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Conserved domains on  [gi|1195507546|ref|XP_021066313|]
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SERTA domain-containing protein 2 [Mus pahari]

Protein Classification

SERTA domain-containing protein( domain architecture ID 10532710)

SERTA domain-containing protein similar to Homo sapiens cell division cycle associated 4 (CDCA4) that may participate in the regulation of cell proliferation through the E2F/RB pathway

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SERTA pfam06031
SERTA motif; This family consists of a novel motif designated as SERTA (for SEI-1, RBT1, and ...
 40-75 1.21e-15

SERTA motif; This family consists of a novel motif designated as SERTA (for SEI-1, RBT1, and TARA), corresponding to the largest conserved region among TRIP-Br proteins. The function of this motif is uncertain, but the CDK4-interacting segment of p34SEI-1 (amino acid residues 44-161) includes most of the SERTA motif.


:

Pssm-ID: 461806  Cd Length: 36  Bit Score: 69.49  E-value: 1.21e-15
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1195507546  40 IFNISLMKLYNHRPLTEPSLQKTVLINNMLRRIQEE 75
Cdd:pfam06031   1 VLNLSLDKLQRSRDLVEPSLRRSVLINNTLRRIQDE 36
AvrBs3 super family cl49339
type III secretion system effector avirulence protein AvrBs3;
73-215 3.37e-03

type III secretion system effector avirulence protein AvrBs3;


The actual alignment was detected with superfamily member NF041308:

Pssm-ID: 469205 [Multi-domain]  Cd Length: 1179  Bit Score: 39.17  E-value: 3.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1195507546   73 QEELKQEGSLRPAFTPSSQPSDSLS-----DSYREVPPPAPHPC-DLGSTTPLEACLTPASLLEDDDDTFCTLQAVHPAA 146
Cdd:NF041308    20 QPDGVQPIAGRLVSTAASSPLDGLParpamSRTRQPATPAPSPAfSVGSFSDLLRQFDPSLFDPSLFDSSPAFGAHHADA 99

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1195507546  147 ptrlssptLPAEKDSFSSALDEIEELCPTSTSTEAAPTAAPEGSKGTSSESSVQKPDGPQEGRTDDSRF 215
Cdd:NF041308   100 --------APGEMDEVQSGLRAADDPQSHLSAAVTAPSPTPPRTQAAARRRSAQTSDASPAESVDLSTL 160
 
Name Accession Description Interval E-value
SERTA pfam06031
SERTA motif; This family consists of a novel motif designated as SERTA (for SEI-1, RBT1, and ...
 40-75 1.21e-15

SERTA motif; This family consists of a novel motif designated as SERTA (for SEI-1, RBT1, and TARA), corresponding to the largest conserved region among TRIP-Br proteins. The function of this motif is uncertain, but the CDK4-interacting segment of p34SEI-1 (amino acid residues 44-161) includes most of the SERTA motif.


Pssm-ID: 461806  Cd Length: 36  Bit Score: 69.49  E-value: 1.21e-15
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1195507546  40 IFNISLMKLYNHRPLTEPSLQKTVLINNMLRRIQEE 75
Cdd:pfam06031   1 VLNLSLDKLQRSRDLVEPSLRRSVLINNTLRRIQDE 36
AvrBs3 NF041308
type III secretion system effector avirulence protein AvrBs3;
73-215 3.37e-03

type III secretion system effector avirulence protein AvrBs3;


Pssm-ID: 469205 [Multi-domain]  Cd Length: 1179  Bit Score: 39.17  E-value: 3.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1195507546   73 QEELKQEGSLRPAFTPSSQPSDSLS-----DSYREVPPPAPHPC-DLGSTTPLEACLTPASLLEDDDDTFCTLQAVHPAA 146
Cdd:NF041308    20 QPDGVQPIAGRLVSTAASSPLDGLParpamSRTRQPATPAPSPAfSVGSFSDLLRQFDPSLFDPSLFDSSPAFGAHHADA 99

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1195507546  147 ptrlssptLPAEKDSFSSALDEIEELCPTSTSTEAAPTAAPEGSKGTSSESSVQKPDGPQEGRTDDSRF 215
Cdd:NF041308   100 --------APGEMDEVQSGLRAADDPQSHLSAAVTAPSPTPPRTQAAARRRSAQTSDASPAESVDLSTL 160
 
Name Accession Description Interval E-value
SERTA pfam06031
SERTA motif; This family consists of a novel motif designated as SERTA (for SEI-1, RBT1, and ...
 40-75 1.21e-15

SERTA motif; This family consists of a novel motif designated as SERTA (for SEI-1, RBT1, and TARA), corresponding to the largest conserved region among TRIP-Br proteins. The function of this motif is uncertain, but the CDK4-interacting segment of p34SEI-1 (amino acid residues 44-161) includes most of the SERTA motif.


Pssm-ID: 461806  Cd Length: 36  Bit Score: 69.49  E-value: 1.21e-15
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1195507546  40 IFNISLMKLYNHRPLTEPSLQKTVLINNMLRRIQEE 75
Cdd:pfam06031   1 VLNLSLDKLQRSRDLVEPSLRRSVLINNTLRRIQDE 36
AvrBs3 NF041308
type III secretion system effector avirulence protein AvrBs3;
73-215 3.37e-03

type III secretion system effector avirulence protein AvrBs3;


Pssm-ID: 469205 [Multi-domain]  Cd Length: 1179  Bit Score: 39.17  E-value: 3.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1195507546   73 QEELKQEGSLRPAFTPSSQPSDSLS-----DSYREVPPPAPHPC-DLGSTTPLEACLTPASLLEDDDDTFCTLQAVHPAA 146
Cdd:NF041308    20 QPDGVQPIAGRLVSTAASSPLDGLParpamSRTRQPATPAPSPAfSVGSFSDLLRQFDPSLFDPSLFDSSPAFGAHHADA 99

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1195507546  147 ptrlssptLPAEKDSFSSALDEIEELCPTSTSTEAAPTAAPEGSKGTSSESSVQKPDGPQEGRTDDSRF 215
Cdd:NF041308   100 --------APGEMDEVQSGLRAADDPQSHLSAAVTAPSPTPPRTQAAARRRSAQTSDASPAESVDLSTL 160
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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