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Conserved domains on  [gi|1348555408|ref|XP_023994385|]
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zinc finger protein 26-like [Salvelinus alpinus]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11473500)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11179890|12665246|10940247|11361095|22803940
SCOP:  4003583

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
672-863 8.29e-07

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 53.16  E-value: 8.29e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  672 AKLMQDWSRTPLPHVCPHCGQTFTRRGFLRAHVFSHTGEKL-FTCKVCQKSFASSPNLLRH----SLTHMGTKPFPC--S 744
Cdd:COG5048    248 LSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLpIKSKQCNISFSRSSPLTRHlrsvNHSGESLKPFSCpyS 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  745 VCGKRFSQPGVLKRHGLTHSQPKSRRRRSRWKKRTPEGEDGE--------------SQLFAC--PNCTARFQTDQQLQEH 808
Cdd:COG5048    328 LCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqqykdlknDKKSETlsNSCIRNFKRDSNLSLH 407

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1348555408  809 RLLH---TSHPFPCSVCGEAFKRRKELDLHSLIHQDKEPVLCphCSSQFLNQSVLDIH 863
Cdd:COG5048    408 IITHlsfRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLC--SILKSFRRDLDLSN 463
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 298-366 9.15e-06

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 50.32  E-value: 9.15e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1348555408  298 AQSAADRQSIPDPAPSQDPPDPA----------PSQDPPDRAPSqDPQDSAPSQDPPDPAlsqdPPDPVPSqDPPADNP 366
Cdd:PHA03247  2559 APPAAPDRSVPPPRPAPRPSEPAvtsrarrpdaPPQSARPRAPV-DDRGDPRGPAPPSPL----PPDTHAP-DPPPPSP 2631
zf-H2C2_2 pfam13465
Zinc-finger double domain;
975-996 3.11e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 3.11e-04
                           10        20
                   ....*....|....*....|..
gi 1348555408  975 HMRIHTDERPFECSTCGKRFRQ 996
Cdd:pfam13465    5 HMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
999-1023 7.38e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 7.38e-04
                           10        20
                   ....*....|....*....|....*
gi 1348555408  999 HLKDHERIHSGLRPFCCWVCGKAFS 1023
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 1041-1063 4.74e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


:

Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 35.74  E-value: 4.74e-03
                           10        20
                   ....*....|....*....|...
gi 1348555408 1041 YTCHHCPSAFRSRSNLDKHIRLH 1063
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
672-863 8.29e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 53.16  E-value: 8.29e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  672 AKLMQDWSRTPLPHVCPHCGQTFTRRGFLRAHVFSHTGEKL-FTCKVCQKSFASSPNLLRH----SLTHMGTKPFPC--S 744
Cdd:COG5048    248 LSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLpIKSKQCNISFSRSSPLTRHlrsvNHSGESLKPFSCpyS 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  745 VCGKRFSQPGVLKRHGLTHSQPKSRRRRSRWKKRTPEGEDGE--------------SQLFAC--PNCTARFQTDQQLQEH 808
Cdd:COG5048    328 LCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqqykdlknDKKSETlsNSCIRNFKRDSNLSLH 407

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1348555408  809 RLLH---TSHPFPCSVCGEAFKRRKELDLHSLIHQDKEPVLCphCSSQFLNQSVLDIH 863
Cdd:COG5048    408 IITHlsfRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLC--SILKSFRRDLDLSN 463
PHA03247 PHA03247
large tegument protein UL36; Provisional
 298-366 9.15e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 50.32  E-value: 9.15e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1348555408  298 AQSAADRQSIPDPAPSQDPPDPA----------PSQDPPDRAPSqDPQDSAPSQDPPDPAlsqdPPDPVPSqDPPADNP 366
Cdd:PHA03247  2559 APPAAPDRSVPPPRPAPRPSEPAvtsrarrpdaPPQSARPRAPV-DDRGDPRGPAPPSPL----PPDTHAP-DPPPPSP 2631
zf-H2C2_2 pfam13465
Zinc-finger double domain;
727-752 7.96e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.82  E-value: 7.96e-05
                           10        20
                   ....*....|....*....|....*.
gi 1348555408  727 NLLRHSLTHMGTKPFPCSVCGKRFSQ 752
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
FAP pfam07174
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment ...
 291-367 1.07e-04

Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment proteins (FAP). Family members are rich in alanine and proline, are approximately 300 long, and seem to be restricted to mycobacteria. These proteins contain a fibronectin-binding motif that allows mycobacteria to bind to fibronectin in the extracellular matrix.


