAPAAG-EMRGILIIIHGLNEHSGRYLHF-AKQLTSCGFGVYAMDWIGHGGSDGLHGYVPSLDYVVEDTEAFLEK 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 137 ARASHPKLPAFIFGESLGGAIAILMCLKQR-NSEWSGLILNGAMCGVskkfKPVWPL-EQLLPAAAFVAPTWK------- 207
Cdd:PLN02652  201 IRSENPGVPCFLFGHSTGGAVVLKAASYPSiEDKLEGIVLTSPALRV----KPAHPIvGAVAPIFSLVAPRFQfkgankr 276

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 208 -IAITEDPAKRSYKeeWKRRLVMKSPNRAANGKvtaatalEFLRVCEYIKRNSHGLKIPLLVVHGGDDKICDPKSARLLY 286
Cdd:PLN02652  277 gIPVSRDPAALLAK--YSDPLVYTGPIRVRTGH-------EILRISSYLTRNFKSVTVPFMVLHGTADRVTDPLASQDLY 347

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1585793756 287 ESAASEDKTLKIFTGMWHQFIGEPNEsvEQVFGTILTWIGERAD 330
Cdd:PLN02652  348 NEAASRHKDIKLYDGFLHDLLFEPER--EEVGRDIIDWMEKRLD 389
PHA02857 PHA02857
monoglyceride lipase; Provisional
 48-329 6.90e-25

monoglyceride lipase; Provisional


Pssm-ID: 165193 [Multi-domain]  Cd Length: 276  Bit Score: 101.89  E-value: 6.90e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  48 FMLNKQNIKIFTQSWLPSSAPRlrGLIAVIHGyTDESSWLIQLTAIAIAKAGFYVCALDLQGHGNSDGVRGHIPDIEPVV 127
Cdd:PHA02857    4 CMFNLDNDYIYCKYWKPITYPK--ALVFISHG-AGEHSGRYEELAENISSLGILVFSHDHIGHGRSNGEKMMIDDFGVYV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 128 EDCVQFFDSARASHPKLPAFIFGESLGGAIAILMCLKQRNSeWSGLILNGAMCGVSKKFKPVWPLEQLLPAAAFVAPTWK 207
Cdd:PHA02857   81 RDVVQHVVTIKSTYPGVPVFLLGHSMGATISILAAYKNPNL-FTAMILMSPLVNAEAVPRLNLLAAKLMGIFYPNKIVGK 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 208 IAIteDPAKRSYKEEWKRRLvmkSPNRAANgKVTAATALEFLRVCEYIKRNSHGLKIPLLVVHGGDDKICDPKSARLLYE 287
Cdd:PHA02857  160 LCP--ESVSRDMDEVYKYQY---DPLVNHE-KIKAGFASQVLKATNKVRKIIPKIKTPILILQGTNNEISDVSGAYYFMQ 233

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1585793756 288 SAASeDKTLKIFTGMWHQFIGEPNESVEQVFGTILTWIGERA 329
Cdd:PHA02857  234 HANC-NREIKIYEGAKHHLHKETDEVKKSVMKEIETWIFNRV 274
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
77-329 7.51e-25

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 100.79  E-value: 7.51e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  77 IHGYTDeSSWLIQLTAIAIAKAGFYVCALDLQGHGNSDGvrghipDIEPV-VEDCVQF----FDSARASHPKLpaFIFGE 151
Cdd:COG1647    21 LHGFTG-SPAEMRPLAEALAKAGYTVYAPRLPGHGTSPE------DLLKTtWEDWLEDveeaYEILKAGYDKV--IVIGL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 152 SLGGAIAILMClkQRNSEWSGLIL-NGAMcgvskKFKPvwPLEQLLPAAAFVAPTWKiAITEDPAKRSYKEEWKRRLVMK 230
Cdd:COG1647    92 SMGGLLALLLA--ARYPDVAGLVLlSPAL-----KIDD--PSAPLLPLLKYLARSLR-GIGSDIEDPEVAEYAYDRTPLR 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 231 SpnraangkvtaatALEFLRVCEYIKRNSHGLKIPLLVVHGGDDKICDPKSARLLYESAASEDKTLKIFTGMWHQFIGEP 310
Cdd:COG1647   162 A-------------LAELQRLIREVRRDLPKITAPTLIIQSRKDEVVPPESARYIYERLGSPDKELVWLEDSGHVITLDK 228

