NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1099280861|ref|XP_018885054|]
View 

ethylmalonyl-CoA decarboxylase isoform X2 [Gorilla gorilla gorilla]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 10787157)

enoyl-CoA hydratase/isomerase family protein similar to human ethylmalonyl-CoA decarboxylase that decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA

CATH:  3.90.226.10
Gene Ontology:  GO:0016829
PubMed:  12467702|22016388

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 49-294 6.03e-62

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


:

Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 196.54  E-value: 6.03e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  49 IDLQKEDnGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCM 128
Cdd:COG1024     1 VLVEREG-GVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFAR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 129 FMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSG 208
Cdd:COG1024    80 GLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 209 ALKLDSKNALNIGMVEEVLqSSDETksLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPA 288
Cdd:COG1024   160 GRRIDAEEALELGLVNRVV-PDDEL--LAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASED 236


                  ....*.
gi 1099280861 289 NLEAIA 294
Cdd:COG1024   237 AREGIA 242
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 49-294 6.03e-62

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 196.54  E-value: 6.03e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  49 IDLQKEDnGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCM 128
Cdd:COG1024     1 VLVEREG-GVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFAR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 129 FMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSG 208
Cdd:COG1024    80 GLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 209 ALKLDSKNALNIGMVEEVLqSSDETksLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPA 288
Cdd:COG1024   160 GRRIDAEEALELGLVNRVV-PDDEL--LAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASED 236


                  ....*.
gi 1099280861 289 NLEAIA 294
Cdd:COG1024   237 AREGIA 242
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 54-245 2.00e-53

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 172.75  E-value: 2.00e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  54 EDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMF-MQN 132
Cdd:cd06558     5 RDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALSDAGEEARAFIReLQE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 133 TLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKL 212
Cdd:cd06558    85 LLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRI 164

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1099280861 213 DSKNALNIGMVEEVLqssDETKSLEEAQEWLKQ 245
Cdd:cd06558   165 SAEEALELGLVDEVV---PDEELLAAALELARR 194
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 56-281 1.18e-29

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 112.84  E-value: 1.18e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  56 NGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFmQNTLT 135
Cdd:pfam00378   4 AGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEMYGEGPAHQALYRENV-LDLWT 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 136 RFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSK 215
Cdd:pfam00378  83 LLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQ 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1099280861 216 NALNIGMVEEVLQssdETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLG 281
Cdd:pfam00378 163 EALKWGLVDKVVP---EDQLLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFY 225
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 49-285 1.13e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 110.49  E-value: 1.13e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  49 IDLQKEDnGIGILTLNNPSKmNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCM 128
Cdd:PRK07658    4 LSVRVED-HVAVITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIHGEGRFFSAGADIKEFTSVTEAEQATELAQ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 129 FMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSG 208
Cdd:PRK07658   82 LGQVTFERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMMLT 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1099280861 209 ALKLDSKNALNIGMVEEVLqssDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWG 285
Cdd:PRK07658  162 SEPITGAEALKWGLVNGVF---PEETLLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFT 235
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 56-228 8.44e-13

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 68.71  E-value: 8.44e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  56 NGIGILTLNNP-SKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAK-NTFSSGSDLNAVKSLGTPEDGMAVCMFMQNT 133
Cdd:TIGR02441  21 GDVAVVKIDSPnSKVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKpGSFVAGADIQMIAACKTAQEVTQLSQEGQEM 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 134 LTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKE--MGIIPSWGGTTRLVEIIGSRQALKVLSGALK 211
Cdd:TIGR02441 101 FERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKTLLGLPEvmLGLLPGAGGTQRLPKLTGVPAALDMMLTGKK 180

                         170
                  ....*....|....*..
gi 1099280861 212 LDSKNALNIGMVEEVLQ 228
Cdd:TIGR02441 181 IRADRAKKMGIVDQLVD 197
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 49-294 6.03e-62

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 196.54  E-value: 6.03e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  49 IDLQKEDnGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCM 128
Cdd:COG1024     1 VLVEREG-GVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFAR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 129 FMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSG 208
Cdd:COG1024    80 GLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 209 ALKLDSKNALNIGMVEEVLqSSDETksLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPA 288
Cdd:COG1024   160 GRRIDAEEALELGLVNRVV-PDDEL--LAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASED 236


                  ....*.
gi 1099280861 289 NLEAIA 294
Cdd:COG1024   237 AREGIA 242
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 54-245 2.00e-53

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 172.75  E-value: 2.00e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  54 EDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMF-MQN 132
Cdd:cd06558     5 RDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALSDAGEEARAFIReLQE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 133 TLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKL 212
Cdd:cd06558    85 LLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRI 164

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1099280861 213 DSKNALNIGMVEEVLqssDETKSLEEAQEWLKQ 245
Cdd:cd06558   165 SAEEALELGLVDEVV---PDEELLAAALELARR 194
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 56-281 1.18e-29

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 112.84  E-value: 1.18e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  56 NGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFmQNTLT 135
Cdd:pfam00378   4 AGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEMYGEGPAHQALYRENV-LDLWT 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 136 RFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSK 215
Cdd:pfam00378  83 LLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQ 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1099280861 216 NALNIGMVEEVLQssdETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLG 281
Cdd:pfam00378 163 EALKWGLVDKVVP---EDQLLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFY 225
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 49-285 1.13e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 110.49  E-value: 1.13e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  49 IDLQKEDnGIGILTLNNPSKmNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCM 128
Cdd:PRK07658    4 LSVRVED-HVAVITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIHGEGRFFSAGADIKEFTSVTEAEQATELAQ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 129 FMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSG 208
Cdd:PRK07658   82 LGQVTFERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMMLT 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1099280861 209 ALKLDSKNALNIGMVEEVLqssDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWG 285
Cdd:PRK07658  162 SEPITGAEALKWGLVNGVF---PEETLLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFT 235
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 43-285 2.68e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 109.70  E-value: 2.68e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  43 QFPGGSIDLQKE-DNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA-KNTFSSGSDLNAVKSLGTP 120
Cdd:PRK06144    2 AMTTSTDELLLEvRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAgDKAFVAGTDIAQFRAFSTA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 121 EDGMAVCMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRF-VHKEMGIIPSWGGTTRLVEIIGS 199
Cdd:PRK06144   82 EDAVAYERRIDRVLGALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFpIARTLGNCLSMSNLARLVALLGA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 200 RQALKVLSGALKLDSKNALNIGMVEEVLQssDETKSlEEAQEWLKQFIQGPPEVIRALKKSVcsgRELyLEEALQNERDL 279
Cdd:PRK06144  162 ARVKDMLFTARLLEAEEALAAGLVNEVVE--DAALD-ARADALAELLAAHAPLTLRATKEAL---RRL-RREGLPDGDDL 234


                  ....*.
gi 1099280861 280 LGTVWG 285
Cdd:PRK06144  235 IRMCYM 240
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
44-260 2.48e-27

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 111.49  E-value: 2.48e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  44 FPGGSIDLQKEDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSL-GTPED 122
Cdd:PRK11730    3 YQGKTLQVDWLEDGIAELVFDAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLTSAKDAFIVGADITEFLSLfAAPEE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 123 G-MAVCMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQ 201
Cdd:PRK11730   83 ElSQWLHFANSIFNRLEDLPVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGADN 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1099280861 202 ALKVLSGALKLDSKNALNIGMVEEVLqSSDetKSLEEAQEWLKQFIQGPPE--VIRALKKS 260
Cdd:PRK11730  163 ALEWIAAGKDVRAEDALKVGAVDAVV-APE--KLQEAALALLKQAIAGKLDwkARRQPKLE 220
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 51-294 1.87e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 104.56  E-value: 1.87e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  51 LQKEDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAV-KSLGTPEDGMAvcmf 129
Cdd:PRK06688    8 LVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGRAFSAGGDIKDFpKAPPKPPDELA---- 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 130 mqnTLTRFMR----LPLISVALVQGWALGGGAEFTTACDFR-------LMTPESKIrfvhkemGIIPSWGGTTRLVEIIG 198
Cdd:PRK06688   84 ---PVNRFLRaiaaLPKPVVAAVNGPAVGVGVSLALACDLVyasesakFSLPFAKL-------GLCPDAGGSALLPRLIG 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 199 S-RQALKVLSGAlKLDSKNALNIGMVEEVLQSSDetkSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNER 277
Cdd:PRK06688  154 RaRAAEMLLLGE-PLSAEEALRIGLVNRVVPAAE---LDAEADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREA 229

