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Conserved domains on  [gi|1491393031|ref|XP_026646551|]
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lambda-crystallin homolog isoform X2 [Zonotrichia albicollis]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK06129 super family cl35428
3-hydroxyacyl-CoA dehydrogenase; Validated
 1-261 4.03e-96

3-hydroxyacyl-CoA dehydrogenase; Validated


The actual alignment was detected with superfamily member PRK06129:

Pssm-ID: 235706 [Multi-domain]  Cd Length: 308  Bit Score: 284.63  E-value: 4.03e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031   1 MQEMEKSGVLKGAlSAEQQLALISVCTDLKAAVEGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKLF 80
Cdd:PRK06129   49 LEDLAAFDLLDGE-APDAVLARIRVTDSLADAVADADYVQESAPENLELKRALFAELDALAPPHAILASSTSALLASAFT 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  81 TGLKHVKQCIVSHPVNPPYFVPLVEIVPHPETDPSTTERTYALMKKIGQSPVKLNREIEGFVLNRLQYAVISEAWRLVGE 160
Cdd:PRK06129  128 EHLAGRERCLVAHPINPPYLIPVVEVVPAPWTAPATLARAEALYRAAGQSPVRLRREIDGFVLNRLQGALLREAFRLVAD 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031 161 GVISPTDLDLVMSDGLGMRYAFIGPLETMHLNA-EGVSSYCERYAEGMKLVLNTFG-PVPeFSGETVQKVNQALSEKIPV 238
Cdd:PRK06129  208 GVASVDDIDAVIRDGLGLRWSFMGPFETIDLNApGGVADYAQRYGPMYRRMAAERGqPVP-WDGELVARVEAERRAALPL 286

                         250       260
                  ....*....|....*....|...
gi 1491393031 239 apKALDARRKWRDECLTGLAKLK 261
Cdd:PRK06129  287 --DQLAARQAWRDRRLMALAAHR 307
 
Name Accession Description Interval E-value
PRK06129 PRK06129
3-hydroxyacyl-CoA dehydrogenase; Validated
 1-261 4.03e-96

3-hydroxyacyl-CoA dehydrogenase; Validated


Pssm-ID: 235706 [Multi-domain]  Cd Length: 308  Bit Score: 284.63  E-value: 4.03e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031   1 MQEMEKSGVLKGAlSAEQQLALISVCTDLKAAVEGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKLF 80
Cdd:PRK06129   49 LEDLAAFDLLDGE-APDAVLARIRVTDSLADAVADADYVQESAPENLELKRALFAELDALAPPHAILASSTSALLASAFT 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  81 TGLKHVKQCIVSHPVNPPYFVPLVEIVPHPETDPSTTERTYALMKKIGQSPVKLNREIEGFVLNRLQYAVISEAWRLVGE 160
Cdd:PRK06129  128 EHLAGRERCLVAHPINPPYLIPVVEVVPAPWTAPATLARAEALYRAAGQSPVRLRREIDGFVLNRLQGALLREAFRLVAD 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031 161 GVISPTDLDLVMSDGLGMRYAFIGPLETMHLNA-EGVSSYCERYAEGMKLVLNTFG-PVPeFSGETVQKVNQALSEKIPV 238
Cdd:PRK06129  208 GVASVDDIDAVIRDGLGLRWSFMGPFETIDLNApGGVADYAQRYGPMYRRMAAERGqPVP-WDGELVARVEAERRAALPL 286

                         250       260
                  ....*....|....*....|...
gi 1491393031 239 apKALDARRKWRDECLTGLAKLK 261
Cdd:PRK06129  287 --DQLAARQAWRDRRLMALAAHR 307
FadB COG1250
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA ...
 1-191 1.82e-61

