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Conserved domains on  [gi|1246220741|ref|XP_022407147|]
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glutathione hydrolase 5 proenzyme isoform X1 [Delphinapterus leucas]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
G_glu_transpept pfam01019
Gamma-glutamyltranspeptidase;
58-524 1.80e-174

Gamma-glutamyltranspeptidase;


:

Pssm-ID: 425991  Cd Length: 499  Bit Score: 508.29  E-value: 1.80e-174
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741  58 RAILQQHGSPVDATIAALVCTGVVNPQSMGLGGGVIFTIYNASTGKVEVINARETVPASHVPGLLDQCKQAQPLGTGAQW 137
Cdd:pfam01019   1 LDILRKGGNAVDAAVAAALCLGVVEPHSSGIGGGGFMLIYDAKTGKVLVIDARETAPAAATKDMFDGKGDSKLSLTGGLA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 138 IGVPGELRGYAEAHHRHGRLPWAQLFRPTIALLRGGLRVPRILSRFLRSSYLRPsLHASSLRQLFFNGTEPLSPHDPLPW 217
Cdd:pfam01019  81 VGVPGEVAGLAEAHKRYGRLPWADLLEPAIKLARDGFPVSPALARALARAEERL-RADPGLRKIFLPTGRVLKAGELLKQ 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 218 PALAATLETVAAEGAEALYTGRLGQMLLEDVAKEGSRLTPQDLASFRPEVVDALEVPLGDYTLYSPPPPAGGAILSFVLN 297
Cdd:pfam01019 160 PALAKTLELIAEEGPDAFYRGELAQQLVADLQANGGIITAEDLANYRVKIREPLSADYGGYTVYSPPPSSGGIALLQILN 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 298 VLKGFNFSAESvarpeGRVNLYHHLVETLKFARGQRWR-LWDPRSHPEVQnasQDLLGEALAQHIHQQIDTRGDHQLSHy 376
Cdd:pfam01019 240 ILEGFDLSSLL-----NSAEYLHLLIEAMKLAYADRTRyLGDPDFVPVPV---ENLLSPEYAKERAKLINPNAAFPSSY- 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 377 slaetWSHRMGTAHVSVLGEDGSAVSATSTINTPFGAMVYSPRTGILLNNELLDLCWRHRRGSGVTPPPVPGER----PP 452
Cdd:pfam01019 311 -----APEDGGTTHFSVVDRDGNAVSFTSTINLGFGSGVVVPGTGILLNNEMDDFSTPPGNAFGLDPSPANAIApgkrPL 385
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1246220741 453 SSMVPSILVNaAQGSKLVIGGAGGELIISAVAQAIMNKLWLGLDLQAAIAAPILHVDSKGRVEYEPSFSQDL 524
Cdd:pfam01019 386 SSMAPTIVLD-DGKPVLVVGAPGGSRIISAVLQVIVNVLDLGLDLQQAVDAPRIHHQLPDVLEVEPGFPEEV 456
Pro-rich_19 super family cl25804
Proline-rich 19; This family includes proline-rich protein 19.
555-683 4.79e-04

Proline-rich 19; This family includes proline-rich protein 19.


The actual alignment was detected with superfamily member pfam15455:

Pssm-ID: 464727  Cd Length: 363  Bit Score: 42.93  E-value: 4.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 555 PVPGPEPdreaRFPER---------GPGRVPGRGLRVRRSGPQEgwgafrlLKRLLPPQSWDPTQHTSRLAWSGRIWTPW 625
Cdd:pfam15455 204 PLPGTKP----GDPERqrmtpswinSPEQAPGEGRQRRRQGTKE-------LTFTMPHTSSTPTTHRVSLAPPRGPWPPP 272
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1246220741 626 LDGQPGASrggdspaeGRLWGPS-----------PALPEPLWPC--------PDPSN--LPRPLTQDCAPAPRSPIPHL 683
Cdd:pfam15455 273 LPSLSSPS--------GAAWGPPtafdllksiwlVATPPPPRPWgvgppqplPQPPSplLPRTSALDWSPSPPAPLPSL 343
 
Name Accession Description Interval E-value
G_glu_transpept pfam01019
Gamma-glutamyltranspeptidase;
58-524 1.80e-174

Gamma-glutamyltranspeptidase;