                         250
                  ....*....|....*..
gi 1099280861 278 DLLGTVWGGPANLEAIA 294
Cdd:PRK06688  230 AGFGRLLRTPDFREGAT 246
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 55-277 1.64e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 102.12  E-value: 1.64e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  55 DNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKN-TFSSGSDLNAVKSLGTPEDGMAVCMfMQNT 133
Cdd:PRK07657   11 TPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEkAFCAGADLKERAGMNEEQVRHAVSL-IRTT 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 134 LTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLD 213
Cdd:PRK07657   90 MEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRIS 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1099280861 214 SKNALNIGMVEEVLQSSdetKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNER 277
Cdd:PRK07657  170 AQEAKEIGLVEFVVPAH---LLEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEK 230
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
49-281 2.58e-24

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 99.05  E-value: 2.58e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  49 IDLQKEDNgIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA-KNTFSSGSDLNAVKSLgTPEDGMAVC 127
Cdd:PRK05809    6 VILEKEGH-IAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAgEKAFVAGADISEMKDL-NEEEGRKFG 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 128 MFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTpeSKIRFVHKE--MGIIPSWGGTTRLVEIIGSRQALKV 205
Cdd:PRK05809   84 LLGNKVFRKLENLDKPVIAAINGFALGGGCELSMACDIRIAS--EKAKFGQPEvgLGITPGFGGTQRLARIVGPGKAKEL 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1099280861 206 LSGALKLDSKNALNIGMVEEVLQSSdetKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLG 281
Cdd:PRK05809  162 IYTGDMINAEEALRIGLVNKVVEPE---KLMEEAKALANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAEDFG 234
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 51-277 8.09e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 97.43  E-value: 8.09e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  51 LQKEDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEdgmavcMFM 130
Cdd:PRK08138   11 LERPADGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTGGEKVFAAGADIKEFATAGAIE------MYL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 131 QNT------LTRfMRLPLIsvALVQGWALGGGAEFTTACDF-------RLMTPESKIrfvhkemGIIPSWGGTTRLVEII 197
Cdd:PRK08138   85 RHTeryweaIAQ-CPKPVI--AAVNGYALGGGCELAMHADIivagesaSFGQPEIKV-------GLMPGAGGTQRLVRAV 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 198 GSRQALK-VLSGALkLDSKNALNIGMVEEVlqsSDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNE 276
Cdd:PRK08138  155 GKFKAMRmALTGCM-VPAPEALAIGLVSEV---VEDEQTLPRALELAREIARMPPLALAQIKEVVLAGADAPLDAALALE 230


                  .
gi 1099280861 277 R 277
Cdd:PRK08138  231 R 231
PLN02888 PLN02888
enoyl-CoA hydratase
 49-279 8.83e-24

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 97.52  E-value: 8.83e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  49 IDLQKEDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSL--GTPEDGMAv 126
Cdd:PLN02888   11 ILVPKSRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGRAFCSGVDLTAAEEVfkGDVKDVET- 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 127 cmfmqNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVL 206
Cdd:PLN02888   90 -----DPVAQMERCRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVS 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1099280861 207 SGALKLDSKNALNIGMVEEVLqssDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDL 279
Cdd:PLN02888  165 LTAMPLTAETAERWGLVNHVV---EESELLKKAREVAEAIIKNNQGMVLRYKSVINDGLKLDLGHALQLEKER 234
PLN02600 PLN02600
enoyl-CoA hydratase
 55-294 8.84e-24

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 97.18  E-value: 8.84e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  55 DNGIGILTLNNPSKMNAFsGVMMLQLLEKVIE-LENWTEGKGLIVRGA-KNTFSSGSDLNAVKSLGTPEDGMAVCMfMQN 132
Cdd:PLN02600    2 DSGIVELRLDRPEAKNAI-GKEMLRGLRSAFEkIQADASARVVMLRSSvPGVFCAGADLKERRKMSPSEVQKFVNS-LRS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 133 TLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKL 212
Cdd:PLN02600   80 TFSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRI 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 213 DSKNALNIGMVEEVLQSSDE-TKSLEEAQEwlkqFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPANLE 291
Cdd:PLN02600  160 GAREAASMGLVNYCVPAGEAyEKALELAQE----INQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLE 235


                  ...
gi 1099280861 292 AIA 294
Cdd:PLN02600  236 GLA 238
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 55-261 3.37e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 95.56  E-value: 3.37e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  55 DNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAV--KSLGTPEDGMAVcmfMQN 132
Cdd:PRK05870   10 DDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAGKAFCAGADLTALgaAPGRPAEDGLRR---IYD 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 133 TLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESK--IRFVhkEMGIIPSWGGTTRLVEIIGSRQALKVLSGAL 210
Cdd:PRK05870   87 GFLAVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALfdARFQ--KLGLHPGGGATWMLQRAVGPQVARAALLFGM 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1099280861 211 KLDSKNALNIGMVEEVlqsSDETksLEEAQEWLKQFIQGPPEVIRALKKSV 261
Cdd:PRK05870  165 RFDAEAAVRHGLALMV---ADDP--VAAALELAAGPAAAPRELVLATKASM 210
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 55-278 1.83e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 93.95  E-value: 1.83e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  55 DNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA-KNTFSSGSDLN---AVKSLGTPEDGMAvcmfm 130
Cdd:PRK06494   11 KGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAgDKAFSAGNDLKeqaAGGKRGWPESGFG----- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 131 qnTLT-RF-MRLPLIsvALVQGWALGGGAEFTTACD---------FRLmtPESKIrfvhkemGIIPSWGGTTRLVEIIGS 199
Cdd:PRK06494   86 --GLTsRFdLDKPII--AAVNGVAMGGGFELALACDlivaaenatFAL--PEPRV-------GLAALAGGLHRLPRQIGL 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1099280861 200 RQALKVLSGALKLDSKNALNIGMVEEVLQSSDetkSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERD 278
Cdd:PRK06494  153 KRAMGMILTGRRVTAREGLELGFVNEVVPAGE---LLAAAERWADDILACSPLSIRASKQAVYRGLEVSLEEAITAQRD 228
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 45-294 2.01e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 93.50  E-value: 2.01e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  45 PGGSIDLQKEDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLnavKSLGTPEDGM 124
Cdd:PRK06190    1 MTEPILLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGADPAFCAGLDL---KELGGDGSAY 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 125 AVCMFMQNTLTRF--MRLPLISValVQGWALGGGAEFTTACDFrLMTPEsKIRF--VHKEMGIIPSWGGTTRLVEIIGSR 200
Cdd:PRK06190   78 GAQDALPNPSPAWpaMRKPVIGA--INGAAVTGGLELALACDI-LIASE-RARFadTHARVGILPGWGLSVRLPQKVGIG 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 201 QALKV-LSGALkLDSKNALNIGMVEEVLQSSDetkSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDL 279
Cdd:PRK06190  154 RARRMsLTGDF-LDAADALRAGLVTEVVPHDE---LLPRARRLAASIAGNNPAAVRALKASYDDGAAAQTGDALALEAEA 229

                         250
                  ....*....|....*
gi 1099280861 280 LGTvWGGPANLEAIA 294
Cdd:PRK06190  230 ARA-HNRSVSPDGIA 243
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
49-298 1.50e-21