3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA dehydrogenase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440862 [Multi-domain]  Cd Length: 281  Bit Score: 194.94  E-value: 1.82e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031   1 MQEMEKS---GVLKGALSAEQ---QLALISVCTDLkAAVEGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCL 74
Cdd:COG1250    42 RARIAKLldkLVKKGKLTEEEadaALARITPTTDL-AALADADLVIEAVPEDLDLKQEVFAELDAVAPPDAILASNTSSL 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  75 LPSKLFTGLKHVKQCIVSHPVNPPYFVPLVEIVPHPETDPSTTERTYALMKKIGQSPVKLNrEIEGFVLNRLQYAVISEA 154
Cdd:COG1250   121 SITELAAATKRPERFIGLHFFNPVPLMPLVEVIRGPATSDETVATAVAFARRLGKTPVVVK-DTPGFIVNRILVPYLNEA 199

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1491393031 155 WRLVGEGVISPTDLDLVMSDGLGMRyafIGPLETMHL 191
Cdd:COG1250   200 IRLLEEGVASPEDIDAAMRLGFGFP---MGPFELADL 233
3HCDH_N pfam02737
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda ...
 9-135 1.28e-43

3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda crystallin.


Pssm-ID: 397037 [Multi-domain]  Cd Length: 180  Bit Score: 146.14  E-value: 1.28e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031   9 VLKGALSAEQ---QLALISVCTDLKAAVeGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKLFTGLKH 85
Cdd:pfam02737  50 VEKGRITEEEvdaALARISFTTDLAAAV-DADLVIEAVPENLELKRKLFAELDAIAPPDAILATNTSSLSITELAAATKR 128

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1491393031  86 VKQCIVSHPVNPPYFVPLVEIVPHPETDPSTTERTYALMKKIGQSPVKLN 135
Cdd:pfam02737 129 PERFIGLHFFNPPPLMPLVEVVRGEKTSPETVATTVELAKKIGKTPVVVK 178
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 32-169 7.71e-10

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 59.08  E-value: 7.71e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  32 AVEGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKLFTGLKHVKQCIVSHPVNPPYFVPLVEIVPHPE 111
Cdd:TIGR02441 411 GFKNADMVIEAVFEDLSLKHKVIKEVEAVVPPHCIIASNTSALPIKDIAAVSSRPEKVIGMHYFSPVDKMQLLEIITHDG 490

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1491393031 112 TDPSTTERTYALMKKIGQSPVKLnREIEGFVLNRLQYAVISEAWRLVGEGViSPTDLD 169
Cdd:TIGR02441 491 TSKDTLASAVAVGLKQGKVVIVV-KDGPGFYTTRCLGPMLAEVIRLLQEGV-DPKKLD 546
 
Name Accession Description Interval E-value
PRK06129 PRK06129
3-hydroxyacyl-CoA dehydrogenase; Validated
 1-261 4.03e-96

3-hydroxyacyl-CoA dehydrogenase; Validated


Pssm-ID: 235706 [Multi-domain]  Cd Length: 308  Bit Score: 284.63  E-value: 4.03e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031   1 MQEMEKSGVLKGAlSAEQQLALISVCTDLKAAVEGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKLF 80
Cdd:PRK06129   49 LEDLAAFDLLDGE-APDAVLARIRVTDSLADAVADADYVQESAPENLELKRALFAELDALAPPHAILASSTSALLASAFT 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  81 TGLKHVKQCIVSHPVNPPYFVPLVEIVPHPETDPSTTERTYALMKKIGQSPVKLNREIEGFVLNRLQYAVISEAWRLVGE 160
Cdd:PRK06129  128 EHLAGRERCLVAHPINPPYLIPVVEVVPAPWTAPATLARAEALYRAAGQSPVRLRREIDGFVLNRLQGALLREAFRLVAD 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031 161 GVISPTDLDLVMSDGLGMRYAFIGPLETMHLNA-EGVSSYCERYAEGMKLVLNTFG-PVPeFSGETVQKVNQALSEKIPV 238
Cdd:PRK06129  208 GVASVDDIDAVIRDGLGLRWSFMGPFETIDLNApGGVADYAQRYGPMYRRMAAERGqPVP-WDGELVARVEAERRAALPL 286

                         250       260
                  ....*....|....*....|...
gi 1491393031 239 apKALDARRKWRDECLTGLAKLK 261
Cdd:PRK06129  287 --DQLAARQAWRDRRLMALAAHR 307
FadB COG1250
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA ...
 1-191 1.82e-61

