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Conserved domains on  [gi|1199386498|ref|XP_021188018|]
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mediator of RNA polymerase II transcription subunit 23 [Helicoverpa armigera]

Protein Classification

Med23 domain-containing protein( domain architecture ID 10569018)

Med23 domain-containing protein

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Med23 pfam11573
Mediator complex subunit 23; Med23 is one of the subunits of the Tail portion of the Mediator ...
 3-1300 0e+00

Mediator complex subunit 23; Med23 is one of the subunits of the Tail portion of the Mediator complex that regulates RNA polymerase II activity. Med23 is required for heat-shock-specific gene expression, and has been shown to mediate transcriptional activation of E1A in mice.


:

Pssm-ID: 463299  Cd Length: 1301  Bit Score: 2196.77  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498    3 DSQVANIVSEILRVEAVEEAFSCFLVHKPEEENETLAMYQKRLCGVMTNLSAELQESALRQYLTPAAVLTNRYKMKQLLG 82
Cdd:pfam11573    2 VNQVKSIINEILKVEIIEEAFSGFTSNLPDDEKEKTAILRKQFNNMMSKMSEEEKESLVKELIKLVHHVAEKNRLDFLFQ 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498   83 LLETLVNTNVIQARMLCDCILTNEKLVYKNADFWIESFNLIRRIIGGVDYKGVREIMKGCREKAHTLPVRLNSSTMPQLK 162
Cdd:pfam11573   82 LLEYAVQKGIISARLVCEGLIMSEKLVLCNRLFWQECFKLIRKIIPGVDYKGVREILKYCLEKARRLPYSLSPEKVPQLR 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  163 ALYNVIEYIFDRNASLLPAYFIVTEIQKDYPGNNHWPHWQLAKLLSSFVESFKPCAQMVSIIGHSQMLPVVEFSGYADHL 242
Cdd:pfam11573  162 ALENVILYILDRNACLLPAYFIVNEIMKGYPDAKMWPHWRLAELLSNFVESFRPIAQMVSIIGRSFMLPVVEHSGYADHL 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  243 VNPWRLDPTTLKFSLKGNLPYDEELLKPQIALLRHVLQQPYSRDMMCSMLGLQKQHKQRCIALEDQLVELMILPMEKSeq 322
Cdd:pfam11573  242 TSPWKLDPATLKFQLKGNLPYRPELLEPQTYLLRYVLEQPYSRDMVCSMLGLQKQHKQRCKALEEQLVELMICAMERS-- 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  323 ENEDDEMSSSHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLIGHDMKKGRDHLMWVLLQFISGSIQRNPSSNFLPIIK 402
Cdd:pfam11573  320 ETEPEDEPITHWLWLHLSSQLIYFVLFQFASFPNIVKSLHEKLAGRDLTRGRDHLMWVLLQFISGSIQKNPLSDFLPILK 399

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  403 LYELLYPEKEPLPVPDCTKAHSTHQMAVVCIWMHLLKKAETEHKTMT--MPQNLKVQYEFLQHLMTSNNTPTL-MGSDYR 479
Cdd:pfam11573  400 LYDLLYPEKEPLPVPDYNKPLCTHQMAATCIWIHLLKKAQDENQKLQrpIPDTLKSHHEFLQHLVLNNDSPNLaMGSDYR 479

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  480 IALLCNAYSTNQEYFARPMGVIIETLFGNQKPMPNGnPTTPLPNVPLSMCILDSLTLHCKMSLIHSIVTHVAKLAQNKSN 559
Cdd:pfam11573  480 IALLCNAYSTNTEYFSRPMPALVETILGNSKSRSPG-CNAPGPTTPLSMEFLDSLTVHSKMSLIHSIVTHVIKFAQSKSS 558

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  560 MPgnnmMAPALVETYSRLLVYTEIESMGIKGFIHQLLPNVFKSHAWGILHNLLDMFSYRIHHVQPHYRVTLLSNIHSLAA 639
Cdd:pfam11573  559 VA----LAPALVETYSRLLVYTEIESLGIKGFISQLLPTVFKSQAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAN 634

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  640 YPQANQTQLQLCFESTALRLITSLGSSGVQLQMSRVVSEPK-SLVSSESEELNRVLVLTLARGIYMTGAGSDGAA-VKEL 717
Cdd:pfam11573  635 VPQTNQTQLHLCVESTALRLITGLGSSEVQPQLSRFLNEPKtFLVSQESEELNRALILTLARAIHITGTGTDSESwCKEL 714

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  718 LTTIMTNTPHMWSQHTLQCFPPMLVEFFAQNPAPKENKQVLKKSVEEEYRKWTSMANDNDIISHFSVPGTP-LFLCLLWK 796
Cdd:pfam11573  715 LETIMQNTPHGWPQHTLSCFPPWLLEFFKQNNVPKENKQQLKKNVEEEYRKWTSMTNENDIIAHFSVPGTPpLFLCLLWK 794

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  797 MIFETNRINPVAFKILERIGARALSAHLRKFCDYLVFEVTNPAGGPHINKCVDAINDIIWKYNIVTIDRLVLCLVLRPNp 876
Cdd:pfam11573  795 MLLETDRITPIAYKVLERIGARALSAHLRKFCDYLVFEFTNSCGGQHVNKCADALNDMIWKYNIVTIDRLVLCLALRPQ- 873

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  877 DGNEGQVCLYIIQLLLLKGSELRNRAQDFVKENSPEHWKQNNWYDKHLAFHRKYPEKFAPEEAG---TAYGGPIPVYLSN 953
Cdd:pfam11573  874 EGNEAQVCFFIIQLLLLKTTEFRNRVQDFVKENSPEHWKQPNWHEKHLAYHRKFPEKFAPEGVAeydSSSNPYLPTYFGN 953

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  954 VCLRFLPVLDIVVHRHLEIPSVCKNLEQLLEHLGYLYKFHDRPVTFLYNTLHYYESKLRDKPLLKRKLVNAVLGSLKDVR 1033
Cdd:pfam11573  954 VCLRFLPVLDIVIHRALELPPVSKSLETLLEHLGCLYKFHDRPVTYLYNTLHYYEHKLRDRPDLKRKLVSAIIGSLKDCR 1033

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498 1034 PAGWATTETFQTFLAKSEVDATAWTPDlNYYLTLVNRMVDTMTGSS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPL 1111
Cdd:pfam11573 1034 PPGWALTEAYEKYHQKSSDEQLIWLPE-DYYMKLIDRMVDTMDGKTppPFPAKDWRFNEFPNPGAHALYVTCVELMALPV 1112

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498 1112 APNFVGNALLDVVTKGFVVIPATKIQLWINAIGLIMAALPDPYWTVIHDRILELMTNNEMTEWPYPHTPFQLFNLTITND 1191
Cdd:pfam11573 1113 SPETVANALIDVVQKGYHLIPRNQIHLWINAIGLILTALPESYWSVLHDRIVEVLSNPELTNWTYPCSPFELFNFDNYHE 1192

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498 1192 ALLENKYSLTLALAHAIWYHAGAGQIMQIPVFVKEKLSVEIHSEVQLLYLCHLVGPFLQRFNSDLSRAVMDITITLYELL 1271
Cdd:pfam11573 1193 SLLENRASYILALAHAVWHHAGIGQLNPFPQFVKEKLLPHVKTEEQLLYLCHLVGPFLQRFRAERERGVLDITKLLYELL 1272

                         1290      1300
                   ....*....|....*....|....*....
gi 1199386498 1272 AHIDKSQQHLQYIDPICDLLYHIKYMFVG 1300
Cdd:pfam11573 1273 EQVDKEGVELRYMDPICDLLYHIKYMFVG 1301
 
Name Accession Description Interval E-value
Med23 pfam11573
Mediator complex subunit 23; Med23 is one of the subunits of the Tail portion of the Mediator ...
 3-1300 0e+00

Mediator complex subunit 23; Med23 is one of the subunits of the Tail portion of the Mediator complex that regulates RNA polymerase II activity. Med23 is required for heat-shock-specific gene expression, and has been shown to mediate transcriptional activation of E1A in mice.


