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Conserved domains on  [gi|1246192453|ref|XP_022442274|]
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enoyl-CoA delta isomerase 2, mitochondrial isoform X3 [Delphinapterus leucas]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 10468274)

enoyl-CoA hydratase/isomerase family protein similar to enoyl-CoA hydratase, which catalyzes the second step in the beta-oxidation pathway of fatty acid metabolism, the syn-addition of a water molecule across the double bond of a trans-2-enoyl-CoA thioester, resulting in the formation of a beta-hydroxyacyl-CoA thioester

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
92-342 3.05e-62

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


:

Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 198.85  E-value: 3.05e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  92 LVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDS--AItVLTGNGDYYCSGNDLTNFTDIPPggvEEKARS 169
Cdd:COG1024     1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDvrVV-VLTGAGKAFCAGADLKELAAAAD---PEEARA 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 170 GAVLLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEM 249
Cdd:COG1024    77 FARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKEL 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 250 LVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVIRNTEKEKLHAINAEESNILRERWLSDE 329
Cdd:COG1024   157 LLTGRRIDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASED 236
                         250
                  ....*....|...
gi 1246192453 330 CMNAVVSFLSKKA 342
Cdd:COG1024   237 AREGIAAFLEKRK 249
ACBP pfam00887
Acyl CoA binding protein;
20-65 1.33e-20

Acyl CoA binding protein;


:

Pssm-ID: 459982  Cd Length: 76  Bit Score: 84.19  E-value: 1.33e-20
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1246192453  20 KQATEGPCNVPKPGVLDFINKAKWDAWNALGSLPKETARHNYVDLV 65
Cdd:pfam00887  31 KQATVGDCNTPRPGMFDFKGKAKWDAWKKLGGMSKEEAMAKYVELV 76
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
92-342 3.05e-62

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 198.85  E-value: 3.05e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  92 LVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDS--AItVLTGNGDYYCSGNDLTNFTDIPPggvEEKARS 169
Cdd:COG1024     1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDvrVV-VLTGAGKAFCAGADLKELAAAAD---PEEARA 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 170 GAVLLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEM 249
Cdd:COG1024    77 FARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKEL 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 250 LVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVIRNTEKEKLHAINAEESNILRERWLSDE 329
Cdd:COG1024   157 LLTGRRIDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASED 236
                         250
                  ....*....|...
gi 1246192453 330 CMNAVVSFLSKKA 342
Cdd:COG1024   237 AREGIAAFLEKRK 249
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
92-281 9.80e-62

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 195.47  E-value: 9.80e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  92 LVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLTNFTDIPPGGveEKARSG 170
Cdd:cd06558     1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVrVVVLTGAGKAFCAGADLKELAALSDAG--EEARAF 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 171 AVLLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEML 250
Cdd:cd06558    79 IRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELL 158
                         170       180       190
                  ....*....|....*....|....*....|.
gi 1246192453 251 VFGKKLTAREACTQGLVTEVFPDSTFQKEVW 281
Cdd:cd06558   159 LTGRRISAEEALELGLVDEVVPDEELLAAAL 189
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
87-342 1.70e-58

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 189.69  E-value: 1.70e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  87 PGSDALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSAITV-LTGNGDYYCSGNDLTNFTDIPPGGVEE 165
Cdd:PRK06688    2 TMVTDLLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVvLTGAGRAFSAGGDIKDFPKAPPKPPDE 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 166 KARsgavlLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSK 245
Cdd:PRK06688   82 LAP-----VNRFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRAR 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 246 ATEMLVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVIRNTEKEKLHAINAEESNILRERW 325
Cdd:PRK06688  157 AAEMLLLGEPLSAEEALRIGLVNRVVPAAELDAEADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLL 236
                         250
                  ....*....|....*..
gi 1246192453 326 LSDECMNAVVSFLSKKA 342
Cdd:PRK06688  237 RTPDFREGATAFIEKRK 253
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
97-299 1.84e-31

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 118.62  E-value: 1.84e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  97 QDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLTnftDIPPGGVEEKARSGAVLLr 175
Cdd:pfam00378   3 NAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVrAVVLTGGDKAFCAGADLK---EMYGEGPAHQALYRENVL- 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 176 DFVDRFIDFPKPLVAVVNGPAVGiSVTILGLF-DIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEMLVFGK 254
Cdd:pfam00378  79 DLWTLLYTCPKPVIAAVNGYAIG-GGCELALAcDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGR 157
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1246192453 255 KLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISK 299
Cdd:pfam00378 158 RISAQEALKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALAQLK 202
ACBP pfam00887
Acyl CoA binding protein;
20-65 1.33e-20

Acyl CoA binding protein;


Pssm-ID: 459982  Cd Length: 76  Bit Score: 84.19  E-value: 1.33e-20
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1246192453  20 KQATEGPCNVPKPGVLDFINKAKWDAWNALGSLPKETARHNYVDLV 65
Cdd:pfam00887  31 KQATVGDCNTPRPGMFDFKGKAKWDAWKKLGGMSKEEAMAKYVELV 76
ACBP cd00435
Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a ...
9-65 6.53e-20

Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a role in regulation of intermediary metabolism and gene regulation. The suggested role of ACBP is to act as a intracellular acyl-CoA transporter and pool former. ACBPs are present in a large group of eukaryotic species and several tissue-specific isoforms have been detected.


Pssm-ID: 238248  Cd Length: 85  Bit Score: 82.76  E-value: 6.53e-20
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1246192453   9 NEAKKERKGWMKQATEGPCNVPKPGVLDFINKAKWDAWNALGSLPKETARHNYVDLV 65
Cdd:cd00435    21 NEEKLQLYSLYKQATVGDCNTERPGMFDLKGRAKWDAWNSLKGMSKEDAMKAYIAKV 77
ACB COG4281
Acyl-CoA-binding protein [Lipid transport and metabolism];
20-65 2.09e-13

Acyl-CoA-binding protein [Lipid transport and metabolism];


Pssm-ID: 443422  Cd Length: 87  Bit Score: 64.87  E-value: 2.09e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1246192453  20 KQATEGPCNVPKPGVLDFINKAKWDAWNALGSLPKETARHNYVDLV 65
Cdd:COG4281    35 KQATEGDVTGKRPGMTDFVGRAKYDAWAQLKGMSKDEAMQQYIDLV 80
PTZ00458 PTZ00458
acyl CoA binding protein; Provisional
9-65 9.52e-07

acyl CoA binding protein; Provisional


Pssm-ID: 185637  Cd Length: 90  Bit Score: 46.35  E-value: 9.52e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1246192453   9 NEAKKERKGWMKQATEGPCNVPKPGVLDFINKAKWDAWNALGSLPKETARHNYVDLV 65
Cdd:PTZ00458   23 VEIKLDLYKYYKQSTVGNCNIKEPSMFKYQDRKKYEAWKSIENLNREDAKKRYVEIV 79
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
84-270 2.14e-04

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 43.29  E-value: 2.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  84 RKQPGSDALVVTS------QDGITTITLNRPDKK-NALTTQMYHDIMLALEAASKDDS--AITVLTGNGDYYCSGNDLTN 154
Cdd:TIGR02441   1 RLFSTSAALMARThrhyevKGDVAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAikSAVLISGKPGSFVAGADIQM 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 155 ftdIPPGGVEEKARSGAVLLRDFVDRFIDFPKPLVAVVNGPAVG--ISVTILGLFDIVYATDRATFHTPFSHLGQSPEGC 232
Cdd:TIGR02441  81 ---IAACKTAQEVTQLSQEGQEMFERIEKSQKPIVAAISGSCLGggLELALACHYRIATKDRKTLLGLPEVMLGLLPGAG 157
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1246192453 233 SSYTFPKIMGPSKATEMLVFGKKLTAREACTQGLVTEV 270
Cdd:TIGR02441 158 GTQRLPKLTGVPAALDMMLTGKKIRADRAKKMGIVDQL 195
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
92-342 3.05e-62

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 198.85  E-value: 3.05e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  92 LVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDS--AItVLTGNGDYYCSGNDLTNFTDIPPggvEEKARS 169
Cdd:COG1024     1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDvrVV-VLTGAGKAFCAGADLKELAAAAD---PEEARA 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 170 GAVLLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEM 249
Cdd:COG1024    77 FARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKEL 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 250 LVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVIRNTEKEKLHAINAEESNILRERWLSDE 329
Cdd:COG1024   157 LLTGRRIDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASED 236
                         250
                  ....*....|...
gi 1246192453 330 CMNAVVSFLSKKA 342
Cdd:COG1024   237 AREGIAAFLEKRK 249
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
92-281 9.80e-62

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 195.47  E-value: 9.80e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  92 LVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLTNFTDIPPGGveEKARSG 170
Cdd:cd06558     1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVrVVVLTGAGKAFCAGADLKELAALSDAG--EEARAF 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 171 AVLLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEML 250
Cdd:cd06558    79 IRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELL 158
                         170       180       190
                  ....*....|....*....|....*....|.
gi 1246192453 251 VFGKKLTAREACTQGLVTEVFPDSTFQKEVW 281
Cdd:cd06558   159 LTGRRISAEEALELGLVDEVVPDEELLAAAL 189
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
87-342 1.70e-58

