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Conserved domains on  [gi|1176266313|ref|XP_020633071|]
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decorin [Pogona vitticeps]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 12183199)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

CATH:  3.80.10.10
Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
81-302 1.24e-17

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 83.44  E-value: 1.24e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  81 TTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKiskispgAFAPLKKLERLYLSKNNLKELPEnmpkslqelrahenei 160
Cdd:COG4886    74 LLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPE---------------- 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 161 tklrkvvfsglnnmivvelgtnplkssgiengAFQGMKKLSYIRISDTNITSIPKGLP--TSLTELHLDGNKINKLDAdS 238
Cdd:COG4886   131 --------------------------------ELANLTNLKELDLSNNQLTDLPEPLGnlTNLKSLDLSNNQLTDLPE-E 177

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1176266313 239 LNGLVHLAKLGLSHNNIASVDNgSLANTPLLRELHLNNNELSKVPSGLGEHKYIQVVYLHNNKI 302
Cdd:COG4886   178 LGNLTNLKELDLSNNQITDLPE-PLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQL 240
LRRNT smart00013
Leucine rich repeat N-terminal domain;
52-83 8.83e-12

Leucine rich repeat N-terminal domain;


:

Pssm-ID: 214470 [Multi-domain]  Cd Length: 33  Bit Score: 58.87  E-value: 8.83e-12
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1176266313   52 CPFGCQCYLRVVQCSDLGLTKVPRDLPSDTTL 83
Cdd:smart00013   2 CPAPCNCSGTAVDCSGRGLTEVPLDLPPDTTL 33
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
81-302 1.24e-17

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 83.44  E-value: 1.24e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  81 TTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKiskispgAFAPLKKLERLYLSKNNLKELPEnmpkslqelrahenei 160
Cdd:COG4886    74 LLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPE---------------- 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 161 tklrkvvfsglnnmivvelgtnplkssgiengAFQGMKKLSYIRISDTNITSIPKGLP--TSLTELHLDGNKINKLDAdS 238
Cdd:COG4886   131 --------------------------------ELANLTNLKELDLSNNQLTDLPEPLGnlTNLKSLDLSNNQLTDLPE-E 177

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1176266313 239 LNGLVHLAKLGLSHNNIASVDNgSLANTPLLRELHLNNNELSKVPSGLGEHKYIQVVYLHNNKI 302
Cdd:COG4886   178 LGNLTNLKELDLSNNQITDLPE-PLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQL 240
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
68-323 1.80e-15

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 77.81  E-value: 1.80e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  68 LGLTKVPRDLPSDTTLLDLQNNKITEIKDgdfknlkNLHALIlvnnkiskispgafaplkklERLYLSKNNLKELPENMP 147
Cdd:PRK15370  188 LGLTTIPACIPEQITTLILDNNELKSLPE-------NLQGNI--------------------KTLYANSNQLTSIPATLP 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 148 KSLQELRAHENEITKLRKVVFSGLNNMIVVELGTNPLKSSGIEngafqgmkKLSYIRISDTNITSIPKGLPTSLTELHLD 227
Cdd:PRK15370  241 DTIQEMELSINRITELPERLPSALQSLDLFHNKISCLPENLPE--------ELRYLSVYDNSIRTLPAHLPSGITHLNVQ 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 228 GNKINKLDADSLNGLvhlaKLGLSHNNIASVDNGSLAntPLLRELHLNNNELSKVPSGLGehKYIQVVYLHNNKIAAVGP 307
Cdd:PRK15370  313 SNSLTALPETLPPGL----KTLEAGENALTSLPASLP--PELQVLDVSKNQITVLPETLP--PTITTLDVSRNALTNLPE 384

                         250
                  ....*....|....*.
gi 1176266313 308 NdfCPPGYNTKKASYS 323
Cdd:PRK15370  385 N--LPAALQIMQASRN 398
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 82-283 2.54e-15