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 91.48  E-value: 1.50e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  49 IDLQKEDnGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDL--------NAVKSLGTP 120
Cdd:PRK07509    5 VSVTIED-GIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEGGAFCAGLDVksvasspgNAVKLLFKR 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 121 EDGMA-----VCMFMQntltrfmRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVE 195
Cdd:PRK07509   84 LPGNAnlaqrVSLGWR-------RLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 196 IIGSRQALKVLSGALKLDSKNALNIGMVEEVlqsSDETksLEEAQEWLKQFIQGPPEVIRALKKS-----VCSGRELYLE 270
Cdd:PRK07509  157 LVRKDVARELTYTARVFSAEEALELGLVTHV---SDDP--LAAALALAREIAQRSPDAIAAAKRLinrswTASVRALLAR 231

                         250       260
                  ....*....|....*....|....*...
gi 1099280861 271 EALQNERdLLgtvwGGPANLEAIAKKGK 298
Cdd:PRK07509  232 ESVEQIR-LL----LGKNQKIAVKAQMK 254
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 48-294 4.89e-21

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 89.83  E-value: 4.89e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  48 SIDLQKEDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLN--AVKSLGTPEDGMA 125
Cdd:PRK09674    2 SELLVSRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGNARFFAAGADLNemAEKDLAATLNDPR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 126 VCMFMQntLTRFMRlPLIsvALVQGWALGGGAEFTTACDfrLMTPESKIRFVHKE--MGIIPSWGGTTRLVEIIGSRQAL 203
Cdd:PRK09674   82 PQLWQR--LQAFNK-PLI--AAVNGYALGAGCELALLCD--IVIAGENARFGLPEitLGIMPGAGGTQRLIRSVGKSLAS 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 204 K-VLSGAlKLDSKNALNIGMVEEVLQSSdetKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGT 282
Cdd:PRK09674  155 QmVLTGE-SITAQQAQQAGLVSEVFPPE---LTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTL 230

                         250
                  ....*....|..
gi 1099280861 283 VWGGPANLEAIA 294
Cdd:PRK09674  231 LAATEDRHEGIS 242
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 48-294 1.55e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 88.44  E-value: 1.55e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  48 SIDLQKEDNG-IGILTLNNPSKmNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTF-SSGSDLNavkslgTPEDG-- 123
Cdd:PRK09076    2 MIELDLEIDGhVAILTLNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGEKFfSAGADLN------LFADGdk 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 124 -----MAVCM---FmqNTLTRFMRlplISVALVQGWALGGGAEFTTACDFR-------LMTPESKIrfvhkemGIIPSWG 188
Cdd:PRK09076   75 avareMARRFgeaF--EALSAFRG---VSIAAINGYAMGGGLECALACDIRiaeeqaqMALPEASV-------GLLPCAG 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 189 GTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLqssDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELY 268
Cdd:PRK09076  143 GTQNLPWLVGEGWAKRMILCGERVDAATALRIGLVEEVV---EKGEAREAALALAQKVANQSPSAVAACKTLIQAARNGP 219

                         250       260
                  ....*....|....*....|....*.
gi 1099280861 269 LEEALQNERDLLGTVWGGPANLEAIA 294
Cdd:PRK09076  220 RAAALALERELFVDLFDTEDQREGVN 245
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
 48-278 2.06e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 88.17  E-value: 2.06e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  48 SIDLQKEDNgIGILTLNNPSKMNAFSGVMMLQLLEKVIELENwTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVC 127
Cdd:PRK07659    7 SVVVKYEGR-VATIMLNRPEALNALDEPMLKELLQALKEVAE-SSAHIVVLRGNGRGFSAGGDIKMMLSSNDESKFDGVM 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 128 MFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLS 207
Cdd:PRK07659   85 NTISEIVVTLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGENKAKQIIW 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1099280861 208 GALKLDSKNALNIGMVEEVLQSSdetkSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERD 278
Cdd:PRK07659  165 EGKKLSATEALDLGLIDEVIGGD----FQTAAKQKISEWLQKPLKAMIETKQIYCELNRSQLEQVLQLEKR 231
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
 41-261 3.23e-20

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 86.82  E-value: 3.23e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  41 LQQFPGGSIDLQKEDNGIGILTLNNPSKmNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTP 120
Cdd:PRK05869    1 MNEFVNVVVSDGSQDAGLATLLLSRPPT-NALTRQVYREIVAAANELGRRDDVAAVILYGGHEIFSAGDDMPELRTLSAQ 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 121 EDGMA--VCmfmQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIG 198
Cdd:PRK05869   80 EADTAarVR---QQAVDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAG 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1099280861 199 SRQALK-VLSGALkLDSKNALNIGMVEEVLQSSDetkSLEEAQEWLKQFIQGPPEVIRALKKSV 261
Cdd:PRK05869  157 PSRAKElVFSGRF-FDAEEALALGLIDEMVAPDD---VYDAAAAWARRFLDGPPHALAAAKAGI 216
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
51-230 3.45e-20

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 90.73  E-value: 3.45e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  51 LQKEDNGIGILTLNNP-SKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAK-NTFSSGSDLNAVKSLGTPEDGMAVCM 128
Cdd:PRK11154    9 LNVREDNIAVITIDVPgEKMNTLKAEFAEQVRAILKQLREDKELKGVVFISGKpDNFIAGADINMLAACKTAQEAEALAR 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 129 FMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKE--MGIIPSWGGTTRLVEIIGSRQALK-V 205
Cdd:PRK11154   89 QGQQLFAEIEALPIPVVAAIHGACLGGGLELALACHYRVCTDDPKTVLGLPEvqLGLLPGSGGTQRLPRLIGVSTALDmI 168

                         170       180
                  ....*....|....*....|....*
gi 1099280861 206 LSGAlKLDSKNALNIGMVEEVLQSS 230
Cdd:PRK11154  169 LTGK-QLRAKQALKLGLVDDVVPHS 192
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 41-279 7.67e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 83.99  E-value: 7.67e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  41 LQQFPGGSIDLQKEDnGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA-KNTFSSGSDLNAV-KSLG 118
Cdd:PRK06127    5 SISSPTGKLLAEKTG-GLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAgEKAFVSGADISQFeESRS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 119 TPEdgmAVCMFMQNTLTRFMRL---PLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVE 195
Cdd:PRK06127   84 DAE---AVAAYEQAVEAAQAALadyAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVD 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 196 IIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSDetksLE-EAQEWLKQFIQGPPEVIRALKKSVcsgRELYLEEAlq 274
Cdd:PRK06127  161 LVGPSAAKDLFYTARRFDAAEALRIGLVHRVTAADD----LEtALADYAATIAGNAPLTLRAAKRAI---AELLKDEP-- 231


                  ....*
gi 1099280861 275 nERDL 279
Cdd:PRK06127  232 -ERDM 235
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 49-226 1.72e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 83.52  E-value: 1.72e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  49 IDLQKEDnGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNA-VKSLGTPEDGMAVC 127
Cdd:PRK08260    6 IRYDVAD-GIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAGRAFCAGADLSAgGNTFDLDAPRTPVE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 128 MFM----------------QNTLTRF-MRLPLIsvALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGT 190
Cdd:PRK08260   85 ADEedradpsddgvrdgggRVTLRIFdSLKPVI--AAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASS 162