Pssm-ID: 429334  Cd Length: 301  Bit Score: 45.69  E-value: 1.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  291 AAHSSTEAQSAADRQSIPDPAPSQDPPDPAPSQDPPdraPSQDPQDSAPSQDPPDPALSQDPP-DP----VPSQDPPADN 365
Cdd:pfam07174   36 VAHADPEPAPPPPSTATAPPAPPPPPPAPAAPAPPP---PPAAPNAPNAPPPPADPNAPPPPPaDPnappPPAVDPNAPE 112


                   ..
gi 1348555408  366 PG 367
Cdd:pfam07174  113 PG 114
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 283-375 2.10e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 45.39  E-value: 2.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  283 KASEIQAQAAHSSTEAQSAADRqsiPDPAPSQDPPDPAPSQDPPDRAPS-------QDPQDSAP-SQDPPDPALSQDPPD 354
Cdd:NF033838   398 AEEEAKRKAAEEDKVKEKPAEQ---PQPAPAPQPEKPAPKPEKPAEQPKaekpadqQAEEDYARrSEEEYNRLTQQQPPK 474

                           90       100
                   ....*....|....*....|....
gi 1348555408  355 PVPSQDPPADNPGEEQTS---YYY 375
Cdd:NF033838   475 TEKPAQPSTPKTGWKQENgmwYFY 498
zf-H2C2_2 pfam13465
Zinc-finger double domain;
975-996 3.11e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 3.11e-04
                           10        20
                   ....*....|....*....|..
gi 1348555408  975 HMRIHTDERPFECSTCGKRFRQ 996
Cdd:pfam13465    5 HMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
999-1023 7.38e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 7.38e-04
                           10        20
                   ....*....|....*....|....*
gi 1348555408  999 HLKDHERIHSGLRPFCCWVCGKAFS 1023
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFK 25
KREPA2 cd23959
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of ...
 288-415 2.04e-03

Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of the parasitic protozoan's KREPA RNA editing catalytic complex (RECC). Kinetoplastid RNA editing (KRE) proteins occur as pairs or sets of related proteins in multiple complexes. KREPA complex is composed of six components (KREPA1-6), which share a conserved C-terminal region containing an oligonucleotide-binding (OB)-fold-like domain. KREPAs are responsible for the site-specific insertion and deletion of U nucleotides in the kinetoplastid mitochondria pre-messenger RNA. Apart from the conserved C-terminal OB-fold domain, KREPA1, KREPA2, and KREPA3 contain two conserved C2H2 zinc-finger domains. KREPA2 and kinetoplastid RNA editing ligase 1 (KREL1) are specific for ligation post-U-deletion and are paralogous to KREL2 and KREPA1 that are specific for ligation post-U-insertion. KREPA2, is critical for RECC stability and KREL1 integration into the complex.


Pssm-ID: 467780 [Multi-domain]  Cd Length: 424  Bit Score: 42.16  E-value: 2.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  288 QAQAAHSSTEAQSAADRQSipdpAPSQDPPDP-APSqdPPDRAPSQDPQDSAPSQDPPdPALSQDPPDPVPSQDPPADNP 366
Cdd:cd23959    158 QHPPPAKPLPAAAAAQQSS----ASPGEVASPfASG--TVSASPFATATDTAPSSGAP-DGFPAEASAPSPFAAPASAAS 230

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 1348555408  367 geeqtsyYYRMKAAKKLKPPSSLLCVDCGSSFGMVSELVTHRKAQHGLK 415
Cdd:cd23959    231 -------FPAAPVANGEAATPTHACTICGKAFSTHEGLRMHSKAKHGVE 272
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 1041-1063 4.74e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 35.74  E-value: 4.74e-03
                           10        20
                   ....*....|....*....|...
gi 1348555408 1041 YTCHHCPSAFRSRSNLDKHIRLH 1063
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
COG5373 COG5373
Uncharacterized membrane protein [Function unknown];
298-369 8.21e-03

Uncharacterized membrane protein [Function unknown];


Pssm-ID: 444140 [Multi-domain]  Cd Length: 854  Bit Score: 40.37  E-value: 8.21e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1348555408  298 AQSAADRQSIPDPAPSQDPPDPAPSQDPPDRAPSQDPQDSAPSQDPPDPALSQDPPDPVPSQDPPADNPGEE 369
Cdd:COG5373     38 AEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEPAAAPAAASSFEE 109
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
672-863 8.29e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 53.16  E-value: 8.29e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  672 AKLMQDWSRTPLPHVCPHCGQTFTRRGFLRAHVFSHTGEKL-FTCKVCQKSFASSPNLLRH----SLTHMGTKPFPC--S 744
Cdd:COG5048    248 LSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLpIKSKQCNISFSRSSPLTRHlrsvNHSGESLKPFSCpyS 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  745 VCGKRFSQPGVLKRHGLTHSQPKSRRRRSRWKKRTPEGEDGE--------------SQLFAC--PNCTARFQTDQQLQEH 808
Cdd:COG5048    328 LCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqqykdlknDKKSETlsNSCIRNFKRDSNLSLH 407