3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA dehydrogenase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440862 [Multi-domain]  Cd Length: 281  Bit Score: 194.94  E-value: 1.82e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031   1 MQEMEKS---GVLKGALSAEQ---QLALISVCTDLkAAVEGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCL 74
Cdd:COG1250    42 RARIAKLldkLVKKGKLTEEEadaALARITPTTDL-AALADADLVIEAVPEDLDLKQEVFAELDAVAPPDAILASNTSSL 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  75 LPSKLFTGLKHVKQCIVSHPVNPPYFVPLVEIVPHPETDPSTTERTYALMKKIGQSPVKLNrEIEGFVLNRLQYAVISEA 154
Cdd:COG1250   121 SITELAAATKRPERFIGLHFFNPVPLMPLVEVIRGPATSDETVATAVAFARRLGKTPVVVK-DTPGFIVNRILVPYLNEA 199

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1491393031 155 WRLVGEGVISPTDLDLVMSDGLGMRyafIGPLETMHL 191
Cdd:COG1250   200 IRLLEEGVASPEDIDAAMRLGFGFP---MGPFELADL 233
PRK06130 PRK06130
3-hydroxybutyryl-CoA dehydrogenase; Validated
 8-199 6.41e-49

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 235707 [Multi-domain]  Cd Length: 311  Bit Score: 163.79  E-value: 6.41e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031   8 GVLKGALSAEQQLALISVCTDLKAAVEGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKLFTGLKHVK 87
Cdd:PRK06130   52 GVYAPLGIASAGMGRIRMEAGLAAAVSGADLVIEAVPEKLELKRDVFARLDGLCDPDTIFATNTSGLPITAIAQAVTRPE 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  88 QCIVSHPVNPPYFVPLVEIVPHPETDPSTTERTYALMKKIGQSPVKLNREIEGFVLNRLQYAVISEAWRLVGEGVISPTD 167
Cdd:PRK06130  132 RFVGTHFFTPADVIPLVEVVRGDKTSPQTVATTMALLRSIGKRPVLVKKDIPGFIANRIQHALAREAISLLEKGVASAED 211

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1491393031 168 LDLVMSDGLGMRYAFIGPLETMHLNA----EGVSSY 199
Cdd:PRK06130  212 IDEVVKWSLGIRLALTGPLEQRDMNGldvhLAVASY 247
PRK07531 PRK07531
carnitine 3-dehydrogenase;
23-228 1.01e-45

carnitine 3-dehydrogenase;


Pssm-ID: 236044 [Multi-domain]  Cd Length: 495  Bit Score: 159.90  E-value: 1.01e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  23 ISVCTDLKAAVEGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKLFTGLKHVKQCIVSHPVNPPYFVP 102
Cdd:PRK07531   68 LTFCASLAEAVAGADWIQESVPERLDLKRRVLAEIDAAARPDALIGSSTSGFLPSDLQEGMTHPERLFVAHPYNPVYLLP 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031 103 LVEIVPHPETDPSTTERTYALMKKIGQSPVKLNREIEGFVLNRLQYAVISEAWRLVGEGVISPTDLDLVMSDGLGMRYAF 182
Cdd:PRK07531  148 LVELVGGGKTSPETIRRAKEILREIGMKPVHIAKEIDAFVGDRLLEALWREALWLVKDGIATTEEIDDVIRYSFGLRWAQ 227

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1491393031 183 IGPLETMHLnAEGVSsyceryaeGMKLVLNTFGP-----------VPEFSGETVQKV 228
Cdd:PRK07531  228 MGLFETYRI-AGGEA--------GMRHFLAQFGPclkwpwtklmdVPDLDDALVDKI 275
3HCDH_N pfam02737
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda ...
 9-135 1.28e-43

3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda crystallin.