Pssm-ID: 425991  Cd Length: 499  Bit Score: 508.29  E-value: 1.80e-174
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741  58 RAILQQHGSPVDATIAALVCTGVVNPQSMGLGGGVIFTIYNASTGKVEVINARETVPASHVPGLLDQCKQAQPLGTGAQW 137
Cdd:pfam01019   1 LDILRKGGNAVDAAVAAALCLGVVEPHSSGIGGGGFMLIYDAKTGKVLVIDARETAPAAATKDMFDGKGDSKLSLTGGLA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 138 IGVPGELRGYAEAHHRHGRLPWAQLFRPTIALLRGGLRVPRILSRFLRSSYLRPsLHASSLRQLFFNGTEPLSPHDPLPW 217
Cdd:pfam01019  81 VGVPGEVAGLAEAHKRYGRLPWADLLEPAIKLARDGFPVSPALARALARAEERL-RADPGLRKIFLPTGRVLKAGELLKQ 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 218 PALAATLETVAAEGAEALYTGRLGQMLLEDVAKEGSRLTPQDLASFRPEVVDALEVPLGDYTLYSPPPPAGGAILSFVLN 297
Cdd:pfam01019 160 PALAKTLELIAEEGPDAFYRGELAQQLVADLQANGGIITAEDLANYRVKIREPLSADYGGYTVYSPPPSSGGIALLQILN 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 298 VLKGFNFSAESvarpeGRVNLYHHLVETLKFARGQRWR-LWDPRSHPEVQnasQDLLGEALAQHIHQQIDTRGDHQLSHy 376
Cdd:pfam01019 240 ILEGFDLSSLL-----NSAEYLHLLIEAMKLAYADRTRyLGDPDFVPVPV---ENLLSPEYAKERAKLINPNAAFPSSY- 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 377 slaetWSHRMGTAHVSVLGEDGSAVSATSTINTPFGAMVYSPRTGILLNNELLDLCWRHRRGSGVTPPPVPGER----PP 452
Cdd:pfam01019 311 -----APEDGGTTHFSVVDRDGNAVSFTSTINLGFGSGVVVPGTGILLNNEMDDFSTPPGNAFGLDPSPANAIApgkrPL 385
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1246220741 453 SSMVPSILVNaAQGSKLVIGGAGGELIISAVAQAIMNKLWLGLDLQAAIAAPILHVDSKGRVEYEPSFSQDL 524
Cdd:pfam01019 386 SSMAPTIVLD-DGKPVLVVGAPGGSRIISAVLQVIVNVLDLGLDLQQAVDAPRIHHQLPDVLEVEPGFPEEV 456
Ggt COG0405
Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
54-524 1.71e-94

Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];


Pssm-ID: 440174  Cd Length: 507  Bit Score: 302.36  E-value: 1.71e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741  54 SDIGRAILQQHGSPVDATIAALVCTGVVNPQSMGLGGGVIFTIYNASTGKVEVINARETVPASHVPGLLDQCKQAQPlGT 133
Cdd:COG0405    10 SQAGLEILRAGGNAVDAAVAAAAALAVVEPHSSGIGGGGFALIYDAKDGKVTALDGRGTAPAAATPDMYLDAGDEIP-VR 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 134 GAQWIGVPGELRGYAEAHHRHGRLPWAQLFRPTIALLRGGLRVPRILSRFLRSSYLRPSLHASSlRQLFFNGTEPLSPHD 213
Cdd:COG0405    89 GPLAVGVPGTVAGWEAAHERYGTLPLAELLAPAIRLAEDGFPVSPRLAALLAAAAERLARDPGA-AAIFLPDGRPPKAGD 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 214 PLPWPALAATLETVAAEGAEALYTGRLGQMLLEDVAKEGSRLTPQDLASFRPEVVDALEVPLGDYTLYSPPPPAGGAILS 293
Cdd:COG0405   168 ILRQPDLAATLRRIAEEGADAFYRGEIAEAIVAAVQAAGGLLTLEDLAAYRAEWREPLSGTYRGYTVYSMPPPSQGIALL 247
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 294 FVLNVLKGFNFSAESVARPEGrvnlYHHLVETLK--FARGQRWrLWDPRShpeVQNASQDLLGEALAQHIHQQID-TRGD 370
Cdd:COG0405   248 QILNILEGFDLAALGPDSAEY----VHLLAEAMKlaFADRDRY-LGDPDF---VDVPVEGLLSPAYAAERAALIDpDRAT 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 371 HQLSHYSLAETWSHrmGTAHVSVLGEDGSAVSATSTINTPFGAMVYSPRTGILLNNELLD--------LCW----RHRrg 438
Cdd:COG0405   320 PSPRPGDPTGPESG--DTTHLSVVDRDGNAVSLTQSIYGGFGSGVVVPGTGFLLNNRGDDfsldpghpNALapgkRPR-- 395
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 439 sgvtpppvpgerppSSMVPSILVnaaQGSK--LVIGGAGGELIISAVAQAIMNKLWLGLDLQAAIAAP-ILHVDSKGRVE 515
Cdd:COG0405   396 --------------STMSPTIVL---KDGKpvLVFGSPGGSRIPQTVLQVLLNVLDFGMNPQEAVDAPrWHHQGLPDTLE 458