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1099280861 191 TRLVEIIGSRQALK-VLSGALkLDSKNALNIGMVEEV 226
Cdd:PRK08260  163 WFLPRLVGLQTALEwVYSGRV-FDAQEALDGGLVRSV 198
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
 55-279 2.22e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 82.65  E-value: 2.22e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  55 DNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENwTEGKGLIVRGAKNTFSSGSDLN--AVKSLGTPED-GMAVCMFMQ 131
Cdd:PRK08140   11 EAGVATLTLNRPDKLNSFTREMHRELREALDQVED-DGARALLLTGAGRGFCAGQDLAdrDVTPGGAMPDlGESIETFYN 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 132 NTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKirFVHK--EMGIIPSWGGTTRLVEIIGSRQALKVLSGA 209
Cdd:PRK08140   90 PLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSAS--FIQAfvKIGLVPDSGGTWFLPRLVGMARALGLALLG 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 210 LKLDSKNALNIGMVEEVLqssDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDL 279
Cdd:PRK08140  168 EKLSAEQAEQWGLIWRVV---DDAALADEAQQLAAHLATQPTRGLALIKQAMNASATNTLDAQLDLERDL 234
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 58-279 1.69e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 80.09  E-value: 1.69e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  58 IGILTLNNPSKMNAFSGVMMLQLLEKVIELENwTEGKGLIV-RGAKNTFSSGSDLNAVKSLgtpeDGMAVcmFMQNTLT- 135
Cdd:PRK05862   14 VGLITLNRPKALNALNDALMDELGAALAAFDA-DEGIGAIViTGSEKAFAAGADIKEMADL----SFMDV--YKGDYITn 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 136 ----RFMRLPLIsvALVQGWALGGGAEFTTACDF-------RLMTPESKirfvhkeMGIIPSWGGTTRLVEIIGSRQALK 204
Cdd:PRK05862   87 wekvARIRKPVI--AAVAGYALGGGCELAMMCDIiiaadtaKFGQPEIK-------LGVLPGMGGSQRLTRAVGKAKAMD 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1099280861 205 VLSGALKLDSKNALNIGMVEEVLQSSdetKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDL 279
Cdd:PRK05862  158 LCLTGRMMDAAEAERAGLVSRVVPAD---KLLDEALAAATTIASFSLPAVMMAKEAVNRAYETTLAEGLLFERRL 229
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
55-277 1.56e-16

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 77.47  E-value: 1.56e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  55 DNGIGILTLNNPSKMNAFSGVMMLQLLE--KVIElENWTEGKGLIVRGAKNTFSSGSDL----NAVKSLGTPED-GMAVC 127
Cdd:PRK05981   11 DGGVAILTLDHPEVMNAVSIDMLGGLAEalDAIE-DGKAEVRCLVLTGAGRGFCTGANLqgrgSGGRESDSGGDaGAALE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 128 MFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLS 207
Cdd:PRK05981   90 TAYHPFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGKARAMELSL 169

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 208 GALKLDSKNALNIGMVEEVLqssDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNER 277
Cdd:PRK05981  170 LGEKLPAETALQWGLVNRVV---DDAELMAEAMKLAHELANGPTVALGLIRKLYWDSPENDFEEQLNLER 236
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
55-258 1.25e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 75.01  E-value: 1.25e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  55 DNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTP----------EDGM 124
Cdd:PRK06142   13 ADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKHFSYGIDLPAMAGVFGQlgkdglarprTDLR 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 125 AVCMFMQNTLTRF--MRLPLIsvALVQGWALGGGAEFTTACDFRLMTPESKirFVHKE--MGIIPSWGGTTRLVEIIGSR 200
Cdd:PRK06142   93 REILRLQAAINAVadCRKPVI--AAVQGWCIGGGVDLISACDMRYASADAK--FSVREvdLGMVADVGSLQRLPRIIGDG 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1099280861 201 QALKVLSGALKLDSKNALNIGMVEEVLqsSDETKSLEEAQEWLKQFIQGPPEVIRALK 258
Cdd:PRK06142  169 HLRELALTGRDIDAAEAEKIGLVNRVY--DDADALLAAAHATAREIAAKSPLAVRGTK 224
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
57-283 1.70e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 74.64  E-value: 1.70e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  57 GIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAV---KSLGTPEDGMAvcmfmqnT 133
Cdd:PRK08252   12 RVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAGGTFCAGMDLKAFargERPSIPGRGFG-------G 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 134 LT-RFMRLPLIsvALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALK-VLSGALk 211
Cdd:PRK08252   85 LTeRPPRKPLI--AAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMElALTGDM- 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1099280861 212 LDSKNALNIGMVEEVlqsSDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTV 283
Cdd:PRK08252  162 LTAERAHELGLVNRL---TEPGQALDAALELAERIAANGPLAVAASKRIVVESGDWSEDEMFARQRELIAPV 230
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
60-297 2.97e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 73.98  E-value: 2.97e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  60 ILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGtPEDGMAVCMFMQNTLT---- 135
Cdd:PRK07799   17 IVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGGAFCAGMDLKAATKKP-PGDSFKDGSYDPSRIDallk 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 136 -RFMRLPLIsvALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDS 214
Cdd:PRK07799   96 gRRLTKPLI--AAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDLLLTGRHITA 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 215 KNALNIGMVEEVLqssDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLlgtvwGGPANLEAIA 294
Cdd:PRK07799  174 AEAKEIGLIGHVV---PDGQALDKALELAELINANGPLAVQAILRTIRETEGMHENEAFKIDTKI-----GIPVFLSEDA 245


                  ...
gi 1099280861 295 KKG 297
Cdd:PRK07799  246 KEG 248
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
55-273 4.39e-15

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 73.58  E-value: 4.39e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  55 DNGIGILTLNNPsKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA-KNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNT 133
Cdd:PRK03580   10 NGSILEITLDRP-KANAIDAKTSFAMGEVFLNFRDDPELRVAIITGAgEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLT 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 134 LTRFMRLPLIsvALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLD 213
Cdd:PRK03580   89 EIFDLDKPVI--AAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMVMTGRRMD 166

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 214 SKNALNIGMVEEVLQSsdeTKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEAL 273
Cdd:PRK03580  167 AEEALRWGIVNRVVPQ---AELMDRARELAQQLVNSAPLAIAALKEIYRETSEMPVEEAY 223
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 55-272 5.49e-15

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 73.50  E-value: 5.49e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  55 DNGIGILTLNNPSKMNAFSGVM---MLQLLEkviELENWTEGKGLIVRGAKNTFSSGSDLNAV--KSLGTPEdgMAVCMF 129
Cdd:PRK09120   15 EDGIAWVTLNRPEKRNAMSPTLnreMIDVLD---ALEFDDDAGVLVLTGAGDAWSAGMDLKEYfrETDAQPE--ILQERI 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 130 MQNTLTRFMRL---PLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQAL-KV 205
Cdd:PRK09120   90 RREAYGWWRRLrwyQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTVGHRDALyYI 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1099280861 206 LSGALkLDSKNALNIGMVEEVLQSSD-ETKSLEEAQEWLKQfiqgPPEVIRALKKSVCSGRELYLEEA 272
Cdd:PRK09120  170 MTGET-FTGRKAAEMGLVNESVPLAQlRARTRELAAKLLEK----NPVVLRAAKDGFKRVRELTWDQA 232
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
55-260 1.12e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 72.30  E-value: 1.12e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  55 DNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAV------KSLGTPEDGMAVCM 128
Cdd:PRK06563    6 RGHVLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGEHFTAGLDLADVapklaaGGFPFPEGGIDPWG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 129 FMQNTLTRfmrlPLISValVQGWALGGGAEFTTACDFRLMTpeSKIRFVHKEM--GIIPSWGGTTRLVEIIGSRQALKVL 206
Cdd:PRK06563   86 TVGRRLSK----PLVVA--VQGYCLTLGIELMLAADIVVAA--DNTRFAQLEVqrGILPFGGATLRFPQAAGWGNAMRYL 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1099280861 207 SGALKLDSKNALNIGMVEEVLQSSDE-TKSLEEAQEWLKQfiqgPPEVIRALKKS 260
Cdd:PRK06563  158 LTGDEFDAQEALRLGLVQEVVPPGEQlERAIELAERIARA----APLGVQATLAS 208
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
 48-258 1.18e-14