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 189.69  E-value: 1.70e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  87 PGSDALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSAITV-LTGNGDYYCSGNDLTNFTDIPPGGVEE 165
Cdd:PRK06688    2 TMVTDLLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVvLTGAGRAFSAGGDIKDFPKAPPKPPDE 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 166 KARsgavlLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSK 245
Cdd:PRK06688   82 LAP-----VNRFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRAR 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 246 ATEMLVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVIRNTEKEKLHAINAEESNILRERW 325
Cdd:PRK06688  157 AAEMLLLGEPLSAEEALRIGLVNRVVPAAELDAEADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLL 236
                         250
                  ....*....|....*..
gi 1246192453 326 LSDECMNAVVSFLSKKA 342
Cdd:PRK06688  237 RTPDFREGATAFIEKRK 253
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
99-340 1.64e-44

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 153.02  E-value: 1.64e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  99 GITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLTNFTDIPPGGveekaRSGAVLLRDF 177
Cdd:PRK06023   15 GVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIrAHVFLGTEGCFSAGNDMQDFLAAAMGG-----TSFGSEILDF 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 178 VDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEMLVFGKKLT 257
Cdd:PRK06023   90 LIALAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLALGEGFS 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 258 AREACTQGLVTEVFPDSTFQKEVwvrLKAYSKL---PPNAMRISKQVIRNTEKEKLHAInAEESNILRERWLSDECMNAV 334
Cdd:PRK06023  170 AEAAQEAGLIWKIVDEEAVEAET---LKAAEELaakPPQALQIARDLMRGPREDILARI-DEEAKHFAARLKSAEARAAF 245

                  ....*.
gi 1246192453 335 VSFLSK 340
Cdd:PRK06023  246 EAFMRR 251
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
97-272 8.84e-40

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 142.07  E-value: 8.84e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  97 QDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDS--AItVLTGNGDYYCSGNDLTnftdiPPGGV---EEKARSGA 171
Cdd:PRK08260   11 ADGIATITLNRPDKLNAFTVTMARELIEAFDAADADDAvrAV-IVTGAGRAFCAGADLS-----AGGNTfdlDAPRTPVE 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 172 VLLRDFVD---------------RFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYT 236
Cdd:PRK08260   85 ADEEDRADpsddgvrdgggrvtlRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWF 164
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1246192453 237 FPKIMGPSKATEMLVFGKKLTAREACTQGLVTEVFP 272
Cdd:PRK08260  165 LPRLVGLQTALEWVYSGRVFDAQEALDGGLVRSVHP 200
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
99-342 3.37e-35

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 129.44  E-value: 3.37e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  99 GITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLTNFTDIPPGGVeekarSGAVLLRDF 177
Cdd:PRK06210   15 GVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVrVIVLTGAGRGFCAGADMGELQTIDPSDG-----RRDTDVRPF 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 178 V-DRFIDF----------PKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKA 246
Cdd:PRK06210   90 VgNRRPDYqtryhfltalRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRLVGHANA 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 247 TEMLVFGKKLTAREACTQGLVTEVFPDStfqkEVWVRLKAYSK-----LPPNAMRISKQVIRNTEKEKLHAINAEESNIL 321
Cdd:PRK06210  170 LDLLLSARTFYAEEALRLGLVNRVVPPD----ELMERTLAYAEdlarnVSPASMAVIKRQLYEDAFQTLAEATARANREM 245
                         250       260
                  ....*....|....*....|.
gi 1246192453 322 RERWLSDECMNAVVSFLSKKA 342
Cdd:PRK06210  246 HESLQRPDFIEGVASFLEKRP 266
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
89-312 2.13e-32

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 121.37  E-value: 2.13e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  89 SDALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSAIT-VLTGNGDYYCSGNDLTNFTDIPPGGVEEKa 167
Cdd:PRK05870    2 MDPVLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHAlVVTGAGKAFCAGADLTALGAAPGRPAEDG- 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 168 rsgavlLRDFVDRFIDF---PKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPS 244
Cdd:PRK05870   81 ------LRRIYDGFLAVascPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGPQ 154
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1246192453 245 KATEMLVFGKKLTAREACTQGLVTEVFPDStfQKEVWVRLKAYSKLPPNAMRISKQVIRNTEKEKLHA 312
Cdd:PRK05870  155 VARAALLFGMRFDAEAAVRHGLALMVADDP--VAAALELAAGPAAAPRELVLATKASMRATASLAQHA 220
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
97-299 1.84e-31

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 118.62  E-value: 1.84e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  97 QDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLTnftDIPPGGVEEKARSGAVLLr 175
Cdd:pfam00378   3 NAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVrAVVLTGGDKAFCAGADLK---EMYGEGPAHQALYRENVL- 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 176 DFVDRFIDFPKPLVAVVNGPAVGiSVTILGLF-DIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEMLVFGK 254
Cdd:pfam00378  79 DLWTLLYTCPKPVIAAVNGYAIG-GGCELALAcDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGR 157
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1246192453 255 KLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISK 299
Cdd:pfam00378 158 RISAQEALKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALAQLK 202
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
93-342 1.57e-29

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 114.00  E-value: 1.57e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  93 VVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDL----TNFTDIPPGGVEEkA 167
Cdd:PRK07468    8 IAVDARGVATLTLNRPEKHNALSARMIAELTTAARRLAADAAVrVVVLTGAGKSFCAGGDLgwmrAQMTADRATRIEE-A 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 168 RSGAVLLRDFVDrfidFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKiMGPSKAT 247
Cdd:PRK07468   87 RRLAMMLKALND----LPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVAR-MGEANAR 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 248 EMLVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVIRNTEKEKLHAINAEESNILRERWLS 327
Cdd:PRK07468  162 RVFMSARLFDAEEAVRLGLLSRVVPAERLDAAVEAEVTPYLSCAPGAVAAAKALVRALGAPIDEAVIDATIEALADTWET 241
                         250
                  ....*....|....*
gi 1246192453 328 DECMNAVVSFLSKKA 342
Cdd:PRK07468  242 EEAREGIAAFFDKRA 256
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
97-342 6.26e-29

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 112.52  E-value: 6.26e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  97 QDGITTITLNRPDKKNALTTQMYHDIMLALEA--ASKDDSAITVLTGNGDYYCSGNDLTNFTDIP-PGGVEEKArsGAVL 173
Cdd:PRK05981   11 DGGVAILTLDHPEVMNAVSIDMLGGLAEALDAieDGKAEVRCLVLTGAGRGFCTGANLQGRGSGGrESDSGGDA--GAAL 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 174 L---RDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEML 250
Cdd:PRK05981   89 EtayHPFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGKARAMELS 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 251 VFGKKLTAREACTQGLVTEVFPDStfqkEVWVRLKAYSKLPPNAMRISKQVIR--------NTEKEKLHAinaeESNILR 322
Cdd:PRK05981  169 LLGEKLPAETALQWGLVNRVVDDA----ELMAEAMKLAHELANGPTVALGLIRklywdspeNDFEEQLNL----EREAQR 240
                         250       260
                  ....*....|....*....|
gi 1246192453 323 ERWLSDECMNAVVSFLSKKA 342
Cdd:PRK05981  241 IAGKTEDFKEGVGAFLQKRP 260
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
89-280 8.01e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 109.23  E-value: 8.01e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  89 SDALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSAITVLTGNGDYYCSGNDLTNfTDIPPGGveEKAR 168
Cdd:PRK08140    3 YETILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVEDDGARALLLTGAGRGFCAGQDLAD-RDVTPGG--AMPD 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 169 SGAVLLRDF---VDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSK 245
Cdd:PRK08140   80 LGESIETFYnplVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMAR 159
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1246192453 246 ATEMLVFGKKLTAREACTQGLVTEVFPDSTFQKEV 280
Cdd:PRK08140  160 ALGLALLGEKLSAEQAEQWGLIWRVVDDAALADEA 194
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
90-342 3.29e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 107.70  E-value: 3.29e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  90 DALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDS--AItVLTGNGDYYCSGNDLtNFTDIPPGGVEEKA 167
Cdd:PRK05995    4 ETLEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSvrAV-VLAGAGKAFCAGADL-NWMKKMAGYSDDEN 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 168 RSGAVLLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFpKIMGPSKAT 247
Cdd:PRK05995   82 RADARRLADMLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPYVI-RAMGERAAR 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 248 EMLVFGKKLTAREACTQGLVTEVFPDSTFQKEV-WVrLKAYSKLPPNAMRISKQVIRNTEKeklHAINAE-----ESNIL 321
Cdd:PRK05995  161 RYFLTAERFDAAEALRLGLVHEVVPAEALDAKVdEL-LAALVANSPQAVRAGKRLVRDVAG---RPIDAAliadtASRIA 236
                         250       260
                  ....*....|....*....|.
gi 1246192453 322 RERwLSDECMNAVVSFLSKKA 342
Cdd:PRK05995  237 LIR-ATEEAREGVAAFLEKRK 256
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
86-342 5.58e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 107.00  E-value: 5.58e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  86 QPGSDALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGD-YYCSGNDLTNFTDIPPG-- 161
Cdd:PRK06144    4 TTSTDELLLEVRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIrAVVLRGAGDkAFVAGTDIAQFRAFSTAed 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 162 GVEEKARSGAVLlrdfvDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSH-LGQspegC-SSYTFPK 239
Cdd:PRK06144   84 AVAYERRIDRVL-----GALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFPIARtLGN----ClSMSNLAR 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 240 I---MGPSKATEMLVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVIRNTEKEKLhainAE 316
Cdd:PRK06144  155 LvalLGAARVKDMLFTARLLEAEEALAAGLVNEVVEDAALDARADALAELLAAHAPLTLRATKEALRRLRREGL----PD 230
                         250       260
                  ....*....|....*....|....*.
gi 1246192453 317 ESNILRERWLSDECMNAVVSFLSKKA 342
Cdd:PRK06144  231 GDDLIRMCYMSEDFREGVEAFLEKRP 256
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
92-312 1.02e-26