                  ....*....
gi 1246220741 516 YEPSFSQDL 524
Cdd:COG0405   459 LEPRFPPAV 467
g_glut_trans TIGR00066
gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of ...
54-524 8.63e-78

gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of this family have antibiotic synthesis or resistance activities. In the case of a cephalosporin acylase from Pseudomonas sp., the enzyme was shown to retain some gamma-glutamyltranspeptidase activity. Other, more distantly related proteins have ggt-related activities and score below the trusted cutoff. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]


Pssm-ID: 129176  Cd Length: 516  Bit Score: 258.54  E-value: 8.63e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741  54 SDIGRAILQQHGSPVDATIAALVCTGVVNPQSMGLGGGVIFTIYNASTGKVEVINARETVPAShVPGLLDQCKQAQPL-- 131
Cdd:TIGR00066  11 SEIGEDILKEGGNAFDAAVAVGLALAVVEPFMTGLGGGGFMLISGKKTKDTTAIDFRERAPAK-ATRDMFLDKSGNPLpg 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 132 --GTGAQWIGVPGELRGYAEAHHRHGRLPWAQLFRPTIALLRGGLRVPRILSRFLrSSYLRPSL-HASSLRQLFFNGTEP 208
Cdd:TIGR00066  90 ksLTGGLAIGVPGTVAGLEAALKKYGTLPLKDLIEPAIKLARNGFPINEALADTL-ELYEEVLLtTKEDSKDIFNPTGKP 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 209 LSPHDPLPWPALAATLETVAAEGAEALYTGRLGQMLLEDVAKEGSRLTPQDLASFRPEVvdalEVPL-GDYTLYS----P 283
Cdd:TIGR00066 169 LKEGDTLVQKDLAKSLELIAENGPDAFYKGDIAESIIDTLQKNGGIMTKKDLAAYDVEI----RKPLsGDYRGYQvyttP 244
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 284 PPPAGGAILSFVLNVLKGFNFSAesvaRPEGRVNLYHHLVETLKFARGQRWR-LWDPRShpeVQNASQDLLGEALAQHIH 362
Cdd:TIGR00066 245 PPSSGGIHLLQALNILENFDLSQ----YGDGSAETYQLLAEAMKLSYADRSRyLGDPEF---VDVPLEELLDKRYAKELA 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 363 QQIDTRGDHQLSHYSLAETWSHR-MGTAHVSVLGEDGSAVSATSTINTPFGAMVYSPRTGILLNNELLDLCWRhrrgSGV 441
Cdd:TIGR00066 318 QSIKINKVDPKSTIYPGAYQPNEgSQTTHFSVVDRDGNAVSLTTTINLEFGSGVHAPDTGILLNNEMDDFSLK----PGG 393
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 442 TPPPVPGERPPSSMVPSILVNAAQgSKLVIGGAGGELIISAVAQAIMNKLWLGLDLQAAIAAPILHVDS-KGRVEYEPSF 520
Cdd:TIGR00066 394 ANAVEPNKRPLSSMAPTIVLKDGK-PDLVVGSPGGSRIITTVLQTIVRHIDYGMPLAEAVSEPRIHHQWlPDELRLEKGF 472

                  ....
gi 1246220741 521 SQDL 524
Cdd:TIGR00066 473 PDDV 476
PLN02198 PLN02198
glutathione gamma-glutamylcysteinyltransferase
49-517 6.32e-67

