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Conserved domains on  [gi|1121973574|ref|XP_019471806|]
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dnaJ homolog subfamily B member 6 isoform X3 [Meleagris gallopavo]

Protein Classification

J domain-containing protein( domain architecture ID 1001220)

J domain-containing protein similar to molecular chaperone DnaJ, part of the DnaK-DnaJ-GrpE system, prevents the aggregation of unfolded substrate and acts primarily by stimulating the ATPase activity of Hsp70

CATH:  1.10.287.110
Gene Ontology:  GO:0006457
PubMed:  9644977|8016869|15170475
SCOP:  4000605

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DnaJ_bact super family cl37091
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 3-106 1.71e-41

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


The actual alignment was detected with superfamily member TIGR02349:

Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 143.90  E-value: 1.71e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPEnkEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGGSH 82
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNKD--KEAEEKFKEINEAYEVLSDPEKRAQYDQFGHAGFNGGGGGGGG 78

                          90       100
                  ....*....|....*....|....
gi 1121973574  83 HDNPFEFGFtFRNPNDVFREFFGG 106
Cdd:TIGR02349  79 GFNGFDIGF-FGDFGDIFGDFFGG 101
 
Name Accession Description Interval E-value
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 3-106 1.71e-41

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 143.90  E-value: 1.71e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPEnkEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGGSH 82
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNKD--KEAEEKFKEINEAYEVLSDPEKRAQYDQFGHAGFNGGGGGGGG 78

                          90       100
                  ....*....|....*....|....
gi 1121973574  83 HDNPFEFGFtFRNPNDVFREFFGG 106
Cdd:TIGR02349  79 GFNGFDIGF-FGDFGDIFGDFFGG 101
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 3-107 2.20e-40

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 141.05  E-value: 2.20e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKeEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLiNGGGGGSH 82
Cdd:PRK10767    5 DYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPGDK-EAEEKFKEIKEAYEVLSDPQKRAAYDQYGHAAF-EQGGGGGG 82

                          90       100
                  ....*....|....*....|....*
gi 1121973574  83 HDNPFEFGFTFrnpNDVFREFFGGR 107
Cdd:PRK10767   83 FGGGGGFGDIF---GDIFGDIFGGG 104
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 3-73 6.45e-38

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 128.28  E-value: 6.45e-38
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKeEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGL 73
Cdd:COG0484     1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGDP-EAEEKFKEINEAYEVLSDPEKRAAYDRFGHAAE 70
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 3-66 1.87e-37

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 124.51  E-value: 1.87e-37
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKeEAEQQFKQVAEAYEVLSDAKKRDIYD 66
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDP-EAEEKFKEINEAYEVLSDPEKRAIYD 63
DnaJ smart00271
DnaJ molecular chaperone homology domain;
2-61 2.96e-32

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 111.17  E-value: 2.96e-32
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574    2 VDYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKEEAEQQFKQVAEAYEVLSDAKK 61
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDKEEAEEKFKEINEAYEVLSDPEK 60
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
3-106 6.88e-30

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 114.53  E-value: 6.88e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPEnkEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLingggggsh 82
Cdd:NF037946    6 DYYEVLGVDRDADDQEIKKAFRKLAKKYHPDRNKA--PDAAEIFAEINEAYEVLSNPEKRANYDKYGHDGV--------- 74

                          90       100
                  ....*....|....*....|....
gi 1121973574  83 hDNPFEFGFtfrNPNDVFREFFGG 106
Cdd:NF037946   75 -DGEGGFGF---DAFDVFSSFFET 94
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 3-58 4.70e-29

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 103.01  E-value: 4.70e-29
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENkEEAEQQFKQVAEAYEVLSD 58
Cdd:cd06257     1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDD-PEAEEKFKEINEAYEVLSD 55
 
Name Accession Description Interval E-value
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 3-106 1.71e-41

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 143.90  E-value: 1.71e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPEnkEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGGSH 82
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNKD--KEAEEKFKEINEAYEVLSDPEKRAQYDQFGHAGFNGGGGGGGG 78

                          90       100
                  ....*....|....*....|....
gi 1121973574  83 HDNPFEFGFtFRNPNDVFREFFGG 106
Cdd:TIGR02349  79 GFNGFDIGF-FGDFGDIFGDFFGG 101
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 3-107 2.20e-40

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 141.05  E-value: 2.20e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKeEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLiNGGGGGSH 82
Cdd:PRK10767    5 DYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPGDK-EAEEKFKEIKEAYEVLSDPQKRAAYDQYGHAAF-EQGGGGGG 82

                          90       100
                  ....*....|....*....|....*
gi 1121973574  83 HDNPFEFGFTFrnpNDVFREFFGGR 107
Cdd:PRK10767   83 FGGGGGFGDIF---GDIFGDIFGGG 104
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 3-73 6.45e-38

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 128.28  E-value: 6.45e-38
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKeEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGL 73
Cdd:COG0484     1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGDP-EAEEKFKEINEAYEVLSDPEKRAAYDRFGHAAE 70
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 3-66 1.87e-37

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 124.51  E-value: 1.87e-37
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKeEAEQQFKQVAEAYEVLSDAKKRDIYD 66
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDP-EAEEKFKEINEAYEVLSDPEKRAIYD 63
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 3-105 1.22e-35

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 128.73  E-value: 1.22e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKeEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLING-GGGGS 81
Cdd:PRK14294    5 DYYEILGVTRDASEEEIKKSYRKLAMKYHPDRNPGDK-EAEELFKEAAEAYEVLSDPKKRGIYDQYGHEGLSGTgFSGFS 83

                          90       100
                  ....*....|....*....|....*
gi 1121973574  82 HHDNPF-EFGftfrnpnDVFREFFG 105
Cdd:PRK14294   84 GFDDIFsSFG-------DIFEDFFG 101
PRK14282 PRK14282
chaperone protein DnaJ; Provisional
 3-107 1.59e-33

chaperone protein DnaJ; Provisional


Pssm-ID: 184603 [Multi-domain]  Cd Length: 369  Bit Score: 122.98  E-value: 1.59e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGGSH 82
Cdd:PRK14282    5 DYYEILGVSRNATQEEIKRAYKRLVKEWHPDRHPENRKEAEQKFKEIQEAYEVLSDPQKRAMYDRFGYVGEQPPYQETES 84

                          90       100       110
                  ....*....|....*....|....*....|
gi 1121973574  83 HDNPFE-----FGFTFRnpNDVFREFFGGR 107
Cdd:PRK14282   85 GGGFFEdifkdFENIFN--RDIFDIFFGER 112
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
 3-105 7.92e-33

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 121.39  E-value: 7.92e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENkEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGGSH 82
Cdd:PRK14301    5 DYYEVLGVSRDASEDEIKKAYRKLALQYHPDRNPDN-PEAEQKFKEAAEAYEVLRDAEKRARYDRFGHAGVNGNGGFGGF 83

                          90       100
                  ....*....|....*....|...
gi 1121973574  83 HDNPFEFGfTFrnpNDVFREFFG 105
Cdd:PRK14301   84 SSAEDIFS-HF---SDIFGDLFG 102
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 3-106 2.71e-32

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 119.95  E-value: 2.71e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPEnkEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLingggggsh 82
Cdd:PRK14298    6 DYYEILGLSKDASVEDIKKAYRKLAMKYHPDKNKE--PDAEEKFKEISEAYAVLSDAEKRAQYDRFGHAGI--------- 74

                          90       100
                  ....*....|....*....|....*....
gi 1121973574  83 hDNPFEFGFTFRNPN-----DVFREFFGG 106
Cdd:PRK14298   75 -DNQYSAEDIFRGADfggfgDIFEMFFGG 102
DnaJ smart00271
DnaJ molecular chaperone homology domain;
2-61 2.96e-32