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 106.00  E-value: 1.02e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  92 LVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDS-AITVLTGNGDYYCSGNDLTnftdippggvEEKARSG 170
Cdd:PRK09674    4 LLVSRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSiGVCVITGNARFFAAGADLN----------EMAEKDL 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 171 AVLLRD----FVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKA 246
Cdd:PRK09674   74 AATLNDprpqLWQRLQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLA 153
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1246192453 247 TEMLVFGKKLTAREACTQGLVTEVFPDS-TFQKEVWVRlKAYSKLPPNAMRISKQVIRNTEKEKLHA 312
Cdd:PRK09674  154 SQMVLTGESITAQQAQQAGLVSEVFPPElTLERALQLA-SKIARHSPLALRAAKQALRQSQEVDLQA 219
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
89-305 1.19e-26

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 106.00  E-value: 1.19e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  89 SDALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDY-YCSGNDLTNFTDippggveEK 166
Cdd:PRK05980    2 TDTVLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVrAVILTGAGDRaFSAGADIHEFSA-------SV 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 167 ARSGAVLLRDFV-------DRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPK 239
Cdd:PRK05980   75 AAGADVALRDFVrrgqamtARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPR 154
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1246192453 240 IMGPSKATEMLVFGKKLTAREACTQGLVTEVFPdstfqkevwvrlkaYSKLPPNAMRISKQVIRNT 305
Cdd:PRK05980  155 LAGRKRALELLLTGDAFSAERALEIGLVNAVVP--------------HEELLPAARALARRIIRHS 206
PLN02921 PLN02921
naphthoate synthase
98-342 9.48e-26

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 105.25  E-value: 9.48e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  98 DGITTITLNRPDKKNALTTQMYHDIMLALEAAsKDDSAITV--LTGNGD-YYCSGNDLTNFTDIPPGGVEEKARSGAVLL 174
Cdd:PLN02921   75 EGIAKITINRPERRNAFRPRTVKELQRAFNDA-RDDSSVGViiLTGKGTkAFCSGGDQAVRGKDGYVGPDDAGRLNVLDL 153
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 175 RDFVDRFidfPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEMLVFGK 254
Cdd:PLN02921  154 QIQIRRL---PKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMWFLAR 230
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 255 KLTAREACTQGLVTEVFPDSTFQKE--VWVRlkAYSKLPPNAMRISKQvirntekeklhAINAEES----------NILR 322
Cdd:PLN02921  231 FYTASEALKMGLVNTVVPLDELEGEtvKWCR--EILRNSPTAIRVLKS-----------ALNAADDghaglqelggNATL 297
                         250       260
                  ....*....|....*....|
gi 1246192453 323 ERWLSDECMNAVVSFLSKKA 342
Cdd:PLN02921  298 LFYGSEEGNEGRTAYLEGRA 317
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
94-302 1.07e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 100.89  E-value: 1.07e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  94 VTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDY-YCSGNDLTNFTDIPPGGVEEKARSGa 171
Cdd:PRK06494    8 VERKGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQwVAIVTGAGDKaFSAGNDLKEQAAGGKRGWPESGFGG- 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 172 vllrdFVDRFiDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEMLV 251
Cdd:PRK06494   87 -----LTSRF-DLDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMIL 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1246192453 252 FGKKLTAREACTQGLVTEVFPDSTFQKEV--WVRLKAysKLPPNAMRISKQVI 302
Cdd:PRK06494  161 TGRRVTAREGLELGFVNEVVPAGELLAAAerWADDIL--ACSPLSIRASKQAV 211
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
89-342 1.76e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 100.07  E-value: 1.76e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  89 SDALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDS--AItVLTGNGDYYCSGNDLTNFTDIPPGGVEEK 166
Cdd:PRK07511    2 SAELLSRREGSTLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSirAV-VLTGAGGFFCAGGNLNRLLENRAKPPSVQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 167 ARSGAvLLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKA 246
Cdd:PRK07511   81 AASID-GLHDWIRAIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARALPRQLA 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 247 TEMLVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVIRNTEKEKLHAINAEESNILRERWL 326
Cdd:PRK07511  160 TELLLEGKPISAERLHALGVVNRLAEPGQALAEALALADQLAAGSPNALARIKSLIADAPEATLAAQLEAERDHFVASLH 239
                         250
                  ....*....|....*.
gi 1246192453 327 SDECMNAVVSFLSKKA 342
Cdd:PRK07511  240 HADALEGIAAFLEKRA 255
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
88-275 2.57e-24

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 99.79  E-value: 2.57e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  88 GSDALVvtSQDGITTI-TLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLTNFTDIPPGgveE 165
Cdd:PRK07799    4 GPHALV--EQRGHTLIvTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIrSCILTGAGGAFCAGMDLKAATKKPPG---D 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 166 KARSGAV-------LLRDFVDRfidfpKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFP 238
Cdd:PRK07799   79 SFKDGSYdpsridaLLKGRRLT-----KPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLV 153
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1246192453 239 KIMGPSKATEMLVFGKKLTAREACTQGLVTEVFPDST 275
Cdd:PRK07799  154 RQIPYTVACDLLLTGRHITAAEAKEIGLIGHVVPDGQ 190
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
89-312 6.08e-24

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 98.89  E-value: 6.08e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  89 SDALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSAI--TVLTGNGDYYCSGNDLTNFTD------IPP 160
Cdd:PRK09245    2 TDFLLVERDGHIVTLTMNRPETRNALSDNDAVDALVAACAAINADRSVraVILTGAGTAFSSGGNVKDMRArvgafgGSP 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 161 GGVEEKARSGavlLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKI 240
Cdd:PRK09245   82 ADIRQGYRHG---IQRIPLALYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRI 158
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1246192453 241 MGPSKATEMLVFGKKLTAREACTQGLVTEVFPDSTF---QKEVWVRLKAYsklPPNAMRISKQVIRntekEKLHA 312
Cdd:PRK09245  159 IGMARAAEMAFTGDAIDAATALEWGLVSRVVPADQLlpaARALAERIAAN---PPHALRLTKRLLR----EGQHA 226
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
97-274 1.01e-23

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 98.50  E-value: 1.01e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  97 QDGITTITLNRPDKKNALTTQMY---HDIMLALEAAskDDSAITVLTGNGDYYCSGNDltnftdippggVEE-----KAR 168
Cdd:PRK08258   24 DDGVATITLNRPERKNPLTFESYaelRDLFRELVYA--DDVKAVVLTGAGGNFCSGGD-----------VHEiigplTKM 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 169 SGAVLLR------DFVDRFIDFPKPLVAVVNGPAVGISvTILGLF-DIVYATDRATFHTPFSHLGQSpeGC---SSYTFP 238
Cdd:PRK08258   91 DMPELLAftrmtgDLVKAMRACPQPIIAAVDGVCAGAG-AILAMAsDLRLGTPSAKTAFLFTRVGLA--GAdmgACALLP 167
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1246192453 239 KIMGPSKATEMLVFGKKLTAREACTQGLVTEVFPDS 274
Cdd:PRK08258  168 RIIGQGRASELLYTGRSMSAEEGERWGFFNRLVEPE 203
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
97-306 2.10e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 97.72  E-value: 2.10e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  97 QDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDS-AITVLTGNGDYYCSGNDLTNFTDIPPGGVEEKARsgAVLLR 175
Cdd:PRK08290   11 AGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAvRVIVLAGAGKHFSAGHDLGSGTPGRDRDPGPDQH--PTLWW 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 176 DFVD--------------------RFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSpeGCSSY 235
Cdd:PRK08290   89 DGATkpgveqryarewevylgmcrRWRDLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRMGIP--GVEYF 166
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1246192453 236 TFPKIMGPSKATEMLVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVIRNTE 306
Cdd:PRK08290  167 AHPWELGPRKAKELLFTGDRLTADEAHRLGMVNRVVPRDELEAETLELARRIAAMPPFGLRLTKRAVNQTL 237
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
90-303 3.87e-23