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1348555408  809 RLLH---TSHPFPCSVCGEAFKRRKELDLHSLIHQDKEPVLCphCSSQFLNQSVLDIH 863
Cdd:COG5048    408 IITHlsfRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLC--SILKSFRRDLDLSN 463
PHA03247 PHA03247
large tegument protein UL36; Provisional
 298-366 9.15e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 50.32  E-value: 9.15e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1348555408  298 AQSAADRQSIPDPAPSQDPPDPA----------PSQDPPDRAPSqDPQDSAPSQDPPDPAlsqdPPDPVPSqDPPADNP 366
Cdd:PHA03247  2559 APPAAPDRSVPPPRPAPRPSEPAvtsrarrpdaPPQSARPRAPV-DDRGDPRGPAPPSPL----PPDTHAP-DPPPPSP 2631
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
718-1015 9.51e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 49.69  E-value: 9.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  718 CQKSFASSPNLLRHSLTHMGTKPFPCSV--CGKRFSQPGVLKRHGLTHSQpkSRRRRSRWKKRTPEGEDGESQLFACPNC 795
Cdd:COG5048     39 CTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHN--NPSDLNSKSLPLSNSKASSSSLSSSSSN 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  796 TARFQ-TDQQLQEHRLLHTSHPFPCSVC-----------GEAFKRRKELDLHSLIHQDKEPVLCPHCSSQFLNQSVLDIH 863
Cdd:COG5048    117 SNDNNlLSSHSLPPSSRDPQLPDLLSISnlrnnplpgnnSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLISSNVSTSI 196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  864 LQRCTSSVEDKTVGRGRGQGRGRSMGQVECDMCGHC-CMTQEGLDLHRLSHTGQTPLRCPLSPCRRRFASSSALGEHIVA 942
Cdd:COG5048    197 PSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNsQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPN 276

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1348555408  943 HcQGTLGKGRGSKRFHCQICGKDFAYTSTFNVHMR--IHTDE--RPFEC--STCGKRFRQLPHLKDHERIHSGLRPFCC 1015
Cdd:COG5048    277 E-SDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSISPAKE 354
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 279-372 6.08e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 47.29  E-value: 6.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  279 SNGSKASEIQAQAAHSSTEAQSAADRQSIPDPAPSQDPPDPAPSQDPPDRAPSQDPQDSAPSQDPPDPalsqDPPDPVPS 358
Cdd:PRK07764   712 GQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPP----SEEEEMAE 787

                           90
                   ....*....|....
gi 1348555408  359 QDPPADNPGEEQTS 372
Cdd:PRK07764   788 DDAPSMDDEDRRDA 801
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 286-371 6.68e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 47.29  E-value: 6.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  286 EIQAQAAHSSTEAQSAADRQSIPDPAPSQDPPDPAP-SQDPPDRAPSQDPQDSAPSQDPPDPALSQDPPDPVPSQDPPAD 364
Cdd:PRK07764   382 ERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPaAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAA 461


                   ....*..
gi 1348555408  365 NPGEEQT 371
Cdd:PRK07764   462 PSAQPAP 468
PHA03247 PHA03247
large tegument protein UL36; Provisional
 304-370 7.39e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.24  E-value: 7.39e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1348555408  304 RQSIPDPAPSQDPP-----DPAPSQDPPDRAPSQDPQDSAPSQDPPDPALSQDPPDPVPSQDPPADNPGEEQ 370
Cdd:PHA03247  2869 RSPAAKPAAPARPPvrrlaRPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQ 2940
zf-H2C2_2 pfam13465
Zinc-finger double domain;
727-752 7.96e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.82  E-value: 7.96e-05
                           10        20
                   ....*....|....*....|....*.
gi 1348555408  727 NLLRHSLTHMGTKPFPCSVCGKRFSQ 752
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
FAP pfam07174
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment ...
 291-367 1.07e-04

Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment proteins (FAP). Family members are rich in alanine and proline, are approximately 300 long, and seem to be restricted to mycobacteria. These proteins contain a fibronectin-binding motif that allows mycobacteria to bind to fibronectin in the extracellular matrix.


