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Conserved domains on  [gi|1210014975|ref|XP_021401783|]
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6-phosphogluconolactonase [Lonchura striata domestica]

Protein Classification

6-phosphogluconolactonase( domain architecture ID 10471859)

6-phosphogluconolactonase catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate, which is the the second step of the oxidative phase of the pentose phosphate pathway

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glucosamine_iso pfam01182
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
8-234 6.79e-74

Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;


:

Pssm-ID: 460101 [Multi-domain]  Cd Length: 222  Bit Score: 224.42  E-value: 6.79e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975   8 PSPAELGAALARSVAEAAAEAVASGGRFTLGLSGGSLVALLARELPAALRAAPgaePSRWLLAFCDERLVPPEHPDSTGG 87
Cdd:pfam01182   1 PDAEALAQALAERLAEALEAALAERGRFTLALSGGSTPKPLYELLAAAPARLD---WSRVHVFWGDERCVPPDDPDSNYG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975  88 AYRSQLLSQFAPPGPRVLWV-SSGLGPAEAARDYEEQLRREFPGEATPRFDLLLLGVGPDGHTCSLFPGHALLQEQNSLI 166
Cdd:pfam01182  78 MAREALLSHVPIPASNVHPIpASAADPEEAAAAYEAELRELLPDLELPVFDLVLLGMGPDGHTASLFPGSPALEETDRLV 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1210014975 167 SFLEDSPKPPPRRVTMTLPLLNAARALLVVATGASKAPVIKRILEeprEEAPSLPAARLRPRSGRLRW 234
Cdd:pfam01182 158 VAVTDSPKPPPERITLTLPVLNAARRVWFLVTGAGKADALRRALA---GDPDPLPAALVRPGAGETVW 222
 
Name Accession Description Interval E-value
Glucosamine_iso pfam01182
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
8-234 6.79e-74

Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;


Pssm-ID: 460101 [Multi-domain]  Cd Length: 222  Bit Score: 224.42  E-value: 6.79e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975   8 PSPAELGAALARSVAEAAAEAVASGGRFTLGLSGGSLVALLARELPAALRAAPgaePSRWLLAFCDERLVPPEHPDSTGG 87
Cdd:pfam01182   1 PDAEALAQALAERLAEALEAALAERGRFTLALSGGSTPKPLYELLAAAPARLD---WSRVHVFWGDERCVPPDDPDSNYG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975  88 AYRSQLLSQFAPPGPRVLWV-SSGLGPAEAARDYEEQLRREFPGEATPRFDLLLLGVGPDGHTCSLFPGHALLQEQNSLI 166
Cdd:pfam01182  78 MAREALLSHVPIPASNVHPIpASAADPEEAAAAYEAELRELLPDLELPVFDLVLLGMGPDGHTASLFPGSPALEETDRLV 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1210014975 167 SFLEDSPKPPPRRVTMTLPLLNAARALLVVATGASKAPVIKRILEeprEEAPSLPAARLRPRSGRLRW 234
Cdd:pfam01182 158 VAVTDSPKPPPERITLTLPVLNAARRVWFLVTGAGKADALRRALA---GDPDPLPAALVRPGAGETVW 222
6PGL cd01400
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the ...
 34-236 1.36e-72

6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the accumulation of the delta form of the lactone, which may be toxic through its reaction with endogenous cellular nucleophiles.


Pssm-ID: 238694 [Multi-domain]  Cd Length: 219  Bit Score: 220.90  E-value: 1.36e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975  34 RFTLGLSGGSLVALLARelpaALRAAPGAEPSRWLLAFCDERLVPPEHPDSTGGAYRSQLLSQFAPPGPRVLWVSSGLGP 113
Cdd:cd01400    24 RFSLALSGGSTPKPLYE----LLAAAPALDWSKVHVFLGDERCVPPDDPDSNYRLAREALLSHVAIPAANIHPIPTELGP 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975 114 AEAARDYEEQLRREFPGeaTPRFDLLLLGVGPDGHTCSLFPGH-ALLQEQNSLISFLEDSPKPPPRRVTMTLPLLNAARA 192
Cdd:cd01400   100 EDAAAAYEKELRALFGG--VPPFDLVLLGMGPDGHTASLFPGHpALLEETDRLVVAVTDSPKPPPERITLTLPVLNNARR 177