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 97.00  E-value: 3.87e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  90 DALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLTNF---TDIPPGGVEE 165
Cdd:PRK09120    8 DTVKVEVEDGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAgVLVLTGAGDAWSAGMDLKEYfreTDAQPEILQE 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 166 KARSGAV----LLRdfvdrfiDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIM 241
Cdd:PRK09120   88 RIRREAYgwwrRLR-------WYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTV 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1246192453 242 GPSKATEMLVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVIR 303
Cdd:PRK09120  161 GHRDALYYIMTGETFTGRKAAEMGLVNESVPLAQLRARTRELAAKLLEKNPVVLRAAKDGFK 222
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
92-304 5.90e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 95.96  E-value: 5.90e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  92 LVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEA-ASKDDSAITVLTGNGDY-YCSGNDLTNFTdippGGVEEKARS 169
Cdd:PRK07657    6 SVDYVTPHVVKITLNRPRAANALSLALLEELQNILTQiNEEANVRVVILTGAGEKaFCAGADLKERA----GMNEEQVRH 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 170 GAVLLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEM 249
Cdd:PRK07657   82 AVSLIRTTMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKEL 161
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1246192453 250 LVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVIRN 304
Cdd:PRK07657  162 IYTGRRISAQEAKEIGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRQAKEAISN 216
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
90-342 2.96e-22

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 93.98  E-value: 2.96e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  90 DALV-VTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLTNFTDiPPGGVEEKA 167
Cdd:PRK07827    5 DTLVrYAVDGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVrAVVLTHTGGTFCAGADLSEAGG-GGGDPYDAA 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 168 RSGAVLLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKiMGPSKAT 247
Cdd:PRK07827   84 VARAREMTALLRAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPR-LSPRAAA 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 248 EMLVFGKKLTAREACTQGLVTEVFPDSTfqKEVWVRLKAYSKLPPNAMRISKQ-----VIRNTEK--EKLhainAEESNI 320
Cdd:PRK07827  163 RYYLTGEKFGAAEAARIGLVTAAADDVD--AAVAALLADLRRGSPQGLAESKAlttaaVLAGFDRdaEEL----TEESAR 236
                         250       260
                  ....*....|....*....|..
gi 1246192453 321 LrerWLSDECMNAVVSFLSKKA 342
Cdd:PRK07827  237 L---FVSDEAREGMTAFLQKRP 255
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
94-301 5.03e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 93.16  E-value: 5.03e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  94 VTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSAITVLTGNGDYYCSGNDLtnftdippggveekarSGAVL 173
Cdd:PRK07854    4 VTRDGQVLTIELQRPERRNALNAELCEELREAVRKAVDESARAIVLTGQGTVFCAGADL----------------SGDVY 67
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 174 LRDFVDRFIDF-------PKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKA 246
Cdd:PRK07854   68 ADDFPDALIEMlhaidaaPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALDNWTIRRLSSLVGGGRA 147
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1246192453 247 TEMLVFGKKLTAREACTQGLVTEVFPDSTFQKevWVRLKAysKLPPNAMRISKQV 301
Cdd:PRK07854  148 RAMLLGAEKLTAEQALATGMANRIGTLADAQA--WAAEIA--GLAPLALQHAKRV 198
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
92-317 5.11e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 93.56  E-value: 5.11e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  92 LVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSAITVLTGNGDYYCSGNDLTNFTDIppgGVEEKARSGA 171
Cdd:PRK07659    8 VVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKEVAESSAHIVVLRGNGRGFSAGGDIKMMLSS---NDESKFDGVM 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 172 VLLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEMLV 251
Cdd:PRK07659   85 NTISEIVVTLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGENKAKQIIW 164
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1246192453 252 FGKKLTAREACTQGLVTEVFpDSTFQKEVWVRLKAYSKLPPNAMRISKQVIRNTEKEKLHAINAEE 317
Cdd:PRK07659  165 EGKKLSATEALDLGLIDEVI-GGDFQTAAKQKISEWLQKPLKAMIETKQIYCELNRSQLEQVLQLE 229
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
89-306 5.52e-22

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 93.61  E-value: 5.52e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  89 SDALVVTSQDGITTITLNRPdKKNAL---TTQMYHDIMLALeaasKDDSAITV--LTGNGD-YYCSGNDLTNFT------ 156
Cdd:PRK03580    2 SESLHTTRNGSILEITLDRP-KANAIdakTSFAMGEVFLNF----RDDPELRVaiITGAGEkFFSAGWDLKAAAegeapd 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 157 -DIPPGGVeekarSGAVLLRDFvdrfidfPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSY 235
Cdd:PRK03580   77 aDFGPGGF-----AGLTEIFDL-------DKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVL 144
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1246192453 236 TFPKIMGPSKATEMLVFGKKLTAREACTQGLVTEVFPDSTFQKEVW--VRLKAYSklPPNAMRISKQVIRNTE 306
Cdd:PRK03580  145 RLPKRLPPAIANEMVMTGRRMDAEEALRWGIVNRVVPQAELMDRARelAQQLVNS--APLAIAALKEIYRETS 215
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
89-307 6.33e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 93.62  E-value: 6.33e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  89 SDALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGD-YYCSGNDLTNFtdippggveEK 166
Cdd:PRK06127   10 TGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIrVVVLTGAGEkAFVSGADISQF---------EE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 167 ARSGAVLLRDFVDR-------FIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPK 239
Cdd:PRK06127   81 SRSDAEAVAAYEQAveaaqaaLADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVD 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1246192453 240 IMGPSKATEMLVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVIRNTEK 307
Cdd:PRK06127  161 LVGPSAAKDLFYTARRFDAAEALRIGLVHRVTAADDLETALADYAATIAGNAPLTLRAAKRAIAELLK 228
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
81-300 7.36e-22

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 93.08  E-value: 7.36e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  81 AADRKQPGSDALVVTS-QDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLTnftdi 158
Cdd:PRK08139    1 MMAPAAATEAPLLLREdRDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVrVVVLAAAGKAFCAGHDLK----- 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 159 ppggvEEKARSGAVLLRDFVDRFIDF-------PKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSpeg 231
Cdd:PRK08139   76 -----EMRAARGLAYFRALFARCSRVmqaivalPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLF--- 147
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1246192453 232 CSSytfPKI-----MGPSKATEMLVFGKKLTAREACTQGLVTEVFPDSTFQKEVwVRLKAY--SKlPPNAMRISKQ 300
Cdd:PRK08139  148 CST---PMValsrnVPRKQAMEMLLTGEFIDAATAREWGLVNRVVPADALDAAV-ARLAAViaAK-SPAAVRIGKE 218
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
87-272 7.68e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 93.11  E-value: 7.68e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  87 PGSDALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLtnftdippggvEE 165
Cdd:PRK06190    1 MTEPILLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVdVVVLTGADPAFCAGLDL-----------KE 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 166 KARSGAVLLRDFVDRFID-----FPKPLVAVVNGPAV--GISVTiLGLfDIVYATDRATFHTPFSHLGQSPEGCSSYTFP 238
Cdd:PRK06190   70 LGGDGSAYGAQDALPNPSpawpaMRKPVIGAINGAAVtgGLELA-LAC-DILIASERARFADTHARVGILPGWGLSVRLP 147
                         170       180       190
                  ....*....|....*....|....*....|....
gi 1246192453 239 KIMGPSKATEMLVFGKKLTAREACTQGLVTEVFP 272
Cdd:PRK06190  148 QKVGIGRARRMSLTGDFLDAADALRAGLVTEVVP 181
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
92-343 9.66e-22

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 92.89  E-value: 9.66e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  92 LVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSAITV-LTGNGD-YYCSGNDLTNFTDIppggVEEKARS 169
Cdd:PRK05809    6 VILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAViLTGAGEkAFVAGADISEMKDL----NEEEGRK 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 170 GAVLLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEM 249
Cdd:PRK05809   82 FGLLGNKVFRKLENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPGKAKEL 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 250 LVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVIRNTEKEKLHAINAEESNILRERWLSDE 329
Cdd:PRK05809  162 IYTGDMINAEEALRIGLVNKVVEPEKLMEEAKALANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAEDFGECFSTED 241
                         250
                  ....*....|....
gi 1246192453 330 CMNAVVSFLSKKAK 343
Cdd:PRK05809  242 QTEGMTAFVEKREK 255
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
90-341 1.30e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 92.39  E-value: 1.30e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  90 DALVVTSQDGITTITLNRPdKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLTNFTDIPPGG-VEEKA 167
Cdd:PRK07658    2 KFLSVRVEDHVAVITLNHP-PANALSSQVLHELSELLDQVEKDDNVrVVVIHGEGRFFSAGADIKEFTSVTEAEqATELA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 168 RSGAVLLrdfvDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKAT 247
Cdd:PRK07658   81 QLGQVTF----ERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKAL 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 248 EMLVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVIRNTEKEKLHAINAEESNILRERWLS 327
Cdd:PRK07658  157 EMMLTSEPITGAEALKWGLVNGVFPEETLLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFTS 236
                         250
                  ....*....|....
gi 1246192453 328 DECMNAVVSFLSKK 341
Cdd:PRK07658  237 EDAKEGVQAFLEKR 250
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
92-302 6.85e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 90.50  E-value: 6.85e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  92 LVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDS--AItVLTGNGDYYCSGNDLTNFTDippggveekARS 169
Cdd:PRK08138   10 LLERPADGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDirAI-VLTGGEKVFAAGADIKEFAT---------AGA 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 170 GAVLLRDfVDRFID----FPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSK 245
Cdd:PRK08138   80 IEMYLRH-TERYWEaiaqCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFK 158
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1246192453 246 ATEMLVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVI 302
Cdd:PRK08138  159 AMRMALTGCMVPAPEALAIGLVSEVVEDEQTLPRALELAREIARMPPLALAQIKEVV 215
ACBP pfam00887
Acyl CoA binding protein;
20-65 1.33e-20