Pssm-ID: 429334  Cd Length: 301  Bit Score: 45.69  E-value: 1.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  291 AAHSSTEAQSAADRQSIPDPAPSQDPPDPAPSQDPPdraPSQDPQDSAPSQDPPDPALSQDPP-DP----VPSQDPPADN 365
Cdd:pfam07174   36 VAHADPEPAPPPPSTATAPPAPPPPPPAPAAPAPPP---PPAAPNAPNAPPPPADPNAPPPPPaDPnappPPAVDPNAPE 112


                   ..
gi 1348555408  366 PG 367
Cdd:pfam07174  113 PG 114
PHA03247 PHA03247
large tegument protein UL36; Provisional
 288-372 1.60e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.08  E-value: 1.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  288 QAQAAHSSTEAQSAADRQSIPDPAPSQD----PPDPAPSQDPPDRAPSQDPQDSAPSQDPPDPALSQdPPDPVPSQDPPA 363
Cdd:PHA03247  2869 RSPAAKPAAPARPPVRRLARPAVSRSTEsfalPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP-PPRPQPPLAPTT 2947


                   ....*....
gi 1348555408  364 DNPGEEQTS 372
Cdd:PHA03247  2948 DPAGAGEPS 2956
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 283-375 2.10e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 45.39  E-value: 2.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  283 KASEIQAQAAHSSTEAQSAADRqsiPDPAPSQDPPDPAPSQDPPDRAPS-------QDPQDSAP-SQDPPDPALSQDPPD 354
Cdd:NF033838   398 AEEEAKRKAAEEDKVKEKPAEQ---PQPAPAPQPEKPAPKPEKPAEQPKaekpadqQAEEDYARrSEEEYNRLTQQQPPK 474

                           90       100
                   ....*....|....*....|....
gi 1348555408  355 PVPSQDPPADNPGEEQTS---YYY 375
Cdd:NF033838   475 TEKPAQPSTPKTGWKQENgmwYFY 498
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 282-369 2.75e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 45.09  E-value: 2.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  282 SKASEIQAQAAHSSTEAQSAADRQSIPDPAPSQDPPDPAPSQDPPDRAP-----SQDPQDSAPSQDP-----------PD 345
Cdd:PRK14951   390 AAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPaaapaAVALAPAPPAQAApetvaipvrvaPE 469

                           90       100
                   ....*....|....*....|....
gi 1348555408  346 PALSQDPPDPVPSQDPPADNPGEE 369
Cdd:PRK14951   470 PAVASAAPAPAAAPAAARLTPTEE 493
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
 243-371 2.94e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 45.08  E-value: 2.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  243 SAEDTSANLDHMYLPNTTNRGQEGGEEEPETESVGESNGSKASEIQAQAAHSSTEAQSA--ADRQSIPDPAPSQDPPDPA 320
Cdd:PRK08691   364 ASCDANAVIENTELQSPSAQTAEKETAAKKPQPRPEAETAQTPVQTASAAAMPSEGKTAgpVSNQENNDVPPWEDAPDEA 443

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1348555408  321 PSQDPPDRAPSQDPQDSAPSQDPPDPALSQDP-------------PDPVPSQDPPADNPGEEQT 371
Cdd:PRK08691   444 QTAAGTAQTSAKSIQTASEAETPPENQVSKNKaadnetdaplsevPSENPIQATPNDEAVETET 507
zf-H2C2_2 pfam13465
Zinc-finger double domain;
975-996 3.11e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 3.11e-04
                           10        20
                   ....*....|....*....|..
gi 1348555408  975 HMRIHTDERPFECSTCGKRFRQ 996
Cdd:pfam13465    5 HMRTHTGEKPYKCPECGKSFKS 26
PHA03247 PHA03247
large tegument protein UL36; Provisional
 287-388 4.71e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 4.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  287 IQAQAAHSSTEAQSAADRQSIPDPAPSQDPPDPAPSqdPPDRAPSqDPQDSAPSQDPPDPALSQDPPDPVPSQDPPADNP 366
Cdd:PHA03247  2582 VTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPL--PPDTHAP-DPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAP 2658

                           90       100
                   ....*....|....*....|..
gi 1348555408  367 GeeQTSYYYRMKAAKKLKPPSS 388
Cdd:PHA03247  2659 G--RVSRPRRARRLGRAAQASS 2678
PHA03369 PHA03369
capsid maturational protease; Provisional
 280-385 5.44e-04

capsid maturational protease; Provisional


Pssm-ID: 223061 [Multi-domain]  Cd Length: 663  Bit Score: 44.22  E-value: 5.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  280 NGSKASEIQAQAAHSSTEAQSAADRQSIPDPAPSQDPPDPAPSQDP--PDRAPSQDPQDSAPSQDP--------PDPALS 349
Cdd:PHA03369   339 NGLKAHNEILKTASLTAPSRVLAAAAKVAVIAAPQTHTGPADRQRPqrPDGIPYSVPARSPMTAYPpvpqfcgdPGLVSP 418

