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cyclin-D-binding Myb-like transcription factor 1 isoform X1 [Homo sapiens]
cyclin-D-binding Myb-like transcription factor 1( domain architecture ID 13419776)
cyclin-D-binding Myb-like transcription factor 1 (DMTF1) is a transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53-dependent growth arrest
List of domain hits
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Name | Accession | Description | Interval | E-value | ||||||
DMTF1_N | pfam20588 | Cyclin-D-binding Myb-like transcription factor 1 N-terminal; This domain is found at the ... |
80-158 | 1.23e-22 | ||||||
Cyclin-D-binding Myb-like transcription factor 1 N-terminal; This domain is found at the N-terminal of Cyclin-D-binding Myb-like transcription factor 1 (DMTF1), which is rich in acidic residues, adjacent pfam00249. DMTF1 is a tumour suppressor that interacts with and activates CDKN2A/ARF in response to Ras-Raf signalling, thus inducing p53-dependent cell cycle arrest. : Pssm-ID: 466737 Cd Length: 72 Bit Score: 92.10 E-value: 1.23e-22
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Myb_DNA-binding | pfam00249 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
274-329 | 1.50e-11 | ||||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. : Pssm-ID: 459731 [Multi-domain] Cd Length: 46 Bit Score: 59.44 E-value: 1.50e-11
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Myb_DNA-bind_6 | pfam13921 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
228-284 | 4.67e-10 | ||||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. : Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 55.78 E-value: 4.67e-10
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REB1 super family | cl34920 | Myb superfamily proteins, including transcription factors and mRNA splicing factors ... |
89-438 | 2.09e-08 | ||||||
Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning]; The actual alignment was detected with superfamily member COG5147: Pssm-ID: 227476 [Multi-domain] Cd Length: 512 Bit Score: 57.49 E-value: 2.09e-08
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Name | Accession | Description | Interval | E-value | ||||||
DMTF1_N | pfam20588 | Cyclin-D-binding Myb-like transcription factor 1 N-terminal; This domain is found at the ... |
80-158 | 1.23e-22 | ||||||
Cyclin-D-binding Myb-like transcription factor 1 N-terminal; This domain is found at the N-terminal of Cyclin-D-binding Myb-like transcription factor 1 (DMTF1), which is rich in acidic residues, adjacent pfam00249. DMTF1 is a tumour suppressor that interacts with and activates CDKN2A/ARF in response to Ras-Raf signalling, thus inducing p53-dependent cell cycle arrest. Pssm-ID: 466737 Cd Length: 72 Bit Score: 92.10 E-value: 1.23e-22
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Myb_DNA-binding | pfam00249 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
274-329 | 1.50e-11 | ||||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 459731 [Multi-domain] Cd Length: 46 Bit Score: 59.44 E-value: 1.50e-11
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Myb_DNA-bind_6 | pfam13921 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
228-284 | 4.67e-10 | ||||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 55.78 E-value: 4.67e-10
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SANT | cd00167 | 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
275-329 | 4.74e-10 | ||||||
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA. Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 55.27 E-value: 4.74e-10
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SANT | smart00717 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
274-330 | 6.97e-10 | ||||||
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 54.92 E-value: 6.97e-10
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REB1 | COG5147 | Myb superfamily proteins, including transcription factors and mRNA splicing factors ... |
89-438 | 2.09e-08 | ||||||
Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning]; Pssm-ID: 227476 [Multi-domain] Cd Length: 512 Bit Score: 57.49 E-value: 2.09e-08
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SANT | smart00717 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
225-270 | 6.75e-07 | ||||||
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 46.45 E-value: 6.75e-07
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SANT | cd00167 | 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
226-268 | 8.43e-07 | ||||||
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA. Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 46.03 E-value: 8.43e-07
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SANT | smart00717 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
336-389 | 3.39e-04 | ||||||
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 38.74 E-value: 3.39e-04
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SANT | cd00167 | 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
338-388 | 2.86e-03 | ||||||
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA. Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 36.01 E-value: 2.86e-03
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Name | Accession | Description | Interval | E-value | ||||||
DMTF1_N | pfam20588 | Cyclin-D-binding Myb-like transcription factor 1 N-terminal; This domain is found at the ... |
80-158 | 1.23e-22 | ||||||
Cyclin-D-binding Myb-like transcription factor 1 N-terminal; This domain is found at the N-terminal of Cyclin-D-binding Myb-like transcription factor 1 (DMTF1), which is rich in acidic residues, adjacent pfam00249. DMTF1 is a tumour suppressor that interacts with and activates CDKN2A/ARF in response to Ras-Raf signalling, thus inducing p53-dependent cell cycle arrest. Pssm-ID: 466737 Cd Length: 72 Bit Score: 92.10 E-value: 1.23e-22
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Myb_DNA-binding | pfam00249 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
274-329 | 1.50e-11 | ||||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 459731 [Multi-domain] Cd Length: 46 Bit Score: 59.44 E-value: 1.50e-11
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Myb_DNA-bind_6 | pfam13921 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
228-284 | 4.67e-10 | ||||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 55.78 E-value: 4.67e-10
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SANT | cd00167 | 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
275-329 | 4.74e-10 | ||||||
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA. Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 55.27 E-value: 4.74e-10
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SANT | smart00717 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
274-330 | 6.97e-10 | ||||||
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 54.92 E-value: 6.97e-10
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Myb_DNA-binding | pfam00249 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
225-268 | 1.82e-08 | ||||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 459731 [Multi-domain] Cd Length: 46 Bit Score: 50.97 E-value: 1.82e-08
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REB1 | COG5147 | Myb superfamily proteins, including transcription factors and mRNA splicing factors ... |
89-438 | 2.09e-08 | ||||||
Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning]; Pssm-ID: 227476 [Multi-domain] Cd Length: 512 Bit Score: 57.49 E-value: 2.09e-08
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Myb_DNA-bind_6 | pfam13921 | Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
276-347 | 2.80e-07 | ||||||
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family. Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 48.08 E-value: 2.80e-07
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SANT | smart00717 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
225-270 | 6.75e-07 | ||||||
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 46.45 E-value: 6.75e-07
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SANT | cd00167 | 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
226-268 | 8.43e-07 | ||||||
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA. Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 46.03 E-value: 8.43e-07
|
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SANT | smart00717 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
336-389 | 3.39e-04 | ||||||
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 38.74 E-value: 3.39e-04
|
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SANT | cd00167 | 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
338-388 | 2.86e-03 | ||||||
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA. Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 36.01 E-value: 2.86e-03
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Myb_DNA-bind_4 | pfam13837 | Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb ... |
275-327 | 3.99e-03 | ||||||
Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT-like DNA binding domains. In particular pfam10545 seems most related. This family is greatly expanded in plants and appears in several proteins annotated as transposon proteins. Pssm-ID: 463994 Cd Length: 84 Bit Score: 36.86 E-value: 3.99e-03
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REB1 | COG5147 | Myb superfamily proteins, including transcription factors and mRNA splicing factors ... |
274-443 | 8.43e-03 | ||||||
Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning]; Pssm-ID: 227476 [Multi-domain] Cd Length: 512 Bit Score: 39.39 E-value: 8.43e-03
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Blast search parameters | ||||
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