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Conserved domains on  [gi|1062906951|ref|XP_017950117|]
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protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 isoform X1 [Xenopus tropicalis]

Protein Classification

glycosyltransferase family 61 protein( domain architecture ID 79050)

glycosyltransferase family 61 protein may function as a glycosyltransferase, similar to Mus musculus protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glyco_transf_61 super family cl15705
Glycosyltransferase 61; This family represents the Glycosyltransferase Family 61. Members in ...
 288-389 7.89e-16

Glycosyltransferase 61; This family represents the Glycosyltransferase Family 61. Members in this family are further processed into a mature form. It includes O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGnT2, also known as AGO61 or EOGLT) and EGF domain-specific O-linked N-acetylglucosamine transferase (EOGT). This family also includes plant beta-1,2-xylosyltransferases.


The actual alignment was detected with superfamily member COG4421:

Pssm-ID: 472831  Cd Length: 258  Bit Score: 77.69  E-value: 7.89e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062906951 288 VLFSR--SMNRLIVNEAELLLALAQE-FQmktiTVSLEDHSFADIVRLISNATMLVSMHGAQLITSLFLPKGAIVVELFp 364
Cdd:COG4421   127 IYISRrdASRRRILNEEELEALLEKYgFE----IVDPEELSFAEQIALFAEAEVIVGPHGAGLTNLVFCRPGTKVIELF- 201

                          90       100
                  ....*....|....*....|....*..
gi 1062906951 365 ygvnPEHYTP--YKTLSTLPGMELQYV 389
Cdd:COG4421   202 ----PPGYVNpyFWLLAALLGLRYYYL 224
 
Name Accession Description Interval E-value
COG4421 COG4421
Capsular polysaccharide biosynthesis protein [Cell wall/membrane/envelope biogenesis];
288-389 7.89e-16

Capsular polysaccharide biosynthesis protein [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443536  Cd Length: 258  Bit Score: 77.69  E-value: 7.89e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062906951 288 VLFSR--SMNRLIVNEAELLLALAQE-FQmktiTVSLEDHSFADIVRLISNATMLVSMHGAQLITSLFLPKGAIVVELFp 364
Cdd:COG4421   127 IYISRrdASRRRILNEEELEALLEKYgFE----IVDPEELSFAEQIALFAEAEVIVGPHGAGLTNLVFCRPGTKVIELF- 201

                          90       100
                  ....*....|....*....|....*..
gi 1062906951 365 ygvnPEHYTP--YKTLSTLPGMELQYV 389
Cdd:COG4421   202 ----PPGYVNpyFWLLAALLGLRYYYL 224
Glyco_transf_61 pfam04577
Glycosyltransferase 61; This family represents the Glycosyltransferase Family 61. Members in ...
 287-360 6.60e-14

Glycosyltransferase 61; This family represents the Glycosyltransferase Family 61. Members in this family are further processed into a mature form. It includes O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGnT2, also known as AGO61 or EOGLT) and EGF domain-specific O-linked N-acetylglucosamine transferase (EOGT). This family also includes plant beta-1,2-xylosyltransferases.


Pssm-ID: 428020  Cd Length: 124  Bit Score: 68.49  E-value: 6.60e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1062906951 287 IVLFSR--SMNRLIVNEAELLLALAQEFqmKTITVSLEDHSFADIVRLISNATMLVSMHGAQLITSLFLPKGAIVV 360
Cdd:pfam04577  51 YVYISRgdARRRRILNEDELEAALKKEY--GFEIVDPEKLSLEEQVKLFSSAKVIVGPHGSGLTNSIFMPPGTVVV 124
 
Name Accession Description Interval E-value
COG4421 COG4421
Capsular polysaccharide biosynthesis protein [Cell wall/membrane/envelope biogenesis];
288-389 7.89e-16

Capsular polysaccharide biosynthesis protein [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443536  Cd Length: 258  Bit Score: 77.69  E-value: 7.89e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062906951 288 VLFSR--SMNRLIVNEAELLLALAQE-FQmktiTVSLEDHSFADIVRLISNATMLVSMHGAQLITSLFLPKGAIVVELFp 364
Cdd:COG4421   127 IYISRrdASRRRILNEEELEALLEKYgFE----IVDPEELSFAEQIALFAEAEVIVGPHGAGLTNLVFCRPGTKVIELF- 201

                          90       100
                  ....*....|....*....|....*..
gi 1062906951 365 ygvnPEHYTP--YKTLSTLPGMELQYV 389
Cdd:COG4421   202 ----PPGYVNpyFWLLAALLGLRYYYL 224
Glyco_transf_61 pfam04577
Glycosyltransferase 61; This family represents the Glycosyltransferase Family 61. Members in ...
 287-360 6.60e-14

Glycosyltransferase 61; This family represents the Glycosyltransferase Family 61. Members in this family are further processed into a mature form. It includes O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGnT2, also known as AGO61 or EOGLT) and EGF domain-specific O-linked N-acetylglucosamine transferase (EOGT). This family also includes plant beta-1,2-xylosyltransferases.


Pssm-ID: 428020  Cd Length: 124  Bit Score: 68.49  E-value: 6.60e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1062906951 287 IVLFSR--SMNRLIVNEAELLLALAQEFqmKTITVSLEDHSFADIVRLISNATMLVSMHGAQLITSLFLPKGAIVV 360
Cdd:pfam04577  51 YVYISRgdARRRRILNEDELEAALKKEY--GFEIVDPEKLSLEEQVKLFSSAKVIVGPHGSGLTNSIFMPPGTVVV 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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