Acyl CoA binding protein;


Pssm-ID: 459982  Cd Length: 76  Bit Score: 84.19  E-value: 1.33e-20
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1246192453  20 KQATEGPCNVPKPGVLDFINKAKWDAWNALGSLPKETARHNYVDLV 65
Cdd:pfam00887  31 KQATVGDCNTPRPGMFDFKGKAKWDAWKKLGGMSKEEAMAKYVELV 76
PLN02888 PLN02888
enoyl-CoA hydratase
92-307 2.61e-20

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 89.04  E-value: 2.61e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  92 LVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDS-AITVLTGNGDYYCSGNDLTNFTDIPPGGVEEKArsg 170
Cdd:PLN02888   12 LVPKSRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSvKVIILTGSGRAFCSGVDLTAAEEVFKGDVKDVE--- 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 171 avllRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEML 250
Cdd:PLN02888   89 ----TDPVAQMERCRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVS 164
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1246192453 251 VFGKKLTAREACTQGLVTEVFPDstfqkevwvrlkaySKLPPNAMRISKQVIRNTEK 307
Cdd:PLN02888  165 LTAMPLTAETAERWGLVNHVVEE--------------SELLKKAREVAEAIIKNNQG 207
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
97-302 4.73e-20

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 87.20  E-value: 4.73e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  97 QDGITTITLNRPdKKNALTTQMYHDIMLAL-EAASKDDSAITVLTGNGDYYCSGNDLTNFTDIPPggveEKARSGAVLLR 175
Cdd:PRK05869   15 DAGLATLLLSRP-PTNALTRQVYREIVAAAnELGRRDDVAAVILYGGHEIFSAGDDMPELRTLSA----QEADTAARVRQ 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 176 DFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEMLVFGKK 255
Cdd:PRK05869   90 QAVDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAGPSRAKELVFSGRF 169
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1246192453 256 LTAREACTQGLVTE-VFPDSTFQKEV-WVRlkAYSKLPPNAMRISKQVI 302
Cdd:PRK05869  170 FDAEEALALGLIDEmVAPDDVYDAAAaWAR--RFLDGPPHALAAAKAGI 216
ACBP cd00435
Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a ...
9-65 6.53e-20

Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a role in regulation of intermediary metabolism and gene regulation. The suggested role of ACBP is to act as a intracellular acyl-CoA transporter and pool former. ACBPs are present in a large group of eukaryotic species and several tissue-specific isoforms have been detected.


Pssm-ID: 238248  Cd Length: 85  Bit Score: 82.76  E-value: 6.53e-20
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1246192453   9 NEAKKERKGWMKQATEGPCNVPKPGVLDFINKAKWDAWNALGSLPKETARHNYVDLV 65
Cdd:cd00435    21 NEEKLQLYSLYKQATVGDCNTERPGMFDLKGRAKWDAWNSLKGMSKEDAMKAYIAKV 77
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
90-342 6.75e-20

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 87.44  E-value: 6.75e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  90 DALVVTSQDGITTITLNRPdKKNALTTQMYHDIMLALEAAS-KDDSAITVLTGNGDYYCSGNDLTNFTDI--PPGGVEEK 166
Cdd:PRK06495    4 SQLKLEVSDHVAVVTLDNP-PVNALSRELRDELIAVFDEISeRPDVRVVVLTGAGKVFCAGADLKGRPDVikGPGDLRAH 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 167 ARsgavLLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSpEGCSSYTfpKIMGPSKA 246
Cdd:PRK06495   83 NR----RTRECFHAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGLA-GGGKHAM--RLFGHSLT 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 247 TEMLVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVIRNTEKEKLHAINAEESNILRERWL 326
Cdd:PRK06495  156 RRMMLTGYRVPAAELYRRGVIEACLPPEELMPEAMEIAREIASKSPLATRLAKDALNTIENMSLRDGYRYEQDITAKLAK 235
                         250
                  ....*....|....*.
gi 1246192453 327 SDECMNAVVSFLSKKA 342
Cdd:PRK06495  236 TEDAKEAQRAFLEKRP 251
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
93-273 9.36e-20

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 86.94  E-value: 9.36e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  93 VVTSQDG-ITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLTNF--------TDIPPGG 162
Cdd:PRK06563    1 VSRERRGhVLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELrVAVLFAHGEHFTAGLDLADVapklaaggFPFPEGG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 163 VEEKARSGAVLlrdfvdrfidfPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMG 242
Cdd:PRK06563   81 IDPWGTVGRRL-----------SKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAG 149
                         170       180       190
                  ....*....|....*....|....*....|.
gi 1246192453 243 PSKATEMLVFGKKLTAREACTQGLVTEVFPD 273
Cdd:PRK06563  150 WGNAMRYLLTGDEFDAQEALRLGLVQEVVPP 180
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
99-271 4.92e-18

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 82.64  E-value: 4.92e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  99 GITTITLNRPDKKNALTTQMYHDIMLALEAASKD-DSAITVLTGNGDYYCSGNDLTNFTDIPP-GGVEEKARSGAVLLRD 176
Cdd:PLN02664   17 SVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNpNVSVIILSGAGDHFCSGIDLKTLNSISEqSSSGDRGRSGERLRRK 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 177 --FVDRFI----DFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEML 250
Cdd:PLN02664   97 ikFLQDAItaieQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGNAMELA 176
                         170       180
                  ....*....|....*....|.
gi 1246192453 251 VFGKKLTAREACTQGLVTEVF 271
Cdd:PLN02664  177 LTGRRFSGSEAKELGLVSRVF 197
PLN02600 PLN02600
enoyl-CoA hydratase
99-317 5.81e-18

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 82.16  E-value: 5.81e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  99 GITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSAITVLTGNG--DYYCSGNDLTNFTDIPPGGVEEKARSgavlLRD 176
Cdd:PLN02600    4 GIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSvpGVFCAGADLKERRKMSPSEVQKFVNS----LRS 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 177 FVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEMLVFGKKL 256
Cdd:PLN02600   80 TFSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRI 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1246192453 257 TAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVI-RNTEKEKLHAINAEE 317
Cdd:PLN02600  160 GAREAASMGLVNYCVPAGEAYEKALELAQEINQKGPLAIKMAKKAInEGSEVDMASGLEIEE 221
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
92-267 1.02e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 81.36  E-value: 1.02e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  92 LVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKD-DSAITVLTGNGDYYCSGNDLTNFT-DIppggveekars 169
Cdd:PRK06072    2 IKVESREGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADpKIRVVIVTGEGRAFCVGADLSEFApDF----------- 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 170 gAVLLRD-F--VDRFIDFP-KPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGpSK 245
Cdd:PRK06072   71 -AIDLREtFypIIREIRFSdKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTG-QR 148
                         170       180
                  ....*....|....*....|..
gi 1246192453 246 ATEMLVFGKKLTAREACTQGLV 267
Cdd:PRK06072  149 FYEILVLGGEFTAEEAERWGLL 170
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
91-273 1.17e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 81.56  E-value: 1.17e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  91 ALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLTNFTDI-PPGGVEEKAR 168
Cdd:PRK06142    7 SFTVELADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVrAVVLSGSGKHFSYGIDLPAMAGVfGQLGKDGLAR 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 169 SGAVLLR------DFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMG 242
Cdd:PRK06142   87 PRTDLRReilrlqAAINAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPRIIG 166
                         170       180       190
                  ....*....|....*....|....*....|.
gi 1246192453 243 PSKATEMLVFGKKLTAREACTQGLVTEVFPD 273
Cdd:PRK06142  167 DGHLRELALTGRDIDAAEAEKIGLVNRVYDD 197
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
90-318 2.66e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 80.31  E-value: 2.66e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  90 DALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSAITV-LTGNGDYYCSGNDLTNFTDIPPGGVE---E 165
Cdd:PRK07509    3 DRVSVTIEDGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAViLSGEGGAFCAGLDVKSVASSPGNAVKllfK 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 166 KARSGAVLLRDFVDRFIDFPKPLVAVVNGPAVGISVTI-LGLfDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPS 244
Cdd:PRK07509   83 RLPGNANLAQRVSLGWRRLPVPVIAALEGVCFGGGLQIaLGA-DIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGLVRKD 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 245 KATEMLVFGKKLTAREACTQGLVTEVFPDStfqkevwvRLKAY------SKLPPNAMRISKQVIRNTEKEKLHAINAEES 318
Cdd:PRK07509  162 VARELTYTARVFSAEEALELGLVTHVSDDP--------LAAALalareiAQRSPDAIAAAKRLINRSWTASVRALLARES 233
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
92-289 1.34e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 78.72  E-value: 1.34e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  92 LVVTSQDGITTITLNRPDKKNAlttqMYHDIML----ALEAASKDDSA-ITVLTGNGDYYCSGNDLTNFTDIPP-GGVEE 165
Cdd:PRK05864   12 LVDHPRPEIALITLNRPERMNS----MAFDVMVplkeALAEVSYDNSVrVVVLTGAGRGFSSGADHKSAGVVPHvEGLTR 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 166 KARS--GAVLLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLG-QSPEGCSSYTFPKIMG 242
Cdd:PRK05864   88 PTYAlrSMELLDDVILALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGlTASELGLSYLLPRAIG 167
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1246192453 243 PSKATEMLVFGKKLTAREACTQGLVTEVFPDSTFQKEVW---VRLKAYSK 289
Cdd:PRK05864  168 SSRAFEIMLTGRDVDAEEAERIGLVSRQVPDEQLLDTCYaiaARMAGFSR 217
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
97-306 1.64e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 77.86  E-value: 1.64e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  97 QDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLTNFTDippgGVEEKARSGAVLLR 175
Cdd:PRK07260    9 EDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVrFLLINANGKVFSVGGDLVEMKR----AVDEDDVQSLVKIA 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 176 DFVDRfIDF-----PKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSKATEML 250
Cdd:PRK07260   85 ELVNE-ISFaikqlPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGLNRATHLA 163
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1246192453 251 VFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVIRNTE 306
Cdd:PRK07260  164 MTGEALTAEKALEYGFVYRVAESEKLEKTCEQLLKKLRRGSSNSYAAIKSLVWESF 219
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
92-272 1.47e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 75.46  E-value: 1.47e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  92 LVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDS--AItVLTGNGDYYCSGNDLT-----NFTDippggve 164
Cdd:PRK05862    6 ILVETRGRVGLITLNRPKALNALNDALMDELGAALAAFDADEGigAI-VITGSEKAFAAGADIKemadlSFMD------- 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 165 ekarsgaVLLRDFV---DRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIM 241
Cdd:PRK05862   78 -------VYKGDYItnwEKVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAV 150
                         170       180       190
                  ....*....|....*....|....*....|.
gi 1246192453 242 GPSKATEMLVFGKKLTAREACTQGLVTEVFP 272
Cdd:PRK05862  151 GKAKAMDLCLTGRMMDAAEAERAGLVSRVVP 181
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
99-341 4.32e-15