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 72.15  E-value: 1.18e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  48 SIDLQKEDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSL------GTPE 121
Cdd:PRK05674    6 TIELIRDPRGFATLWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRGRHFSAGADLAWMQQSadldynTNLD 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 122 DGMAVCMFMQNtltrFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTrLVEIIGSRQ 201
Cdd:PRK05674   86 DARELAELMYN----LYRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISPF-VVKAIGERA 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1099280861 202 ALKVLSGALKLDSKNALNIGMVEEVLQSSDetksLE-EAQEWLKQFIQGPPEVIRALK 258
Cdd:PRK05674  161 ARRYALTAERFDGRRARELGLLAESYPAAE----LEaQVEAWIANLLLNSPQALRASK 214
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
 54-292 3.21e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 70.82  E-value: 3.21e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  54 EDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENwTEGKGLIVRGAKNTFSSGSDLNAVkslGTPEDGMAVCMFMQNT 133
Cdd:PRK07854    6 RDGQVLTIELQRPERRNALNAELCEELREAVRKAVD-ESARAIVLTGQGTVFCAGADLSGD---VYADDFPDALIEMLHA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 134 LTRfmrLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGI-IPSWgGTTRLVEIIGSRQALKVLSGALKL 212
Cdd:PRK07854   82 IDA---APVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIaLDNW-TIRRLSSLVGGGRARAMLLGAEKL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 213 DSKNALNIGMVEEVlqssdetKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRElyLEEALQNERDLLGTVWGGPANLEA 292
Cdd:PRK07854  158 TAEQALATGMANRI-------GTLADAQAWAAEIAGLAPLALQHAKRVLNDDGA--IEEAWPAHKELFDKAWASQDAIEA 228
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
55-274 1.30e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 69.23  E-value: 1.30e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  55 DNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEG-KGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVcMFMQNT 133
Cdd:PRK09245   10 DGHIVTLTMNRPETRNALSDNDAVDALVAACAAINADRSvRAVILTGAGTAFSSGGNVKDMRARVGAFGGSPA-DIRQGY 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 134 LTRFMRLPLI-------SVALVQGWALGGGAEFTTACDFRLMTPESKI--RFVhkEMGIIPSWGGTTRLVEIIG-SRQAL 203
Cdd:PRK09245   89 RHGIQRIPLAlynlevpVIAAVNGPAIGAGCDLACMCDIRIASETARFaeSFV--KLGLIPGDGGAWLLPRIIGmARAAE 166

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1099280861 204 KVLSGAlKLDSKNALNIGMVEEVLQSSDetkSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQ 274
Cdd:PRK09245  167 MAFTGD-AIDAATALEWGLVSRVVPADQ---LLPAARALAERIAANPPHALRLTKRLLREGQHASLDTLLE 233
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
 55-273 2.42e-13

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 68.78  E-value: 2.42e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  55 DNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSL----GTPEDGMAV---- 126
Cdd:PLN02664   15 NSSVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAGDHFCSGIDLKTLNSIseqsSSGDRGRSGerlr 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 127 --CMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALK 204
Cdd:PLN02664   95 rkIKFLQDAITAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGNAME 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 205 VLSGALKLDSKNALNIGMVEEVLQSSDEtksLEEAQEWLKQFIQG-PPEVIRALKKSVCSGRELYLEEAL 273
Cdd:PLN02664  175 LALTGRRFSGSEAKELGLVSRVFGSKED---LDEGVRLIAEGIAAkSPLAVTGTKAVLLRSRELSVEQGL 241
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
 45-271 6.69e-13

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 67.60  E-value: 6.69e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  45 PGGSIDLQKEDNGIGILTLNNpSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA--KNTFSSGSDLNAVKSLGTPED 122
Cdd:PLN03214    9 ATPGVRVDRRPGGIAVVWLAK-EPVNSMTLAMWRSLDDALTALENDPTVRGVVFASGlrRDVFTAGNDIAELYAPKTSAA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 123 GMAVCMFMQNT-LTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGI-IPSWGGTTRLVEIIGSR 200
Cdd:PLN03214   88 RYAEFWLTQTTfLVRLLRSRLATVCAIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIpVPKFWARLFMGRVIDRK 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1099280861 201 QA-LKVLSGALkLDSKNALNIGMVEEVLQSSdetKSLEEAQEWLKQFIQGPPEVIRALKKSV----CSGRELYLEE 271
Cdd:PLN03214  168 VAeSLLLRGRL-VRPAEAKQLGLIDEVVPAA---ALMEAAASAMERALKLPSAARAATKALLreefSAAWEAYYEE 239
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 56-228 8.44e-13

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 68.71  E-value: 8.44e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  56 NGIGILTLNNP-SKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAK-NTFSSGSDLNAVKSLGTPEDGMAVCMFMQNT 133
Cdd:TIGR02441  21 GDVAVVKIDSPnSKVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKpGSFVAGADIQMIAACKTAQEVTQLSQEGQEM 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 134 LTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKE--MGIIPSWGGTTRLVEIIGSRQALKVLSGALK 211
Cdd:TIGR02441 101 FERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKTLLGLPEvmLGLLPGAGGTQRLPKLTGVPAALDMMLTGKK 180

                         170
                  ....*....|....*..
gi 1099280861 212 LDSKNALNIGMVEEVLQ 228
Cdd:TIGR02441 181 IRADRAKKMGIVDQLVD 197
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
54-241 2.79e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 65.43  E-value: 2.79e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  54 EDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENwtEGKGLIVRGAKNTFSSGSDLNAVKSLgTPEDGMAVCMFMQNT 133
Cdd:PRK08150    8 LDGGVATIGLNRPAKRNALNDGLIAALRAAFARLPE--GVRAVVLHGEGDHFCAGLDLSELRER-DAGEGMHHSRRWHRV 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 134 LTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIG-SRQALKVLSGALkL 212
Cdd:PRK08150   85 FDKIQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGvARMTDMMLTGRV-Y 163

                         170       180
                  ....*....|....*....|....*....
gi 1099280861 213 DSKNALNIGMVEEVLQSSdetKSLEEAQE 241
Cdd:PRK08150  164 DAQEGERLGLAQYLVPAG---EALDKAME 189
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
55-250 3.23e-12

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 65.37  E-value: 3.23e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  55 DNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLN----AVKSLGTPEdgmaVCMF- 129
Cdd:PRK08258   24 DDGVATITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGGNFCSGGDVHeiigPLTKMDMPE----LLAFt 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 130 -MQNTLTRFMR-LPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPS-WGGTTRLVEIIGSRQALKVL 206
Cdd:PRK08258  100 rMTGDLVKAMRaCPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVGLAGAdMGACALLPRIIGQGRASELL 179

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1099280861 207 SGALKLDSKNALNIGMVEEVLQSSDetkSLEEAQEWLKQFIQGP 250
Cdd:PRK08258  180 YTGRSMSAEEGERWGFFNRLVEPEE---LLAEAQALARRLAAGP 220
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
 49-260 7.32e-12