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 74.05  E-value: 2.54e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  82 TLLDLQNNKITEIkdGDFKNLKNLHALILVNNKISKISpgAFAPLKKLERLYLSKNNLKELP--ENMPKsLQELRAHENE 159
Cdd:cd21340     5 THLYLNDKNITKI--DNLSLCKNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIEnlENLVN-LKKLYLGGNR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 160 ITKLrkvvfSGLNNMivvelgtNPLKSSGIENgafQGMKKLSYIRISDTNITSIPKglptSLTELHLDGNKINklDADSL 239
Cdd:cd21340    80 ISVV-----EGLENL-------TNLEELHIEN---QRLPPGEKLTFDPRSLAALSN----SLRVLNISGNNID--SLEPL 138

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1176266313 240 NGLVHLAKLGLSHNNIASVDN--GSLANTPLLRELHLNNNELSKVP 283
Cdd:cd21340   139 APLRNLEQLDASNNQISDLEEllDLLSSWPSLRELDLTGNPVCKKP 184
LRR_8 pfam13855
Leucine rich repeat;
82-139 5.55e-12

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 60.23  E-value: 5.55e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1176266313  82 TLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKISPGAFAPLKKLERLYLSKNNL 139
Cdd:pfam13855   4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRRNT smart00013
Leucine rich repeat N-terminal domain;
52-83 8.83e-12

Leucine rich repeat N-terminal domain;


Pssm-ID: 214470 [Multi-domain]  Cd Length: 33  Bit Score: 58.87  E-value: 8.83e-12
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1176266313   52 CPFGCQCYLRVVQCSDLGLTKVPRDLPSDTTL 83
Cdd:smart00013   2 CPAPCNCSGTAVDCSGRGLTEVPLDLPPDTTL 33
LRRNT pfam01462
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 52-78 1.51e-09

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 396168 [Multi-domain]  Cd Length: 28  Bit Score: 52.63  E-value: 1.51e-09
                          10        20
                  ....*....|....*....|....*..
gi 1176266313  52 CPFGCQCYLRVVQCSDLGLTKVPRDLP 78
Cdd:pfam01462   2 CPVPCHCSATVVNCSDRGLTAVPRDLP 28
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
81-302 1.24e-17

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 83.44  E-value: 1.24e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  81 TTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKiskispgAFAPLKKLERLYLSKNNLKELPEnmpkslqelrahenei 160
Cdd:COG4886    74 LLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPE---------------- 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 161 tklrkvvfsglnnmivvelgtnplkssgiengAFQGMKKLSYIRISDTNITSIPKGLP--TSLTELHLDGNKINKLDAdS 238
Cdd:COG4886   131 --------------------------------ELANLTNLKELDLSNNQLTDLPEPLGnlTNLKSLDLSNNQLTDLPE-E 177

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1176266313 239 LNGLVHLAKLGLSHNNIASVDNgSLANTPLLRELHLNNNELSKVPSGLGEHKYIQVVYLHNNKI 302
Cdd:COG4886   178 LGNLTNLKELDLSNNQITDLPE-PLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQL 240
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
86-302 1.27e-16

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 80.36  E-value: 1.27e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  86 LQNNKITEIKDGDFKNLKNLHALILVNNKISKISPGAFAPLKKLERLYLSKNNLKELPENMPKSLQELRAHENEITKLRK 165
Cdd:COG4886     1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 166 VVFSGLNNMIVVELGTNPLKSSGIENGAFQGMKKLSYIRISDTNITSIPKGLP--TSLTELHLDGNKINKLDaDSLNGLV 243
Cdd:COG4886    81 LLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDLPEELAnlTNLKELDLSNNQLTDLP-EPLGNLT 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1176266313 244 HLAKLGLSHNNIASVDNgSLANTPLLRELHLNNNELSKVPSGLGEHKYIQVVYLHNNKI 302
Cdd:COG4886   160 NLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQL 217
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
60-293 5.64e-16

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 78.44  E-value: 5.64e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  60 LRVVQCSDLGLTKVPRDLPSDTTL--LDLQNNKITEIKDgDFKNLKNLHALILVNNKISKIsPGAFAPLKKLERLYLSKN 137
Cdd:COG4886   161 LKSLDLSNNQLTDLPEELGNLTNLkeLDLSNNQITDLPE-PLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNN 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 138 NLKELPE--NMPKsLQELRAHENEITKLRKvvFSGLNNMIVVELGTNPLKSSGIEN-GAFQGMKKLSYIRISDTNITSIP 214
Cdd:COG4886   239 QLTDLPElgNLTN-LEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKElELLLGLNSLLLLLLLLNLLELLI 315