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1348555408  350 QDPPDPVPSQDPPADNPGEEQ--TSYYYRMKAAKKLKP 385
Cdd:PHA03369   419 YNPQSPGTSYGPEPVGPVPPQptNPYVMPISMANMVYP 456
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 275-372 6.24e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.01  E-value: 6.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  275 SVGESNGSKASEIQAQAAHSSTEAQSAADRQSIPDPAPSQDPPDPAPSQDPPDRAPSQDPQDSAPSQDPPDP-------- 346
Cdd:PHA03307   314 ASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPtrrraraa 393

                           90       100       110
                   ....*....|....*....|....*....|
gi 1348555408  347 ----ALSQDPPDPVPSQDPPADNPGEEQTS 372
Cdd:PHA03307   394 vagrARRRDATGRFPAGRPRPSPLDAGAAS 423
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 289-373 6.40e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 44.03  E-value: 6.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  289 AQAAHSSTEAQSAADrqsiPDPAPSQdPPDPAPSQDPPDRAPSQDPQDsaPSQDPPDPALSQ-DPPDPVPSQDPPADNPG 367
Cdd:PRK14950   366 PQPAKPTAAAPSPVR----PTPAPST-RPKAAAAANIPPKEPVRETAT--PPPVPPRPVAPPvPHTPESAPKLTRAAIPV 438


                   ....*.
gi 1348555408  368 EEQTSY 373
Cdd:PRK14950   439 DEKPKY 444
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 289-371 6.47e-04

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 44.11  E-value: 6.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  289 AQAAHSSTEAQSAADRQSIPDPAPSQDPPDPAPSQDPPDRAPSQDPqdsAPSQDPPDPALSQDPPDPVPSQDPPADNPGE 368
Cdd:PRK12270    39 GSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPP---KPAAAAAAAAAPAAPPAAAAAAAPAAAAVED 115


                   ...
gi 1348555408  369 EQT 371
Cdd:PRK12270   116 EVT 118
PRK12495 PRK12495
hypothetical protein; Provisional
 282-363 6.96e-04

hypothetical protein; Provisional


Pssm-ID: 183558 [Multi-domain]  Cd Length: 226  Bit Score: 42.55  E-value: 6.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  282 SKASEIQAQAAHSSTEAQSAADRQSIPDPAPSQDPPDPAPSQDPPDRAPSQDPQDSAPSQDPPDPALSQDPPDPVPSQDP 361
Cdd:PRK12495    88 SDAGSQASPDDDAQPAAEAEAADQSAPPEASSTSATDEAATDPPATAAARDGPTPDPTAQPATPDERRSPRQRPPVSGEP 167


                   ..
gi 1348555408  362 PA 363
Cdd:PRK12495   168 PT 169
zf-H2C2_2 pfam13465
Zinc-finger double domain;
999-1023 7.38e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 7.38e-04
                           10        20
                   ....*....|....*....|....*
gi 1348555408  999 HLKDHERIHSGLRPFCCWVCGKAFS 1023
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFK 25
PHA03247 PHA03247
large tegument protein UL36; Provisional
 283-368 8.57e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.77  E-value: 8.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  283 KASEIQAQAAHSSTEAQS----AADRQSIPDPAPSQDPPDPAPSQDPPDRAPSQDPQDSAPSQDPPDPALSQDPPDPVPS 358
Cdd:PHA03247  2882 PVRRLARPAVSRSTESFAlppdQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQ 2961

                           90
                   ....*....|
gi 1348555408  359 QDPPADNPGE 368
Cdd:PHA03247  2962 PWLGALVPGR 2971
PHA01929 PHA01929
putative scaffolding protein
 280-369 8.60e-04

putative scaffolding protein


Pssm-ID: 177328  Cd Length: 306  Bit Score: 42.73  E-value: 8.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  280 NGSKASEIQAQAAHSSTEAQSAADRQsIPDPAPSQDPPDPAPSQDPPdrapsQDPQDSAPSQDPPDPALSQDPPDPVPsq 359
Cdd:PHA01929    26 TPQPNPVIQPQAPVQPGQPGAPQQLA-IPTQQPQPVPTSAMTPHVVQ-----QAPAQPAPAAPPAAGAALPEALEVPP-- 97

                           90
                   ....*....|
gi 1348555408  360 dPPADNPGEE 369
Cdd:PHA01929    98 -PPAFTPNGE 106
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 284-363 1.00e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.44  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  284 ASEIQAQAAHSSTEAQSAADRQSiPDPAPSQDPPDPAPSQDPPDRAPSQDPQDSAPSQDPPDPALSQDPPDPVPSQDPPA 363
Cdd:PRK07764   414 AAAPAAAAAPAPAAAPQPAPAPA-PAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAA 492
PHA03247 PHA03247
large tegument protein UL36; Provisional
 295-362 1.33e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 1.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  295 STEAQSAADRQSIPDPAPSQDPPDPAPSQDPPDR---APSQDPQDSAPSQDPPDPAL---------SQDPPDPVPSQDPP 362
Cdd:PHA03247  2632 SPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRrarRLGRAAQASSPPQRPRRRAArptvgsltsLADPPPPPPTPEPA 2711
PRK10856 PRK10856
cytoskeleton protein RodZ;
286-372 1.53e-03

cytoskeleton protein RodZ;


Pssm-ID: 236776 [Multi-domain]  Cd Length: 331  Bit Score: 42.32  E-value: 1.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  286 EIQAQAAHSSTEaQSAADRQSIP-------DPAPSQDPPDPAPSQDPPDR--------APSQDPQDSA---PSQDPPDPA 347
Cdd:PRK10856   142 EITTMADQSSAE-LSQNSGQSVPldtstttDPATTPAPAAPVDTTPTNSQtpavatapAPAVDPQQNAvvaPSQANVDTA 220

                           90       100
                   ....*....|....*....|....*
gi 1348555408  348 LSQDPPDPVPSQDPPADNPGEEQTS 372
Cdd:PRK10856   221 ATPAPAAPATPDGAAPLPTDQAGVS 245
dnaA PRK14086
chromosomal replication initiator protein DnaA;
292-373 1.55e-03

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 42.51  E-value: 1.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  292 AHSSTEAQSAADRQS-IPDPAPS----QDPPDPAPSQDPPDRAPSQDPQDSAPSQDPPDPAlSQDPPDPVPSQDPPADNP 366
Cdd:PRK14086   123 GPRADDRPPGLPRQDqLPTARPAypayQQRPEPGAWPRAADDYGWQQQRLGFPPRAPYASP-ASYAPEQERDREPYDAGR 201


                   ....*..
gi 1348555408  367 GEEQTSY 373
Cdd:PRK14086   202 PEYDQRR 208
DUF3664 pfam12406
Surface protein; This family of proteins is found in eukaryotes. Proteins in this family are ...
 303-370 1.66e-03

Surface protein; This family of proteins is found in eukaryotes. Proteins in this family are typically between 131 and 312 amino acids in length.


Pssm-ID: 289191 [Multi-domain]  Cd Length: 99  Bit Score: 39.09  E-value: 1.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  303 DRQSIP---DPAPSQDPPDP-------APSQDPPDRAPSQDPQDSAPSQDPPD---PALSQDPPDPVPSQDPPADNPGEE 369
Cdd:pfam12406    1 DRQLNPidfDPNDDQHPLDPdqlidqiEPSEQPAQQEPIEPQQPTQPSTEPEElqpETVTVEVPEPVTSEEPKESDQTEE 80


                   .
gi 1348555408  370 Q 370
Cdd:pfam12406   81 Q 81
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 284-364 1.85e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.67  E-value: 1.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  284 ASEIQAQAAHSSTEAQSAADRQSIPDPAPSQDPPDPAPSQDPPDRAPSQDPQDSAPSQD--PPDPALSQDPPDPVPSQDP 361
Cdd:PRK07764   427 AAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPaaPAPAAAPAAPAAPAAPAGA 506


                   ...
gi 1348555408  362 PAD 364
Cdd:PRK07764   507 DDA 509
motB PRK05996
MotB family protein;
289-365 1.99e-03

MotB family protein;


Pssm-ID: 235665 [Multi-domain]  Cd Length: 423  Bit Score: 41.99  E-value: 1.99e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1348555408  289 AQAAHSSTEAQSAADrqSIPDPAPSQDPPDPAPSQDPPDRAPSQDPQDSAPSQDPPDPAlSQDPPDPVPSQDPPADN 365
Cdd:PRK05996   202 GQAREQAQGAKSATA--APATVPQAAPLPQAQPKKAATEEELIADAKKAATGEPAANAA-KAAKPEPMPDDQQKEAE 275
KREPA2 cd23959
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of ...
 288-415 2.04e-03

Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of the parasitic protozoan's KREPA RNA editing catalytic complex (RECC). Kinetoplastid RNA editing (KRE) proteins occur as pairs or sets of related proteins in multiple complexes. KREPA complex is composed of six components (KREPA1-6), which share a conserved C-terminal region containing an oligonucleotide-binding (OB)-fold-like domain. KREPAs are responsible for the site-specific insertion and deletion of U nucleotides in the kinetoplastid mitochondria pre-messenger RNA. Apart from the conserved C-terminal OB-fold domain, KREPA1, KREPA2, and KREPA3 contain two conserved C2H2 zinc-finger domains. KREPA2 and kinetoplastid RNA editing ligase 1 (KREL1) are specific for ligation post-U-deletion and are paralogous to KREL2 and KREPA1 that are specific for ligation post-U-insertion. KREPA2, is critical for RECC stability and KREL1 integration into the complex.