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 64.10  E-value: 7.32e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  49 IDLQKEDNGIGILTLNNPSKMNAFSGVMMLQLLeKVIELENWTEGKGLIV---RGAKnTFSSGSDlNAVKSLGTPEDGMA 125
Cdd:TIGR01929   4 IRYEKSTDGIAKITINRPQVRNAFRPLTVKEII-QALDDAREDPDIGVVIltgAGDK-AFCSGGD-QKVRGDYGYIDDSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 126 VCMFMQNTLTRFMR-LPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALK 204
Cdd:TIGR01929  81 VHRLNVLDVQRQIRtCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMARIVGQKKARE 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1099280861 205 VLSGALKLDSKNALNIGMVEEVLQSSDetksLE-EAQEWLKQFIQGPPEVIRALKKS 260
Cdd:TIGR01929 161 IWFLCRQYDAKQALDMGLVNTVVPLAD----LEkETVRWCREILQKSPMAIRMLKAA 213
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 61-261 7.53e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 64.18  E-value: 7.53e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  61 LTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLG--TPEDGMAVCMFMQNTLTRFM 138
Cdd:PRK05995   17 VTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKAFCAGADLNWMKKMAgySDDENRADARRLADMLRAIY 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 139 RLPLISVALVQGWALGGGAEFTTACDF-------RLMTPESKIrfvhkemGIIPSwggtT---RLVEIIGSRQALKVLSG 208
Cdd:PRK05995   97 RCPKPVIARVHGDAYAGGMGLVAACDIavaadhaVFCLSEVRL-------GLIPA----TispYVIRAMGERAARRYFLT 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1099280861 209 ALKLDSKNALNIGMVEEVLqSSDEtksLEEAQEWL-KQFIQGPPEVIRALKKSV 261
Cdd:PRK05995  166 AERFDAAEALRLGLVHEVV-PAEA---LDAKVDELlAALVANSPQAVRAGKRLV 215
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
 55-231 1.41e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 63.57  E-value: 1.41e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  55 DNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGtPEDGMA---VCMFMQ 131
Cdd:PRK06210   13 DSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRGFCAGADMGELQTID-PSDGRRdtdVRPFVG 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 132 N----TLTRF-----MRLPLIsvALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQA 202
Cdd:PRK06210   92 NrrpdYQTRYhfltaLRKPVI--AAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRLVGHANA 169

                         170       180
                  ....*....|....*....|....*....
gi 1099280861 203 LKVLSGALKLDSKNALNIGMVEEVLQSSD 231
Cdd:PRK06210  170 LDLLLSARTFYAEEALRLGLVNRVVPPDE 198
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
 57-223 2.60e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 62.93  E-value: 2.60e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  57 GIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNA------VKSLGTPEDGMAVCMFM 130
Cdd:PRK05864   19 EIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRGFSSGADHKSagvvphVEGLTRPTYALRSMELL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 131 QNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLV-EIIGSRQALKVLSGA 209
Cdd:PRK05864   99 DDVILALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTASELGLSYLLpRAIGSSRAFEIMLTG 178

                         170
                  ....*....|....
gi 1099280861 210 LKLDSKNALNIGMV 223
Cdd:PRK05864  179 RDVDAEEAERIGLV 192
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
45-276 4.14e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 61.84  E-value: 4.14e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  45 PGGSIDLQKeDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVkslGTPE--- 121
Cdd:PRK08259    1 MSMSVRVER-NGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGGTFCAGADLKAV---GTGRgnr 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 122 -----DG-MAVcmfmqntlTRfMRL--PLIsvALVQGWALGGGAEFTTACDFRLMTPESKI-----RFvhkemGIIPSWG 188
Cdd:PRK08259   77 lhpsgDGpMGP--------SR-MRLskPVI--AAVSGYAVAGGLELALWCDLRVAEEDAVFgvfcrRW-----GVPLIDG 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 189 GTTRLVEIIGSRQALK-VLSGAlKLDSKNALNIGMVEEVLQSSDetkSLEEAQEWLKQFIQGPPEVIRALKKSVCSGREL 267
Cdd:PRK08259  141 GTVRLPRLIGHSRAMDlILTGR-PVDADEALAIGLANRVVPKGQ---ARAAAEELAAELAAFPQTCLRADRLSALEQWGL 216


                  ....*....
gi 1099280861 268 YLEEALQNE 276
Cdd:PRK08259  217 PEEAALANE 225
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
 55-230 5.55e-11

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 61.58  E-value: 5.55e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  55 DNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENwTEGKGLIVRGAKNT--FSSGSDLNAVKSLGtpEDGMAVCMFMQN 132
Cdd:PRK11423   11 INKIATITFNNPAKRNALSKVLIDDLMQALSDLNR-PEIRVVILRAPSGSkvWSAGHDIHELPSGG--RDPLSYDDPLRQ 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 133 TLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKL 212
Cdd:PRK11423   88 ILRMIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSGILNFTNDAGFHIVKEMFFTASPI 167

                         170
                  ....*....|....*...
gi 1099280861 213 DSKNALNIGMVEEVLQSS 230
Cdd:PRK11423  168 TAQRALAVGILNHVVEVE 185
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 53-275 3.54e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 59.28  E-value: 3.54e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  53 KEDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA-KNTFSSGSDLNAVKSLgTPEDGMAVcmfmq 131
Cdd:PRK06143   12 RDDRGVATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAgEKAFIGGADIKEMATL-DQASAEAF----- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 132 ntLTRFMRL-------PLISVALVQGWALGGGAEFTTACDFRLMT-------PESKIrfvhkemGiIPSWGGTTRLVEII 197
Cdd:PRK06143   86 --ISRLRDLcdavrhfPVPVIARIPGWCLGGGLELAAACDLRIAAhdaqfgmPEVRV-------G-IPSVIHAALLPRLI 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1099280861 198 G-SRQALKVLSGALkLDSKNALNIGMVEEVLQSSDETKSLEEAQEWLKQFiqgPPEVIRALKKSVCSGRELYLEEALQN 275
Cdd:PRK06143  156 GwARTRWLLLTGET-IDAAQALAWGLVDRVVPLAELDAAVERLAASLAGC---GPQALRQQKRLLREWEDMPLDVAIDD 230
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
48-294 2.79e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 56.61  E-value: 2.79e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  48 SIDLQKEDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSL--GTPED--- 122
Cdd:PRK07468    5 TIRIAVDARGVATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAGKSFCAGGDLGWMRAQmtADRATrie 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 123 ---GMAVCMFMQNTLTRfmrlPLIsvALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTrLVEIIGS 199
Cdd:PRK07468   85 earRLAMMLKALNDLPK----PLI--GRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPY-VVARMGE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 200 RQALKVLSGALKLDSKNALNIGMVEEVLQSSDETKSLEEAqewLKQFIQGPPEVIRALKKSVcsgRELYL---EEALQNE 276
Cdd:PRK07468  158 ANARRVFMSARLFDAEEAVRLGLLSRVVPAERLDAAVEAE---VTPYLSCAPGAVAAAKALV---RALGApidEAVIDAT 231

                         250
                  ....*....|....*...
gi 1099280861 277 RDLLGTVWGGPANLEAIA 294
Cdd:PRK07468  232 IEALADTWETEEAREGIA 249
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
 48-276 3.64e-09

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 56.13  E-value: 3.64e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  48 SIDLQKEDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGsdlnavkslGTPEDGMAVC 127
Cdd:PRK07110    5 VVELREVEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILTGYPNYFATG---------GTQEGLLSLQ 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 128 M-FMQNTLTRFMRLPL---ISV-ALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQA 202
Cdd:PRK07110   76 TgKGTFTEANLYSLALncpIPViAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKLGLALG 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1099280861 203 LKVLSGALKLDSKNALNIGMVEEVLqSSDETksLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNE 276
Cdd:PRK07110  156 QEMLLTARYYRGAELKKRGVPFPVL-PRAEV--LEKALELARSLAEKPRHSLVLLKDHLVADRRRRLPEVIEQE 226
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
 51-233 4.39e-09

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 56.65  E-value: 4.39e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  51 LQKEDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNA-VKSLGTPEDGMAVCMF 129
Cdd:PLN02988   12 LVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAvVRDIEQGNWRLGANFF 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 130 MQNTLTRFMRLPL--ISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLS 207
Cdd:PLN02988   92 SDEYMLNYVMATYskAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLT 171

                         170       180
                  ....*....|....*....|....*.
gi 1099280861 208 GAlKLDSKNALNIGMVEEVLQSSDET 233
Cdd:PLN02988  172 GA-RLDGAEMLACGLATHFVPSTRLT 196
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
 55-279 1.36e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 54.75  E-value: 1.36e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  55 DNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMQ--N 132
Cdd:PRK07260    9 EDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGKVFSVGGDLVEMKRAVDEDDVQSLVKIAElvN 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 133 TLTRFM-RLPLISVALVQGWALGGGAEFTTACDFRLMTpeSKIRFVHK--EMGIIPSWGGTTRLVEIIGSRQALKVLSGA 209
Cdd:PRK07260   89 EISFAIkQLPKPVIMCVDGAVAGAAANMAVAADFCIAS--TKTKFIQAfvGVGLAPDAGGLFLLTRAIGLNRATHLAMTG 166