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 74.07  E-value: 4.32e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  99 GITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDL------------TNFTDippggvee 165
Cdd:PRK05674   15 GFATLWLSRADKNNAFNAQMIRELILALDQVQSDASLrFLLLRGRGRHFSAGADLawmqqsadldynTNLDD-------- 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 166 kARSGAVLLRdfvdRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFpKIMGPSK 245
Cdd:PRK05674   87 -ARELAELMY----NLYRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISPFVV-KAIGERA 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 246 ATEMLVFGKKLTAREACTQGLVTEVFPDSTF--QKEVWV-RLKAYSklpPNAMRISKQVIRNTEKEKLHAI--NAEESNI 320
Cdd:PRK05674  161 ARRYALTAERFDGRRARELGLLAESYPAAELeaQVEAWIaNLLLNS---PQALRASKDLLREVGDGELSPAlrRYCENAI 237
                         250       260
                  ....*....|....*....|.
gi 1246192453 321 LRERwLSDECMNAVVSFLSKK 341
Cdd:PRK05674  238 ARIR-VSAEGQEGLRAFLEKR 257
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
97-302 7.57e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 73.92  E-value: 7.57e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  97 QDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLTNF----TDIPPGGVEEKARSGA 171
Cdd:PRK08272   17 TGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVhVILVSGAGKGFCAGYDLSAYaegsSSGGGGGAYPGKRQAV 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 172 VLLRDFV-DRFIDF----------------PKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHL-GQSPEGCS 233
Cdd:PRK08272   97 NHLPDDPwDPMIDYqmmsrfvrgfmslwhaHKPTVAKVHGYCVAGGTDIALHCDQVIAADDAKIGYPPTRVwGVPATGMW 176
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1246192453 234 SYTfpkiMGPSKATEMLVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVI 302
Cdd:PRK08272  177 AYR----LGPQRAKRLLFTGDCITGAQAAEWGLAVEAVPPEELDERTERLVERIAAVPVNQLAMVKLAV 241
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
89-272 1.38e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 72.33  E-value: 1.38e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  89 SDALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEA-ASKDDSAITVLTGNGDYYCSGNDLTNFT-----DIP--- 159
Cdd:PRK08252    2 SDEVLVERRGRVLIITINRPEARNAVNAAVAQGLAAALDElDADPDLSVGILTGAGGTFCAGMDLKAFArgerpSIPgrg 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 160 PGGVEEKARSgavllrdfvdrfidfpKPLVAVVNGPAVGisvtilGLFDIVYATD------RATFHTPFSHLGQSPEGCS 233
Cdd:PRK08252   82 FGGLTERPPR----------------KPLIAAVEGYALA------GGFELALACDlivaarDAKFGLPEVKRGLVAAGGG 139
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1246192453 234 SYTFPKIMGPSKATEMLVFGKKLTAREACTQGLVTEVFP 272
Cdd:PRK08252  140 LLRLPRRIPYHIAMELALTGDMLTAERAHELGLVNRLTE 178
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
96-272 5.34e-14

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 71.08  E-value: 5.34e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  96 SQDGITTITLNRPDKKNALTTQMYHDIMLALEAAsKDDSAITV--LTGNGDY-YCSGNDltnftdippggveEKAR-SGA 171
Cdd:PRK07396   19 SADGIAKITINRPEVRNAFRPKTVKEMIDAFADA-RDDDNIGViiLTGAGDKaFCSGGD-------------QKVRgYGG 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 172 VLLRDFVDRF--IDF-------PKPLVAVVNGPAVGISVTILGLFDIVYATDRATFhtpfshlGQ------SPEG--CSS 234
Cdd:PRK07396   85 YVDDDGVPRLnvLDLqrlirtcPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIF-------GQtgpkvgSFDGgyGAS 157
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1246192453 235 YtFPKIMGPSKATEMLVFGKKLTAREACTQGLVTEVFP 272
Cdd:PRK07396  158 Y-LARIVGQKKAREIWFLCRQYDAQEALDMGLVNTVVP 194
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
89-272 6.73e-14

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 70.44  E-value: 6.73e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  89 SDALVVTS-QDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSAITVLT--GNGDYYCSGNDLtnfTDIPPGGVEE 165
Cdd:PRK11423    2 SMQYVNVVtINKIATITFNNPAKRNALSKVLIDDLMQALSDLNRPEIRVVILRapSGSKVWSAGHDI---HELPSGGRDP 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 166 KARSGAvlLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFH-TPfSHLGqSPEGCSS-YTFPKIMGP 243
Cdd:PRK11423   79 LSYDDP--LRQILRMIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAmTP-ANLG-VPYNLSGiLNFTNDAGF 154
                         170       180
                  ....*....|....*....|....*....
gi 1246192453 244 SKATEMLVFGKKLTAREACTQGLVTEVFP 272
Cdd:PRK11423  155 HIVKEMFFTASPITAQRALAVGILNHVVE 183
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
98-304 8.10e-14

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 70.44  E-value: 8.10e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  98 DGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLtnftdippGGVEEKARSGAVLLR- 175
Cdd:PRK07327   20 PGVLEIVLNGPGALNAADARMHRELADIWRDVDRDPDVrVVLIRGEGKAFSAGGDL--------ALVEEMADDFEVRARv 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 176 -----DFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATF---HTpfsHLGQSPEGCSSYTFPKIMGPSKAT 247
Cdd:PRK07327   92 wrearDLVYNVINCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIidgHT---RLGVAAGDHAAIVWPLLCGMAKAK 168
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 248 EMLVFGKKLTAREACTQGLVTEVFPDSTFQK---EVWVRLKAYSklpPNAMRISKQVIRN 304
Cdd:PRK07327  169 YYLLLCEPVSGEEAERIGLVSLAVDDDELLPkalEVAERLAAGS---QTAIRWTKYALNN 225
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
93-272 1.13e-13

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 69.61  E-value: 1.13e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  93 VVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSAITV-LTGNGDYYCSGndltnftdippgGVEEKARS-- 169
Cdd:PRK07110    8 LREVEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVViLTGYPNYFATG------------GTQEGLLSlq 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 170 ---GAVLLRDFVDRFIDFPKPLVAVVNGPAVGISVtILGLF-DIVYATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPSK 245
Cdd:PRK07110   76 tgkGTFTEANLYSLALNCPIPVIAAMQGHAIGGGL-VLGLYaDIVVLSRESVYTANFMKYGFTPGMGATAILPEKLGLAL 154
                         170       180
                  ....*....|....*....|....*..
gi 1246192453 246 ATEMLVFGKKLTAREACTQGLVTEVFP 272
Cdd:PRK07110  155 GQEMLLTARYYRGAELKKRGVPFPVLP 181
ACB COG4281
Acyl-CoA-binding protein [Lipid transport and metabolism];
20-65 2.09e-13