Pssm-ID: 467780 [Multi-domain]  Cd Length: 424  Bit Score: 42.16  E-value: 2.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  288 QAQAAHSSTEAQSAADRQSipdpAPSQDPPDP-APSqdPPDRAPSQDPQDSAPSQDPPdPALSQDPPDPVPSQDPPADNP 366
Cdd:cd23959    158 QHPPPAKPLPAAAAAQQSS----ASPGEVASPfASG--TVSASPFATATDTAPSSGAP-DGFPAEASAPSPFAAPASAAS 230

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 1348555408  367 geeqtsyYYRMKAAKKLKPPSSLLCVDCGSSFGMVSELVTHRKAQHGLK 415
Cdd:cd23959    231 -------FPAAPVANGEAATPTHACTICGKAFSTHEGLRMHSKAKHGVE 272
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 308-363 2.08e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 42.10  E-value: 2.08e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1348555408  308 PDPAPSQDPP-DPAPSQDPPDRAPSQDPQDSAPSQDPPDPALSQDPPDPVPSQDPPA 363
Cdd:PRK14950   362 PVPAPQPAKPtAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVA 418
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 289-363 2.20e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.47  E-value: 2.20e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1348555408  289 AQAAHSSTEAQSAADRQSIPDPAPSQDPPDPAPSqDPPDRAPSQDPQDSAPSQDPPDPALSQDPPDPVPSQDPPA 363
Cdd:PHA03307    96 APASPAREGSPTPPGPSSPDPPPPTPPPASPPPS-PAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASS 169
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
289-369 2.35e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 41.87  E-value: 2.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  289 AQAAHSSTEAQSAADRQSIPDPAPSQDPPDPAPSQDPPDRAPSQDPQDSAPSQDPPDPALSQDPPDPVPSQDPPADNPGE 368
Cdd:PRK14948   516 SASNTAKTPPPPQKSPPPPAPTPPLPQPTATAPPPTPPPPPPTATQASSNAPAQIPADSSPPPPIPEEPTPSPTKDSSPE 595


                   .
gi 1348555408  369 E 369
Cdd:PRK14948   596 E 596
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
284-368 3.02e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 41.76  E-value: 3.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  284 ASEIQAQAAHSSTEAQSAADRQS-IPDPAPSQDPPDPAPSQDPPDRAPSQDPQDSAPSQDPPDPALSQDPP-DPVPSQDP 361
Cdd:PRK07003   425 APPAAPAPPATADRGDDAADGDApVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRaAAPSAATP 504


                   ....*..
gi 1348555408  362 PADNPGE 368
Cdd:PRK07003   505 AAVPDAR 511
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
276-363 3.29e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 41.76  E-value: 3.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  276 VGESNGSKASEIQAQAAHSSTEAQSAADR---QSIPDPAPSQDPPDPAPSQDPPDRAPSQDPQDSAPSQDPPDPALSQDP 352
Cdd:PRK07003   428 AAPAPPATADRGDDAADGDAPVPAKANARasaDSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAV 507

                           90
                   ....*....|.
gi 1348555408  353 PDPVPSQDPPA 363
Cdd:PRK07003   508 PDARAPAAASR 518
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
284-366 3.58e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 41.76  E-value: 3.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  284 ASEIQAQAAHSSTE--AQSAADRQSIPDPAPSQDPPDPAPSQDPPDRAPSQDPQDSAPSQDPPDPALSQDPPDPVPSQDP 361
Cdd:PRK07003   428 AAPAPPATADRGDDaaDGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAV 507


                   ....*
gi 1348555408  362 PADNP 366
Cdd:PRK07003   508 PDARA 512
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
288-371 4.59e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 41.30  E-value: 4.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  288 QAQAAHSSTEAQSA-ADRQSIPDPAPSQDPPDPAPSQDPPDRAPSQdPQDSAPSQDPPDPALSQDPPDP--VPSQDPPAD 364
Cdd:PRK14971   393 SAAAAASPSPSQSSaAAQPSAPQSATQPAGTPPTVSVDPPAAVPVN-PPSTAPQAVRPAQFKEEKKIPVskVSSLGPSTL 471