Pssm-ID: 397037 [Multi-domain]  Cd Length: 180  Bit Score: 146.14  E-value: 1.28e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031   9 VLKGALSAEQ---QLALISVCTDLKAAVeGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKLFTGLKH 85
Cdd:pfam02737  50 VEKGRITEEEvdaALARISFTTDLAAAV-DADLVIEAVPENLELKRKLFAELDAIAPPDAILATNTSSLSITELAAATKR 128

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1491393031  86 VKQCIVSHPVNPPYFVPLVEIVPHPETDPSTTERTYALMKKIGQSPVKLN 135
Cdd:pfam02737 129 PERFIGLHFFNPPPLMPLVEVVRGEKTSPETVATTVELAKKIGKTPVVVK 178
PRK07066 PRK07066
L-carnitine dehydrogenase;
4-255 2.02e-42

L-carnitine dehydrogenase;


Pssm-ID: 168796 [Multi-domain]  Cd Length: 321  Bit Score: 147.29  E-value: 2.02e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031   4 MEKSGVLKGAlsAEQQLALISVctdLKAAVEGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKLFTGL 83
Cdd:PRK07066   57 LERQGLAPGA--SPARLRFVAT---IEACVADADFIQESAPEREALKLELHERISRAAKPDAIIASSTSGLLPTDFYARA 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  84 KHVKQCIVSHPVNPPYFVPLVEIVPHPETDPSTTERTYALMKKIGQSPVKLNREIEGFVLNRLQYAVISEAWRLVGEGVI 163
Cdd:PRK07066  132 THPERCVVGHPFNPVYLLPLVEVLGGERTAPEAVDAAMGIYRALGMRPLHVRKEVPGFIADRLLEALWREALHLVNEGVA 211

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031 164 SPTDLDLVMSDGLGMRYAFIGPLETMHLNA--EGVSSYCERYAEGMKLVLnTFGPVPEFSGETVQKVNQALSEKipVAPK 241
Cdd:PRK07066  212 TTGEIDDAIRFGAGIRWSFMGTFLTYTLAGgdAGMRHFMQQFGPALELPW-TKLVAPELTDALIDRVVEGTAEQ--QGPR 288

                         250
                  ....*....|....
gi 1491393031 242 ALDARRKWRDECLT 255
Cdd:PRK07066  289 SIKALERYRDECIT 302
PRK08269 PRK08269
3-hydroxybutyryl-CoA dehydrogenase; Validated
 8-187 5.10e-35

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 181340 [Multi-domain]  Cd Length: 314  Bit Score: 127.48  E-value: 5.10e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031   8 GVLKGAlSAEQQLALISVCT--DLKAAVEGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKLFTGLKH 85
Cdd:PRK08269   51 GRIDAA-QADAVLARIAVVArdGAADALADADLVFEAVPEVLDAKREALRWLGRHVDADAIIASTTSTFLVTDLQRHVAH 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  86 VKQCIVSHPVNPPYFVPLVEIVPHPETDPSTTERTYALMKKIGQSPVKLnREIEGFVLNRLQYAVISEAWRLVGEGVISP 165
Cdd:PRK08269  130 PERFLNAHWLNPAYLMPLVEVSPSDATDPAVVDRLAALLERIGKVPVVC-GPSPGYIVPRIQALAMNEAARMVEEGVASA 208

                         170       180
                  ....*....|....*....|..
gi 1491393031 166 TDLDLVMSDGLGMRYAFIGPLE 187
Cdd:PRK08269  209 EDIDKAIRTGFGLRFAVLGLLE 230
PRK05808 PRK05808
3-hydroxybutyryl-CoA dehydrogenase; Validated
 9-186 6.71e-30

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 180269 [Multi-domain]  Cd Length: 282  Bit Score: 113.52  E-value: 6.71e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031   9 VLKGALSAEQQ---LALISVCTDLKAAVEgATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKLFTGLKH 85
Cdd:PRK05808   54 VKKGKMTEADKeaaLARITGTTDLDDLKD-ADLVIEAATENMDLKKKIFAQLDEIAKPEAILATNTSSLSITELAAATKR 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  86 VKQCIVSHPVNPPYFVPLVEIVPHPETDPSTTERTYALMKKIGQSPVKLNrEIEGFVLNRLQYAVISEAWRLVGEGVISP 165
Cdd:PRK05808  133 PDKVIGMHFFNPVPVMKLVEIIRGLATSDATHEAVEALAKKIGKTPVEVK-NAPGFVVNRILIPMINEAIFVLAEGVATA 211