                         250
                  ....*....|....*....
gi 1585793756 311 NesVEQVFGTILTWIGERA 329
Cdd:COG1647   229 D--REEVAEEILDFLERLA 245
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
63-327 8.55e-16

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 75.44  E-value: 8.55e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  63 LPSSAPRlRGLIAVIHGYTDESSWLIQLTAIAIAKAGFYVCALDLQGHGNSDGVRGHIPdiepvVEDCVQFFDSARAsHP 142
Cdd:COG1506    16 LPADGKK-YPVVVYVHGGPGSRDDSFLPLAQALASRGYAVLAPDYRGYGESAGDWGGDE-----VDDVLAAIDYLAA-RP 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 143 KLPA---FIFGESLGGAIAiLMCLKQRNSEWSGLIlngAMCGVSkkfkpvwPLEQLLPAAAFVAPTWKIAITEDPakrsy 219
Cdd:COG1506    89 YVDPdriGIYGHSYGGYMA-LLAAARHPDRFKAAV---ALAGVS-------DLRSYYGTTREYTERLMGGPWEDP----- 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 220 kEEWKRRlvmkSPNRAAngkvtaataleflrvceyikrnsHGLKIPLLVVHGGDDKICDPKSARLLYESA--ASEDKTLK 297
Cdd:COG1506   153 -EAYAAR----SPLAYA-----------------------DKLKTPLLLIHGEADDRVPPEQAERLYEALkkAGKPVELL 204

                         250       260       270
                  ....*....|....*....|....*....|
gi 1585793756 298 IFTGMWHQFIGEPNesvEQVFGTILTWIGE 327
Cdd:COG1506   205 VYPGEGHGFSGAGA---PDYLERILDFLDR 231
PST-A TIGR01607
Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in ...
 51-325 6.37e-15

Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in Plasmodium falciparum and Plasmodium yoelii, which are closely related to various phospholipases and lysophospholipases of plants as well as generally being related to the alpha/beta-fold superfamily of hydrolases. These genes are preferentially located in the subtelomeric regions of the chromosomes of both P. falciparum and P. yoelii.


Pssm-ID: 162444 [Multi-domain]  Cd Length: 332  Bit Score: 74.43  E-value: 6.37e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  51 NKQNIKIFTQSWLPSSAprlRGLIAVIHG------------------------------YTDESSWLIQLTaiaiaKAGF 100
Cdd:TIGR01607   4 NKDGLLLKTYSWIVKNA---IGIIVLIHGlkshlrlqflkinakivnndravlidtdnyYIYKDSWIENFN-----KNGY 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 101 YVCALDLQGHGNSDG---VRGHIPDIEPVVEDCVQFFDSARAS--------------------HPKLPAFIFGESLGGAI 157
Cdd:TIGR01607  76 SVYGLDLQGHGESDGlqnLRGHINCFDDLVYDVIQYMNRINDSiilenetksddesydivntkENRLPMYIIGLSMGGNI 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 158 AI--LMCLKQRNSEWSGLILNG--AMCGV----------SKKFKPVW-PLEQLLpaaAFVAPTWKIAitedPAKRSYKEE 222
Cdd:TIGR01607 156 ALrlLELLGKSNENNDKLNIKGciSLSGMisiksvgsddSFKFKYFYlPVMNFM---SRVFPTFRIS----KKIRYEKSP 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 223 WKRRLVMKSPNRaANGKVTAATALEFLRVCEYIKRNSHGL--KIPLLVVHGGDDKICDPKSARLLYESAASEDKTLKIFT 300
Cdd:TIGR01607 229 YVNDIIKFDKFR-YDGGITFNLASELIKATDTLDCDIDYIpkDIPILFIHSKGDCVCSYEGTVSFYNKLSISNKELHTLE 307

                         330       340
                  ....*....|....*....|....*
gi 1585793756 301 GMWHQFIGEPNEsvEQVFGTILTWI 325
Cdd:TIGR01607 308 DMDHVITIEPGN--EEVLKKIIEWI 330
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 36-327 1.43e-13

