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Conserved domains on  [gi|1370513696|ref|XP_024303166|]
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calcium channel flower homolog isoform X2 [Homo sapiens]

Protein Classification

Tvp18 family protein( domain architecture ID 10660845)

Tvp18 family protein such as Tvp18 Golgi membrane proteins that are involved in vesicular trafficking and the calcium channel flower proteins, which form calcium channels that regulate synaptic endocytosis

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Cg6151-P smart01077
Uncharacterized conserved protein CG6151-P; This is a family of small, less than 200 residue ...
1-80 4.65e-32

Uncharacterized conserved protein CG6151-P; This is a family of small, less than 200 residue long, proteins which are named as CG6151-P proteins that are conserved from fungi to humans. The function is unknown. The fungal members have a characteristic ICP sequence motif. Some members are annotated as putative clathrin-coated vesicle protein but this could not be defined.


:

Pssm-ID: 198145  Cd Length: 111  Bit Score: 110.81  E-value: 4.65e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370513696    1 MIMNAFILLLCEAPFCCQFIEFANTVAEKVDRLRS-WQKAVFYCGMAVVPIVISLTLTTLLGNAIAFA-TGVLYGLSALG 78
Cdd:smart01077  30 MIVQGFVLLFIEAPFLLKICPFSDKFAEFIDKFDTnWQRAAFYCGMAIVPILSCIMLTSLLGVAIFFAiTGVCYGLAALG 109

                   ..
gi 1370513696   79 KK 80
Cdd:smart01077 110 KQ 111
 
Name Accession Description Interval E-value
Cg6151-P smart01077
Uncharacterized conserved protein CG6151-P; This is a family of small, less than 200 residue ...
1-80 4.65e-32

Uncharacterized conserved protein CG6151-P; This is a family of small, less than 200 residue long, proteins which are named as CG6151-P proteins that are conserved from fungi to humans. The function is unknown. The fungal members have a characteristic ICP sequence motif. Some members are annotated as putative clathrin-coated vesicle protein but this could not be defined.


Pssm-ID: 198145  Cd Length: 111  Bit Score: 110.81  E-value: 4.65e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370513696    1 MIMNAFILLLCEAPFCCQFIEFANTVAEKVDRLRS-WQKAVFYCGMAVVPIVISLTLTTLLGNAIAFA-TGVLYGLSALG 78
Cdd:smart01077  30 MIVQGFVLLFIEAPFLLKICPFSDKFAEFIDKFDTnWQRAAFYCGMAIVPILSCIMLTSLLGVAIFFAiTGVCYGLAALG 109

                   ..
gi 1370513696   79 KK 80
Cdd:smart01077 110 KQ 111
Cg6151-P pfam10233
Uncharacterized conserved protein CG6151-P; This is a family of small, less than 200 residue ...
1-80 2.94e-24

Uncharacterized conserved protein CG6151-P; This is a family of small, less than 200 residue long, proteins which are named as CG6151-P proteins that are conserved from fungi to humans. The function is unknown. The fungal members have a characteriztic ICP sequence motif. Some members are annotated as putative clathrin-coated vesicle protein but this could not be defined.


Pssm-ID: 431157  Cd Length: 113  Bit Score: 91.05  E-value: 2.94e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370513696   1 MIMNAFILLLCEAPFCCQFIEFANTVAEKVDRL-RSWQKAVFYCGMAVVP--IVISLTLTTLLGNAIAFATGVLYGLSAL 77
Cdd:pfam10233  31 CIVSGFIVLFIEVPFLLRICPTSDKFDAFIRKFeTNWMRAAFYLVMAVVQwlSLCVFATSLIAGAVLLFITGVCYGLAAL 110

                  ...
gi 1370513696  78 GKK 80
Cdd:pfam10233 111 GKQ 113
 
Name Accession Description Interval E-value
Cg6151-P smart01077
Uncharacterized conserved protein CG6151-P; This is a family of small, less than 200 residue ...
1-80 4.65e-32

Uncharacterized conserved protein CG6151-P; This is a family of small, less than 200 residue long, proteins which are named as CG6151-P proteins that are conserved from fungi to humans. The function is unknown. The fungal members have a characteristic ICP sequence motif. Some members are annotated as putative clathrin-coated vesicle protein but this could not be defined.


Pssm-ID: 198145  Cd Length: 111  Bit Score: 110.81  E-value: 4.65e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370513696    1 MIMNAFILLLCEAPFCCQFIEFANTVAEKVDRLRS-WQKAVFYCGMAVVPIVISLTLTTLLGNAIAFA-TGVLYGLSALG 78
Cdd:smart01077  30 MIVQGFVLLFIEAPFLLKICPFSDKFAEFIDKFDTnWQRAAFYCGMAIVPILSCIMLTSLLGVAIFFAiTGVCYGLAALG 109

                   ..
gi 1370513696   79 KK 80
Cdd:smart01077 110 KQ 111
Cg6151-P pfam10233
Uncharacterized conserved protein CG6151-P; This is a family of small, less than 200 residue ...
1-80 2.94e-24

Uncharacterized conserved protein CG6151-P; This is a family of small, less than 200 residue long, proteins which are named as CG6151-P proteins that are conserved from fungi to humans. The function is unknown. The fungal members have a characteriztic ICP sequence motif. Some members are annotated as putative clathrin-coated vesicle protein but this could not be defined.


Pssm-ID: 431157  Cd Length: 113  Bit Score: 91.05  E-value: 2.94e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370513696   1 MIMNAFILLLCEAPFCCQFIEFANTVAEKVDRL-RSWQKAVFYCGMAVVP--IVISLTLTTLLGNAIAFATGVLYGLSAL 77
Cdd:pfam10233  31 CIVSGFIVLFIEVPFLLRICPTSDKFDAFIRKFeTNWMRAAFYLVMAVVQwlSLCVFATSLIAGAVLLFITGVCYGLAAL 110

                  ...
gi 1370513696  78 GKK 80
Cdd:pfam10233 111 GKQ 113
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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