                         170       180
                  ....*....|....*....|.
gi 1491393031 166 TDLDLVMSdgLGMRYAfIGPL 186
Cdd:PRK05808  212 EDIDEGMK--LGCNHP-IGPL 229
PLN02545 PLN02545
3-hydroxybutyryl-CoA dehydrogenase
 9-187 1.89e-29

3-hydroxybutyryl-CoA dehydrogenase


Pssm-ID: 215300 [Multi-domain]  Cd Length: 295  Bit Score: 112.52  E-value: 1.89e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031   9 VLKGALS---AEQQLALISVCTDLkAAVEGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKLFTGLKH 85
Cdd:PLN02545   55 VKKGKMSqeeADATLGRIRCTTNL-EELRDADFIIEAIVESEDLKKKLFSELDRICKPSAILASNTSSISITRLASATQR 133

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  86 VKQCIVSHPVNPPYFVPLVEIVPHPETDPSTTERTYALMKKIGQSPVKlNREIEGFVLNRLQYAVISEAWRLVGEGVISP 165
Cdd:PLN02545  134 PQQVIGMHFMNPPPIMKLVEIIRGADTSDEVFDATKALAERFGKTVVC-SQDYPGFIVNRILMPMINEAFYALYTGVASK 212

                         170       180
                  ....*....|....*....|..
gi 1491393031 166 TDLDLVMSDGLGMRyafIGPLE 187
Cdd:PLN02545  213 EDIDTGMKLGTNHP---MGPLH 231
PRK08268 PRK08268
3-hydroxy-acyl-CoA dehydrogenase; Validated
 9-197 1.05e-28

3-hydroxy-acyl-CoA dehydrogenase; Validated


Pssm-ID: 236211 [Multi-domain]  Cd Length: 507  Bit Score: 113.79  E-value: 1.05e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031   9 VLKGALSAEQ---QLALISVCTDLkAAVEGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKLFTGLKH 85
Cdd:PRK08268   58 VEKGKLTAEQadaALARLRPVEAL-ADLADCDLVVEAIVERLDVKQALFAQLEAIVSPDCILATNTSSLSITAIAAALKH 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  86 VKQCIVSHPVNPpyfVPL---VEIVPHPETDPSTTERTYALMKKIGQSPVKLnREIEGFVLNRLQYAVISEAWRLVGEGV 162
Cdd:PRK08268  137 PERVAGLHFFNP---VPLmklVEVVSGLATDPAVADALYALARAWGKTPVRA-KDTPGFIVNRAARPYYTEALRVLEEGV 212

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1491393031 163 ISPTDLDLVMSDGLGMRyafIGPLETMHLNAEGVS 197
Cdd:PRK08268  213 ADPATIDAILREAAGFR---MGPFELMDLIGLDVN 244
PRK09260 PRK09260
3-hydroxyacyl-CoA dehydrogenase;
8-187 3.29e-25

3-hydroxyacyl-CoA dehydrogenase;


Pssm-ID: 236434 [Multi-domain]  Cd Length: 288  Bit Score: 101.02  E-value: 3.29e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031   8 GVLKGALSAEQQ---LALISVCTDLKAAVEGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKLFTGLK 84
Cdd:PRK09260   51 GVARGKLTEAARqaaLARLSYSLDLKAAVADADLVIEAVPEKLELKKAVFETADAHAPAECYIATNTSTMSPTEIASFTK 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  85 HVKQCIVSHPVNPPYFVPLVEIVPHPETDPSTTERTYALMKKIGQSPVKLNrEIEGFVLNRLQYAVISEAWRLVGEGVIS 164
Cdd:PRK09260  131 RPERVIAMHFFNPVHKMKLVELIRGLETSDETVQVAKEVAEQMGKETVVVN-EFPGFVTSRISALVGNEAFYMLQEGVAT 209