glutathione gamma-glutamylcysteinyltransferase


Pssm-ID: 177849  Cd Length: 573  Bit Score: 231.12  E-value: 6.32e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741  49 DSKICSDIGRAILQQHGSPVDATIAALVCTGVVNPQSMGLGGGViFTIYNASTGKVEVINARETVPASHVPGLLDQckQA 128
Cdd:PLN02198   39 DDGRCSVIGMNVLREGGNAIDASVAAALCLGVVSPASSGIGGGA-FTLIKLANGEEIAYDSRETAPLSATENMYGG--NV 115
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 129 QPLGTGAQWIGVPGELRGYAEAHHRHGRLPWAQLFRPTIALLRGGLRVPRILSRFLRSSYlRPSLHASSLRQLFFNGTEP 208
Cdd:PLN02198  116 ELKKKGALSVGVPGEVAGLFTAWKQHGKLPWKRLVRPAEKLAAEGFKISKYLYMQMNATR-SDILADKGLSDLFVSNGEL 194
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 209 LSPHDPLPWPALAATLETVAAEGAEALYTGRLGQMLLEDVAKEGSRLTPQDLASFRPEVVDALEVP-LGDYTLYSPPPPA 287
Cdd:PLN02198  195 KKPGTICHNPKLALTLRLIGEYGPKAFYNGTVGVNLVRDIQKSGGIITLKDLQSYRVKVKEPLSADiLGYRVLGMPPPSS 274
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 288 GGAILSFVLNVLKGFNFSAeSVARPEGrvnlYHHLVETLKFARGQRWRLWDPrSHPEVQNASQDLLGEALAQHIHQQIDT 367
Cdd:PLN02198  275 GGAAMMLILNILAQYGIPS-GVSGPLG----VHRLIEALKHAFAVRMNLGDP-DFVDVTKVVSDMLSPKFAQDLKSKIND 348
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 368 RGDHQLSHYSLAETWSHRMGTAHVSVLGEDGSAVSATSTINTPFGAMVYSPRTGILLNNELLDLCWRHRRGSGVTPPPVP 447
Cdd:PLN02198  349 NKTFDPKHYGGRWNQIDDHGTSHLSIIDSERNAVSMTSTINGYFGALMLSPSTGIVLNNEMDDFSIPMKSGGNLDVPPPA 428
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1246220741 448 GERP-------PSSMVPSILVNAAQgSKLVIGGAGGELIISAVAQAIMNKLWLGLDLQAAIAAP-ILHVDSKGRVEYE 517
Cdd:PLN02198  429 PANFirpgkrpLSSMTPTIVLKDGK-VKAAVGASGGANIIAGTTEVYLNHFFLKMDPLSSVLAPrIYHQLIPNRASYE 505
Pro-rich_19 pfam15455
Proline-rich 19; This family includes proline-rich protein 19.
555-683 4.79e-04

Proline-rich 19; This family includes proline-rich protein 19.


Pssm-ID: 464727  Cd Length: 363  Bit Score: 42.93  E-value: 4.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 555 PVPGPEPdreaRFPER---------GPGRVPGRGLRVRRSGPQEgwgafrlLKRLLPPQSWDPTQHTSRLAWSGRIWTPW 625
Cdd:pfam15455 204 PLPGTKP----GDPERqrmtpswinSPEQAPGEGRQRRRQGTKE-------LTFTMPHTSSTPTTHRVSLAPPRGPWPPP 272
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1246220741 626 LDGQPGASrggdspaeGRLWGPS-----------PALPEPLWPC--------PDPSN--LPRPLTQDCAPAPRSPIPHL 683
Cdd:pfam15455 273 LPSLSSPS--------GAAWGPPtafdllksiwlVATPPPPRPWgvgppqplPQPPSplLPRTSALDWSPSPPAPLPSL 343
PHA03247 PHA03247
large tegument protein UL36; Provisional
530-679 1.37e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 1.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741  530 DLTAWNPENPEPTALSSLEGGEEGAPVPGPEPDREARFPERG--PGRVPGRGLRVRRSGPQEGWgafrlLKRLLPP---- 603
Cdd:PHA03247  2620 DTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVsrPRRARRLGRAAQASSPPQRP-----RRRAARPtvgs 2694
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1246220741  604 --QSWDPTQHTSRLAWSGRIWTPWLDGQPG-ASRGGDSPAEGRLWGPSPALPEPLWPCpDPSNLPRPLTQDCAPAPRSP 679
Cdd:PHA03247  2695 ltSLADPPPPPPTPEPAPHALVSATPLPPGpAAARQASPALPAAPAPPAVPAGPATPG-GPARPARPPTTAGPPAPAPP 2772
 
Name Accession Description Interval E-value
G_glu_transpept pfam01019
Gamma-glutamyltranspeptidase;
58-524 1.80e-174

Gamma-glutamyltranspeptidase;