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1099280861 210 LKLDSKNALNIGMVEEVLQSSDETKSLEEAqewLKQFIQGPPEVIRALK----KSVCSGRELYLEEALQNERDL 279
Cdd:PRK07260  167 EALTAEKALEYGFVYRVAESEKLEKTCEQL---LKKLRRGSSNSYAAIKslvwESFFKGWEDYAKLELALQESL 237
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
 57-276 1.60e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 54.40  E-value: 1.60e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  57 GIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTpEDgmavcmfMQNT--- 133
Cdd:PRK06072    9 GYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEGRAFCVGADLSEFAPDFA-ID-------LRETfyp 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 134 LTRFMRLP-LISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGAlKL 212
Cdd:PRK06072   81 IIREIRFSdKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQRFYEILVLGG-EF 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1099280861 213 DSKNALNIGMVEevlQSSDetkSLEEAQEWLKQFIQGPPEVIRALKKSVcsGRELY--LEEALQNE 276
Cdd:PRK06072  160 TAEEAERWGLLK---ISED---PLSDAEEMANRISNGPFQSYIAAKRMI--NLVLYndLEEFLEYE 217
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
57-272 1.08e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 51.72  E-value: 1.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  57 GIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLN--AVKSLGTPEDGMAVCMFMQnTL 134
Cdd:PRK06023   15 GVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGTEGCFSAGNDMQdfLAAAMGGTSFGSEILDFLI-AL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 135 TRFMRlPLISValVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDS 214
Cdd:PRK06023   94 AEAEK-PIVSG--VDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLALGEGFSA 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1099280861 215 KNALNIGMVEEVLQSSD-ETKSLEEAQEWLKQfiqgPPEVIRALKKSVCSGRELYL----EEA 272
Cdd:PRK06023  171 EAAQEAGLIWKIVDEEAvEAETLKAAEELAAK----PPQALQIARDLMRGPREDILaridEEA 229
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
55-233 1.71e-07

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 51.22  E-value: 1.71e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  55 DNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVcmFMQNTL 134
Cdd:PRK07827   13 DGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTGGTFCAGADLSEAGGGGGDPYDAAV--ARAREM 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 135 TRFMR----LPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGAl 210
Cdd:PRK07827   91 TALLRaiveLPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRAAARYYLTGE- 169

                         170       180
                  ....*....|....*....|...
gi 1099280861 211 KLDSKNALNIGMVEEVLQSSDET 233
Cdd:PRK07827  170 KFGAAEAARIGLVTAAADDVDAA 192
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
134-258 2.34e-07

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 51.18  E-value: 2.34e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 134 LTRFMrlPLISVALVQGWALGGGAEFTTACDFRLMTPE-SKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKL 212
Cdd:PRK08321  130 LIRFM--PKVVIAVVPGWAAGGGHSLHVVCDLTLASREhARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTY 207

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1099280861 213 DSKNALNIGMVEEVLQSSDetksLE-EAQEWLKQFIQGPPEVIRALK 258
Cdd:PRK08321  208 SAEEAHDMGAVNAVVPHAE----LEtEALEWAREINGKSPTAMRMLK 250
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
 63-203 2.46e-07

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 51.52  E-value: 2.46e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  63 LNNPSKMNAFSgVMMLQLLEKVieLENWTEGKGL---IVRGAKNTFSSGSDLNAVKSLgTPEDGMAVCMFMQNTLTRFMR 139
Cdd:PLN02851   57 LNRPSSLNALT-IPMVARLKRL--YESWEENPDIgfvLMKGSGRAFCSGADVVSLYHL-INEGNVEECKLFFENLYKFVY 132

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1099280861 140 L------PliSVALVQGWALGGGAEFTTACDFRLMTpeSKIRFVHKE--MGIIPSWGGT---TRLVEIIGSRQAL 203
Cdd:PLN02851  133 LqgtylkP--NVAIMDGITMGCGAGISIPGMFRVVT--DKTVFAHPEvqMGFHPDAGASyylSRLPGYLGEYLAL 203
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
 40-256 6.19e-07

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 50.18  E-value: 6.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  40 TLQQFPGGSIDLQKEDNGIGILTLNNPSKMNAFSGVMMLQLLEKvieLENWTE---GKGLIVRGAKNTFSSGSDLNAVKS 116
Cdd:PLN02874    3 QQVQNPAEEVVLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEF---LEQWEKddsVELIIIKGAGRAFSAGGDLKMFYD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 117 LGTPEDG-MAVCMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMT-------PESKIRFvHKEMG---IIP 185
Cdd:PLN02874   80 GRESDDScLEVVYRMYWLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTektvfatPEASVGF-HTDCGfsyILS 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1099280861 186 swggttRLVEIIGSRQAlkvLSGAlKLDSKNALNIGMVEEVLQSsdetKSLEEAQEWLKQFIQGPPEVIRA 256
Cdd:PLN02874  159 ------RLPGHLGEYLA---LTGA-RLNGKEMVACGLATHFVPS----EKLPELEKRLLNLNSGDESAVQE 215
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 58-279 8.60e-07

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 49.78  E-value: 8.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  58 IGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA-KNTFSSGSDLNAVKSLGTPEDGMAVCMF------M 130
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAgERAFCAGGDVRALYEAAKAGGGEAGRDFfreeyrL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 131 QNTLTRFMRlPLisVALVQGWALGGGAEFTTACDFRLMT-------PESKIrfvhkemGIIPSWGGT---TRL-VEI--- 196
Cdd:pfam16113  81 NYLIATYPK-PY--VALMDGIVMGGGVGLSVHGSFRVVTertrfamPETAI-------GLFPDVGGSyflSRLpGELgly 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 197 -------IGSRQALK-------VLSGAL-----KLDSKNALNIGMVEEVL-----QSSDETKSLEEAQEWLKQFIQGP-- 250
Cdd:pfam16113 151 laltgarLNGADALAaglathyVPSARLpaleeALAALDWSDPADVDAVLaefaeESDPPPSPLAAHREAIDRCFSADtv 230

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1099280861 251 PEVIRALKK---------------------SVC-------SGRELYLEEALQNERDL 279
Cdd:pfam16113 231 EEIIAALEAeadgdewaaetlktlrkrsptSLKvtlrqlrRGRKLSLAECLRMEYRL 287
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
 51-164 1.50e-06

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 48.40  E-value: 1.50e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  51 LQKEDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDL---NAVKSLGTPEDGMAVC 127
Cdd:PRK08139   14 LREDRDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGKAFCAGHDLkemRAARGLAYFRALFARC 93

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1099280861 128 MFMQNTLTRfMRLPLIsvALVQGWALGGGAEFTTACD 164
Cdd:PRK08139   94 SRVMQAIVA-LPQPVI--ARVHGIATAAGCQLVASCD 127
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
55-288 5.76e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 46.96  E-value: 5.76e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  55 DNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDL------NAVKSLGTPEDGM--AV 126
Cdd:PRK08272   17 TGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAGKGFCAGYDLsayaegSSSGGGGGAYPGKrqAV 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 127 C---------MFMQNTLTRFMRLPLI-------SVALVQGWALGGGAEFTTACDFRLMTPESKIrfvhkemGIIPS--WG 188
Cdd:PRK08272   97 NhlpddpwdpMIDYQMMSRFVRGFMSlwhahkpTVAKVHGYCVAGGTDIALHCDQVIAADDAKI-------GYPPTrvWG 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 189 GTT------RLveiiGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSDetksLEEAQEWLKQFIQG-PPEVIRALKKSV 261
Cdd:PRK08272  170 VPAtgmwayRL----GPQRAKRLLFTGDCITGAQAAEWGLAVEAVPPEE----LDERTERLVERIAAvPVNQLAMVKLAV 241

