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Conserved domains on  [gi|1370454402|ref|XP_024305232|]
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C4b-binding protein beta chain isoform X2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 46-207 1.06e-16

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 77.00  E-value: 1.06e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454402  46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT 125
Cdd:PHA02927   52 YLCLPGYRKQKMGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCELGST 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454402 126 ----WAPPFPICKSRDCDPPGNPVHGYFEGNN--FTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSAlPVCKLIQeAPKP 199
Cdd:PHA02927  132 gsmvWNPEAPICESVKCQSPPSISNGRHNGYEdfYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDP-PTCQIVK-CPHP 209


                  ....*...
gi 1370454402 200 ECEKALLA 207
Cdd:PHA02927  210 TISNGYLS 217
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 46-207 1.06e-16

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 77.00  E-value: 1.06e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454402  46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT 125
Cdd:PHA02927   52 YLCLPGYRKQKMGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCELGST 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454402 126 ----WAPPFPICKSRDCDPPGNPVHGYFEGNN--FTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSAlPVCKLIQeAPKP 199
Cdd:PHA02927  132 gsmvWNPEAPICESVKCQSPPSISNGRHNGYEdfYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDP-PTCQIVK-CPHP 209


                  ....*...
gi 1370454402 200 ECEKALLA 207
Cdd:PHA02927  210 TISNGYLS 217
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 80-134 2.82e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.78  E-value: 2.82e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370454402  80 CPDP-VLVNGEFS-SSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICK 134
Cdd:cd00033     1 CPPPpVPENGTVTgSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
138-190 8.27e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 53.27  E-value: 8.27e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370454402 138 CDPPGNPVHGYFEG--NNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 190
Cdd:pfam00084   1 CPPPPDIPNGKVSAtkNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 80-133 2.19e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.14  E-value: 2.19e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370454402   80 CPDP-VLVNGEF-SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC 133
Cdd:smart00032   1 CPPPpDIENGTVtSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 46-207 1.06e-16

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 77.00  E-value: 1.06e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454402  46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT 125
Cdd:PHA02927   52 YLCLPGYRKQKMGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCELGST 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454402 126 ----WAPPFPICKSRDCDPPGNPVHGYFEGNN--FTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSAlPVCKLIQeAPKP 199
Cdd:PHA02927  132 gsmvWNPEAPICESVKCQSPPSISNGRHNGYEdfYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDP-PTCQIVK-CPHP 209


                  ....*...
gi 1370454402 200 ECEKALLA 207
Cdd:PHA02927  210 TISNGYLS 217
PHA02639 PHA02639
EEV host range protein; Provisional
 46-190 7.68e-15

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 72.39  E-value: 7.68e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454402  46 YVCIKGYHLVGKKTLFCNASKE---WDNTTTECRLGHCPDP-VLVNGE-FSSSGPVNVSDKITFMCNDH----YILKGSN 116
Cdd:PHA02639   48 YTCNTDYALIGDRFRTCIKDKNnaiWSNKAPFCMLKECNDPpSIINGKiYNKREMYKVGDEIYYVCNEHkgvqYSLVGNE 127

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370454402 117 RSQCLEDHTWAPPFPICKSRDCDPPGNPvHGYFEG----NNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
Cdd:PHA02639  128 KITCIQDKSWKPDPPICKMINCRFPALQ-NGYINGipsnKKFYYKTRVGFSCKSGFDLVGEKYSTCnINATWFPSIPTC 205
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 22-133 1.30e-13

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 68.53  E-value: 1.30e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454402  22 CPELPPVDNSIFVAKE---VEGQILgTYVCIKGYHLVGKKTLFCNASkEWDNTTTeCRLGHCPDPVLVNGEFSSSGPVNV 98
Cdd:PHA02927  148 CQSPPSISNGRHNGYEdfyTDGSVV-TYSCNSGYSLIGNSGVLCSGG-EWSDPPT-CQIVKCPHPTISNGYLSSGFKRSY 224