Pssm-ID: 425991  Cd Length: 499  Bit Score: 508.29  E-value: 1.80e-174
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741  58 RAILQQHGSPVDATIAALVCTGVVNPQSMGLGGGVIFTIYNASTGKVEVINARETVPASHVPGLLDQCKQAQPLGTGAQW 137
Cdd:pfam01019   1 LDILRKGGNAVDAAVAAALCLGVVEPHSSGIGGGGFMLIYDAKTGKVLVIDARETAPAAATKDMFDGKGDSKLSLTGGLA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 138 IGVPGELRGYAEAHHRHGRLPWAQLFRPTIALLRGGLRVPRILSRFLRSSYLRPsLHASSLRQLFFNGTEPLSPHDPLPW 217
Cdd:pfam01019  81 VGVPGEVAGLAEAHKRYGRLPWADLLEPAIKLARDGFPVSPALARALARAEERL-RADPGLRKIFLPTGRVLKAGELLKQ 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 218 PALAATLETVAAEGAEALYTGRLGQMLLEDVAKEGSRLTPQDLASFRPEVVDALEVPLGDYTLYSPPPPAGGAILSFVLN 297
Cdd:pfam01019 160 PALAKTLELIAEEGPDAFYRGELAQQLVADLQANGGIITAEDLANYRVKIREPLSADYGGYTVYSPPPSSGGIALLQILN 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 298 VLKGFNFSAESvarpeGRVNLYHHLVETLKFARGQRWR-LWDPRSHPEVQnasQDLLGEALAQHIHQQIDTRGDHQLSHy 376
Cdd:pfam01019 240 ILEGFDLSSLL-----NSAEYLHLLIEAMKLAYADRTRyLGDPDFVPVPV---ENLLSPEYAKERAKLINPNAAFPSSY- 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 377 slaetWSHRMGTAHVSVLGEDGSAVSATSTINTPFGAMVYSPRTGILLNNELLDLCWRHRRGSGVTPPPVPGER----PP 452
Cdd:pfam01019 311 -----APEDGGTTHFSVVDRDGNAVSFTSTINLGFGSGVVVPGTGILLNNEMDDFSTPPGNAFGLDPSPANAIApgkrPL 385
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1246220741 453 SSMVPSILVNaAQGSKLVIGGAGGELIISAVAQAIMNKLWLGLDLQAAIAAPILHVDSKGRVEYEPSFSQDL 524
Cdd:pfam01019 386 SSMAPTIVLD-DGKPVLVVGAPGGSRIISAVLQVIVNVLDLGLDLQQAVDAPRIHHQLPDVLEVEPGFPEEV 456
Ggt COG0405
Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
54-524 1.71e-94

Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];


Pssm-ID: 440174  Cd Length: 507  Bit Score: 302.36  E-value: 1.71e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741  54 SDIGRAILQQHGSPVDATIAALVCTGVVNPQSMGLGGGVIFTIYNASTGKVEVINARETVPASHVPGLLDQCKQAQPlGT 133
Cdd:COG0405    10 SQAGLEILRAGGNAVDAAVAAAAALAVVEPHSSGIGGGGFALIYDAKDGKVTALDGRGTAPAAATPDMYLDAGDEIP-VR 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 134 GAQWIGVPGELRGYAEAHHRHGRLPWAQLFRPTIALLRGGLRVPRILSRFLRSSYLRPSLHASSlRQLFFNGTEPLSPHD 213
Cdd:COG0405    89 GPLAVGVPGTVAGWEAAHERYGTLPLAELLAPAIRLAEDGFPVSPRLAALLAAAAERLARDPGA-AAIFLPDGRPPKAGD 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 214 PLPWPALAATLETVAAEGAEALYTGRLGQMLLEDVAKEGSRLTPQDLASFRPEVVDALEVPLGDYTLYSPPPPAGGAILS 293
Cdd:COG0405   168 ILRQPDLAATLRRIAEEGADAFYRGEIAEAIVAAVQAAGGLLTLEDLAAYRAEWREPLSGTYRGYTVYSMPPPSQGIALL 247
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 294 FVLNVLKGFNFSAESVARPEGrvnlYHHLVETLK--FARGQRWrLWDPRShpeVQNASQDLLGEALAQHIHQQID-TRGD 370
Cdd:COG0405   248 QILNILEGFDLAALGPDSAEY----VHLLAEAMKlaFADRDRY-LGDPDF---VDVPVEGLLSPAYAAERAALIDpDRAT 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 371 HQLSHYSLAETWSHrmGTAHVSVLGEDGSAVSATSTINTPFGAMVYSPRTGILLNNELLD--------LCW----RHRrg 438
Cdd:COG0405   320 PSPRPGDPTGPESG--DTTHLSVVDRDGNAVSLTQSIYGGFGSGVVVPGTGFLLNNRGDDfsldpghpNALapgkRPR-- 395
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 439 sgvtpppvpgerppSSMVPSILVnaaQGSK--LVIGGAGGELIISAVAQAIMNKLWLGLDLQAAIAAP-ILHVDSKGRVE 515
Cdd:COG0405   396 --------------STMSPTIVL---KDGKpvLVFGSPGGSRIPQTVLQVLLNVLDFGMNPQEAVDAPrWHHQGLPDTLE 458