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 69.56  E-value: 1.43e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  36 FYNKHQILHQESFMLNKQNIKIFTQSWLPSSAPRLRGLIAVIHGYTD--ESSWLIqltAIAIAKAGFYVCALDLQGHGNS 113
Cdd:COG1073     2 FPPSDKVNKEDVTFKSRDGIKLAGDLYLPAGASKKYPAVVVAHGNGGvkEQRALY---AQRLAELGFNVLAFDYRGYGES 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 114 DGvrghipdiEPVVEDCVQFFDSARA-----SHPKLPA---FIFGESLGGAIAILMCLKQRNSewSGLILngaMCGVSkk 185
Cdd:COG1073    79 EG--------EPREEGSPERRDARAAvdylrTLPGVDPeriGLLGISLGGGYALNAAATDPRV--KAVIL---DSPFT-- 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 186 fkpvwpleQLLPAAAFVAptwkiaitedpakrsyKEEWKRRLVMKS--PNraangkvtaATALEFLR----VCEYIKRns 259
Cdd:COG1073   144 --------SLEDLAAQRA----------------KEARGAYLPGVPylPN---------VRLASLLNdefdPLAKIEK-- 188

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1585793756 260 hgLKIPLLVVHGGDDKICDPKSARLLYEsAASEDKTLKIFTGMWH-QFIGEPNesvEQVFGTILTWIGE 327
Cdd:COG1073   189 --ISRPLLFIHGEKDEAVPFYMSEDLYE-AAAEPKELLIVPGAGHvDLYDRPE---EEYFDKLAEFFKK 251
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 77-328 7.86e-11

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 61.17  E-value: 7.86e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  77 IHGY-TDESSWLIQLTAIAiakAGFYVCALDLQGHGNSDGVRGHIpDIEPVVEDCVQFFDSARAShpklPAFIFGESLGG 155
Cdd:COG0596    29 LHGLpGSSYEWRPLIPALA---AGYRVIAPDLRGHGRSDKPAGGY-TLDDLADDLAALLDALGLE----RVVLVGHSMGG 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 156 AIAILMCLkQRNSEWSGLILNGAMcgvskkfkpvwpleqllpAAAFVAPtwkiaitedpakrsykeewkrrlvMKSPNRA 235
Cdd:COG0596   101 MVALELAA-RHPERVAGLVLVDEV------------------LAALAEP------------------------LRRPGLA 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 236 ANGKVTAATALEFLRVCEYIKRnshgLKIPLLVVHGGDDKICDPKSARLLYEsaASEDKTLKIFTGMWHQFigePNESVE 315
Cdd:COG0596   138 PEALAALLRALARTDLRERLAR----ITVPTLVIWGEKDPIVPPALARRLAE--LLPNAELVVLPGAGHFP---PLEQPE 208

                         250
                  ....*....|...
gi 1585793756 316 QVFGTILTWIGER 328
Cdd:COG0596   209 AFAAALRDFLARL 221
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 76-285 1.36e-08

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 54.82  E-value: 1.36e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  76 VIHGYTDES-SWLIQltAIAIAKAGFYVCALDLQGHGNSDgvrGHIPDIEPVVEDCVQFFDSARASHPKLPAFIFGESLG 154
Cdd:pfam00561   5 LLHGLPGSSdLWRKL--APALARDGFRVIALDLRGFGKSS---RPKAQDDYRTDDLAEDLEYILEALGLEKVNLVGHSMG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 155 GAIAILMCLKqRNSEWSGLILngaMCGVSKKFKpvWPLEQLLPAAAFV--APTWKIAITEDPAKRSY------------- 219
Cdd:pfam00561  80 GLIALAYAAK-YPDRVKALVL---LGALDPPHE--LDEADRFILALFPgfFDGFVADFAPNPLGRLVakllallllrlrl 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1585793756 220 ---KEEWKRRLVMKSPNRAANGKVTAATALEFLRVCEYIKRnSHGLKIPLLVVHGGDDKICDPKSARLL 285
Cdd:pfam00561 154 lkaLPLLNKRFPSGDYALAKSLVTGALLFIETWSTELRAKF-LGRLDEPTLIIWGDQDPLVPPQALEKL 221
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 76-315 1.44e-08