                         170       180
                  ....*....|....*....|...
gi 1491393031 165 PTDLDLVMSdgLGMRYAfIGPLE 187
Cdd:PRK09260  210 AEDIDKAIR--LGLNFP-MGPLE 229
PRK08293 PRK08293
3-hydroxyacyl-CoA dehydrogenase;
15-189 3.56e-24

3-hydroxyacyl-CoA dehydrogenase;


Pssm-ID: 181359 [Multi-domain]  Cd Length: 287  Bit Score: 98.09  E-value: 3.56e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  15 SAEQQLALISVCTDLKAAVEGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKL--FTGlkHVKQCIVS 92
Cdd:PRK08293   64 PAEAALNRITLTTDLAEAVKDADLVIEAVPEDPEIKGDFYEELAKVAPEKTIFATNSSTLLPSQFaeATG--RPEKFLAL 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  93 HPVNPPYFVPLVEIVPHPETDPSTTERTYALMKKIGQSPVKLNREIEGFVLNRLQYAVISEAWRLVGEGVISPTDLDLVM 172
Cdd:PRK08293  142 HFANEIWKNNTAEIMGHPGTDPEVFDTVVAFAKAIGMVPIVLKKEQPGYILNSLLVPFLSAALALWAKGVADPETIDKTW 221

                         170
                  ....*....|....*..
gi 1491393031 173 SDGLGMRyafIGPLETM 189
Cdd:PRK08293  222 MIATGAP---MGPFGIL 235
PRK06035 PRK06035
3-hydroxyacyl-CoA dehydrogenase; Validated
 9-191 1.88e-19

3-hydroxyacyl-CoA dehydrogenase; Validated


Pssm-ID: 180361 [Multi-domain]  Cd Length: 291  Bit Score: 85.31  E-value: 1.88e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031   9 VLKGALS---AEQQLALISVCTDLkAAVEGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKLFTGLKH 85
Cdd:PRK06035   57 VEKGKMSedeAKAIMARIRTSTSY-ESLSDADFIVEAVPEKLDLKRKVFAELERNVSPETIIASNTSGIMIAEIATALER 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  86 VKQCIVSHPVNPPYFVPLVEIVPHPETDPSTTERTYALMKKIGQSPVKLNrEIEGFVLNRLQYAVISEAWRLVGEGVISP 165
Cdd:PRK06035  136 KDRFIGMHWFNPAPVMKLIEVVRAALTSEETFNTTVELSKKIGKIPIEVA-DVPGFFTTRFIEGWLLEAIRSFEIGIATI 214

                         170       180
                  ....*....|....*....|....*..
gi 1491393031 166 TDLDLVMSdglgMRYAF-IGPLETMHL 191
Cdd:PRK06035  215 KDIDEMCK----LAFGFpMGPFELMDI 237
PRK07819 PRK07819
3-hydroxybutyryl-CoA dehydrogenase; Validated
 4-186 4.60e-18

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 181133 [Multi-domain]  Cd Length: 286  Bit Score: 81.57  E-value: 4.60e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031   4 MEKS---GVLKGALS---AEQQLALISVCTDLkAAVEGATFIQECTPENLELKKKIFGQLDVIVGD-SVILSSSTSCLLP 76
Cdd:PRK07819   48 IEKSlerAVSRGKLTereRDAALARLRFTTDL-GDFADRQLVIEAVVEDEAVKTEIFAELDKVVTDpDAVLASNTSSIPI 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  77 SKLFTGLKHVKQCIVSHPVNPPYFVPLVEIVPHPETDPSTTERTYALMKKI-GQSPVKlNREIEGFVLNRLQYAVISEAW 155
Cdd:PRK07819  127 MKLAAATKRPGRVLGLHFFNPVPVLPLVELVPTLVTSEATVARAEEFASDVlGKQVVR-AQDRSGFVVNALLVPYLLSAI 205

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1491393031 156 RLVGEGVISPTDLDLVMSDGLG--MryafiGPL 186
Cdd:PRK07819  206 RMVESGFATAEDIDKAMVLGCAhpM-----GPL 233
3HCDH pfam00725
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda ...
 140-192 5.18e-16

3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda crystallin. Some proteins include two copies of this domain.