                  ....*....
gi 1246220741 516 YEPSFSQDL 524
Cdd:COG0405   459 LEPRFPPAV 467
g_glut_trans TIGR00066
gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of ...
54-524 8.63e-78

gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of this family have antibiotic synthesis or resistance activities. In the case of a cephalosporin acylase from Pseudomonas sp., the enzyme was shown to retain some gamma-glutamyltranspeptidase activity. Other, more distantly related proteins have ggt-related activities and score below the trusted cutoff. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]


Pssm-ID: 129176  Cd Length: 516  Bit Score: 258.54  E-value: 8.63e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741  54 SDIGRAILQQHGSPVDATIAALVCTGVVNPQSMGLGGGVIFTIYNASTGKVEVINARETVPAShVPGLLDQCKQAQPL-- 131
Cdd:TIGR00066  11 SEIGEDILKEGGNAFDAAVAVGLALAVVEPFMTGLGGGGFMLISGKKTKDTTAIDFRERAPAK-ATRDMFLDKSGNPLpg 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 132 --GTGAQWIGVPGELRGYAEAHHRHGRLPWAQLFRPTIALLRGGLRVPRILSRFLrSSYLRPSL-HASSLRQLFFNGTEP 208
Cdd:TIGR00066  90 ksLTGGLAIGVPGTVAGLEAALKKYGTLPLKDLIEPAIKLARNGFPINEALADTL-ELYEEVLLtTKEDSKDIFNPTGKP 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 209 LSPHDPLPWPALAATLETVAAEGAEALYTGRLGQMLLEDVAKEGSRLTPQDLASFRPEVvdalEVPL-GDYTLYS----P 283
Cdd:TIGR00066 169 LKEGDTLVQKDLAKSLELIAENGPDAFYKGDIAESIIDTLQKNGGIMTKKDLAAYDVEI----RKPLsGDYRGYQvyttP 244
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 284 PPPAGGAILSFVLNVLKGFNFSAesvaRPEGRVNLYHHLVETLKFARGQRWR-LWDPRShpeVQNASQDLLGEALAQHIH 362
Cdd:TIGR00066 245 PPSSGGIHLLQALNILENFDLSQ----YGDGSAETYQLLAEAMKLSYADRSRyLGDPEF---VDVPLEELLDKRYAKELA 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 363 QQIDTRGDHQLSHYSLAETWSHR-MGTAHVSVLGEDGSAVSATSTINTPFGAMVYSPRTGILLNNELLDLCWRhrrgSGV 441
Cdd:TIGR00066 318 QSIKINKVDPKSTIYPGAYQPNEgSQTTHFSVVDRDGNAVSLTTTINLEFGSGVHAPDTGILLNNEMDDFSLK----PGG 393
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 442 TPPPVPGERPPSSMVPSILVNAAQgSKLVIGGAGGELIISAVAQAIMNKLWLGLDLQAAIAAPILHVDS-KGRVEYEPSF 520
Cdd:TIGR00066 394 ANAVEPNKRPLSSMAPTIVLKDGK-PDLVVGSPGGSRIITTVLQTIVRHIDYGMPLAEAVSEPRIHHQWlPDELRLEKGF 472

                  ....
gi 1246220741 521 SQDL 524
Cdd:TIGR00066 473 PDDV 476
PLN02198 PLN02198
glutathione gamma-glutamylcysteinyltransferase
49-517 6.32e-67