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1370454402  99 S--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC 133
Cdd:PHA02927  225 SynDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKC 261
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 80-134 2.82e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.78  E-value: 2.82e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370454402  80 CPDP-VLVNGEFS-SSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICK 134
Cdd:cd00033     1 CPPPpVPENGTVTgSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 138-191 3.18e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.39  E-value: 3.18e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370454402 138 CDPPGNPVHGYFEG--NNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCK 191
Cdd:cd00033     1 CPPPPVPENGTVTGskGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
138-190 8.27e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 53.27  E-value: 8.27e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370454402 138 CDPPGNPVHGYFEG--NNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 190
Cdd:pfam00084   1 CPPPPDIPNGKVSAtkNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 80-133 2.19e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.14  E-value: 2.19e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370454402   80 CPDP-VLVNGEF-SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC 133
Cdd:smart00032   1 CPPPpDIENGTVtSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 138-190 2.32e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.14  E-value: 2.32e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370454402  138 CDPPGNPVHGYFEG--NNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 190
Cdd:smart00032   1 CPPPPDIENGTVTSssGTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 22-190 3.20e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 55.81  E-value: 3.20e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454402  22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFC----NASKEWDNTTTECRLGHCPD-PVLVNG------EF 90
Cdd:PHA02927   86 CPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCelgsTGSMVWNPEAPICESVKCQSpPSISNGrhngyeDF 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454402  91 SSSGPVnvsdkITFMCNDHYILKGSNRSQClEDHTWAPPfPICKSRDCDPPgNPVHGYFEGN---NFTLGSTISYYCEDR 167
Cdd:PHA02927  166 YTDGSV-----VTYSCNSGYSLIGNSGVLC-SGGEWSDP-PTCQIVKCPHP-TISNGYLSSGfkrSYSYNDNVDFKCKYG 237

                         170       180
                  ....*....|....*....|....
gi 1370454402 168 YYLVGVQEQQCVDGE-WSSALPVC 190
Cdd:PHA02927  238 YKLSGSSSSTCSPGNtWQPELPKC 261
PHA02817 PHA02817
EEV Host range protein; Provisional
 80-190 2.35e-08

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 53.02  E-value: 2.35e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454402  80 CPDPVLVNGEFSSSGPV-NVSDKITFMCNDH-----YILKGSNRSQCLEDHTWAPPFPICKSRDCDPPG---NPVHGYFE 150
Cdd:PHA02817   25 CYPPSIKNGYIYNKKTEyNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCKIIRCRFPAlqnGFVNGIPD 104

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1370454402 151 GNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
Cdd:PHA02817  105 SKKFYYESEVSFSCKPGFVLIGTKYSVCgINSSWIPKVPIC 145
PHA02817 PHA02817
EEV Host range protein; Provisional
 52-137 3.48e-08

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 52.64  E-value: 3.48e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454402  52 YHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFS---SSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAP 128
Cdd:PHA02817   61 YTLVGEKNIICEKDGKWNKEFPVCKIIRCRFPALQNGFVNgipDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIP 140


                  ....*....
gi 1370454402 129 PFPICKSRD 137
Cdd:PHA02817  141 KVPICSRDN 149
Sushi pfam00084
Sushi repeat (SCR repeat);
80-133 2.07e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 46.72  E-value: 2.07e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370454402  80 CPDP-VLVNGEFSSS-GPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC 133
Cdd:pfam00084   1 CPPPpDIPNGKVSATkNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 102-193 4.01e-07

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 50.05  E-value: 4.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454402 102 ITFMCNDHYILKGSNRSQCLEDHT---WAPPFPICKSRDCDPPGNPVHG--YFEGNNFTLGSTISYYCED----RYYLVG 172
Cdd:PHA02639   46 IEYTCNTDYALIGDRFRTCIKDKNnaiWSNKAPFCMLKECNDPPSIINGkiYNKREMYKVGDEIYYVCNEhkgvQYSLVG 125

                          90       100
                  ....*....|....*....|..
gi 1370454402 173 VQEQQCV-DGEWSSALPVCKLI 193
Cdd:PHA02639  126 NEKITCIqDKSWKPDPPICKMI 147
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 63-199 7.99e-07