Acyl-CoA-binding protein [Lipid transport and metabolism];


Pssm-ID: 443422  Cd Length: 87  Bit Score: 64.87  E-value: 2.09e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1246192453  20 KQATEGPCNVPKPGVLDFINKAKWDAWNALGSLPKETARHNYVDLV 65
Cdd:COG4281    35 KQATEGDVTGKRPGMTDFVGRAKYDAWAQLKGMSKDEAMQQYIDLV 80
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
102-268 1.08e-12

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 68.56  E-value: 1.08e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 102 TITLNRPDKKNALTTQMYHDIMLALEAASKDDS-AITVLTGNGDYYCSGNDLTNFTDIPPGGVEEKARSGAVLLRDFVDR 180
Cdd:PLN02157   49 TAILNRPPALNALTTHMGYRLQKLYKNWEEDPNiGFVMMKGSGRAFCAGGDIVSLYHLRKRGSPDAIREFFSSLYSFIYL 128
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 181 FIDFPKPLVAVVNGPAV--GISVTILGLFDIvyATDRATFHTPFSHLGQSPEGCSSYTFPKImgPSKATEML-VFGKKLT 257
Cdd:PLN02157  129 LGTYLKPHVAILNGVTMggGTGVSIPGTFRV--ATDRTIFATPETIIGFHPDAGASFNLSHL--PGRLGEYLgLTGLKLS 204
                         170
                  ....*....|.
gi 1246192453 258 AREACTQGLVT 268
Cdd:PLN02157  205 GAEMLACGLAT 215
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
80-299 2.74e-12

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 66.59  E-value: 2.74e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  80 PAADRKQPGSDALVVT----SQDGITTITLNRPDKKNALTTQMYHDIMLALEAASK-DDSAITVLTGNGDY-------YC 147
Cdd:PRK08321   11 PDLWRPVPGFDFTDITyhraVDQGTVRIAFDRPEVRNAFRPHTVDELYRALDHARMsPDVGCVLLTGNGPSpkdggwaFC 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 148 SGNDLT-------NFTDIPPGGVEEKARSGAVLLRDfVDRFIDF-PKPLVAVVNGPAVGISVTILGLFDIVYAT-DRATF 218
Cdd:PRK08321   91 SGGDQRirgrdgyQYAEGDEADTVDPARAGRLHILE-VQRLIRFmPKVVIAVVPGWAAGGGHSLHVVCDLTLASrEHARF 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 219 HTPFSHLGQSPEGCSSYTFPKIMGPSKATEMLVFGKKLTAREACTQGLVTEVFPDSTFQKEV--WVRlKAYSKlPPNAMR 296
Cdd:PRK08321  170 KQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYSAEEAHDMGAVNAVVPHAELETEAleWAR-EINGK-SPTAMR 247

                  ...
gi 1246192453 297 ISK 299
Cdd:PRK08321  248 MLK 250
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
89-273 3.51e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 65.69  E-value: 3.51e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  89 SDALVVTSQDGITTITLNRPDKKNAL---TTQMYHDIMLALEAaskDDSA-ITVLTGNGDYYCSGNDLTNFTDippGGVE 164
Cdd:PRK08259    2 SMSVRVERNGPVTTVILNRPEVRNAVdgpTAAALADAFRAFDA---DDAAsVAVLWGAGGTFCAGADLKAVGT---GRGN 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 165 EKARSGavllrdfvD------RFIdFPKPLVAVVNGPAV--GISVTILGlfDIVYATDRATFHT-------PFSHLGqsp 229
Cdd:PRK08259   76 RLHPSG--------DgpmgpsRMR-LSKPVIAAVSGYAVagGLELALWC--DLRVAEEDAVFGVfcrrwgvPLIDGG--- 141
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1246192453 230 egcsSYTFPKIMGPSKATEMLVFGKKLTAREACTQGLVTEVFPD 273
Cdd:PRK08259  142 ----TVRLPRLIGHSRAMDLILTGRPVDADEALAIGLANRVVPK 181
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
89-275 5.50e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 65.04  E-value: 5.50e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  89 SDALVVTSQDGITTITLNRPDKKNALTTqmyhDIMLALEAA---SKDDSAITVLTGNGDYYCSGNDLTNFTDIPPGGVEE 165
Cdd:PRK08150    1 PSLVSYELDGGVATIGLNRPAKRNALND----GLIAALRAAfarLPEGVRAVVLHGEGDHFCAGLDLSELRERDAGEGMH 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 166 KARS-GAVLlrdfvDRFIDFPKPLVAVVNGPAVGisvtilGLFDIVYAT-----DRATFHtpfshlgQSPEGC------- 232
Cdd:PRK08150   77 HSRRwHRVF-----DKIQYGRVPVIAALHGAVVG------GGLELASAAhirvaDESTYF-------ALPEGQrgifvgg 138
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1246192453 233 -SSYTFPKIMGPSKATEMLVFGKKLTAREACTQGLVTEVFPDST 275
Cdd:PRK08150  139 gGSVRVPRLIGVARMTDMMLTGRVYDAQEGERLGLAQYLVPAGE 182
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
87-333 9.01e-12

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 65.59  E-value: 9.01e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  87 PGSDALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLTNFTDippgGVEE 165
Cdd:PLN02874    8 PAEEVVLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVeLIIIKGAGRAFSAGGDLKMFYD----GRES 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 166 KARSGAVLLRDF-VDRFI-DFPKPLVAVVNGPAV--GISVTILGLFDIVyaTDRATFHTPFSHLGQSPEGCSSYTFPKIm 241
Cdd:PLN02874   84 DDSCLEVVYRMYwLCYHIhTYKKTQVALVHGLVMggGAGLMVPMKFRVV--TEKTVFATPEASVGFHTDCGFSYILSRL- 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 242 gPSKATEMLVF-GKKLTAREACTQGLVTEVFPdSTFQKEVWVRLkaySKLPPNAMRISKQVIRNTEKEklhaINAEESNI 320
Cdd:PLN02874  161 -PGHLGEYLALtGARLNGKEMVACGLATHFVP-SEKLPELEKRL---LNLNSGDESAVQEAIEEFSKD----VQADEDSI 231
                         250
                  ....*....|...
gi 1246192453 321 LRERWLSDECMNA 333
Cdd:PLN02874  232 LNKQSWINECFSK 244
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
87-302 1.12e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 64.59  E-value: 1.12e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  87 PGSDALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKD-DSAITVLTGNGDYYCSGNDL---------TNFT 156
Cdd:PRK12478    2 PDFQTLLYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDqDIKVIVLRGAGRAFSGGYDFgggfqhwgeAMMT 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 157 DippGGVEEKARSGAVLLRDF--VDRFIDF---PKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHL-GQSPE 230
Cdd:PRK12478   82 D---GRWDPGKDFAMVTARETgpTQKFMAIwraSKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYSRMwGAYLT 158
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1246192453 231 GCSSYTfpkiMGPSKATEMLVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVI 302
Cdd:PRK12478  159 GMWLYR----LSLAKVKWHSLTGRPLTGVQAAEAELINEAVPFERLEARVAEVATELARIPLSQLQAQKLIV 226
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
105-268 1.42e-11

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 65.00  E-value: 1.42e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 105 LNRPDKKNALTTQMYHDIMLALEAASKD-DSAITVLTGNGDYYCSGNDLTNFTDIPPGGVEEKARSGAVLLRDFVDRFID 183
Cdd:PLN02851   57 LNRPSSLNALTIPMVARLKRLYESWEENpDIGFVLMKGSGRAFCSGADVVSLYHLINEGNVEECKLFFENLYKFVYLQGT 136
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 184 FPKPLVAVVNGPAVGI--SVTILGLFDIVyaTDRATFHTPFSHLGQSPEGCSSYTFPKImgPSKATEMLVF-GKKLTARE 260
Cdd:PLN02851  137 YLKPNVAIMDGITMGCgaGISIPGMFRVV--TDKTVFAHPEVQMGFHPDAGASYYLSRL--PGYLGEYLALtGQKLNGVE 212

                  ....*...
gi 1246192453 261 ACTQGLVT 268
Cdd:PLN02851  213 MIACGLAT 220
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
102-221 1.96e-11

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 64.03  E-value: 1.96e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 102 TITLNRPDKKNALTTQMYHDIMLALEAASKDDS-AITVLTGNGDY-YCSGNDLTNFTDippGGVEEKARSGAVLLRDF-- 177
Cdd:pfam16113   3 VITLNRPKALNALNLEMVRALLAALKAWEDDPAvKLVVLKGAGERaFCAGGDVRALYE---AAKAGGGEAGRDFFREEyr 79
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1246192453 178 VDRFI-DFPKPLVAVVN----GPAVGISVTilGLFDIVyaTDRATFHTP 221
Cdd:pfam16113  80 LNYLIaTYPKPYVALMDgivmGGGVGLSVH--GSFRVV--TERTRFAMP 124
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
92-274 6.09e-11

