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Conserved domains on  [gi|1370474165|ref|XP_024307075|]
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SURP and G-patch domain-containing protein 2 isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SWAP smart00648
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ...
 799-852 7.00e-13

Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes


:

Pssm-ID: 197818 [Multi-domain]  Cd Length: 54  Bit Score: 64.15  E-value: 7.00e-13
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....
gi 1370474165   799 METAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDqNSSAFKFYRKKVFELC 852
Cdd:smart00648    1 LDIIDKTAQFVARNGPEFEAKLMERERNNPQFDFLKP-NDPYHAYYRKKLAEYR 53
G-patch pfam01585
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in ...
 1026-1057 1.33e-11

G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in proteins that contain RNA binding domains. This suggests that this domain may have an RNA binding function. This domain has seven highly conserved glycines.


:

Pssm-ID: 396249 [Multi-domain]  Cd Length: 45  Bit Score: 60.21  E-value: 1.33e-11
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1370474165 1026 KNLGFQMLQKMGWKEGHGLGSLGKGIREPVSV 1057
Cdd:pfam01585    2 SNIGFKLLQKMGWKEGQGLGKNEQGIAEPIEA 33
SWAP super family cl46999
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ...
 603-653 2.21e-04

Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes


The actual alignment was detected with superfamily member smart00648:

Pssm-ID: 197818 [Multi-domain]  Cd Length: 54  Bit Score: 39.88  E-value: 2.21e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....
gi 1370474165   603 TIDQLVKRVIEGSLSpKERTLL---KEDPAYWFLSDENSLeYKYYKLKLAEMQR 653
Cdd:smart00648    3 IIDKTAQFVARNGPE-FEAKLMereRNNPQFDFLKPNDPY-HAYYRKKLAEYRQ 54
 
Name Accession Description Interval E-value
SWAP smart00648
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ...
 799-852 7.00e-13

Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes


Pssm-ID: 197818 [Multi-domain]  Cd Length: 54  Bit Score: 64.15  E-value: 7.00e-13
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....
gi 1370474165   799 METAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDqNSSAFKFYRKKVFELC 852
Cdd:smart00648    1 LDIIDKTAQFVARNGPEFEAKLMERERNNPQFDFLKP-NDPYHAYYRKKLAEYR 53
Surp pfam01805
Surp module; This domain is also known as the SWAP domain. SWAP stands for ...
 800-850 8.40e-13

Surp module; This domain is also known as the SWAP domain. SWAP stands for Suppressor-of-White-APricot. It has been suggested that these domains may be RNA binding.


Pssm-ID: 460339 [Multi-domain]  Cd Length: 52  Bit Score: 63.69  E-value: 8.40e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1370474165  800 ETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFE 850
Cdd:pfam01805    1 DIIKKTAQFVARNGPEFEALLMEREERNPQFDFLFDPDDPLHAYYRWKLEE 51
G-patch pfam01585
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in ...
 1026-1057 1.33e-11

G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in proteins that contain RNA binding domains. This suggests that this domain may have an RNA binding function. This domain has seven highly conserved glycines.


Pssm-ID: 396249 [Multi-domain]  Cd Length: 45  Bit Score: 60.21  E-value: 1.33e-11
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1370474165 1026 KNLGFQMLQKMGWKEGHGLGSLGKGIREPVSV 1057
Cdd:pfam01585    2 SNIGFKLLQKMGWKEGQGLGKNEQGIAEPIEA 33
G_patch smart00443
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in ...
 1023-1066 2.04e-11

glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in the splicing factor 45, SON DNA binding protein and D-type Retrovirus- polyproteins.


Pssm-ID: 197727 [Multi-domain]  Cd Length: 47  Bit Score: 59.87  E-value: 2.04e-11
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1370474165  1023 LTDKNLGFQMLQKMGWKEGHGLGSLGKGIREPVSVYAA---GSLGWE 1066
Cdd:smart00443    1 ISTSNIGAKLLRKMGWKEGQGLGKNEQGIVEPISAEIKkdrKGLGAV 47
SWAP smart00648
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ...
 603-653 2.21e-04

Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes


Pssm-ID: 197818 [Multi-domain]  Cd Length: 54  Bit Score: 39.88  E-value: 2.21e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....
gi 1370474165   603 TIDQLVKRVIEGSLSpKERTLL---KEDPAYWFLSDENSLeYKYYKLKLAEMQR 653
Cdd:smart00648    3 IIDKTAQFVARNGPE-FEAKLMereRNNPQFDFLKPNDPY-HAYYRKKLAEYRQ 54
Surp pfam01805
Surp module; This domain is also known as the SWAP domain. SWAP stands for ...
 602-651 6.39e-04

Surp module; This domain is also known as the SWAP domain. SWAP stands for Suppressor-of-White-APricot. It has been suggested that these domains may be RNA binding.