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1176266313 215 KGLPTSLTELHLDGNKINKLDADSLNGLVHLAKLGLSHNNIASVDNGSLANTPLLRELHLNNNELSKVPSGLGEHKYIQ 293
Cdd:COG4886   316 LLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLL 394
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
68-323 1.80e-15

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 77.81  E-value: 1.80e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  68 LGLTKVPRDLPSDTTLLDLQNNKITEIKDgdfknlkNLHALIlvnnkiskispgafaplkklERLYLSKNNLKELPENMP 147
Cdd:PRK15370  188 LGLTTIPACIPEQITTLILDNNELKSLPE-------NLQGNI--------------------KTLYANSNQLTSIPATLP 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 148 KSLQELRAHENEITKLRKVVFSGLNNMIVVELGTNPLKSSGIEngafqgmkKLSYIRISDTNITSIPKGLPTSLTELHLD 227
Cdd:PRK15370  241 DTIQEMELSINRITELPERLPSALQSLDLFHNKISCLPENLPE--------ELRYLSVYDNSIRTLPAHLPSGITHLNVQ 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 228 GNKINKLDADSLNGLvhlaKLGLSHNNIASVDNGSLAntPLLRELHLNNNELSKVPSGLGehKYIQVVYLHNNKIAAVGP 307
Cdd:PRK15370  313 SNSLTALPETLPPGL----KTLEAGENALTSLPASLP--PELQVLDVSKNQITVLPETLP--PTITTLDVSRNALTNLPE 384

                         250
                  ....*....|....*.
gi 1176266313 308 NdfCPPGYNTKKASYS 323
Cdd:PRK15370  385 N--LPAALQIMQASRN 398
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 82-283 2.54e-15

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 74.05  E-value: 2.54e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  82 TLLDLQNNKITEIkdGDFKNLKNLHALILVNNKISKISpgAFAPLKKLERLYLSKNNLKELP--ENMPKsLQELRAHENE 159
Cdd:cd21340     5 THLYLNDKNITKI--DNLSLCKNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIEnlENLVN-LKKLYLGGNR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 160 ITKLrkvvfSGLNNMivvelgtNPLKSSGIENgafQGMKKLSYIRISDTNITSIPKglptSLTELHLDGNKINklDADSL 239
Cdd:cd21340    80 ISVV-----EGLENL-------TNLEELHIEN---QRLPPGEKLTFDPRSLAALSN----SLRVLNISGNNID--SLEPL 138

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1176266313 240 NGLVHLAKLGLSHNNIASVDN--GSLANTPLLRELHLNNNELSKVP 283
Cdd:cd21340   139 APLRNLEQLDASNNQISDLEEllDLLSSWPSLRELDLTGNPVCKKP 184
LRR_8 pfam13855
Leucine rich repeat;
82-139 5.55e-12

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 60.23  E-value: 5.55e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1176266313  82 TLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKISPGAFAPLKKLERLYLSKNNL 139
Cdd:pfam13855   4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRRNT smart00013
Leucine rich repeat N-terminal domain;
52-83 8.83e-12

Leucine rich repeat N-terminal domain;


Pssm-ID: 214470 [Multi-domain]  Cd Length: 33  Bit Score: 58.87  E-value: 8.83e-12
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1176266313   52 CPFGCQCYLRVVQCSDLGLTKVPRDLPSDTTL 83
Cdd:smart00013   2 CPAPCNCSGTAVDCSGRGLTEVPLDLPPDTTL 33
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 126-279 1.13e-11

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 63.65  E-value: 1.13e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 126 LKKLERLYLSKNNLKELPE-NMPKSLQELRAHENEITKLRkvvfsGLNNMivvelgtnplkssgiengafqgmkklsyir 204
Cdd:cd21340     1 LKRITHLYLNDKNITKIDNlSLCKNLKVLYLYDNKITKIE-----NLEFL------------------------------ 45