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 62.81  E-value: 6.09e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  92 LVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLTNFT-DIPPGgveeKARS 169
Cdd:PLN02988   11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVkLVILKGHGRAFCAGGDVAAVVrDIEQG----NWRL 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 170 GAVLLRD-FVDRFI--DFPKPLVAVVNGPAV--GISVTILGLFDIvyATDRATFHTPFSHLGQSPEGCSSYTFPKIMGPS 244
Cdd:PLN02988   87 GANFFSDeYMLNYVmaTYSKAQVSILNGIVMggGAGVSVHGRFRI--ATENTVFAMPETALGLFPDVGASYFLSRLPGFF 164
                         170       180       190
                  ....*....|....*....|....*....|
gi 1246192453 245 KATEMLVfGKKLTAREACTQGLVTEVFPDS 274
Cdd:PLN02988  165 GEYVGLT-GARLDGAEMLACGLATHFVPST 193
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
89-200 1.34e-10

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 61.76  E-value: 1.34e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  89 SDALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAASKDDS-AITVLTGNGDY-YCSGNDLTnftdippgGVEEK 166
Cdd:PRK05617    2 EDEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAvAAVVIEGAGERgFCAGGDIR--------ALYEA 73
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1246192453 167 ARSGAVLLRD--FVDRFI------DFPKPLVA----VVNGPAVGIS 200
Cdd:PRK05617   74 ARAGDPLAADrfFREEYRlnaliaRYPKPYIAlmdgIVMGGGVGIS 119
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
95-272 3.43e-09

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 56.52  E-value: 3.43e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  95 TSQDGITTITLNRPdKKNALTTQMYHDIMLALEAASKDDSA-ITVLTGNGDYYCSGNDLTnftdippggvEEKARSGAVL 173
Cdd:PRK07938    7 TPEPGIAEVTVDYP-PVNALPSAGWFALADAITAAGADPDTrVVVLRAEGRGFNAGVDIK----------ELQATPGFTA 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 174 LRDfVDR--FIDF------PKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTP---------FSHLGQspegcssyt 236
Cdd:PRK07938   76 LID-ANRgcFAAFravyecAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPevdrgalgaATHLQR--------- 145
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1246192453 237 fpkiMGPSKATEMLVF-GKKLTAREACTQGLVTEVFP 272
Cdd:PRK07938  146 ----LVPQHLMRALFFtAATITAAELHHFGSVEEVVP 178
PRK06213 PRK06213
crotonase/enoyl-CoA hydratase family protein;
89-197 9.98e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235744  Cd Length: 229  Bit Score: 54.98  E-value: 9.98e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  89 SDALVVTSQDGITTITLNRpDKKNALTTQMYHDIMLALEAASkDDSAITVLTGNGDYYCSGNDLTNFTDIPPGGVeEKAR 168
Cdd:PRK06213    2 SELVSYTLEDGVATITLDD-GKVNALSPAMIDALNAALDQAE-DDRAVVVITGQPGIFSGGFDLKVMTSGAQAAI-ALLT 78
                          90       100
                  ....*....|....*....|....*....
gi 1246192453 169 SGAVLLRdfvdRFIDFPKPLVAVVNGPAV 197
Cdd:PRK06213   79 AGSTLAR----RLLSHPKPVIVACTGHAI 103
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
91-310 2.22e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 54.27  E-value: 2.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  91 ALVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEA-ASKDDSAITVLTGNGDY-YCSGNDLTNFTDIPPggveEKAR 168
Cdd:PRK06143    8 AGVTRDDRGVATLTIRNAGSLNILGTPVILALTQALRWlAADPDVRVLVLRGAGEKaFIGGADIKEMATLDQ----ASAE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 169 SGAVLLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGqSPEGCSSYTFPKIMGPSKATE 248
Cdd:PRK06143   84 AFISRLRDLCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVG-IPSVIHAALLPRLIGWARTRW 162
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1246192453 249 MLVFGKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVIRNTEKEKL 310
Cdd:PRK06143  163 LLLTGETIDAAQALAWGLVDRVVPLAELDAAVERLAASLAGCGPQALRQQKRLLREWEDMPL 224
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
97-274 6.31e-08

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 54.13  E-value: 6.31e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  97 QDGITTITLNRPDKK-NALTTQMYHDImLALEAASKDDSAITVL---TGNGDYYCSGNDLTNFTDIPPGG-VEEKARSGA 171
Cdd:PRK11154   13 EDNIAVITIDVPGEKmNTLKAEFAEQV-RAILKQLREDKELKGVvfiSGKPDNFIAGADINMLAACKTAQeAEALARQGQ 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 172 VLLrdfvDRFIDFPKPLVAVVNGPAVG----------------ISVTILGLfdivyatdratfhtPFSHLGQSPEGCSSY 235
Cdd:PRK11154   92 QLF----AEIEALPIPVVAAIHGACLGgglelalachyrvctdDPKTVLGL--------------PEVQLGLLPGSGGTQ 153
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1246192453 236 TFPKIMGPSKATEMLVFGKKLTAREACTQGLVTEVFPDS 274
Cdd:PRK11154  154 RLPRLIGVSTALDMILTGKQLRAKQALKLGLVDDVVPHS 192
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
99-317 8.63e-08

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 52.57  E-value: 8.63e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  99 GITTITLNRpDKKNALTTQMYHDIMLALEAASKDDSAITVLTGNG---DYYCSGNDLTNFTdiPPGGVEEKARSGAVLLR 175
Cdd:PLN03214   21 GIAVVWLAK-EPVNSMTLAMWRSLDDALTALENDPTVRGVVFASGlrrDVFTAGNDIAELY--APKTSAARYAEFWLTQT 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 176 DFVDRFIDFPKPLVAVVNG--PAVGISVTILGlfDIVYATDRATFHTPFSHLG-QSPEGCSSYTFPKIMGPSKATEMLVF 252
Cdd:PLN03214   98 TFLVRLLRSRLATVCAIRGacPAGGCAVSLCC--DYRLQTTEGTMGLNEVALGiPVPKFWARLFMGRVIDRKVAESLLLR 175
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1246192453 253 GKKLTAREACTQGLVTEVFPDSTFQKEVWVRLKAYSKLPPNAMRISKQVIRNTEKEKLHAINAEE 317
Cdd:PLN03214  176 GRLVRPAEAKQLGLIDEVVPAAALMEAAASAMERALKLPSAARAATKALLREEFSAAWEAYYEEE 240
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
92-274 1.67e-07

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 51.61  E-value: 1.67e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  92 LVVTSQDGITTITLNRPDKKNALTTQMYHDIMLALEAAsKDDSAITVLTGNGDYYCSGNDltnFTDIPPG-GVEEKARSG 170
Cdd:PRK07112    6 IRVRQQGDVCFLQLHRPEAQNTINDRLIAECMDVLDRC-EHAATIVVLEGLPEVFCFGAD---FSAIAEKpDAGRADLID 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 171 AVLLRDFVDRFIDFPKPLVAVVNGPAVGISVTILGLFDIVYATDRATFHTPFSHLGQSPEGCSSYTFPKImGPSKATEML 250
Cdd:PRK07112   82 AEPLYDLWHRLATGPYVTIAHVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIPACVLPFLIRRI-GTQKAHYMT 160
                         170       180
                  ....*....|....*....|....
gi 1246192453 251 VFGKKLTAREACTQGLVTEVFPDS 274
Cdd:PRK07112  161 LMTQPVTAQQAFSWGLVDAYGANS 184
PTZ00458 PTZ00458
acyl CoA binding protein; Provisional
9-65 9.52e-07

acyl CoA binding protein; Provisional


Pssm-ID: 185637  Cd Length: 90  Bit Score: 46.35  E-value: 9.52e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1246192453   9 NEAKKERKGWMKQATEGPCNVPKPGVLDFINKAKWDAWNALGSLPKETARHNYVDLV 65
Cdd:PTZ00458   23 VEIKLDLYKYYKQSTVGNCNIKEPSMFKYQDRKKYEAWKSIENLNREDAKKRYVEIV 79
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
84-270 2.14e-04

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 43.29  E-value: 2.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453  84 RKQPGSDALVVTS------QDGITTITLNRPDKK-NALTTQMYHDIMLALEAASKDDS--AITVLTGNGDYYCSGNDLTN 154
Cdd:TIGR02441   1 RLFSTSAALMARThrhyevKGDVAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAikSAVLISGKPGSFVAGADIQM 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246192453 155 ftdIPPGGVEEKARSGAVLLRDFVDRFIDFPKPLVAVVNGPAVG--ISVTILGLFDIVYATDRATFHTPFSHLGQSPEGC 232
Cdd:TIGR02441  81 ---IAACKTAQEVTQLSQEGQEMFERIEKSQKPIVAAISGSCLGggLELALACHYRIATKDRKTLLGLPEVMLGLLPGAG 157
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1246192453 233 SSYTFPKIMGPSKATEMLVFGKKLTAREACTQGLVTEV 270
Cdd:TIGR02441 158 GTQRLPKLTGVPAALDMMLTGKKIRADRAKKMGIVDQL 195
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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