|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
764-992 |
2.59e-63 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
:
Pssm-ID: 397130 Cd Length: 203 Bit Score: 214.15 E-value: 2.59e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 764 FRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlkvpttekpTVTVNFR 843
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELLKLIMSDPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNL---------RNPTDFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 844 KLLLNRCQKEFEKdkdddevfekkqkemdeaataeergrlKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCV 923
Cdd:pfam02854 72 IHLLNRLQEEFEK---------------------------RFELEENEQGNRRRRLGLVRFLGELYKFGLLTEKILFECL 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1046853695 924 VKLLKNH-------DEESLECLCRLLTTIGKDLDFAKAKPRMDQYFNQMEKII---KEKKTSSRIRFMLQDVLDLRQSN 992
Cdd:pfam02854 125 KELLSSLtkedlkrDLFNLECLLTLLTTIGKLLENEKLPKLMDQFLDEIQKYVlskDDPKLSSRLRFMLQDLIELRKNK 203
|
|
| W2_eIF4G1_like |
cd11559 |
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar ... |
1440-1569 |
1.99e-55 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; eIF4G1 is a component of the multi-subunit eukaryotic translation initiation factor 4F, which facilitates recruitment of the mRNA to the ribosome, a rate-limiting step during translation initiation. This C-terminal domain, whose structure resembles that of a set of concatenated HEAT repeats, has been associated with binding to/recruiting the kinase Mnk1, which phosphorylates eIF4E.
:
Pssm-ID: 211397 Cd Length: 134 Bit Score: 189.03 E-value: 1.99e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 1440 EELRRQLEKLLKDGGSNQRVFDWIEANLNEQQIASNTLVRALMTTVCYSAIIFETPLRVDVQVLKVRARLLQKYL-SDEQ 1518
Cdd:cd11559 4 LRVQAELLKLLQEDPNPDELYKWIKENVSPELYASPGFVRALMTAVLKYAIEEKSLPEKEKALLEKYAPLLQKYLdDDEQ 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1046853695 1519 KELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPA 1569
Cdd:cd11559 84 LQLQALYALQALVHTLEFPKGLLLRFFDALYDEDVIEEEAFLKWKEDVDPA 134
|
|
| MA3 |
pfam02847 |
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain ... |
1241-1353 |
3.32e-35 |
|
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains.
:
Pssm-ID: 397128 Cd Length: 113 Bit Score: 130.09 E-value: 3.32e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 1241 VERKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRLGIESTLERSTIAREHMGRLLHQLLCAGHLSTAQYYQGLYE 1320
Cdd:pfam02847 1 LKRKIFLILEEYLSSGDYDEAARCLLKLGLPSQHHEVVKVLIECALEESKTYREFYGLLLERLCEFNLISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1046853695 1321 TLELAEDMEIDIPHVWLYLAELITPILQEDGVP 1353
Cdd:pfam02847 81 VLEDLEDLELDIPNAWRNLAEFVARLISDDGLP 113
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
4-457 |
2.39e-09 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 62.65 E-value: 2.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 4 APQPTGPPPARSPGLPQPAFPPGQTAPVVFSTPQATQMNTPS-----------QPRQGGF-RSLQHFYPSRA---QPPSS 68
Cdd:PHA03247 2477 APVYRRPAEARFPFAAGAAPDPGGGGPPDPDAPPAPSRLAPAilpdepvgepvHPRMLTWiRGLEELASDDAgdpPPPLP 2556
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 69 AASRVQSAAPARPGPAPHVYPAGSQVMMIPSQISYSASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGA-SPTEFGT 147
Cdd:PHA03247 2557 PAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPpSPSPAAN 2636
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 148 YAGAYYPAQSVQQFPASVAPAPVLMNQPPQIapKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQtGGSLEPQPN 227
Cdd:PHA03247 2637 EPDPHPPPTVPPPERPRDDPAPGRVSRPRRA--RRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPP-PPTPEPAPH 2713
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 228 GESPqvAVIIRPDDRSQGAAIGGRPGLPGPEHSPGTESQPSSPSPTPSPPPILEPGSESNLGVLSIPGDTMTTGMIPISV 307
Cdd:PHA03247 2714 ALVS--ATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASL 2791
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 308 EESTPISCESGEPyclSPEPTLAEPILEVEVTLSKPIPESEFSSSPLQVSTSLVPHRAETHEPNG--VIPSEDL------ 379
Cdd:PHA03247 2792 SESRESLPSPWDP---ADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGgsVAPGGDVrrrpps 2868
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1046853695 380 EPEVESSTEPAPPPLSACASESLV-PIAPTAQPEELLNGAPSPPAVDlSPVSEPEEQAKEVPSAALASIVSPTPPVAPS 457
Cdd:PHA03247 2869 RSPAAKPAAPARPPVRRLARPAVSrSTESFALPPDQPERPPQPQAPP-PPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT 2946
|
|
| rad2 super family |
cl36701 |
DNA excision repair protein (rad2); All proteins in this family for which functions are known ... |
505-610 |
2.12e-03 |
|
DNA excision repair protein (rad2); All proteins in this family for which functions are known are flap endonucleases that generate the 3' incision next to DNA damage as part of nucleotide excision repair. This family is related to many other flap endonuclease families including the fen1 family. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
The actual alignment was detected with superfamily member TIGR00600:
Pssm-ID: 273166 [Multi-domain] Cd Length: 1034 Bit Score: 42.96 E-value: 2.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 505 AAPQVAVSVPKRRRKIkELNKKEAVGDllDAFKEVDPAVPEVENQPPTGSNPSPESEGSAALPQPEEAEET------WDS 578
Cdd:TIGR00600 632 SADLLLISNPMEVEPM-ESEKEESESD--GSFIEVDSVSSTLELQVPSKSQPTDESEENAENKVASIEGEHrkeiedLLF 708
|
90 100 110
....*....|....*....|....*....|..
gi 1046853695 579 KEDKIHNAENIQPGEQKYEYKSDQWKPLNLEE 610
Cdd:TIGR00600 709 DESEEDNIVGMIEEEKDADDFKNEWQDISLEE 740
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
764-992 |
2.59e-63 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
Pssm-ID: 397130 Cd Length: 203 Bit Score: 214.15 E-value: 2.59e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 764 FRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlkvpttekpTVTVNFR 843
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELLKLIMSDPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNL---------RNPTDFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 844 KLLLNRCQKEFEKdkdddevfekkqkemdeaataeergrlKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCV 923
Cdd:pfam02854 72 IHLLNRLQEEFEK---------------------------RFELEENEQGNRRRRLGLVRFLGELYKFGLLTEKILFECL 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1046853695 924 VKLLKNH-------DEESLECLCRLLTTIGKDLDFAKAKPRMDQYFNQMEKII---KEKKTSSRIRFMLQDVLDLRQSN 992
Cdd:pfam02854 125 KELLSSLtkedlkrDLFNLECLLTLLTTIGKLLENEKLPKLMDQFLDEIQKYVlskDDPKLSSRLRFMLQDLIELRKNK 203
|
|
| W2_eIF4G1_like |
cd11559 |
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar ... |
1440-1569 |
1.99e-55 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; eIF4G1 is a component of the multi-subunit eukaryotic translation initiation factor 4F, which facilitates recruitment of the mRNA to the ribosome, a rate-limiting step during translation initiation. This C-terminal domain, whose structure resembles that of a set of concatenated HEAT repeats, has been associated with binding to/recruiting the kinase Mnk1, which phosphorylates eIF4E.
Pssm-ID: 211397 Cd Length: 134 Bit Score: 189.03 E-value: 1.99e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 1440 EELRRQLEKLLKDGGSNQRVFDWIEANLNEQQIASNTLVRALMTTVCYSAIIFETPLRVDVQVLKVRARLLQKYL-SDEQ 1518
Cdd:cd11559 4 LRVQAELLKLLQEDPNPDELYKWIKENVSPELYASPGFVRALMTAVLKYAIEEKSLPEKEKALLEKYAPLLQKYLdDDEQ 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1046853695 1519 KELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPA 1569
Cdd:cd11559 84 LQLQALYALQALVHTLEFPKGLLLRFFDALYDEDVIEEEAFLKWKEDVDPA 134
|
|
| MIF4G |
smart00543 |
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The ... |
765-992 |
7.60e-53 |
|
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA. Ponting (TiBS) "Novel eIF4G domain homologues (in press)
Pssm-ID: 214713 Cd Length: 200 Bit Score: 184.10 E-value: 7.60e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 765 RRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlKVPttekptvtvNFRK 844
Cdd:smart00543 2 KKVKGLINKLSPSNFESIIKELLKLNNSDKNLRKYILELIFEKAVEEPNFIPAYARLCALLNA-KNP---------DFGS 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 845 LLLNRCQKEFEKDkdddevfekkqkemdeaataeergrlkeeLEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVV 924
Cdd:smart00543 72 LLLERLQEEFEKG-----------------------------LESEEESDKQRRLGLVRFLGELYNFQVLTSKIILELLK 122
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1046853695 925 KLLKNH-------DEESLECLCRLLTTIGKDLDFAKAKPRMDQYFNQMEKIIKEKKT---SSRIRFMLQDVLDLRQSN 992
Cdd:smart00543 123 ELLNDLtkldpprSDFSVECLLSLLPTCGKDLEREKSPKLLDEILERLQDYLLKKDKtelSSRLRFMLELLIELRKNK 200
|
|
| MA3 |
pfam02847 |
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain ... |
1241-1353 |
3.32e-35 |
|
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains.
Pssm-ID: 397128 Cd Length: 113 Bit Score: 130.09 E-value: 3.32e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 1241 VERKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRLGIESTLERSTIAREHMGRLLHQLLCAGHLSTAQYYQGLYE 1320
Cdd:pfam02847 1 LKRKIFLILEEYLSSGDYDEAARCLLKLGLPSQHHEVVKVLIECALEESKTYREFYGLLLERLCEFNLISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1046853695 1321 TLELAEDMEIDIPHVWLYLAELITPILQEDGVP 1353
Cdd:pfam02847 81 VLEDLEDLELDIPNAWRNLAEFVARLISDDGLP 113
|
|
| MA3 |
smart00544 |
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and ... |
1241-1353 |
2.92e-34 |
|
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains Ponting (TIBS) "Novel eIF4G domain homologues" in press
Pssm-ID: 214714 Cd Length: 113 Bit Score: 127.75 E-value: 2.92e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 1241 VERKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRLGIESTLERSTIAREHMGRLLHQLLCAGHLSTAQYYQGLYE 1320
Cdd:smart00544 1 LKKKIFLIIEEYLSSGDTDEAVHCLLELKLPEQHHEVVKVLLTCALEEKRTYREMYSVLLSRLCQANVISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1046853695 1321 TLELAEDMEIDIPHVWLYLAELITPILQEDGVP 1353
Cdd:smart00544 81 LLEDIEDLELDIPNAWRNLAEFVARLISDGILP 113
|
|
| eIF5C |
smart00515 |
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5; |
1509-1591 |
2.43e-27 |
|
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5;
Pssm-ID: 214705 Cd Length: 83 Bit Score: 106.60 E-value: 2.43e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 1509 LLQKYLSDEQKELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPAEqqGKGVALKSVTAFFNWL 1588
Cdd:smart00515 3 LLKFLAKDEEEQLELLYAIEEFCVELEKLGKLLPKILKSLYDADILEEEAILKWYEKAVSAE--GKKKVRKNAKPFVTWL 80
|
...
gi 1046853695 1589 REA 1591
Cdd:smart00515 81 QEA 83
|
|
| W2 |
pfam02020 |
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of ... |
1520-1596 |
3.93e-23 |
|
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of several translation initiation factors.
Pssm-ID: 460415 Cd Length: 76 Bit Score: 94.52 E-value: 3.93e-23
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1046853695 1520 ELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPAEqQGKGVALKSVTAFFNWLREAEDEES 1596
Cdd:pfam02020 1 QVDLLLALQEFCAKLEELLKLLLKILKALYDLDIVEEEAILKWWEDVSSAE-KGMKKVRKQAKPFVEWLEEAEEESD 76
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
4-457 |
2.39e-09 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 62.65 E-value: 2.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 4 APQPTGPPPARSPGLPQPAFPPGQTAPVVFSTPQATQMNTPS-----------QPRQGGF-RSLQHFYPSRA---QPPSS 68
Cdd:PHA03247 2477 APVYRRPAEARFPFAAGAAPDPGGGGPPDPDAPPAPSRLAPAilpdepvgepvHPRMLTWiRGLEELASDDAgdpPPPLP 2556
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 69 AASRVQSAAPARPGPAPHVYPAGSQVMMIPSQISYSASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGA-SPTEFGT 147
Cdd:PHA03247 2557 PAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPpSPSPAAN 2636
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 148 YAGAYYPAQSVQQFPASVAPAPVLMNQPPQIapKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQtGGSLEPQPN 227
Cdd:PHA03247 2637 EPDPHPPPTVPPPERPRDDPAPGRVSRPRRA--RRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPP-PPTPEPAPH 2713
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 228 GESPqvAVIIRPDDRSQGAAIGGRPGLPGPEHSPGTESQPSSPSPTPSPPPILEPGSESNLGVLSIPGDTMTTGMIPISV 307
Cdd:PHA03247 2714 ALVS--ATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASL 2791
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 308 EESTPISCESGEPyclSPEPTLAEPILEVEVTLSKPIPESEFSSSPLQVSTSLVPHRAETHEPNG--VIPSEDL------ 379
Cdd:PHA03247 2792 SESRESLPSPWDP---ADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGgsVAPGGDVrrrpps 2868
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1046853695 380 EPEVESSTEPAPPPLSACASESLV-PIAPTAQPEELLNGAPSPPAVDlSPVSEPEEQAKEVPSAALASIVSPTPPVAPS 457
Cdd:PHA03247 2869 RSPAAKPAAPARPPVRRLARPAVSrSTESFALPPDQPERPPQPQAPP-PPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT 2946
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
3-179 |
8.09e-05 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 47.34 E-value: 8.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 3 KAPQPTGPPPARSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQGGFRSLQHFYPSRAQPPSSAASRVQSAAPARPG 82
Cdd:pfam09770 206 QAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTILQRPQSPQPDPAQPSIQPQA 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 83 PAPHVYPAgsQVMMIPSQIsysasqgayyipgqgrstyvvpTQQYPVQPGAPGFYPGAsptefGTYAGAYYPAQSVQQFP 162
Cdd:pfam09770 286 QQFHQQPP--PVPVQPTQI----------------------LQNPNRLSAARVGYPQN-----PQPGVQPAPAHQAHRQQ 336
|
170
....*....|....*..
gi 1046853695 163 ASVAPAPVLMNQPPQIA 179
Cdd:pfam09770 337 GSFGRQAPIITHPQQLA 353
|
|
| rad2 |
TIGR00600 |
DNA excision repair protein (rad2); All proteins in this family for which functions are known ... |
505-610 |
2.12e-03 |
|
DNA excision repair protein (rad2); All proteins in this family for which functions are known are flap endonucleases that generate the 3' incision next to DNA damage as part of nucleotide excision repair. This family is related to many other flap endonuclease families including the fen1 family. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273166 [Multi-domain] Cd Length: 1034 Bit Score: 42.96 E-value: 2.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 505 AAPQVAVSVPKRRRKIkELNKKEAVGDllDAFKEVDPAVPEVENQPPTGSNPSPESEGSAALPQPEEAEET------WDS 578
Cdd:TIGR00600 632 SADLLLISNPMEVEPM-ESEKEESESD--GSFIEVDSVSSTLELQVPSKSQPTDESEENAENKVASIEGEHrkeiedLLF 708
|
90 100 110
....*....|....*....|....*....|..
gi 1046853695 579 KEDKIHNAENIQPGEQKYEYKSDQWKPLNLEE 610
Cdd:TIGR00600 709 DESEEDNIVGMIEEEKDADDFKNEWQDISLEE 740
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
764-992 |
2.59e-63 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
Pssm-ID: 397130 Cd Length: 203 Bit Score: 214.15 E-value: 2.59e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 764 FRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlkvpttekpTVTVNFR 843
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELLKLIMSDPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNL---------RNPTDFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 844 KLLLNRCQKEFEKdkdddevfekkqkemdeaataeergrlKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCV 923
Cdd:pfam02854 72 IHLLNRLQEEFEK---------------------------RFELEENEQGNRRRRLGLVRFLGELYKFGLLTEKILFECL 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1046853695 924 VKLLKNH-------DEESLECLCRLLTTIGKDLDFAKAKPRMDQYFNQMEKII---KEKKTSSRIRFMLQDVLDLRQSN 992
Cdd:pfam02854 125 KELLSSLtkedlkrDLFNLECLLTLLTTIGKLLENEKLPKLMDQFLDEIQKYVlskDDPKLSSRLRFMLQDLIELRKNK 203
|
|
| W2_eIF4G1_like |
cd11559 |
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar ... |
1440-1569 |
1.99e-55 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; eIF4G1 is a component of the multi-subunit eukaryotic translation initiation factor 4F, which facilitates recruitment of the mRNA to the ribosome, a rate-limiting step during translation initiation. This C-terminal domain, whose structure resembles that of a set of concatenated HEAT repeats, has been associated with binding to/recruiting the kinase Mnk1, which phosphorylates eIF4E.
Pssm-ID: 211397 Cd Length: 134 Bit Score: 189.03 E-value: 1.99e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 1440 EELRRQLEKLLKDGGSNQRVFDWIEANLNEQQIASNTLVRALMTTVCYSAIIFETPLRVDVQVLKVRARLLQKYL-SDEQ 1518
Cdd:cd11559 4 LRVQAELLKLLQEDPNPDELYKWIKENVSPELYASPGFVRALMTAVLKYAIEEKSLPEKEKALLEKYAPLLQKYLdDDEQ 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1046853695 1519 KELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPA 1569
Cdd:cd11559 84 LQLQALYALQALVHTLEFPKGLLLRFFDALYDEDVIEEEAFLKWKEDVDPA 134
|
|
| MIF4G |
smart00543 |
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The ... |
765-992 |
7.60e-53 |
|
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA. Ponting (TiBS) "Novel eIF4G domain homologues (in press)
Pssm-ID: 214713 Cd Length: 200 Bit Score: 184.10 E-value: 7.60e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 765 RRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlKVPttekptvtvNFRK 844
Cdd:smart00543 2 KKVKGLINKLSPSNFESIIKELLKLNNSDKNLRKYILELIFEKAVEEPNFIPAYARLCALLNA-KNP---------DFGS 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 845 LLLNRCQKEFEKDkdddevfekkqkemdeaataeergrlkeeLEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVV 924
Cdd:smart00543 72 LLLERLQEEFEKG-----------------------------LESEEESDKQRRLGLVRFLGELYNFQVLTSKIILELLK 122
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1046853695 925 KLLKNH-------DEESLECLCRLLTTIGKDLDFAKAKPRMDQYFNQMEKIIKEKKT---SSRIRFMLQDVLDLRQSN 992
Cdd:smart00543 123 ELLNDLtkldpprSDFSVECLLSLLPTCGKDLEREKSPKLLDEILERLQDYLLKKDKtelSSRLRFMLELLIELRKNK 200
|
|
| MA3 |
pfam02847 |
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain ... |
1241-1353 |
3.32e-35 |
|
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains.
Pssm-ID: 397128 Cd Length: 113 Bit Score: 130.09 E-value: 3.32e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 1241 VERKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRLGIESTLERSTIAREHMGRLLHQLLCAGHLSTAQYYQGLYE 1320
Cdd:pfam02847 1 LKRKIFLILEEYLSSGDYDEAARCLLKLGLPSQHHEVVKVLIECALEESKTYREFYGLLLERLCEFNLISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1046853695 1321 TLELAEDMEIDIPHVWLYLAELITPILQEDGVP 1353
Cdd:pfam02847 81 VLEDLEDLELDIPNAWRNLAEFVARLISDDGLP 113
|
|
| MA3 |
smart00544 |
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and ... |
1241-1353 |
2.92e-34 |
|
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains Ponting (TIBS) "Novel eIF4G domain homologues" in press
Pssm-ID: 214714 Cd Length: 113 Bit Score: 127.75 E-value: 2.92e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 1241 VERKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRLGIESTLERSTIAREHMGRLLHQLLCAGHLSTAQYYQGLYE 1320
Cdd:smart00544 1 LKKKIFLIIEEYLSSGDTDEAVHCLLELKLPEQHHEVVKVLLTCALEEKRTYREMYSVLLSRLCQANVISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1046853695 1321 TLELAEDMEIDIPHVWLYLAELITPILQEDGVP 1353
Cdd:smart00544 81 LLEDIEDLELDIPNAWRNLAEFVARLISDGILP 113
|
|
| eIF5C |
smart00515 |
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5; |
1509-1591 |
2.43e-27 |
|
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5;
Pssm-ID: 214705 Cd Length: 83 Bit Score: 106.60 E-value: 2.43e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 1509 LLQKYLSDEQKELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPAEqqGKGVALKSVTAFFNWL 1588
Cdd:smart00515 3 LLKFLAKDEEEQLELLYAIEEFCVELEKLGKLLPKILKSLYDADILEEEAILKWYEKAVSAE--GKKKVRKNAKPFVTWL 80
|
...
gi 1046853695 1589 REA 1591
Cdd:smart00515 81 QEA 83
|
|
| W2 |
pfam02020 |
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of ... |
1520-1596 |
3.93e-23 |
|
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of several translation initiation factors.
Pssm-ID: 460415 Cd Length: 76 Bit Score: 94.52 E-value: 3.93e-23
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1046853695 1520 ELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPAEqQGKGVALKSVTAFFNWLREAEDEES 1596
Cdd:pfam02020 1 QVDLLLALQEFCAKLEELLKLLLKILKALYDLDIVEEEAILKWWEDVSSAE-KGMKKVRKQAKPFVEWLEEAEEESD 76
|
|
| W2 |
cd11473 |
C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon; This domain is found at the C-terminus of ... |
1440-1563 |
1.15e-19 |
|
C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon; This domain is found at the C-terminus of several translation initiation factors, including the epsilon chain of eIF2b, where it has been found to catalyze the conversion of eIF2.GDP to its active eIF2.GTP form. The structure of the domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211395 Cd Length: 135 Bit Score: 86.76 E-value: 1.15e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 1440 EELRRQLEKLLK-DGGSNQRVFDWIEANLNEQQIASNTLVRALMTTVCYSAIIFE----TPLRVDVQVLKVRARLLQKYL 1514
Cdd:cd11473 4 KKLRDSLLKELEeDKSSDVESVKAAKSKLDLDPISLEEVVKVLLTAVVNAVESADsislTQKEQLVLVLKKYGPVLRELL 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1046853695 1515 SD-EQKELQALYALQALVVT--LEQPANLLRMFFDALYDEDVVKEDAFYSWE 1563
Cdd:cd11473 84 KLiKKDQLYLLLKIEKLCLQlkLSELISLLEKILDLLYDADVLSEEAILSWF 135
|
|
| W2_eIF2B_epsilon |
cd11558 |
C-terminal W2 domain of eukaryotic translation initiation factor 2B epsilon; eIF2B is a ... |
1509-1596 |
9.24e-14 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 2B epsilon; eIF2B is a heteropentameric complex which functions as a guanine nucleotide exchange factor in the recycling of eIF-2 during the initiation of translation in eukaryotes. The epsilon and gamma subunits are sequence similar and both are essential in yeast. Epsilon appears to be the catalytically active subunit, with gamma enhancing its activity. The C-terminal domain of the eIF2B epsilon subunit contains bipartite motifs rich in acidic and aromatic residues, which are responsible for the interaction with eIF2. The structure of the domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211396 Cd Length: 169 Bit Score: 70.75 E-value: 9.24e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 1509 LLQKYLSDEQKELQALYALQALVVTLEQPANLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFNWL 1588
Cdd:cd11558 82 LLENYVKSQDDQVELLLALEEFCLESEEGGPLFAKLLHALYDLDILEEEAILEWWEEPDAGADEEMKKVRELVKKFIEWL 161
|
....*...
gi 1046853695 1589 REAEDEES 1596
Cdd:cd11558 162 EEAEEESD 169
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
4-457 |
2.39e-09 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 62.65 E-value: 2.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 4 APQPTGPPPARSPGLPQPAFPPGQTAPVVFSTPQATQMNTPS-----------QPRQGGF-RSLQHFYPSRA---QPPSS 68
Cdd:PHA03247 2477 APVYRRPAEARFPFAAGAAPDPGGGGPPDPDAPPAPSRLAPAilpdepvgepvHPRMLTWiRGLEELASDDAgdpPPPLP 2556
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 69 AASRVQSAAPARPGPAPHVYPAGSQVMMIPSQISYSASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGA-SPTEFGT 147
Cdd:PHA03247 2557 PAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPpSPSPAAN 2636
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 148 YAGAYYPAQSVQQFPASVAPAPVLMNQPPQIapKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQtGGSLEPQPN 227
Cdd:PHA03247 2637 EPDPHPPPTVPPPERPRDDPAPGRVSRPRRA--RRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPP-PPTPEPAPH 2713
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 228 GESPqvAVIIRPDDRSQGAAIGGRPGLPGPEHSPGTESQPSSPSPTPSPPPILEPGSESNLGVLSIPGDTMTTGMIPISV 307
Cdd:PHA03247 2714 ALVS--ATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASL 2791
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 308 EESTPISCESGEPyclSPEPTLAEPILEVEVTLSKPIPESEFSSSPLQVSTSLVPHRAETHEPNG--VIPSEDL------ 379
Cdd:PHA03247 2792 SESRESLPSPWDP---ADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGgsVAPGGDVrrrpps 2868
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1046853695 380 EPEVESSTEPAPPPLSACASESLV-PIAPTAQPEELLNGAPSPPAVDlSPVSEPEEQAKEVPSAALASIVSPTPPVAPS 457
Cdd:PHA03247 2869 RSPAAKPAAPARPPVRRLARPAVSrSTESFALPPDQPERPPQPQAPP-PPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT 2946
|
|
| W2_eIF5 |
cd11561 |
C-terminal W2 domain of eukaryotic translation initiation factor 5; eIF5 functions as a GTPase ... |
1438-1596 |
1.65e-08 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 5; eIF5 functions as a GTPase acceleration protein (GAP), as well as a GDP dissociation inhibitor (GDI) during translational initiation in eukaryotes. The structure of this C-terminal domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211399 Cd Length: 157 Bit Score: 55.31 E-value: 1.65e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 1438 AFEELRRQLEKLLKDGGSNQrvfdwIEANLNEQQIASNTLVRALmttvcysAIIFETPLRVD-VQVLKVRARLLQKYLSD 1516
Cdd:cd11561 7 RVDELGEFLKKNKDESGLSE-----LKEILKEAERLDVVKDKAV-------LVLAEVLFDENiVKEIKKRKALLLKLVTD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 1517 EQKELQALYALQALVVtlEQPANLLRMF---FDALYDEDVVKEDAFYSW---ESSKDPAEQQGKGVaLKSVTAFFNWLRE 1590
Cdd:cd11561 75 EKAQKALLGGIERFCG--KHSPELLKKVpliLKALYDNDILEEEVILKWyekVSKKYVSKEKSKKV-RKAAEPFVEWLEE 151
|
....*.
gi 1046853695 1591 AEDEES 1596
Cdd:cd11561 152 AEEEEE 157
|
|
| W2_eIF5C_like |
cd11560 |
C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins; ... |
1434-1594 |
9.73e-08 |
|
C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins; eIF5C appears to be essential for the initiation of protein translation; its actual function, and specifically that of the C-terminal W2 domain, are not well understood. The Drosophila ortholog, kra (krasavietz) or exba (extra bases), may be involved in translational inhibition in neural development. The structure of this C-terminal domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211398 [Multi-domain] Cd Length: 194 Bit Score: 54.14 E-value: 9.73e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 1434 QRALAFEELRRQLEKLLKDGGSNQRVFDWIEANLNEQQIASN--------TLVRALMTTVCYSA---IIFETPLRVdvqv 1502
Cdd:cd11560 29 YRKQASQEIKKELQQELKEMIAEEEPVKEIIAAVKEQMKKSSlpehevvgLLWTALMDAVEWSKkedQIAEQALRH---- 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 1503 LKVRARLLQKYLSDEQKELQALYALQalVVTLEQpANLLRMFFD---ALYDEDVVKEDAFYSWesSKDPAEQQGKGVALK 1579
Cdd:cd11560 105 LKKYAPLLAAFCTTARAELALLNKIQ--EYCYEN-MKFMKVFQKivkLLYKADVLSEDAILKW--YKKGHSPKGKQVFLK 179
|
170
....*....|....*
gi 1046853695 1580 SVTAFFNWLREAEDE 1594
Cdd:cd11560 180 QMEPFVEWLQEAEEE 194
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
5-360 |
3.22e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 55.71 E-value: 3.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 5 PQPTGPPPARSPGLPQP--------AFPPGQTAPVVFSTPQATQmnTPSQPRQGGFRslqhfyPSRAQPPSSAASRVQSA 76
Cdd:PHA03247 2706 PTPEPAPHALVSATPLPpgpaaarqASPALPAAPAPPAVPAGPA--TPGGPARPARP------PTTAGPPAPAPPAAPAA 2777
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 77 APARPGPAPHVYPAGSQVMMIPSQISYSASQGAYYIPGQGRSTYVVPTQQYP----VQPGAPGFYPGASPTEFgTYAGAY 152
Cdd:PHA03247 2778 GPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPpptsAQPTAPPPPPGPPPPSL-PLGGSV 2856
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 153 YPAQSVQQFPASVAPAPVL----------MNQP-------PQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTP 215
Cdd:PHA03247 2857 APGGDVRRRPPSRSPAAKPaaparppvrrLARPavsrsteSFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPP 2936
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 216 PQTGGSLEPQPNGESPQVAVIIRPDDRSqGAAIGGR------------PGLPGPEHSPGTESQPSSPSPTPSPPPIL--- 280
Cdd:PHA03247 2937 PRPQPPLAPTTDPAGAGEPSGAVPQPWL-GALVPGRvavprfrvpqpaPSREAPASSTPPLTGHSLSRVSSWASSLAlhe 3015
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 281 --EPGSESNLGVLSIPGDTMTTGMIPISVEESTPISCESGEPycLSPEPTLA---EPILEVEVTLSKPIPESEFSSSPLQ 355
Cdd:PHA03247 3016 etDPPPVSLKQTLWPPDDTEDSDADSLFDSDSERSDLEALDP--LPPEPHDPfahEPDPATPEAGARESPSSQFGPPPLS 3093
|
....*
gi 1046853695 356 VSTSL 360
Cdd:PHA03247 3094 ANAAL 3098
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
3-179 |
8.09e-05 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 47.34 E-value: 8.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 3 KAPQPTGPPPARSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQGGFRSLQHFYPSRAQPPSSAASRVQSAAPARPG 82
Cdd:pfam09770 206 QAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTILQRPQSPQPDPAQPSIQPQA 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 83 PAPHVYPAgsQVMMIPSQIsysasqgayyipgqgrstyvvpTQQYPVQPGAPGFYPGAsptefGTYAGAYYPAQSVQQFP 162
Cdd:pfam09770 286 QQFHQQPP--PVPVQPTQI----------------------LQNPNRLSAARVGYPQN-----PQPGVQPAPAHQAHRQQ 336
|
170
....*....|....*..
gi 1046853695 163 ASVAPAPVLMNQPPQIA 179
Cdd:pfam09770 337 GSFGRQAPIITHPQQLA 353
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
162-460 |
1.17e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 47.24 E-value: 1.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 162 PASVAPAPVLMNQPPQIAPK--------RERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGgSLEPQPNGESPqv 233
Cdd:PHA03247 2557 PAAPPAAPDRSVPPPRPAPRpsepavtsRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTH-APDPPPPSPSP-- 2633
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 234 aviirpddRSQGAAIGGRPGLPGPEHSPGTESQPSSPSPTPSPPPILEPGSESNLGVLSIPGDTMTTGMIPISVEESTPi 313
Cdd:PHA03247 2634 --------AANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPP- 2704
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 314 scesgEPyclSPEPTlaePILEVEVTLSKPIPESEFSSSPLQVSTSLVPHRAETHEPNGVIPSEDLEPEVESSTEPAPPP 393
Cdd:PHA03247 2705 -----PP---TPEPA---PHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA 2773
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 394 LSACASESLVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVPSAALASIVSPTP---PVAPSDTS 460
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTsaqPTAPPPPP 2843
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
327-458 |
2.06e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 42.77 E-value: 2.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 327 PTLAEPILEVEVTLSKPIPESEFSSSPLQV-STSLVPHRAETHEP------NGVIPSEDLEPEVESSTEPAPPPLSA--C 397
Cdd:PRK08691 380 PSAQTAEKETAAKKPQPRPEAETAQTPVQTaSAAAMPSEGKTAGPvsnqenNDVPPWEDAPDEAQTAAGTAQTSAKSiqT 459
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1046853695 398 ASESLVP--------IAPTAQPEELLNGAPSPPAVDLSPVSEP---EEQAKEVPSAALASIVSPTPPVAPSD 458
Cdd:PRK08691 460 ASEAETPpenqvsknKAADNETDAPLSEVPSENPIQATPNDEAvetETFAHEAPAEPFYGYGFPDNDCPPED 531
|
|
| rad2 |
TIGR00600 |
DNA excision repair protein (rad2); All proteins in this family for which functions are known ... |
505-610 |
2.12e-03 |
|
DNA excision repair protein (rad2); All proteins in this family for which functions are known are flap endonucleases that generate the 3' incision next to DNA damage as part of nucleotide excision repair. This family is related to many other flap endonuclease families including the fen1 family. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273166 [Multi-domain] Cd Length: 1034 Bit Score: 42.96 E-value: 2.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 505 AAPQVAVSVPKRRRKIkELNKKEAVGDllDAFKEVDPAVPEVENQPPTGSNPSPESEGSAALPQPEEAEET------WDS 578
Cdd:TIGR00600 632 SADLLLISNPMEVEPM-ESEKEESESD--GSFIEVDSVSSTLELQVPSKSQPTDESEENAENKVASIEGEHrkeiedLLF 708
|
90 100 110
....*....|....*....|....*....|..
gi 1046853695 579 KEDKIHNAENIQPGEQKYEYKSDQWKPLNLEE 610
Cdd:TIGR00600 709 DESEEDNIVGMIEEEKDADDFKNEWQDISLEE 740
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
4-208 |
3.43e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 42.28 E-value: 3.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 4 APQPTGPPPARSPGLPQPAFPPGQ----------TAPVVFSTPQATQMNTPSQPRQGGFRSLQHFYPSRAQPPSSAASRV 73
Cdd:PRK07764 612 AARPAAPAAPAAPAAPAPAGAAAApaeasaapapGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPA 691
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 74 QSAAPARPGPAPHVyPAGSQVMMIPSQISYSASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGayy 153
Cdd:PRK07764 692 APAGAAPAQPAPAP-AATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPA--- 767
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1046853695 154 PAQSVQQFPASVAPAPVLMNQPPQIAPKRERktiriRDPNQGGKDITEEIMsGAR 208
Cdd:PRK07764 768 AAPAAAPPPSPPSEEEEMAEDDAPSMDDEDR-----RDAEEVAMELLEEEL-GAK 816
|
|
| Rib_recp_KP_reg |
pfam05104 |
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards ... |
368-456 |
5.64e-03 |
|
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear.
Pssm-ID: 461548 [Multi-domain] Cd Length: 140 Bit Score: 38.95 E-value: 5.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 368 HEPNGVIPseDLEPEVESSTEPAPPPLSACASESLVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVPSAALASI 447
Cdd:pfam05104 44 EKPNGKLP--ESEQADESEEEPREFKTPDEAPSAALEPEPVPTPVPAPVEPEPAPPSESPAPSPKEKKKKEKKSAKVEPA 121
|
....*....
gi 1046853695 448 VSPTPPVAP 456
Cdd:pfam05104 122 ETPEAVQPK 130
|
|
| PRK11633 |
PRK11633 |
cell division protein DedD; Provisional |
346-459 |
9.24e-03 |
|
cell division protein DedD; Provisional
Pssm-ID: 236940 [Multi-domain] Cd Length: 226 Bit Score: 39.60 E-value: 9.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046853695 346 ESEFSSSPLqvstslVPHRAETHEPNGV---------IPSEDLEPEVESSTEPAPPPLSACASESLVPIAPTAQPEElln 416
Cdd:PRK11633 35 QDEFAAIPL------VPKPGDRDEPDMMpaatqalptQPPEGAAEAVRAGDAAAPSLDPATVAPPNTPVEPEPAPVE--- 105
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1046853695 417 gAPSPPavdlsPVSEPEEQAKEVPSAALASIVSPTP-PVAPSDT 459
Cdd:PRK11633 106 -PPKPK-----PVEKPKPKPKPQQKVEAPPAPKPEPkPVVEEKA 143
|
|
| |