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 111.17  E-value: 2.96e-32
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574    2 VDYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKEEAEQQFKQVAEAYEVLSDAKK 61
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDKEEAEEKFKEINEAYEVLSDPEK 60
PRK14280 PRK14280
molecular chaperone DnaJ;
3-109 7.66e-32

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 118.67  E-value: 7.66e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPEnkEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGGSH 82
Cdd:PRK14280    5 DYYEVLGVSKSASKDEIKKAYRKLSKKYHPDINKE--EGADEKFKEISEAYEVLSDDQKRAQYDQFGHAGPNQGFGGGGF 82

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1121973574  83 HDNPFEFGFTFrnpNDVFREFFGG----RDP 109
Cdd:PRK14280   83 GGGDFGGGFGF---EDIFSSFFGGggrrRDP 110
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 3-106 9.86e-32

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 118.50  E-value: 9.86e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLiNGGGGGSH 82
Cdd:PRK14290    4 DYYKILGVDRNASQEDIKKAFRELAKKWHPDLHPGNKAEAEEKFKEISEAYEVLSDPQKRRQYDQTGTVDF-GAGGSNFN 82

                          90       100
                  ....*....|....*....|....*
gi 1121973574  83 HDNpfefgFT-FRNPNDVFREFFGG 106
Cdd:PRK14290   83 WDN-----FThFSDINDIFNQIFGG 102
PRK14289 PRK14289
molecular chaperone DnaJ;
3-106 3.13e-30

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 114.54  E-value: 3.13e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKeEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGGSH 82
Cdd:PRK14289    6 DYYEVLGVSKTATVDEIKKAYRKKAIQYHPDKNPGDK-EAEEKFKEAAEAYDVLSDPDKRSRYDQFGHAGVGGAAGGGGF 84

                          90       100
                  ....*....|....*....|....
gi 1121973574  83 HDNPFEFGFTFRNPNDVFREFFGG 106
Cdd:PRK14289   85 SGEGMSMEDIFSMFGDIFGGHGGG 108
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
3-106 6.88e-30

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 114.53  E-value: 6.88e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPEnkEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLingggggsh 82
Cdd:NF037946    6 DYYEVLGVDRDADDQEIKKAFRKLAKKYHPDRNKA--PDAAEIFAEINEAYEVLSNPEKRANYDKYGHDGV--------- 74

                          90       100
                  ....*....|....*....|....
gi 1121973574  83 hDNPFEFGFtfrNPNDVFREFFGG 106
Cdd:NF037946   75 -DGEGGFGF---DAFDVFSSFFET 94
PRK14284 PRK14284
chaperone protein DnaJ; Provisional
 3-105 8.24e-30

chaperone protein DnaJ; Provisional


Pssm-ID: 237658 [Multi-domain]  Cd Length: 391  Bit Score: 113.78  E-value: 8.24e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKeEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGGSh 82
Cdd:PRK14284    2 DYYTILGVSKTASPEEIKKAYRKLAVKYHPDKNPGDA-EAEKRFKEVSEAYEVLSDAQKRESYDRYGKDGPFAGAGGFG- 79

                          90       100
                  ....*....|....*....|...
gi 1121973574  83 hdnpfefGFTFRNPNDVFREFFG 105
Cdd:PRK14284   80 -------GAGMGNMEDALRTFMG 95
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 3-106 1.04e-29

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 113.36  E-value: 1.04e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKeEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLinGGGGGSH 82
Cdd:PRK14281    4 DYYEVLGVSRSADKDEIKKAYRKLALKYHPDKNPDNK-EAEEHFKEVNEAYEVLSNDDKRRRYDQFGHAGV--GSSAASG 80

                          90       100
                  ....*....|....*....|....*..
gi 1121973574  83 HDNPFEFGFTfrNPNDVFREF---FGG 106
Cdd:PRK14281   81 GGPGYGGGGG--DFNDIFSAFndmFGG 105
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 3-106 1.22e-29

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 112.94  E-value: 1.22e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPEnkEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGGSh 82
Cdd:PRK14291    4 DYYEILGVSRNATQEEIKKAYRRLARKYHPDFNKN--PEAEEKFKEINEAYQVLSDPEKRKLYDQFGHAAFSGSGQQQQ- 80