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1210014975 193 LLVVATGASKAPVIKRILEEPreEAPSLPAARLRPRSGRLRWLL 236
Cdd:cd01400   178 VVFLVTGAEKAEALKRALAGP--DPEELPAARVLPRPGEVLWFL 219
pgl TIGR01198
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a ...
 6-244 1.94e-60

6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a part of a multifunctional protein with [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273494 [Multi-domain]  Cd Length: 233  Bit Score: 190.28  E-value: 1.94e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975   6 VFPSPAELGAALARSVAEAAAEAVASGGRFTLGLSGGSLVALLARELPAAlraapGAEPSRWLLAFCDERLVPPEHPDST 85
Cdd:TIGR01198   1 VFSNSAELAEALAERIATKLQTALAERGQFSLALSGGRSPIALLEALAAQ-----PLDWSRIHLFLGDERYVPLDHADSN 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975  86 GGAYRSQLLSQFAPPGPRVLWVSSGLG-PAEAARDYEEQLRREFPGEATPRFDLLLLGVGPDGHTCSLFPGHALLQEQNS 164
Cdd:TIGR01198  76 TGLAREALLDRVAIPASNIHPMPTELSdIEEAAELYEQELAAAFQPIVFPVFDLLLLGMGPDGHTASLFPHTPALQETER 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975 165 LISFLEDSPKPPPRRVTMTLPLLNAARALLVVATGASKAPVIKRILEEprEEAPSLPAARLRPRSGRLRWLLDREAAEEL 244
Cdd:TIGR01198 156 LVTVLTKSPKPPHERITLTLPAINAARKVFLLIAGEEKRNALAEALAV--EAEPYPLPAAGVLHSGKTLWLLDYAAARKL 233
NagB COG0363
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport ...
 4-244 4.39e-53

6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440132 [Multi-domain]  Cd Length: 248  Bit Score: 171.88  E-value: 4.39e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975   4 VSVFPSPAELGAALARSVAEAAAEAVASGGRFTLGLSGGSLVALLARELpAALRAAPGAEPSRWLLAFCDERL-VPPEHP 82
Cdd:COG0363     4 VIIFPDAEELAAAAAERAAERIAEAIAEKGRAVLGLAGGSTPLGLYEEL-ARLHKEGGLDWSRVHVFNLDEYVgLPPDHP 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975  83 DSTGGAYRSQLLSQFAPPGPRV-LWVSSGLGPAEAARDYEEQLRrefpgeATPRFDLLLLGVGPDGHTCSLFPGHALLQE 161
Cdd:COG0363    83 QSNRRFMREALLDHVDIPPENIhIPDGEAEDPEAAAARYEALIA------EAGGIDLQLLGIGEDGHIAFNFPGSPFLSE 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975 162 QNSLI-----------SFLEDSPKPPPRRVTMTLPLLNAARALLVVATGASKAPVIKRILEEPreEAPSLPAARLRPRSg 230
Cdd:COG0363   157 TDRVVtldestrqanaRFFGSIPKVPPQAITLGIPTIMKAREILLLATGENKAEAVAAALEGP--VTEEVPASILQGHP- 233

                         250
                  ....*....|....
gi 1210014975 231 RLRWLLDREAAEEL 244
Cdd:COG0363   234 NVTWFLDEAAASLL 247
PLN02360 PLN02360
probable 6-phosphogluconolactonase
 4-244 1.09e-48

probable 6-phosphogluconolactonase


Pssm-ID: 166001 [Multi-domain]  Cd Length: 268  Bit Score: 161.56  E-value: 1.09e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975   4 VSVFPSPAELGAALARSVAEAAAEAVASGGRFTLGLSGGSLVALLARelpaaLRAAP---GAEPSRWLLAFCDERLVPPE 80
Cdd:PLN02360   13 IRVHENLDELSTDLAEYIAELSEASVKERGVFAIALSGGSLISFMGK-----LCEAPynkTVDWAKWYIFWADERVVAKN 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975  81 HPDSTGGAYRSQLLSQFAPPGPRVLWVSSGLGPAEAARDYEEQLRREFPGEA--------TPRFDLLLLGVGPDGHTCSL 152
Cdd:PLN02360   88 HADSNYKLAKDGLLSKVPVVPSHVYSINDTVTAEEAATDYEFAIRQLVKTRTigvsdisdCPKFDLILLGMGSDGHVASL 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975 153 FPGHALLQEQNSLISFLEDSPKPPPRRVTMTLPLLNAARALLVVATGASKAPVIKRILEEPRE--EAPSLPAARLRPRSG 230
Cdd:PLN02360  168 FPNHPALEEKDDWVTFITDSPKPPPERITFTLPVINSASNVAVVATGESKANAVHLAIDDVTEgpDAPSLPARMVQPTKG 247

                         250
                  ....*....|....
gi 1210014975 231 RLRWLLDREAAEEL 244
Cdd:PLN02360  248 KLVWFLDKPAASKL 261
 
Name Accession Description Interval E-value
Glucosamine_iso pfam01182
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
8-234 6.79e-74

Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;


Pssm-ID: 460101 [Multi-domain]  Cd Length: 222  Bit Score: 224.42  E-value: 6.79e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975   8 PSPAELGAALARSVAEAAAEAVASGGRFTLGLSGGSLVALLARELPAALRAAPgaePSRWLLAFCDERLVPPEHPDSTGG 87
Cdd:pfam01182   1 PDAEALAQALAERLAEALEAALAERGRFTLALSGGSTPKPLYELLAAAPARLD---WSRVHVFWGDERCVPPDDPDSNYG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975  88 AYRSQLLSQFAPPGPRVLWV-SSGLGPAEAARDYEEQLRREFPGEATPRFDLLLLGVGPDGHTCSLFPGHALLQEQNSLI 166
Cdd:pfam01182  78 MAREALLSHVPIPASNVHPIpASAADPEEAAAAYEAELRELLPDLELPVFDLVLLGMGPDGHTASLFPGSPALEETDRLV 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1210014975 167 SFLEDSPKPPPRRVTMTLPLLNAARALLVVATGASKAPVIKRILEeprEEAPSLPAARLRPRSGRLRW 234
Cdd:pfam01182 158 VAVTDSPKPPPERITLTLPVLNAARRVWFLVTGAGKADALRRALA---GDPDPLPAALVRPGAGETVW 222
6PGL cd01400
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the ...
 34-236 1.36e-72

6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the accumulation of the delta form of the lactone, which may be toxic through its reaction with endogenous cellular nucleophiles.


Pssm-ID: 238694 [Multi-domain]  Cd Length: 219  Bit Score: 220.90  E-value: 1.36e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975  34 RFTLGLSGGSLVALLARelpaALRAAPGAEPSRWLLAFCDERLVPPEHPDSTGGAYRSQLLSQFAPPGPRVLWVSSGLGP 113
Cdd:cd01400    24 RFSLALSGGSTPKPLYE----LLAAAPALDWSKVHVFLGDERCVPPDDPDSNYRLAREALLSHVAIPAANIHPIPTELGP 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975 114 AEAARDYEEQLRREFPGeaTPRFDLLLLGVGPDGHTCSLFPGH-ALLQEQNSLISFLEDSPKPPPRRVTMTLPLLNAARA 192
Cdd:cd01400   100 EDAAAAYEKELRALFGG--VPPFDLVLLGMGPDGHTASLFPGHpALLEETDRLVVAVTDSPKPPPERITLTLPVLNNARR 177

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1210014975 193 LLVVATGASKAPVIKRILEEPreEAPSLPAARLRPRSGRLRWLL 236
Cdd:cd01400   178 VVFLVTGAEKAEALKRALAGP--DPEELPAARVLPRPGEVLWFL 219
pgl TIGR01198
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a ...
 6-244 1.94e-60