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1176266313 205 isdtnitsipkglpTSLTELHLDGNKINKLDadSLNGLVHLAKLGLSHNNIASVDNgsLANTPLLRELHLNNNEL 279
Cdd:cd21340    46 --------------TNLTHLYLQNNQIEKIE--NLENLVNLKKLYLGGNRISVVEG--LENLTNLEELHIENQRL 102
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
60-279 1.39e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 65.34  E-value: 1.39e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  60 LRVVQCSDLGLTKVPRDLPSDTTL--LDLQNNKITEIkDGDFKNLKNLHALILVNNKISKISpgAFAPLKKLERLYLSKN 137
Cdd:COG4886   184 LKELDLSNNQITDLPEPLGNLTNLeeLDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTDLP--ELGNLTNLEELDLSNN 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 138 NLKELPENMP-KSLQELRAHENEITKLRKVVFSGLNNMIVVELGTNPLKssgiENGAFQGMKKLSYIRISDTNITSIPKG 216
Cdd:COG4886   261 QLTDLPPLANlTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLN----LLELLILLLLLTTLLLLLLLLKGLLVT 336

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1176266313 217 LPTSLTELHLDGNKINKLDADSLNGLVHLAKLGLSHNNIASVDNGSLANTPLLRELHLNNNEL 279
Cdd:COG4886   337 LTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAG 399
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 73-299 3.27e-11

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 64.87  E-value: 3.27e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  73 VPRDL--PSDTTLLDLQNNKIT-EIKDGdFKNLKNLHALILVNNKISKISPGAFAPLKKLERLYLSKNNLK-ELPEnmpk 148
Cdd:PLN00113  348 IPKNLgkHNNLTVLDLSTNNLTgEIPEG-LCSSGNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSgELPS---- 422

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 149 slqelrahenEITKLRKVVFSGL-NNMIVVELGTNPLKSSGIE------NGAFQGM------KKLSYIRISDTNIT-SIP 214
Cdd:PLN00113  423 ----------EFTKLPLVYFLDIsNNNLQGRINSRKWDMPSLQmlslarNKFFGGLpdsfgsKRLENLDLSRNQFSgAVP 492

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 215 KGLPT--SLTELHLDGNKINKLDADSLNGLVHLAKLGLSHNNIASVDNGSLANTPLLRELHLNNNELS-KVPSGLG-EHK 290
Cdd:PLN00113  493 RKLGSlsELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSgEIPKNLGnVES 572


                  ....*....
gi 1176266313 291 YIQVVYLHN 299
Cdd:PLN00113  573 LVQVNISHN 581
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
60-191 4.73e-10

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 60.87  E-value: 4.73e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  60 LRVVQCSDLGLTKVPRDLPSDTTLLDLQNNKITEIKDGDFKNLKNLHA------------------LILVNNKISkISPG 121
Cdd:PRK15370  285 LRYLSVYDNSIRTLPAHLPSGITHLNVQSNSLTALPETLPPGLKTLEAgenaltslpaslppelqvLDVSKNQIT-VLPE 363

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1176266313 122 AFAPlkKLERLYLSKNNLKELPENMPKSLQELRAHENEITKLRKVVFSGLNN-----MIVVElgTNPLKSSGIEN 191
Cdd:PRK15370  364 TLPP--TITTLDVSRNALTNLPENLPAALQIMQASRNNLVRLPESLPHFRGEgpqptRIIVE--YNPFSERTIQN 434
LRR_8 pfam13855
Leucine rich repeat;
219-279 4.90e-10

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 54.84  E-value: 4.90e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1176266313 219 TSLTELHLDGNKINKLDADSLNGLVHLAKLGLSHNNIASVDNGSLANTPLLRELHLNNNEL 279
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
70-234 9.55e-10