                   ....*..
gi 1348555408  365 NPGEEQT 371
Cdd:PRK14971   472 RPIQEKA 478
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 1041-1063 4.74e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 35.74  E-value: 4.74e-03
                           10        20
                   ....*....|....*....|...
gi 1348555408 1041 YTCHHCPSAFRSRSNLDKHIRLH 1063
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 289-372 5.43e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 5.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  289 AQAAHSSTEAQSAAdrQSIPDPAPSQDPPDPAPSQDPPDRAPSQDPQDSAPSQDPPDPALSQDPPDPVPSQDPPADNPGE 368
Cdd:PRK07764   416 APAAAAAPAPAAAP--QPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAA 493


                   ....
gi 1348555408  369 EQTS 372
Cdd:PRK07764   494 PAAP 497
PHA03247 PHA03247
large tegument protein UL36; Provisional
 310-370 5.47e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 5.47e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1348555408  310 PAPSQDPPDPAPSQDPPDRAPSQdPQDSAPSQDPPDPALSQDPPDPVPSQDPPADNPGEEQ 370
Cdd:PHA03247  2866 PPSRSPAAKPAAPARPPVRRLAR-PAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPP 2925
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 985-1007 7.23e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 34.97  E-value: 7.23e-03
                           10        20
                   ....*....|....*....|...
gi 1348555408  985 FECSTCGKRFRQLPHLKDHERIH 1007
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
NESP55 pfam06390
Neuroendocrine-specific golgi protein P55 (NESP55); This family consists of several mammalian ...
 293-366 7.57e-03

Neuroendocrine-specific golgi protein P55 (NESP55); This family consists of several mammalian neuroendocrine-specific golgi protein P55 (NESP55) sequences. NESP55 is a novel member of the chromogranin family and is a soluble, acidic, heat-stable secretory protein that is expressed exclusively in endocrine and nervous tissues, although less widely than chromogranins.


Pssm-ID: 115071 [Multi-domain]  Cd Length: 261  Bit Score: 39.85  E-value: 7.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  293 HSSTEAQSAADRQSiPDPAPSQDPPDpapSQDPPDRAPSQDPQDSAPSQDPPDPALSQDPPD-------------PVPSQ 359
Cdd:pfam06390  168 QSLTERLHALKLQS-ADASPRRAPPS---TQEPESAREGEEPERGPLDKDPRDPEEEEEEKEeekqqphrckpkkPARRR 243


                   ....*..
gi 1348555408  360 DPPADNP 366
Cdd:pfam06390  244 DPSPESP 250
COG5373 COG5373
Uncharacterized membrane protein [Function unknown];
298-369 8.21e-03

Uncharacterized membrane protein [Function unknown];


Pssm-ID: 444140 [Multi-domain]  Cd Length: 854  Bit Score: 40.37  E-value: 8.21e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1348555408  298 AQSAADRQSIPDPAPSQDPPDPAPSQDPPDRAPSQDPQDSAPSQDPPDPALSQDPPDPVPSQDPPADNPGEE 369
Cdd:COG5373     38 AEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEPAAAPAAASSFEE 109
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 277-358 9.01e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.54  E-value: 9.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  277 GESNGSKASEIQAQAAHSSTEAQSAADRQSiPDPAPSQDPPDPAPSQDPPDRAPSQDPQDSAPSQDPPDPALSQDPPDPV 356
Cdd:PHA03307   143 SPGPPPAASPPAAGASPAAVASDAASSRQA-ALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPA 221


                   ..
gi 1348555408  357 PS 358
Cdd:PHA03307   222 PA 223
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
275-362 9.42e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.22  E-value: 9.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  275 SVGESNGSKASEIQAQAAHSSTEAQSAADRQSIPDPAPSQDPPDPAPSQDPPdRAPSQDPQDSAPSQDPPDPALSQDPPD 354
Cdd:PRK07003   443 ADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAP-RAAAPSAATPAAVPDARAPAAASREDA 521


                   ....*...
gi 1348555408  355 PVPSQDPP 362
Cdd:PRK07003   522 PAAAAPPA 529
PHA03169 PHA03169
hypothetical protein; Provisional
 277-370 9.44e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 39.95  E-value: 9.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1348555408  277 GESNGSKASEIQAQAAHSSTEAQSAADRQSIPDPAPSQDPPDPAPSQDPPDRAPSQDPQDSAPSQDPPDPALSQDPPD-P 355
Cdd:PHA03169   111 AEELASGLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAPPESHNPSPNQQPSSFLQPSHEDSPEEPEPPTSEPEPDsP 190

                           90       100
                   ....*....|....*....|....*
gi 1348555408  356 VPSQDP----------PADNPGEEQ 370
Cdd:PHA03169   191 GPPQSEtptsspppqsPPDEPGEPQ 215
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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