6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a part of a multifunctional protein with [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273494 [Multi-domain]  Cd Length: 233  Bit Score: 190.28  E-value: 1.94e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975   6 VFPSPAELGAALARSVAEAAAEAVASGGRFTLGLSGGSLVALLARELPAAlraapGAEPSRWLLAFCDERLVPPEHPDST 85
Cdd:TIGR01198   1 VFSNSAELAEALAERIATKLQTALAERGQFSLALSGGRSPIALLEALAAQ-----PLDWSRIHLFLGDERYVPLDHADSN 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975  86 GGAYRSQLLSQFAPPGPRVLWVSSGLG-PAEAARDYEEQLRREFPGEATPRFDLLLLGVGPDGHTCSLFPGHALLQEQNS 164
Cdd:TIGR01198  76 TGLAREALLDRVAIPASNIHPMPTELSdIEEAAELYEQELAAAFQPIVFPVFDLLLLGMGPDGHTASLFPHTPALQETER 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975 165 LISFLEDSPKPPPRRVTMTLPLLNAARALLVVATGASKAPVIKRILEEprEEAPSLPAARLRPRSGRLRWLLDREAAEEL 244
Cdd:TIGR01198 156 LVTVLTKSPKPPHERITLTLPAINAARKVFLLIAGEEKRNALAEALAV--EAEPYPLPAAGVLHSGKTLWLLDYAAARKL 233
NagB COG0363
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport ...
 4-244 4.39e-53

6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440132 [Multi-domain]  Cd Length: 248  Bit Score: 171.88  E-value: 4.39e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975   4 VSVFPSPAELGAALARSVAEAAAEAVASGGRFTLGLSGGSLVALLARELpAALRAAPGAEPSRWLLAFCDERL-VPPEHP 82
Cdd:COG0363     4 VIIFPDAEELAAAAAERAAERIAEAIAEKGRAVLGLAGGSTPLGLYEEL-ARLHKEGGLDWSRVHVFNLDEYVgLPPDHP 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975  83 DSTGGAYRSQLLSQFAPPGPRV-LWVSSGLGPAEAARDYEEQLRrefpgeATPRFDLLLLGVGPDGHTCSLFPGHALLQE 161
Cdd:COG0363    83 QSNRRFMREALLDHVDIPPENIhIPDGEAEDPEAAAARYEALIA------EAGGIDLQLLGIGEDGHIAFNFPGSPFLSE 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975 162 QNSLI-----------SFLEDSPKPPPRRVTMTLPLLNAARALLVVATGASKAPVIKRILEEPreEAPSLPAARLRPRSg 230
Cdd:COG0363   157 TDRVVtldestrqanaRFFGSIPKVPPQAITLGIPTIMKAREILLLATGENKAEAVAAALEGP--VTEEVPASILQGHP- 233

                         250
                  ....*....|....
gi 1210014975 231 RLRWLLDREAAEEL 244
Cdd:COG0363   234 NVTWFLDEAAASLL 247
PLN02360 PLN02360
probable 6-phosphogluconolactonase
 4-244 1.09e-48

probable 6-phosphogluconolactonase


Pssm-ID: 166001 [Multi-domain]  Cd Length: 268  Bit Score: 161.56  E-value: 1.09e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975   4 VSVFPSPAELGAALARSVAEAAAEAVASGGRFTLGLSGGSLVALLARelpaaLRAAP---GAEPSRWLLAFCDERLVPPE 80
Cdd:PLN02360   13 IRVHENLDELSTDLAEYIAELSEASVKERGVFAIALSGGSLISFMGK-----LCEAPynkTVDWAKWYIFWADERVVAKN 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975  81 HPDSTGGAYRSQLLSQFAPPGPRVLWVSSGLGPAEAARDYEEQLRREFPGEA--------TPRFDLLLLGVGPDGHTCSL 152
Cdd:PLN02360   88 HADSNYKLAKDGLLSKVPVVPSHVYSINDTVTAEEAATDYEFAIRQLVKTRTigvsdisdCPKFDLILLGMGSDGHVASL 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975 153 FPGHALLQEQNSLISFLEDSPKPPPRRVTMTLPLLNAARALLVVATGASKAPVIKRILEEPRE--EAPSLPAARLRPRSG 230
Cdd:PLN02360  168 FPNHPALEEKDDWVTFITDSPKPPPERITFTLPVINSASNVAVVATGESKANAVHLAIDDVTEgpDAPSLPARMVQPTKG 247

                         250
                  ....*....|....
gi 1210014975 231 RLRWLLDREAAEEL 244
Cdd:PLN02360  248 KLVWFLDKPAASKL 261
GlcN6P_deaminase cd01399
GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase ...
 34-244 4.48e-18

GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.


Pssm-ID: 238693 [Multi-domain]  Cd Length: 232  Bit Score: 80.22  E-value: 4.48e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975  34 RFTLGLSGGSLVALLARELpAALRAAPGAEPSRWLLAFCDERL-VPPEHPDSTGGAYRSQLLSQ--------FAPPGprv 104
Cdd:cd01399    20 PAVLGLATGSTPLGVYEEL-IELHKEGGLSFSNVTTFNLDEYVgLPPDHPQSYHYFMRENLFDHidikpeniHIPDG--- 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975 105 lwvsSGLGPAEAARDYEEQLRrefpgEATPRfDLLLLGVGPDGHTCslF--PGHAL--------LQEQ--NSLISFLEDS 172
Cdd:cd01399    96 ----NAADLEAECRRYEALIA-----EAGGI-DLQLLGIGENGHIG--FnePGSSLdsrtrvvtLDEStrQANARFFDGD 163

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1210014975 173 PKPPPRRVTMTLPLLNAARALLVVATGASKAPVIKRILEEPreEAPSLPAARLRpRSGRLRWLLDREAAEEL 244
Cdd:cd01399   164 EDVPTQAITMGIGTIMKAKEILLLATGEGKAEAVKKALEGP--VTEECPASILQ-LHPNVTVILDEAAASEL 232
PRK12358 PRK12358
glucosamine-6-phosphate deaminase;
114-246 1.59e-13

glucosamine-6-phosphate deaminase;


Pssm-ID: 183470  Cd Length: 239  Bit Score: 67.85  E-value: 1.59e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975 114 AEAARDYEEQLRREfpgeatPRFDLLLLGVGPDGHTCSLFPGHALLQEQNSLISFLEDSP-------------KPPPRRV 180
Cdd:PRK12358  103 IDNYREHDQKLARD------GGLDLVVLGLGADGHFCGNLPGTTHFHDETVEVPIQGEMVdivahgelggdfsLVPDSYV 176

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1210014975 181 TMTLPLLNAARALLVVATGASKAPVIKRILEEP-REEAPSlPAARLRPrsgRLRWLLDREAAEELRL 246
Cdd:PRK12358  177 TMGPKSIMAAKNLLLIVNGKGKAQILKKVLQGPvTEDVPA-SILQLHP---NLTVILDEAAAAELAL 239
nagB PRK00443
glucosamine-6-phosphate deaminase; Provisional
 4-246 8.95e-13

glucosamine-6-phosphate deaminase; Provisional


Pssm-ID: 179028 [Multi-domain]  Cd Length: 261  Bit Score: 66.01  E-value: 8.95e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975   4 VSVFPSPAELGAALARSVAEAAAEAVASGGR-FTLGL-SGGSLVALLArELpAALRAAPGAEPSRwLLAF-CDERL-VPP 79
Cdd:PRK00443    3 LIILKTAEEVGKWAARHIANRINAFLPTKERpFVLGLaTGSSPLETYK-AL-IELHKAGKVDFSR-VTTFnLDEYVgLPA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975  80 EHPDStggaYRSQLLSQFA---PPGPRVLWVSSGLG--PAEAARDYEEQLRrefpgeATPRFDLLLLGVGPDGHTCslF- 153
Cdd:PRK00443   80 DHPES----YRYFMRENFFdhvDIPPENINLLNGNApdPEAECRRYEEKIK------SAGGIDLQILGIGENGHIA--Fn 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975 154 -PGHAL--------LQEQ----NSLI--SFLEDSPKpppRRVTMTLPLLNAARALLVVATGASKAPVIKRILEEPREEAP 218
Cdd:PRK00443  148 ePGSSFasrtriktLTEDtriaNSRFfdGDIEQVPK---YALTVGVGTILDAKEIMLLAPGHNKAEAVKAAVEGPVNHMW 224