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 60.10  E-value: 9.55e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  70 LTKVPRDLPSDTTLLDLQNNKITEIKDgdfKNLKNLHALILVNNKISKIsPGAFAplKKLERLYLSKNNLKELPENMPKS 149
Cdd:PRK15370  232 LTSIPATLPDTIQEMELSINRITELPE---RLPSALQSLDLFHNKISCL-PENLP--EELRYLSVYDNSIRTLPAHLPSG 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 150 LQELRAHENEITKLRKVVFSGLNNMIVVE--LGTNP------LKSSGIENGAFQGMKK-----LSYIRISDTNITSIPKG 216
Cdd:PRK15370  306 ITHLNVQSNSLTALPETLPPGLKTLEAGEnaLTSLPaslppeLQVLDVSKNQITVLPEtlpptITTLDVSRNALTNLPEN 385

                         170
                  ....*....|....*...
gi 1176266313 217 LPTSLTELHLDGNKINKL 234
Cdd:PRK15370  386 LPAALQIMQASRNNLVRL 403
LRRNT pfam01462
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 52-78 1.51e-09

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 396168 [Multi-domain]  Cd Length: 28  Bit Score: 52.63  E-value: 1.51e-09
                          10        20
                  ....*....|....*....|....*..
gi 1176266313  52 CPFGCQCYLRVVQCSDLGLTKVPRDLP 78
Cdd:pfam01462   2 CPVPCHCSATVVNCSDRGLTAVPRDLP 28
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 82-281 3.32e-08

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 54.28  E-value: 3.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  82 TLLDLQNNKITEIKDGDFKNL---KNLHALILVNNKIS----KISPGAFAPLK-KLERLYLSKNNLKElpENMPKSLQEL 153
Cdd:cd00116    84 QELDLSDNALGPDGCGVLESLlrsSSLQELKLNNNGLGdrglRLLAKGLKDLPpALEKLVLGRNRLEG--ASCEALAKAL 161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 154 RAHeneiTKLRKVvfsglnnmivvELGTNPLKSSGIENgAFQGMK---KLSYIRISDTNITS-----IPKGLPT--SLTE 223
Cdd:cd00116   162 RAN----RDLKEL-----------NLANNGIGDAGIRA-LAEGLKancNLEVLDLNNNGLTDegasaLAETLASlkSLEV 225

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1176266313 224 LHLDGNKIN-----KLDADSLNGLVHLAKLGLSHNNIASVDNGSLA----NTPLLRELHLNNNELSK 281
Cdd:cd00116   226 LNLGDNNLTdagaaALASALLSPNISLLTLSLSCNDITDDGAKDLAevlaEKESLLELDLRGNKFGE 292
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 73-310 8.85e-08

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 54.08  E-value: 8.85e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  73 VPRDLPSDTTL--LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKISPGAFAPLKKLERLYLSKNNLK-ELPENMP-- 147
Cdd:PLN00113  228 IPYEIGGLTSLnhLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSgEIPELVIql 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 148 KSLQELRAHENEITKLRKVVFSGLNNMIVVELGTNPLkSSGIENGaFQGMKKLSYIRISDTNITS-IPKGLPTS--LTEL 224
Cdd:PLN00113  308 QNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKF-SGEIPKN-LGKHNNLTVLDLSTNNLTGeIPEGLCSSgnLFKL 385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 225 HLDGNKINKLDADSLNGLVHLAKLGLSHNNIASVDNGSLANTPLLRELHLNNNELS-KVPSGLGEHKYIQVVYLHNNKIA 303
Cdd:PLN00113  386 ILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQgRINSRKWDMPSLQMLSLARNKFF 465


                  ....*..
gi 1176266313 304 AVGPNDF 310
Cdd:PLN00113  466 GGLPDSF 472
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 72-344 1.05e-07

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 53.70  E-value: 1.05e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  72 KVPRDLPSDTTL--LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKISPGAFAPLKKLERLYLSKNNLK-ELPenmpk 148
Cdd:PLN00113  155 EIPNDIGSFSSLkvLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSgEIP----- 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 149 slqelraheNEITKLrkvvfSGLNNM-IVVELGTNPLKSSgiengaFQGMKKLSYIRISDTNIT-SIPKGL--PTSLTEL 224
Cdd:PLN00113  230 ---------YEIGGL-----TSLNHLdLVYNNLTGPIPSS------LGNLKNLQYLFLYQNKLSgPIPPSIfsLQKLISL 289