Pssm-ID: 460339 [Multi-domain]  Cd Length: 52  Bit Score: 38.65  E-value: 6.39e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1370474165  602 GTIDQLVKRVIEGSLSPKERTLLKE--DPAYWFLSDENSLEYKYYKLKLAEM 651
Cdd:pfam01805    1 DIIKKTAQFVARNGPEFEALLMEREerNPQFDFLFDPDDPLHAYYRWKLEEY 52
 
Name Accession Description Interval E-value
SWAP smart00648
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ...
 799-852 7.00e-13

Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes


Pssm-ID: 197818 [Multi-domain]  Cd Length: 54  Bit Score: 64.15  E-value: 7.00e-13
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....
gi 1370474165   799 METAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDqNSSAFKFYRKKVFELC 852
Cdd:smart00648    1 LDIIDKTAQFVARNGPEFEAKLMERERNNPQFDFLKP-NDPYHAYYRKKLAEYR 53
Surp pfam01805
Surp module; This domain is also known as the SWAP domain. SWAP stands for ...
 800-850 8.40e-13

Surp module; This domain is also known as the SWAP domain. SWAP stands for Suppressor-of-White-APricot. It has been suggested that these domains may be RNA binding.


Pssm-ID: 460339 [Multi-domain]  Cd Length: 52  Bit Score: 63.69  E-value: 8.40e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1370474165  800 ETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFE 850
Cdd:pfam01805    1 DIIKKTAQFVARNGPEFEALLMEREERNPQFDFLFDPDDPLHAYYRWKLEE 51
G-patch pfam01585
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in ...
 1026-1057 1.33e-11

G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in proteins that contain RNA binding domains. This suggests that this domain may have an RNA binding function. This domain has seven highly conserved glycines.


Pssm-ID: 396249 [Multi-domain]  Cd Length: 45  Bit Score: 60.21  E-value: 1.33e-11
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1370474165 1026 KNLGFQMLQKMGWKEGHGLGSLGKGIREPVSV 1057
Cdd:pfam01585    2 SNIGFKLLQKMGWKEGQGLGKNEQGIAEPIEA 33
G_patch smart00443
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in ...
 1023-1066 2.04e-11

glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in the splicing factor 45, SON DNA binding protein and D-type Retrovirus- polyproteins.


Pssm-ID: 197727 [Multi-domain]  Cd Length: 47  Bit Score: 59.87  E-value: 2.04e-11
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1370474165  1023 LTDKNLGFQMLQKMGWKEGHGLGSLGKGIREPVSVYAA---GSLGWE 1066
Cdd:smart00443    1 ISTSNIGAKLLRKMGWKEGQGLGKNEQGIVEPISAEIKkdrKGLGAV 47
SWAP smart00648
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ...
 603-653 2.21e-04

Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes


Pssm-ID: 197818 [Multi-domain]  Cd Length: 54  Bit Score: 39.88  E-value: 2.21e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....
gi 1370474165   603 TIDQLVKRVIEGSLSpKERTLL---KEDPAYWFLSDENSLeYKYYKLKLAEMQR 653
Cdd:smart00648    3 IIDKTAQFVARNGPE-FEAKLMereRNNPQFDFLKPNDPY-HAYYRKKLAEYRQ 54
Surp pfam01805
Surp module; This domain is also known as the SWAP domain. SWAP stands for ...
 602-651 6.39e-04

Surp module; This domain is also known as the SWAP domain. SWAP stands for Suppressor-of-White-APricot. It has been suggested that these domains may be RNA binding.


Pssm-ID: 460339 [Multi-domain]  Cd Length: 52  Bit Score: 38.65  E-value: 6.39e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1370474165  602 GTIDQLVKRVIEGSLSPKERTLLKE--DPAYWFLSDENSLEYKYYKLKLAEM 651
Cdd:pfam01805    1 DIIKKTAQFVARNGPEFEALLMEREerNPQFDFLFDPDDPLHAYYRWKLEEY 52
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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