NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1176269710|ref|XP_020636582|]
View 

N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 isoform X2 [Pogona vitticeps]

Protein Classification

glycosyltransferase family protein( domain architecture ID 229488)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Galactosyl_T super family cl21608
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
 126-318 2.54e-41

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


The actual alignment was detected with superfamily member pfam01762:

Pssm-ID: 473923 [Multi-domain]  Cd Length: 195  Bit Score: 144.00  E-value: 2.54e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176269710 126 ERREVIRKTWGQERTVAGVHIRRVFLSGVAANAreARKLNGLLAMEAAEHRDILQWGFQDSFFNLTLKQSLFHAWLDARC 205
Cdd:pfam01762   1 ARRNAIRKTWMNQGNSEGGRIKSLFLVGLSADT--DGKVADLVMEEAKLYGDIVVVDFEDTYENLTFKTLTGLLWAVSKC 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176269710 206 PGVRFVLNGDDDVFAHTDNMVHYLLGVPGAGDRHLFVGHLISHVGPIREKWSKYYVPELVTASKSYPPYCGGGGLLMSGF 285
Cdd:pfam01762  79 PSAKYIGKIDDDVYFFPDKLLSLLDNGNIDPSESSFYGYVMEEGPVIRNKKSKWYVSPSDYKCSRYPPYASGPFYVLSRD 158

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1176269710 286 TSRAIYQASLDLELFPIDDVYLGMCLQKAGLAP 318
Cdd:pfam01762 159 AAEKLLKASKHRRFLQIEDVYVGILANDLGISR 191
 
Name Accession Description Interval E-value
Galactosyl_T pfam01762
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
 126-318 2.54e-41

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


Pssm-ID: 426415 [Multi-domain]  Cd Length: 195  Bit Score: 144.00  E-value: 2.54e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176269710 126 ERREVIRKTWGQERTVAGVHIRRVFLSGVAANAreARKLNGLLAMEAAEHRDILQWGFQDSFFNLTLKQSLFHAWLDARC 205
Cdd:pfam01762   1 ARRNAIRKTWMNQGNSEGGRIKSLFLVGLSADT--DGKVADLVMEEAKLYGDIVVVDFEDTYENLTFKTLTGLLWAVSKC 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176269710 206 PGVRFVLNGDDDVFAHTDNMVHYLLGVPGAGDRHLFVGHLISHVGPIREKWSKYYVPELVTASKSYPPYCGGGGLLMSGF 285
Cdd:pfam01762  79 PSAKYIGKIDDDVYFFPDKLLSLLDNGNIDPSESSFYGYVMEEGPVIRNKKSKWYVSPSDYKCSRYPPYASGPFYVLSRD 158

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1176269710 286 TSRAIYQASLDLELFPIDDVYLGMCLQKAGLAP 318
Cdd:pfam01762 159 AAEKLLKASKHRRFLQIEDVYVGILANDLGISR 191
PLN03133 PLN03133
beta-1,3-galactosyltransferase; Provisional
 114-375 2.26e-11

beta-1,3-galactosyltransferase; Provisional


Pssm-ID: 215596 [Multi-domain]  Cd Length: 636  Bit Score: 65.21  E-value: 2.26e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176269710 114 LLLAIKSSPGNYERREVIRKTWGQERTV--AGVHIRrvFLSGVAANareaRKLNGLLAMEAAEHRDILQWGFQDsFFNLT 191
Cdd:PLN03133  387 LFIGVFSTANNFKRRMAVRRTWMQYDAVrsGAVAVR--FFVGLHKN----QMVNEELWNEARTYGDIQLMPFVD-YYSLI 459

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176269710 192 LKQSLFHAWLDARCPGVRFVLNGDDDVFAHTDNMvhyLLGVPGAGDRH-LFVGHLISHVGPIREKWSKYYVPELVTASKS 270
Cdd:PLN03133  460 TWKTLAICIFGTEVVSAKYVMKTDDDAFVRVDEV---LASLKRTNVSHgLLYGLINSDSQPHRNPDSKWYISPEEWPEET 536