Pssm-ID: 463299  Cd Length: 1301  Bit Score: 2196.77  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498    3 DSQVANIVSEILRVEAVEEAFSCFLVHKPEEENETLAMYQKRLCGVMTNLSAELQESALRQYLTPAAVLTNRYKMKQLLG 82
Cdd:pfam11573    2 VNQVKSIINEILKVEIIEEAFSGFTSNLPDDEKEKTAILRKQFNNMMSKMSEEEKESLVKELIKLVHHVAEKNRLDFLFQ 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498   83 LLETLVNTNVIQARMLCDCILTNEKLVYKNADFWIESFNLIRRIIGGVDYKGVREIMKGCREKAHTLPVRLNSSTMPQLK 162
Cdd:pfam11573   82 LLEYAVQKGIISARLVCEGLIMSEKLVLCNRLFWQECFKLIRKIIPGVDYKGVREILKYCLEKARRLPYSLSPEKVPQLR 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  163 ALYNVIEYIFDRNASLLPAYFIVTEIQKDYPGNNHWPHWQLAKLLSSFVESFKPCAQMVSIIGHSQMLPVVEFSGYADHL 242
Cdd:pfam11573  162 ALENVILYILDRNACLLPAYFIVNEIMKGYPDAKMWPHWRLAELLSNFVESFRPIAQMVSIIGRSFMLPVVEHSGYADHL 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  243 VNPWRLDPTTLKFSLKGNLPYDEELLKPQIALLRHVLQQPYSRDMMCSMLGLQKQHKQRCIALEDQLVELMILPMEKSeq 322
Cdd:pfam11573  242 TSPWKLDPATLKFQLKGNLPYRPELLEPQTYLLRYVLEQPYSRDMVCSMLGLQKQHKQRCKALEEQLVELMICAMERS-- 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  323 ENEDDEMSSSHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLIGHDMKKGRDHLMWVLLQFISGSIQRNPSSNFLPIIK 402
Cdd:pfam11573  320 ETEPEDEPITHWLWLHLSSQLIYFVLFQFASFPNIVKSLHEKLAGRDLTRGRDHLMWVLLQFISGSIQKNPLSDFLPILK 399

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  403 LYELLYPEKEPLPVPDCTKAHSTHQMAVVCIWMHLLKKAETEHKTMT--MPQNLKVQYEFLQHLMTSNNTPTL-MGSDYR 479
Cdd:pfam11573  400 LYDLLYPEKEPLPVPDYNKPLCTHQMAATCIWIHLLKKAQDENQKLQrpIPDTLKSHHEFLQHLVLNNDSPNLaMGSDYR 479

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  480 IALLCNAYSTNQEYFARPMGVIIETLFGNQKPMPNGnPTTPLPNVPLSMCILDSLTLHCKMSLIHSIVTHVAKLAQNKSN 559
Cdd:pfam11573  480 IALLCNAYSTNTEYFSRPMPALVETILGNSKSRSPG-CNAPGPTTPLSMEFLDSLTVHSKMSLIHSIVTHVIKFAQSKSS 558

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  560 MPgnnmMAPALVETYSRLLVYTEIESMGIKGFIHQLLPNVFKSHAWGILHNLLDMFSYRIHHVQPHYRVTLLSNIHSLAA 639
Cdd:pfam11573  559 VA----LAPALVETYSRLLVYTEIESLGIKGFISQLLPTVFKSQAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAN 634

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  640 YPQANQTQLQLCFESTALRLITSLGSSGVQLQMSRVVSEPK-SLVSSESEELNRVLVLTLARGIYMTGAGSDGAA-VKEL 717
Cdd:pfam11573  635 VPQTNQTQLHLCVESTALRLITGLGSSEVQPQLSRFLNEPKtFLVSQESEELNRALILTLARAIHITGTGTDSESwCKEL 714

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  718 LTTIMTNTPHMWSQHTLQCFPPMLVEFFAQNPAPKENKQVLKKSVEEEYRKWTSMANDNDIISHFSVPGTP-LFLCLLWK 796
Cdd:pfam11573  715 LETIMQNTPHGWPQHTLSCFPPWLLEFFKQNNVPKENKQQLKKNVEEEYRKWTSMTNENDIIAHFSVPGTPpLFLCLLWK 794

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  797 MIFETNRINPVAFKILERIGARALSAHLRKFCDYLVFEVTNPAGGPHINKCVDAINDIIWKYNIVTIDRLVLCLVLRPNp 876
Cdd:pfam11573  795 MLLETDRITPIAYKVLERIGARALSAHLRKFCDYLVFEFTNSCGGQHVNKCADALNDMIWKYNIVTIDRLVLCLALRPQ- 873

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  877 DGNEGQVCLYIIQLLLLKGSELRNRAQDFVKENSPEHWKQNNWYDKHLAFHRKYPEKFAPEEAG---TAYGGPIPVYLSN 953
Cdd:pfam11573  874 EGNEAQVCFFIIQLLLLKTTEFRNRVQDFVKENSPEHWKQPNWHEKHLAYHRKFPEKFAPEGVAeydSSSNPYLPTYFGN 953

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  954 VCLRFLPVLDIVVHRHLEIPSVCKNLEQLLEHLGYLYKFHDRPVTFLYNTLHYYESKLRDKPLLKRKLVNAVLGSLKDVR 1033
Cdd:pfam11573  954 VCLRFLPVLDIVIHRALELPPVSKSLETLLEHLGCLYKFHDRPVTYLYNTLHYYEHKLRDRPDLKRKLVSAIIGSLKDCR 1033