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 49.31  E-value: 7.99e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454402  63 NASKEWDNTTTeCRLGHCPDPVLVNGefsSSGPV----NVSDKITFMCNDHYILKGSNRSQCLEDhTWAPpFPICKSRdC 138
Cdd:PHA02954  114 NGNTSWNDTVT-CPNAECQPLQLEHG---SCQPVkekySFGEHITINCDVGYEVIGASYISCTAN-SWNV-IPSCQQK-C 186

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370454402 139 DPPgNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSALPVCKLIQEAPKP 199
Cdd:PHA02954  187 DIP-SLSNGLISGSTFSIGGVIHLSCKSGFTLTGSPSSTCIDGKWNPVLPICVRSNEEFDP 246
PHA02831 PHA02831
EEV host range protein; Provisional
 136-194 2.48e-06

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 47.29  E-value: 2.48e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370454402 136 RDCDPPGNPVHGYFEG--NNFTLGSTISYYCE----DRYYLVGVQEQQCVDGEWSSALPVCKLIQ 194
Cdd:PHA02831   76 RNCKDPVTILNGYIKNkkDQYSFGDSVTYACKvnklEKYSIVGNETVKCINKQWVPKYPVCKLIR 140
PHA02831 PHA02831
EEV host range protein; Provisional
 45-133 3.87e-06

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 46.91  E-value: 3.87e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454402  45 TYVC----IKGYHLVGKKTLFCnASKEWDNTTTECRLGHCPDPVLVNGEFSS-SGPVNVSDKITFMCNDHYILKGSNRSQ 119
Cdd:PHA02831  103 TYACkvnkLEKYSIVGNETVKC-INKQWVPKYPVCKLIRCKYPALQNGFLNVfEKKFYYGDIVNFKCKKGFILLGSSVST 181

                          90
                  ....*....|....
gi 1370454402 120 CLEDHTWAPPFPIC 133
Cdd:PHA02831  182 CDINSIWYPGIPKC 195
PHA02831 PHA02831
EEV host range protein; Provisional
 79-190 4.41e-06

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 46.52  E-value: 4.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454402  79 HCPDPVLV-NGEFSS-SGPVNVSDKITFMCN----DHYILKGSNRSQCLeDHTWAPPFPICKSRDCDPPG--NPVHGYFE 150
Cdd:PHA02831   77 NCKDPVTIlNGYIKNkKDQYSFGDSVTYACKvnklEKYSIVGNETVKCI-NKQWVPKYPVCKLIRCKYPAlqNGFLNVFE 155

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1370454402 151 gNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
Cdd:PHA02831  156 -KKFYYGDIVNFKCKKGFILLGSSVSTCdINSIWYPGIPKC 195
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 22-76 4.91e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 42.84  E-value: 4.91e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1370454402  22 CPELPPVDNSIFV---AKEVEGQILgTYVCIKGYHLVGKKTLFCNASKEWDNTTTECR 76
Cdd:cd00033     1 CPPPPVPENGTVTgskGSYSYGSTV-TYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 22-75 1.70e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 41.36  E-value: 1.70e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370454402   22 CPELPPVDNSIFVAKE---VEGQILgTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC 75
Cdd:smart00032   1 CPPPPDIENGTVTSSSgtySYGDTV-TYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 97-199 4.28e-04

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 40.79  E-value: 4.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454402  97 NVSDKITFMCNDHYILK--GSNRSQClEDHTWAPpFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQ 174
Cdd:PHA02927   45 NIGDTIEYLCLPGYRKQkmGPIYAKC-TGTGWTL-FNQCIKRRCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGES 122

                          90       100       110
                  ....*....|....*....|....*....|
gi 1370454402 175 EQQCVDGE-----WSSALPVCKLIQEAPKP 199
Cdd:PHA02927  123 KSYCELGStgsmvWNPEAPICESVKCQSPP 152
PHA02817 PHA02817
EEV Host range protein; Provisional
 133-193 2.81e-03

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 38.00  E-value: 2.81e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370454402 133 CKSRDCDPPGNPVHGYF--EGNNFTLGSTISYYCED-----RYYLVGVQEQQC-VDGEWSSALPVCKLI 193
Cdd:PHA02817   19 CDLNKCCYPPSIKNGYIynKKTEYNIGSNVTFFCGNntrgvRYTLVGEKNIICeKDGKWNKEFPVCKII 87
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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