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 54.40  E-value: 1.44e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  76 VIHGYTDESSWLIQLTAiaiakAGFYVCALDLQGHGNSDGVRGHIPDiepvVEDCVQFFDSARASHpklPAFIFGESLGG 155
Cdd:pfam12697   3 LVHGAGLSAAPLAALLA-----AGVAVLAPDLPGHGSSSPPPLDLAD----LADLAALLDELGAAR---PVVLVGHSLGG 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 156 AIAILMCLKQRnseWSGLILNGAMCGVSKKFKPVWPLEQLLPAAAfvAPTWKIAITEDP---AKRSYKEEWKRRLvmkSP 232
Cdd:pfam12697  71 AVALAAAAAAL---VVGVLVAPLAAPPGLLAALLALLARLGAALA--APAWLAAESLARgflDDLPADAEWAAAL---AR 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756 233 NRAANGKVTAATALEFLRVceyikrnshglkIPLLVVHGGDDKICDPKSARLLyesAASEDKTLKIFTGMWHQFIGEPNE 312
Cdd:pfam12697 143 LAALLAALALLPLAAWRDL------------PVPVLVLAEEDRLVPELAQRLL---AALAGARLVVLPGAGHLPLDDPEE 207


                  ...
gi 1585793756 313 SVE 315
Cdd:pfam12697 208 VAE 210
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
 77-158 1.18e-04

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 43.39  E-value: 1.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  77 IHGYT-DESSWLIQLTAIAIAKAgfyVCALDLQGHGNS--DGVRGHIPDIEPVVEDCVQFFDSARAsHpklpafIFGESL 153
Cdd:PRK14875  137 IHGFGgDLNNWLFNHAALAAGRP---VIALDLPGHGASskAVGAGSLDELAAAVLAFLDALGIERA-H------LVGHSM 206


                  ....*
gi 1585793756 154 GGAIA 158
Cdd:PRK14875  207 GGAVA 211
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
62-161 2.77e-03

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 38.79  E-value: 2.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  62 WLPSSAPRlRGLIAVIHGYTDESSWlIQLTAIAIAKAGFYVCALDLQGHG----NSDGVRGHIP--DIEPVVEDCVQFFD 135
Cdd:COG0412    21 ARPAGGGP-RPGVVVLHEIFGLNPH-IRDVARRLAAAGYVVLAPDLYGRGgpgdDPDEARALMGalDPELLAADLRAALD 98

                          90       100
                  ....*....|....*....|....*....
gi 1585793756 136 SARAsHPKLPA---FIFGESLGGAIAILM 161
Cdd:COG0412    99 WLKA-QPEVDAgrvGVVGFCFGGGLALLA 126
PRK10749 PRK10749
lysophospholipase L2; Provisional
 99-196 2.96e-03

lysophospholipase L2; Provisional


Pssm-ID: 182697  Cd Length: 330  Bit Score: 39.21  E-value: 2.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1585793756  99 GFYVCALDLQGHGNS-----DGVRGHIPDIEPVVEDCVQFFDSARASHPKLPAFIFGESLGGAIAILMCLKQRnSEWSGL 173
Cdd:PRK10749   81 GYDVLIIDHRGQGRSgrlldDPHRGHVERFNDYVDDLAAFWQQEIQPGPYRKRYALAHSMGGAILTLFLQRHP-GVFDAI 159

                          90       100
                  ....*....|....*....|...
gi 1585793756 174 ILNGAMCGVSKKFkPVWPLEQLL 196
Cdd:PRK10749  160 ALCAPMFGIVLPL-PSWMARRIL 181
PRK11126 PRK11126
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Provisional
 104-178 3.20e-03

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Provisional


Pssm-ID: 236855 [Multi-domain]  Cd Length: 242  Bit Score: 38.67  E-value: 3.20e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1585793756 104 ALDLQGHGNSdgvrghiPDIEPV-VEDCVQFFDSARASHPKLPAFIFGESLGGAIAILMCLKQRNSEWSGLILNGA 178
Cdd:PRK11126   32 YIDLPGHGGS-------AAISVDgFADVSRLLSQTLQSYNILPYWLVGYSLGGRIAMYYACQGLAGGLCGLIVEGG 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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