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 225 HLDGNKINKLDADSLNGLVHLAKLGLSHNNIASVDNGSLANTPLLRELHLNNNELS-KVPSGLGEHKYIQVVYLHNNKIA 303
Cdd:PLN00113  290 DLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSgEIPKNLGKHNNLTVLDLSTNNLT 369

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1176266313 304 AVGPNDFCPPGYNTKkasysgVSLFSNPVQyWEIQPSSFRC 344
Cdd:PLN00113  370 GEIPEGLCSSGNLFK------LILFSNSLE-GEIPKSLGAC 403
LRR_8 pfam13855
Leucine rich repeat;
104-160 3.27e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 46.75  E-value: 3.27e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 104 NLHALILVNNKISKISPGAFAPLKKLERLYLSKNNLKELPENM---PKSLQELRAHENEI 160
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAfsgLPSLRYLDLSGNRL 61
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 59-255 9.15e-07

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 50.17  E-value: 9.15e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  59 YLRVVQCSDLGLTKVPRDLPSDTTL--LDLQNNKITE------IKDGdfKNLKNLHALILVNNKISKISPGAFAPL---- 126
Cdd:COG5238   186 YLGCNQIGDEGIEELAEALTQNTTVttLWLKRNPIGDegaeilAEAL--KGNKSLTTLDLSNNQIGDEGVIALAEAlknn 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 127 KKLERLYLSKNNLKE-----LPENM--PKSLQELRAHENEITKLRKVVFS-GL-NNMIVVELGtnpLKSSGIENgafQGM 197
Cdd:COG5238   264 TTVETLYLSGNQIGAegaiaLAKALqgNTTLTSLDLSVNRIGDEGAIALAeGLqGNKTLHTLN---LAYNGIGA---QGA 337

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1176266313 198 K---------------KLSYIRISDTNITSIPKGL--PTSLTELHLDGNKINKLDADSLN-GLVH--LAKLGLSHNNI 255
Cdd:COG5238   338 IalakalqenttlhslDLSDNQIGDEGAIALAKYLegNTTLRELNLGKNNIGKQGAEALIdALQTnrLHTLILDGNLI 415
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 29-161 1.35e-06

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 49.28  E-value: 1.35e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  29 LEDEPGSGTPEPTVPTGY--PPMSVCPFGC-QCYLRVVQCSDLGLTkvprdLPSDTTL--LDLQNNKITEikDG------ 97
Cdd:cd00116   115 LNNNGLGDRGLRLLAKGLkdLPPALEKLVLgRNRLEGASCEALAKA-----LRANRDLkeLNLANNGIGD--AGiralae 187

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1176266313  98 DFKNLKNLHALILVNNKI----SKISPGAFAPLKKLERLYLSKNNLK-----ELPENMPK---SLQELRAHENEIT 161
Cdd:cd00116   188 GLKANCNLEVLDLNNNGLtdegASALAETLASLKSLEVLNLGDNNLTdagaaALASALLSpniSLLTLSLSCNDIT 263
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 219-305 2.17e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 45.16  E-value: 2.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 219 TSLTELHLDGNKINKLDAdsLNGLVHLAKLGLSHNNIASVDNgsLANTPLLRELHLNNNELSKVPsGLGEHKYIQVVYLH 298
Cdd:cd21340     2 KRITHLYLNDKNITKIDN--LSLCKNLKVLYLYDNKITKIEN--LEFLTNLTHLYLQNNQIEKIE-NLENLVNLKKLYLG 76


                  ....*..
gi 1176266313 299 NNKIAAV 305
Cdd:cd21340    77 GNRISVV 83
LRR_9 pfam14580
Leucine-rich repeat;
84-162 3.10e-05

Leucine-rich repeat;


Pssm-ID: 405295 [Multi-domain]  Cd Length: 175  Bit Score: 43.98  E-value: 3.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  84 LDLQNNKITEIkDGdFKNLKNLHALILVNNKISKISPGAFAPLKKLERLYLSKNNLKELPENMP----KSLQELRAHENE 159
Cdd:pfam14580  47 IDFSDNEIRKL-DG-FPLLRRLKTLLLNNNRICRIGEGLGEALPNLTELILTNNNLQELGDLDPlaslKKLTFLSLLRNP 124