glutathione gamma-glutamylcysteinyltransferase


Pssm-ID: 177849  Cd Length: 573  Bit Score: 231.12  E-value: 6.32e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741  49 DSKICSDIGRAILQQHGSPVDATIAALVCTGVVNPQSMGLGGGViFTIYNASTGKVEVINARETVPASHVPGLLDQckQA 128
Cdd:PLN02198   39 DDGRCSVIGMNVLREGGNAIDASVAAALCLGVVSPASSGIGGGA-FTLIKLANGEEIAYDSRETAPLSATENMYGG--NV 115
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 129 QPLGTGAQWIGVPGELRGYAEAHHRHGRLPWAQLFRPTIALLRGGLRVPRILSRFLRSSYlRPSLHASSLRQLFFNGTEP 208
Cdd:PLN02198  116 ELKKKGALSVGVPGEVAGLFTAWKQHGKLPWKRLVRPAEKLAAEGFKISKYLYMQMNATR-SDILADKGLSDLFVSNGEL 194
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 209 LSPHDPLPWPALAATLETVAAEGAEALYTGRLGQMLLEDVAKEGSRLTPQDLASFRPEVVDALEVP-LGDYTLYSPPPPA 287
Cdd:PLN02198  195 KKPGTICHNPKLALTLRLIGEYGPKAFYNGTVGVNLVRDIQKSGGIITLKDLQSYRVKVKEPLSADiLGYRVLGMPPPSS 274
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 288 GGAILSFVLNVLKGFNFSAeSVARPEGrvnlYHHLVETLKFARGQRWRLWDPrSHPEVQNASQDLLGEALAQHIHQQIDT 367
Cdd:PLN02198  275 GGAAMMLILNILAQYGIPS-GVSGPLG----VHRLIEALKHAFAVRMNLGDP-DFVDVTKVVSDMLSPKFAQDLKSKIND 348
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 368 RGDHQLSHYSLAETWSHRMGTAHVSVLGEDGSAVSATSTINTPFGAMVYSPRTGILLNNELLDLCWRHRRGSGVTPPPVP 447
Cdd:PLN02198  349 NKTFDPKHYGGRWNQIDDHGTSHLSIIDSERNAVSMTSTINGYFGALMLSPSTGIVLNNEMDDFSIPMKSGGNLDVPPPA 428
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1246220741 448 GERP-------PSSMVPSILVNAAQgSKLVIGGAGGELIISAVAQAIMNKLWLGLDLQAAIAAP-ILHVDSKGRVEYE 517
Cdd:PLN02198  429 PANFirpgkrpLSSMTPTIVLKDGK-VKAAVGASGGANIIAGTTEVYLNHFFLKMDPLSSVLAPrIYHQLIPNRASYE 505
PLN02180 PLN02180
gamma-glutamyl transpeptidase 4
49-517 4.30e-66

gamma-glutamyl transpeptidase 4


Pssm-ID: 177836  Cd Length: 639  Bit Score: 230.34  E-value: 4.30e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741  49 DSKICSDIGRAILQQHGSPVDATIAALVCTGVVNPQSMGLGGGVIFTIYNASTGKVEVINARETVPASHVPGLLDQCKQA 128
Cdd:PLN02180   88 DDARCSEIGASVLRRGGHAVDAAVAITLCIGVVNPMSSGIGGGSFLIVSSQKDSKAEAFDMRETAPLAASKDMYKNDASA 167
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 129 QPLGtgAQWIGVPGELRGYAEAHHRHGRLPWAQLFRPTIALLRGGLRVPRILSRFLrSSYLRPSLHASSLRQLFFNGTEP 208
Cdd:PLN02180  168 KSLG--ALSMGVPGEIAGLYEAWKRYGRLPWKPLFEPAIELARDGFVVHPYLGKAI-SSHAAMILKDPGLRSVFSRNGQV 244
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 209 LSPHDPLPWPALAATLETVAAEGAEALYTGRLGQMLLEDVAKEGSRLTPQDLASFRPEVVDALEVPLGDYTLYSPPPPAG 288
Cdd:PLN02180  245 LKPGETCYNPELAQSLETISEQGPGAFYNGTIGEKLVKDVKKAGGIITMDDLRSYEVLVTDAMSVDVMGYTIHGMPPPSG 324
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 289 GAI-LSFVLNVLKGFNfsaeSVARPEGRVNLYHHLVETLKFARGQRWRLWDPrSHPEVQNASQDLLGEALAQHIHQQIDT 367
Cdd:PLN02180  325 GTLgFSMVIDILDSYS----NLYTASGRELGLHRLIEAMKHMFAARMDLGDP-EFVNITNAMNQMLSKAHAEEIQKRIFD 399
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 368 RGDHQLSHYslAETWSH--RMGTAHVSVLGEDGSAVSATSTINTPFGAMVYSPRTGILLNNELLDLC-----WRHRRGSG 440
Cdd:PLN02180  400 NTTFPPEYY--LNRWSQlrDQGTSHFCIVDADRNSVSMTSTVNYGFGAGVLSPSTGIVLNNEMDDFStpaeiTPDMLPPA 477
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1246220741 441 VTPPPVPGERPPSSMVPSILVNAAQGSKlVIGGAGGELIISAVAQAIMNKLWLGLDLQAAI-AAPILHVDSKGRVEYE 517
Cdd:PLN02180  478 PTNFIEPNKRPLSSMTPLVITKDGEFVA-ALGGAGGMHIIPAVLQVFLNCFVLNMKPKEAVeSARIYHRLIPNVVSYE 554
ggt PRK09615
gamma-glutamyltranspeptidase; Reviewed
56-507 4.72e-49