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498 1034 PAGWATTETFQTFLAKSEVDATAWTPDlNYYLTLVNRMVDTMTGSS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPL 1111
Cdd:pfam11573 1034 PPGWALTEAYEKYHQKSSDEQLIWLPE-DYYMKLIDRMVDTMDGKTppPFPAKDWRFNEFPNPGAHALYVTCVELMALPV 1112

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498 1112 APNFVGNALLDVVTKGFVVIPATKIQLWINAIGLIMAALPDPYWTVIHDRILELMTNNEMTEWPYPHTPFQLFNLTITND 1191
Cdd:pfam11573 1113 SPETVANALIDVVQKGYHLIPRNQIHLWINAIGLILTALPESYWSVLHDRIVEVLSNPELTNWTYPCSPFELFNFDNYHE 1192

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498 1192 ALLENKYSLTLALAHAIWYHAGAGQIMQIPVFVKEKLSVEIHSEVQLLYLCHLVGPFLQRFNSDLSRAVMDITITLYELL 1271
Cdd:pfam11573 1193 SLLENRASYILALAHAVWHHAGIGQLNPFPQFVKEKLLPHVKTEEQLLYLCHLVGPFLQRFRAERERGVLDITKLLYELL 1272

                         1290      1300
                   ....*....|....*....|....*....
gi 1199386498 1272 AHIDKSQQHLQYIDPICDLLYHIKYMFVG 1300
Cdd:pfam11573 1273 EQVDKEGVELRYMDPICDLLYHIKYMFVG 1301
 
Name Accession Description Interval E-value
Med23 pfam11573
Mediator complex subunit 23; Med23 is one of the subunits of the Tail portion of the Mediator ...
 3-1300 0e+00

Mediator complex subunit 23; Med23 is one of the subunits of the Tail portion of the Mediator complex that regulates RNA polymerase II activity. Med23 is required for heat-shock-specific gene expression, and has been shown to mediate transcriptional activation of E1A in mice.


Pssm-ID: 463299  Cd Length: 1301  Bit Score: 2196.77  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498    3 DSQVANIVSEILRVEAVEEAFSCFLVHKPEEENETLAMYQKRLCGVMTNLSAELQESALRQYLTPAAVLTNRYKMKQLLG 82
Cdd:pfam11573    2 VNQVKSIINEILKVEIIEEAFSGFTSNLPDDEKEKTAILRKQFNNMMSKMSEEEKESLVKELIKLVHHVAEKNRLDFLFQ 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498   83 LLETLVNTNVIQARMLCDCILTNEKLVYKNADFWIESFNLIRRIIGGVDYKGVREIMKGCREKAHTLPVRLNSSTMPQLK 162
Cdd:pfam11573   82 LLEYAVQKGIISARLVCEGLIMSEKLVLCNRLFWQECFKLIRKIIPGVDYKGVREILKYCLEKARRLPYSLSPEKVPQLR 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  163 ALYNVIEYIFDRNASLLPAYFIVTEIQKDYPGNNHWPHWQLAKLLSSFVESFKPCAQMVSIIGHSQMLPVVEFSGYADHL 242
Cdd:pfam11573  162 ALENVILYILDRNACLLPAYFIVNEIMKGYPDAKMWPHWRLAELLSNFVESFRPIAQMVSIIGRSFMLPVVEHSGYADHL 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  243 VNPWRLDPTTLKFSLKGNLPYDEELLKPQIALLRHVLQQPYSRDMMCSMLGLQKQHKQRCIALEDQLVELMILPMEKSeq 322
Cdd:pfam11573  242 TSPWKLDPATLKFQLKGNLPYRPELLEPQTYLLRYVLEQPYSRDMVCSMLGLQKQHKQRCKALEEQLVELMICAMERS-- 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  323 ENEDDEMSSSHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLIGHDMKKGRDHLMWVLLQFISGSIQRNPSSNFLPIIK 402
Cdd:pfam11573  320 ETEPEDEPITHWLWLHLSSQLIYFVLFQFASFPNIVKSLHEKLAGRDLTRGRDHLMWVLLQFISGSIQKNPLSDFLPILK 399

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  403 LYELLYPEKEPLPVPDCTKAHSTHQMAVVCIWMHLLKKAETEHKTMT--MPQNLKVQYEFLQHLMTSNNTPTL-MGSDYR 479
Cdd:pfam11573  400 LYDLLYPEKEPLPVPDYNKPLCTHQMAATCIWIHLLKKAQDENQKLQrpIPDTLKSHHEFLQHLVLNNDSPNLaMGSDYR 479

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  480 IALLCNAYSTNQEYFARPMGVIIETLFGNQKPMPNGnPTTPLPNVPLSMCILDSLTLHCKMSLIHSIVTHVAKLAQNKSN 559
Cdd:pfam11573  480 IALLCNAYSTNTEYFSRPMPALVETILGNSKSRSPG-CNAPGPTTPLSMEFLDSLTVHSKMSLIHSIVTHVIKFAQSKSS 558

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  560 MPgnnmMAPALVETYSRLLVYTEIESMGIKGFIHQLLPNVFKSHAWGILHNLLDMFSYRIHHVQPHYRVTLLSNIHSLAA 639
Cdd:pfam11573  559 VA----LAPALVETYSRLLVYTEIESLGIKGFISQLLPTVFKSQAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAN 634

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  640 YPQANQTQLQLCFESTALRLITSLGSSGVQLQMSRVVSEPK-SLVSSESEELNRVLVLTLARGIYMTGAGSDGAA-VKEL 717
Cdd:pfam11573  635 VPQTNQTQLHLCVESTALRLITGLGSSEVQPQLSRFLNEPKtFLVSQESEELNRALILTLARAIHITGTGTDSESwCKEL 714

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  718 LTTIMTNTPHMWSQHTLQCFPPMLVEFFAQNPAPKENKQVLKKSVEEEYRKWTSMANDNDIISHFSVPGTP-LFLCLLWK 796
Cdd:pfam11573  715 LETIMQNTPHGWPQHTLSCFPPWLLEFFKQNNVPKENKQQLKKNVEEEYRKWTSMTNENDIIAHFSVPGTPpLFLCLLWK 794

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  797 MIFETNRINPVAFKILERIGARALSAHLRKFCDYLVFEVTNPAGGPHINKCVDAINDIIWKYNIVTIDRLVLCLVLRPNp 876
Cdd:pfam11573  795 MLLETDRITPIAYKVLERIGARALSAHLRKFCDYLVFEFTNSCGGQHVNKCADALNDMIWKYNIVTIDRLVLCLALRPQ- 873

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  877 DGNEGQVCLYIIQLLLLKGSELRNRAQDFVKENSPEHWKQNNWYDKHLAFHRKYPEKFAPEEAG---TAYGGPIPVYLSN 953
Cdd:pfam11573  874 EGNEAQVCFFIIQLLLLKTTEFRNRVQDFVKENSPEHWKQPNWHEKHLAYHRKFPEKFAPEGVAeydSSSNPYLPTYFGN 953

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498  954 VCLRFLPVLDIVVHRHLEIPSVCKNLEQLLEHLGYLYKFHDRPVTFLYNTLHYYESKLRDKPLLKRKLVNAVLGSLKDVR 1033
Cdd:pfam11573  954 VCLRFLPVLDIVIHRALELPPVSKSLETLLEHLGCLYKFHDRPVTYLYNTLHYYEHKLRDRPDLKRKLVSAIIGSLKDCR 1033

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498 1034 PAGWATTETFQTFLAKSEVDATAWTPDlNYYLTLVNRMVDTMTGSS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPL 1111
Cdd:pfam11573 1034 PPGWALTEAYEKYHQKSSDEQLIWLPE-DYYMKLIDRMVDTMDGKTppPFPAKDWRFNEFPNPGAHALYVTCVELMALPV 1112

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498 1112 APNFVGNALLDVVTKGFVVIPATKIQLWINAIGLIMAALPDPYWTVIHDRILELMTNNEMTEWPYPHTPFQLFNLTITND 1191
Cdd:pfam11573 1113 SPETVANALIDVVQKGYHLIPRNQIHLWINAIGLILTALPESYWSVLHDRIVEVLSNPELTNWTYPCSPFELFNFDNYHE 1192

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199386498 1192 ALLENKYSLTLALAHAIWYHAGAGQIMQIPVFVKEKLSVEIHSEVQLLYLCHLVGPFLQRFNSDLSRAVMDITITLYELL 1271
Cdd:pfam11573 1193 SLLENRASYILALAHAVWHHAGIGQLNPFPQFVKEKLLPHVKTEEQLLYLCHLVGPFLQRFRAERERGVLDITKLLYELL 1272

                         1290      1300
                   ....*....|....*....|....*....
gi 1199386498 1272 AHIDKSQQHLQYIDPICDLLYHIKYMFVG 1300
Cdd:pfam11573 1273 EQVDKEGVELRYMDPICDLLYHIKYMFVG 1301
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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