                  ...
gi 1176266313 160 ITK 162
Cdd:pfam14580 125 VTN 127
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 82-165 5.67e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 43.62  E-value: 5.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  82 TLLDLQNNKITEIkdGDFKNLKNLHALILVNNKISKI------------------------------------------- 118
Cdd:cd21340    49 THLYLQNNQIEKI--ENLENLVNLKKLYLGGNRISVVeglenltnleelhienqrlppgekltfdprslaalsnslrvln 126

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 119 -------SPGAFAPLKKLERLYLSKNNLKELPE------NMPkSLQELRAHENEITKLRK 165
Cdd:cd21340   127 isgnnidSLEPLAPLRNLEQLDASNNQISDLEElldllsSWP-SLRELDLTGNPVCKKPK 185
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
62-286 1.21e-04

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 44.00  E-value: 1.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313  62 VVQCSDLGLTKVPRDLPSDTTLLDLQNNKITEIKDGDfknlKNLHALILVNNKISK---ISPGAFA------PLKKLE-- 130
Cdd:PRK15387  205 VLNVGESGLTTLPDCLPAHITTLVIPDNNLTSLPALP----PELRTLEVSGNQLTSlpvLPPGLLElsifsnPLTHLPal 280

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 131 -----RLYLSKNNLKELPEnMPKSLQELRAHENEITKLRKV-----VFSGLNNMIvVELGTNPlkssgiengafQGMKKL 200
Cdd:PRK15387  281 psglcKLWIFGNQLTSLPV-LPPGLQELSVSDNQLASLPALpselcKLWAYNNQL-TSLPTLP-----------SGLQEL 347

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 201 SyirISDTNITSIPKgLPTSLTELHLDGNKINKLDADSLNglvhLAKLGLSHNNIAsvdngSLANTPL-LRELHLNNNEL 279
Cdd:PRK15387  348 S---VSDNQLASLPT-LPSELYKLWAYNNRLTSLPALPSG----LKELIVSGNRLT-----SLPVLPSeLKELMVSGNRL 414

                         250
                  ....*....|
gi 1176266313 280 SK---VPSGL 286
Cdd:PRK15387  415 TSlpmLPSGL 424
LRR_8 pfam13855
Leucine rich repeat;
244-302 1.29e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.43  E-value: 1.29e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 244 HLAKLGLSHNNIASVDNGSLANTPLLRELHLNNNELSKVPSGLGEH-KYIQVVYLHNNKI 302
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGlPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
187-231 9.07e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.12  E-value: 9.07e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1176266313 187 SGIENGAFQGMKKLSYIRISDTNITSIPK----GLPtSLTELHLDGNKI 231
Cdd:pfam13855  14 TSLDDGAFKGLSNLKVLDLSNNLLTTLSPgafsGLP-SLRYLDLSGNRL 61
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 103-139 1.33e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 36.07  E-value: 1.33e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1176266313 103 KNLHALILVNNKISKISPgaFAPLKKLERLYLSKNNL 139
Cdd:pfam12799   1 PNLEVLDLSNNQITDIPP--LAKLPNLETLDLSGNNK 35
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
205-307 1.49e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 40.30  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176266313 205 ISDTNITSIPKGLPTSLTELHLDGNKINKLDADSLNGLVHLAKLGLSHNNiasvdngSLANTPLLRELHLNNNELSKVPS 284
Cdd:COG4886    58 RDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPE 130

                          90       100
                  ....*....|....*....|...
gi 1176266313 285 GLGEHKYIQVVYLHNNKIAAVGP 307
Cdd:COG4886   131 ELANLTNLKELDLSNNQLTDLPE 153
PLN03150 PLN03150
hypothetical protein; Provisional
 221-287 2.68e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 39.80  E-value: 2.68e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1176266313 221 LTELHLDGNKINKLDADSLNGLVHLAKLGLSHNNIASVDNGSLANTPLLRELHLNNNELS-KVPSGLG 287
Cdd:PLN03150  444 LQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSgRVPAALG 511
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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