Pssm-ID: 395588 [Multi-domain]  Cd Length: 97  Bit Score: 71.48  E-value: 5.18e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1491393031 140 GFVLNRLQYAVISEAWRLVGEGVISPTDLDLVMSDGLGMRYAFIGPLETMHLN 192
Cdd:pfam00725   1 GFVVNRLLAPYLNEAIRLVEEGVATPEDIDAAMRLGLGLPMGPFELSDLVGLD 53
PRK07530 PRK07530
3-hydroxybutyryl-CoA dehydrogenase; Validated
 9-187 1.87e-12

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 181018 [Multi-domain]  Cd Length: 292  Bit Score: 65.80  E-value: 1.87e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031   9 VLKGALSAEQQ---LALISVCTDLkAAVEGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKLFTGLKH 85
Cdd:PRK07530   55 VAKGKISEEARaaaLARISTATDL-EDLADCDLVIEAATEDETVKRKIFAQLCPVLKPEAILATNTSSISITRLASATDR 133

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  86 VKQCIVSHPVNPpyfVP---LVEIVPHPETDPSTTERTYALMKKIGQSPVkLNREIEGFVLNRLQYAVISEAWRLVGEGV 162
Cdd:PRK07530  134 PERFIGIHFMNP---VPvmkLVELIRGIATDEATFEAAKEFVTKLGKTIT-VAEDFPAFIVNRILLPMINEAIYTLYEGV 209

                         170       180
                  ....*....|....*....|....*
gi 1491393031 163 ISPTDLDLVMSdgLGMRYAfIGPLE 187
Cdd:PRK07530  210 GSVEAIDTAMK--LGANHP-MGPLE 231
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
17-162 2.24e-12

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 66.46  E-value: 2.24e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  17 EQQLALISVCTDLKAaVEGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKLFTGLKHVKQCIVSHPVN 96
Cdd:PRK11154  372 DKQMALISGTTDYRG-FKHADVVIEAVFEDLALKQQMVAEVEQNCAPHTIFASNTSSLPIGQIAAAAARPEQVIGLHYFS 450

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1491393031  97 PPYFVPLVEIVPHPETDPSTTERTYALMKKIGQSPVKLnREIEGFVLNRLQYAVISEAWRLVGEGV 162
Cdd:PRK11154  451 PVEKMPLVEVIPHAKTSAETIATTVALAKKQGKTPIVV-RDGAGFYVNRILAPYINEAARLLLEGE 515
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 32-169 7.71e-10

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 59.08  E-value: 7.71e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031  32 AVEGATFIQECTPENLELKKKIFGQLDVIVGDSVILSSSTSCLLPSKLFTGLKHVKQCIVSHPVNPPYFVPLVEIVPHPE 111
Cdd:TIGR02441 411 GFKNADMVIEAVFEDLSLKHKVIKEVEAVVPPHCIIASNTSALPIKDIAAVSSRPEKVIGMHYFSPVDKMQLLEIITHDG 490

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1491393031 112 TDPSTTERTYALMKKIGQSPVKLnREIEGFVLNRLQYAVISEAWRLVGEGViSPTDLD 169
Cdd:TIGR02441 491 TSKDTLASAVAVGLKQGKVVIVV-KDGPGFYTTRCLGPMLAEVIRLLQEGV-DPKKLD 546
PRK08268 PRK08268
3-hydroxy-acyl-CoA dehydrogenase; Validated
 104-187 2.18e-03

3-hydroxy-acyl-CoA dehydrogenase; Validated


Pssm-ID: 236211 [Multi-domain]  Cd Length: 507  Bit Score: 39.06  E-value: 2.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491393031 104 VEIVPHPETDPSTTERTYALMKKIGQsPVKLNREIEGFVLNRLQYAVISEAWRLVGEGVISPTDLDLVMSDGLGmrYAFi 183
Cdd:PRK08268  381 RTLMAAPATSPAARDAAHALFQQDGK-AVSVIRDSPGFVAQRTVAMIVNEAADIAQQGIASPADIDLAMRLGLN--YPL- 456


                  ....
gi 1491393031 184 GPLE 187
Cdd:PRK08268  457 GPLA 460
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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