                         250       260
                  ....*....|....*....|....*...
gi 1210014975 219 SLPAARLRPRSgrlRWLLDREAAEELRL 246
Cdd:PRK00443  225 PASILQLHPKA---TLVLDEAAASELKV 249
PTZ00285 PTZ00285
glucosamine-6-phosphate isomerase; Provisional
 78-245 4.32e-08

glucosamine-6-phosphate isomerase; Provisional


Pssm-ID: 140308  Cd Length: 253  Bit Score: 52.45  E-value: 4.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975  78 PPEHPDStggaYRSQLLSQF-----APPGPRVLWvsSGLGP--AEAARDYEEQLRrefpgeATPRFDLLLLGVGPDGHTC 150
Cdd:PTZ00285   78 PRDHPQS----YHYFMKENFfdhvdIKEENRHIL--NGTAPdlEEECRRYEEKIR------AVGGIDLFLAGIGTDGHIA 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975 151 SLFPGHALLQE-------QNSLIS----FLEDSPKPPPRRVTMTLPLLNAARALLVVATGASKAPVIKRILEEPREEAPS 219
Cdd:PTZ00285  146 FNEPGSSLDSRtrvkslnQETIDAnarfFGNDISKVPTMALTVGIRTIMEAREVLLLATGASKAIAVARCVEGGVTHMCP 225

                         170       180
                  ....*....|....*....|....*.
gi 1210014975 220 LPAARLRPRSgrlRWLLDREAAEELR 245
Cdd:PTZ00285  226 ASALQMHPAA---VLCLDEDATLELK 248
PRK02122 PRK02122
glucosamine-6-phosphate deaminase-like protein; Validated
 114-244 7.25e-06

glucosamine-6-phosphate deaminase-like protein; Validated


Pssm-ID: 235005 [Multi-domain]  Cd Length: 652  Bit Score: 46.56  E-value: 7.25e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975 114 AEAARDYEEQLRReFPGeatprFDLLLLGVGPDGHTCSLFPGHAL-----------LQEQNSLISFLeDSPKPPPRRVTM 182
Cdd:PRK02122  143 DEYCRDYEEKIEA-AGG-----IDFQLLGIGRTGHIGFNEPGSGRnsrtrlvtldhITRRDAASDFF-GEENVPRKAITM 215

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1210014975 183 TLPLLNAARALLVVATGASKAPVIKRILEEprEEAPSLPAARLRpRSGRLRWLLDREAAEEL 244
Cdd:PRK02122  216 GVGTILKARRIVLLAWGEHKAPIIKRAVEG--EISDEVPASYLQ-EHPNATFVLDLAAASEL 274
SugarP_isomerase cd00458
SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate ...
 35-149 4.36e-04

SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium, the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate. 6PGL converts 6-phosphoglucono-1,5-lactone to 6-phosphogluconate, the second step of the oxidative phase of the pentose phosphate pathway.


Pssm-ID: 238258  Cd Length: 169  Bit Score: 40.03  E-value: 4.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1210014975  35 FTLGLSGGSLVALLARELPAALRAApgaEPSRWLLAFCDERLVPPEHPDSTGGAYRSQLLSQFAPPGPRVLWVSSGLGPA 114
Cdd:cd00458    22 MVIGLGTGSTPAYFYKLLGEKLKRG---EISDIVGFPTDERYVPLDSDQSNFRQAKLLAFEHDIIPASNVHYVDTSLPIE 98

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1210014975 115 EAARDYEEQLRRefpgeATPRFDLLLLGVGPDGHT 149
Cdd:cd00458    99 KACEKYEREILD-----QVDAIDLAVDGAGYRAGT 128
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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