gamma-glutamyltranspeptidase; Reviewed


Pssm-ID: 181992  Cd Length: 581  Bit Score: 181.64  E-value: 4.72e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741  56 IGRAILQQHGSPVDATIAALVCTGVVNPQSMGLGGGViFTIYNASTGKVEVINARETVPASHVPGL-LDqcKQAQPLG-- 132
Cdd:PRK09615   62 VGVDILKQGGNAVDAAVAVGYALAVTHPQAGNLGGGG-FMLLRTKNGNTTAIDFREMAPAKATRDMfLD--DQGNPDSkk 138
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 133 --TGAQWIGVPGELRGYAEAHHRHGRLPWAQLFRPTIALLRGGLRVPRILSRFLRSsYLRPSL--HASSlRQLFFNGTEP 208
Cdd:PRK09615  139 slTSHLASGTPGTVAGFSLALDKYGTMPLNKVVQPAFKLARDGFIVNDALADDLKT-YGSEVLpnHENS-KAIFWKEGEP 216
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 209 LSPHDPLPWPALAATLETVAAEGAEALYTGRLGQMLLEDVAKEGSRLTPQDLASFRpevvdALE-VPLGD----YTLYSP 283
Cdd:PRK09615  217 LKKGDKLVQANLAKSLEMIAENGPDAFYKGTIADQIAQEMQKNGGLITKEDLAAYK-----AVErTPISGdyrgYQVYSM 291
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 284 PPPAGGAI-LSFVLNVLKGFNFSAESVarpeGRVNLYHHLVETLKFARGQRWR-LWDPRShpeVQNASQDLLGEALAQHI 361
Cdd:PRK09615  292 PPPSSGGIhIVQILNILENFDMKKYGF----GSADAMQIMAEAEKYAYADRSEyLGDPDF---VKVPWQALTNKAYAKSI 364
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 362 HQQID---TRGDHQLSHYSLAETWSHRmgTAHVSVLGEDGSAVSATSTINTPFGAMVYSPRTGILLNNELLDLCWR---- 434
Cdd:PRK09615  365 ADQIDinkAKPSSEIRPGKLAPYESNQ--TTHFSVVDKDGNAVAVTYTLNTTFGTGIVAGNSGILLNNQMDDFSAKpgvp 442
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1246220741 435 --HRRGSGVTPPPVPGERPPSSMVPSILVNAAQgSKLVIGGAGGELIISAVAQAIMNKLWLGLDLQAAIAAPILH 507
Cdd:PRK09615  443 nvYGLVGGDANAVGPNKRPLSSMSPTIVVKDGK-TWLVTGSPGGSRIITTVLQMVVNSIDYGMNVAEATNAPRFH 516
Pro-rich_19 pfam15455
Proline-rich 19; This family includes proline-rich protein 19.
555-683 4.79e-04

Proline-rich 19; This family includes proline-rich protein 19.


Pssm-ID: 464727  Cd Length: 363  Bit Score: 42.93  E-value: 4.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741 555 PVPGPEPdreaRFPER---------GPGRVPGRGLRVRRSGPQEgwgafrlLKRLLPPQSWDPTQHTSRLAWSGRIWTPW 625
Cdd:pfam15455 204 PLPGTKP----GDPERqrmtpswinSPEQAPGEGRQRRRQGTKE-------LTFTMPHTSSTPTTHRVSLAPPRGPWPPP 272
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1246220741 626 LDGQPGASrggdspaeGRLWGPS-----------PALPEPLWPC--------PDPSN--LPRPLTQDCAPAPRSPIPHL 683
Cdd:pfam15455 273 LPSLSSPS--------GAAWGPPtafdllksiwlVATPPPPRPWgvgppqplPQPPSplLPRTSALDWSPSPPAPLPSL 343
PHA03247 PHA03247
large tegument protein UL36; Provisional
530-679 1.37e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 1.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1246220741  530 DLTAWNPENPEPTALSSLEGGEEGAPVPGPEPDREARFPERG--PGRVPGRGLRVRRSGPQEGWgafrlLKRLLPP---- 603
Cdd:PHA03247  2620 DTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVsrPRRARRLGRAAQASSPPQRP-----RRRAARPtvgs 2694
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1246220741  604 --QSWDPTQHTSRLAWSGRIWTPWLDGQPG-ASRGGDSPAEGRLWGPSPALPEPLWPCpDPSNLPRPLTQDCAPAPRSP 679
Cdd:PHA03247  2695 ltSLADPPPPPPTPEPAPHALVSATPLPPGpAAARQASPALPAAPAPPAVPAGPATPG-GPARPARPPTTAGPPAPAPP 2772
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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