                          90       100
                  ....*....|....*....|....
gi 1121973574  83 hDNPFEFGFTFRNPNDVFREFFGG 106
Cdd:PRK14291   81 -GQEGFSDFGGGNIEDILEDVFDI 103
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 3-58 4.70e-29

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 103.01  E-value: 4.70e-29
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENkEEAEQQFKQVAEAYEVLSD 58
Cdd:cd06257     1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDD-PEAEEKFKEINEAYEVLSD 55
PRK14286 PRK14286
chaperone protein DnaJ; Provisional
 4-106 5.65e-29

chaperone protein DnaJ; Provisional


Pssm-ID: 172774 [Multi-domain]  Cd Length: 372  Bit Score: 111.23  E-value: 5.65e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   4 YYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKeEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGlINGGGGGSHH 83
Cdd:PRK14286    6 YYDILGVSKSANDEEIKSAYRKLAIKYHPDKNKGNK-ESEEKFKEATEAYEILRDPKKRQAYDQFGKAG-VNAGAGGFGQ 83

                          90       100
                  ....*....|....*....|...
gi 1121973574  84 DNPFEFGFTFRNPNDVFREFFGG 106
Cdd:PRK14286   84 GAYTDFSDIFGDFGDIFGDFFGG 106
SEC63 COG5407
Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular ...
 3-62 1.21e-28

Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 444165 [Multi-domain]  Cd Length: 61  Bit Score: 102.00  E-value: 1.21e-28
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKeEAEQQFKQVAEAYEVLSDAKKR 62
Cdd:COG5407     1 DPYEVLGVAKTASADEIKKAYRKLAKKYHPDRNKGDP-KAEERFKEINEAYELLSDAEKR 59
PRK14297 PRK14297
molecular chaperone DnaJ;
3-106 1.27e-28

molecular chaperone DnaJ;


Pssm-ID: 184611 [Multi-domain]  Cd Length: 380  Bit Score: 110.26  E-value: 1.27e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKeEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGGSH 82
Cdd:PRK14297    5 DYYEVLGLEKGASDDEIKKAFRKLAIKYHPDKNKGNK-EAEEKFKEINEAYQVLSDPQKKAQYDQFGTADFNGAGGFGSG 83

                          90       100
                  ....*....|....*....|....
gi 1121973574  83 HDNPFEFgFTFRNPNDVFREFFGG 106
Cdd:PRK14297   84 GFGGFDF-SDMGGFGDIFDSFFGG 106
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 1-106 1.50e-28

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 109.98  E-value: 1.50e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   1 MVDYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPEnkEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKE---GLINGG 77
Cdd:PRK14292    1 MMDYYELLGVSRTASADEIKSAYRKLALKYHPDRNKE--KGAAEKFAQINEAYAVLSDAEKRAHYDRFGTApgaGMPGGD 78

                          90       100
                  ....*....|....*....|....*....
gi 1121973574  78 GggshhdnpfeFGFTFRNPNDVFREFFGG 106
Cdd:PRK14292   79 P----------FGGMGFDPMDIFEQLFGG 97
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 3-106 2.25e-28

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 109.53  E-value: 2.25e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPEnkEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGGSH 82
Cdd:PRK14283    6 DYYEVLGVDRNADKKEIKKAYRKLARKYHPDVSEE--EGAEEKFKEISEAYAVLSDDEKRQRYDQFGHAGMDGFSQEDIF 83

                          90       100
                  ....*....|....*....|....*....
gi 1121973574  83 HDNPFE-----FGFTFRNPNDVFRefFGG 106
Cdd:PRK14283   84 NNINFEdifqgFGFGIGNIFDMFG--FGG 110
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 3-106 5.00e-28

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 108.60  E-value: 5.00e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPEnkEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGkeglingggggsh 82
Cdd:PRK14278    4 DYYGLLGVSRNASDAEIKRAYRKLARELHPDVNPD--EEAQEKFKEISVAYEVLSDPEKRRIVDLGG------------- 68

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1121973574  83 hdNPFE--------FGFTFRNPNDVFREFFGG 106
Cdd:PRK14278   69 --DPLEsaggggggFGGGFGGLGDVFEAFFGG 98
PRK14277 PRK14277
chaperone protein DnaJ; Provisional
 3-105 1.37e-27

chaperone protein DnaJ; Provisional


Pssm-ID: 184599 [Multi-domain]  Cd Length: 386  Bit Score: 107.58  E-value: 1.37e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKeEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLinggGGGSH 82
Cdd:PRK14277    6 DYYEILGVDRNATEEEIKKAYRRLAKKYHPDLNPGDK-EAEQKFKEINEAYEILSDPQKRAQYDQFGHAAF----DPGGF 80

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1121973574  83 HDNPFEFG--------FTFRNPNDVFREFFG 105
Cdd:PRK14277   81 GQGGFGQGgfggggfdFDFGGFGDIFEDIFG 111
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
1-67 1.48e-27

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 100.18  E-value: 1.48e-27
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1121973574   1 MVDYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKEEAEQQFKQVAEAYEVLSDAKKRDIYDR 67
Cdd:COG2214     4 LKDHYAVLGVPPDASLEEIRQAYRRLAKLLHPDRGGELKALAEELFQRLNEAYEVLSDPERRAEYDR 70
PRK14276 PRK14276
chaperone protein DnaJ; Provisional
 3-109 3.35e-27

chaperone protein DnaJ; Provisional


Pssm-ID: 237653 [Multi-domain]  Cd Length: 380  Bit Score: 106.33  E-value: 3.35e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPEnkEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGGSH 82
Cdd:PRK14276    5 EYYDRLGVSKDASQDEIKKAYRKLSKKYHPDINKE--PGAEEKYKEVQEAYETLSDPQKRAAYDQYGAAGANGGFGGGAG 82

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1121973574  83 HDNPFEFGFTFRNPNDVFREFFGG----RDP 109
Cdd:PRK14276   83 GFGGFDGSGGFGGFEDIFSSFFGGggarRNP 113
PRK14293 PRK14293
molecular chaperone DnaJ;
1-106 8.79e-26

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 102.38  E-value: 8.79e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   1 MVDYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPEnkEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGG 80
Cdd:PRK14293    2 AADYYEILGVSRDADKDELKRAYRRLARKYHPDVNKE--PGAEDRFKEINRAYEVLSDPETRARYDQFGEAGVSGAAGFP 79

                          90       100
                  ....*....|....*....|....*.
gi 1121973574  81 SHHDNPfefGFTfrnpnDVFREFFGG 106
Cdd:PRK14293   80 DMGDMG---GFA-----DIFETFFSG 97
PRK14285 PRK14285
chaperone protein DnaJ; Provisional
 3-107 6.13e-25

chaperone protein DnaJ; Provisional


Pssm-ID: 172773 [Multi-domain]  Cd Length: 365  Bit Score: 100.07  E-value: 6.13e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKeEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGGSH 82
Cdd:PRK14285    4 DYYEILGLSKGASKDEIKKAYRKIAIKYHPDKNKGNK-EAESIFKEATEAYEVLIDDNKRAQYDRFGHTAFEGGGGFEGF 82

                          90       100
                  ....*....|....*....|....*
gi 1121973574  83 HDNPFEFGFTFRNPNDVFREFFGGR 107
Cdd:PRK14285   83 SGGFSGFSDIFEDFGDIFDSFFTGN 107
PRK14279 PRK14279
molecular chaperone DnaJ;
3-68 2.11e-24

molecular chaperone DnaJ;


Pssm-ID: 237655 [Multi-domain]  Cd Length: 392  Bit Score: 99.04  E-value: 2.11e-24
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKeEAEQQFKQVAEAYEVLSDAKKRDIYDRF 68
Cdd:PRK14279   10 DFYKELGVSSDASAEEIKKAYRKLARELHPDANPGDP-AAEERFKAVSEAHDVLSDPAKRKEYDET 74
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 3-110 2.59e-24

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 97.32  E-value: 2.59e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPEnkEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGlINGGGGGSH 82
Cdd:PRK14299    5 DYYAILGVPKNASQDEIKKAFKKLARKYHPDVNKS--PGAEEKFKEINEAYTVLSDPEKRRIYDTYGTTA-ASAGWQGPP 81

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1121973574  83 HDNPFEFGFTFRNPND---VFREFFGGRDPF 110
Cdd:PRK14299   82 PGPPGGGDFSGFNVGDfsdFFQQLFGGRGGF 112
termin_org_DnaJ TIGR03835
terminal organelle assembly protein TopJ; This model describes TopJ (MG_200, CbpA), a DnaJ ...
 3-104 6.95e-23

terminal organelle assembly protein TopJ; This model describes TopJ (MG_200, CbpA), a DnaJ homolog and probable assembly protein of the Mycoplasma terminal organelle. The terminal organelle is involved in both cytadherence and gliding motility. [Cellular processes, Chemotaxis and motility]


Pssm-ID: 274808 [Multi-domain]  Cd Length: 871  Bit Score: 96.04  E-value: 6.95e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNpeNKEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINgggggsh 82
Cdd:TIGR03835   3 DYYEVLGIDRDADEQEIKKAFRKLAKKYHPDRN--KAPDAASIFAEINEANDVLSNPKKRANYDKYGHDGVDR------- 73

                          90       100
                  ....*....|....*....|..
gi 1121973574  83 hdnpfEFGFTFRnpNDVFREFF 104
Cdd:TIGR03835  74 -----EDDFDFQ--ADVFNSFF 88
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 4-106 1.98e-22

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 93.73  E-value: 1.98e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   4 YYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPEnkeeaEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLingggggshh 83
Cdd:PTZ00037   30 LYEVLNLSKDCTTSEIKKAYRKLAIKHHPDKGGD-----PEKFKEISRAYEVLSDPEKRKIYDEYGEEGL---------- 94

                          90       100
                  ....*....|....*....|...
gi 1121973574  84 dnpfEFGFTFRNPNDVFREFFGG 106
Cdd:PTZ00037   95 ----EGGEQPADASDLFDLIFGG 113
PRK14288 PRK14288
molecular chaperone DnaJ;
2-94 2.38e-22

molecular chaperone DnaJ;


Pssm-ID: 172776 [Multi-domain]  Cd Length: 369  Bit Score: 93.22  E-value: 2.38e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   2 VDYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKeEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGGS 81
Cdd:PRK14288    3 LSYYEILEVEKHSNQETIKKSYRKLALKYHPDRNAGDK-EAEEKFKLINEAYGVLSDEKKRALYDRYGKKGLNQAGASQS 81

                          90       100
                  ....*....|....*....|..
gi 1121973574  82 HHDNPFE---------FGFTFR 94
Cdd:PRK14288   82 DFSDFFEdlgsffedaFGFGAR 103
PRK14295 PRK14295
molecular chaperone DnaJ;
3-72 3.59e-22

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 92.99  E-value: 3.59e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKeEAEQQFKQVAEAYEVLSDAKKRDIYDR----FGKEG 72
Cdd:PRK14295   10 DYYKVLGVPKDATEAEIKKAYRKLAREYHPDANKGDA-KAEERFKEISEAYDVLSDEKKRKEYDEarslFGNGG 82
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
 3-106 3.88e-21

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 89.68  E-value: 3.88e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPEnkEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGkeglingggggsH 82
Cdd:PRK14287    5 DYYEVLGVDRNASVDEVKKAYRKLARKYHPDVNKA--PDAEDKFKEVKEAYDTLSDPQKKAHYDQFG------------H 70

                          90       100
                  ....*....|....*....|....*...
gi 1121973574  83 HDNPFEFGFT----FRNPNDVFREFFGG 106
Cdd:PRK14287   71 TDPNQGFGGGgagdFGGFSDIFDMFFGG 98
PRK14300 PRK14300
chaperone protein DnaJ; Provisional
 3-106 4.04e-20

chaperone protein DnaJ; Provisional


Pssm-ID: 172788 [Multi-domain]  Cd Length: 372  Bit Score: 86.99  E-value: 4.04e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNpeNKEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGGS- 81
Cdd:PRK14300    4 DYYQILGVSKTASQADLKKAYLKLAKQYHPDTT--DAKDAEKKFKEINAAYDVLKDEQKRAAYDRFGHDAFQNQQSRGGg 81

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1121973574  82 ------HHDNPFEFGftfrnpnDVFREFFGG 106
Cdd:PRK14300   82 gnhggfHPDINDIFG-------DFFSDFMGG 105
PRK10266 PRK10266
curved DNA-binding protein;
3-105 4.94e-19

curved DNA-binding protein;


Pssm-ID: 182347 [Multi-domain]  Cd Length: 306  Bit Score: 83.33  E-value: 4.94e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENkeEAEQQFKQVAEAYEVLSDAKKRDIYD---------RFGKEGL 73
Cdd:PRK10266    5 DYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEP--DAEARFKEVAEAWEVLSDEQRRAEYDqlwqhrndpQFNRQFQ 82

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1121973574  74 INGGGGGSHHDNpfefgftfrnpNDVFREFFG 105
Cdd:PRK10266   83 HGDGQSFNAEDF-----------DDIFSSIFG 103
PRK14296 PRK14296
chaperone protein DnaJ; Provisional
 3-105 1.61e-18

chaperone protein DnaJ; Provisional


Pssm-ID: 237666 [Multi-domain]  Cd Length: 372  Bit Score: 82.69  E-value: 1.61e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENkeEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGGSH 82
Cdd:PRK14296    5 DYYEVLGVSKTASEQEIRQAYRKLAKQYHPDLNKSP--DAHDKMVEINEAADVLLDKDKRKQYDQFGHAAFDGSSGFSSN 82

                          90       100
                  ....*....|....*....|....*....
gi 1121973574  83 HDNpFEFGFT------FRNPNDVFREFFG 105
Cdd:PRK14296   83 FGD-FEDLFSnmgssgFSSFTNIFSDFFG 110
DjlA COG1076
DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];
1-64 9.81e-17

DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440694 [Multi-domain]  Cd Length: 75  Bit Score: 71.75  E-value: 9.81e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1121973574   1 MVDYYEVLGVQKHASAEDIKKAYRKLALKWHPDK-----NPENKEEAEQQFKQVAEAYEVLSDAKKRDI 64
Cdd:COG1076     3 LDDAFELLGLPPDADDAELKRAYRKLQREHHPDRlaaglPEEEQRLALQKAAAINEAYETLKDPRGIDL 71
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 4-73 3.50e-12

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 64.81  E-value: 3.50e-12
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574    4 YYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENkeEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGL 73
Cdd:PTZ00341   575 FYDILGVGVNADMKEISERYFKLAENYYPPKRSGN--EGFHKFKKINEAYQILGDIDKKKMYNKFGYDGI 642
ZUO1 COG5269
Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / ...
 2-66 1.17e-07

Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227594 [Multi-domain]  Cd Length: 379  Bit Score: 51.19  E-value: 1.17e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1121973574   2 VDYYEVLGVQKH---ASAEDIKKAYRKLALKWHPDKNPENKEEAEQQ-FKQVAEAYEVLSDAKKRDIYD 66
Cdd:COG5269    43 VDLYALLGLSKYrtkAIPPQILKAHKKKVYKYHPDKTAAGGNKGCDEfFKLIQKAREVLGDRKLRLQYD 111
djlA PRK09430
co-chaperone DjlA;
3-61 1.36e-07

co-chaperone DjlA;


Pssm-ID: 236512 [Multi-domain]  Cd Length: 267  Bit Score: 50.58  E-value: 1.36e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1121973574   3 DYYEVLGVQKHASAEDIKKAYRKLALKWHPDK------NPENKEEAEQQFKQVAEAYEVLSDAKK 61
Cdd:PRK09430  201 DAYKVLGVSESDDDQEIKRAYRKLMSEHHPDKlvakglPPEMMEMAKEKAQEIQAAYELIKKQKG 265
hscB PRK01356
co-chaperone HscB; Provisional
 1-65 5.70e-06

co-chaperone HscB; Provisional


Pssm-ID: 167217 [Multi-domain]  Cd Length: 166  Bit Score: 44.87  E-value: 5.70e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   1 MVDYYEVLGVQKHASA--EDIKKAYRKLALKWHPDKnPENKEEAEQQFKQVAE---AYEVLSDAKKRDIY 65
Cdd:PRK01356    1 MQNYFQLLGLPQEYNIdlKILEKQYFAMQVKYHPDK-AKTLQEKEQNLIIASElnnAYSTLKDALKRAEY 69
PHA03102 PHA03102
Small T antigen; Reviewed
 6-37 6.36e-04

Small T antigen; Reviewed


Pssm-ID: 222986 [Multi-domain]  Cd Length: 153  Bit Score: 38.88  E-value: 6.36e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1121973574   6 EVLGVQKHA--SAEDIKKAYRKLALKWHPDK--NPE 37
Cdd:PHA03102    9 DLLGLPRSAwgNLPLMRKAYLRKCLEFHPDKggDEE 44
PHA02624 PHA02624
large T antigen; Provisional
 6-37 2.32e-03

large T antigen; Provisional


Pssm-ID: 222912 [Multi-domain]  Cd Length: 647  Bit Score: 38.43  E-value: 2.32e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1121973574   6 EVLGVQKHA--SAEDIKKAYRKLALKWHPDK--NPE 37
Cdd:PHA02624   15 DLLGLPMAAwgNLPLMRKAYLRKCKEYHPDKggDEE 50
Ubl_TECR_like cd01801
ubiquitin-like (Ubl) domain found in trans-2,3-enoyl-CoA reductase (TECR) and similar proteins; ...
 7-66 5.80e-03

ubiquitin-like (Ubl) domain found in trans-2,3-enoyl-CoA reductase (TECR) and similar proteins; This family includes TECR and many TECR-like proteins, such as TECRL. TECR, also termed very-long-chain enoyl-CoA reductase, or synaptic glycoprotein SC2, or TER, or GPSN2, is a synaptic glycoprotein that catalyzes the fourth reaction in the synthesis of very long-chain fatty acids (VLCFA) which is the reduction step of the microsomal fatty acyl-elongation process. Diseases involving perturbations to normal synthesis and degradation of VLCFA (e.g. adrenoleukodystrophy and Zellweger syndrome) have significant neurological consequences. The mammalian TECR P182L mutation causes nonsyndromic mental retardation. Deletion of the yeast TECR (TSC13) homolog is lethal. TECR contains an N-terminal ubiquitin-like (Ubl) domain with a beta-grasp Ubl fold, a common structure involved in protein-protein interactions, as well as a C-terminal catalytic domain. TECRL, also termed steroid 5-alpha-reductase 2-like 2 protein (SRD5A2L2), is associated with life-threatening inherited arrhythmias displaying features of both long QT syndrome (LQTS) and catecholaminergic polymorphic ventricular tachycardia (CPVT). Both TECR and TECRL contain an N-terminal Ubl domain with a beta-grasp Ubl fold, and a C-terminal catalytic domain.


Pssm-ID: 340499 [Multi-domain]  Cd Length: 77  Bit Score: 34.57  E-value: 5.80e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1121973574   7 VLGVQKHASAEDIKKAYRKLALKWHPDKnpenkeeaeQQFKQVAEAYEVLSDAKKRDIYD 66
Cdd:cd01801    15 TLEVSSSATVADLKKAIHKKKKKLYPER---------QRLRLEVPKGKVLKDDKTLSSYG 65
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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