                         250       260
                  ....*....|....*....|....*..
gi 1099280861 262 CSGRELYLEEALQnerdLLGTVWGGPA 288
Cdd:PRK08272  242 NSALLQQGVATSQ----MLATVFDGIA 264
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
45-279 1.07e-05

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 45.84  E-value: 1.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  45 PGGSIDLQKEDNgIGILTLNNPSkMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLnavKSLGTPEDGm 124
Cdd:PRK06495    2 MMSQLKLEVSDH-VAVVTLDNPP-VNALSRELRDELIAVFDEISERPDVRVVVLTGAGKVFCAGADL---KGRPDVIKG- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 125 AVCMFMQNTLTRFMRLPLIS-----VALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIpswGGTTRLVEIIG- 198
Cdd:PRK06495   76 PGDLRAHNRRTRECFHAIREcakpvIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGLA---GGGKHAMRLFGh 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 199 SRQALKVLSGaLKLDSKNALNIGMVEEVLqSSDETksLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERD 278
Cdd:PRK06495  153 SLTRRMMLTG-YRVPAAELYRRGVIEACL-PPEEL--MPEAMEIAREIASKSPLATRLAKDALNTIENMSLRDGYRYEQD 228


                  .
gi 1099280861 279 L 279
Cdd:PRK06495  229 I 229
PLN02921 PLN02921
naphthoate synthase
 57-260 1.09e-05

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 46.32  E-value: 1.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  57 GIGILTLNNPSKMNAFSGVMMLQLLEKvieLENWTEGK--GLIVRGAKNT--FSSGSDlNAVKSLG--TPEDGMAvcmfM 130
Cdd:PLN02921   76 GIAKITINRPERRNAFRPRTVKELQRA---FNDARDDSsvGVIILTGKGTkaFCSGGD-QAVRGKDgyVGPDDAG----R 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 131 QNTLTRFM---RLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLS 207
Cdd:PLN02921  148 LNVLDLQIqirRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMWF 227

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1099280861 208 GALKLDSKNALNIGMVEEVLQSSDetksLE-EAQEWLKQFIQGPPEVIRALKKS 260
Cdd:PLN02921  228 LARFYTASEALKMGLVNTVVPLDE----LEgETVKWCREILRNSPTAIRVLKSA 277
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
53-186 1.16e-05

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 45.83  E-value: 1.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  53 KEDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENwtEGKGLIVRGAKNTFSSGSDLNAVKSLgtPEDGMAVcMFMQN 132
Cdd:PRK07112    9 RQQGDVCFLQLHRPEAQNTINDRLIAECMDVLDRCEH--AATIVVLEGLPEVFCFGADFSAIAEK--PDAGRAD-LIDAE 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 133 TL----TRFMRLPLISVALVQGWALGGGAEFTTACDfrLMTPESKIRFVHKEM--GIIPS 186
Cdd:PRK07112   84 PLydlwHRLATGPYVTIAHVRGKVNAGGIGFVAASD--IVIADETAPFSLSELlfGLIPA 141
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
 51-258 2.08e-05

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 45.27  E-value: 2.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  51 LQKEDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA-KNTFSSGSDLNaVKSLGTPEDGMAVCMF 129
Cdd:PRK07396   16 LYKSADGIAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAgDKAFCSGGDQK-VRGYGGYVDDDGVPRL 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 130 MQNTLTRFMR-LPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSG 208
Cdd:PRK07396   95 NVLDLQRLIRtCPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGYGASYLARIVGQKKAREIWFL 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1099280861 209 ALKLDSKNALNIGMVEEVLQSSDetksLE-EAQEWLKQFIQGPPEVIRALK 258
Cdd:PRK07396  175 CRQYDAQEALDMGLVNTVVPLAD----LEkETVRWCREMLQNSPMALRCLK 221
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
 133-210 3.23e-05

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 44.52  E-value: 3.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 133 TLTRFMRLPLISVALVQGWALGGGAEFTTACDF-------RLMTPEskIRFvhkemGIIPSWGGTTRLVEIIGSRQALK- 204
Cdd:PRK08788  113 AFHRGFGAGAISIALVQGDALGGGFEAALSHHTiiaergaKMGFPE--ILF-----NLFPGMGAYSFLARRVGPKLAEEl 185


                  ....*.
gi 1099280861 205 VLSGAL 210
Cdd:PRK08788  186 ILSGKL 191
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
 63-256 4.31e-05

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 44.67  E-value: 4.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  63 LNNPSKMNAFSGVMMLQLlEKVieLENWTEGKGL---IVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMqNTLTRFMR 139
Cdd:PLN02157   52 LNRPPALNALTTHMGYRL-QKL--YKNWEEDPNIgfvMMKGSGRAFCAGGDIVSLYHLRKRGSPDAIREFF-SSLYSFIY 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 140 L------PliSVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGaLKLD 213
Cdd:PLN02157  128 LlgtylkP--HVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLPGRLGEYLGLTG-LKLS 204

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1099280861 214 SKNALNIGMVEEVLQsSDETKSLEEAqewLKQFIQGPPEVIRA 256
Cdd:PLN02157  205 GAEMLACGLATHYIR-SEEIPVMEEQ---LKKLLTDDPSVVES 243
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
48-260 5.72e-04

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 40.77  E-value: 5.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  48 SIDLQKEDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVC 127
Cdd:PRK07327   12 ALRFDRPPPGVLEIVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEGKAFSAGGDLALVEEMADDFEVRARV 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 128 MFMQNTLTRFM---RLPLISValVQGWALGGGAEFTTACDFRLMTPESKIRfvhkemgiipswGGTTRLVEIIGSRQAL- 203
Cdd:PRK07327   92 WREARDLVYNVincDKPIVSA--IHGPAVGAGLVAALLADISIAAKDARII------------DGHTRLGVAAGDHAAIv 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1099280861 204 -KVLSGALK----------LDSKNALNIGMVEEVLqssDETKSLEEAQEWLKQFIQGPPEVIRALKKS 260
Cdd:PRK07327  158 wPLLCGMAKakyylllcepVSGEEAERIGLVSLAV---DDDELLPKALEVAERLAAGSQTAIRWTKYA 222
PLN02267 PLN02267
enoyl-CoA hydratase/isomerase family protein
 51-233 1.23e-03

enoyl-CoA hydratase/isomerase family protein


Pssm-ID: 215151  Cd Length: 239  Bit Score: 39.70  E-value: 1.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  51 LQKEDNgIGILTLN-------NPSKMNAfsgvmMLQLLEKVieLENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDG 123
Cdd:PLN02267    4 LEKRGN-LFILTLTgdgehrlNPTLIDS-----IRSALRQV--KSQATPGSVLITTAEGKFFSNGFDLAWAQAAGSAPSR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861 124 MAV-CMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVhKEMGI---IPSWgGTTRLVEIIGS 199
Cdd:PLN02267   76 LHLmVAKLRPLVADLISLPMPTIAAVTGHASAAGFILALSHDYVLMRKDRGVLYM-SEVDIglpLPDY-FMALLRAKIGS 153

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1099280861 200 RQALK--VLSGAlKLDSKNALNIGMVEEVLQSSDET 233
Cdd:PLN02267  154 PAARRdvLLRAA-KLTAEEAVEMGIVDSAHDSAEET 188
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
51-188 1.52e-03

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 39.55  E-value: 1.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099280861  51 LQKEDNGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDL--------NAVKSLGTPED 122
Cdd:PRK12478    8 LYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAGRAFSGGYDFgggfqhwgEAMMTDGRWDP 87

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1099280861 123 GMAVCMFMQNTLT---RFM---RLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMgiipsWG 188
Cdd:PRK12478   88 GKDFAMVTARETGptqKFMaiwRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYSRM-----WG 154
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH