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Conserved domains on  [gi|1062958688|ref|XP_017895740|]
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PREDICTED: zinc finger protein 768 [Capra hircus]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472953)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  22803940|11361095|11179890|12665246|10940247
SCOP:  4003583

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
297-525 5.33e-09

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.55  E-value: 5.33e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 297 LIQHQRIHTGEKPYKCEVCSKAFSQSSDLIKHQRTHTGERPYKCPRCG------KAFADSSYLLRHQRTHSGQ-KPYKCP 369
Cdd:COG5048   214 SSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPrsslptASSQSSSPNESDSSSEKGFsLPIKSK 293

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 370 HCGKAFGDSSYLLRHQRTHSHE----RPYSCPE--CGKCYSQNSSLRSHQRVHTGQRPFSC--GICGKSFSQRSALIPHA 441
Cdd:COG5048   294 QCNISFSRSSPLTRHLRSVNHSgeslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQ 373

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 442 RSHAR-----EKPFKC--PECGKRFGQSSVLAIHARTHLPGRTYSC--PDCGKTFNRSSTLIQHQRSHTGERPYRCavCG 512
Cdd:COG5048   374 SLQQYkdlknDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCknPPCSKSFNRHYNLIPHKKIHTNHAPLLC--SI 451

                         250
                  ....*....|...
gi 1062958688 513 KGFCRSSTLLQHH 525
Cdd:COG5048   452 LKSFRRDLDLSNH 464
PRK10263 super family cl35903
DNA translocase FtsK; Provisional
 17-182 1.21e-07

DNA translocase FtsK; Provisional


The actual alignment was detected with superfamily member PRK10263:

Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 54.71  E-value: 1.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688   17 SPDEMGSPEGSLKGNMSENEEEEISQQEGTGDYEVEEIsfgLEPQSPGFGPQSPEFEPQSPRFEP------ESPGFESRS 90
Cdd:PRK10263   335 APVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPV---IAPAPEGYPQQSQYAQPAVQYNEPlqqpvqPQQPYYAPA 411

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688   91 PGFVPPSPEFAPrSPESDSQSPDFEPQSPRYEPQSPGY-EPKSPGYEPRsPGYEPKSPGYEPRSPGYESQSPRYEPQSPG 169
Cdd:PRK10263   412 AEQPAQQPYYAP-APEQPAQQPYYAPAPEQPVAGNAWQaEEQQSTFAPQ-STYQTEQTYQQPAAQEPLYQQPQPVEQQPV 489

                          170
                   ....*....|...
gi 1062958688  170 YEPQnPEFKTQSP 182
Cdd:PRK10263   490 VEPE-PVVEETKP 501
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 534-556 4.14e-06

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


:

Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 43.44  E-value: 4.14e-06
                          10        20
                  ....*....|....*....|...
gi 1062958688 534 YKCDDCGKAFSQSSDLIRHQRTH 556
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
297-525 5.33e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.55  E-value: 5.33e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 297 LIQHQRIHTGEKPYKCEVCSKAFSQSSDLIKHQRTHTGERPYKCPRCG------KAFADSSYLLRHQRTHSGQ-KPYKCP 369
Cdd:COG5048   214 SSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPrsslptASSQSSSPNESDSSSEKGFsLPIKSK 293

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 370 HCGKAFGDSSYLLRHQRTHSHE----RPYSCPE--CGKCYSQNSSLRSHQRVHTGQRPFSC--GICGKSFSQRSALIPHA 441
Cdd:COG5048   294 QCNISFSRSSPLTRHLRSVNHSgeslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQ 373

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 442 RSHAR-----EKPFKC--PECGKRFGQSSVLAIHARTHLPGRTYSC--PDCGKTFNRSSTLIQHQRSHTGERPYRCavCG 512
Cdd:COG5048   374 SLQQYkdlknDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCknPPCSKSFNRHYNLIPHKKIHTNHAPLLC--SI 451

                         250
                  ....*....|...
gi 1062958688 513 KGFCRSSTLLQHH 525
Cdd:COG5048   452 LKSFRRDLDLSNH 464
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 17-182 1.21e-07

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 54.71  E-value: 1.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688   17 SPDEMGSPEGSLKGNMSENEEEEISQQEGTGDYEVEEIsfgLEPQSPGFGPQSPEFEPQSPRFEP------ESPGFESRS 90
Cdd:PRK10263   335 APVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPV---IAPAPEGYPQQSQYAQPAVQYNEPlqqpvqPQQPYYAPA 411

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688   91 PGFVPPSPEFAPrSPESDSQSPDFEPQSPRYEPQSPGY-EPKSPGYEPRsPGYEPKSPGYEPRSPGYESQSPRYEPQSPG 169
Cdd:PRK10263   412 AEQPAQQPYYAP-APEQPAQQPYYAPAPEQPVAGNAWQaEEQQSTFAPQ-STYQTEQTYQQPAAQEPLYQQPQPVEQQPV 489

                          170
                   ....*....|...
gi 1062958688  170 YEPQnPEFKTQSP 182
Cdd:PRK10263   490 VEPE-PVVEETKP 501
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 534-556 4.14e-06

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 43.44  E-value: 4.14e-06
                          10        20
                  ....*....|....*....|...
gi 1062958688 534 YKCDDCGKAFSQSSDLIRHQRTH 556
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
352-375 4.25e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.51  E-value: 4.25e-06
                          10        20
                  ....*....|....*....|....
gi 1062958688 352 YLLRHQRTHSGQKPYKCPHCGKAF 375
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 420-471 3.39e-05

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 42.16  E-value: 3.39e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1062958688 420 RPFsCGICGKSFSQRSALIpharSHAREKPFKCPECGKRFGQSSVLAIHART 471
Cdd:cd20908     1 KPW-CYYCDREFDDEKILI----QHQKAKHFKCHICHKKLYTAGGLAVHCLQ 47
PHA00733 PHA00733
hypothetical protein
 309-356 1.13e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 39.09  E-value: 1.13e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1062958688 309 PYKCEVCSKAFSQSSDLIKHQR--THTgerpYKCPRCGKAFADSSYLLRH 356
Cdd:PHA00733   73 PYVCPLCLMPFSSSVSLKQHIRytEHS----KVCPVCGKEFRNTDSTLDH 118
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 74-210 2.13e-03

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 40.91  E-value: 2.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688  74 PQSPRfEPESPGFESRSPGFVP-PSPEFAPRSPESDSQSPDFEPQSPRYEPQ-SPGYEPKSPGYEPrspgyEPKSPGYEP 151
Cdd:NF033839  281 QDTPK-EPGNKKPSAPKPGMQPsPQPEKKEVKPEPETPKPEVKPQLEKPKPEvKPQPEKPKPEVKP-----QLETPKPEV 354

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 152 RsPGYESQSPRYEPQSPGYEPQ-NPEFKTQSPEFEAESSKFQegAEILLNPEEKNPLSIP 210
Cdd:NF033839  355 K-PQPEKPKPEVKPQPEKPKPEvKPQPETPKPEVKPQPEKPK--PEVKPQPEKPKPEVKP 411
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 60-206 2.83e-03

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 40.52  E-value: 2.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688  60 PQSPGFGPQSPEFEPQSPRFEPE-SPGFESRSPGFVP----PSPEFAPR--------SPESDSQSPDFEPQ----SPRYE 122
Cdd:NF033839  309 EVKPEPETPKPEVKPQLEKPKPEvKPQPEKPKPEVKPqletPKPEVKPQpekpkpevKPQPEKPKPEVKPQpetpKPEVK 388

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 123 PQSPGYEPK-SPGYEPRSPGYEPKSPGYEPR-SPGYESQSPRYEPQSPGYEPQ-NPEFKTQSPEFEAESSKfqEGAEILL 199
Cdd:NF033839  389 PQPEKPKPEvKPQPEKPKPEVKPQPEKPKPEvKPQPEKPKPEVKPQPEKPKPEvKPQPEKPKPEVKPQPET--PKPEVKP 466


                  ....*..
gi 1062958688 200 NPEEKNP 206
Cdd:NF033839  467 QPEKPKP 473
ZnF_C2H2 smart00355
zinc finger;
366-388 3.09e-03

zinc finger;


Pssm-ID: 197676  Cd Length: 23  Bit Score: 35.13  E-value: 3.09e-03
                           10        20
                   ....*....|....*....|...
gi 1062958688  366 YKCPHCGKAFGDSSYLLRHQRTH 388
Cdd:smart00355   1 YRCPECGKVFKSKSALREHMRTH 23
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 59-206 5.49e-03

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 39.37  E-value: 5.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688  59 EPQSPGFGPQ-SPEFEPQSPRFEPESPGFESRsPGFVPPSPEFAPR--------SPESDSQSPDFEPQ----SPRYEPQS 125
Cdd:NF033839  291 KPSAPKPGMQpSPQPEKKEVKPEPETPKPEVK-PQLEKPKPEVKPQpekpkpevKPQLETPKPEVKPQpekpKPEVKPQP 369

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 126 PGYEPKSPGyEPRSPGYEPKSPGYEPR---SPGYESQSPRYEPQ--------SPGYEPQNPEFKTQSPEFEAESSKFQEG 194
Cdd:NF033839  370 EKPKPEVKP-QPETPKPEVKPQPEKPKpevKPQPEKPKPEVKPQpekpkpevKPQPEKPKPEVKPQPEKPKPEVKPQPEK 448

                         170
                  ....*....|..
gi 1062958688 195 AEILLNPEEKNP 206
Cdd:NF033839  449 PKPEVKPQPETP 460
ZnF_C2H2 smart00355
zinc finger;
534-556 6.72e-03

zinc finger;


Pssm-ID: 197676  Cd Length: 23  Bit Score: 34.36  E-value: 6.72e-03
                           10        20
                   ....*....|....*....|...
gi 1062958688  534 YKCDDCGKAFSQSSDLIRHQRTH 556
Cdd:smart00355   1 YRCPECGKVFKSKSALREHMRTH 23
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
297-525 5.33e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.55  E-value: 5.33e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 297 LIQHQRIHTGEKPYKCEVCSKAFSQSSDLIKHQRTHTGERPYKCPRCG------KAFADSSYLLRHQRTHSGQ-KPYKCP 369
Cdd:COG5048   214 SSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPrsslptASSQSSSPNESDSSSEKGFsLPIKSK 293

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 370 HCGKAFGDSSYLLRHQRTHSHE----RPYSCPE--CGKCYSQNSSLRSHQRVHTGQRPFSC--GICGKSFSQRSALIPHA 441
Cdd:COG5048   294 QCNISFSRSSPLTRHLRSVNHSgeslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQ 373

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 442 RSHAR-----EKPFKC--PECGKRFGQSSVLAIHARTHLPGRTYSC--PDCGKTFNRSSTLIQHQRSHTGERPYRCavCG 512
Cdd:COG5048   374 SLQQYkdlknDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCknPPCSKSFNRHYNLIPHKKIHTNHAPLLC--SI 451

                         250
                  ....*....|...
gi 1062958688 513 KGFCRSSTLLQHH 525
Cdd:COG5048   452 LKSFRRDLDLSNH 464
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
281-556 2.64e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 56.24  E-value: 2.64e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 281 PNICGICGKSFGRGSTLIQHQRIHTGEKPYKCEV--CSKAFSQSSDLIKHQRTHTGERPYKC--PRCGKAFADSSYLLRH 356
Cdd:COG5048    33 PDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNskSLPLSNSKASSSSLSS 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 357 QRTHSgQKPYKCPHCGKAFGDSSYLLRHQRTHSHERPYSCPEC----------------------GKCYSQNSSLRSHQR 414
Cdd:COG5048   113 SSSNS-NDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnsssvntpqsnslhpplpanslSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 415 VHTGQRPFSCGICGKSFSQRSALIPHARSHAREKPFKCPECGKRFGQSSVLAIHARTHLPGRTYSCPDCGKTF--NRSST 492
Cdd:COG5048   192 VSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSlpTASSQ 271

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1062958688 493 LIQHQRSHTGER-----PYRCAVCGKGFCRSSTLLQH--HRVHSGE--RPYKCD--DCGKAFSQSSDLIRHQRTH 556
Cdd:COG5048   272 SSSPNESDSSSEkgfslPIKSKQCNISFSRSSPLTRHlrSVNHSGEslKPFSCPysLCGKLFSRNDALKRHILLH 346
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 17-182 1.21e-07

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 54.71  E-value: 1.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688   17 SPDEMGSPEGSLKGNMSENEEEEISQQEGTGDYEVEEIsfgLEPQSPGFGPQSPEFEPQSPRFEP------ESPGFESRS 90
Cdd:PRK10263   335 APVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPV---IAPAPEGYPQQSQYAQPAVQYNEPlqqpvqPQQPYYAPA 411

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688   91 PGFVPPSPEFAPrSPESDSQSPDFEPQSPRYEPQSPGY-EPKSPGYEPRsPGYEPKSPGYEPRSPGYESQSPRYEPQSPG 169
Cdd:PRK10263   412 AEQPAQQPYYAP-APEQPAQQPYYAPAPEQPVAGNAWQaEEQQSTFAPQ-STYQTEQTYQQPAAQEPLYQQPQPVEQQPV 489

                          170
                   ....*....|...
gi 1062958688  170 YEPQnPEFKTQSP 182
Cdd:PRK10263   490 VEPE-PVVEETKP 501
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 534-556 4.14e-06

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 43.44  E-value: 4.14e-06
                          10        20
                  ....*....|....*....|...
gi 1062958688 534 YKCDDCGKAFSQSSDLIRHQRTH 556
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
352-375 4.25e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.51  E-value: 4.25e-06
                          10        20
                  ....*....|....*....|....
gi 1062958688 352 YLLRHQRTHSGQKPYKCPHCGKAF 375
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
zf-H2C2_2 pfam13465
Zinc-finger double domain;
297-321 6.74e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.74  E-value: 6.74e-06
                          10        20
                  ....*....|....*....|....*
gi 1062958688 297 LIQHQRIHTGEKPYKCEVCSKAFSQ 321
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
dnaA PRK14086
chromosomal replication initiator protein DnaA;
59-176 1.77e-05

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 47.51  E-value: 1.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688  59 EPQSPGFGPQSPEfEPQSPRFEPES-PGFESRSPGFVPPSPEFAPRSPESDSQSPDFEPQS-----PRyEPQSPGYEPKS 132
Cdd:PRK14086   94 EPAPPPPHARRTS-EPELPRPGRRPyEGYGGPRADDRPPGLPRQDQLPTARPAYPAYQQRPepgawPR-AADDYGWQQQR 171

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1062958688 133 PGYEPRSPGYEPKS--PGYEPRSPGYESQSPRYEPQSPGYEPQNPE 176
Cdd:PRK14086  172 LGFPPRAPYASPASyaPEQERDREPYDAGRPEYDQRRRDYDHPRPD 217
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 306-390 1.89e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 47.41  E-value: 1.89e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 306 GEKPYKCEV--CSKAFSQSSDLiKHQRTHTGERPYKCPRCGKafadssylLRHQRTHSGQKPYKCPHCGKAFGDSSYLLR 383
Cdd:COG5189   346 DGKPYKCPVegCNKKYKNQNGL-KYHMLHGHQNQKLHENPSP--------EKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  ....*..
gi 1062958688 384 HqRTHSH 390
Cdd:COG5189   417 H-RKHSH 422
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 366-388 2.04e-05

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 41.52  E-value: 2.04e-05
                          10        20
                  ....*....|....*....|...
gi 1062958688 366 YKCPHCGKAFGDSSYLLRHQRTH 388
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 59-211 2.44e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 47.39  E-value: 2.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688   59 EPQSPGFGPQSPEFEPQSPRFEPESpgfesrSPGFVPPSPEFAPrSPESDSQSPDF-EPQSPRYEPQSPGYEPKSPGYEP 137
Cdd:PRK10263   338 EPVTQTPPVASVDVPPAQPTVAWQP------VPGPQTGEPVIAP-APEGYPQQSQYaQPAVQYNEPLQQPVQPQQPYYAP 410

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688  138 RSPGyEPKSPGY----------------------------EPRSPGYESQsPRYEPQSPGYEPQNPEFKTQSPEFEAESS 189
Cdd:PRK10263   411 AAEQ-PAQQPYYapapeqpaqqpyyapapeqpvagnawqaEEQQSTFAPQ-STYQTEQTYQQPAAQEPLYQQPQPVEQQP 488

                          170       180
                   ....*....|....*....|..
gi 1062958688  190 KFQEGAEIllnpEEKNPLSIPL 211
Cdd:PRK10263   489 VVEPEPVV----EETKPARPPL 506
zf-H2C2_2 pfam13465
Zinc-finger double domain;
324-348 2.93e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.82  E-value: 2.93e-05
                          10        20
                  ....*....|....*....|....*
gi 1062958688 324 DLIKHQRTHTGERPYKCPRCGKAFA 348
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 478-500 2.93e-05

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 40.75  E-value: 2.93e-05
                          10        20
                  ....*....|....*....|...
gi 1062958688 478 YSCPDCGKTFNRSSTLIQHQRSH 500
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 420-471 3.39e-05

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 42.16  E-value: 3.39e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1062958688 420 RPFsCGICGKSFSQRSALIpharSHAREKPFKCPECGKRFGQSSVLAIHART 471
Cdd:cd20908     1 KPW-CYYCDREFDDEKILI----QHQKAKHFKCHICHKKLYTAGGLAVHCLQ 47
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 338-360 4.13e-05

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 40.36  E-value: 4.13e-05
                          10        20
                  ....*....|....*....|...
gi 1062958688 338 YKCPRCGKAFADSSYLLRHQRTH 360
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 310-332 5.02e-05

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 40.36  E-value: 5.02e-05
                          10        20
                  ....*....|....*....|...
gi 1062958688 310 YKCEVCSKAFSQSSDLIKHQRTH 332
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 394-416 6.11e-05

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 39.98  E-value: 6.11e-05
                          10        20
                  ....*....|....*....|...
gi 1062958688 394 YSCPECGKCYSQNSSLRSHQRVH 416
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 391-472 7.56e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 45.48  E-value: 7.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 391 ERPYSCP--ECGKCYSQNSSLRSHqRVHtgqrpfscGICGKSFSQRSALIPHARSHAREKPFKCPECGKRFGQSSVLAIH 468
Cdd:COG5189   347 GKPYKCPveGCNKKYKNQNGLKYH-MLH--------GHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYH 417


                  ....
gi 1062958688 469 aRTH 472
Cdd:COG5189   418 -RKH 420
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 334-417 9.48e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 45.09  E-value: 9.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 334 GERPYKCP--RCGKAFAdSSYLLRHQRTHSgqkpykcpHCGKAFGDSSYLLRHQRTHSHERPYSCPECGKCYSQNSSLRS 411
Cdd:COG5189   346 DGKPYKCPveGCNKKYK-NQNGLKYHMLHG--------HQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  ....*.
gi 1062958688 412 HqRVHT 417
Cdd:COG5189   417 H-RKHS 421
zf-H2C2_2 pfam13465
Zinc-finger double domain;
408-433 1.12e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.28  E-value: 1.12e-04
                          10        20
                  ....*....|....*....|....*.
gi 1062958688 408 SLRSHQRVHTGQRPFSCGICGKSFSQ 433
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
521-545 1.21e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.28  E-value: 1.21e-04
                          10        20
                  ....*....|....*....|....*
gi 1062958688 521 LLQHHRVHSGERPYKCDDCGKAFSQ 545
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
323-556 1.78e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 44.30  E-value: 1.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 323 SDLIKHQRTHTGERPYKCPRCGKAFADSSYLLRHQRTHSGQKPYKCPHCGKAFGDSSYLLRHQRTHSHERPYSCPECGKC 402
Cdd:COG5048   184 LSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRS 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 403 YSQ--NSSLRSHQRVHTGQR-----PFSCGICGKSFSQRSALIPHARS--HARE--KPFKCPE--CGKRFGQSSVLAIHA 469
Cdd:COG5048   264 SLPtaSSQSSSPNESDSSSEkgfslPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHI 343

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 470 RTHLPGRTYSCP--DCGKTFNRSST-----LIQHQRSHTGERPYRCAV--CGKGFCRSSTLLQHHRVHSGERPY--KCDD 538
Cdd:COG5048   344 LLHTSISPAKEKllNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPYncKNPP 423

                         250
                  ....*....|....*...
gi 1062958688 539 CGKAFSQSSDLIRHQRTH 556
Cdd:COG5048   424 CSKSFNRHYNLIPHKKIH 441
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 16-169 1.93e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.39  E-value: 1.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688   16 QSPDEMGSPEGSLKGNMSENEEEEISQQEGTGDYEVEEISFGLEPqSPGFGPQSPEFEPQSPRFEPESPGfeSRSPGFVP 95
Cdd:PHA03307   234 ASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGP-SSRPGPASSSSSPRERSPSPSPSS--PGSGPAPS 310

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1062958688   96 PSP--EFAPRSPESDSQSPDFEPQSPRYEPQSPGYEPKSPGYEPRSPGYEPKSPgyePRSPGYESQSPRYEPQSPG 169
Cdd:PHA03307   311 SPRasSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSS---PRKRPRPSRAPSSPAASAG 383
zf-H2C2_2 pfam13465
Zinc-finger double domain;
493-515 2.96e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 2.96e-04
                          10        20
                  ....*....|....*....|...
gi 1062958688 493 LIQHQRSHTGERPYRCAVCGKGF 515
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSF 24
dnaA PRK14086
chromosomal replication initiator protein DnaA;
60-185 4.98e-04

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 42.89  E-value: 4.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688  60 PQSPGFGPQSPEFEPQSPRFEPESPGFESRS-PGFVPPSPEFAPRSPESDSQSPDFEPQSPRYEPQS-PGYEPKspgyEP 137
Cdd:PRK14086   87 TVDPSAGEPAPPPPHARRTSEPELPRPGRRPyEGYGGPRADDRPPGLPRQDQLPTARPAYPAYQQRPePGAWPR----AA 162

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1062958688 138 RSPGYEPKSPGYEPRSPGYESQSPRYEPQ--SPGYEPQNPEFKTQSPEFE 185
Cdd:PRK14086  163 DDYGWQQQRLGFPPRAPYASPASYAPEQErdREPYDAGRPEYDQRRRDYD 212
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 483-528 5.98e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.69  E-value: 5.98e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1062958688 483 CGKTFNRSSTLIQHQRSHTgerpYRCAVCGKGFcRSSTLLQHH--RVH 528
Cdd:cd20908     7 CDREFDDEKILIQHQKAKH----FKCHICHKKL-YTAGGLAVHclQVH 49
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
320-389 6.14e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 42.38  E-value: 6.14e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1062958688 320 SQSSDLIKHQRTHTGE----RPYKCPRCGKAFADSSYLLRHQRTHSGQKPYKCPH--CGKAFGDSSYLLRHQRTHS 389
Cdd:COG5048    12 NNSVLSSTPKSTLKSLsnapRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHH 87
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 364-416 9.39e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.31  E-value: 9.39e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1062958688 364 KPYkCPHCGKAFGDSSYLLRHQRTHsHerpYSCPECGKCYSQNSSLRSH-QRVH 416
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAK-H---FKCHICHKKLYTAGGLAVHcLQVH 49
PHA00733 PHA00733
hypothetical protein
 309-356 1.13e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 39.09  E-value: 1.13e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1062958688 309 PYKCEVCSKAFSQSSDLIKHQR--THTgerpYKCPRCGKAFADSSYLLRH 356
Cdd:PHA00733   73 PYVCPLCLMPFSSSVSLKQHIRytEHS----KVCPVCGKEFRNTDSTLDH 118
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 72-204 1.23e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 41.98  E-value: 1.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688  72 FEPQSPRFEPESPGFESRSPGFVPP----SPEFaPRSPESDSQSPDFEPQSPRYEPQSPGYEPKSPGYEPRSPGY----- 142
Cdd:PTZ00449  699 FESILKETLPETPGTPFTTPRPLPPklprDEEF-PFEPIGDPDAEQPDDIEFFTPPEEERTFFHETPADTPLPDIlaeef 777

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1062958688 143 ----------EPKSPGYEPRSPGyesqspRYEPQSPGYEPQNPEFKTQSPEFEAESSKFQ-EGAEILLNPEEK 204
Cdd:PTZ00449  778 keedihaetgEPDEAMKRPDSPS------EHEDKPPGDHPSLPKKRHRLDGLALSTTDLEsDAGRIAKDASGK 844
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 506-528 1.34e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 36.12  E-value: 1.34e-03
                          10        20
                  ....*....|....*....|...
gi 1062958688 506 YRCAVCGKGFCRSSTLLQHHRVH 528
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 447-529 1.45e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.24  E-value: 1.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 447 EKPFKCP--ECGKRFGQSSVLAIHART-HLPGRTYSCPDcgktfnrsstLIQHQRSHTGERPYRCAVCGKGFcRSSTLLQ 523
Cdd:COG5189   347 GKPYKCPveGCNKKYKNQNGLKYHMLHgHQNQKLHENPS----------PEKMNIFSAKDKPYRCEVCDKRY-KNLNGLK 415


                  ....*.
gi 1062958688 524 HHRVHS 529
Cdd:COG5189   416 YHRKHS 421
zf-H2C2_2 pfam13465
Zinc-finger double domain;
380-405 1.50e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 1.50e-03
                          10        20
                  ....*....|....*....|....*.
gi 1062958688 380 YLLRHQRTHSHERPYSCPECGKCYSQ 405
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
dnaA PRK14086
chromosomal replication initiator protein DnaA;
60-166 1.96e-03

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 40.96  E-value: 1.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688  60 PQSPGFGPQSPEFEPQSPRFEPespgfeSRSPGFVPPSPEFAPrspeSDSQSPDFEPQSPRYEPQSPGYEPkspgyEPRS 139
Cdd:PRK14086  130 PPGLPRQDQLPTARPAYPAYQQ------RPEPGAWPRAADDYG----WQQQRLGFPPRAPYASPASYAPEQ-----ERDR 194

                          90       100
                  ....*....|....*....|....*..
gi 1062958688 140 PGYEPKSPGYEPRSPGYESQSPRYEPQ 166
Cdd:PRK14086  195 EPYDAGRPEYDQRRRDYDHPRPDWDRP 221
PHA00733 PHA00733
hypothetical protein
 477-524 2.05e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 38.70  E-value: 2.05e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1062958688 477 TYSCPDCGKTFNRSSTLIQHQRshTGERPYRCAVCGKGFCRSSTLLQH 524
Cdd:PHA00733   73 PYVCPLCLMPFSSSVSLKQHIR--YTEHSKVCPVCGKEFRNTDSTLDH 118
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 94-251 2.07e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 41.22  E-value: 2.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688   94 VPPSPEFAprSPESDSQSPDFEPQS-PRYEPQSPGYEPKSPGYEPRSPGYEPKSPGYEPRSPGYESQSPRYEP--QSPGY 170
Cdd:PRK10263   340 VTQTPPVA--SVDVPPAQPTVAWQPvPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPaaEQPAQ 417

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688  171 EPQNPEFKTQSPEFEAESSKFQE-GAEILLNPEEKNPLSIPLGVH-PLDAFTQGFGEQPSggmPLGPPFEMPTGALLAPP 248
Cdd:PRK10263   418 QPYYAPAPEQPAQQPYYAPAPEQpVAGNAWQAEEQQSTFAPQSTYqTEQTYQQPAAQEPL---YQQPQPVEQQPVVEPEP 494


                   ...
gi 1062958688  249 QFE 251
Cdd:PRK10263   495 VVE 497
InsA COG3677
Transposase InsA [Mobilome: prophages, transposons];
339-540 2.11e-03

Transposase InsA [Mobilome: prophages, transposons];


Pssm-ID: 442893 [Multi-domain]  Cd Length: 241  Bit Score: 40.24  E-value: 2.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 339 KCPRCGkafadSSYLLRHQRTHSGQKPYKCPHCGKAF-GDSSYLLRHQRTHSHERpyscpeCGKCYSQNSSLRSHQRVht 417
Cdd:COG3677    18 VCPHCG-----STRIVKNGKTRNGRQRYRCKDCGRTFtVTTGTIFEGSKLPLWLQ------AIRLLLNGISLRQIARV-- 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 418 gqrpfsCGIcgksfSQRSAL--IPHARSHAREKPFKCPECGKRFGQSSVLAIHARTHLPGRTYSCPDCGKTFNRSSTLIQ 495
Cdd:COG3677    85 ------LGV-----SYKTVWrwLHRIREALDELVDEVDEGEGLVGEEDEKTKSKRRRKRGKKLVKGLKKGVVVKVRARGA 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1062958688 496 HQRSHTGER--PYRCAVCGKGFCRSSTLLQHHRVHSGERPYKCDDCG 540
Cdd:COG3677   154 RKSKLAVRLelADLLLRRIILAALVAPLATDLAVGVDSKKHELLELA 200
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 74-210 2.13e-03

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 40.91  E-value: 2.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688  74 PQSPRfEPESPGFESRSPGFVP-PSPEFAPRSPESDSQSPDFEPQSPRYEPQ-SPGYEPKSPGYEPrspgyEPKSPGYEP 151
Cdd:NF033839  281 QDTPK-EPGNKKPSAPKPGMQPsPQPEKKEVKPEPETPKPEVKPQLEKPKPEvKPQPEKPKPEVKP-----QLETPKPEV 354

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 152 RsPGYESQSPRYEPQSPGYEPQ-NPEFKTQSPEFEAESSKFQegAEILLNPEEKNPLSIP 210
Cdd:NF033839  355 K-PQPEKPKPEVKPQPEKPKPEvKPQPETPKPEVKPQPEKPK--PEVKPQPEKPKPEVKP 411
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 60-206 2.83e-03

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 40.52  E-value: 2.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688  60 PQSPGFGPQSPEFEPQSPRFEPE-SPGFESRSPGFVP----PSPEFAPR--------SPESDSQSPDFEPQ----SPRYE 122
Cdd:NF033839  309 EVKPEPETPKPEVKPQLEKPKPEvKPQPEKPKPEVKPqletPKPEVKPQpekpkpevKPQPEKPKPEVKPQpetpKPEVK 388

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 123 PQSPGYEPK-SPGYEPRSPGYEPKSPGYEPR-SPGYESQSPRYEPQSPGYEPQ-NPEFKTQSPEFEAESSKfqEGAEILL 199
Cdd:NF033839  389 PQPEKPKPEvKPQPEKPKPEVKPQPEKPKPEvKPQPEKPKPEVKPQPEKPKPEvKPQPEKPKPEVKPQPET--PKPEVKP 466


                  ....*..
gi 1062958688 200 NPEEKNP 206
Cdd:NF033839  467 QPEKPKP 473
zf-H2C2_2 pfam13465
Zinc-finger double domain;
440-459 2.98e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 2.98e-03
                          10        20
                  ....*....|....*....|
gi 1062958688 440 HARSHAREKPFKCPECGKRF 459
Cdd:pfam13465   5 HMRTHTGEKPYKCPECGKSF 24
ZnF_C2H2 smart00355
zinc finger;
366-388 3.09e-03

zinc finger;


Pssm-ID: 197676  Cd Length: 23  Bit Score: 35.13  E-value: 3.09e-03
                           10        20
                   ....*....|....*....|...
gi 1062958688  366 YKCPHCGKAFGDSSYLLRHQRTH 388
Cdd:smart00355   1 YRCPECGKVFKSKSALREHMRTH 23
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 450-472 3.21e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 35.35  E-value: 3.21e-03
                          10        20
                  ....*....|....*....|...
gi 1062958688 450 FKCPECGKRFGQSSVLAIHARTH 472
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 284-328 3.97e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 36.38  E-value: 3.97e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1062958688 284 CGICGKSFGRGSTLIQHQRIHTgekpYKCEVCSKAFSQSSDLIKH 328
Cdd:cd20908     4 CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 2-162 4.15e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.06  E-value: 4.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688   2 EREASPWGLE-PRDMQSPDEMGSP----EGSLKGNMSENEEEEISQQEGT-----GDYEVEEISFGLEPQSPGFG----- 66
Cdd:PTZ00449  640 QRPSSPERPEgPKIIKSPKPPKSPkppfDPKFKEKFYDDYLDAAAKSKETkttvvLDESFESILKETLPETPGTPfttpr 719

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688  67 ------PQSPEFePQSPRFEPESPGfESRSPGFVPPSPE--FAPRSPeSDSQSPDFEPQSPRYEP-QSPGYEPKSPGYEP 137
Cdd:PTZ00449  720 plppklPRDEEF-PFEPIGDPDAEQ-PDDIEFFTPPEEErtFFHETP-ADTPLPDILAEEFKEEDiHAETGEPDEAMKRP 796

                         170       180
                  ....*....|....*....|....*.
gi 1062958688 138 RSPG-YEPKSPGYEPRSPGYESQSPR 162
Cdd:PTZ00449  797 DSPSeHEDKPPGDHPSLPKKRHRLDG 822
PHA03247 PHA03247
large tegument protein UL36; Provisional
 60-183 4.44e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.31  E-value: 4.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688   60 PQSPGFGPQSPEFEPQSPRFEPESPG----FESRSPGfVPPSPEfAPRSPESDSQSPDFEPQSPRYEPQSPGYEPKSPGY 135
Cdd:PHA03247  2554 PLPPAAPPAAPDRSVPPPRPAPRPSEpavtSRARRPD-APPQSA-RPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSP 2631

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 1062958688  136 EPR--SPGYEPKSPGYEPRSPGYESQSPRYEPQSPGYEPQNPEFKTQSPE 183
Cdd:PHA03247  2632 SPAanEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQ 2681
dnaA PRK14086
chromosomal replication initiator protein DnaA;
42-186 5.22e-03

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 39.81  E-value: 5.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688  42 QQEGTGDYEVEEISFGLEPQSPGFGPQSPEFEPQSprfepESPGFESRSPGFVPPSPEFAPRSPESDSQSPDFEPQSpRY 121
Cdd:PRK14086  151 QRPEPGAWPRAADDYGWQQQRLGFPPRAPYASPAS-----YAPEQERDREPYDAGRPEYDQRRRDYDHPRPDWDRPR-RD 224

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1062958688 122 EPQSPGYEPKSpGYEPRSPGYEPKSPgyeprspgyESQSPRYEPQSPGYEPQNPEFKTQSPEFEA 186
Cdd:PRK14086  225 RTDRPEPPPGA-GHVHRGGPGPPERD---------DAPVVPIRPSAPGPLAAQPAPAPGPGEPTA 279
PHA00733 PHA00733
hypothetical protein
 349-412 5.45e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 37.16  E-value: 5.45e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1062958688 349 DSSYLLRHQRTHSgQKPYKCPHCGKAFGDSSYLLRHQRTHSHERpySCPECGKCYSQNSSLRSH 412
Cdd:PHA00733   58 ESSYLYKLLTSKA-VSPYVCPLCLMPFSSSVSLKQHIRYTEHSK--VCPVCGKEFRNTDSTLDH 118
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 59-206 5.49e-03

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 39.37  E-value: 5.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688  59 EPQSPGFGPQ-SPEFEPQSPRFEPESPGFESRsPGFVPPSPEFAPR--------SPESDSQSPDFEPQ----SPRYEPQS 125
Cdd:NF033839  291 KPSAPKPGMQpSPQPEKKEVKPEPETPKPEVK-PQLEKPKPEVKPQpekpkpevKPQLETPKPEVKPQpekpKPEVKPQP 369

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688 126 PGYEPKSPGyEPRSPGYEPKSPGYEPR---SPGYESQSPRYEPQ--------SPGYEPQNPEFKTQSPEFEAESSKFQEG 194
Cdd:NF033839  370 EKPKPEVKP-QPETPKPEVKPQPEKPKpevKPQPEKPKPEVKPQpekpkpevKPQPEKPKPEVKPQPEKPKPEVKPQPEK 448

                         170
                  ....*....|..
gi 1062958688 195 AEILLNPEEKNP 206
Cdd:NF033839  449 PKPEVKPQPETP 460
PHA00733 PHA00733
hypothetical protein
 377-440 5.72e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 37.16  E-value: 5.72e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1062958688 377 DSSYLLRHQRTHSHErPYSCPECGKCYSQNSSLRSHQRVHTGQRpfSCGICGKSFSQRSALIPH 440
Cdd:PHA00733   58 ESSYLYKLLTSKAVS-PYVCPLCLMPFSSSVSLKQHIRYTEHSK--VCPVCGKEFRNTDSTLDH 118
PHA00733 PHA00733
hypothetical protein
 337-384 6.54e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 37.16  E-value: 6.54e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1062958688 337 PYKCPRCGKAFADSSYLLRHQRTHSGQKpyKCPHCGKAFGDSSYLLRH 384
Cdd:PHA00733   73 PYVCPLCLMPFSSSVSLKQHIRYTEHSK--VCPVCGKEFRNTDSTLDH 118
ZnF_C2H2 smart00355
zinc finger;
534-556 6.72e-03

zinc finger;


Pssm-ID: 197676  Cd Length: 23  Bit Score: 34.36  E-value: 6.72e-03
                           10        20
                   ....*....|....*....|...
gi 1062958688  534 YKCDDCGKAFSQSSDLIRHQRTH 556
Cdd:smart00355   1 YRCPECGKVFKSKSALREHMRTH 23
OrfB_Zn_ribbon pfam07282
Putative transposase DNA-binding domain; This putative domain is found at the C-terminus of a ...
 452-489 7.47e-03

Putative transposase DNA-binding domain; This putative domain is found at the C-terminus of a large number of transposase proteins. This domain contains four conserved cysteines suggestive of a zinc binding domain. Given the need for transposases to bind DNA as well as the large number of DNA-binding zinc fingers we hypothesize this domain is DNA-binding.


Pssm-ID: 284650 [Multi-domain]  Cd Length: 69  Bit Score: 35.27  E-value: 7.47e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1062958688 452 CPECGKRfgqssvlaihARTHLPGRTYSCPDCGKTFNR 489
Cdd:pfam07282  31 CSVCGHK----------NKESLSGRTFVCPNCGFVADR 58
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 19-229 7.96e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 39.29  E-value: 7.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688  19 DEMGSPEGSLKGNMSENEEEEISQQEGTG-DYEVEEI-SFGLEPQSPGfGPQSPEfEPQSPRfEPESPGFESRSPGfvPP 96
Cdd:PTZ00449  536 DSKESDEPKEGGKPGETKEGEVGKKPGPAkEHKPSKIpTLSKKPEFPK-DPKHPK-DPEEPK-KPKRPRSAQRPTR--PK 610

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688  97 SPEFAPRSPESDSQSPDFEPQSPRYEPqsPGYEPKSPgYEPRSPGY--EPKSPGyEPRSPGYESQSPRYEPQSPGYEPQN 174
Cdd:PTZ00449  611 SPKLPELLDIPKSPKRPESPKSPKRPP--PPQRPSSP-ERPEGPKIikSPKPPK-SPKPPFDPKFKEKFYDDYLDAAAKS 686

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1062958688 175 PEFKTQSPEFEAESSKFQEgaeiLLNPEEKNPLSIPLGVHPLDAFTQGFGEQPSG 229
Cdd:PTZ00449  687 KETKTTVVLDESFESILKE----TLPETPGTPFTTPRPLPPKLPRDEEFPFEPIG 737
ZnF_C2H2 smart00355
zinc finger;
310-332 8.42e-03

zinc finger;


Pssm-ID: 197676  Cd Length: 23  Bit Score: 33.98  E-value: 8.42e-03
                           10        20
                   ....*....|....*....|...
gi 1062958688  310 YKCEVCSKAFSQSSDLIKHQRTH 332
Cdd:smart00355   1 YRCPECGKVFKSKSALREHMRTH 23
ZnF_C2H2 smart00355
zinc finger;
478-500 8.50e-03

zinc finger;


Pssm-ID: 197676  Cd Length: 23  Bit Score: 33.98  E-value: 8.50e-03
                           10        20
                   ....*....|....*....|...
gi 1062958688  478 YSCPDCGKTFNRSSTLIQHQRSH 500
Cdd:smart00355   1 YRCPECGKVFKSKSALREHMRTH 23
PHA03377 PHA03377
EBNA-3C; Provisional
 60-207 9.12e-03

EBNA-3C; Provisional


Pssm-ID: 177614 [Multi-domain]  Cd Length: 1000  Bit Score: 38.88  E-value: 9.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688   60 PQSPGFGPQSPEfEPQSPRfepesPGFESRSPgfvPPSPEFAPRSPE----SDSQSPDF------EPQSPRYE------P 123
Cdd:PHA03377   744 HQAPYSGHEEPQ-AQQAPY-----PGYWEPRP---PQAPYLGYQEPQaqgvQVSSYPGYagpwglRAQHPRYRhswaywS 814

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062958688  124 QSPGYEPKSPGYEPRSPGYEPKSPGYEPRSPGYESQSPRYEPQSPGYEPQnpefKTQSPEFEAESSKFQEGAEILLNPEE 203
Cdd:PHA03377   815 QYPGHGHPQGPWAPRPPHLPPQWDGSAGHGQDQVSQFPHLQSETGPPRLQ----LSQVPQLPYSQTLVSSSAPSWSSPQP 890


                   ....
gi 1062958688  204 KNPL 207
Cdd:PHA03377   891 RAPI 894
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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