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176269710 271 YPPYCGGGGLLMSGFTSRAIYQ--ASLDLELFPIDDVYLGMC---LQKAGLAPA--AHGGIRMVGVRvpsstlDSFDPCY 343
Cdd:PLN03133  537 YPPWAHGPGYVVSRDIAKEVYKrhKEGRLKMFKLEDVAMGIWiaeMKKEGLEVKyeNDGRIYNEGCK------DGYVVAH 610

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1176269710 344 YKElllvhrfvPYEMLLMWRAVHQ--QGLVCGKK 375
Cdd:PLN03133  611 YQS--------PREMLCLWQKLQEgkRATCCGEW 636
 
Name Accession Description Interval E-value
Galactosyl_T pfam01762
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
 126-318 2.54e-41

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


Pssm-ID: 426415 [Multi-domain]  Cd Length: 195  Bit Score: 144.00  E-value: 2.54e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176269710 126 ERREVIRKTWGQERTVAGVHIRRVFLSGVAANAreARKLNGLLAMEAAEHRDILQWGFQDSFFNLTLKQSLFHAWLDARC 205
Cdd:pfam01762   1 ARRNAIRKTWMNQGNSEGGRIKSLFLVGLSADT--DGKVADLVMEEAKLYGDIVVVDFEDTYENLTFKTLTGLLWAVSKC 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176269710 206 PGVRFVLNGDDDVFAHTDNMVHYLLGVPGAGDRHLFVGHLISHVGPIREKWSKYYVPELVTASKSYPPYCGGGGLLMSGF 285
Cdd:pfam01762  79 PSAKYIGKIDDDVYFFPDKLLSLLDNGNIDPSESSFYGYVMEEGPVIRNKKSKWYVSPSDYKCSRYPPYASGPFYVLSRD 158

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1176269710 286 TSRAIYQASLDLELFPIDDVYLGMCLQKAGLAP 318
Cdd:pfam01762 159 AAEKLLKASKHRRFLQIEDVYVGILANDLGISR 191
PLN03133 PLN03133
beta-1,3-galactosyltransferase; Provisional
 114-375 2.26e-11

beta-1,3-galactosyltransferase; Provisional


Pssm-ID: 215596 [Multi-domain]  Cd Length: 636  Bit Score: 65.21  E-value: 2.26e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176269710 114 LLLAIKSSPGNYERREVIRKTWGQERTV--AGVHIRrvFLSGVAANareaRKLNGLLAMEAAEHRDILQWGFQDsFFNLT 191
Cdd:PLN03133  387 LFIGVFSTANNFKRRMAVRRTWMQYDAVrsGAVAVR--FFVGLHKN----QMVNEELWNEARTYGDIQLMPFVD-YYSLI 459

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176269710 192 LKQSLFHAWLDARCPGVRFVLNGDDDVFAHTDNMvhyLLGVPGAGDRH-LFVGHLISHVGPIREKWSKYYVPELVTASKS 270
Cdd:PLN03133  460 TWKTLAICIFGTEVVSAKYVMKTDDDAFVRVDEV---LASLKRTNVSHgLLYGLINSDSQPHRNPDSKWYISPEEWPEET 536

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176269710 271 YPPYCGGGGLLMSGFTSRAIYQ--ASLDLELFPIDDVYLGMC---LQKAGLAPA--AHGGIRMVGVRvpsstlDSFDPCY 343
Cdd:PLN03133  537 YPPWAHGPGYVVSRDIAKEVYKrhKEGRLKMFKLEDVAMGIWiaeMKKEGLEVKyeNDGRIYNEGCK------DGYVVAH 610

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1176269710 344 YKElllvhrfvPYEMLLMWRAVHQ--QGLVCGKK 375
Cdd:PLN03133  611 YQS--------PREMLCLWQKLQEgkRATCCGEW 636
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH