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Conserved domains on  [gi|1039770159|ref|XP_017176077|]
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A-kinase anchor protein 9 isoform X10 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 3534-3615 4.34e-21

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


:

Pssm-ID: 463115  Cd Length: 77  Bit Score: 89.57  E-value: 4.34e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3534 KYLRASSFRKALIYQKKYLLLLLGGFQECEDVTLGVLARMGGHLALKDSKtitnhPKAFSRFRSAVRVSIAISRMKFLVR 3613
Cdd:pfam10495    1 KLLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDDRPS-----RKPRRKLKSAALAVIAIARMKRLAR 75


                   ..
gi 1039770159 3614 RW 3615
Cdd:pfam10495   76 EW 77
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 156-964 5.65e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.96  E-value: 5.65e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  156 DIEELTQELEEMRASFgTEGLKQLQEFEAAIKQRDGIITQLTANLQQARREKDDTMVEFLELTEQSQKLQIQFQHLQANE 235
Cdd:TIGR02168  233 RLEELREELEELQEEL-KEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  236 TLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEMEKdrkiENLNAKeIQEKQALIDELNT 315
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL----EELESR-LEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  316 RVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQNE--RKCSEEIKELMRTVEELQKRNLKDSWL 393
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKElqAELEELEEELEELQEELERLEEALEEL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  394 ETS--AVRRVEQETQRKLSHLQAELDEM-----------YGKQIVQMKQELINQHMSQIEEL---KSQHKREMENTLKSD 457
Cdd:TIGR02168  467 REEleEAEQALDAAERELAQLQARLDSLerlqenlegfsEGVKALLKNQSGLSGILGVLSELisvDEGYEAAIEAALGGR 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  458 TNAAISK------------EQVNLMNAAINELNV-RLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQ 524
Cdd:TIGR02168  547 LQAVVVEnlnaakkaiaflKQNELGRVTFLPLDSiKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVL 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  525 KArQTIAEQENRLSEARKSLSTVEdLKAEIVAASESRKELELKHEAEITNYKIKLEMLEKEKNAVLDRMAEsQEAELERL 604
Cdd:TIGR02168  627 VV-DDLDNALELAKKLRPGYRIVT-LDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAE-LEKALAEL 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  605 RTQLlfsheEELSKLKEDLEVEhrinieklkdnlgihyKQQIDGLQNEMNRKMESMQCETDNLITQQNQLILENSKLRDl 684
Cdd:TIGR02168  704 RKEL-----EELEEELEQLRKE----------------LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA- 761

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  685 qeclvnskseemnlQINELQKEIEILKQEEKEkgtLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAenniLKEEKR 764
Cdd:TIGR02168  762 --------------EIEELEERLEEAEEELAE---AEAEIEELEAQIEQLKEELKALREALDELRAELTL----LNEEAA 820

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  765 VLEDKLkmyspsEQEERSIAvdpstsksadsRWQKEVAMLRKETEDLQQQCLYLNEEIEKQRNTFAFAEKNFEVNYQELQ 844
Cdd:TIGR02168  821 NLRERL------ESLERRIA-----------ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  845 REYTCLLKIRDDLEATQTKQAlEYESKLRALEEELLSKRGNPAAPKGKSSGIfpseTLEIGEVVEKdtteLMEKLEVTKR 924
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELR-ELESKRSELRRELEELREKLAQLELRLEGL----EVRIDNLQER----LSEEYSLTLE 954

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 1039770159  925 EKLELSEKVSGLSEQLKQthctinslsaEVRALKQEKEQL 964
Cdd:TIGR02168  955 EAEALENKIEDDEEEARR----------RLKRLENKIKEL 984
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1798-2460 4.14e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 4.14e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1798 ENEELMLNISSRLQAAVEKLLE---AISETNTQLEHAKVTQTELMRESFR---QKQEATESLHCLEELRERLQEES---- 1867
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEElrlEVSELEEEIEELQKELYALANEISRleqQKQILRERLANLERQLEELEAQLeele 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1868 RAREQLAEELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEA 1947
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARL 409

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1948 GPVE---QQFLQETEKLMKEKLEVQcqAEKVRGDLQKQVKALEiDVEEQVSRFIELEQEKNAELTDLRQQSQALEKQLEK 2024
Cdd:TIGR02168  410 ERLEdrrERLQQEIEELLKKLEEAE--LKELQAELEELEEELE-ELQEELERLEEALEELREELEEAEQALDAAERELAQ 486

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2025 MRKFLDEQAIDREHERDVFQQEIQKLEHQLKAVPRIQPVSEH-------------------QAREVEQLT------NHLK 2079
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyeaaieaalggrlQAVVVENLNaakkaiAFLK 566

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2080 EKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQALLASAEPFPKV------------------EDQKRSGA--- 2138
Cdd:TIGR02168  567 QNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvvddldnalELAKKLRPgyr 646

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2139 -VEADPELSLEVQLQVERDATDR-----KQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENR 2212
Cdd:TIGR02168  647 iVTLDGDLVRPGGVITGGSAKTNssileRRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSR 726

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2213 LfkvIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQREGARTLPEDEESFKHQLDKVTA 2292
Cdd:TIGR02168  727 Q---ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2293 EKLVLEQQVETTNQVMTHMNNVLKEINFKMDQITQSLCNLNKECASNEelpslpkESVHMTVHELGSDNLQPEDAPAQ-- 2370
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS-------EDIESLAAEIEELEELIEELESEle 876

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2371 DVTKPLEKQTSLTRLQKSPEASRTQEIESLASSVGAKDVELTQCREQTETIQ---EQAQSETDRLQKKLTDLQRSLEKFA 2447
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLElrlEGLEVRIDNLQERLSEEYSLTLEEA 956

                          730
                   ....*....|...
gi 1039770159 2448 AALVSQVQMEAAQ 2460
Cdd:TIGR02168  957 EALENKIEDDEEE 969
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2966-3301 1.73e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.73e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2966 EMQLELSSLRDRAAELQEQLSS--------EKmvVAELKSELAQAKLELG-----------TTLKAQHKRLK-ELEAFRS 3025
Cdd:COG1196    183 ATEENLERLEDILGELERQLEPlerqaekaER--YRELKEELKELEAELLllklreleaelEELEAELEELEaELEELEA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3026 EVKEKTDEIHFLSDTLAREQKNSLELQWALEKEKARSGHHEGREKEELEDLKFSLEDQKRRNTQLNLLLEQQKQLLNESQ 3105
Cdd:COG1196    261 ELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELE 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3106 QKIESQKMLHDAQLSEEQGRNLGLQALLESEQVRIQEMKSTLDKERELYAQLQSREDggqpppalpsedlLKELQKQLEE 3185
Cdd:COG1196    341 ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE-------------LAAQLEELEE 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3186 KHSRIVELLSETEKYKLDSLQTRQQMEKDRQVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQQVYKLDLEGK 3265
Cdd:COG1196    408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELA 487

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 1039770159 3266 RLQGLMQEFQKQELEPEEKPGSRGLVDQNLNEPATW 3301
Cdd:COG1196    488 EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523
DUF5401 super family cl38662
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1523-1708 4.33e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


The actual alignment was detected with superfamily member pfam17380:

Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.19  E-value: 4.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1523 VRKSMHDEVLVSSMDTSRQLILNEQLEDMRQELVRQYEEHQQATEMLRQAHMQQMERQREDQEQLQEEIKRLNEQLA--- 1599
Cdd:pfam17380  394 VRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEerk 473

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1600 ------QKSSIDTEHVVSERERVLLEELEALKQLPLA---GRKELCCELRHSSTQTQDGHDDQEVEEQTLKDKTLERSPE 1670
Cdd:pfam17380  474 rkklelEKEKRDRKRAEEQRRKILEKELEERKQAMIEeerKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRR 553

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1039770159 1671 DALLDRNLSNERYALkKANNRLLKILLEVVKTTSAAEE 1708
Cdd:pfam17380  554 IQEQMRKATEERSRL-EAMEREREMMRQIVESEKARAE 590
 
Name Accession Description Interval E-value
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 3534-3615 4.34e-21

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


Pssm-ID: 463115  Cd Length: 77  Bit Score: 89.57  E-value: 4.34e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3534 KYLRASSFRKALIYQKKYLLLLLGGFQECEDVTLGVLARMGGHLALKDSKtitnhPKAFSRFRSAVRVSIAISRMKFLVR 3613
Cdd:pfam10495    1 KLLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDDRPS-----RKPRRKLKSAALAVIAIARMKRLAR 75


                   ..
gi 1039770159 3614 RW 3615
Cdd:pfam10495   76 EW 77
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 156-964 5.65e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.96  E-value: 5.65e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  156 DIEELTQELEEMRASFgTEGLKQLQEFEAAIKQRDGIITQLTANLQQARREKDDTMVEFLELTEQSQKLQIQFQHLQANE 235
Cdd:TIGR02168  233 RLEELREELEELQEEL-KEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  236 TLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEMEKdrkiENLNAKeIQEKQALIDELNT 315
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL----EELESR-LEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  316 RVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQNE--RKCSEEIKELMRTVEELQKRNLKDSWL 393
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKElqAELEELEEELEELQEELERLEEALEEL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  394 ETS--AVRRVEQETQRKLSHLQAELDEM-----------YGKQIVQMKQELINQHMSQIEEL---KSQHKREMENTLKSD 457
Cdd:TIGR02168  467 REEleEAEQALDAAERELAQLQARLDSLerlqenlegfsEGVKALLKNQSGLSGILGVLSELisvDEGYEAAIEAALGGR 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  458 TNAAISK------------EQVNLMNAAINELNV-RLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQ 524
Cdd:TIGR02168  547 LQAVVVEnlnaakkaiaflKQNELGRVTFLPLDSiKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVL 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  525 KArQTIAEQENRLSEARKSLSTVEdLKAEIVAASESRKELELKHEAEITNYKIKLEMLEKEKNAVLDRMAEsQEAELERL 604
Cdd:TIGR02168  627 VV-DDLDNALELAKKLRPGYRIVT-LDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAE-LEKALAEL 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  605 RTQLlfsheEELSKLKEDLEVEhrinieklkdnlgihyKQQIDGLQNEMNRKMESMQCETDNLITQQNQLILENSKLRDl 684
Cdd:TIGR02168  704 RKEL-----EELEEELEQLRKE----------------LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA- 761

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  685 qeclvnskseemnlQINELQKEIEILKQEEKEkgtLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAenniLKEEKR 764
Cdd:TIGR02168  762 --------------EIEELEERLEEAEEELAE---AEAEIEELEAQIEQLKEELKALREALDELRAELTL----LNEEAA 820

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  765 VLEDKLkmyspsEQEERSIAvdpstsksadsRWQKEVAMLRKETEDLQQQCLYLNEEIEKQRNTFAFAEKNFEVNYQELQ 844
Cdd:TIGR02168  821 NLRERL------ESLERRIA-----------ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  845 REYTCLLKIRDDLEATQTKQAlEYESKLRALEEELLSKRGNPAAPKGKSSGIfpseTLEIGEVVEKdtteLMEKLEVTKR 924
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELR-ELESKRSELRRELEELREKLAQLELRLEGL----EVRIDNLQER----LSEEYSLTLE 954

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 1039770159  925 EKLELSEKVSGLSEQLKQthctinslsaEVRALKQEKEQL 964
Cdd:TIGR02168  955 EAEALENKIEDDEEEARR----------RLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1798-2460 4.14e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 4.14e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1798 ENEELMLNISSRLQAAVEKLLE---AISETNTQLEHAKVTQTELMRESFR---QKQEATESLHCLEELRERLQEES---- 1867
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEElrlEVSELEEEIEELQKELYALANEISRleqQKQILRERLANLERQLEELEAQLeele 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1868 RAREQLAEELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEA 1947
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARL 409

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1948 GPVE---QQFLQETEKLMKEKLEVQcqAEKVRGDLQKQVKALEiDVEEQVSRFIELEQEKNAELTDLRQQSQALEKQLEK 2024
Cdd:TIGR02168  410 ERLEdrrERLQQEIEELLKKLEEAE--LKELQAELEELEEELE-ELQEELERLEEALEELREELEEAEQALDAAERELAQ 486

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2025 MRKFLDEQAIDREHERDVFQQEIQKLEHQLKAVPRIQPVSEH-------------------QAREVEQLT------NHLK 2079
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyeaaieaalggrlQAVVVENLNaakkaiAFLK 566

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2080 EKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQALLASAEPFPKV------------------EDQKRSGA--- 2138
Cdd:TIGR02168  567 QNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvvddldnalELAKKLRPgyr 646

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2139 -VEADPELSLEVQLQVERDATDR-----KQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENR 2212
Cdd:TIGR02168  647 iVTLDGDLVRPGGVITGGSAKTNssileRRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSR 726

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2213 LfkvIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQREGARTLPEDEESFKHQLDKVTA 2292
Cdd:TIGR02168  727 Q---ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2293 EKLVLEQQVETTNQVMTHMNNVLKEINFKMDQITQSLCNLNKECASNEelpslpkESVHMTVHELGSDNLQPEDAPAQ-- 2370
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS-------EDIESLAAEIEELEELIEELESEle 876

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2371 DVTKPLEKQTSLTRLQKSPEASRTQEIESLASSVGAKDVELTQCREQTETIQ---EQAQSETDRLQKKLTDLQRSLEKFA 2447
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLElrlEGLEVRIDNLQERLSEEYSLTLEEA 956

                          730
                   ....*....|...
gi 1039770159 2448 AALVSQVQMEAAQ 2460
Cdd:TIGR02168  957 EALENKIEDDEEE 969
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 146-747 3.85e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.60  E-value: 3.85e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  146 VEKELAEKQHDIEELTQELEEMRAsfgteglkQLQEFEAAIKQRDGIITQLTANLQQARRekddtmvEFLELTEQSQKLQ 225
Cdd:COG1196    237 LEAELEELEAELEELEAELEELEA--------ELAELEAELEELRLELEELELELEEAQA-------EEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  226 IQFQHLQANETLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEMEKDRKIEnlnakEIQE 305
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA-----ELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  306 KQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEIKELMRTVEELQK 385
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  386 RNLKDSwLETSAVRRVEQETQRKLSHLQAELDEMygKQIVQMKQELINQHMSQIEELKSQHKREMENTLKSDTNAAISKE 465
Cdd:COG1196    457 EEEALL-ELLAELLEEAALLEAALAELLEELAEA--AARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  466 QV------NLMNAAINELNVRLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKARQTIAEQENRLSE 539
Cdd:COG1196    534 AAyeaaleAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  540 ARKSLSTVEDLKAEIVAASESRKELELKHEAEITnyKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKL 619
Cdd:COG1196    614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR--EVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  620 KEDLEVEHRINIEKLKDnlgihyKQQIDGLQNEMNRKMESMQCETDNLITQQNQLILENSKLRDLQEclvnSKSEEMNLQ 699
Cdd:COG1196    692 ELELEEALLAEEEEERE------LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA----LEELPEPPD 761

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1039770159  700 INELQKEIEILKQEEKEKGTL----EQEVQELQlktEQLEKqLKEKEDDLQE 747
Cdd:COG1196    762 LEELERELERLEREIEALGPVnllaIEEYEELE---ERYDF-LSEQREDLEE 809
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1809-2293 6.24e-13

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 75.46  E-value: 6.24e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1809 RLQAAVEKLLEAISETNTQLEHAKVTQTEL--MRESFRQKQEATESLhcleelrerlqeesrareqlAEELNKAESVIDG 1886
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEAdeVLEEHEERREELETL--------------------EAEIEDLRETIAE 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1887 YSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMR---AEAGPVEQQFLQETEKLMK 1963
Cdd:PRK02224   270 TEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRdrlEECRVAAQAHNEEAESLRE 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1964 EKLEVQCQAEKVR---GDLQKQVKALEIDVEEQVSRFIELEqeknAELTDLRQQSQALEKQLEKMRKFLDEqaidREHER 2040
Cdd:PRK02224   350 DADDLEERAEELReeaAELESELEEAREAVEDRREEIEELE----EEIEELRERFGDAPVDLGNAEDFLEE----LREER 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2041 DVFQQEIQKLEHQLKAVpriqpvsEHQAREVEQLTNHLK-----------EKTDRCSELLLSKEQLQRDIQERNEEIEKL 2109
Cdd:PRK02224   422 DELREREAELEATLRTA-------RERVEEAEALLEAGKcpecgqpvegsPHVETIEEDRERVEELEAELEDLEEEVEEV 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2110 ECRVRELEQALLASAEPFPKVEDQKRSGAVEADPELSLEVQlqveRDATDRKQKEITNLEEQLEQFRE---ELENKNDEV 2186
Cdd:PRK02224   495 EERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEK----RERAEELRERAAELEAEAEEKREaaaEAEEEAEEA 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2187 QELLMQLEIQRKESTTRLQELQQenrlfkvIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEVVST 2266
Cdd:PRK02224   571 REEVAELNSKLAELKERIESLER-------IRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEF 643

                          490       500
                   ....*....|....*....|....*...
gi 1039770159 2267 EQQR-EGARtlpEDEESFKHQLDKVTAE 2293
Cdd:PRK02224   644 DEARiEEAR---EDKERAEEYLEQVEEK 668
PTZ00121 PTZ00121
MAEBL; Provisional
 122-934 9.78e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.18  E-value: 9.78e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  122 EEEFSLDDSSSEQGAQSSQTCLQMVEKELAEKQHDIEElTQELEEMRASFGTEGLKQLQEFEAAIKQRDgiitqlTANLQ 201
Cdd:PTZ00121  1143 EEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEA-ARKAEEVRKAEELRKAEDARKAEAARKAEE------ERKAE 1215

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  202 QARREKDDTMVEFLELTEQSQKlqiQFQHLQANETLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQ 281
Cdd:PTZ00121  1216 EARKAEDAKKAEAVKKAEEAKK---DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA 1292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  282 EKLRafEMEKDRKIENLNAKEIQEKQAliDELNTRVVEEEKKTVELKNKV---TTADELLGGLHEQLTQRNQEIQSLKLE 358
Cdd:PTZ00121  1293 DEAK--KAEEKKKADEAKKKAEEAKKA--DEAKKKAEEAKKKADAAKKKAeeaKKAAEAAKAEAEAAADEAEAAEEKAEA 1368

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  359 LGNSQQNERKCSEEIK---ELMRTVEELQKRNLKDSwLETSAVRRVEQEtQRKLSHLQAELDEMygKQIVQMKQELINQH 435
Cdd:PTZ00121  1369 AEKKKEEAKKKADAAKkkaEEKKKADEAKKKAEEDK-KKADELKKAAAA-KKKADEAKKKAEEK--KKADEAKKKAEEAK 1444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  436 MSQIEELKSQHKREMENTLKSDTNAAISKEQVNLMNAA--INELNVRLQETHAQKEELKGelgvvlgeksalQSQSNDLL 513
Cdd:PTZ00121  1445 KADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAkkADEAKKKAEEAKKKADEAKK------------AAEAKKKA 1512

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  514 EEVRFLREQVQKARQTIAEQENRLSEARKSlstVEDLKAEIVAASESRKELELKHEAEitnykiKLEMLEKEKNAVLDRM 593
Cdd:PTZ00121  1513 DEAKKAEEAKKADEAKKAEEAKKADEAKKA---EEKKKADELKKAEELKKAEEKKKAE------EAKKAEEDKNMALRKA 1583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  594 AESQEAELERLRTQLLFSHEEELSKLKE-DLEVEHRINIEKLKDNLGIHYK-QQIDGLQNEMNRKMESMQCETDNLITQQ 671
Cdd:PTZ00121  1584 EEAKKAEEARIEEVMKLYEEEKKMKAEEaKKAEEAKIKAEELKKAEEEKKKvEQLKKKEAEEKKKAEELKKAEEENKIKA 1663

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  672 NQLILENSKLRDLQECLVNSKSEEMNLQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEkcaq 751
Cdd:PTZ00121  1664 AEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEA---- 1739

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  752 ldaennilKEEKRVLEDKLKmyspSEQEERSIAVDPSTSKSADSRWQKEVAMLRKETEDLQQQCLYLNEEiEKQRNTFAf 831
Cdd:PTZ00121  1740 --------EEDKKKAEEAKK----DEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVD-KKIKDIFD- 1805

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  832 aekNFEvNYQELQREYTCLLKIRDDLEATQTKQALEYESKLRALEEELLSKRGNPAAPKGKSSGI---FPSETleigEVV 908
Cdd:PTZ00121  1806 ---NFA-NIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKeadFNKEK----DLK 1877

                          810       820
                   ....*....|....*....|....*.
gi 1039770159  909 EKDTTELMEKLEVTKREKLELSEKVS 934
Cdd:PTZ00121  1878 EDDEEEIEEADEIEKIDKDDIEREIP 1903
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1809-2281 1.30e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.59  E-value: 1.30e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1809 RLQAAVEKLLEAISETNTQLEHAKVTQTELMRES-------FRQKQEATESLHCLEELRERLQEESRAREQLAEELNKAE 1881
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELeeaqaeeYELLAELARLEQDIARLEERRRELEERLEELEEELAELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1882 SVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEAGpVEQQFLQETEKL 1961
Cdd:COG1196    330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAA-ELAAQLEELEEA 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1962 MKEKLEVQCQAEKVRGDLQKQVKALEIDVEEQVSRFIEL------EQEKNAELTDLRQQSQALEKQLEKMRKFLDEQAID 2035
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAaeeeaeLEEEEEALLELLAELLEEAALLEAALAELLEELAE 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2036 REHERDVFQQEIQKLEHQLKAVPRIQPVSE----HQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLEC 2111
Cdd:COG1196    489 AAARLLLLLEAEADYEGFLEGVKAALLLAGlrglAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2112 RV--RELEQALLASAEPFPKVEDQKR-----------SGAVEADPELSLEVQLQVERDATDRKQKEITNLEEQLEQFREE 2178
Cdd:COG1196    569 AKagRATFLPLDKIRARAALAAALARgaigaavdlvaSDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLRE 648

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2179 LENKNDEVQELLMQLEIQRKESTTRLQELQQENRLFKviEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEK 2258
Cdd:COG1196    649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA--ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEAL 726

                          490       500
                   ....*....|....*....|...
gi 1039770159 2259 LQQEVVSTEQQREGARTLPEDEE 2281
Cdd:COG1196    727 EEQLEAEREELLEELLEEEELLE 749
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2966-3301 1.73e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.73e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2966 EMQLELSSLRDRAAELQEQLSS--------EKmvVAELKSELAQAKLELG-----------TTLKAQHKRLK-ELEAFRS 3025
Cdd:COG1196    183 ATEENLERLEDILGELERQLEPlerqaekaER--YRELKEELKELEAELLllklreleaelEELEAELEELEaELEELEA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3026 EVKEKTDEIHFLSDTLAREQKNSLELQWALEKEKARSGHHEGREKEELEDLKFSLEDQKRRNTQLNLLLEQQKQLLNESQ 3105
Cdd:COG1196    261 ELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELE 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3106 QKIESQKMLHDAQLSEEQGRNLGLQALLESEQVRIQEMKSTLDKERELYAQLQSREDggqpppalpsedlLKELQKQLEE 3185
Cdd:COG1196    341 ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE-------------LAAQLEELEE 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3186 KHSRIVELLSETEKYKLDSLQTRQQMEKDRQVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQQVYKLDLEGK 3265
Cdd:COG1196    408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELA 487

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 1039770159 3266 RLQGLMQEFQKQELEPEEKPGSRGLVDQNLNEPATW 3301
Cdd:COG1196    488 EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 139-845 3.03e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 66.92  E-value: 3.03e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  139 SQTCLQMVEKELAEKQHDIEELTQELEEMRASFGTEGLKQLQEFEAAIKQRDGIITQLTANLQQARREKDDTMVEFLELT 218
Cdd:pfam02463  319 SEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE 398

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  219 EQSQKLQIQFQHLQANETLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEMEKDRKIENL 298
Cdd:pfam02463  399 LKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ 478

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  299 NAKEI--QEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNsqQNERKCSEEIKEL 376
Cdd:pfam02463  479 LVKLQeqLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKV--AISTAVIVEVSAT 556

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  377 MRTVEELQKRNLKDSWLETSAVRRVEQETQRKLSHLQAELDEMYGKQIVQMKQELINQHMSQIEELKSQHKREMENTLKS 456
Cdd:pfam02463  557 ADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTK 636

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  457 DTNAAISKEQVNLMNAAINELNVRLQETHAQKEELKGELGVVLgEKSALQSQSNDLLEEVRFLREQVQKARQTIAEQENR 536
Cdd:pfam02463  637 LKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQ-ELQEKAESELAKEEILRRQLEIKKKEQREKEELKKL 715

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  537 LSEARKSL----STVEDLKAEIVAASESRKELELKHEAEITNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSH 612
Cdd:pfam02463  716 KLEAEELLadrvQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEK 795

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  613 EEELSKLKEDLEVEHRINIEKLK-DNLGIHYKQQIDGLQNEMNRKMESMQCETDNLITQQNQLILENSKLRDLqeclvNS 691
Cdd:pfam02463  796 LKAQEEELRALEEELKEEAELLEeEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEEL-----LQ 870

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  692 KSEEMNLQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAENNILKEEKRVLEDKLK 771
Cdd:pfam02463  871 ELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEK 950

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039770159  772 MYSPSEQEERSIAVDPSTSKSAdsrwQKEVAMLRKETEDLQQQclYLNEEIEKQRNTFAFAEKNFEVNYQELQR 845
Cdd:pfam02463  951 EENNKEEEEERNKRLLLAKEEL----GKVNLMAIEEFEEKEER--YNKDELEKERLEEEKKKLIRAIIEETCQR 1018
PTZ00121 PTZ00121
MAEBL; Provisional
 2943-3280 1.25e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.70  E-value: 1.25e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2943 REQGTEKSSQELLDCSMQQKQSLEMQLELSSLRDRAAELQEQlSSEKMVVAELKSELAQAKLELGTTLKAQHKRLKELEA 3022
Cdd:PTZ00121  1437 KKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKK-AEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEA 1515

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3023 FRSEVKEKTDEIHflsdtLAREQKNSLELQWALEKEKARsghhegrEKEELEDLKFSLEDQKRRNTQLNLLLEQQKQLLN 3102
Cdd:PTZ00121  1516 KKAEEAKKADEAK-----KAEEAKKADEAKKAEEKKKAD-------ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKA 1583

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3103 ESQQKIESQKMLHDAQLSEEQGRNLGLQALLESEQVRIQEMKSTLDKERELYAQLQSREdggqpppalpSEDLLK--ELQ 3180
Cdd:PTZ00121  1584 EEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKE----------AEEKKKaeELK 1653

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3181 KQLEEKHSRIVELLSETEKYKLDSLQTRQQMEKDRQVHQKTLQTEQEANT--QGQKKMQELQSKVEELQRQLQEKRQQVY 3258
Cdd:PTZ00121  1654 KAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKaeELKKKEAEEKKKAEELKKAEEENKIKAE 1733

                          330       340
                   ....*....|....*....|..
gi 1039770159 3259 KLDLEGKRLQGLMQEFQKQELE 3280
Cdd:PTZ00121  1734 EAKKEAEEDKKKAEEAKKDEEE 1755
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1957-2251 7.81e-08

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 58.60  E-value: 7.81e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1957 ETEKLMKEKLEVQCQAEKvRGDLQKQVKALEIDVEEQVSRFIELEQ---EKNAELTDLRQQSQALEKQLEKMRKFLDEQA 2033
Cdd:pfam17380  297 EQERLRQEKEEKAREVER-RRKLEEAEKARQAEMDRQAAIYAEQERmamERERELERIRQEERKRELERIRQEEIAMEIS 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2034 IDREHERDVF--QQEIQKLEHQLKAVPRIQPVSEHQAREVEQLTNHLKEKtdRCSELLLSKEQLQRDIQERNEEIEklec 2111
Cdd:pfam17380  376 RMRELERLQMerQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQI--RAEQEEARQREVRRLEEERAREME---- 449

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2112 RVRELEQALLASAEPFPKVEDQKRSGAVEADPELSLEVQLQ------VERDATDRKQKEItnleeQLEQFREELENKNDE 2185
Cdd:pfam17380  450 RVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEeqrrkiLEKELEERKQAMI-----EEERKRKLLEKEMEE 524

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770159 2186 VQELLMQLEIQRKESTTRLQELQQENRlfKVIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQ 2251
Cdd:pfam17380  525 RQKAIYEEERRREAEEERRKQQEMEER--RRIQEQMRKATEERSRLEAMEREREMMRQIVESEKAR 588
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2897-3198 2.86e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.99  E-value: 2.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2897 LEQRIQEQGIEYHTAMDCLQ--KADRRSLLAEIEDLRAQINGGKMTLER-----EQGTEKSSQELLDCSMQQKQSLEMQL 2969
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEelEEELEQLRKELEELSRQISALRKDLARleaevEQLEERIAQLSKELTELEAEIEELEE 768

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2970 ELSSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELgTTLKAQHKRLKE--------LEAFRSEVKEKTDEIHFLSDTL 3041
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREAL-DELRAELTLLNEeaanlrerLESLERRIAATERRLEDLEEQI 847

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3042 AREQKNSLELQWALEKEKArsghhegrEKEELEDLKFSLEDQKRRNTQLNLLLEQQKQLLNESQQKIESQKMLHDAQLSE 3121
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEE--------LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE 919

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039770159 3122 EQGRNLGLQALLESEQVRIQEMKSTLdkeRELYaQLQSREDGGQPPPALPSEDLLKELQKQLEEKHSRI--VELLSETE 3198
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDNLQERL---SEEY-SLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpVNLAAIEE 994
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 2960-3284 3.66e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.17  E-value: 3.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2960 QQKQSLEMQLELSSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELGTTLkaqhKRLKELEAFRSEVKEKTDEIhflsd 3039
Cdd:pfam01576  199 EEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAAL----ARLEEETAQKNNALKKIREL----- 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3040 tlareQKNSLELQWALEKEKARSGHHEGREK---EELEDLKFSLEDQKRRNTQLNLLLEQQKQLLNESQQKIESQKMLHD 3116
Cdd:pfam01576  270 -----EAQISELQEDLESERAARNKAEKQRRdlgEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3117 AQLSE-EQGRNLGLQALLES-EQVR-----IQEMKSTLDKER-ELYAQLQSREDGGQpppalPSEDLLKELQKQLEEKHS 3188
Cdd:pfam01576  345 AQLQEmRQKHTQALEELTEQlEQAKrnkanLEKAKQALESENaELQAELRTLQQAKQ-----DSEHKRKKLEGQLQELQA 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3189 RivelLSETEKYKLDSLQTRQQMEKDRQVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQQVYKLDLEGKRLQ 3268
Cdd:pfam01576  420 R----LSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLE 495

                          330
                   ....*....|....*.
gi 1039770159 3269 GLMQEFQKQELEPEEK 3284
Cdd:pfam01576  496 DERNSLQEQLEEEEEA 511
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 643-768 4.46e-05

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 48.48  E-value: 4.46e-05
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159   643 KQQIDGLQNEMNRKMESMQCETDNLITQQNQLileNSKLRDLQECLVNSKSEEMNLQinELQKEIEILKQEE----KEK- 717
Cdd:smart00787  139 MKLLEGLKEGLDENLEGLKEDYKLLMKELELL---NSIKPKLRDRKDALEEELRQLK--QLEDELEDCDPTEldraKEKl 213

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|.
gi 1039770159   718 GTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAENNILKEEKRVLED 768
Cdd:smart00787  214 KKLLQEIMIKVKKLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQ 264
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 2132-2262 1.75e-04

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 46.93  E-value: 1.75e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  2132 DQKRSGAVEADPELSLEVQLQVE-----RDATDRKQKEITNLEEQLEQFRE----ELENKNDEVQELLMQLEIQRKESTT 2202
Cdd:smart00787  150 DENLEGLKEDYKLLMKELELLNSikpklRDRKDALEEELRQLKQLEDELEDcdptELDRAKEKLKKLLQEIMIKVKKLEE 229

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  2203 RLQELQQenrLFKVIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQE 2262
Cdd:smart00787  230 LEEELQE---LESKIEDLTNKKSELNTEIAEAEKKLEQCRGFTFKEIEKLKEQLKLLQSL 286
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1523-1708 4.33e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.19  E-value: 4.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1523 VRKSMHDEVLVSSMDTSRQLILNEQLEDMRQELVRQYEEHQQATEMLRQAHMQQMERQREDQEQLQEEIKRLNEQLA--- 1599
Cdd:pfam17380  394 VRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEerk 473

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1600 ------QKSSIDTEHVVSERERVLLEELEALKQLPLA---GRKELCCELRHSSTQTQDGHDDQEVEEQTLKDKTLERSPE 1670
Cdd:pfam17380  474 rkklelEKEKRDRKRAEEQRRKILEKELEERKQAMIEeerKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRR 553

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1039770159 1671 DALLDRNLSNERYALkKANNRLLKILLEVVKTTSAAEE 1708
Cdd:pfam17380  554 IQEQMRKATEERSRL-EAMEREREMMRQIVESEKARAE 590
 
Name Accession Description Interval E-value
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 3534-3615 4.34e-21

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


Pssm-ID: 463115  Cd Length: 77  Bit Score: 89.57  E-value: 4.34e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3534 KYLRASSFRKALIYQKKYLLLLLGGFQECEDVTLGVLARMGGHLALKDSKtitnhPKAFSRFRSAVRVSIAISRMKFLVR 3613
Cdd:pfam10495    1 KLLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDDRPS-----RKPRRKLKSAALAVIAIARMKRLAR 75


                   ..
gi 1039770159 3614 RW 3615
Cdd:pfam10495   76 EW 77
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 156-964 5.65e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.96  E-value: 5.65e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  156 DIEELTQELEEMRASFgTEGLKQLQEFEAAIKQRDGIITQLTANLQQARREKDDTMVEFLELTEQSQKLQIQFQHLQANE 235
Cdd:TIGR02168  233 RLEELREELEELQEEL-KEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  236 TLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEMEKdrkiENLNAKeIQEKQALIDELNT 315
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL----EELESR-LEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  316 RVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQNE--RKCSEEIKELMRTVEELQKRNLKDSWL 393
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKElqAELEELEEELEELQEELERLEEALEEL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  394 ETS--AVRRVEQETQRKLSHLQAELDEM-----------YGKQIVQMKQELINQHMSQIEEL---KSQHKREMENTLKSD 457
Cdd:TIGR02168  467 REEleEAEQALDAAERELAQLQARLDSLerlqenlegfsEGVKALLKNQSGLSGILGVLSELisvDEGYEAAIEAALGGR 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  458 TNAAISK------------EQVNLMNAAINELNV-RLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQ 524
Cdd:TIGR02168  547 LQAVVVEnlnaakkaiaflKQNELGRVTFLPLDSiKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVL 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  525 KArQTIAEQENRLSEARKSLSTVEdLKAEIVAASESRKELELKHEAEITNYKIKLEMLEKEKNAVLDRMAEsQEAELERL 604
Cdd:TIGR02168  627 VV-DDLDNALELAKKLRPGYRIVT-LDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAE-LEKALAEL 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  605 RTQLlfsheEELSKLKEDLEVEhrinieklkdnlgihyKQQIDGLQNEMNRKMESMQCETDNLITQQNQLILENSKLRDl 684
Cdd:TIGR02168  704 RKEL-----EELEEELEQLRKE----------------LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA- 761

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  685 qeclvnskseemnlQINELQKEIEILKQEEKEkgtLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAenniLKEEKR 764
Cdd:TIGR02168  762 --------------EIEELEERLEEAEEELAE---AEAEIEELEAQIEQLKEELKALREALDELRAELTL----LNEEAA 820

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  765 VLEDKLkmyspsEQEERSIAvdpstsksadsRWQKEVAMLRKETEDLQQQCLYLNEEIEKQRNTFAFAEKNFEVNYQELQ 844
Cdd:TIGR02168  821 NLRERL------ESLERRIA-----------ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  845 REYTCLLKIRDDLEATQTKQAlEYESKLRALEEELLSKRGNPAAPKGKSSGIfpseTLEIGEVVEKdtteLMEKLEVTKR 924
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELR-ELESKRSELRRELEELREKLAQLELRLEGL----EVRIDNLQER----LSEEYSLTLE 954

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 1039770159  925 EKLELSEKVSGLSEQLKQthctinslsaEVRALKQEKEQL 964
Cdd:TIGR02168  955 EAEALENKIEDDEEEARR----------RLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1798-2460 4.14e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 4.14e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1798 ENEELMLNISSRLQAAVEKLLE---AISETNTQLEHAKVTQTELMRESFR---QKQEATESLHCLEELRERLQEES---- 1867
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEElrlEVSELEEEIEELQKELYALANEISRleqQKQILRERLANLERQLEELEAQLeele 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1868 RAREQLAEELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEA 1947
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARL 409

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1948 GPVE---QQFLQETEKLMKEKLEVQcqAEKVRGDLQKQVKALEiDVEEQVSRFIELEQEKNAELTDLRQQSQALEKQLEK 2024
Cdd:TIGR02168  410 ERLEdrrERLQQEIEELLKKLEEAE--LKELQAELEELEEELE-ELQEELERLEEALEELREELEEAEQALDAAERELAQ 486

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2025 MRKFLDEQAIDREHERDVFQQEIQKLEHQLKAVPRIQPVSEH-------------------QAREVEQLT------NHLK 2079
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyeaaieaalggrlQAVVVENLNaakkaiAFLK 566

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2080 EKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQALLASAEPFPKV------------------EDQKRSGA--- 2138
Cdd:TIGR02168  567 QNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvvddldnalELAKKLRPgyr 646

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2139 -VEADPELSLEVQLQVERDATDR-----KQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENR 2212
Cdd:TIGR02168  647 iVTLDGDLVRPGGVITGGSAKTNssileRRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSR 726

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2213 LfkvIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQREGARTLPEDEESFKHQLDKVTA 2292
Cdd:TIGR02168  727 Q---ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2293 EKLVLEQQVETTNQVMTHMNNVLKEINFKMDQITQSLCNLNKECASNEelpslpkESVHMTVHELGSDNLQPEDAPAQ-- 2370
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS-------EDIESLAAEIEELEELIEELESEle 876

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2371 DVTKPLEKQTSLTRLQKSPEASRTQEIESLASSVGAKDVELTQCREQTETIQ---EQAQSETDRLQKKLTDLQRSLEKFA 2447
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLElrlEGLEVRIDNLQERLSEEYSLTLEEA 956

                          730
                   ....*....|...
gi 1039770159 2448 AALVSQVQMEAAQ 2460
Cdd:TIGR02168  957 EALENKIEDDEEE 969
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 146-747 3.85e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.60  E-value: 3.85e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  146 VEKELAEKQHDIEELTQELEEMRAsfgteglkQLQEFEAAIKQRDGIITQLTANLQQARRekddtmvEFLELTEQSQKLQ 225
Cdd:COG1196    237 LEAELEELEAELEELEAELEELEA--------ELAELEAELEELRLELEELELELEEAQA-------EEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  226 IQFQHLQANETLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEMEKDRKIEnlnakEIQE 305
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA-----ELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  306 KQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEIKELMRTVEELQK 385
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  386 RNLKDSwLETSAVRRVEQETQRKLSHLQAELDEMygKQIVQMKQELINQHMSQIEELKSQHKREMENTLKSDTNAAISKE 465
Cdd:COG1196    457 EEEALL-ELLAELLEEAALLEAALAELLEELAEA--AARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  466 QV------NLMNAAINELNVRLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKARQTIAEQENRLSE 539
Cdd:COG1196    534 AAyeaaleAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  540 ARKSLSTVEDLKAEIVAASESRKELELKHEAEITnyKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKL 619
Cdd:COG1196    614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR--EVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  620 KEDLEVEHRINIEKLKDnlgihyKQQIDGLQNEMNRKMESMQCETDNLITQQNQLILENSKLRDLQEclvnSKSEEMNLQ 699
Cdd:COG1196    692 ELELEEALLAEEEEERE------LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA----LEELPEPPD 761

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1039770159  700 INELQKEIEILKQEEKEKGTL----EQEVQELQlktEQLEKqLKEKEDDLQE 747
Cdd:COG1196    762 LEELERELERLEREIEALGPVnllaIEEYEELE---ERYDF-LSEQREDLEE 809
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 268-973 5.28e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.95  E-value: 5.28e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  268 KKEEDLQAQIS-----FLQEKLRAFEMEKDRkienlNAKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLH 342
Cdd:TIGR02168  220 AELRELELALLvlrleELREELEELQEELKE-----AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  343 EQLTQRNQEIQSLKLELGNSQQNERKCSEEIKELMRTVEELQKrnlkdswlETSAVRRVEQETQRKLSHLQAELDEMygK 422
Cdd:TIGR02168  295 NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE--------ELAELEEKLEELKEELESLEAELEEL--E 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  423 QIVQMKQELINQHMSQIEELKSQhKREMENTLKSDTNaaiskeQVNLMNAAINELNVRLQETHAQKEELKGELgvVLGEK 502
Cdd:TIGR02168  365 AELEELESRLEELEEQLETLRSK-VAQLELQIASLNN------EIERLEARLERLEDRRERLQQEIEELLKKL--EEAEL 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  503 SALQSQSNDLLEEVRFLREQVQKARQTIAEQENRLSEARKSLSTVEDLKAEIVAASESRKELELKHEaEITNYKIKLEML 582
Cdd:TIGR02168  436 KELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLE-GFSEGVKALLKN 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  583 EKEKNAVLDRMAESQEAElERLRTQLlfshEEELSKLKEDLEVE----HRINIEKLKDN---------LGIHYKQQIDGL 649
Cdd:TIGR02168  515 QSGLSGILGVLSELISVD-EGYEAAI----EAALGGRLQAVVVEnlnaAKKAIAFLKQNelgrvtflpLDSIKGTEIQGN 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  650 QNEMNRKMESMQCETDNLITQQNQL-------------------ILENSKLRDLQECLV-------------NSKSEEMN 697
Cdd:TIGR02168  590 DREILKNIEGFLGVAKDLVKFDPKLrkalsyllggvlvvddldnALELAKKLRPGYRIVtldgdlvrpggviTGGSAKTN 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  698 LQINELQKEIEilkqeekekgTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAENNILKEEKRVLEDKLKMYSPSE 777
Cdd:TIGR02168  670 SSILERRREIE----------ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLE 739

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  778 QEERSIAVDPSTSKSADSRWQKEVAMLRKETEDLQQQCLYLNEEIEKQRNTFAFAEKNFEVN---YQELQREYTCLLKIR 854
Cdd:TIGR02168  740 AEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALreaLDELRAELTLLNEEA 819

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  855 DDLEATQTKQALEYESKLRALEEELLSKRGNPAAPKGKSSGIFPSETLEigEVVEKDTTELMEKLEVTKREKLELSEKVS 934
Cdd:TIGR02168  820 ANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELI--EELESELEALLNERASLEEALALLRSELE 897

                          730       740       750
                   ....*....|....*....|....*....|....*....
gi 1039770159  935 GLSEQLKQTHCTINSLSAEVRALKQEKEQLLLRCGELEL 973
Cdd:TIGR02168  898 ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEV 936
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1989-2302 7.27e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.56  E-value: 7.27e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1989 DVEEQVSRFIELEQEKNAELTDLRQQSQALEKQLEKMRKFLDEQaidrehERDVFQQEIQKLEHQLKavpriqpvSEHQA 2068
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------SRQISALRKDLARLEAE--------VEQLE 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2069 REVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQALLASAEPFPKVEDQKRSGAVEAdpeLSLE 2148
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEA---ANLR 823

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2149 VQLQVERDATDRKQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENRLFKVIEEQKEQIQDLE 2228
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEEL 903

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039770159 2229 TQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQ-REGARTLPEDEESFKhqlDKVTAEKLVLEQQVE 2302
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlSEEYSLTLEEAEALE---NKIEDDEEEARRRLK 975
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 143-655 8.04e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.44  E-value: 8.04e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  143 LQMVEKELAEKQHDIEELTQELEEMRASFgTEGLKQLQEFEAAI-------KQRDGIITQLTANLQQARREKDDTMVEFL 215
Cdd:COG1196    262 LAELEAELEELRLELEELELELEEAQAEE-YELLAELARLEQDIarleerrRELEERLEELEEELAELEEELEELEEELE 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  216 ELTEQSQKLQIQFQHLQANETLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEMEKDRKI 295
Cdd:COG1196    341 ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLE 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  296 ENLNA--KEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEI 373
Cdd:COG1196    421 EELEEleEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  374 KELMRTVEELQKRNLKDSWLETSAVRRVEQETQRKLSHLQAELDEMYGKQIVqmkQELINQHMSQIEELKSQHKREMEnT 453
Cdd:COG1196    501 ADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV---VEDDEVAAAAIEYLKAAKAGRAT-F 576

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  454 LKSDTNAAISKEQVNLMNAAINELNVRLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKARQTIAEQ 533
Cdd:COG1196    577 LPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGG 656

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  534 ENRLSEARKSLSTVEDLKAEIVAASESRKELELKHEAEITNYKIKLEMLEKEKNAVLDRMAEsQEAELERLRTQLLFSHE 613
Cdd:COG1196    657 SAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLE-EELEEEALEEQLEAERE 735

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|...
gi 1039770159  614 EELSKLKEDLEVEHRINIEKLKDNLGIH-YKQQIDGLQNEMNR 655
Cdd:COG1196    736 ELLEELLEEEELLEEEALEELPEPPDLEeLERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 120-767 1.61e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.40  E-value: 1.61e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  120 LREEEFSLDDSSSEQGAQSSQTCLQM--VEKELAEKQHDIEELTQELEEMRasfgteglKQLQEFEAAIKQRDGIITQLT 197
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVseLEEEIEELQKELYALANEISRLE--------QQKQILRERLANLERQLEELE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  198 ANLQQARREKDDTMVEFLELTEQSQKLQIQFQHLQA-----NETLQNST---------LSRTATDLLQAKRQIFTQQQQL 263
Cdd:TIGR02168  323 AQLEELESKLDELAEELAELEEKLEELKEELESLEAeleelEAELEELEsrleeleeqLETLRSKVAQLELQIASLNNEI 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  264 QDYQKKEEDLQAQISFLQEKLRAFEMEKDRKIENLNAKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHE 343
Cdd:TIGR02168  403 ERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAER 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  344 QLTQRNQEIQSLKlelgNSQQNERKCSEEIKELMrtveeLQKRNLKDSWLETSAVRRVEQETQRKLS-----HLQA---E 415
Cdd:TIGR02168  483 ELAQLQARLDSLE----RLQENLEGFSEGVKALL-----KNQSGLSGILGVLSELISVDEGYEAAIEaalggRLQAvvvE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  416 LDEMYGKQIVQMKQELINQHM----SQIEELKSQhKREMENTLKSDTNAAISKEQVNLMNAAINELNVRL---------- 481
Cdd:TIGR02168  554 NLNAAKKAIAFLKQNELGRVTflplDSIKGTEIQ-GNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvddld 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  482 QETHAQKEELKGELGVVL-GE---KSALQSQSNDLLEEVRFLREQ-VQKARQTIAEQENRLSEARKSLSTVEDLKAEIVA 556
Cdd:TIGR02168  633 NALELAKKLRPGYRIVTLdGDlvrPGGVITGGSAKTNSSILERRReIEELEEKIEELEEKIAELEKALAELRKELEELEE 712

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  557 ASESRKELELKHEAEITNYKIKLEMLEKEKNAVLDRMAESQE--AELERLRTQLLFSHEEELSKLKEDLEVEHRIN--IE 632
Cdd:TIGR02168  713 ELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKelTELEAEIEELEERLEEAEEELAEAEAEIEELEaqIE 792

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  633 KLKDNLGIhYKQQIDGLQNEMNRKMESMQCETDNLITQQNQLILENSKLRDLQECLVNSKS--EEMNLQINELQKEIEIL 710
Cdd:TIGR02168  793 QLKEELKA-LREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEdiESLAAEIEELEELIEEL 871

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039770159  711 KQE----EKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAENNILKEEKRVLE 767
Cdd:TIGR02168  872 ESElealLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE 932
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 180-768 2.04e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.90  E-value: 2.04e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  180 QEFEAAIKQRDGIITQLTANLQQARREkddtmveflELTEQSQKLQIQFQHLQANETLQNSTLSRTATDLLQAKRQIFTQ 259
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELE---------ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  260 QQQLQDYQKKEEDLQAQISFLQEKLRAFEMEKDRKIENLN--AKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADEL 337
Cdd:COG1196    287 QAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAelEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  338 LGGLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEIKELMRTVEELQKRNLKDSWLETSAVRRVEQETQRKLSHLQAELD 417
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  418 EmygKQIVQMKQELINQHMSQIEELKSQHKREMENTLKSDTNAAISKEQVNLMNAAINELN-----VRLQETHAQKEELK 492
Cdd:COG1196    447 A---AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflegVKAALLLAGLRGLA 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  493 GELGVVLGEKSALQSQSNDLLEEVrfLREQVQKARQTIAEQENRLSEARKSLSTVEDL-KAEIVAASESRKELELKHEAE 571
Cdd:COG1196    524 GAVAVLIGVEAAYEAALEAALAAA--LQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLdKIRARAALAAALARGAIGAAV 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  572 ITNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEVEH----RINIEKLKDNLGIHYKQQID 647
Cdd:COG1196    602 DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSaggsLTGGSRRELLAALLEAEAEL 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  648 GLQNEMNRKMESMQCETDNLITQQNQLILENSKLRDLQECLV----NSKSEEMNLQINELQKEIEILKQEEKEKGTLEQE 723
Cdd:COG1196    682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEealeEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1039770159  724 VQELQLKTEQLEKQLKEKE----------DDLQEKCAQLDAENNILKEEKRVLED 768
Cdd:COG1196    762 LEELERELERLEREIEALGpvnllaieeyEELEERYDFLSEQREDLEEARETLEE 816
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1809-2293 6.24e-13

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 75.46  E-value: 6.24e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1809 RLQAAVEKLLEAISETNTQLEHAKVTQTEL--MRESFRQKQEATESLhcleelrerlqeesrareqlAEELNKAESVIDG 1886
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEAdeVLEEHEERREELETL--------------------EAEIEDLRETIAE 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1887 YSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMR---AEAGPVEQQFLQETEKLMK 1963
Cdd:PRK02224   270 TEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRdrlEECRVAAQAHNEEAESLRE 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1964 EKLEVQCQAEKVR---GDLQKQVKALEIDVEEQVSRFIELEqeknAELTDLRQQSQALEKQLEKMRKFLDEqaidREHER 2040
Cdd:PRK02224   350 DADDLEERAEELReeaAELESELEEAREAVEDRREEIEELE----EEIEELRERFGDAPVDLGNAEDFLEE----LREER 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2041 DVFQQEIQKLEHQLKAVpriqpvsEHQAREVEQLTNHLK-----------EKTDRCSELLLSKEQLQRDIQERNEEIEKL 2109
Cdd:PRK02224   422 DELREREAELEATLRTA-------RERVEEAEALLEAGKcpecgqpvegsPHVETIEEDRERVEELEAELEDLEEEVEEV 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2110 ECRVRELEQALLASAEPFPKVEDQKRSGAVEADPELSLEVQlqveRDATDRKQKEITNLEEQLEQFRE---ELENKNDEV 2186
Cdd:PRK02224   495 EERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEK----RERAEELRERAAELEAEAEEKREaaaEAEEEAEEA 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2187 QELLMQLEIQRKESTTRLQELQQenrlfkvIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEVVST 2266
Cdd:PRK02224   571 REEVAELNSKLAELKERIESLER-------IRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEF 643

                          490       500
                   ....*....|....*....|....*...
gi 1039770159 2267 EQQR-EGARtlpEDEESFKHQLDKVTAE 2293
Cdd:PRK02224   644 DEARiEEAR---EDKERAEEYLEQVEEK 668
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 147-972 8.86e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.10  E-value: 8.86e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  147 EKELAEKQHDIEELTQELEemrasfGTEGLKQLQEFEAAIKQRDGIITQLTANLQQARREKDDTMVEFLELTEQSQKLQI 226
Cdd:TIGR02169  206 EREKAERYQALLKEKREYE------GYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNK 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  227 QFQHLQANETLQ-NSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEmekdrkienlnaKEIQE 305
Cdd:TIGR02169  280 KIKDLGEEEQLRvKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE------------REIEE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  306 KQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEIKELMRTVEEL-- 383
Cdd:TIGR02169  348 ERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLna 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  384 ------QKRNLKDSWLETSAVRRVEQEtqRKLSHLQAELDEmYGKQIVQMKQELinqhmSQIEELKSQHKREMEntlKSD 457
Cdd:TIGR02169  428 aiagieAKINELEEEKEDKALEIKKQE--WKLEQLAADLSK-YEQELYDLKEEY-----DRVEKELSKLQRELA---EAE 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  458 TNAAISKEQVNLMNAAINELNVRLQETHAqkeeLKGELGVVlGEK--SALQSQSNDLLEEVRFLREQVQKARQTIAEQEN 535
Cdd:TIGR02169  497 AQARASEERVRGGRAVEEVLKASIQGVHG----TVAQLGSV-GERyaTAIEVAAGNRLNNVVVEDDAVAKEAIELLKRRK 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  536 rlsEARKSLSTVEDLKAEivaasesRKELELKHEAEITNYKIKL-EMLEKEKNA---------VLDRMAESQ-------- 597
Cdd:TIGR02169  572 ---AGRATFLPLNKMRDE-------RRDLSILSEDGVIGFAVDLvEFDPKYEPAfkyvfgdtlVVEDIEAARrlmgkyrm 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  598 ---EAEL-----------ERLRTQLLFSHEEElsklKEDLEVEHRinIEKLKDNLGIhYKQQIDGLQNEMNRKMESMQCE 663
Cdd:TIGR02169  642 vtlEGELfeksgamtggsRAPRGGILFSRSEP----AELQRLRER--LEGLKRELSS-LQSELRRIENRLDELSQELSDA 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  664 TDNLITQQNQLILENSKLRDLQECLVNSKSeemnlQINELQKEIEILKQEEKEkgtLEQEVQELQLKTEQLEKQLKEKED 743
Cdd:TIGR02169  715 SRKIGEIEKEIEQLEQEEEKLKERLEELEE-----DLSSLEQEIENVKSELKE---LEARIEELEEDLHKLEEALNDLEA 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  744 DL-QEKCAQLDAENNILKEEKRVLE---DKLKMYSPSEQEERSIAVDPSTSKSADSR-WQKEVAMLRKETEDLQQQCLYL 818
Cdd:TIGR02169  787 RLsHSRIPEIQAELSKLEEEVSRIEarlREIEQKLNRLTLEKEYLEKEIQELQEQRIdLKEQIKSIEKEIENLNGKKEEL 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  819 NEEIEKQRNtfafAEKNFEVNYQELQREytcllkiRDDLEAtqtkQALEYESKLRALEEELLSKRGNPAAPKGKSSGIFp 898
Cdd:TIGR02169  867 EEELEELEA----ALRDLESRLGDLKKE-------RDELEA----QLRELERKIEELEAQIEKKRKRLSELKAKLEALE- 930

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  899 SETLEIGEVVEKDTTELMEK--LEVTKREKLELSEKVSGLS-------EQLKQTHCTINSLSAEVRALKQEKEQLLLRCG 969
Cdd:TIGR02169  931 EELSEIEDPKGEDEEIPEEElsLEDVQAELQRVEEEIRALEpvnmlaiQEYEEVLKRLDELKEKRAKLEEERKAILERIE 1010


                   ...
gi 1039770159  970 ELE 972
Cdd:TIGR02169 1011 EYE 1013
PTZ00121 PTZ00121
MAEBL; Provisional
 122-934 9.78e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.18  E-value: 9.78e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  122 EEEFSLDDSSSEQGAQSSQTCLQMVEKELAEKQHDIEElTQELEEMRASFGTEGLKQLQEFEAAIKQRDgiitqlTANLQ 201
Cdd:PTZ00121  1143 EEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEA-ARKAEEVRKAEELRKAEDARKAEAARKAEE------ERKAE 1215

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  202 QARREKDDTMVEFLELTEQSQKlqiQFQHLQANETLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQ 281
Cdd:PTZ00121  1216 EARKAEDAKKAEAVKKAEEAKK---DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA 1292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  282 EKLRafEMEKDRKIENLNAKEIQEKQAliDELNTRVVEEEKKTVELKNKV---TTADELLGGLHEQLTQRNQEIQSLKLE 358
Cdd:PTZ00121  1293 DEAK--KAEEKKKADEAKKKAEEAKKA--DEAKKKAEEAKKKADAAKKKAeeaKKAAEAAKAEAEAAADEAEAAEEKAEA 1368

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  359 LGNSQQNERKCSEEIK---ELMRTVEELQKRNLKDSwLETSAVRRVEQEtQRKLSHLQAELDEMygKQIVQMKQELINQH 435
Cdd:PTZ00121  1369 AEKKKEEAKKKADAAKkkaEEKKKADEAKKKAEEDK-KKADELKKAAAA-KKKADEAKKKAEEK--KKADEAKKKAEEAK 1444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  436 MSQIEELKSQHKREMENTLKSDTNAAISKEQVNLMNAA--INELNVRLQETHAQKEELKGelgvvlgeksalQSQSNDLL 513
Cdd:PTZ00121  1445 KADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAkkADEAKKKAEEAKKKADEAKK------------AAEAKKKA 1512

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  514 EEVRFLREQVQKARQTIAEQENRLSEARKSlstVEDLKAEIVAASESRKELELKHEAEitnykiKLEMLEKEKNAVLDRM 593
Cdd:PTZ00121  1513 DEAKKAEEAKKADEAKKAEEAKKADEAKKA---EEKKKADELKKAEELKKAEEKKKAE------EAKKAEEDKNMALRKA 1583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  594 AESQEAELERLRTQLLFSHEEELSKLKE-DLEVEHRINIEKLKDNLGIHYK-QQIDGLQNEMNRKMESMQCETDNLITQQ 671
Cdd:PTZ00121  1584 EEAKKAEEARIEEVMKLYEEEKKMKAEEaKKAEEAKIKAEELKKAEEEKKKvEQLKKKEAEEKKKAEELKKAEEENKIKA 1663

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  672 NQLILENSKLRDLQECLVNSKSEEMNLQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEkcaq 751
Cdd:PTZ00121  1664 AEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEA---- 1739

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  752 ldaennilKEEKRVLEDKLKmyspSEQEERSIAVDPSTSKSADSRWQKEVAMLRKETEDLQQQCLYLNEEiEKQRNTFAf 831
Cdd:PTZ00121  1740 --------EEDKKKAEEAKK----DEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVD-KKIKDIFD- 1805

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  832 aekNFEvNYQELQREYTCLLKIRDDLEATQTKQALEYESKLRALEEELLSKRGNPAAPKGKSSGI---FPSETleigEVV 908
Cdd:PTZ00121  1806 ---NFA-NIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKeadFNKEK----DLK 1877

                          810       820
                   ....*....|....*....|....*.
gi 1039770159  909 EKDTTELMEKLEVTKREKLELSEKVS 934
Cdd:PTZ00121  1878 EDDEEEIEEADEIEKIDKDDIEREIP 1903
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1868-2260 1.13e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 74.72  E-value: 1.13e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1868 RAREQLAEELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEA 1947
Cdd:TIGR02169  688 RELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARI 767

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1948 GPVEQQFLQETEKLmkEKLEVQCQAEKVRgDLQKQVKALEIDVEEQVSRFIELEQEKNAEltdlrqqsQALEKQLEKMRK 2027
Cdd:TIGR02169  768 EELEEDLHKLEEAL--NDLEARLSHSRIP-EIQAELSKLEEEVSRIEARLREIEQKLNRL--------TLEKEYLEKEIQ 836

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2028 FLDEQAIDREHERDVFQQEIQKLEHQLKAVPRIqpVSEHQArEVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIE 2107
Cdd:TIGR02169  837 ELQEQRIDLKEQIKSIEKEIENLNGKKEELEEE--LEELEA-ALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIE 913

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2108 KLECRVRELEQALLASAEPFPKVEDQKRSGAVEADPELSLEVqlqverdatdrkqkeitnleeqleqfreelenkndevq 2187
Cdd:TIGR02169  914 KKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLED-------------------------------------- 955

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2188 ellMQLEIQRKESttRLQELQQENrlFKVIEEQKE---QIQDLETQIERLMSER--------EHEKKQREEEVEQLTGVV 2256
Cdd:TIGR02169  956 ---VQAELQRVEE--EIRALEPVN--MLAIQEYEEvlkRLDELKEKRAKLEEERkailerieEYEKKKREVFMEAFEAIN 1028


                   ....
gi 1039770159 2257 EKLQ 2260
Cdd:TIGR02169 1029 ENFN 1032
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1809-2281 1.30e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.59  E-value: 1.30e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1809 RLQAAVEKLLEAISETNTQLEHAKVTQTELMRES-------FRQKQEATESLHCLEELRERLQEESRAREQLAEELNKAE 1881
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELeeaqaeeYELLAELARLEQDIARLEERRRELEERLEELEEELAELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1882 SVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEAGpVEQQFLQETEKL 1961
Cdd:COG1196    330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAA-ELAAQLEELEEA 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1962 MKEKLEVQCQAEKVRGDLQKQVKALEIDVEEQVSRFIEL------EQEKNAELTDLRQQSQALEKQLEKMRKFLDEQAID 2035
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAaeeeaeLEEEEEALLELLAELLEEAALLEAALAELLEELAE 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2036 REHERDVFQQEIQKLEHQLKAVPRIQPVSE----HQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLEC 2111
Cdd:COG1196    489 AAARLLLLLEAEADYEGFLEGVKAALLLAGlrglAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2112 RV--RELEQALLASAEPFPKVEDQKR-----------SGAVEADPELSLEVQLQVERDATDRKQKEITNLEEQLEQFREE 2178
Cdd:COG1196    569 AKagRATFLPLDKIRARAALAAALARgaigaavdlvaSDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLRE 648

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2179 LENKNDEVQELLMQLEIQRKESTTRLQELQQENRLFKviEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEK 2258
Cdd:COG1196    649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA--ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEAL 726

                          490       500
                   ....*....|....*....|...
gi 1039770159 2259 LQQEVVSTEQQREGARTLPEDEE 2281
Cdd:COG1196    727 EEQLEAEREELLEELLEEEELLE 749
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1868-2302 3.04e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.05  E-value: 3.04e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1868 RAREQLAEELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEA 1947
Cdd:COG1196    246 AELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1948 GPVEQQFLQETEKLMKEKLEVQcQAEKVRGDLQKQVKALEIDVEEQVSRFIELEQEKNAELTDLRQQSQALEKQLEKMRK 2027
Cdd:COG1196    326 AELEEELEELEEELEELEEELE-EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2028 fLDEQAIDREHERDVFQQEIQKLEHQLKAVpRIQPVSEHQA-----REVEQLTNHLKEKTDRCSELLLSKEQLQRDIQER 2102
Cdd:COG1196    405 -LEEAEEALLERLERLEEELEELEEALAEL-EEEEEEEEEAleeaaEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2103 NEEIEKLEcRVRELEQALLASAEPFP--------KVEDQKRSGAVEADPELSLEVQLQVERDATDRKQKEITNLEEQLEQ 2174
Cdd:COG1196    483 LEELAEAA-ARLLLLLEAEADYEGFLegvkaallLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAA 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2175 FREELENKNDEVQELLMQLEIQRKESTTRLQELQQENRLFKVIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLtg 2254
Cdd:COG1196    562 AIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRA-- 639

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*...
gi 1039770159 2255 vvEKLQQEVVSTEQQREGARTLPEDEESFKHQLDKVTAEKLVLEQQVE 2302
Cdd:COG1196    640 --VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA 685
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 130-877 7.23e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.02  E-value: 7.23e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  130 SSSEQGAQSSQTCLQMVEKELAEKQHDIEELTQELEEMRASFGTEGLKQLQEFEAAIKQRDGIITQLTANLQQARREKDD 209
Cdd:TIGR02169  247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAK 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  210 TMVEFLELTEQSQKLQIQFQHLQANETLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEM 289
Cdd:TIGR02169  327 LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKR 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  290 EKDRKIEnlnakEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQNERKC 369
Cdd:TIGR02169  407 ELDRLQE-----ELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRV 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  370 SEEIKELMRTVEEL--QKRNLKDSWLETSAVRRVEQETQRKLSHLQAEL---DEMYGKQI----------VQMKQELINQ 434
Cdd:TIGR02169  482 EKELSKLQRELAEAeaQARASEERVRGGRAVEEVLKASIQGVHGTVAQLgsvGERYATAIevaagnrlnnVVVEDDAVAK 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  435 hmSQIEELKSQHKREME----NTLKSDTN--AAISKEQVnlMNAAINELN----------------VRLQETHAQKE--- 489
Cdd:TIGR02169  562 --EAIELLKRRKAGRATflplNKMRDERRdlSILSEDGV--IGFAVDLVEfdpkyepafkyvfgdtLVVEDIEAARRlmg 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  490 -----ELKGEL----GVVLG---EKSALQSQSNDLLEEVRFLREQVQK-------ARQTIAEQENRLSEARKSLStveDL 550
Cdd:TIGR02169  638 kyrmvTLEGELfeksGAMTGgsrAPRGGILFSRSEPAELQRLRERLEGlkrelssLQSELRRIENRLDELSQELS---DA 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  551 KAEIVAASESRKELELKHEA---EITNYKIKLEMLEKEKNAVLDRMAESqEAELERLrtqllfshEEELSKLKEDLeveh 627
Cdd:TIGR02169  715 SRKIGEIEKEIEQLEQEEEKlkeRLEELEEDLSSLEQEIENVKSELKEL-EARIEEL--------EEDLHKLEEAL---- 781

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  628 riniEKLKDNLGIHYKQQIDGLQNEMNRKMESMQCETDNLITQQNQLILENSKLRDLQECLVNsKSEEMNLQINELQKEI 707
Cdd:TIGR02169  782 ----NDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQE-QRIDLKEQIKSIEKEI 856

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  708 EILKqeeKEKGTLEQEVQELQLKTEQLEKQLKekedDLQEKCAQLDAENNILKEEKRVLE---DKLKMYSPSEQEERSIA 784
Cdd:TIGR02169  857 ENLN---GKKEELEEELEELEAALRDLESRLG----DLKKERDELEAQLRELERKIEELEaqiEKKRKRLSELKAKLEAL 929

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  785 VDPSTSKSADSRWQKEVAMLRKETEDLQQQCLYLNEEIEKQRntfafaeknfEVNYQELQrEYTCLLKIRDDLEATQTKQ 864
Cdd:TIGR02169  930 EEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALE----------PVNMLAIQ-EYEEVLKRLDELKEKRAKL 998

                          810
                   ....*....|...
gi 1039770159  865 ALEYESKLRALEE 877
Cdd:TIGR02169  999 EEERKAILERIEE 1011
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2008-2302 7.84e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 7.84e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2008 LTDLRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEHQLKavpRIQPVSEHQAREVEQLTNHLKEKTDRCSE 2087
Cdd:COG1196    195 LGELERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELE---ELEAELEELEAELEELEAELAELEAELEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2088 LLLSKEQLQRDIQERNEEIEKLECRVRELEQALlasaepfpKVEDQKRSgaveadpelSLEVQLQVERDATDRKQKEITN 2167
Cdd:COG1196    272 LRLELEELELELEEAQAEEYELLAELARLEQDI--------ARLEERRR---------ELEERLEELEEELAELEEELEE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2168 LEEQLEQFREELENKNDEVQELLMQLEIQRKE-----------STTRLQELQQENRLFKVIEEQKEQIQDLETQIERLMS 2236
Cdd:COG1196    335 LEEELEELEEELEEAEEELEEAEAELAEAEEAlleaeaelaeaEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE 414

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770159 2237 EREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQREGARTLPEDEESFKHQLDKVTAEKLVLEQQVE 2302
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1897-2261 8.09e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.01  E-value: 8.09e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1897 QIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEAGPVEQQFLQETEKLMKEKLEVQcQAEKVR 1976
Cdd:TIGR02168  671 SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE-QLEERI 749

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1977 GDLQKQVKALEIDVEEQVSRFIELEQEKNA---ELTDLRQQSQALEKQLEKMRKFLDE-QAIDREHERDVFQQEiqkleh 2052
Cdd:TIGR02168  750 AQLSKELTELEAEIEELEERLEEAEEELAEaeaEIEELEAQIEQLKEELKALREALDElRAELTLLNEEAANLR------ 823

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2053 qlkavpriqpvsehqaREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQALlasaepfPKVED 2132
Cdd:TIGR02168  824 ----------------ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL-------EALLN 880

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2133 QKRsgaveadpelSLEVQLQVERDATDRKQKEITNLEEQLEQFREELENKNDEVQEL---LMQLEIQRKESTTRLQELQQ 2209
Cdd:TIGR02168  881 ERA----------SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLelrLEGLEVRIDNLQERLSEEYS 950

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039770159 2210 ---------ENRLFKVIEEQKEQIQDLETQIERL-------MSEREHEKKQREE---EVEQLTGVVEKLQQ 2261
Cdd:TIGR02168  951 ltleeaealENKIEDDEEEARRRLKRLENKIKELgpvnlaaIEEYEELKERYDFltaQKEDLTEAKETLEE 1021
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 192-860 1.14e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 1.14e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  192 IITQLTANLQQARREKDDTMvEFLELTEQSQKLQIQ-----FQHLQANETLQNSTLSRTATDLLQAKRQIFTQQQQLQDY 266
Cdd:COG1196    194 ILGELERQLEPLERQAEKAE-RYRELKEELKELEAEllllkLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  267 QKKEEDLQAQISFLQEKLRAFEMEKDR--KIENLNAKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQ 344
Cdd:COG1196    273 RLELEELELELEEAQAEEYELLAELARleQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  345 LTQRNQEIQSLKLELGNSQQNERKCSEEIKELMRTVEELQKRNLKDSWLETSAVRRVEQETQRKLSHLQAELDEMYGKQI 424
Cdd:COG1196    353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  425 VQMKQELINQHMSQIEELKSQHKREMENTLKSDTNAAISKEQV-NLMNAAINELNVRLQETHAQKEELKGELGVVLGEKS 503
Cdd:COG1196    433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLeAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  504 ALQSQSNDLLEEVRFLREQVQKARQTIAEQENRLSEARKSLSTVEDLKAEIVAASESRkelelkheaeitnykiklemLE 583
Cdd:COG1196    513 ALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAK--------------------AG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  584 KEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEVEHRINIEKLKDNLgihykqqiDGLQNEMNRKMESMQCE 663
Cdd:COG1196    573 RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL--------VAARLEAALRRAVTLAG 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  664 TDNLITQQNQLILENSKLRDLQEclvNSKSEEMNLQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKED 743
Cdd:COG1196    645 RLREVTLEGEGGSAGGSLTGGSR---RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  744 DLQEKCAQLDAENNILKEEkrvLEDKLKMYSPSEQEERSIAVDPSTsksadsrWQKEVAMLRKETEDLQqqclylneeie 823
Cdd:COG1196    722 EEEALEEQLEAEREELLEE---LLEEEELLEEEALEELPEPPDLEE-------LERELERLEREIEALG----------- 780

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|...
gi 1039770159  824 kqrntfafaeknfEVN------YQELQREYTCLLKIRDDLEAT 860
Cdd:COG1196    781 -------------PVNllaieeYEELEERYDFLSEQREDLEEA 810
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1809-2270 1.89e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.74  E-value: 1.89e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1809 RLQAAVEKLLEAISETNTQLEHAKVTQTELMRESFRQKQEATESLHCLEELRERLQEESRAREQLAEELNKAESVIDGYS 1888
Cdd:COG1196    285 EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1889 DEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEAGPVEQQfLQETEKLMKEKLEV 1968
Cdd:COG1196    365 EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEA-LAELEEEEEEEEEA 443

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1969 QCQAEKVRGDLQKQVKALEIDVEEQVSRFIELEQEKNAELTDLRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQ 2048
Cdd:COG1196    444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2049 KLEHQLKAVP-------------RIQPVSEHQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRE 2115
Cdd:COG1196    524 GAVAVLIGVEaayeaaleaalaaALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDL 603

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2116 LEQALLASAEPFPKVEDQKRSGAVEADPELSLEVQLQVERDATDRKQKEITNLEE----------QLEQFREELENKNDE 2185
Cdd:COG1196    604 VASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAggsltggsrrELLAALLEAEAELEE 683

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2186 VQELLMQLEIQRKESTTRLQELQQENRLFKVIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEVVS 2265
Cdd:COG1196    684 LAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE 763


                   ....*
gi 1039770159 2266 TEQQR 2270
Cdd:COG1196    764 ELERE 768
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 344-755 5.04e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.32  E-value: 5.04e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  344 QLTQRNQEIQSLKLELGNSQQNERKCSEEIKELMRTVEELQKrnlkdswlETSAVRRVEQETQRKLSHLQAELDEMygKQ 423
Cdd:TIGR02168  671 SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEE--------ELEQLRKELEELSRQISALRKDLARL--EA 740

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  424 IVQMKQELINQHMSQIEELksqhkrementlksdtnaaisKEQVNLMNAAINELNVRLQETHAQKEELKGELGVVLGEKS 503
Cdd:TIGR02168  741 EVEQLEERIAQLSKELTEL---------------------EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELK 799

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  504 ALQSQSNDLLEEVRFLREQVQKARQTIAEQENRLSEARKSLstvEDLKAEIVAASESRKELelkhEAEITNYKIKLEMLE 583
Cdd:TIGR02168  800 ALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL---EDLEEQIEELSEDIESL----AAEIEELEELIEELE 872

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  584 KEKNAVLDRMAESQEAelerlrtqlLFSHEEELSKLKEDLEvEHRINIEKLKDNLgihykQQIDGLQNEMNRKMESMQCE 663
Cdd:TIGR02168  873 SELEALLNERASLEEA---------LALLRSELEELSEELR-ELESKRSELRREL-----EELREKLAQLELRLEGLEVR 937

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  664 TDNLITQQnqlileNSKLRDLQEcLVNSKSEEMNLQINELQKEIEILKQEEKEKG----TLEQEVQELQLKTEQLEKQ-- 737
Cdd:TIGR02168  938 IDNLQERL------SEEYSLTLE-EAEALENKIEDDEEEARRRLKRLENKIKELGpvnlAAIEEYEELKERYDFLTAQke 1010

                          410
                   ....*....|....*....
gi 1039770159  738 -LKEKEDDLQEKCAQLDAE 755
Cdd:TIGR02168 1011 dLTEAKETLEEAIEEIDRE 1029
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1868-2457 1.11e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 68.17  E-value: 1.11e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1868 RAREQLAEELNKAESV---IDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERqllcRQREAMR 1944
Cdd:PRK03918   176 RRIERLEKFIKRTENIeelIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELE----KELESLE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1945 AEAGPVEQQfLQETEKLMKEKLEVQCQAEKVRGDLQK-QVKALE-IDVEEQVSRFIELEQEKNAELTDLRQQSQALEKQL 2022
Cdd:PRK03918   252 GSKRKLEEK-IRELEERIEELKKEIEELEEKVKELKElKEKAEEyIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERI 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2023 EKMRKfLDEQAIDREHERDVFQQEIQKLEHQLKAVPRIQPVSEHQAREVEQLTNHLKEKTDRCSELL-LSKEQLQRDIQE 2101
Cdd:PRK03918   331 KELEE-KEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELeKAKEEIEEEISK 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2102 RNEEIEKLECRVRELEQALLASAEPFPKVEDQKRSGAVEADPELSLEVQLQVERdaTDRKQKEITNLEEQLEQFREELEN 2181
Cdd:PRK03918   410 ITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKR--IEKELKEIEEKERKLRKELRELEK 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2182 KNDEVQELLMQL-------EIQRKESTTRLQELQQENRLFkviEEQKEQIQDLETQIERLMSE--REHEKKQREEEVEQL 2252
Cdd:PRK03918   488 VLKKESELIKLKelaeqlkELEEKLKKYNLEELEKKAEEY---EKLKEKLIKLKGEIKSLKKEleKLEELKKKLAELEKK 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2253 TGVVEKLQQEVVsTEQQREGARTLPEDEESFKhQLDKVTAEKLVL---EQQVETTnqvmthmnnvLKEINFKMDQITQSL 2329
Cdd:PRK03918   565 LDELEEELAELL-KELEELGFESVEELEERLK-ELEPFYNEYLELkdaEKELERE----------EKELKKLEEELDKAF 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2330 CNLNKECASNEELPSlpkesvhmTVHELGSDNLQPEDAPAQDVTKPLEKQTSLTRLQKSPEASRTQEIESLASSVGAKDV 2409
Cdd:PRK03918   633 EELAETEKRLEELRK--------ELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELE 704

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1039770159 2410 ELTQCREQTETIqEQAQSETDRLQKKLTDLQRSLEKFAAALVSQVQME 2457
Cdd:PRK03918   705 EREKAKKELEKL-EKALERVEELREKVKKYKALLKERALSKVGEIASE 751
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
437-974 1.17e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.78  E-value: 1.17e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  437 SQIEELKSQHKREMENTLKSdtnaaiskeqvnlmnaaINELNVRLQETHAQKEEL---KGELGVVLGEKSALQSQSNDLL 513
Cdd:PRK03918   189 ENIEELIKEKEKELEEVLRE-----------------INEISSELPELREELEKLekeVKELEELKEEIEELEKELESLE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  514 EEVRFLREQVQKARQTIAEQENRLSEARKSLSTVEDLKAEIVAASESRKELElKHEAEITNYKIKLEMLEKEKNAVLDRM 593
Cdd:PRK03918   252 GSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYE-EYLDELREIEKRLSRLEEEINGIEERI 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  594 --AESQEAELERLRtQLLFSHEEELSKLKEDLEVEHRI-----NIEKLKDNLGIHYKQQIDGLQNEMNRKMESMQCETDN 666
Cdd:PRK03918   331 keLEEKEERLEELK-KKLKELEKRLEELEERHELYEEAkakkeELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISK 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  667 LITQQNQLILENSKLRDLQECLVNSKSE--EMNLQINELQKEiEILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEDD 744
Cdd:PRK03918   410 ITARIGELKKEIKELKKAIEELKKAKGKcpVCGRELTEEHRK-ELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKV 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  745 LqEKCAQLDAENNILkEEKRVLEDKLKMYSPSEQEERSIAVDPSTSKSADSRWQ--------KEVAMLRKETEDLQQQCL 816
Cdd:PRK03918   489 L-KKESELIKLKELA-EQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEikslkkelEKLEELKKKLAELEKKLD 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  817 YLNEE---IEKQRNTFAF-AEKNFEVNYQELQ---REYTCLLKIRDDLEATQTKQALEyESKLRALEEELlskrgnpaap 889
Cdd:PRK03918   567 ELEEElaeLLKELEELGFeSVEELEERLKELEpfyNEYLELKDAEKELEREEKELKKL-EEELDKAFEEL---------- 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  890 kGKSSGIFPSETLEIGEVVEKDTTELMEKLEvtkREKLELSEKVSGLSEQLKQTHCTINSLSAEVRALKQEKEQLLLRCG 969
Cdd:PRK03918   636 -AETEKRLEELRKELEELEKKYSEEEYEELR---EEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKK 711


                   ....*
gi 1039770159  970 ELELL 974
Cdd:PRK03918   712 ELEKL 716
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1797-2292 1.24e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.78  E-value: 1.24e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1797 PENEELMLNISSRLQAaVEKLLEAISETNTQLE---------HAKVTQTELMRESFRQKQEATES----LHCLEELRERL 1863
Cdd:PRK03918   217 PELREELEKLEKEVKE-LEELKEEIEELEKELEslegskrklEEKIRELEERIEELKKEIEELEEkvkeLKELKEKAEEY 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1864 QEESRAREQLAEELNKAESVIDGYSDEKTLFERQIQE---KTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQR 1940
Cdd:PRK03918   296 IKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEleeKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELE 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1941 EAMRAEAGPVEQQFLQETEKLMKEKLEVQCQAEKV---RGDLQKQVKALEIDVEEQVS---------RFIELEQEKN--- 2005
Cdd:PRK03918   376 RLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKItarIGELKKEIKELKKAIEELKKakgkcpvcgRELTEEHRKElle 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2006 ---AELTDLRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEiqKLEHQLKAVPriQPVSEHQAREVEQLTnhlkEKT 2082
Cdd:PRK03918   456 eytAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLK--ELAEQLKELE--EKLKKYNLEELEKKA----EEY 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2083 DRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQALLASAEPFPKVEDQKRSGAVEADPELSLEVQ-----------L 2151
Cdd:PRK03918   528 EKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKelepfyneyleL 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2152 QVERDATDRKQKEITNLEEQLEQFREELENKNDEVQELlmqleiqrkesTTRLQELQQenrlfKVIEEQKEQIQDLETQI 2231
Cdd:PRK03918   608 KDAEKELEREEKELKKLEEELDKAFEELAETEKRLEEL-----------RKELEELEK-----KYSEEEYEELREEYLEL 671

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039770159 2232 ERLMSEREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQREgartlpeDEESFKHQLDKVTA 2292
Cdd:PRK03918   672 SRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKK-------ELEKLEKALERVEE 725
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 152-525 1.46e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 1.46e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  152 EKQHDIEELTQELEEMRAsfgteglkQLQEFEAAIKQRDGIITQLTANLQQARREKDDTMVEFLELTEQSQKLQIQFQHL 231
Cdd:TIGR02168  674 ERRREIEELEEKIEELEE--------KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  232 QANETLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEmekdrkienlnaKEIQEKQALID 311
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR------------EALDELRAELT 813

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  312 ELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEIKELM--RTVEELQKRNLK 389
Cdd:TIGR02168  814 LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLneRASLEEALALLR 893

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  390 DSWLETSAVRRVEQETQRKLSHLQAELDEMYGkQIVQMKQELINQHMSQIEELKSQHKREME----NTLKSDTNAAISKE 465
Cdd:TIGR02168  894 SELEELSEELRELESKRSELRRELEELREKLA-QLELRLEGLEVRIDNLQERLSEEYSLTLEeaeaLENKIEDDEEEARR 972

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039770159  466 QVNLMNAAINEL-NVRLqETHAQKEELKgelgvvlGEKSALQSQSNDLLEEVRFLREQVQK 525
Cdd:TIGR02168  973 RLKRLENKIKELgPVNL-AAIEEYEELK-------ERYDFLTAQKEDLTEAKETLEEAIEE 1025
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2966-3301 1.73e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.73e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2966 EMQLELSSLRDRAAELQEQLSS--------EKmvVAELKSELAQAKLELG-----------TTLKAQHKRLK-ELEAFRS 3025
Cdd:COG1196    183 ATEENLERLEDILGELERQLEPlerqaekaER--YRELKEELKELEAELLllklreleaelEELEAELEELEaELEELEA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3026 EVKEKTDEIHFLSDTLAREQKNSLELQWALEKEKARSGHHEGREKEELEDLKFSLEDQKRRNTQLNLLLEQQKQLLNESQ 3105
Cdd:COG1196    261 ELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELE 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3106 QKIESQKMLHDAQLSEEQGRNLGLQALLESEQVRIQEMKSTLDKERELYAQLQSREDggqpppalpsedlLKELQKQLEE 3185
Cdd:COG1196    341 ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE-------------LAAQLEELEE 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3186 KHSRIVELLSETEKYKLDSLQTRQQMEKDRQVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQQVYKLDLEGK 3265
Cdd:COG1196    408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELA 487

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 1039770159 3266 RLQGLMQEFQKQELEPEEKPGSRGLVDQNLNEPATW 3301
Cdd:COG1196    488 EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1862-2245 1.85e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.39  E-value: 1.85e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1862 RlqeesraREQLAEELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQRE 1941
Cdd:TIGR02168  685 K-------IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1942 AMRAEAGPVEQQFLQETEKLMkeklevqcQAEKVRGDLQKQVKALEIDVEEQVSRFIELEQEKNAELTDLRQQSQALEkQ 2021
Cdd:TIGR02168  758 ELEAEIEELEERLEEAEEELA--------EAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLE-S 828

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2022 LEKMRKFLDEQAIDREHERDVFQQEIQKLEHQLkavpriqpvsEHQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQE 2101
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIEELSEDIESLAAEI----------EELEELIEELESELEALLNERASLEEALALLRSELEE 898

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2102 RNEEIEKLECRVRELEQALLASAEPFPKVEDQKRSGAVEADPELS-LEVQLQVERDATDRKQKEITNLEEQLEQFREELE 2180
Cdd:TIGR02168  899 LSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQErLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLE 978

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039770159 2181 NKNDEVQELLMqleiqrkestTRLQELQQENRLFKVIEEQKEQIQDLETQIERLMSEREHEKKQR 2245
Cdd:TIGR02168  979 NKIKELGPVNL----------AAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARER 1033
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1838-2212 2.18e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.02  E-value: 2.18e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1838 LMRESFRQKQEATESLHCLEELRERLQEESRAREQLAEELNKAesvidgysdektlferqiqektdiiehleqevlcmNN 1917
Cdd:TIGR02169  693 LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKL-----------------------------------KE 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1918 RLQELESDQRRVEEERQLLCRQREAMRAEAGPVEQQFLQETEKLmkEKLEVQCQAEKVRgDLQKQVKALEIDVEEQVSRF 1997
Cdd:TIGR02169  738 RLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEAL--NDLEARLSHSRIP-EIQAELSKLEEEVSRIEARL 814

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1998 IELEQEKNAEltdlrqqsQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEHQLKAVPRIqpVSEHQArEVEQLTNH 2077
Cdd:TIGR02169  815 REIEQKLNRL--------TLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEE--LEELEA-ALRDLESR 883

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2078 LKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQALLASAEPFPKVEDQKRSGAVEADPELSLEvQLQVERda 2157
Cdd:TIGR02169  884 LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLE-DVQAEL-- 960

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039770159 2158 tDRKQKEITNLEE---QLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENR 2212
Cdd:TIGR02169  961 -QRVEEEIRALEPvnmLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKR 1017
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2008-2342 2.38e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.00  E-value: 2.38e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2008 LTDLRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEhqlkavpriqpvsehqaREVEQLTNHLKEKTDRCSE 2087
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELR-----------------EELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2088 LLLSKEQLQRDIQERNEEIEKLECRVRELEQALLASAEpfpKVEDqkrsgaveadpelsLEVQLQVERDATDRKQKEITN 2167
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN---EISR--------------LEQQKQILRERLANLERQLEE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2168 LEEQLEQfreeLENKNDEVQELLMQLEIQRKESTTRLQELQQE-NRLFKVIEEQKEQIQDLETQIERLMSER---EHEKK 2243
Cdd:TIGR02168  321 LEAQLEE----LESKLDELAEELAELEEKLEELKEELESLEAElEELEAELEELESRLEELEEQLETLRSKVaqlELQIA 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2244 QREEEVEQLTGVVEKLQQEVVSTEQQREGARTLPEDEESFKHQ--LDKVTAEKLVLEQQVETTNQVMTHMNNVLKEINFK 2321
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQaeLEELEEELEELQEELERLEEALEELREELEEAEQA 476

                          330       340
                   ....*....|....*....|.
gi 1039770159 2322 MDQITQSLCNLNKECASNEEL 2342
Cdd:TIGR02168  477 LDAAERELAQLQARLDSLERL 497
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 139-845 3.03e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 66.92  E-value: 3.03e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  139 SQTCLQMVEKELAEKQHDIEELTQELEEMRASFGTEGLKQLQEFEAAIKQRDGIITQLTANLQQARREKDDTMVEFLELT 218
Cdd:pfam02463  319 SEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE 398

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  219 EQSQKLQIQFQHLQANETLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEMEKDRKIENL 298
Cdd:pfam02463  399 LKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ 478

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  299 NAKEI--QEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNsqQNERKCSEEIKEL 376
Cdd:pfam02463  479 LVKLQeqLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKV--AISTAVIVEVSAT 556

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  377 MRTVEELQKRNLKDSWLETSAVRRVEQETQRKLSHLQAELDEMYGKQIVQMKQELINQHMSQIEELKSQHKREMENTLKS 456
Cdd:pfam02463  557 ADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTK 636

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  457 DTNAAISKEQVNLMNAAINELNVRLQETHAQKEELKGELGVVLgEKSALQSQSNDLLEEVRFLREQVQKARQTIAEQENR 536
Cdd:pfam02463  637 LKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQ-ELQEKAESELAKEEILRRQLEIKKKEQREKEELKKL 715

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  537 LSEARKSL----STVEDLKAEIVAASESRKELELKHEAEITNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSH 612
Cdd:pfam02463  716 KLEAEELLadrvQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEK 795

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  613 EEELSKLKEDLEVEHRINIEKLK-DNLGIHYKQQIDGLQNEMNRKMESMQCETDNLITQQNQLILENSKLRDLqeclvNS 691
Cdd:pfam02463  796 LKAQEEELRALEEELKEEAELLEeEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEEL-----LQ 870

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  692 KSEEMNLQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAENNILKEEKRVLEDKLK 771
Cdd:pfam02463  871 ELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEK 950

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039770159  772 MYSPSEQEERSIAVDPSTSKSAdsrwQKEVAMLRKETEDLQQQclYLNEEIEKQRNTFAFAEKNFEVNYQELQR 845
Cdd:pfam02463  951 EENNKEEEEERNKRLLLAKEEL----GKVNLMAIEEFEEKEER--YNKDELEKERLEEEKKKLIRAIIEETCQR 1018
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 255-771 3.66e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 66.20  E-value: 3.66e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  255 QIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEMEKDRK---IENLNAKEIQEKQAL--IDELNTRVVEEEKKTVELKN 329
Cdd:TIGR04523  146 EIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIqknIDKIKNKLLKLELLLsnLKKKIQKNKSLESQISELKK 225

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  330 KVTTadellggLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEIKELmrtveelqKRNLKDSWLETSAVRRVEQETQRKL 409
Cdd:TIGR04523  226 QNNQ-------LKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKI--------KKQLSEKQKELEQNNKKIKELEKQL 290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  410 SHLQAELDEMYGkqivQMKQELINQHMSQIEELKSQhKREMENTLkSDTNAAIS--KEQVNLMNAAINELNVRLQETHAQ 487
Cdd:TIGR04523  291 NQLKSEISDLNN----QKEQDWNKELKSELKNQEKK-LEEIQNQI-SQNNKIISqlNEQISQLKKELTNSESENSEKQRE 364

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  488 KEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKARQTIAEQENRLSEARKSLSTVE----DLKAEIVAASESRKE 563
Cdd:TIGR04523  365 LEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEkeieRLKETIIKNNSEIKD 444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  564 LElkheAEITNYKIKLEMLEKEKnavldrmaESQEAELERLrtqllfshEEELSKLKEDLEVEHRINIEKLKDNLGI-HY 642
Cdd:TIGR04523  445 LT----NQDSVKELIIKNLDNTR--------ESLETQLKVL--------SRSINKIKQNLEQKQKELKSKEKELKKLnEE 504

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  643 KQQIDGLQNEMNRKMESMQCETDNLITQQNQLILENSKLRD-LQECLVNSKSEEMNLQINELQKEIEILKQEEKEKGTLE 721
Cdd:TIGR04523  505 KKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDeLNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQ 584

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039770159  722 QEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAENNILKEEKRVLEDKLK 771
Cdd:TIGR04523  585 EEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIK 634
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 268-973 4.43e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 66.30  E-value: 4.43e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  268 KKEEDLQAQISFLQEKLRAFEMEKDrKIENLNAKEIQEKQALIDELNTRVVEEEK----KTVELKNKVTTADELLGGL-- 341
Cdd:pfam15921  103 KQKFYLRQSVIDLQTKLQEMQMERD-AMADIRRRESQSQEDLRNQLQNTVHELEAakclKEDMLEDSNTQIEQLRKMMls 181

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  342 HEQLTQrnqEIQSLKLELgnsqqnERKCSEEIKElMRTVEELQKRNLKdswletSAVRRVEQETQRKLSHLQAEL----D 417
Cdd:pfam15921  182 HEGVLQ---EIRSILVDF------EEASGKKIYE-HDSMSTMHFRSLG------SAISKILRELDTEISYLKGRIfpveD 245

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  418 EMYG-KQIVQMKQELI-NQHMSQIEELKSQHKREMENTLKSDTNA-----------AISKEQVNLMNA-----------A 473
Cdd:pfam15921  246 QLEAlKSESQNKIELLlQQHQDRIEQLISEHEVEITGLTEKASSArsqansiqsqlEIIQEQARNQNSmymrqlsdlesT 325

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  474 INELNVRLQET----HAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKARQTIAEQENRLSEARKSLSTVED 549
Cdd:pfam15921  326 VSQLRSELREAkrmyEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWD 405

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  550 LK-AEIVAASESRKELELKHeAEITNYKIKLEMLEKEKNAVLDRMAESQEAELERLR-----TQLLFSHEEELSKLKEDL 623
Cdd:pfam15921  406 RDtGNSITIDHLRRELDDRN-MEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEkvsslTAQLESTKEMLRKVVEEL 484

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  624 EVEhRINIEKLKDNLgihykQQIDGLQNEMNRKMESMQCETDNLITQQNQLILENSKLRDLQECLVNSKSE--EMNLQIN 701
Cdd:pfam15921  485 TAK-KMTLESSERTV-----SDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTEceALKLQMA 558

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  702 ELQKEIEILKQEEKEK----GTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAENNILKE-EKRVLE---DKLKMY 773
Cdd:pfam15921  559 EKDKVIEILRQQIENMtqlvGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRElEARVSDlelEKVKLV 638

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  774 SPSEQEERSIavdpstsksadsrwqkevamlrketEDLQQQCLYLNEEIEKQRNTFafaeKNFEVNYQELQREYTcllKI 853
Cdd:pfam15921  639 NAGSERLRAV-------------------------KDIKQERDQLLNEVKTSRNEL----NSLSEDYEVLKRNFR---NK 686

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  854 RDDLEATQTKQALEYESKLRALEEE---LLSKRGNPAAPKGKSSGIFPSETLEIGEV--VEKDTTELMEKLEVTKREKLE 928
Cdd:pfam15921  687 SEEMETTTNKLKMQLKSAQSELEQTrntLKSMEGSDGHAMKVAMGMQKQITAKRGQIdaLQSKIQFLEEAMTNANKEKHF 766

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*
gi 1039770159  929 LSEKVSGLSEQLKQTHCTINSLSAEVRALKQEKEQLLLRCGELEL 973
Cdd:pfam15921  767 LKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEV 811
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1871-2445 5.47e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 5.47e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1871 EQLAEELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEAGPV 1950
Cdd:TIGR02168  249 KEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEEL 328

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1951 EQQfLQETEKLMKEKLEVQCQAEKVRGDLQKQVKALEIDVEEQVSRFIELEQE---KNAELTDLRQQSQALEKQLEKMRK 2027
Cdd:TIGR02168  329 ESK-LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQletLRSKVAQLELQIASLNNEIERLEA 407

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2028 FLdeQAIDREHERDVFQQEIQKLEHQLKAVPRIQPVSEHQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIE 2107
Cdd:TIGR02168  408 RL--ERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2108 KLECRVRELEQ-------------ALLASAEPFPKVEDQKRSG-AVEADPELSLEVQLQ-------VERDATDR------ 2160
Cdd:TIGR02168  486 QLQARLDSLERlqenlegfsegvkALLKNQSGLSGILGVLSELiSVDEGYEAAIEAALGgrlqavvVENLNAAKkaiafl 565

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2161 KQKEIT-----------------NLEEQLEQFREELENKNDEVQE----------LLMQLEI-QRKESTTRLQ-ELQQEN 2211
Cdd:TIGR02168  566 KQNELGrvtflpldsikgteiqgNDREILKNIEGFLGVAKDLVKFdpklrkalsyLLGGVLVvDDLDNALELAkKLRPGY 645

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2212 RLF---------------------KVIEEQKEQIQDLETQIERlMSEREHEKKQR----EEEVEQLTGVVEKLQQEVVST 2266
Cdd:TIGR02168  646 RIVtldgdlvrpggvitggsaktnSSILERRREIEELEEKIEE-LEEKIAELEKAlaelRKELEELEEELEQLRKELEEL 724

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2267 EQQ----REGARTLPEDEESFKHQLDKVTAEKLVLEQQVETTNQVMTHMNNVLKEINFKMDQITQSLCNLNKECASNEEL 2342
Cdd:TIGR02168  725 SRQisalRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREA 804

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2343 pslpKESVHMTVHELGSDNLQPEDAPAQDVTKPLEKQTSLTRLQKSPEaSRTQEIESLASSVGAKDVELTQCREQTETIQ 2422
Cdd:TIGR02168  805 ----LDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE-ELSEDIESLAAEIEELEELIEELESELEALL 879

                          650       660
                   ....*....|....*....|....*.
gi 1039770159 2423 E---QAQSETDRLQKKLTDLQRSLEK 2445
Cdd:TIGR02168  880 NeraSLEEALALLRSELEELSEELRE 905
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 144-842 1.11e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 64.75  E-value: 1.11e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  144 QMVEKELAEKQHDIEELTQELEEmrasfgTEGLKQLQEFEAaikqRDGIItQLTANLQQARREKDdTMVEFLELTEQSQ- 222
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNE------SNELHEKQKFYL----RQSVI-DLQTKLQEMQMERD-AMADIRRRESQSQe 141

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  223 ----KLQIQFQHLQANETLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEMEKDRKIENL 298
Cdd:pfam15921  142 dlrnQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSA 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  299 NAKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLH----EQLTQRNQ-EIQSL--KLELGNSQQNERKCSE 371
Cdd:pfam15921  222 ISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHqdriEQLISEHEvEITGLteKASSARSQANSIQSQL 301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  372 E-IKELMRTVEELQKRNLKDSWLETSAVRRVEQETQRKLSHLQAELDemygKQIVQMKQEL---------INQHMSQIEE 441
Cdd:pfam15921  302 EiIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELE----KQLVLANSELtearterdqFSQESGNLDD 377

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  442 -----LKSQHKREMENTLKSDTNAAI------SKEQVNLMNAAINELNVRLQETHAQKEELKGELGVVLGEKSALQSQSN 510
Cdd:pfam15921  378 qlqklLADLHKREKELSLEKEQNKRLwdrdtgNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKN 457

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  511 DLLEEVRFLREQVQKARQTIAEQENRLSEARKSLS----TVEDLKAEI-------------VAASESRKELELKHEAEIT 573
Cdd:pfam15921  458 ESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLEsserTVSDLTASLqekeraieatnaeITKLRSRVDLKLQELQHLK 537

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  574 NYKIKLEMLEKEKNAVLDRMAESQEAeLERLR------TQLLFSHEEELSKLK-EDLEVEHRINIEKLKDNLGIHYKQQI 646
Cdd:pfam15921  538 NEGDHLRNVQTECEALKLQMAEKDKV-IEILRqqienmTQLVGQHGRTAGAMQvEKAQLEKEINDRRLELQEFKILKDKK 616

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  647 DGLQNEMNRKMESMQCETDNLITQQNQLILENSKLRDLQECLVNSKSEEMNlQINELQKEIEILKQEEKEKGtleqevQE 726
Cdd:pfam15921  617 DAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRN-ELNSLSEDYEVLKRNFRNKS------EE 689

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  727 LQLKTEQLEKQLKEKEDDLQE----------------------------KCAQLDAENNILKEEKRVLEDKLKMYSPSEQ 778
Cdd:pfam15921  690 METTTNKLKMQLKSAQSELEQtrntlksmegsdghamkvamgmqkqitaKRGQIDALQSKIQFLEEAMTNANKEKHFLKE 769

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039770159  779 EERSIAVDPSTSKSADSRWQKEVAMLRKETEDLQQQClyLNEEIEKQRNTFAFAEKNFEVNYQE 842
Cdd:pfam15921  770 EKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKV--ANMEVALDKASLQFAECQDIIQRQE 831
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1810-2263 1.15e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.57  E-value: 1.15e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1810 LQAAVEKLLEAISETNTQLEHAKVTQTELMRESFRQKQEATESLHCLEELRERLQEESRAREQLAEELNKAESVIDGYSD 1889
Cdd:COG1196    356 AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE 435

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1890 EKTLFERQIQEKTDIIEHLEQEVLcmnnRLQELESDQRRVEEERQLLCRQREAMRAEAGPVEQQFLQETEKLMKEKLEVQ 1969
Cdd:COG1196    436 EEEEEEEALEEAAEEEAELEEEEE----ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1970 CQAEKVRGDLQKQVKALEIDVEEQVSRFIEleqekNAELTDLRQQSQALEKQLEKMRKFLDEQAIdrehERDVFQQEIQK 2049
Cdd:COG1196    512 AALLLAGLRGLAGAVAVLIGVEAAYEAALE-----AALAAALQNIVVEDDEVAAAAIEYLKAAKA----GRATFLPLDKI 582

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2050 LEHQLKAVPRIQPVSEHQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQALLASAEpfpk 2129
Cdd:COG1196    583 RARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA---- 658

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2130 veDQKRSGAVEADPELSLEVQLQVERDATDRKQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQ 2209
Cdd:COG1196    659 --GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREE 736

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2210 ENRLF------------------KVIEEQKEQIQDLETQIERL-----MSEREHE---------KKQR---EEEVEQLTG 2254
Cdd:COG1196    737 LLEELleeeelleeealeelpepPDLEELERELERLEREIEALgpvnlLAIEEYEeleerydflSEQRedlEEARETLEE 816


                   ....*....
gi 1039770159 2255 VVEKLQQEV 2263
Cdd:COG1196    817 AIEEIDRET 825
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 181-972 1.37e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 64.61  E-value: 1.37e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  181 EFEAAIKQRDGIITQLTANLQQARREKDDTMVEFLELTEQSQKLQIQFQhlQANETLQNSTLSRTATDLLQAKRQIFTQQ 260
Cdd:pfam02463  159 EEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAK--KALEYYQLKEKLELEEEYLLYLDYLKLNE 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  261 QQLQDYQKKEEDLQAQISFLQEKLRAFEMEKDR--KIENLNAKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELL 338
Cdd:pfam02463  237 ERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQvlKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKL 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  339 gGLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEIKELMRTVEELQKRNLKDSwletsavrrVEQETQRKLSHLQAELDE 418
Cdd:pfam02463  317 -KESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKL---------EQLEEELLAKKKLESERL 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  419 MYGKQIVQMKQELINQhMSQIEELKSQHKREMENTLKSDTNAAISKEQVNLMNAAINELNVRLQETHAQKEELKGELGVV 498
Cdd:pfam02463  387 SSAAKLKEEELELKSE-EEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  499 LGEKSALQSQSNDLLEEVRFLREQVQKARQ---TIAEQENRLSEARKSLSTVEDLKAEIVAASESRKELELKHEAEITNY 575
Cdd:pfam02463  466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLeerSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  576 KIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSK--LKEDLEVEHRINIEKLKDNLGIHYKQQID------ 647
Cdd:pfam02463  546 STAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKlpLKSIAVLEIDPILNLAQLDKATLEADEDDkrakvv 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  648 GLQNEMNRKMESMQCETDNLITQQNQLILENSKLRDLQECLVNSKSEEMNLQINELQKEIEILKQEEKEKGTLEQEVQEL 727
Cdd:pfam02463  626 EGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKE 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  728 QLKTEQLEKQLKEKEDDLQEKC-AQLDAENNILKEEKRVLEDKLKMYSPSEQEERSIAVDPStsksadsrwQKEVAMLRK 806
Cdd:pfam02463  706 QREKEELKKLKLEAEELLADRVqEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKS---------ELSLKEKEL 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  807 ETEDLQQQCLYLNEEIEKQRNtfafaEKNFEVNYQELQREYTCLLKIRDDLEATQTKQALEYESKLRALEEELLSKRGNP 886
Cdd:pfam02463  777 AEEREKTEKLKVEEEKEEKLK-----AQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKL 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  887 AAPKGKSSGIFPSETLEIGEVVEKDTTELMEKLEVTKREKLELSEKVSGLSEQLKQTHCTINSLSAEVRALKQEKEQLLL 966
Cdd:pfam02463  852 AEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILL 931


                   ....*.
gi 1039770159  967 RCGELE 972
Cdd:pfam02463  932 KYEEEP 937
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1973-2302 2.03e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.93  E-value: 2.03e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1973 EKVRGDLQKqvkaleidVEEQVSRFIELEQEKnaeltdlRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEH 2052
Cdd:TIGR02169  173 EKALEELEE--------VEENIERLDLIIDEK-------RQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALER 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2053 QLKAVpriqpvsehqAREVEQLTNHLkektdrcselllskEQLQRDIQERNEEIEKLECRVRELEQALLASAEPfPKVED 2132
Cdd:TIGR02169  238 QKEAI----------ERQLASLEEEL--------------EKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE-EQLRV 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2133 QKRSGAVEADPEL---SLEVQLQVERDATDRKQK---EITNLEEQLEQFREELENKN---DEVQELLMQLEIQRKESTTR 2203
Cdd:TIGR02169  293 KEKIGELEAEIASlerSIAEKERELEDAEERLAKleaEIDKLLAEIEELEREIEEERkrrDKLTEEYAELKEELEDLRAE 372

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2204 LQELQQENRLFKV--------IEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQREGART 2275
Cdd:TIGR02169  373 LEEVDKEFAETRDelkdyrekLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK 452

                          330       340
                   ....*....|....*....|....*..
gi 1039770159 2276 LPEDEESFKHQLDKVTAEKLVLEQQVE 2302
Cdd:TIGR02169  453 QEWKLEQLAADLSKYEQELYDLKEEYD 479
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 403-1161 4.65e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.77  E-value: 4.65e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  403 QETQRKLSHLQAELdemYGKQIVQMKQELiNQHMSQIEELKSQHKREmentlksdtnaaisKEQVNLMNAAINELNVRLQ 482
Cdd:TIGR02168  216 KELKAELRELELAL---LVLRLEELREEL-EELQEELKEAEEELEEL--------------TAELQELEEKLEELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  483 ETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKARQTIAEQENRLSEARKSLSTVEDLKAEIvaasesrk 562
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEEL-------- 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  563 elelkhEAEITNYKIKLEMLEKEKNAVLDRMAEsQEAELERLRtQLLFSHEEELSKLKEDLEvEHRINIEKLKDNLGihy 642
Cdd:TIGR02168  350 ------KEELESLEAELEELEAELEELESRLEE-LEEQLETLR-SKVAQLELQIASLNNEIE-RLEARLERLEDRRE--- 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  643 kqqidglQNEMNRKMESMQCETDNLITQQNQLILENSKLRDLQECLvnsksEEMNLQINELQKEIEILKQEEKEkgtLEQ 722
Cdd:TIGR02168  418 -------RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEEL-----ERLEEALEELREELEEAEQALDA---AER 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  723 EVQELQLKTEQLEkQLKEKEDDLQEKCAQLDAENNILKEEKRVLEDKLKmyspseqeersiaVDPSTSKSADSRWQKEVA 802
Cdd:TIGR02168  483 ELAQLQARLDSLE-RLQENLEGFSEGVKALLKNQSGLSGILGVLSELIS-------------VDEGYEAAIEAALGGRLQ 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  803 MLRKETEDLQQQCLYLNEEIEKQRNTF----AFAEKNFEVNYQELQREYTCLLKIRDDLEATQTK--------------- 863
Cdd:TIGR02168  549 AVVVENLNAAKKAIAFLKQNELGRVTFlpldSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllggvlvv 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  864 ----QALEYESKLRA------LEEELLSKRG--NPAAPKGKSSGIFPS-------ETLEIGE-----------VVEKDTT 913
Cdd:TIGR02168  629 ddldNALELAKKLRPgyrivtLDGDLVRPGGviTGGSAKTNSSILERRreieeleEKIEELEekiaelekalaELRKELE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  914 ELMEKLEVTKREKLELSEKVSGLSEQLKQTHCTINSLSAEVRALKQEKEQLLLRCGELELLANPSgTENAAVCPVQMSSY 993
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA-EEELAEAEAEIEEL 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  994 QAglvmgKVGDSGGSISKISKDLAEESKPMIEDKIPF-KESGREQLLLPTRAQKPSHATVEPCESEKLQQELHALKAEQD 1072
Cdd:TIGR02168  788 EA-----QIEQLKEELKALREALDELRAELTLLNEEAaNLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1073 DLRLQMEAQRICLfvvysTHADQVRAHME---KEREEALCSLKDELISAQQKKIDELHKMHQCQLQNFKIQETGDEpLQV 1149
Cdd:TIGR02168  863 ELEELIEELESEL-----EALLNERASLEealALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG-LEV 936

                          810
                   ....*....|..
gi 1039770159 1150 LIERLQQAVSEK 1161
Cdd:TIGR02168  937 RIDNLQERLSEE 948
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 121-624 6.79e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.26  E-value: 6.79e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  121 REEEFSLDDSSSEQGAQSSQTCLQMVEKELAEKQHDIEELTQELEEMRAsfgtEGLKQLQEFEAAIKQRDGIITQLtANL 200
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEE----ELEEAEEELEEAEAELAEAEEAL-LEA 370

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  201 QQARREKDDTMVEFLELTEQSQKLQIQFQHLQANETLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFL 280
Cdd:COG1196    371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  281 QEKLRAFEMEKDRKIENLNAKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELg 360
Cdd:COG1196    451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVL- 529

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  361 nsqqneRKCSEEIKELMRTVEE--LQKRNLKDswlETSAVRRVEQETQRKLSHLQAE-LDEMYGKQIVQMKQELINQHMS 437
Cdd:COG1196    530 ------IGVEAAYEAALEAALAaaLQNIVVED---DEVAAAAIEYLKAAKAGRATFLpLDKIRARAALAAALARGAIGAA 600

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  438 QIEELKSQHKREMENTLKSDTNAAISKEQVNLMNAainelNVRLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVR 517
Cdd:COG1196    601 VDLVASDLREADARYYVLGDTLLGRTLVAARLEAA-----LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALL 675

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  518 FLREQVQKARQTIAEQENRLSEARKSLSTVEDLKAEIVAASESRKELELKHEAEITNYKIKLEMLEKEKNAVLDRMAESQ 597
Cdd:COG1196    676 EAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE 755

                          490       500
                   ....*....|....*....|....*..
gi 1039770159  598 EAELERLRTQllfshEEELSKLKEDLE 624
Cdd:COG1196    756 LPEPPDLEEL-----ERELERLEREIE 777
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1899-2226 6.97e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.38  E-value: 6.97e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1899 QEKTDIIEHLEQEVLCmnNRLQELESDQRRVEEERQLLCRQREAMRAEAGPVEQQFlqetEKLMKEKLEVQCQAEKVRGD 1978
Cdd:TIGR02168  216 KELKAELRELELALLV--LRLEELREELEELQEELKEAEEELEELTAELQELEEKL----EELRLEVSELEEEIEELQKE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1979 LQKQVKALEiDVEEQVsrfieleQEKNAELTDLRQQSQALEKQLEKMRKFLDEQAID---REHERDVFQQEIQKLEHQLK 2055
Cdd:TIGR02168  290 LYALANEIS-RLEQQK-------QILRERLANLERQLEELEAQLEELESKLDELAEElaeLEEKLEELKEELESLEAELE 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2056 AVPRIQPVSEHQAREVEQLTNHLKEKTDrcsELLLSKEQLQRDIQERNEEIEKLECRVRELEQALLASAEPFPKVEDQKR 2135
Cdd:TIGR02168  362 ELEAELEELESRLEELEEQLETLRSKVA---QLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKEL 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2136 SGAVEadpelslevqlqverdatdRKQKEITNLEEQLEQFREELEnkndEVQELLMQLEIQRKESTTRLQELQQENRLFK 2215
Cdd:TIGR02168  439 QAELE-------------------ELEEELEELQEELERLEEALE----ELREELEEAEQALDAAERELAQLQARLDSLE 495

                          330
                   ....*....|.
gi 1039770159 2216 VIEEQKEQIQD 2226
Cdd:TIGR02168  496 RLQENLEGFSE 506
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 325-824 7.13e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.96  E-value: 7.13e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  325 VELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEIKELMRTVEELQKR--NLKDSwletsavrrvE 402
Cdd:TIGR04523   22 VGYKNIANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQikDLNDK----------L 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  403 QETQRKLSHLQAELDEMygKQIVQMKQELINQHMSQIEELKSQHKREMENtlKSDTNAAISKEQVNLmnaaiNELNVRLQ 482
Cdd:TIGR04523   92 KKNKDKINKLNSDLSKI--NSEIKNDKEQKNKLEVELNKLEKQKKENKKN--IDKFLTEIKKKEKEL-----EKLNNKYN 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  483 ETHAQKEELKGELGVVLGEKS-------------------------------ALQSQSNDLLEEVRFLREQVQKARQTIA 531
Cdd:TIGR04523  163 DLKKQKEELENELNLLEKEKLniqknidkiknkllklelllsnlkkkiqknkSLESQISELKKQNNQLKDNIEKKQQEIN 242

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  532 EQENRLSEARKSLSTVEDLKAEIVAASEsRKELELKH--------EAEITNYKIKLEMLEKEKNAVLDRMA----ESQEA 599
Cdd:TIGR04523  243 EKTTEISNTQTQLNQLKDEQNKIKKQLS-EKQKELEQnnkkikelEKQLNQLKSEISDLNNQKEQDWNKELkselKNQEK 321

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  600 ELERLRTQLLFShEEELSKLKEDLEvehriNIEKLKDNLGIHyKQQIDGLQNEMNRKMESMQCETDNLITQQNQLILENS 679
Cdd:TIGR04523  322 KLEEIQNQISQN-NKIISQLNEQIS-----QLKKELTNSESE-NSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQIN 394

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  680 KLrdlqeclvNSKSEEMNLQINELQKEIEILkqeEKEKGTLEQEVQELQLKTEQLEKQLKekedDLQEKCAQLDAENNIL 759
Cdd:TIGR04523  395 DL--------ESKIQNQEKLNQQKDEQIKKL---QQEKELLEKEIERLKETIIKNNSEIK----DLTNQDSVKELIIKNL 459

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039770159  760 KEEKRVLEDKLKMYSPSEQEERSIAVDpsTSKSADSRwQKEVAMLRKETEDLQQQCLYLNEEIEK 824
Cdd:TIGR04523  460 DNTRESLETQLKVLSRSINKIKQNLEQ--KQKELKSK-EKELKKLNEEKKELEEKVKDLTKKISS 521
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2044-2360 7.82e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.01  E-value: 7.82e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2044 QQEIQKLEHQLKavpRIQPVSEHQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQALLAs 2123
Cdd:TIGR02169  680 RERLEGLKRELS---SLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEN- 755

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2124 aepfpkvedqkrsgaveadpelslevqlqvERDATDRKQKEITNLEEQLEQFREELEN--------KNDEVQELLMQLEI 2195
Cdd:TIGR02169  756 ------------------------------VKSELKELEARIEELEEDLHKLEEALNDlearlshsRIPEIQAELSKLEE 805

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2196 QRKESTTRLQELQQE-NRLFKVIEEQKEQIQDLETQIERLmserEHEKKQREEEVEQLTGVVEKLQQEVVSTEQQregAR 2274
Cdd:TIGR02169  806 EVSRIEARLREIEQKlNRLTLEKEYLEKEIQELQEQRIDL----KEQIKSIEKEIENLNGKKEELEEELEELEAA---LR 878

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2275 TLPEDEESFKHQLDKVTAEKLVLEQQVETTNQVMTHMNNVLKEINFKMDQITQSLCNLNKECASNEELPS--LPKESVHM 2352
Cdd:TIGR02169  879 DLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEeeLSLEDVQA 958


                   ....*...
gi 1039770159 2353 TVHELGSD 2360
Cdd:TIGR02169  959 ELQRVEEE 966
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 147-748 9.68e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.57  E-value: 9.68e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  147 EKELAEKQHDIEELTQELEEMRASFgTEGLKQLQEFEAAI---KQRDGIITQLTANLQQARREKDDTMVEFLELTEQSQK 223
Cdd:TIGR04523  151 EKELEKLNNKYNDLKKQKEELENEL-NLLEKEKLNIQKNIdkiKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQ 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  224 LQIQFQHLQANETLQNSTLSRTATDLLQA-------KRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEMEKDRKIE 296
Cdd:TIGR04523  230 LKDNIEKKQQEINEKTTEISNTQTQLNQLkdeqnkiKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWN 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  297 NLNAKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLH-------EQLTQRNQEIQSLKlelgnsQQNERKc 369
Cdd:TIGR04523  310 KELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSEsensekqRELEEKQNEIEKLK------KENQSY- 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  370 SEEIKELmrtveELQKRNLKdswLETSAVRRVEQETQRKLSHLQAELDEMyGKQIVQMKQELINQHmSQIEELKSQhKRE 449
Cdd:TIGR04523  383 KQEIKNL-----ESQINDLE---SKIQNQEKLNQQKDEQIKKLQQEKELL-EKEIERLKETIIKNN-SEIKDLTNQ-DSV 451

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  450 MENTLKS-DTNAAISKEQVNLMNAAINELNVRLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKARQ 528
Cdd:TIGR04523  452 KELIIKNlDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLES 531

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  529 TIAEQENRLSEARKSLSTVED------LKAEIvaaSESRKELE-LKHE-----AEITNYKIKLEMLEKEKNAVLDRMAEs 596
Cdd:TIGR04523  532 EKKEKESKISDLEDELNKDDFelkkenLEKEI---DEKNKEIEeLKQTqkslkKKQEEKQELIDQKEKEKKDLIKEIEE- 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  597 qeaelerlRTQLLFSHEEELSKLKEDLE--VEHRINIEKLKDNLgihyKQQIDGLQNEMNRKMESmqceTDNLITQQNQL 674
Cdd:TIGR04523  608 --------KEKKISSLEKELEKAKKENEklSSIIKNIKSKKNKL----KQEVKQIKETIKEIRNK----WPEIIKKIKES 671

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039770159  675 ILENSKLRDLQECLVNSKSEEMNLQINELQKEIEILKQEEKEKgtleqEVQELQLKTEQLEKQLKEKEDDLQEK 748
Cdd:TIGR04523  672 KTKIDDIIELMKDWLKELSLHYKKYITRMIRIKDLPKLEEKYK-----EIEKELKKLDEFSKELENIIKNFNKK 740
PTZ00121 PTZ00121
MAEBL; Provisional
 2943-3280 1.25e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.70  E-value: 1.25e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2943 REQGTEKSSQELLDCSMQQKQSLEMQLELSSLRDRAAELQEQlSSEKMVVAELKSELAQAKLELGTTLKAQHKRLKELEA 3022
Cdd:PTZ00121  1437 KKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKK-AEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEA 1515

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3023 FRSEVKEKTDEIHflsdtLAREQKNSLELQWALEKEKARsghhegrEKEELEDLKFSLEDQKRRNTQLNLLLEQQKQLLN 3102
Cdd:PTZ00121  1516 KKAEEAKKADEAK-----KAEEAKKADEAKKAEEKKKAD-------ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKA 1583

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3103 ESQQKIESQKMLHDAQLSEEQGRNLGLQALLESEQVRIQEMKSTLDKERELYAQLQSREdggqpppalpSEDLLK--ELQ 3180
Cdd:PTZ00121  1584 EEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKE----------AEEKKKaeELK 1653

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3181 KQLEEKHSRIVELLSETEKYKLDSLQTRQQMEKDRQVHQKTLQTEQEANT--QGQKKMQELQSKVEELQRQLQEKRQQVY 3258
Cdd:PTZ00121  1654 KAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKaeELKKKEAEEKKKAEELKKAEEENKIKAE 1733

                          330       340
                   ....*....|....*....|..
gi 1039770159 3259 KLDLEGKRLQGLMQEFQKQELE 3280
Cdd:PTZ00121  1734 EAKKEAEEDKKKAEEAKKDEEE 1755
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2907-3226 1.58e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 1.58e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2907 EYHTAMDCLQKADRRSLLAEIEDLRAQINGGKMTLEREQGTEKSSQELLDcsMQQKQSLEMQLELSSLRDRAAELQEQLS 2986
Cdd:COG1196    214 RYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELA--ELEAELEELRLELEELELELEEAQAEEY 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2987 SEKMVVAELKSELAQAKLELGTTLKAQHKRLKELEAFRSEVKEKTDEIHFLSDTLAREQKNSLELQWALEKEKARsghhE 3066
Cdd:COG1196    292 ELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA----L 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3067 GREKEELEDLKFSLEDQKRRNTQLNLLLEQQKQLLNESQQKIESQKMLHDAQLSEEQGRNLGLQALLESEQVRIQEMKST 3146
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3147 LDKERELYAQLQSREdggqpppaLPSEDLLKELQKQLEEKHSRIVELLSETEKYKLDSLQTRQQMEKDRQVHQKTLQTEQ 3226
Cdd:COG1196    448 AEEEAELEEEEEALL--------ELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGL 519
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
282-879 1.62e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.85  E-value: 1.62e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  282 EKLRAFEMEKDRKIENlNAKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADEL---LGGLHEQLTQRNQEIQSLKLE 358
Cdd:PRK03918   182 EKFIKRTENIEELIKE-KEKELEEVLREINEISSELPELREELEKLEKEVKELEELkeeIEELEKELESLEGSKRKLEEK 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  359 LGNSQQNERKCSEEIKELMRTVEELQKrnLKDSWLETSAVRRVEQETQRKLSHLQAELDEMYGK-QIVQMKQELINQHMS 437
Cdd:PRK03918   261 IRELEERIEELKKEIEELEEKVKELKE--LKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEiNGIEERIKELEEKEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  438 QIEELKSQhKREMENTLksdtnaAISKEQVNLMNaainelnvRLQETHAQKEELKGELGVVLGEKSalqsqsNDLLEEVR 517
Cdd:PRK03918   339 RLEELKKK-LKELEKRL------EELEERHELYE--------EAKAKKEELERLKKRLTGLTPEKL------EKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  518 FLREQVQKARQTIAEQENRLSEARKSLST-VEDLKAEIVAASESRKELELKHEAEITN-YKIKLEMLEKEKnAVLDRMAE 595
Cdd:PRK03918   398 KAKEEIEEEISKITARIGELKKEIKELKKaIEELKKAKGKCPVCGRELTEEHRKELLEeYTAELKRIEKEL-KEIEEKER 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  596 SQEAELERLRTQLlfSHEEELSKLKEDLEvehriNIEKLKDNLGIHYKQqidglqnEMNRKMEsmqcetdnlitqqnqli 675
Cdd:PRK03918   477 KLRKELRELEKVL--KKESELIKLKELAE-----QLKELEEKLKKYNLE-------ELEKKAE----------------- 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  676 lensklrdlqeclvnsKSEEMNLQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAE 755
Cdd:PRK03918   526 ----------------EYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEE 589

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  756 nniLKEEKRVLEDKLKMY-----SPSEQEERSIAVDPSTSKSADSR-----WQKEVAMLRKETEDLQQqcLYLNEEIEKQ 825
Cdd:PRK03918   590 ---LEERLKELEPFYNEYlelkdAEKELEREEKELKKLEEELDKAFeelaeTEKRLEELRKELEELEK--KYSEEEYEEL 664

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1039770159  826 RNtfafaeknfevNYQELQREYTCLLKIRDDLEatqtKQALEYESKLRALEEEL 879
Cdd:PRK03918   665 RE-----------EYLELSRELAGLRAELEELE----KRREEIKKTLEKLKEEL 703
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2875-3200 1.73e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.72  E-value: 1.73e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2875 LATFQTELTSLSTRDVDGLLNSLEQRIQEQgieyhtamdclqKADRRSLLAEIEDLRAQINGGKMTLEREQGTEKSSQEL 2954
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEEL------------EAELEELEAELAELEAELEELRLELEELELELEEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2955 LDCSMQQKQSLEMQLE-LSSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELGTTLKAQHKRLKELEAFRSEVKEKTDE 3033
Cdd:COG1196    290 EYELLAELARLEQDIArLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3034 IHFLSDTLAREQKNSLELQWALEKEKARSGHHEGREKEELEDLKFSLEDQKRRNTQLNLLLEQQKQLLNESQQKIESQKM 3113
Cdd:COG1196    370 AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3114 LHDAQLSEEQGRNLGLQALLESEQVRIQEMKSTLDKERELYAQLQSREDGGQPPPALPSEDLLKELQKQLEEKHSRIVEL 3193
Cdd:COG1196    450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVL 529


                   ....*..
gi 1039770159 3194 LSETEKY 3200
Cdd:COG1196    530 IGVEAAY 536
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1871-2348 2.70e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 60.03  E-value: 2.70e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1871 EQLAEELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNR-------LQELESDQRRVEEERQLLCRQREAM 1943
Cdd:TIGR04523   43 KTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKlkknkdkINKLNSDLSKINSEIKNDKEQKNKL 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1944 RAEAGPVEQQFLQETEKLMKEKLEV---QCQAEKVRGDLQKQVKALEiDVEEQVSRFIELEQEKNAELTDLRQQSQALEK 2020
Cdd:TIGR04523  123 EVELNKLEKQKKENKKNIDKFLTEIkkkEKELEKLNNKYNDLKKQKE-ELENELNLLEKEKLNIQKNIDKIKNKLLKLEL 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2021 QLEKMRKFLDEQaidreherDVFQQEIQKLEHQLKavpRIQPVSEHQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQ 2100
Cdd:TIGR04523  202 LLSNLKKKIQKN--------KSLESQISELKKQNN---QLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLS 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2101 ERNEEIEKLECRVRELE---QALLASAEPFPKVEDQKRSGAVEADPElSLEVQLQVERDATDRKQKEITNLEEQLEQFRE 2177
Cdd:TIGR04523  271 EKQKELEQNNKKIKELEkqlNQLKSEISDLNNQKEQDWNKELKSELK-NQEKKLEEIQNQISQNNKIISQLNEQISQLKK 349

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2178 ELENKNDEVQELLMQLEiqrkESTTRLQELQQENrlfkviEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLtgvvE 2257
Cdd:TIGR04523  350 ELTNSESENSEKQRELE----EKQNEIEKLKKEN------QSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQI----K 415

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2258 KLQQEVVSTEQQREgarTLPEDEESFKHQLDKVTAEKLVLEQQVETTNQVMTHMNNVLKEINFKMDQITQSLCNLNKECA 2337
Cdd:TIGR04523  416 KLQQEKELLEKEIE---RLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELK 492

                          490
                   ....*....|..
gi 1039770159 2338 SNE-ELPSLPKE 2348
Cdd:TIGR04523  493 SKEkELKKLNEE 504
PTZ00121 PTZ00121
MAEBL; Provisional
 1822-2472 3.64e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.15  E-value: 3.64e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1822 SETNTQLEHAKVTQTELMRESFRQKQEATESLHCLEELRERLQEESRAREQL--AEELNKAESVIDGYSDEKTLFERQIQ 1899
Cdd:PTZ00121  1136 AEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVrkAEELRKAEDARKAEAARKAEEERKAE 1215

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1900 EKTDIIEHLEQEVLCMNNRLQELESDQRRVEEER-QLLCRQREAMRAEAGPVEQQFLQETEKLMKEKLEvqcQAEKVRgd 1978
Cdd:PTZ00121  1216 EARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERnNEEIRKFEEARMAHFARRQAAIKAEEARKADELK---KAEEKK-- 1290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1979 lqkqvKALEIDVEEQVSRFIEL----EQEKNAEltDLRQQSQALEKQLEKMRKfldeQAIDREHERDVFQQEIQKLEHQL 2054
Cdd:PTZ00121  1291 -----KADEAKKAEEKKKADEAkkkaEEAKKAD--EAKKKAEEAKKKADAAKK----KAEEAKKAAEAAKAEAEAAADEA 1359

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2055 KAVPRIQPVSEHQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDiQERNEEIEKLECRVRELEQA------------LLA 2122
Cdd:PTZ00121  1360 EAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEED-KKKADELKKAAAAKKKADEAkkkaeekkkadeAKK 1438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2123 SAEPFPKVEDQKRSgAVEADPELSLEVQLQVERDATDRKQK-EITNLEEQLEQFREELENKNDEVQ----------ELLM 2191
Cdd:PTZ00121  1439 KAEEAKKADEAKKK-AEEAKKAEEAKKKAEEAKKADEAKKKaEEAKKADEAKKKAEEAKKKADEAKkaaeakkkadEAKK 1517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2192 QLEIQRKESTTRLQELQQENRLFKVIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTgvVEKLQQEVVSTEQQRE 2271
Cdd:PTZ00121  1518 AEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMA--LRKAEEAKKAEEARIE 1595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2272 GARTLPEDEESFK-HQLDKVTAEKLVLEQ--QVETTNQVMTHMNNVLKEINFKMDQITQSlcnlnkecasnEELPSLPKE 2348
Cdd:PTZ00121  1596 EVMKLYEEEKKMKaEEAKKAEEAKIKAEElkKAEEEKKKVEQLKKKEAEEKKKAEELKKA-----------EEENKIKAA 1664

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2349 SVHMTVHElgsDNLQPEDAPAQDVTkplEKQTSLTRLQKSPEASRTQEIESLASSVGAKDVELTQCREQTETIQEQAQSE 2428
Cdd:PTZ00121  1665 EEAKKAEE---DKKKAEEAKKAEED---EKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE 1738

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....
gi 1039770159 2429 TDRLQKKLTDLQRSLEKfaAALVSQVQMEAAQEYVPFHQEKQPV 2472
Cdd:PTZ00121  1739 AEEDKKKAEEAKKDEEE--KKKIAHLKKEEEKKAEEIRKEKEAV 1780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1809-2138 6.08e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 6.08e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1809 RLQAAVEKLLEAISETNTQLEHAKVTQTELmRESFRQKQEATESLhcleelrerLQEESRAREQLAEELNKAESVidgyS 1888
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEEL-EEELEQLRKELEEL---------SRQISALRKDLARLEAEVEQL----E 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1889 DEKTLFERQIQEKTDIIEHLEQevlcmnnRLQELESDQRRVEEERQLLCRQREAMRAEAGPVEQQFLQETEKLMKEKLEV 1968
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEE-------RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEA 819

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1969 QCQAEKVRGdlqkqvkaLEIDVEEQVSRFIELEQEKNaeltDLRQQSQALEKQLEKMRKFLDEQAIDREH---ERDVFQQ 2045
Cdd:TIGR02168  820 ANLRERLES--------LERRIAATERRLEDLEEQIE----ELSEDIESLAAEIEELEELIEELESELEAllnERASLEE 887

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2046 EIQKLEHQLkavpriqpvsEHQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQALLASAE 2125
Cdd:TIGR02168  888 ALALLRSEL----------EELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAE 957

                          330
                   ....*....|...
gi 1039770159 2126 PFPKVEDQKRSGA 2138
Cdd:TIGR02168  958 ALENKIEDDEEEA 970
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2002-2226 6.85e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.85  E-value: 6.85e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2002 QEKNAELTDLRQQSQALEKQLEKMRKfldeqaidrehERDVFQQEIQKLEHQLKAvpriqpvsehQAREVEQLTNHLKEK 2081
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKK-----------EEKALLKQLAALERRIAA----------LARRIRALEQELAAL 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2082 TDRCSELLLSKEQLQRDIQERNEEIEKlecRVRELEQ-------ALLASAEPFPKV------------EDQKRSGAVEAD 2142
Cdd:COG4942     82 EAELAELEKEIAELRAELEAQKEELAE---LLRALYRlgrqpplALLLSPEDFLDAvrrlqylkylapARREQAEELRAD 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2143 PElslevQLQVERDATDRKQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQ-ENRLFKVIEEQK 2221
Cdd:COG4942    159 LA-----ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQeAEELEALIARLE 233


                   ....*
gi 1039770159 2222 EQIQD 2226
Cdd:COG4942    234 AEAAA 238
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1957-2251 7.81e-08

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 58.60  E-value: 7.81e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1957 ETEKLMKEKLEVQCQAEKvRGDLQKQVKALEIDVEEQVSRFIELEQ---EKNAELTDLRQQSQALEKQLEKMRKFLDEQA 2033
Cdd:pfam17380  297 EQERLRQEKEEKAREVER-RRKLEEAEKARQAEMDRQAAIYAEQERmamERERELERIRQEERKRELERIRQEEIAMEIS 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2034 IDREHERDVF--QQEIQKLEHQLKAVPRIQPVSEHQAREVEQLTNHLKEKtdRCSELLLSKEQLQRDIQERNEEIEklec 2111
Cdd:pfam17380  376 RMRELERLQMerQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQI--RAEQEEARQREVRRLEEERAREME---- 449

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2112 RVRELEQALLASAEPFPKVEDQKRSGAVEADPELSLEVQLQ------VERDATDRKQKEItnleeQLEQFREELENKNDE 2185
Cdd:pfam17380  450 RVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEeqrrkiLEKELEERKQAMI-----EEERKRKLLEKEMEE 524

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770159 2186 VQELLMQLEIQRKESTTRLQELQQENRlfKVIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQ 2251
Cdd:pfam17380  525 RQKAIYEEERRREAEEERRKQQEMEER--RRIQEQMRKATEERSRLEAMEREREMMRQIVESEKAR 588
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1804-2302 7.85e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 58.83  E-value: 7.85e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1804 LNISSRLQAAVEKLLEAISETNTQLEHAKVTQTELMRESFRQKQEATESLHCLEELRERLQEESRAREQLAEELNKAESV 1883
Cdd:TIGR00618  402 LDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQI 481

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1884 IDGYSDEKTLFERqiqektdiiehleqevlcmnnRLQELESDQRRVEEerQLLCRQREAMRAEAGPVEQQFLQETEKLMK 1963
Cdd:TIGR00618  482 HLQETRKKAVVLA---------------------RLLELQEEPCPLCG--SCIHPNPARQDIDNPGPLTRRMQRGEQTYA 538

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1964 EKLEVQcqaEKVRGDLQKQVKALEIDvEEQVSRFIELEQEKNAELTDLRQQSQALEKQLEKMRKFLDEQAIDREHERDVF 2043
Cdd:TIGR00618  539 QLETSE---EDVYHQLTSERKQRASL-KEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQ 614

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2044 QQEIQKLEHQLkavpriqpvsehqarEVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLecRVRELEQALLAS 2123
Cdd:TIGR00618  615 HALLRKLQPEQ---------------DLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHAL--SIRVLPKELLAS 677

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2124 AEPFPKVEDQKRSGAVEADPELS-LEVQLQVERDATDRKQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTT 2202
Cdd:TIGR00618  678 RQLALQKMQSEKEQLTYWKEMLAqCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLK 757

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2203 RLQELQQENRLFKVIEEQkeqiqdLETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQRE-GARTLPEDEE 2281
Cdd:TIGR00618  758 ARTEAHFNNNEEVTAALQ------TGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNlQCETLVQEEE 831

                          490       500
                   ....*....|....*....|.
gi 1039770159 2282 SFKHQLDKVTAEKLVLEQQVE 2302
Cdd:TIGR00618  832 QFLSRLEEKSATLGEITHQLL 852
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1810-2258 1.03e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 58.11  E-value: 1.03e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1810 LQAAVEKLLEAISETNTQLEHAKVTQTELMRESFRQKQEATES----LHCLEELRERLQEESRAREQLAEELNKA-ESVI 1884
Cdd:TIGR04523  237 KQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNnkkiKELEKQLNQLKSEISDLNNQKEQDWNKElKSEL 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1885 DGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEagpvEQQFLQETEKLMKE 1964
Cdd:TIGR04523  317 KNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKE----NQSYKQEIKNLESQ 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1965 K--LEVQCQ-AEKVRGDLQKQVKALEID---VEEQVSRFIELEQEKNAELTDLRQQSQALEKQLEKMRKFLDEQaidrEH 2038
Cdd:TIGR04523  393 IndLESKIQnQEKLNQQKDEQIKKLQQEkelLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESL----ET 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2039 ERDVFQQEIQKLEHQLKAVPR--IQPVSEHQA--REVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVR 2114
Cdd:TIGR04523  469 QLKVLSRSINKIKQNLEQKQKelKSKEKELKKlnEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELN 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2115 ELEQALlasaePFPKVEDQKrsgaveadpelslevqlqverdatDRKQKEItnleEQLEQFREELENKNDEVQELLMQLE 2194
Cdd:TIGR04523  549 KDDFEL-----KKENLEKEI------------------------DEKNKEI----EELKQTQKSLKKKQEEKQELIDQKE 595

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039770159 2195 IQRKESTTRLQEL-QQENRLFKVIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEK 2258
Cdd:TIGR04523  596 KEKKDLIKEIEEKeKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNK 660
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 288-836 1.32e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 57.81  E-value: 1.32e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  288 EMEKDRKIENLNAKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQNER 367
Cdd:pfam05483  107 KLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYM 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  368 KCSEEIKELMRTVEELqkrnlkdswletsavrRVEQETQRKLSHLQAELDEMYGKQIVQMKQELINQHMSQIEELKSQhK 447
Cdd:pfam05483  187 DLNNNIEKMILAFEEL----------------RVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQ-I 249

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  448 REMENTLKSDTNA-AISKEQVNLMNAAINELNVRLQETHAQKEELKGELGVVlgeKSALQSQsndlLEEVRFLREQVQKA 526
Cdd:pfam05483  250 TEKENKMKDLTFLlEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDI---KMSLQRS----MSTQKALEEDLQIA 322

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  527 RQTI----AEQENRLSEARKSLSTVEDLKAEIVAASESRKELELKHEAEITNYKIKLEMLEKE---KNAVLDRMAE---S 596
Cdd:pfam05483  323 TKTIcqltEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMElqkKSSELEEMTKfknN 402

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  597 QEAELERLRT-----QLLFSHEEELSKLKEDLEVEHRINI------EKLKDNLGI----------HYKQQIDGLQNEMNR 655
Cdd:pfam05483  403 KEVELEELKKilaedEKLLDEKKQFEKIAEELKGKEQELIfllqarEKEIHDLEIqltaiktseeHYLKEVEDLKTELEK 482

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  656 ---KMESMQCETDNLITQQNQLILENS----KLRDLQECLVNSKSEE--MNLQINELQ-KEIEILKQEEKEKGTLEQEVQ 725
Cdd:pfam05483  483 eklKNIELTAHCDKLLLENKELTQEASdmtlELKKHQEDIINCKKQEerMLKQIENLEeKEMNLRDELESVREEFIQKGD 562

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  726 ELQLKTEQLEKQLKEKEDDLQEKCAQLDAENNILKEEKRVLEDKLKMYSPSEQEERSIAVDPSTSKSADSRWQKEVAMLR 805
Cdd:pfam05483  563 EVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLE 642

                          570       580       590
                   ....*....|....*....|....*....|.
gi 1039770159  806 KETEDLQQQCLYLNEEIEKQRNTFAFAEKNF 836
Cdd:pfam05483  643 LELASAKQKFEEIIDNYQKEIEDKKISEEKL 673
PTZ00121 PTZ00121
MAEBL; Provisional
 1821-2307 1.36e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.23  E-value: 1.36e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1821 ISETNTQLEHAKVTQTELMRESFRQKQEATESLHCLEELRERLQEESRARE-QLAEELNKAESVIDGYSDEKTLFERQIQ 1899
Cdd:PTZ00121  1232 AEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADElKKAEEKKKADEAKKAEEKKKADEAKKKA 1311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1900 EKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEAGPVEQQflQETEKLMKEKLEVQCQAEKVRGDL 1979
Cdd:PTZ00121  1312 EEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK--AEAAEKKKEEAKKKADAAKKKAEE 1389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1980 QKQVKALEIDVEEQVSRFIEL----EQEKNAE----LTDLRQQSQALEKQLEKMRKflDEQAIDREHERDVFQQEIQKLE 2051
Cdd:PTZ00121  1390 KKKADEAKKKAEEDKKKADELkkaaAAKKKADeakkKAEEKKKADEAKKKAEEAKK--ADEAKKKAEEAKKAEEAKKKAE 1467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2052 HQLKAVPRIQPVSEhqAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQAllASAEPFPKVE 2131
Cdd:PTZ00121  1468 EAKKADEAKKKAEE--AKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEA--KKADEAKKAE 1543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2132 DQKRSGAVEADPEL-SLEVQLQVE--RDATDRKQKEITNLEE--QLEQFREELENKNDEvQELLMQLEIQRKESTTRL-- 2204
Cdd:PTZ00121  1544 EKKKADELKKAEELkKAEEKKKAEeaKKAEEDKNMALRKAEEakKAEEARIEEVMKLYE-EEKKMKAEEAKKAEEAKIka 1622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2205 -------QELQQENRLFKVIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQltgvVEKLQQEvvsTEQQREGARTLP 2277
Cdd:PTZ00121  1623 eelkkaeEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKK----AEEAKKA---EEDEKKAAEALK 1695

                          490       500       510
                   ....*....|....*....|....*....|..
gi 1039770159 2278 EDEESFK--HQLDKVTAEKLVLEQQVETTNQV 2307
Cdd:PTZ00121  1696 KEAEEAKkaEELKKKEAEEKKKAEELKKAEEE 1727
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1991-2298 1.95e-07

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 57.24  E-value: 1.95e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1991 EEQVSRFIELEQEKNAE-LTDLRQQSQALEKQLEKMRKFLDEQAIDREherdvfqqEIQKLEHQlkavpriqpvsehqar 2069
Cdd:PRK05771    27 ELGVVHIEDLKEELSNErLRKLRSLLTKLSEALDKLRSYLPKLNPLRE--------EKKKVSVK---------------- 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2070 EVEQLTNHLKEKtdrcselllsKEQLQRDIQERNEEIEKLECRVRELEQaLLASAEPFpkvedqkrsGAVEADPELSLE- 2148
Cdd:PRK05771    83 SLEELIKDVEEE----------LEKIEKEIKELEEEISELENEIKELEQ-EIERLEPW---------GNFDLDLSLLLGf 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2149 --VQLQVERdaTDRKQKEITNLEEQLEQFREELENKN-------------DEVQELLMQLEIQRkesttrlQELQQENRL 2213
Cdd:PRK05771   143 kyVSVFVGT--VPEDKLEELKLESDVENVEYISTDKGyvyvvvvvlkelsDEVEEELKKLGFER-------LELEEEGTP 213

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2214 FKVIEEQKEQIQDLETQIERLmseREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQREGART---------LPEDE-ESF 2283
Cdd:PRK05771   214 SELIREIKEELEEIEKERESL---LEELKELAKKYLEELLALYEYLEIELERAEALSKFLKTdktfaiegwVPEDRvKKL 290

                          330
                   ....*....|....*
gi 1039770159 2284 KHQLDKVTAEKLVLE 2298
Cdd:PRK05771   291 KELIDKATGGSAYVE 305
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1905-2207 2.17e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 2.17e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1905 IEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAmraeagpveqqfLQETEKLMKEKLEVQcQAEKVRGDLQKQVK 1984
Cdd:COG4913    612 LAALEAELAELEEELAEAEERLEALEAELDALQERREA------------LQRLAEYSWDEIDVA-SAEREIAELEAELE 678

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1985 ALEidveeqvsrfieleqEKNAELTDLRQQSQALEKQLEKMRKFLDEQAIDR---EHERDVFQQEIQKLEHQLKAVPRIQ 2061
Cdd:COG4913    679 RLD---------------ASSDDLAALEEQLEELEAELEELEEELDELKGEIgrlEKELEQAEEELDELQDRLEAAEDLA 743

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2062 PVSEHqarevEQLTNHLKEKTDRCSELLLSkEQLQRDIQERNEEIEKLEcrvRELEQALLASAEPFPkvedqkrSGAVEA 2141
Cdd:COG4913    744 RLELR-----ALLEERFAAALGDAVERELR-ENLEERIDALRARLNRAE---EELERAMRAFNREWP-------AETADL 807

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039770159 2142 DPELSlevqlqvERDATDRKQKEITN--LEEQLEQFREEL-ENKNDEVQELLMQLEIQRKESTTRLQEL 2207
Cdd:COG4913    808 DADLE-------SLPEYLALLDRLEEdgLPEYEERFKELLnENSIEFVADLLSKLRRAIREIKERIDPL 869
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2031-2273 2.40e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.31  E-value: 2.40e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2031 EQAIDREHERDVFQQEIQKLEHQLKAvpriqpvsehQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLE 2110
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAA----------LKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2111 CRVRELEQALLASAEPFPKV--EDQKRSGAVEADPELSLEVQLQVERDATDRKQkeitnLEEQLEQFREELENKNDEVQE 2188
Cdd:COG4942     90 KEIAELRAELEAQKEELAELlrALYRLGRQPPLALLLSPEDFLDAVRRLQYLKY-----LAPARREQAEELRADLAELAA 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2189 LLMQLEIQRKESTTRLQELQQENrlfKVIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEVVSTEQ 2268
Cdd:COG4942    165 LRAELEAERAELEALLAELEEER---AALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241


                   ....*
gi 1039770159 2269 QREGA 2273
Cdd:COG4942    242 RTPAA 246
PTZ00121 PTZ00121
MAEBL; Provisional
 1832-2288 2.49e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.46  E-value: 2.49e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1832 KVTQTELMRESFRQKQEATESLHCLEELRERLQEESRAREQLAEELNKAESVIDGYSDEKTLFERQiqEKTDIIEHLEQE 1911
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEK--KKADEAKKKAEE 1442

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1912 vlcmNNRLQELESDQRRVEEERQLLCRQREAMRAEAGPVEQQFLQETEKLMKEKLEVQCQAEKVRGDLQKQVKALEIDVE 1991
Cdd:PTZ00121  1443 ----AKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA 1518

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1992 EQVSRFIELEQEKNAELTDLRQQSQALEKQlEKMRKfldEQAIDREHERDVFQQEIQKLEHQLKAVPRIQPVSEHQAREV 2071
Cdd:PTZ00121  1519 EEAKKADEAKKAEEAKKADEAKKAEEKKKA-DELKK---AEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARI 1594

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2072 EQLTNHLKEktdrcsELLLSKEQLQRDIQERN--EEIEKLECRVRELEQALLASAEPFPKVEDQKRsgaveADPELSLEV 2149
Cdd:PTZ00121  1595 EEVMKLYEE------EKKMKAEEAKKAEEAKIkaEELKKAEEEKKKVEQLKKKEAEEKKKAEELKK-----AEEENKIKA 1663

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2150 QLQVERDATDRKQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENRLFKV-IEEQKEQIQDLE 2228
Cdd:PTZ00121  1664 AEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIkAEEAKKEAEEDK 1743

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039770159 2229 TQIERLMSEREHEKK--QREEEVEQLTGVVEKLQQEVVSTEQQREGARTLPEDEESFKHQLD 2288
Cdd:PTZ00121  1744 KKAEEAKKDEEEKKKiaHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFD 1805
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1988-2306 2.50e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 57.06  E-value: 2.50e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1988 IDVEEQVSRFIELEQEKnaeltdLRQQSQALEKQLEKMRKF----------LDEQA-IDREHERDVFQQEiqklehqlKA 2056
Cdd:pfam17380  284 VSERQQQEKFEKMEQER------LRQEKEEKAREVERRRKLeeaekarqaeMDRQAaIYAEQERMAMERE--------RE 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2057 VPRIQpvSEHQAREVEQL-TNHLKEKTDRCSELllskEQLQRDIQERNEeieklecRVRELeqalLASAEPFPKVEDQKR 2135
Cdd:pfam17380  350 LERIR--QEERKRELERIrQEEIAMEISRMREL----ERLQMERQQKNE-------RVRQE----LEAARKVKILEEERQ 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2136 SGAVEADPELSlevqlQVERDATDRKQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENRLFK 2215
Cdd:pfam17380  413 RKIQQQKVEME-----QIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRK 487

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2216 VIEEQKEQIQD----------LETQIERLMSEREHEKKQR---EEEVEQLTGVVEKLQQEVVSTEQQREGARTLPEDees 2282
Cdd:pfam17380  488 RAEEQRRKILEkeleerkqamIEEERKRKLLEKEMEERQKaiyEEERRREAEEERRKQQEMEERRRIQEQMRKATEE--- 564

                          330       340
                   ....*....|....*....|....
gi 1039770159 2283 fKHQLDKVTAEKLVLEQQVETTNQ 2306
Cdd:pfam17380  565 -RSRLEAMEREREMMRQIVESEKA 587
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2897-3198 2.86e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.99  E-value: 2.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2897 LEQRIQEQGIEYHTAMDCLQ--KADRRSLLAEIEDLRAQINGGKMTLER-----EQGTEKSSQELLDCSMQQKQSLEMQL 2969
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEelEEELEQLRKELEELSRQISALRKDLARleaevEQLEERIAQLSKELTELEAEIEELEE 768

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2970 ELSSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELgTTLKAQHKRLKE--------LEAFRSEVKEKTDEIHFLSDTL 3041
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREAL-DELRAELTLLNEeaanlrerLESLERRIAATERRLEDLEEQI 847

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3042 AREQKNSLELQWALEKEKArsghhegrEKEELEDLKFSLEDQKRRNTQLNLLLEQQKQLLNESQQKIESQKMLHDAQLSE 3121
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEE--------LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE 919

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039770159 3122 EQGRNLGLQALLESEQVRIQEMKSTLdkeRELYaQLQSREDGGQPPPALPSEDLLKELQKQLEEKHSRI--VELLSETE 3198
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDNLQERL---SEEY-SLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpVNLAAIEE 994
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 268-615 2.98e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.00  E-value: 2.98e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  268 KKEEDLQAQISFLQEKLRAFEMEKDRKIENLNAKEIQEKQALIdELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQ 347
Cdd:TIGR02169  184 ENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGY-ELLKEKEALERQKEAIERQLASLEEELEKLTEEISE 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  348 RNQEIQSLKLELGN-SQQNERKCSEEIKELMRTVEELQkrnlkdswLETSAVRRVEQETQRKLSHLQAELdemygkqivQ 426
Cdd:TIGR02169  263 LEKRLEEIEQLLEElNKKIKDLGEEEQLRVKEKIGELE--------AEIASLERSIAEKERELEDAEERL---------A 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  427 MKQELINQHMSQIEELKSQhkREMENTLKSDTNAAISKEQvnlmnAAINELNVRLQETHAQKEELKGELGVVLGEKSALQ 506
Cdd:TIGR02169  326 KLEAEIDKLLAEIEELERE--IEEERKRRDKLTEEYAELK-----EELEDLRAELEEVDKEFAETRDELKDYREKLEKLK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  507 SQSNDLLEEVRFLREQVQKARQTIAEQENRLSEARKSL----STVEDLKAEIVAASESRKELelkhEAEITNYKIKLEML 582
Cdd:TIGR02169  399 REINELKRELDRLQEELQRLSEELADLNAAIAGIEAKIneleEEKEDKALEIKKQEWKLEQL----AADLSKYEQELYDL 474

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1039770159  583 EKEKNAVLDRMAESQEaELERLRTQLLFSHEEE 615
Cdd:TIGR02169  475 KEEYDRVEKELSKLQR-ELAEAEAQARASEERV 506
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1819-2117 3.09e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 56.67  E-value: 3.09e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1819 EAISETNTQLEHAKVTQTELMRESFRQKQEATESLHCLEELRERLQEESRAREQLAEELNKAesvidgYSDEKTLFERQI 1898
Cdd:pfam17380  282 KAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMA------MERERELERIRQ 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1899 QEKTDIIEHLEQEVLCMN-NRLQELEsdqrRVEEERQllcRQREAMRAEAGPVEQQFLQETEK------LMKEKLEVQCQ 1971
Cdd:pfam17380  356 EERKRELERIRQEEIAMEiSRMRELE----RLQMERQ---QKNERVRQELEAARKVKILEEERqrkiqqQKVEMEQIRAE 428

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1972 AEKVRgdlQKQVKALEIDVEEQVSRFIELEQEKNAELTDLRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQK-- 2049
Cdd:pfam17380  429 QEEAR---QREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEErk 505

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039770159 2050 ---LEHQLKAVPRIQPVSEHQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELE 2117
Cdd:pfam17380  506 qamIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMERERE 576
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1868-2276 3.09e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.85  E-value: 3.09e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1868 RAREQLAEELNKAESVIDGYSDEKTlfERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLcrqREAMRAEA 1947
Cdd:COG4913    262 ERYAAARERLAELEYLRAALRLWFA--QRRLELLEAELEELRAELARLEAELERLEARLDALREELDEL---EAQIRGNG 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1948 GPVEQQFLQETEKLMKEKLEVqcqaEKVRGDLQKQVKALEIDVEEQVSRFIELEQEKNAELTDLRQQSQALEKQLEKmrk 2027
Cdd:COG4913    337 GDRLEQLEREIERLERELEER----ERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAE--- 409

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2028 fLDEQAIDREHERDVFQQEIQKLEHQLKAVPRiqpvSEHQAREveQLTNHLKEKTDRC---SELLlskeqlqrDIQERNE 2104
Cdd:COG4913    410 -AEAALRDLRRELRELEAEIASLERRKSNIPA----RLLALRD--ALAEALGLDEAELpfvGELI--------EVRPEEE 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2105 E----IE---------------------------KLECRVR-----------------------ELE----------QAL 2120
Cdd:COG4913    475 RwrgaIErvlggfaltllvppehyaaalrwvnrlHLRGRLVyervrtglpdperprldpdslagKLDfkphpfrawlEAE 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2121 LASAEPFPKVEDQK-----------------RSGAVEADPELSLEVQLQVERDATDR---KQKEITNLEEQLEQFREELE 2180
Cdd:COG4913    555 LGRRFDYVCVDSPEelrrhpraitragqvkgNGTRHEKDDRRRIRSRYVLGFDNRAKlaaLEAELAELEEELAEAEERLE 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2181 nkndEVQELLMQLEIQRkestTRLQELQQENRLFKVIEEQKEQIQDLETQIERLMS------EREHEKKQREEEVEQLTG 2254
Cdd:COG4913    635 ----ALEAELDALQERR----EALQRLAEYSWDEIDVASAEREIAELEAELERLDAssddlaALEEQLEELEAELEELEE 706

                          490       500
                   ....*....|....*....|..
gi 1039770159 2255 VVEKLQQEVVSTEQQREGARTL 2276
Cdd:COG4913    707 ELDELKGEIGRLEKELEQAEEE 728
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1872-2348 4.01e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 56.59  E-value: 4.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1872 QLAEELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRV-EEERQLLCRQREAMRAEAGPV 1950
Cdd:TIGR00606  416 DLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRIlELDQELRKAERELSKAEKNSL 495

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1951 EQQFLQETEKLMKEKLEV--------QCQAEKVR-GDLQKQVKALEIDVEEQVSRFIELEQEKNAELTDLR---QQSQAL 2018
Cdd:TIGR00606  496 TETLKKEVKSLQNEKADLdrklrkldQEMEQLNHhTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLgyfPNKKQL 575

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2019 EKQLEKMRKfldEQAIDREHERDVfQQEIQKLEHQlkavpriqpvSEHQAREVEQLTNHLKEKTDRCSElLLSKEQLQRD 2098
Cdd:TIGR00606  576 EDWLHSKSK---EINQTRDRLAKL-NKELASLEQN----------KNHINNELESKEEQLSSYEDKLFD-VCGSQDEESD 640

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2099 IQERNEEIEKLECRVRELEQALLASAEPFPKVEDQKRSGAVEADPELSLEVQLQVERDATDRKQKEITNLEEQLEQFREE 2178
Cdd:TIGR00606  641 LERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKK 720

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2179 LENKNDEVQEL--LMQLEIQRKESttRLQELQQENR-LFKVIEEQKEQIQDLETQIERLMSEREHEKKQRE-----EEVE 2250
Cdd:TIGR00606  721 KEKRRDEMLGLapGRQSIIDLKEK--EIPELRNKLQkVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTdvtimERFQ 798

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2251 QLTGVVEKLQQEVVSTEQQREGARTLPE---DEESFKHQLDKVTAEKLVLEQQVETTNQVMTHMNNVLKEINFKMDQITQ 2327
Cdd:TIGR00606  799 MELKDVERKIAQQAAKLQGSDLDRTVQQvnqEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGT 878

                          490       500
                   ....*....|....*....|.
gi 1039770159 2328 slcNLNKECASNEELPSLPKE 2348
Cdd:TIGR00606  879 ---NLQRRQQFEEQLVELSTE 896
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1808-2320 4.44e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.46  E-value: 4.44e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1808 SRLQAAVEK------LLEAISETNTQLEHAKVTQTEL--MRESFRQKQEATEslhcleelrerLQEESRAREQLAEELNK 1879
Cdd:COG4913    238 ERAHEALEDareqieLLEPIRELAERYAAARERLAELeyLRAALRLWFAQRR-----------LELLEAELEELRAELAR 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1880 AEsvidgysDEKTLFERQIQEKTDIIEHLEQEVLcmNN---RLQELESDQRRVEEERQLLCRQREAMRAEAGPVEQQFLQ 1956
Cdd:COG4913    307 LE-------AELERLEARLDALREELDELEAQIR--GNggdRLEQLEREIERLERELEERERRRARLEALLAALGLPLPA 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1957 ETEKLmkekLEVQCQAEKVRGDLQKQVKALEIDVEEQVSRFIELEQEKN---AELTDLRQQSQALEKQLEKMRKFLDEQ- 2032
Cdd:COG4913    378 SAEEF----AALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELReleAEIASLERRKSNIPARLLALRDALAEAl 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2033 -------------------------AIDR-------------EHERDV--------FQQEI--QKLEHQLKAVPRIQP-- 2062
Cdd:COG4913    454 gldeaelpfvgelievrpeeerwrgAIERvlggfaltllvppEHYAAAlrwvnrlhLRGRLvyERVRTGLPDPERPRLdp 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2063 --------VSEHQARE-----------------VEQLTNH---------------LKEKTDR---CSELLL------SKE 2093
Cdd:COG4913    534 dslagkldFKPHPFRAwleaelgrrfdyvcvdsPEELRRHpraitragqvkgngtRHEKDDRrriRSRYVLgfdnraKLA 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2094 QLQRDIQERNEEIEKLECRVRELEQALLASAEPFPKVEDQKRSGAVEAD-PELSLEV-QLQVERDATDRKQKEITNLEEQ 2171
Cdd:COG4913    614 ALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDvASAEREIaELEAELERLDASSDDLAALEEQ 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2172 LEQFREELENKNDEVQEL---LMQLEIQRKESTTRLQELQQENRLFkVIEEQKEQIQDLETQIERLMSEREHEKKQR--E 2246
Cdd:COG4913    694 LEELEAELEELEEELDELkgeIGRLEKELEQAEEELDELQDRLEAA-EDLARLELRALLEERFAAALGDAVERELREnlE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2247 EEVEQLTGVVEKLQQEVVS------------------------------TEQQREGartLPEDEESFKHQLDKVTAEKLV 2296
Cdd:COG4913    773 ERIDALRARLNRAEEELERamrafnrewpaetadldadleslpeylallDRLEEDG---LPEYEERFKELLNENSIEFVA 849

                          650       660
                   ....*....|....*....|....*....
gi 1039770159 2297 -----LEQQVETTNQVMTHMNNVLKEINF 2320
Cdd:COG4913    850 dllskLRRAIREIKERIDPLNDSLKRIPF 878
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1544-2109 5.25e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.10  E-value: 5.25e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1544 LNEQLEDMRQELVRQYEEHQQATEMLRQAHM------QQMERQREDQEQLQEEIKRLNEQLAQ-KSSIDTEHVVSERERV 1616
Cdd:COG1196    265 LEAELEELRLELEELELELEEAQAEEYELLAelarleQDIARLEERRRELEERLEELEEELAElEEELEELEEELEELEE 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1617 LLEELEALKQLPLAGRKELCCELRHSSTQTQDGHDDQEVEEQTLKDKTLERSpEDALLDRNLSNERYALKKANNRLLKIL 1696
Cdd:COG1196    345 ELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAA-ELAAQLEELEEAEEALLERLERLEEEL 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1697 LEVVKTTSAAEETIGRHVLGILDRSSKGQTASSLLWRSEADASATTCAPEDCARAMDEsipsypgtaiaTHDSIWSKVTE 1776
Cdd:COG1196    424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE-----------LLEELAEAAAR 492

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1777 EGAELSQRLVRSGFAGPVIDPENEELMLNISSRLQ------AAVEKLLEAISETNTQLEHAKVTQTELMRESF--RQKQE 1848
Cdd:COG1196    493 LLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAvligveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYlkAAKAG 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1849 ATESLHCLEELRERLQEESRAREQLAEELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQEvlcmNNRLQELESDQRR 1928
Cdd:COG1196    573 RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA----LRRAVTLAGRLRE 648

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1929 VEEERQLLcRQREAMRAEAGPVEQQFLQETEKLMKEKLEVQCQAEKVRGDLQKQVKALEIDVEEQVSRFIELEQEKNAEL 2008
Cdd:COG1196    649 VTLEGEGG-SAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALE 727

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2009 TDLRQQSQALEKQLEKMRKFLDEQAIDREHE---RDVFQQEIQKLEHQLKAVPRIQPVSEHQAREVEQLTNHLKEKTDrc 2085
Cdd:COG1196    728 EQLEAEREELLEELLEEEELLEEEALEELPEppdLEELERELERLEREIEALGPVNLLAIEEYEELEERYDFLSEQRE-- 805

                          570       580
                   ....*....|....*....|....
gi 1039770159 2086 sELLLSKEQLQRDIQERNEEIEKL 2109
Cdd:COG1196    806 -DLEEARETLEEAIEEIDRETRER 828
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
146-639 5.63e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.84  E-value: 5.63e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  146 VEKELAEKQHDIEELTQELEEMRASFGT------------EGLKQLQEFEAAIKQRDGIITQLTANLQQARREKDDTMVE 213
Cdd:PRK03918   198 KEKELEEVLREINEISSELPELREELEKlekevkeleelkEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEE 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  214 FLELTEQSQKLQiqfqhlqaNETLQNSTLSRTATDLLQAKRQIftqqqqlqdyQKKEEDLQAQISFLQEKLrafemekdr 293
Cdd:PRK03918   278 LEEKVKELKELK--------EKAEEYIKLSEFYEEYLDELREI----------EKRLSRLEEEINGIEERI--------- 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  294 kienlnaKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLH--EQLTQR--NQEIQSLKLELGNSQQNERKC 369
Cdd:PRK03918   331 -------KELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEelERLKKRltGLTPEKLEKELEELEKAKEEI 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  370 SEEIKELMRTVEELQKR--NLKDSWLETSAVRRVEQETQRKLS-HLQAELDEMYGKQIVQMKQELInQHMSQIEELKSQh 446
Cdd:PRK03918   404 EEEISKITARIGELKKEikELKKAIEELKKAKGKCPVCGRELTeEHRKELLEEYTAELKRIEKELK-EIEEKERKLRKE- 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  447 KREMENTLKSDTNAAISKEQVNLMNAAINELNV----RLQETHAQKEELKGELGVVLGEKSALQS---QSNDLLEEVRFL 519
Cdd:PRK03918   482 LRELEKVLKKESELIKLKELAEQLKELEEKLKKynleELEKKAEEYEKLKEKLIKLKGEIKSLKKeleKLEELKKKLAEL 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  520 REQVQKARQTIAEQENRLSEarKSLSTVEDLKAEI----------VAASESRKELELKHE-------------AEITNYK 576
Cdd:PRK03918   562 EKKLDELEEELAELLKELEE--LGFESVEELEERLkelepfyneyLELKDAEKELEREEKelkkleeeldkafEELAETE 639

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770159  577 IKLEMLEKEKNAVLDRMAESQEAELERLRTQL---LFSHEEELSKLKEDLEvEHRINIEKLKDNLG 639
Cdd:PRK03918   640 KRLEELRKELEELEKKYSEEEYEELREEYLELsreLAGLRAELEELEKRRE-EIKKTLEKLKEELE 704
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2965-3257 7.67e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.45  E-value: 7.67e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2965 LEMQLELSSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELGTTLKAQHKRLKELEAFRSEVKEKTDEIHFLSDTLARE 3044
Cdd:TIGR02168  673 LERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3045 QKNSLELQWALEKEKARsghhegreKEELEDLKFSLEDQKRRNTQLNLLLEQQKQLLNESQQKIESQKMLHDAQLSEEQG 3124
Cdd:TIGR02168  753 SKELTELEAEIEELEER--------LEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRE 824

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3125 RNLGLQALLESEQVRIQEMKSTLDKERELYAQLQSRedggqpppalpsedlLKELQKQLEEKHSRIVELLSETEKykldS 3204
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAE---------------IEELEELIEELESELEALLNERAS----L 885

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039770159 3205 LQTRQQMEKDRQVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQQV 3257
Cdd:TIGR02168  886 EEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRI 938
PTZ00121 PTZ00121
MAEBL; Provisional
 146-826 7.93e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.53  E-value: 7.93e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  146 VEKELAEKQHDIEELTQELEEMRASFGTEGLKQLQEFEAAIKQRDGIITQLTANLQQARREKDDTMVEFLELTEQSQKLQ 225
Cdd:PTZ00121  1088 RADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAE 1167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  226 IqfqhlqanetlqnstlSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAqisfLQEKLRAfemEKDRKIENLNAKEiQE 305
Cdd:PTZ00121  1168 E----------------ARKAEDAKKAEAARKAEEVRKAEELRKAEDARK----AEAARKA---EEERKAEEARKAE-DA 1223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  306 KQAlidELNTRVVEEEKKTVELK--NKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEIK-------EL 376
Cdd:PTZ00121  1224 KKA---EAVKKAEEAKKDAEEAKkaEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKadeakkaEE 1300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  377 MRTVEELQKRnlKDSWLETSAVRRVEQETQRKLSHLQAELDEMYGK-QIVQMKQELINQHMSQIEELKSQHKREMENTLK 455
Cdd:PTZ00121  1301 KKKADEAKKK--AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAaEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKK 1378

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  456 SDTNAAISKEQVNlmnaAINELNVRLQETHAQKEELKgelgvvlgEKSALQSQSndllEEVRFLREQVQKARQTI--AEQ 533
Cdd:PTZ00121  1379 KADAAKKKAEEKK----KADEAKKKAEEDKKKADELK--------KAAAAKKKA----DEAKKKAEEKKKADEAKkkAEE 1442

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  534 ENRLSEARKSLSTVEDLKAEIVAASESRKELELKHEAEitnykiklemlEKEKNAVLDRMAESQEAELERLRTQllfshE 613
Cdd:PTZ00121  1443 AKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAE-----------EAKKADEAKKKAEEAKKKADEAKKA-----A 1506

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  614 EELSKLKEDLEVEHRINIEKLKdnlgihykqqidglQNEMNRKMESMQCETDNLITQQNQLILENSKLRDLQECLVNSKS 693
Cdd:PTZ00121  1507 EAKKKADEAKKAEEAKKADEAK--------------KAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKA 1572

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  694 EEMNlqiNELQKEIEILKQEEKEK--GTLEQEVQELQLKTEQLEKQlkEKEDDLQEKCAQLDAENNILKEEKRVLEDKLK 771
Cdd:PTZ00121  1573 EEDK---NMALRKAEEAKKAEEARieEVMKLYEEEKKMKAEEAKKA--EEAKIKAEELKKAEEEKKKVEQLKKKEAEEKK 1647

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1039770159  772 MYSPSEQEERSIAVDPSTSKSADSRWQKEVAMLRKETEDLQQQCLYLNEEIEKQR 826
Cdd:PTZ00121  1648 KAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAK 1702
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 150-964 8.04e-07

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 55.57  E-value: 8.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  150 LAEKQHDIEELTQELEEMRASFG---TEGLKQLQEFEAAIKQRDGIITQLTANLQQARREKDDTMVEFLELTEQSQKLQI 226
Cdd:pfam01576   45 LQEQLQAETELCAEAEEMRARLAarkQELEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQL 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  227 QFQHLQA------NETL----QNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDL----QAQISFLQEKLRA-----F 287
Cdd:pfam01576  125 EKVTTEAkikkleEDILlledQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLknkhEAMISDLEERLKKeekgrQ 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  288 EMEKDRKIENLNAKEIQEK----QALIDELNTRVVEEEKktvELKNKVTTADElLGGLHEQLTQRNQEIQSLKLELGNSQ 363
Cdd:pfam01576  205 ELEKAKRKLEGESTDLQEQiaelQAQIAELRAQLAKKEE---ELQAALARLEE-ETAQKNNALKKIRELEAQISELQEDL 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  364 QNERKCSEEIKELMRTV-EELQ--KRNLKDSWLETSAVRRVEQETQRKLSHLQAELDEMYGKQIVQMkQELINQHMSQIE 440
Cdd:pfam01576  281 ESERAARNKAEKQRRDLgEELEalKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQL-QEMRQKHTQALE 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  441 ELKSQHKREMENTLKSDTNAAISKEQVNLMNAAINELNVRLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLR 520
Cdd:pfam01576  360 ELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQ 439

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  521 EQVQKARQTIAEQENRLSEARKSLSTVED--LKAEIVAASESRKELELKHeaeitnykiKLEMLEKEKNAVLDRMAESQE 598
Cdd:pfam01576  440 SELESVSSLLNEAEGKNIKLSKDVSSLESqlQDTQELLQEETRQKLNLST---------RLRQLEDERNSLQEQLEEEEE 510

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  599 A------ELERLRTQL-------------LFSHEEELSKLKEDLE---------VEHRINIEKLKDNLgihyKQQIDGL- 649
Cdd:pfam01576  511 AkrnverQLSTLQAQLsdmkkkleedagtLEALEEGKKRLQRELEaltqqleekAAAYDKLEKTKNRL----QQELDDLl 586

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  650 -----QNEMNRKMESMQCETDNLITQQNQLILENSKLRDLQECLVNSKS----------EEMNLQINELQKEIEILKQE- 713
Cdd:pfam01576  587 vdldhQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKEtralslaralEEALEAKEELERTNKQLRAEm 666

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  714 -----------------EKEKGTLEQEVQELQLKTEQLEKQLKEKED-------DLQEKCAQ----LDAENNILKEEKRV 765
Cdd:pfam01576  667 edlvsskddvgknvhelERSKRALEQQVEEMKTQLEELEDELQATEDaklrlevNMQALKAQferdLQARDEQGEEKRRQ 746

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  766 LEDKLKMYSPSEQEERSIAVDPSTSKsadsrwqKEVAMLRKETEDLQQQCLYLNEEIEKQRntfafaeKNFEVNYQELQR 845
Cdd:pfam01576  747 LVKQVRELEAELEDERKQRAQAVAAK-------KKLELDLKELEAQIDAANKGREEAVKQL-------KKLQAQMKDLQR 812

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  846 EYTCLLKIRDDLEAtqtkQALEYESKLRALEEELLSKRGNPAApkgkssgifpSETLEIGEVVEKDttELMEKL------ 919
Cdd:pfam01576  813 ELEEARASRDEILA----QSKESEKKLKNLEAELLQLQEDLAA----------SERARRQAQQERD--ELADEIasgasg 876

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*.
gi 1039770159  920 -EVTKREKLELSEKVSGLSEQLKQTHCTINSLSAEVRALKQEKEQL 964
Cdd:pfam01576  877 kSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQL 922
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1808-2109 8.39e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.46  E-value: 8.39e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1808 SRLQAAVEKLLEAISETNTQLEHAKVTQTELMRESFRQKQEATESLHCLEELRERLQEESRAREQLAEELNKAESVIDGY 1887
Cdd:TIGR02169  698 RRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKL 777

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1888 SD-----EKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLL-------------CRQREAMRAEAGP 1949
Cdd:TIGR02169  778 EEalndlEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLekeiqelqeqridLKEQIKSIEKEIE 857

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1950 VEQQFLQETEKLMKEKLEVQCQAEKVRGDLQKQVKALEIDVEEQVSRFIELE---QEKNAELTDLRQQSQALEKQLEKMR 2026
Cdd:TIGR02169  858 NLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEaqiEKKRKRLSELKAKLEALEEELSEIE 937

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2027 KFLDEQAIDREHERD--VFQQEIQKLEHQLKAVPRIQPVSEHQAREVEQLTNHLKEKTDRcsellLSKEqlQRDIQERNE 2104
Cdd:TIGR02169  938 DPKGEDEEIPEEELSleDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAK-----LEEE--RKAILERIE 1010


                   ....*
gi 1039770159 2105 EIEKL 2109
Cdd:TIGR02169 1011 EYEKK 1015
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1972-2440 8.44e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.43  E-value: 8.44e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1972 AEKVRGDLQKQVKALEIDV----------EEQVSRFIELEQEKNAELTDLRQQSQALEKQLEKMRKfLDEQAIDREHERD 2041
Cdd:PRK02224   197 EEKEEKDLHERLNGLESELaeldeeieryEEQREQARETRDEADEVLEEHEERREELETLEAEIED-LRETIAETERERE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2042 VFQQEIQKLEHQL----KAVPRIQPVSEHQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELE 2117
Cdd:PRK02224   276 ELAEEVRDLRERLeeleEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLE 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2118 QAllasaepfpkvEDQKRSGAVEADPEL-SLEVQLQVERDATDRKQKEITNLEEQ----------LEQFREELENKNDEV 2186
Cdd:PRK02224   356 ER-----------AEELREEAAELESELeEAREAVEDRREEIEELEEEIEELRERfgdapvdlgnAEDFLEELREERDEL 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2187 QELLMQLEIQRKESTTRLQELQQ---------------ENRLFKVIEEQKEQIQDLETQIERLMSERE--HEKKQREEEV 2249
Cdd:PRK02224   425 REREAELEATLRTARERVEEAEAlleagkcpecgqpveGSPHVETIEEDRERVEELEAELEDLEEEVEevEERLERAEDL 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2250 EQLTGVVEKLQQEVVSTEQQREGAR-TLPEDEE---SFKHQLDKVTAEKLVLEQQVETTNQVMTHMNNVLKEINFKMDQI 2325
Cdd:PRK02224   505 VEAEDRIERLEERREDLEELIAERReTIEEKREraeELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAEL 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2326 TQSLCNLNKECASNEELPSLPKEsvhmtvhelgsdnlqpedapAQDVTKPLEKQTSLTRLQKSPEASRTQEIESLASSV- 2404
Cdd:PRK02224   585 KERIESLERIRTLLAAIADAEDE--------------------IERLREKREALAELNDERRERLAEKRERKRELEAEFd 644

                          490       500       510
                   ....*....|....*....|....*....|....*.
gi 1039770159 2405 GAKDVELTQCREQTETIQEQAQSETDRLQKKLTDLQ 2440
Cdd:PRK02224   645 EARIEEAREDKERAEEYLEQVEEKLDELREERDDLQ 680
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2147-2306 1.19e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.94  E-value: 1.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2147 LEVQLQVERDATDRKQKEITNLEEQLEQFREELENKNDEVQEL---LMQLEIQRKESTTRLQELQQE-NRLFKVIEEQKE 2222
Cdd:COG1196    251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELlaeLARLEQDIARLEERRRELEERlEELEEELAELEE 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2223 QIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQREGARTLPEDEESFKHQLDKVTAEKLVLEQQVE 2302
Cdd:COG1196    331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE 410


                   ....
gi 1039770159 2303 TTNQ 2306
Cdd:COG1196    411 ALLE 414
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2091-2302 1.28e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.00  E-value: 1.28e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2091 SKEQLQRDIQERNEEIEKLECRVRELEQAllasaepfpkvedqkrsgaveadpELSLEVQLQVERDATDRKQKEITNLEE 2170
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKE------------------------EKALLKQLAALERRIAALARRIRALEQ 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2171 QLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENR----------------------LFKVIEEQKEQIQDLE 2228
Cdd:COG4942     77 ELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRqpplalllspedfldavrrlqyLKYLAPARREQAEELR 156

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039770159 2229 TQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQREGARTLPEDEESFKHQLDKVTAEKLVLEQQVE 2302
Cdd:COG4942    157 ADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA 230
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1800-2450 1.38e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.74  E-value: 1.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1800 EELMLNISSRLQAAVEKLLEAISETNTQLEHAKVTQTELMRESFRQKQEATESLHCLEELRERLQEESRAREQLAEELNK 1879
Cdd:pfam15921  270 EQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEK 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1880 -----------AESVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLC---MNNRLQELESDQ-------RRVEEERQLLCR 1938
Cdd:pfam15921  350 qlvlanselteARTERDQFSQESGNLDDQLQKLLADLHKREKELSLekeQNKRLWDRDTGNsitidhlRRELDDRNMEVQ 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1939 QREA----MRAEA-GPVEQQF--LQETEKLMKEKLEVQCQAEKVRGDLQKQVKALEI------DVEEQVSRFIELEQEK- 2004
Cdd:pfam15921  430 RLEAllkaMKSECqGQMERQMaaIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAkkmtleSSERTVSDLTASLQEKe 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2005 ------NAELTDLRQQSQALEKQLEKMRKfldeqaiDREHERDVfQQEIQKLEHQLKAVPRIQPVSEHQareVEQLTNHL 2078
Cdd:pfam15921  510 raieatNAEITKLRSRVDLKLQELQHLKN-------EGDHLRNV-QTECEALKLQMAEKDKVIEILRQQ---IENMTQLV 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2079 KEKTDRCSELLLSKEQLQRDIQERNEEIEKL-------ECRVRELEQALlasaepfPKVEDQKRSGAVEADPELSLEVQL 2151
Cdd:pfam15921  579 GQHGRTAGAMQVEKAQLEKEINDRRLELQEFkilkdkkDAKIRELEARV-------SDLELEKVKLVNAGSERLRAVKDI 651

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2152 QVERDATDRKQK----EITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENR--------------- 2212
Cdd:pfam15921  652 KQERDQLLNEVKtsrnELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKsmegsdghamkvamg 731

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2213 LFKVIEEQKEQIQDLETQI---ERLMSEREHEKKQREEE----VEQLTGVVEKLQQEVVSTEQQREGARTLPEDEESFKH 2285
Cdd:pfam15921  732 MQKQITAKRGQIDALQSKIqflEEAMTNANKEKHFLKEEknklSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEV 811

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2286 QLDKVT-----AEKLVLEQQVETTNQVMTHMNNVlKEIN----FKMDQITQSLCNLNKECASNEELPSLPKESVHMTVHE 2356
Cdd:pfam15921  812 ALDKASlqfaeCQDIIQRQEQESVRLKLQHTLDV-KELQgpgyTSNSSMKPRLLQPASFTRTHSNVPSSQSTASFLSHHS 890

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2357 LGSDNLQPEdaPAQDVTKPLEKQTSLTRLQKSPEASRTQEiESLASSVGAKDVELTQCREQTETIQEQAQSETDRLQKKL 2436
Cdd:pfam15921  891 RKTNALKED--PTRDLKQLLQELRSVINEEPTVQLSKAED-KGRAPSLGALDDRVRDCIIESSLRSDICHSSSNSLQTEG 967

                          730
                   ....*....|....
gi 1039770159 2437 TDLQRSLEKFAAAL 2450
Cdd:pfam15921  968 SKSSETCSREPVLL 981
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 130-748 1.67e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.35  E-value: 1.67e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  130 SSSEQGAQSSQTCLQMVEKELAEKQHDIEELTQELEEMRASFGTEGLKQLQEFEAAIKQRDGIITQLTANLQQARREKDd 209
Cdd:pfam15921  288 SSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERD- 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  210 tmveflELTEQSQKLQIQFQHLQANetlqnstLSRTATDLLQAKRQiftqqqqlqdyQKKEEDLQAQISFLQEKLRafem 289
Cdd:pfam15921  367 ------QFSQESGNLDDQLQKLLAD-------LHKREKELSLEKEQ-----------NKRLWDRDTGNSITIDHLR---- 418

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  290 ekdRKIENLNAkEIQEKQALIDELNTRV---VEEEKKTVELKN----KVTTADELLGGLHEQLTQRNQEIQSLKLELGNS 362
Cdd:pfam15921  419 ---RELDDRNM-EVQRLEALLKAMKSECqgqMERQMAAIQGKNesleKVSSLTAQLESTKEMLRKVVEELTAKKMTLESS 494

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  363 QQNERKCSEEIKELMRTVEELQKrnlkdswlETSAVR-RVEQETQrKLSHLQAELDEMYGKQI------VQMKQ-----E 430
Cdd:pfam15921  495 ERTVSDLTASLQEKERAIEATNA--------EITKLRsRVDLKLQ-ELQHLKNEGDHLRNVQTecealkLQMAEkdkviE 565

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  431 LINQHMSQIEELKSQHKRementlksdTNAAISKEQVNLmNAAINELNVRLQETHAQKEELKGELgvvlgekSALQSQSN 510
Cdd:pfam15921  566 ILRQQIENMTQLVGQHGR---------TAGAMQVEKAQL-EKEINDRRLELQEFKILKDKKDAKI-------RELEARVS 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  511 DL-LEEVRFLR---EQVQKARQTIAEQENRLSEARKSLSTVEDLKAEivaasesrkelelkHEAEITNYKIKLEMLEKEK 586
Cdd:pfam15921  629 DLeLEKVKLVNagsERLRAVKDIKQERDQLLNEVKTSRNELNSLSED--------------YEVLKRNFRNKSEEMETTT 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  587 NAvLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEVEHRINIEklkdnlgihyKQQIDGLQNEMNRKMESMQcetdN 666
Cdd:pfam15921  695 NK-LKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAK----------RGQIDALQSKIQFLEEAMT----N 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  667 LITQQNQLILENSKLRDLQECLVNSKseemnlqiNELQKEIEILKQEEKEkgtLEQEVQELQLKTEQLEKQLKEKEDDLQ 746
Cdd:pfam15921  760 ANKEKHFLKEEKNKLSQELSTVATEK--------NKMAGELEVLRSQERR---LKEKVANMEVALDKASLQFAECQDIIQ 828


                   ..
gi 1039770159  747 EK 748
Cdd:pfam15921  829 RQ 830
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1804-2109 1.77e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 54.29  E-value: 1.77e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1804 LNISSRLQAAVEKLLEAISETNTQLEHAKVTQTELMRESFRQKQEATESLHCLEELRErlqeesrareQLAEELNKAESV 1883
Cdd:TIGR02168  735 LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIE----------QLKEELKALREA 804

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1884 IDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEagpvEQQFLQETEKLMK 1963
Cdd:TIGR02168  805 LDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL----IEELESELEALLN 880

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1964 EKLEVQCQAEKVRGDLQKQVKALEiDVEEQVSRFIELEQEKNAELTDLRQQSQALEKQLEKMRKFLDEQAID-------- 2035
Cdd:TIGR02168  881 ERASLEEALALLRSELEELSEELR-ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLtleeaeal 959

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039770159 2036 ---REHERDVFQQEIQKLEHQLKAVPRIQPVSEHQAREVEQLTNHLKEKTDrcsELLLSKEQLQRDIQERNEEIEKL 2109
Cdd:TIGR02168  960 enkIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKE---DLTEAKETLEEAIEEIDREARER 1033
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 534-880 1.94e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.17  E-value: 1.94e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  534 ENRLSEARKSLSTVEDLKAEIvaasesRKELE-LKHEAEITN--YKIKLEMLEKEKNAVLDRMaESQEAELERLRTQLlf 610
Cdd:COG1196    178 ERKLEATEENLERLEDILGEL------ERQLEpLERQAEKAEryRELKEELKELEAELLLLKL-RELEAELEELEAEL-- 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  611 sheEELSKLKEDLEVEHRiNIEKLKDNLgihyKQQIDGLQNEMNRKMESMQCETDNLITQQNQLILENSKLRDLQEclvn 690
Cdd:COG1196    249 ---EELEAELEELEAELA-ELEAELEEL----RLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE---- 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  691 skseemnlQINELQKEIEILKQEekekgtLEQEVQELQLKTEQLEKQ---LKEKEDDLQEKCAQLDAENNILKEEKRVLE 767
Cdd:COG1196    317 --------RLEELEEELAELEEE------LEELEEELEELEEELEEAeeeLEEAEAELAEAEEALLEAEAELAEAEEELE 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  768 DKLKMYSPSEQEERSIAVDPSTSKSADSRWQKEVAMLRKETEDLQQQCLYLNEEIEKQRNTFAFAEKNFEVNYQELQREY 847
Cdd:COG1196    383 ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL 462

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1039770159  848 TCLLKIRDDLEATQTKQALEYESKLRALEEELL 880
Cdd:COG1196    463 ELLAELLEEAALLEAALAELLEELAEAAARLLL 495
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2961-3254 1.95e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 54.29  E-value: 1.95e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2961 QKQSLEMQLELSSLRDRAAELQEQLSSEKMVVAELKSELAQAKlelgttlkaqhkrlKELEAFRSEVKEKTDEIHFLSDT 3040
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQ--------------KELYALANEISRLEQQKQILRER 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3041 LAREQKNSLELQWALEKEKARSGHHEGRE---KEELEDLKFSLEDQKRRNTQLNLLLEQQKQLLNESQQKIESQKMLHdA 3117
Cdd:TIGR02168  311 LANLERQLEELEAQLEELESKLDELAEELaelEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKV-A 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3118 QLSEEQGRNLGLQALLESEQVRIQEMKSTLDKERELYAQLQSREDggqpppalpsedlLKELQKQLEEKHSRIVELLSET 3197
Cdd:TIGR02168  390 QLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE-------------LKELQAELEELEEELEELQEEL 456

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1039770159 3198 EkykldslQTRQQMEKDRQvhqkTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKR 3254
Cdd:TIGR02168  457 E-------RLEEALEELRE----ELEEAEQALDAAERELAQLQARLDSLERLQENLE 502
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
300-755 2.12e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.89  E-value: 2.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  300 AKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLT---QRNQEIQSLKLELGNSQQNERKC------- 369
Cdd:PRK02224   198 EKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEeheERREELETLEAEIEDLRETIAETerereel 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  370 SEEIKELMRTVEELQKRNlkDSWLETSAVRRVEQET-QRKLSHLQAELDEMygkqivqmkQELINQHMSQIEELKSQHKR 448
Cdd:PRK02224   278 AEEVRDLRERLEELEEER--DDLLAEAGLDDADAEAvEARREELEDRDEEL---------RDRLEECRVAAQAHNEEAES 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  449 EMENTLKSDTNAAISKEQVNLMNAAINELNVRLQETHAQKEELKGEL----------GVVLGEksaLQSQSNDLLEEVRF 518
Cdd:PRK02224   347 LREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIeelrerfgdaPVDLGN---AEDFLEELREERDE 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  519 LREQVQKARQTIAEQENRLSEARKSLST---------VEDlkAEIVAASESRKELELKHEAEITNYKIKLEMLEKEKNAV 589
Cdd:PRK02224   424 LREREAELEATLRTARERVEEAEALLEAgkcpecgqpVEG--SPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  590 LDrmAESQEAELERLR------TQLLFSHE----------EELSKLKEDLEVE-----------------HRINIEKLKD 636
Cdd:PRK02224   502 ED--LVEAEDRIERLEerredlEELIAERRetieekreraEELRERAAELEAEaeekreaaaeaeeeaeeAREEVAELNS 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  637 NLGiHYKQQIDGLQN---------EMNRKMESMQCETDNLITQQNQ----LILENSKLRDLQECL--------------- 688
Cdd:PRK02224   580 KLA-ELKERIESLERirtllaaiaDAEDEIERLREKREALAELNDErrerLAEKRERKRELEAEFdearieearedkera 658

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039770159  689 ------VNSKSEEMNLQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEkQLKEKEDDLQEKCAQLDAE 755
Cdd:PRK02224   659 eeyleqVEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRVEALE-ALYDEAEELESMYGDLRAE 730
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1976-2252 2.59e-06

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 53.75  E-value: 2.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1976 RGDLQKQVKALEIDvEEQVSRFIELEQEKNAELTDLRQQSQALEKQ---LEKMRKFLDEQAIDREHERDVFQQEIQKLEH 2052
Cdd:PLN02939    99 RASMQRDEAIAAID-NEQQTNSKDGEQLSDFQLEDLVGMIQNAEKNillLNQARLQALEDLEKILTEKEALQGKINILEM 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2053 QL-KAVPRIQPVSEHQAR------EVEQLTNHLKEK--TDRCSELLLSKE---------QLQRDIQERNEEI-------- 2106
Cdd:PLN02939   178 RLsETDARIKLAAQEKIHveileeQLEKLRNELLIRgaTEGLCVHSLSKEldvlkeenmLLKDDIQFLKAELievaetee 257

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2107 -----EK----LECRVRELEQALLASAEPFPKVEDQKrsgaVEADPELSLEVQLQVERdATDRKQKEITNLEEQleqfrE 2177
Cdd:PLN02939   258 rvfklEKerslLDASLRELESKFIVAQEDVSKLSPLQ----YDCWWEKVENLQDLLDR-ATNQVEKAALVLDQN-----Q 327

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2178 ELENKNDEVQELLMQLEIQrKESTTRLQELQQ-----ENRLFKVIEEQKEQIQDLETQIERLMS-----EREHEKKQREE 2247
Cdd:PLN02939   328 DLRDKVDKLEASLKEANVS-KFSSYKVELLQQklkllEERLQASDHEIHSYIQLYQESIKEFQDtlsklKEESKKRSLEH 406


                   ....*
gi 1039770159 2248 EVEQL 2252
Cdd:PLN02939   407 PADDM 411
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1918-2445 2.85e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.53  E-value: 2.85e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1918 RLQELESDQRRVEEERQLLCRQREAMRAEAGPVE--QQFLQETEKLMKEKLEVQCQAEKVRGDLQKQVKALEIDVEEQVS 1995
Cdd:PRK03918   156 GLDDYENAYKNLGEVIKEIKRRIERLEKFIKRTEniEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1996 RFIELEqEKNAELTDLRQQSQALEKQLEKMRKFLDEQaidreherdvfQQEIQKLEHQLKAVPRIQPVSEhQAREVEQLT 2075
Cdd:PRK03918   236 LKEEIE-ELEKELESLEGSKRKLEEKIRELEERIEEL-----------KKEIEELEEKVKELKELKEKAE-EYIKLSEFY 302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2076 NHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQALlasaepfpkVEDQKRSGAVEADPELSLEVQLQVER 2155
Cdd:PRK03918   303 EEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKL---------KELEKRLEELEERHELYEEAKAKKEE 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2156 daTDRKQKEITNLE-EQLEQFREELENKNDEVQEllmqleiQRKESTTRLQELQQEnrlfkvIEEQKEQIQDLETQIERL 2234
Cdd:PRK03918   374 --LERLKKRLTGLTpEKLEKELEELEKAKEEIEE-------EISKITARIGELKKE------IKELKKAIEELKKAKGKC 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2235 -MSEREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQREGARTLPEDEESFKHQLDKVTAEKLVLEQqvettnqvmthmnn 2313
Cdd:PRK03918   439 pVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQ-------------- 504

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2314 vLKEINFKMDQItqslcNLNKECASNEELPSLPKESVhmtvhELGSDNLQPEDAPAQdvTKPLEKQTSLTRLQKSPEASR 2393
Cdd:PRK03918   505 -LKELEEKLKKY-----NLEELEKKAEEYEKLKEKLI-----KLKGEIKSLKKELEK--LEELKKKLAELEKKLDELEEE 571

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039770159 2394 TQEIESLASSVGAKDVEltqcrEQTETIQE------------QAQSETDRLQKKLTDLQRSLEK 2445
Cdd:PRK03918   572 LAELLKELEELGFESVE-----ELEERLKElepfyneylelkDAEKELEREEKELKKLEEELDK 630
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2963-3252 3.07e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.53  E-value: 3.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2963 QSLEMQLELSSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELGTTLKAQHKRLKELEAFRSEVKEKTDEIHFLSDTLA 3042
Cdd:TIGR02169  675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIE 754

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3043 rEQKNSLElqwALEKEKARSGHHEGREKEELEDLKFSLEDQKRRNtqlnllLEQQKQLLNESQQKIESQKMLHDAQLSEE 3122
Cdd:TIGR02169  755 -NVKSELK---ELEARIEELEEDLHKLEEALNDLEARLSHSRIPE------IQAELSKLEEEVSRIEARLREIEQKLNRL 824

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3123 QGRNLGLQALLESEQVRIQEMKSTLDKERELYAQLQSRedggqpppalpsedlLKELQKQLEEKHSRIVELLSETEKYKL 3202
Cdd:TIGR02169  825 TLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGK---------------KEELEEELEELEAALRDLESRLGDLKK 889

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3203 DslqtRQQMEKDRQVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQE 3252
Cdd:TIGR02169  890 E----RDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSE 935
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 236-879 3.31e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 53.26  E-value: 3.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  236 TLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAfEMEKDRKIENLNAKEIQEKQALID---E 312
Cdd:pfam01576    1 TRQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQA-ETELCAEAEEMRARLAARKQELEEilhE 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  313 LNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEIKELMRTVEELQKRnlkdsw 392
Cdd:pfam01576   80 LESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKE------ 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  393 letsavRRVEQETQRKLSHLQAELDEMygkqiVQMKQELINQHMSQIEELKSQHKREMENTLKSDTNAAISKEQVNLMNA 472
Cdd:pfam01576  154 ------RKLLEERISEFTSNLAEEEEK-----AKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQE 222

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  473 AINELNVRLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKARQTIAE---QENRLSEARKSLS-TVE 548
Cdd:pfam01576  223 QIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESeraARNKAEKQRRDLGeELE 302

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  549 DLKAEI---VAASESRKELELKHEAEITNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQL-------------LFSH 612
Cdd:pfam01576  303 ALKTELedtLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLeqakrnkanlekaKQAL 382

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  613 EEELSKLKEDL--------EVEHRINIEKLKDNLGIHYKQQIDGLQNEMNRKMESMQCETDNLITQQNQLILENSKLrdl 684
Cdd:pfam01576  383 ESENAELQAELrtlqqakqDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKL--- 459

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  685 qeclvnskSEEMNLQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAENNILKEEKR 764
Cdd:pfam01576  460 --------SKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKK 531

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  765 VLEDKLKMYSPSEQEERSIAVDPSTSKSADSRWQKEVAMLRKETEDLQQQCLYLNEEIEKQRNTFAFAEKNFEVNYQELQ 844
Cdd:pfam01576  532 KLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLA 611

                          650       660       670
                   ....*....|....*....|....*....|....*...
gi 1039770159  845 REYTCLLKI---RDDLEATQTKQALEYESKLRALEEEL 879
Cdd:pfam01576  612 EEKAISARYaeeRDRAEAEAREKETRALSLARALEEAL 649
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1811-2258 4.64e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 52.85  E-value: 4.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1811 QAAVEKLLEAISETNTQLEHAKVTQTELmRESFRQKQEATESLHCLEELRERLQEESRAREQLAEELNKAESVIDGYSDE 1890
Cdd:COG4717     87 EEEYAELQEELEELEEELEELEAELEEL-REELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEEL 165

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1891 KTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEAGPVEQQFLQETEKLMKEKLEVQC 1970
Cdd:COG4717    166 EELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERL 245

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1971 QAEKVRGDLQKQVKALEIDVEEQVSRFIELeqeknAELTDLRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQ-EIQK 2049
Cdd:COG4717    246 KEARLLLLIAAALLALLGLGGSLLSLILTI-----AGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEElEEEE 320

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2050 LEHQLKAVPRIQPVSEHQAREVEQLTNHLKEKTDRCSELllskeQLQRDIQERNEEIEKLecrvreLEQALLASAEPFPK 2129
Cdd:COG4717    321 LEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEL-----EEELQLEELEQEIAAL------LAEAGVEDEEELRA 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2130 VEDQKRSGAVEADPELSLEVQLQVERDATDRKQKEIT--NLEEQLEQFREELENKNDEVQELLMQL-----EIQRKESTT 2202
Cdd:COG4717    390 ALEQAEEYQELKEELEELEEQLEELLGELEELLEALDeeELEEELEELEEELEELEEELEELREELaeleaELEQLEEDG 469

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1039770159 2203 RLQELQQEnrlfkvIEEQKEQIQDLETQIERLMSEREH-EKKQREEEVEQLTGVVEK 2258
Cdd:COG4717    470 ELAELLQE------LEELKAELRELAEEWAALKLALELlEEAREEYREERLPPVLER 520
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2023-2252 5.15e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 50.69  E-value: 5.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2023 EKMRKFLDEQAIDreherdvfqQEIQKLEHQLKAVPRiqpvsehqarEVEQLTNHLKEKTDRCSELLLSKEQLQRDIQER 2102
Cdd:COG1579      4 EDLRALLDLQELD---------SELDRLEHRLKELPA----------ELAELEDELAALEARLEAAKTELEDLEKEIKRL 64

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2103 NEEIEKLECRVReleqallasaepfpkvEDQKRSGAVeadpelslevqlqverdatdRKQKEITNLEEQLEQFREELENK 2182
Cdd:COG1579     65 ELEIEEVEARIK----------------KYEEQLGNV--------------------RNNKEYEALQKEIESLKRRISDL 108

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2183 NDEVQELLMQLEIQRKEsttrLQELQQEnrLFKVIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQL 2252
Cdd:COG1579    109 EDEILELMERIEELEEE----LAELEAE--LAELEAELEEKKAELDEELAELEAELEELEAEREELAAKI 172
PRK12704 PRK12704
phosphodiesterase; Provisional
 2092-2270 5.66e-06

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 52.09  E-value: 5.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2092 KEQLQRDIQERNEEIEKLECRVRELEQALlasaepfpkvedqkrsgaveadpelslevqlqverdatDRKQKEITNLEEQ 2171
Cdd:PRK12704    70 RNEFEKELRERRNELQKLEKRLLQKEENL--------------------------------------DRKLELLEKREEE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2172 LEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENRlfkviEEQKEQIqdletqIERLMSEREHEK----KQREE 2247
Cdd:PRK12704   112 LEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTA-----EEAKEIL------LEKVEEEARHEAavliKEIEE 180

                          170       180
                   ....*....|....*....|...
gi 1039770159 2248 EVEQLtgvVEKLQQEVVSTEQQR 2270
Cdd:PRK12704   181 EAKEE---ADKKAKEILAQAIQR 200
PTZ00121 PTZ00121
MAEBL; Provisional
 2970-3284 7.33e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 7.33e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2970 ELSSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELGTTLKAQHKRLKELEAFRSEVKEKTDEIhflsDTLAREQKNSL 3049
Cdd:PTZ00121  1346 EAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADEL----KKAAAAKKKAD 1421

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3050 EL-QWALEKEKARSGHHEGREKEELEDLKFSLEDQKR-----------RNTQLNLLLEQQKQLLNESQQKIESQKMLHDA 3117
Cdd:PTZ00121  1422 EAkKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKaeeakkkaeeaKKADEAKKKAEEAKKADEAKKKAEEAKKKADE 1501

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3118 QLSEEQGRNLGLQALLESEQVRIQEMKSTLDKERElyAQLQSREDGGQPPPALPSEDLLK-ELQKQLEEKHS-------- 3188
Cdd:PTZ00121  1502 AKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKA--DEAKKAEEKKKADELKKAEELKKaEEKKKAEEAKKaeedknma 1579

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3189 -RIVELLSETEKYKLDSLQTRQQMEKDRQVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQQVYKLDLEGKRL 3267
Cdd:PTZ00121  1580 lRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEEN 1659

                          330
                   ....*....|....*..
gi 1039770159 3268 QGLMQEFQKQELEPEEK 3284
Cdd:PTZ00121  1660 KIKAAEEAKKAEEDKKK 1676
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 136-354 7.66e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 7.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  136 AQSSQTCLQMVEKELAEKQHDIEELTQELEEMRASFgTEGLKQLQEFEAAIKQRDGIITQLTANLQQARREKDDTMVEFL 215
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEE-KALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  216 ELT----EQSQKLQIQFQHLQANETLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEMEK 291
Cdd:COG4942     94 ELRaeleAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039770159  292 DRKIENLN---------AKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQS 354
Cdd:COG4942    174 AELEALLAeleeeraalEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 300-540 1.04e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 1.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  300 AKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEIKELMRT 379
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  380 VEELQKRnlkdswLETSAVRRVEQETQRKLSHL-------QAELDEMYGKQIVQMKQELINQHMSQIEELKSQhkremen 452
Cdd:COG4942     99 LEAQKEE------LAELLRALYRLGRQPPLALLlspedflDAVRRLQYLKYLAPARREQAEELRADLAELAAL------- 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  453 tlksdtNAAISKEQVNLmNAAINELNVRLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKARQTIAE 532
Cdd:COG4942    166 ------RAELEAERAEL-EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238


                   ....*...
gi 1039770159  533 QENRLSEA 540
Cdd:COG4942    239 AAERTPAA 246
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 483-782 1.07e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 51.66  E-value: 1.07e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  483 ETHAQKEELKGELGVVLGEKSALQSQSNDLLEEV---RFLREQVQKARQTiaEQENRLSEARKSLSTVEDLKAEIVAASE 559
Cdd:pfam17380  263 QTMTENEFLNQLLHIVQHQKAVSERQQQEKFEKMeqeRLRQEKEEKAREV--ERRRKLEEAEKARQAEMDRQAAIYAEQE 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  560 sRKELELKHEAE---ITNYKIKLEMLEKEKNAV-LDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEVEHRINIEKLK 635
Cdd:pfam17380  341 -RMAMERERELErirQEERKRELERIRQEEIAMeISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQK 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  636 DNLGIHYKQQIDGLQNEMNRKMESMQCETDNLITQQNQLILENSKLRDLQECLVNSKSEEMNLQINELQKEIEILKQEEK 715
Cdd:pfam17380  420 VEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEK 499

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039770159  716 EKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAENNILK----EEKRVLEDKLKMYSpseqEERS 782
Cdd:pfam17380  500 ELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKqqemEERRRIQEQMRKAT----EERS 566
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2147-2306 1.17e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.48  E-value: 1.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2147 LEVQLQVERDATDRKQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRKEsttRLQELQQENRLFKVIEEQKEQIQD 2226
Cdd:COG1196    237 LEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAE---EYELLAELARLEQDIARLEERRRE 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2227 LETQIERLMSEREHEKKQREEEVEQLtgvvEKLQQEVVSTEQQREGARtlpEDEESFKHQLDKVTAEKLVLEQQVETTNQ 2306
Cdd:COG1196    314 LEERLEELEEELAELEEELEELEEEL----EELEEELEEAEEELEEAE---AELAEAEEALLEAEAELAEAEEELEELAE 386
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 302-963 1.25e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 51.59  E-value: 1.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  302 EIQEKQALIDELNTRVveeeKKTVELK----NKVTTADELLG----GLHEQLTQRNQEIQSLKLELgnSQQNERKCSEEI 373
Cdd:TIGR01612  604 ELKEKIKNISDKNEYI----KKAIDLKkiieNNNAYIDELAKispyQVPEHLKNKDKIYSTIKSEL--SKIYEDDIDALY 677

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  374 KELMRTVEElqkrnlkdswletSAVRRVEQETqrKLSHLQAELDEMYGKqIVQMKQELINQHMSQIEELKSQhkrement 453
Cdd:TIGR01612  678 NELSSIVKE-------------NAIDNTEDKA--KLDDLKSKIDKEYDK-IQNMETATVELHLSNIENKKNE-------- 733

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  454 lKSDTNAAISKEQVNLMNaaiNELNVRLQETHAQKEEL----------KGELGVVLGEKSALQSQSNDLL-------EEV 516
Cdd:TIGR01612  734 -LLDIIVEIKKHIHGEIN---KDLNKILEDFKNKEKELsnkindyakeKDELNKYKSKISEIKNHYNDQInidnikdEDA 809

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  517 RFLREQVQKARQTIAEQENrlsEARKSLSTVEDLKAEIVAASESRKELELKHEAEITNYKIKL-EMLEKEKNAVLDRMAE 595
Cdd:TIGR01612  810 KQNYDKSKEYIKTISIKED---EIFKIINEMKFMKDDFLNKVDKFINFENNCKEKIDSEHEQFaELTNKIKAEISDDKLN 886

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  596 SQEAEL---ERLRTQLLFSHEEELSKLKEDLEVEHRINI-EKLKDNL-GIHYKQQIdgLQNEMNRKMESMQceTDNLITQ 670
Cdd:TIGR01612  887 DYEKKFndsKSLINEINKSIEEEYQNINTLKKVDEYIKIcENTKESIeKFHNKQNI--LKEILNKNIDTIK--ESNLIEK 962

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  671 QNQLILENS---KLRDLQECLVNSKSEEMNLQINELQKEIEILKQ--------------EEKEKGT--LEQEVQELQLKT 731
Cdd:TIGR01612  963 SYKDKFDNTlidKINELDKAFKDASLNDYEAKNNELIKYFNDLKAnlgknkenmlyhqfDEKEKATndIEQKIEDANKNI 1042

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  732 EQLEKQLKEKEDDLQEKCAQLDAEN------NILKEEK------RVLEDKLKMYSPSEqeersiavdpsTSKSADSRWQK 799
Cdd:TIGR01612 1043 PNIEIAIHTSIYNIIDEIEKEIGKNiellnkEILEEAEinitnfNEIKEKLKHYNFDD-----------FGKEENIKYAD 1111

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  800 EVAMLRKETEDLQQQclylneeIEKQRNTFAFAEKNFEVNYQELQREYTCLLKIRDDLEATQTKQALEyesklraleeel 879
Cdd:TIGR01612 1112 EINKIKDDIKNLDQK-------IDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKAISNDDPEEIE------------ 1172

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  880 lSKRGNPAAPKGKSSGIFPSETLEIGEV--VEKDTTElmekLEVTKREKLELSEKVSGL-----SEQLKQTHCTINSLSA 952
Cdd:TIGR01612 1173 -KKIENIVTKIDKKKNIYDEIKKLLNEIaeIEKDKTS----LEEVKGINLSYGKNLGKLflekiDEEKKKSEHMIKAMEA 1247

                          730
                   ....*....|.
gi 1039770159  953 EVRALKQEKEQ 963
Cdd:TIGR01612 1248 YIEDLDEIKEK 1258
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 2073-2324 1.25e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 51.28  E-value: 1.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2073 QLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECR--VRELEQALLASAEPFPKVEDQKRSGAVEADPELSLEVQ 2150
Cdd:pfam17380  276 HIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRrkLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQ 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2151 LQVERDATDRKQKEIT---NLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENRLFKVIEEQKEQIQdl 2227
Cdd:pfam17380  356 EERKRELERIRQEEIAmeiSRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEAR-- 433

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2228 ETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEvvstEQQREGARTLPEDEESFKHQLDKVtaEKLVLEQQVETTNQV 2307
Cdd:pfam17380  434 QREVRRLEEERAREMERVRLEEQERQQQVERLRQQ----EEERKRKKLELEKEKRDRKRAEEQ--RRKILEKELEERKQA 507

                          250
                   ....*....|....*..
gi 1039770159 2308 MTHMNNVLKEINFKMDQ 2324
Cdd:pfam17380  508 MIEEERKRKLLEKEMEE 524
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2067-2246 1.27e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.31  E-value: 1.27e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2067 QAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQALlasaEPFPKVEDQKrsgavEADPELS 2146
Cdd:COG4717     72 ELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLL----QLLPLYQELE-----ALEAELA 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2147 levQLQVERDATDRKQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQR----KESTTRLQELQQE-NRLFKVIEEQK 2221
Cdd:COG4717    143 ---ELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATeeelQDLAEELEELQQRlAELEEELEEAQ 219

                          170       180
                   ....*....|....*....|....*
gi 1039770159 2222 EQIQDLETQIERLMSEREHEKKQRE 2246
Cdd:COG4717    220 EELEELEEELEQLENELEAAALEER 244
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2171-2461 1.36e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.48  E-value: 1.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2171 QLEQFREELENKNDEVQELlmqlEIQRKESTTRLQELQQEnrlfkvIEEQKEQIQDLETQIERLMSEREHEKKQREEEVE 2250
Cdd:COG1196    233 KLRELEAELEELEAELEEL----EAELEELEAELAELEAE------LEELRLELEELELELEEAQAEEYELLAELARLEQ 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2251 QLTGVVEKLQQEVVSTEQQREGARTLPEDEESFKHQLDKVTAEKLVLEQQVETTNQVMTHMNNVLKEINFKMDQITQSLC 2330
Cdd:COG1196    303 DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2331 NLNKECASNEElpslpkesvhmTVHELGSDNLQPEDAPAQDVTKPLEKQTSLTRLQKSPEASRTQEIESLASSVGAKDVE 2410
Cdd:COG1196    383 ELAEELLEALR-----------AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039770159 2411 LTQCREQTETIQ--EQAQSETDRLQKKLTDLQRSLEKFAAALVSQVQMEAAQE 2461
Cdd:COG1196    452 AELEEEEEALLEllAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2886-3284 1.43e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.22  E-value: 1.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2886 STRDVDGLLNSLEQRIQEQGIEYHTAMDCLQKADR-----RSLLAEIEDLRAQINGGKMTLEREQGTEKSSQELLdcSMQ 2960
Cdd:PRK03918   187 RTENIEELIKEKEKELEEVLREINEISSELPELREeleklEKEVKELEELKEEIEELEKELESLEGSKRKLEEKI--REL 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2961 QKQSLEMQLELSSLRDRAAELQEQLSSEKMVVA------ELKSELAQAKLELGT---TLKAQHKRLKELEAFRSEVKEKT 3031
Cdd:PRK03918   265 EERIEELKKEIEELEEKVKELKELKEKAEEYIKlsefyeEYLDELREIEKRLSRleeEINGIEERIKELEEKEERLEELK 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3032 DEIHFLSDTLAREQKNSLELQWALEKEKARSGHHEGREKEELEDLKFSLEDQKRRNTQLNLLLEQQKQLLNESQQKIESQ 3111
Cdd:PRK03918   345 KKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKEL 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3112 KM-------------LHDAQLSEEQGRNLGLQALLESEQVRiQEMKSTLDKERELYAQLQSREDGGQPPPALPSEDLLKE 3178
Cdd:PRK03918   425 KKaieelkkakgkcpVCGRELTEEHRKELLEEYTAELKRIE-KELKEIEEKERKLRKELRELEKVLKKESELIKLKELAE 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3179 LQKQLEEKHSRIV--ELLSETEKY-----KLDSLQTRQQMEKDRQVHQKTLQTEQEANtqgQKKMQELQSKVEELQRQLQ 3251
Cdd:PRK03918   504 QLKELEEKLKKYNleELEKKAEEYeklkeKLIKLKGEIKSLKKELEKLEELKKKLAEL---EKKLDELEEELAELLKELE 580

                          410       420       430
                   ....*....|....*....|....*....|....*....
gi 1039770159 3252 EKR-QQVYKLDLEGKRLQGLMQEF-----QKQELEPEEK 3284
Cdd:PRK03918   581 ELGfESVEELEERLKELEPFYNEYlelkdAEKELEREEK 619
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1881-2468 1.53e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.27  E-value: 1.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1881 ESVIDGYSDEKTLFERQIQEKTDIIE----HLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEAGPVEQQFlq 1956
Cdd:pfam15921   77 ERVLEEYSHQVKDLQRRLNESNELHEkqkfYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL-- 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1957 ETEKLMKEKL--EVQCQAEKVR-------GDLQkQVKALEIDVEEQVSRFI-------------------ELEQEKNAEL 2008
Cdd:pfam15921  155 EAAKCLKEDMleDSNTQIEQLRkmmlsheGVLQ-EIRSILVDFEEASGKKIyehdsmstmhfrslgsaisKILRELDTEI 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2009 TDLRQQSQALEKQLEKMR-KFLDEQAIDREHERDVFQQEIQKLEHQLKAVPRIQPVSEHQAREV--------EQLTNHLK 2079
Cdd:pfam15921  234 SYLKGRIFPVEDQLEALKsESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIqsqleiiqEQARNQNS 313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2080 EKTDRCSELLLSKEQLQRDIQERNEEIEKlecRVRELEQALLASAEPFPKVEDQKRSGAVEADpelSLEVQLQVERDATD 2159
Cdd:pfam15921  314 MYMRQLSDLESTVSQLRSELREAKRMYED---KIEELEKQLVLANSELTEARTERDQFSQESG---NLDDQLQKLLADLH 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2160 RKQKEITNLEEQ--------------LEQFREELENKNDEVQELLMQLEIQRKESTTRLQE----LQQENR--------- 2212
Cdd:pfam15921  388 KREKELSLEKEQnkrlwdrdtgnsitIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERqmaaIQGKNEslekvsslt 467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2213 ---------LFKVIEEQKEQIQDLETQiERLMSEREHEKKQREEEVEQLTGVVEKLQ-------QEVVSTEQQREGARTL 2276
Cdd:pfam15921  468 aqlestkemLRKVVEELTAKKMTLESS-ERTVSDLTASLQEKERAIEATNAEITKLRsrvdlklQELQHLKNEGDHLRNV 546

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2277 PEDEESFKHQLDKVTAEKLVLEQQVETTNQ-----------VMTHMNNVLKEINFKMDQITQSLCNLNKECASNEELPS- 2344
Cdd:pfam15921  547 QTECEALKLQMAEKDKVIEILRQQIENMTQlvgqhgrtagaMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEAr 626

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2345 ---LPKESVHMTvhELGSDNLQpedaPAQDVTKPLEKQTSLTRLQKSPEASRTQEIESLASSVGAKDVELTQCREQTETI 2421
Cdd:pfam15921  627 vsdLELEKVKLV--NAGSERLR----AVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQ 700

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1039770159 2422 QEQAQSETDRLQKKLTDLQRS---LEKFAAALVSQV-----QMEAAQEYVPFHQE 2468
Cdd:pfam15921  701 LKSAQSELEQTRNTLKSMEGSdghAMKVAMGMQKQItakrgQIDALQSKIQFLEE 755
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
464-660 1.60e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 1.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  464 KEQVNLMNAAINELNVRLQETHAQKEELKGELGVVLGEKSALQSqsndlLEEVRFLREQVQKARQTIAEQENRLSEARKS 543
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQR-----LAEYSWDEIDVASAEREIAELEAELERLDAS 683

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  544 LSTVEDLKAEIVAASESRKELelkhEAEITNYKIKLEMLEKEknavLDRMAESQEAELERLRTQLLFSHEEELSKLKEDL 623
Cdd:COG4913    684 SDDLAALEEQLEELEAELEEL----EEELDELKGEIGRLEKE----LEQAEEELDELQDRLEAAEDLARLELRALLEERF 755

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1039770159  624 EvehRINIEKLKDNLGIHYKQQIDGLQNEMNRKMESM 660
Cdd:COG4913    756 A---AALGDAVERELRENLEERIDALRARLNRAEEEL 789
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 486-814 2.28e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.84  E-value: 2.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  486 AQKEELKGELGVV---LGEKSALQSQSNDLLEEVRFLREQVQKARQTIAEQENRlsEARKSLSTVEDLKAEIVAASESRK 562
Cdd:TIGR02169  170 RKKEKALEELEEVeenIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREY--EGYELLKEKEALERQKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  563 ELElkheAEITNYKIKLEMLEKEKNAVldrmaesqEAELERLRTQLLFSHEEELSKLKEDLEvEHRINIEKLKDNLGIhY 642
Cdd:TIGR02169  248 SLE----EELEKLTEEISELEKRLEEI--------EQLLEELNKKIKDLGEEEQLRVKEKIG-ELEAEIASLERSIAE-K 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  643 KQQIDGLQNEMnRKMESMQCETDNLITQQNQLILENSKLRDLQECLVNSKSEEMNLQINELQKE-------IEILKQEEK 715
Cdd:TIGR02169  314 ERELEDAEERL-AKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVdkefaetRDELKDYRE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  716 EKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAENNILKEEKRVLEDKLKMYSPSEQEERSIAVDPSTSKSADS 795
Cdd:TIGR02169  393 KLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELY 472

                          330
                   ....*....|....*....
gi 1039770159  796 RWQKEVAMLRKETEDLQQQ 814
Cdd:TIGR02169  473 DLKEEYDRVEKELSKLQRE 491
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1971-2261 2.35e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 50.72  E-value: 2.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1971 QAEKVrGDLQKQVKALEIDVEEQVsrfiELEQEKNAELTDLRQQSQALEKQLEKMRKFLD--EQAIDREHERDV-FQQEI 2047
Cdd:COG3096    345 QQEKI-ERYQEDLEELTERLEEQE----EVVEEAAEQLAEAEARLEAAEEEVDSLKSQLAdyQQALDVQQTRAIqYQQAV 419

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2048 QKLE--HQLKAVPRIQP------VSEHQAREvEQLTNHLKEKTDRCSELLLSKEQLQRDIQ---------ERNEEIEK-- 2108
Cdd:COG3096    420 QALEkaRALCGLPDLTPenaedyLAAFRAKE-QQATEEVLELEQKLSVADAARRQFEKAYElvckiagevERSQAWQTar 498

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2109 -LECRVRELeQALLASAEPFpkvedqkrsGAVEADPELSLEVQLQVERDATDRKQK---------EITNLEEQLEQFREE 2178
Cdd:COG3096    499 eLLRRYRSQ-QALAQRLQQL---------RAQLAELEQRLRQQQNAERLLEEFCQRigqqldaaeELEELLAELEAQLEE 568

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2179 LENKNDEVQELLMQLEIQRKESTTRLQELQQE-----------NRLFKVIEEQKEQIQDLETQIERLMsEREHEKKQREE 2247
Cdd:COG3096    569 LEEQAAEAVEQRSELRQQLEQLRARIKELAARapawlaaqdalERLREQSGEALADSQEVTAAMQQLL-EREREATVERD 647

                          330
                   ....*....|....*...
gi 1039770159 2248 EV----EQLTGVVEKLQQ 2261
Cdd:COG3096    648 ELaarkQALESQIERLSQ 665
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1804-2251 2.38e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.56  E-value: 2.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1804 LNISSRLQAAVEKLLEAISETNTQL--EHAKVTQTELMRESFRQKQEATeslhcLEELRERLQEESRAREQLAEELNKAE 1881
Cdd:pfam01576  365 LEQAKRNKANLEKAKQALESENAELqaELRTLQQAKQDSEHKRKKLEGQ-----LQELQARLSESERQRAELAEKLSKLQ 439

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1882 SVIDGYS--------------DEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEA 1947
Cdd:pfam01576  440 SELESVSsllneaegkniklsKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQL 519

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1948 GPVEQQfLQETEKLMKEKLEVQCQAEKVRGDLQKQVKALEIDVEEQVSRFIELEQEKN---AELTDL-------RQQSQA 2017
Cdd:pfam01576  520 STLQAQ-LSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNrlqQELDDLlvdldhqRQLVSN 598

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2018 LEKQLEKMRKFL-DEQAIDREHERDVFQQEIQKLEHQLKAVPriqpvsehQAREVEQLTNHLKEKTDRCSELLLSKEQLQ 2096
Cdd:pfam01576  599 LEKKQKKFDQMLaEEKAISARYAEERDRAEAEAREKETRALS--------LARALEEALEAKEELERTNKQLRAEMEDLV 670

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2097 RDIQERNEEIEKLECRVRELEQALLASAEPFPKVEDQKRsgaVEADPELSLEVQLQVERDATDRkqkEITNLEEQLEQFR 2176
Cdd:pfam01576  671 SSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQ---ATEDAKLRLEVNMQALKAQFER---DLQARDEQGEEKR 744

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2177 EELenkNDEVQELLMQLEIQRKEST----------TRLQELQ-QENRLFKVIEEQKEQIQDLETQIERLMSEREHEKKQR 2245
Cdd:pfam01576  745 RQL---VKQVRELEAELEDERKQRAqavaakkkleLDLKELEaQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASR 821


                   ....*.
gi 1039770159 2246 EEEVEQ 2251
Cdd:pfam01576  822 DEILAQ 827
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1868-2276 2.43e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.15  E-value: 2.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1868 RAREQLAEELNKAESVIDGYS---DEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQL--LCRQREA 1942
Cdd:COG4717     71 KELKELEEELKEAEEKEEEYAelqEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELaeLPERLEE 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1943 MRAEagpveqqfLQETEKLMKEKLEVQCQAEKVRGDLQKQVKALEIDVEEQVSRFIELEQEKNAELTDLRQQSQALEKQL 2022
Cdd:COG4717    151 LEER--------LEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEEL 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2023 EKMRKflDEQAIDREHERDVFQQEIQKLEHQLKAVPRIQPVSEHQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQER 2102
Cdd:COG4717    223 EELEE--ELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASL 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2103 NEEIEKLEC--RVRELEQALLAS-AEPFPKVEDQKRSGAVEADPELSlEVQLQVERDATDRKQKEITNLEEQLEQFREEL 2179
Cdd:COG4717    301 GKEAEELQAlpALEELEEEELEElLAALGLPPDLSPEELLELLDRIE-ELQELLREAEELEEELQLEELEQEIAALLAEA 379

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2180 ENKNDE-VQELLMQLEiQRKESTTRLQELQQENRLFKVIEEQKEQIQDLETQIERLmSEREHEKKQREEEVEQLTGVVEK 2258
Cdd:COG4717    380 GVEDEEeLRAALEQAE-EYQELKEELEELEEQLEELLGELEELLEALDEEELEEEL-EELEEELEELEEELEELREELAE 457

                          410
                   ....*....|....*...
gi 1039770159 2259 LQQEVVSTEQQREGARTL 2276
Cdd:COG4717    458 LEAELEQLEEDGELAELL 475
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
489-641 2.50e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 50.24  E-value: 2.50e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  489 EELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKAR-------QTIAEQENRLsearkslstvEDLKAEIVAASESR 561
Cdd:COG2433    388 KELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEaeveeleAELEEKDERI----------ERLERELSEARSEE 457

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  562 KElELKHEAEITNYKIKLEMLEKEKNAvLDRMAESQEAELERLRTQLLFSHEEELSKLK--EDLEVEHrinIEKLKDNLG 639
Cdd:COG2433    458 RR-EIRKDREISRLDREIERLERELEE-ERERIEELKRKLERLKELWKLEHSGELVPVKvvEKFTKEA---IRRLEEEYG 532


                   ..
gi 1039770159  640 IH 641
Cdd:COG2433    533 LK 534
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 699-878 3.02e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 3.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  699 QINELQKEIE----ILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEDDL---QEKCAQLDAENNILKEEKRVLEDKLK 771
Cdd:COG4942     28 ELEQLQQEIAelekELAALKKEEKALLKQLAALERRIAALARRIRALEQELaalEAELAELEKEIAELRAELEAQKEELA 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  772 -----MYSPSEQEERSIAVDPSTSKSADSRW----------QKEVAMLRKETEDLQQqclyLNEEIEKQRNTFAFAEKNF 836
Cdd:COG4942    108 ellraLYRLGRQPPLALLLSPEDFLDAVRRLqylkylaparREQAEELRADLAELAA----LRAELEAERAELEALLAEL 183

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1039770159  837 EVNYQELQREytclLKIRDDLEATQTKQALEYESKLRALEEE 878
Cdd:COG4942    184 EEERAALEAL----KAERQKLLARLEKELAELAAELAELQQE 221
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 515-774 3.59e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 49.93  E-value: 3.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  515 EVRFLREQVQKARqtIAEQENRLSEARKSLSTVEDLKAEIVAASESRKELELKHEAEItnykikLEMLEKEKNAVLDRMa 594
Cdd:PRK05771    32 HIEDLKEELSNER--LRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEEL------IKDVEEELEKIEKEI- 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  595 ESQEAELERLRTQLlfsheEELSKLKEDLEVEHRINIEkLKDNLGIHYKQQIDGLQNEmnRKMESMQCETDNLitqqNQL 674
Cdd:PRK05771   103 KELEEEISELENEI-----KELEQEIERLEPWGNFDLD-LSLLLGFKYVSVFVGTVPE--DKLEELKLESDVE----NVE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  675 ILENSKLRDLqeCLVNSKSEEMNLQINELqKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDA 754
Cdd:PRK05771   171 YISTDKGYVY--VVVVVLKELSDEVEEEL-KKLGFERLELEEEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLE 247

                          250       260
                   ....*....|....*....|
gi 1039770159  755 ENNILKEEKRVLEDKLKMYS 774
Cdd:PRK05771   248 ELLALYEYLEIELERAEALS 267
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 2960-3284 3.66e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.17  E-value: 3.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2960 QQKQSLEMQLELSSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELGTTLkaqhKRLKELEAFRSEVKEKTDEIhflsd 3039
Cdd:pfam01576  199 EEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAAL----ARLEEETAQKNNALKKIREL----- 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3040 tlareQKNSLELQWALEKEKARSGHHEGREK---EELEDLKFSLEDQKRRNTQLNLLLEQQKQLLNESQQKIESQKMLHD 3116
Cdd:pfam01576  270 -----EAQISELQEDLESERAARNKAEKQRRdlgEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3117 AQLSE-EQGRNLGLQALLES-EQVR-----IQEMKSTLDKER-ELYAQLQSREDGGQpppalPSEDLLKELQKQLEEKHS 3188
Cdd:pfam01576  345 AQLQEmRQKHTQALEELTEQlEQAKrnkanLEKAKQALESENaELQAELRTLQQAKQ-----DSEHKRKKLEGQLQELQA 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3189 RivelLSETEKYKLDSLQTRQQMEKDRQVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQQVYKLDLEGKRLQ 3268
Cdd:pfam01576  420 R----LSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLE 495

                          330
                   ....*....|....*.
gi 1039770159 3269 GLMQEFQKQELEPEEK 3284
Cdd:pfam01576  496 DERNSLQEQLEEEEEA 511
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1920-2327 3.74e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 50.05  E-value: 3.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1920 QELESDQRRVEEERQLLCRQReAMRAEAGPVEQQFLQETEK-------LMKEKLEVQCQAEKVRGDLQKQVKALEIDVEE 1992
Cdd:TIGR00606  635 QDEESDLERLKEEIEKSSKQR-AMLAGATAVYSQFITQLTDenqsccpVCQRVFQTEAELQEFISDLQSKLRLAPDKLKS 713

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1993 QVSRFIELEQE-----------------KNAELTDLRQQSQALEKQLEKMRKFLDEQ------AIDREHERDVFQQE--- 2046
Cdd:TIGR00606  714 TESELKKKEKRrdemlglapgrqsiidlKEKEIPELRNKLQKVNRDIQRLKNDIEEQetllgtIMPEEESAKVCLTDvti 793

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2047 IQKLEHQLKAVPR--IQPVSEHQA----REVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQAL 2120
Cdd:TIGR00606  794 MERFQMELKDVERkiAQQAAKLQGsdldRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEK 873

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2121 LASAEPFpkvedQKRSGAVEADPELSLEVQlqverdATDRKQKEITNLEEQLEQFREELENKNDEVqellmqleIQRKES 2200
Cdd:TIGR00606  874 LQIGTNL-----QRRQQFEEQLVELSTEVQ------SLIREIKDAKEQDSPLETFLEKDQQEKEEL--------ISSKET 934

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2201 TTRLQELQqenrlFKVIEEQKEQIQDLETQIERLMSE-REHEKKQREEEVEQLTGVVEKLQQEvvsTEQQREGARTLPED 2279
Cdd:TIGR00606  935 SNKKAQDK-----VNDIKEKVKNIHGYMKDIENKIQDgKDDYLKQKETELNTVNAQLEECEKH---QEKINEDMRLMRQD 1006

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*...
gi 1039770159 2280 EESfKHQLDKVTAEKLVLEQQVETTNQVMTHMNNVLKEINfkMDQITQ 2327
Cdd:TIGR00606 1007 IDT-QKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMG--QMQVLQ 1051
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 556-755 4.03e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 4.03e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  556 AASESRKELElKHEAEITNYKIKLEMLEKEKNAVLDRMAEsQEAELERLrTQLLFSHEEELSKLKEDLEvEHRINIEKLK 635
Cdd:COG4942     21 AAAEAEAELE-QLQQEIAELEKELAALKKEEKALLKQLAA-LERRIAAL-ARRIRALEQELAALEAELA-ELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  636 DNLGIH---YKQQIDGLQ-----------------NEMNRKMESMQCETDNLITQQNQLILENSKLRDLQEcLVNSKSEE 695
Cdd:COG4942     97 AELEAQkeeLAELLRALYrlgrqpplalllspedfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA-ELEAERAE 175

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  696 MNLQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAE 755
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 643-768 4.46e-05

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 48.48  E-value: 4.46e-05
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159   643 KQQIDGLQNEMNRKMESMQCETDNLITQQNQLileNSKLRDLQECLVNSKSEEMNLQinELQKEIEILKQEE----KEK- 717
Cdd:smart00787  139 MKLLEGLKEGLDENLEGLKEDYKLLMKELELL---NSIKPKLRDRKDALEEELRQLK--QLEDELEDCDPTEldraKEKl 213

                            90       100       110       120       130
                    ....*....|....*....|....*....|....*....|....*....|.
gi 1039770159   718 GTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAENNILKEEKRVLED 768
Cdd:smart00787  214 KKLLQEIMIKVKKLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQ 264
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
502-740 4.53e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 49.63  E-value: 4.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  502 KSALQSQSNDLLEEVRFLREQVQKARQTIAEQENRLSEARKSLSTVeDLKAEIVAASESRKELelkhEAEITNYKIKLEM 581
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLV-DLSEEAKLLLQQLSEL----ESQLAEARAELAE 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  582 LEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEVEhrinIEKLKDNlgiH-----YKQQIDGLQNEMNRK 656
Cdd:COG3206    238 AEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAEL----SARYTPN---HpdviaLRAQIAALRAQLQQE 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  657 MESMqcetdnLITQQNQLILENSKLRDLQEclvnskseemnlQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEK 736
Cdd:COG3206    311 AQRI------LASLEAELEALQAREASLQA------------QLAQLEARLAELPELEAELRRLEREVEVARELYESLLQ 372


                   ....
gi 1039770159  737 QLKE 740
Cdd:COG3206    373 RLEE 376
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
241-880 4.62e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 4.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  241 TLSRTATDLLQAKRQIfTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEMEKDRKienlnakEIQEKQALIDELNTRVVEE 320
Cdd:COG4913    236 DLERAHEALEDAREQI-ELLEPIRELAERYAAARERLAELEYLRAALRLWFAQR-------RLELLEAELEELRAELARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  321 EKKTVELKNKVTTADELLGGLHEQLTQR-NQEIQSLKLELGNSQQNERKCSEEIKELMRTVEELQkrnlkdswLETSAVR 399
Cdd:COG4913    308 EAELERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLEALLAALG--------LPLPASA 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  400 RVEQETQRKLSHLQAELDEMYGKQivqmkQELINQHMSQIEELKSQH---KREMENTLKSDTNaaISKEQVNLMNAAINE 476
Cdd:COG4913    380 EEFAALRAEAAALLEALEEELEAL-----EEALAEAEAALRDLRRELrelEAEIASLERRKSN--IPARLLALRDALAEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  477 LNVRlqethaqKEELK--GELGVVLGEKS--------ALQSQSNDLLEEVRFLREQVQKARQTIAEQENRLSEARKSLST 546
Cdd:COG4913    453 LGLD-------EAELPfvGELIEVRPEEErwrgaierVLGGFALTLLVPPEHYAAALRWVNRLHLRGRLVYERVRTGLPD 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  547 VEDLKAEivAASESRKeLELKhEAEITNYkiklemLEKEKNAVLDRM-AESQEaELERLRTQL----LFSHEEEL-SKLK 620
Cdd:COG4913    526 PERPRLD--PDSLAGK-LDFK-PHPFRAW------LEAELGRRFDYVcVDSPE-ELRRHPRAItragQVKGNGTRhEKDD 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  621 EDLEVEHRI----NIEKLKdnlgiHYKQQIDGLQNEMNrkmesmqcETDNLITQQNQLILENSKLRDLQECLVNSKSEEM 696
Cdd:COG4913    595 RRRIRSRYVlgfdNRAKLA-----ALEAELAELEEELA--------EAEERLEALEAELDALQERREALQRLAEYSWDEI 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  697 NL-----QINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQLkekeDDLQEKCAQLDAENNILKEEKRVLEDKLk 771
Cdd:COG4913    662 DVasaerEIAELEAELERLDASSDDLAALEEQLEELEAELEELEEEL----DELKGEIGRLEKELEQAEEELDELQDRL- 736

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  772 myspseqEERSIAVDPSTSKSADSRWQKevAMLRKETEDLQQQclyLNEEIEKQRNTFAFAEKNFEVNYQELQREYTCLL 851
Cdd:COG4913    737 -------EAAEDLARLELRALLEERFAA--ALGDAVERELREN---LEERIDALRARLNRAEEELERAMRAFNREWPAET 804

                          650       660       670
                   ....*....|....*....|....*....|
gi 1039770159  852 K-IRDDLEATQtkqalEYESKLRALEEELL 880
Cdd:COG4913    805 AdLDADLESLP-----EYLALLDRLEEDGL 829
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
147-554 4.80e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.38  E-value: 4.80e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  147 EKELAEKQHDIEELTQELEEMRASFGT--------EGLKQLQEFEAAIKQRDGIITQLTANLQQARREKD---DTMVEFL 215
Cdd:COG4717     87 EEEYAELQEELEELEEELEELEAELEElreeleklEKLLQLLPLYQELEALEAELAELPERLEELEERLEelrELEEELE 166

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  216 ELTEQSQKLQIQFQHLQANETLQN-STLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEMEKDRK 294
Cdd:COG4717    167 ELEAELAELQEELEELLEQLSLATeEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLK 246

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  295 ienlNAKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEIK 374
Cdd:COG4717    247 ----EARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELE 322

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  375 ELMRTV---EELQKRNLKDSWLETSAVRRV-----EQETQRKLSHLQAELDEMYGKQIVQMKQELINQHMsQIEELKSqh 446
Cdd:COG4717    323 ELLAALglpPDLSPEELLELLDRIEELQELlreaeELEEELQLEELEQEIAALLAEAGVEDEEELRAALE-QAEEYQE-- 399

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  447 KREMENTLKSDTNAAISKEQVNLMNAAINELNVRLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRF--LREQVQ 524
Cdd:COG4717    400 LKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELaeLLQELE 479

                          410       420       430
                   ....*....|....*....|....*....|
gi 1039770159  525 KARQTIAEQENRLSEARKSLSTVEDLKAEI 554
Cdd:COG4717    480 ELKAELRELAEEWAALKLALELLEEAREEY 509
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 553-885 5.30e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.58  E-value: 5.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  553 EIVAASESRKELELKHEAEITNYKIKLEMLEKEKNAVLDRMAESQ----EAELERLRTQLLFSHEEELSKLKEDLEVE-- 626
Cdd:pfam02463  145 EIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIidleELKLQELKLKEQAKKALEYYQLKEKLELEee 224

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  627 ---------HRINIEKLKDNLGIHYKQQIDGLQNEMNRKMESMQcETDNLITQQNQLILENSKLRDLQECLVNSKSEEMN 697
Cdd:pfam02463  225 yllyldylkLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLA-QVLKENKEEEKEKKLQEEELKLLAKEEEELKSELL 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  698 LQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQ------EKCAQLDAENNILKEEKRVLEDKLK 771
Cdd:pfam02463  304 KLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREaeeeeeEELEKLQEKLEQLEEELLAKKKLES 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  772 MYSPSEQEERSIAVDPSTSKSADSRWQKEVAMLRKETEDLQQQCLYLNEEIEKQRNTFAFAEKNFEVNYQELQREyTCLL 851
Cdd:pfam02463  384 ERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQEL-KLLK 462

                          330       340       350
                   ....*....|....*....|....*....|....
gi 1039770159  852 KIRDDLEATQTKQALEYESKLRALEEELLSKRGN 885
Cdd:pfam02463  463 DELELKKSEDLLKETQLVKLQEQLELLLSRQKLE 496
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 598-884 6.88e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 49.28  E-value: 6.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  598 EAELERLRTQLlfSHEEELSKLKEDLEvehriniEKLKDNLGIHYKQQIDGLQ------NEMNRKMESMQCETDNLITQQ 671
Cdd:TIGR02168  199 ERQLKSLERQA--EKAERYKELKAELR-------ELELALLVLRLEELREELEelqeelKEAEEELEELTAELQELEEKL 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  672 NQLILENSKLRDLQEcLVNSKSEEMNLQINELQKEIEILKQE----EKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQE 747
Cdd:TIGR02168  270 EELRLEVSELEEEIE-ELQKELYALANEISRLEQQKQILRERlanlERQLEELEAQLEELESKLDELAEELAELEEKLEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  748 KCAQLDAENNILKEEKRVLEDKLKMYSPSEQEERSIAVDPSTSKSADSRWQKEVAMLRKETEDLQQQCLYLNEEIEKQRN 827
Cdd:TIGR02168  349 LKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK 428

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039770159  828 TFAFAEKN-FEVNYQELQREYTCLLKIRDDLEA---TQTKQALEYESKLRALEEELLSKRG 884
Cdd:TIGR02168  429 KLEEAELKeLQAELEELEEELEELQEELERLEEaleELREELEEAEQALDAAERELAQLQA 489
PTZ00121 PTZ00121
MAEBL; Provisional
 514-1080 7.36e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.98  E-value: 7.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  514 EEVRFLRE--QVQKARQtiAEQENRLSEARKSlstVEDLKAEIVA-ASESRKELELKHEAEITNYKIKLEMLEKEKNAVL 590
Cdd:PTZ00121  1191 EELRKAEDarKAEAARK--AEEERKAEEARKA---EDAKKAEAVKkAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHF 1265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  591 DRMAESQEAELERLRTQLlfSHEEELSKLKEDLEVEHRINIEKLKDNLGIHYK-QQIDGLQNEMNRKMESMQCETDNLIT 669
Cdd:PTZ00121  1266 ARRQAAIKAEEARKADEL--KKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKaDEAKKKAEEAKKKADAAKKKAEEAKK 1343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  670 QQNQLILENSKLRDLQEClVNSKSEEMNLQINELQKEIEILKQ--EEKEKG-TLEQEVQELQLKTEQLEK--QLKEKEDD 744
Cdd:PTZ00121  1344 AAEAAKAEAEAAADEAEA-AEEKAEAAEKKKEEAKKKADAAKKkaEEKKKAdEAKKKAEEDKKKADELKKaaAAKKKADE 1422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  745 LQEKCAQLDAENNILK---------EEKRVLEDKLKMYSPSEQEERSIAVDPSTSKSADSRWQKEvamLRKETEDLQQQC 815
Cdd:PTZ00121  1423 AKKKAEEKKKADEAKKkaeeakkadEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADE---AKKKAEEAKKKA 1499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  816 --LYLNEEIEKQRNTFAFAE---KNFEVNYQELQREYTCLLKIRDDLEATQTKQALEY---------ESKLRALEEELLS 881
Cdd:PTZ00121  1500 deAKKAAEAKKKADEAKKAEeakKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELkkaeekkkaEEAKKAEEDKNMA 1579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  882 KRGNPAAPKGKSSGIFPSETLEIGEVVEKDTTELMEKLEVTKREKLELSEKVSGLSEQLKQTHCTINSLSAEVRalkQEK 961
Cdd:PTZ00121  1580 LRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELK---KAE 1656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  962 EQLLLRCGELELLANPSGTENAAVCPVQMSSYQAGLVMGKVGDSGGSISKISKDLAEE-------SKPMIEDKIPFKESG 1034
Cdd:PTZ00121  1657 EENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEkkkaeelKKAEEENKIKAEEAK 1736

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1039770159 1035 REQlllPTRAQKPSHATVEPCESEKLQQELHALKAEQDDLRLQMEA 1080
Cdd:PTZ00121  1737 KEA---EEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEA 1779
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1978-2210 7.40e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 7.40e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1978 DLQKQVKALE------IDVEEQVSRFIELEqEKNAELTDLRQQSQALEKQLEKMRKFLDEQAIDReherdvFQQEIQKLE 2051
Cdd:COG4913    229 ALVEHFDDLErahealEDAREQIELLEPIR-ELAERYAAARERLAELEYLRAALRLWFAQRRLEL------LEAELEELR 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2052 HQLKAVpriqpvsEHQAREVEQLTNHLKEKTDRCSELLLS-----KEQLQRDIQERNEEIEKLECRVRELEQALLAsaep 2126
Cdd:COG4913    302 AELARL-------EAELERLEARLDALREELDELEAQIRGnggdrLEQLEREIERLERELEERERRRARLEALLAA---- 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2127 fpkvedqkrsgaveadpelsleVQLQVERDAtdrkqKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQE 2206
Cdd:COG4913    371 ----------------------LGLPLPASA-----EEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRE 423


                   ....
gi 1039770159 2207 LQQE 2210
Cdd:COG4913    424 LEAE 427
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1919-2282 7.64e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 48.35  E-value: 7.64e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1919 LQELESDQRRVEEERQLLCRQREAMR----------AEAGPVEQQFLQETEKLMKEKLEVQcqaeKVRGDLQKQVKALEI 1988
Cdd:pfam07888   47 LQAQEAANRQREKEKERYKRDREQWErqrrelesrvAELKEELRQSREKHEELEEKYKELS----ASSEELSEEKDALLA 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1989 DVEEQVSRFIELEQEKNAeltdLRQQSQALEKQLEKMR---KFLDEQAIDREHERDVFQQEIQKLEHQLKAVPR-IQPVS 2064
Cdd:pfam07888  123 QRAAHEARIRELEEDIKT----LTQRVLERETELERMKeraKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKeFQELR 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2065 EHQAR----------EVEQLTNHLKEKTDRCSELLLSKEQLqRDIQERNEEIEKLECRVRElEQALLASAEPFPKVE-DQ 2133
Cdd:pfam07888  199 NSLAQrdtqvlqlqdTITTLTQKLTTAHRKEAENEALLEEL-RSLQERLNASERKVEGLGE-ELSSMAAQRDRTQAElHQ 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2134 KRSGAVEADPELSlEVQLQVeRDATDRKQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENRL 2213
Cdd:pfam07888  277 ARLQAAQLTLQLA-DASLAL-REGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEVELGREKDC 354

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2214 FKV-IEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKLqqEVVSTEQQREGARTLPEDEES 2282
Cdd:pfam07888  355 NRVqLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRL--ETVADAKWSEAALTSTERPDS 422
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 2958-3285 8.02e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.58  E-value: 8.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2958 SMQQKQSLEMQLELSSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELgttlkAQHKRLKELEAFRSEVKEKTDEIHFL 3037
Cdd:pfam17380  264 TMTENEFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREV-----ERRRKLEEAEKARQAEMDRQAAIYAE 338

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3038 SDTLAREQKNSLElqwALEKEKARSGHHEGREKE---------ELEDLKFSLEDQKRRNTQLNLLLEQQKQLLNESQQKI 3108
Cdd:pfam17380  339 QERMAMERERELE---RIRQEERKRELERIRQEEiameisrmrELERLQMERQQKNERVRQELEAARKVKILEEERQRKI 415

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3109 ESQKM-LHDAQLSEEQGRNLGLQaLLESEQVRiqEMKSTLDKERELYAQLQS-REDGGQPPPALPSEDLLKELQKQLEEK 3186
Cdd:pfam17380  416 QQQKVeMEQIRAEQEEARQREVR-RLEEERAR--EMERVRLEEQERQQQVERlRQQEEERKRKKLELEKEKRDRKRAEEQ 492

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3187 HSRIVEL-LSETEKYKLDSLQTRQQMEKDRQVHQKTLQTEQ-----EANTQGQKKMQElQSKVEELQRQLQEKRQQVYKL 3260
Cdd:pfam17380  493 RRKILEKeLEERKQAMIEEERKRKLLEKEMEERQKAIYEEErrreaEEERRKQQEMEE-RRRIQEQMRKATEERSRLEAM 571

                          330       340
                   ....*....|....*....|....*.
gi 1039770159 3261 DLEGKRLQGLMQ-EFQKQELEPEEKP 3285
Cdd:pfam17380  572 EREREMMRQIVEsEKARAEYEATTPI 597
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 294-885 8.03e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 48.89  E-value: 8.03e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  294 KIENLNAKEIQEkqalideLNTRVVEEEKKTVELKNKVTTADELLG---GLHEQLTQRNQEIQSLKLELGNSQQNERKCS 370
Cdd:TIGR01612 1059 EIEKEIGKNIEL-------LNKEILEEAEINITNFNEIKEKLKHYNfddFGKEENIKYADEINKIKDDIKNLDQKIDHHI 1131

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  371 EEIKELMRTVE------ELQKRNLKDSwLETSAVRRVEQETQRKLSHLQAELDEMygKQIVQMKQELINQhMSQIEELKS 444
Cdd:TIGR01612 1132 KALEEIKKKSEnyideiKAQINDLEDV-ADKAISNDDPEEIEKKIENIVTKIDKK--KNIYDEIKKLLNE-IAEIEKDKT 1207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  445 QHKR---------EMENTL---KSDTNAAISKEQVNLMNAAINELNvrlqETHAQKEELKGELGVVLGEKSALQ--SQSN 510
Cdd:TIGR01612 1208 SLEEvkginlsygKNLGKLfleKIDEEKKKSEHMIKAMEAYIEDLD----EIKEKSPEIENEMGIEMDIKAEMEtfNISH 1283

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  511 DLLEEVRFLREQVQKARQTIAEQENRLSEARKSLSTVEDLKAEI-VAASESRkelelKHEAEITNYKIKLE------MLE 583
Cdd:TIGR01612 1284 DDDKDHHIISKKHDENISDIREKSLKIIEDFSEESDINDIKKELqKNLLDAQ-----KHNSDINLYLNEIAniynilKLN 1358

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  584 KEKNaVLDRMAESQEaELERLRTQL---LFSHEEELSKLKEDLEVEH-RINIEKLKDNLGIH--------YKQQIDGLQN 651
Cdd:TIGR01612 1359 KIKK-IIDEVKEYTK-EIEENNKNIkdeLDKSEKLIKKIKDDINLEEcKSKIESTLDDKDIDecikkikeLKNHILSEES 1436

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  652 EMNRKMESMQCETDNLITQQNQLILENSKLRDLQECLVNSKSEEMNLQINELQKEI---------------------EIL 710
Cdd:TIGR01612 1437 NIDTYFKNADENNENVLLLFKNIEMADNKSQHILKIKKDNATNDHDFNINELKEHIdkskgckdeadknakaieknkELF 1516

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  711 KQEEKEKGTLEQEVQELQLK---------TEQLEKQLKEKEDDLQEKCAQLDAENNILKEEKRVLEDKLKMYSPSEQEer 781
Cdd:TIGR01612 1517 EQYKKDVTELLNKYSALAIKnkfaktkkdSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKA-- 1594

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  782 siAVDPSTSKSADSRWQKEVAMLRKETEDlqqqCLYLNEEIEKQRNTFAFAEKNFEV-----NYQELQREYTCLLKIRDD 856
Cdd:TIGR01612 1595 --AIDIQLSLENFENKFLKISDIKKKIND----CLKETESIEKKISSFSIDSQDTELkengdNLNSLQEFLESLKDQKKN 1668

                          650       660
                   ....*....|....*....|....*....
gi 1039770159  857 LEaTQTKQALEYESKLRALEEELLSKRGN 885
Cdd:TIGR01612 1669 IE-DKKKELDELDSEIEKIEIDVDQHKKN 1696
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
2047-2231 8.58e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 48.70  E-value: 8.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2047 IQKLEHQLKAV--PRIQPVSEHQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQallasa 2124
Cdd:COG2433    382 LEELIEKELPEeePEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARS------ 455

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2125 epfpkvedqkrsgaveadpelslevqlqvERDATDRKQKEITNLEEQLEQFREELENKNDEVQELlmQLEIQRKESTTRL 2204
Cdd:COG2433    456 -----------------------------EERREIRKDREISRLDREIERLERELEEERERIEEL--KRKLERLKELWKL 504

                          170       180
                   ....*....|....*....|....*...
gi 1039770159 2205 qELQQENRLFKVIEE-QKEQIQDLETQI 2231
Cdd:COG2433    505 -EHSGELVPVKVVEKfTKEAIRRLEEEY 531
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1539-2304 8.62e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.91  E-value: 8.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1539 SRQLILNEQLEDMRQELVRQyEEHQQATEMLRQAHMQQMERQREDQEQLQEEIKRL--NEQLAQKSSIdtehvvsererv 1616
Cdd:TIGR02169  230 KEKEALERQKEAIERQLASL-EEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeEEQLRVKEKI------------ 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1617 llEELEAlkQLPLAGRKELCCELRHSSTQTQDGHDDQEVEEQTLKDKTLERSPEDALLDRNLSNERYALKKANNRLLKIL 1696
Cdd:TIGR02169  297 --GELEA--EIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAE 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1697 LEVVKTTSAAeetigrhvlgildrsskgqtassllWRSEADASATtcAPEDCARAMDESIPSYpgtaiathdsiwSKVTE 1776
Cdd:TIGR02169  373 LEEVDKEFAE-------------------------TRDELKDYRE--KLEKLKREINELKREL------------DRLQE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1777 EGAELSQRLVRSGFAGPVIDPENEElmlnissrLQAAVEKLLEAISETNTQLEhakvtQTELMRESFRQKQEATESlhcl 1856
Cdd:TIGR02169  414 ELQRLSEELADLNAAIAGIEAKINE--------LEEEKEDKALEIKKQEWKLE-----QLAADLSKYEQELYDLKE---- 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1857 eELRERLQEESRAREQLAE---ELNKAESVIDGYSDEKTLFERQIQ----EKTDIIEHLEQEVLCMN----NRLQELESD 1925
Cdd:TIGR02169  477 -EYDRVEKELSKLQRELAEaeaQARASEERVRGGRAVEEVLKASIQgvhgTVAQLGSVGERYATAIEvaagNRLNNVVVE 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1926 QRRVEEERQLLCRQREAMRA-------------------EAGPV---------EQQFLQETEKLMKEKLEVQCQAEKVRG 1977
Cdd:TIGR02169  556 DDAVAKEAIELLKRRKAGRAtflplnkmrderrdlsilsEDGVIgfavdlvefDPKYEPAFKYVFGDTLVVEDIEAARRL 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1978 DLQKQVKALEIDVEEQ----------VSRFIELEQEKNAELTDLRQQSQALEKQLEKMRKFLDEQaidrEHERDVFQQEI 2047
Cdd:TIGR02169  636 MGKYRMVTLEGELFEKsgamtggsraPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRI----ENRLDELSQEL 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2048 QKLEHQLKAVP-RIQPVSEHQAREVEQLTNhLKEKTDRCSELLLSKEQ----LQRDIQERNEEIEKLECRVRELEQALla 2122
Cdd:TIGR02169  712 SDASRKIGEIEkEIEQLEQEEEKLKERLEE-LEEDLSSLEQEIENVKSelkeLEARIEELEEDLHKLEEALNDLEARL-- 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2123 SAEPFPKVEDQKRsgaveadpELSLEVQLQVER-DATDRKQKEITNLEEQLEQFREELENKNDEvqellmqLEIQRKEST 2201
Cdd:TIGR02169  789 SHSRIPEIQAELS--------KLEEEVSRIEARlREIEQKLNRLTLEKEYLEKEIQELQEQRID-------LKEQIKSIE 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2202 TRLQELQQEnrlfkvIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQREGARTLPEDEE 2281
Cdd:TIGR02169  854 KEIENLNGK------KEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE 927

                          810       820
                   ....*....|....*....|...
gi 1039770159 2282 SFKHQLDKVTAEKLVLEQQVETT 2304
Cdd:TIGR02169  928 ALEEELSEIEDPKGEDEEIPEEE 950
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 343-563 9.27e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 9.27e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  343 EQLTQRNQEIQSLKLELGNSQQNERKCSEEIKELMRTVEELQKRnLKDSWLETSAVRRVEQETQRKLSHLQAELDE---M 419
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARR-IRALEQELAALEAELAELEKEIAELRAELEAqkeE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  420 YGKQIVQMkqelinQHMSQIEELK----SQHKREMENTLK--SDTNAAIsKEQVNLMNAAINELNVRLQETHAQKEELKG 493
Cdd:COG4942    106 LAELLRAL------YRLGRQPPLAlllsPEDFLDAVRRLQylKYLAPAR-REQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  494 ELgvvlgekSALQSQSNDLLEEVRFLREQVQKARQTIAEQENRLSEARKSLSTVEDLKAEIVAASESRKE 563
Cdd:COG4942    179 LL-------AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 3016-3284 9.38e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.53  E-value: 9.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3016 RLKELEAFRSEVKEKTDEIHFLSDTLAREQKNSLELQWALEKEKARSGHHEGREKEELEDLKFSLEdqkrrntqlnllle 3095
Cdd:TIGR02169  682 RLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS-------------- 747

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3096 qqkqllnESQQKIESQKmlhdaqlseeqgrnlglqALLESEQVRIQEMKSTLDKERELYAQLQSREDGGQPPpalpseDL 3175
Cdd:TIGR02169  748 -------SLEQEIENVK------------------SELKELEARIEELEEDLHKLEEALNDLEARLSHSRIP------EI 796

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3176 LKELQKqLEEKHSRIVELLSETEKYKLDSLQTRQQMEKDRQVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQ 3255
Cdd:TIGR02169  797 QAELSK-LEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEA 875

                          250       260
                   ....*....|....*....|....*....
gi 1039770159 3256 QVYKLDLEGKRLQGLMQEFQKQELEPEEK 3284
Cdd:TIGR02169  876 ALRDLESRLGDLKKERDELEAQLRELERK 904
PRK12704 PRK12704
phosphodiesterase; Provisional
 670-781 1.16e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 47.85  E-value: 1.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  670 QQNQLILENSKLRdlqeclVNSKSEEMNLQINElqkEIEILKQE-EKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEK 748
Cdd:PRK12704    38 EEAKRILEEAKKE------AEAIKKEALLEAKE---EIHKLRNEfEKELRERRNELQKLEKRLLQKEENLDRKLELLEKR 108

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1039770159  749 CAQLDAENNILKEEKRVLEDKLKMYSPSEQEER 781
Cdd:PRK12704   109 EEELEKKEKELEQKQQELEKKEEELEELIEEQL 141
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 2150-2262 1.20e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 48.15  E-value: 1.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2150 QLQVERDATDRKQKEITnlEEQLEQFREELENKNDEVQELLMQLEiQRKESTTRLQELQQEnrlfkvIEEQKEQIQDLET 2229
Cdd:COG0542    422 QLEIEKEALKKEQDEAS--FERLAELRDELAELEEELEALKARWE-AEKELIEEIQELKEE------LEQRYGKIPELEK 492

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1039770159 2230 QIERLMSEREHEKKQREEEVE---------QLTGV-VEKLQQE 2262
Cdd:COG0542    493 ELAELEEELAELAPLLREEVTeediaevvsRWTGIpVGKLLEG 535
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1915-2461 1.27e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.04  E-value: 1.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1915 MNNRLQELESDQRRVEEERQLLCRQR-EAMRAEAGPVEQQFLQETEKLMKEKLEVQCQAEKVRGDLQKQVKALEIDVEEQ 1993
Cdd:pfam02463  181 ETENLAELIIDLEELKLQELKLKEQAkKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEI 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1994 VSRFIELEQEKNAELTDLRQQSQALEKQLEKMrKFLDEQAIDREHERDVFQQEIQKLEHQLKAVPRIQPVSEHQAREVEQ 2073
Cdd:pfam02463  261 EKEEEKLAQVLKENKEEEKEKKLQEEELKLLA-KEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2074 LTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQALLASAEPFPKVEDQKRSGAVEADPELSLEvqlQV 2153
Cdd:pfam02463  340 LEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELA---RQ 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2154 ERDATDRKQKEITNLEEQLEQFREELENKNDEVQEllmQLEIQRKESTTRLQELQQENRLFKVIEEQKEQIQdLETQIER 2233
Cdd:pfam02463  417 LEDLLKEEKKEELEILEEEEESIELKQGKLTEEKE---ELEKQELKLLKDELELKKSEDLLKETQLVKLQEQ-LELLLSR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2234 LMSEREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQREGARTLPEDEESFKHQLDKVTAEKLVLEQQVETTNQVMTHMNN 2313
Cdd:pfam02463  493 QKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTE 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2314 VLKEINFKMDQITQSLCNLNK-ECASNEELPSLPKESVHMTVHELGSDNLQPEDAPAQDVTKPLEKQTSLTRLQKSPEAS 2392
Cdd:pfam02463  573 LPLGARKLRLLIPKLKLPLKSiAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGV 652

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039770159 2393 RTQEIESLASSVGAKDVELTQCREQTETIQEQAQSETDRLQKKLTDLQRSLEKFAAALVSQVQMEAAQE 2461
Cdd:pfam02463  653 SLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEE 721
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2006-2234 1.31e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.99  E-value: 1.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2006 AELTDLRQQSQALEKQLEKMRKFLDEQAIDREHERDvfQQEIQKLEHQLKAVPriqpvSEHQAREVEQLTNhlkektdRC 2085
Cdd:COG4913    232 EHFDDLERAHEALEDAREQIELLEPIRELAERYAAA--RERLAELEYLRAALR-----LWFAQRRLELLEA-------EL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2086 SELLLSKEQLQRDIQERNEEIEKLECRVRELEQALLASaepfpkvedqkrSGAVEADpelsLEVQLQVERDATDRKQKEI 2165
Cdd:COG4913    298 EELRAELARLEAELERLEARLDALREELDELEAQIRGN------------GGDRLEQ----LEREIERLERELEERERRR 361

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2166 TNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQE-NRLFKVIEEQKEQIQDLETQIERL 2234
Cdd:COG4913    362 ARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEAlAEAEAALRDLRRELRELEAEIASL 431
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1868-2316 1.33e-04

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 47.81  E-value: 1.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1868 RAREQLAEELNKAESVIDG-YSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQEL-------ESDQRRVEEERQLLCRQ 1939
Cdd:pfam05557   61 EKREAEAEEALREQAELNRlKKKYLEALNKKLNEKESQLADAREVISCLKNELSELrrqiqraELELQSTNSELEELQER 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1940 REAMRAEAGPVEQQF--LQETEKLMKEKlEVQCQAEKVRGDLQKQVKALEIDVEEQVSRFIELEQEK------NAELTDL 2011
Cdd:pfam05557  141 LDLLKAKASEAEQLRqnLEKQQSSLAEA-EQRIKELEFEIQSQEQDSEIVKNSKSELARIPELEKELerlrehNKHLNEN 219

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2012 RQQSQALEKQLEKMRKFLD------EQAIDREHERDVFQQEIQKLEHQLKAVPRIQPVSEHQAREVEQL----------- 2074
Cdd:pfam05557  220 IENKLLLKEEVEDLKRKLEreekyrEEAATLELEKEKLEQELQSWVKLAQDTGLNLRSPEDLSRRIEQLqqreivlkeen 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2075 ---TNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELE-QALLASAEpfpkvEDQKRSGAVEADPELSLE-- 2148
Cdd:pfam05557  300 sslTSSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQrRVLLLTKE-----RDGYRAILESYDKELTMSny 374

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2149 -----VQLQVERDATDRKQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQE--NRLFKVIEEQK 2221
Cdd:pfam05557  375 spqllERIEEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLADPSYSKEevDSLRRKLETLE 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2222 EQIQDLETQIERLMSEREHE------------------------KKQREEEVEQLTGVVEKLQQEVVSTEQQREGARTLP 2277
Cdd:pfam05557  455 LERQRLREQKNELEMELERRclqgdydpkktkvlhlsmnpaaeaYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLP 534

                          490       500       510
                   ....*....|....*....|....*....|....*....
gi 1039770159 2278 EDEESFKHQldkvtaEKLVLEQQVETTNQVMTHMNNVLK 2316
Cdd:pfam05557  535 ETTSTMNFK------EVLDLRKELESAELKNQRLKEVFQ 567
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1895-2461 1.56e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.86  E-value: 1.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1895 ERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQL---LCRQREAMRAEAGPVEQQF---LQETEKLMKEKLEV 1968
Cdd:pfam01576   11 EEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAeteLCAEAEEMRARLAARKQELeeiLHELESRLEEEEER 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1969 QCQAEKVRGDLQKQVKALEIDVEEQVSRFIELEQEKNAeltdlrqqSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQ 2048
Cdd:pfam01576   91 SQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVT--------TEAKIKKLEEDILLLEDQNSKLSKERKLLEERIS 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2049 KLEHQL----KAVPRIQPVSEHQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQAL---- 2120
Cdd:pfam01576  163 EFTSNLaeeeEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLakke 242

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2121 --LASAEPFPKVEDQKRSGAVEADPEL-----SLEVQLQVERDATDRKQKEITNLEEQLEQFREELENKND--------- 2184
Cdd:pfam01576  243 eeLQAALARLEEETAQKNNALKKIRELeaqisELQEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDttaaqqelr 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2185 -----EVQELLMQLEIQRKESTTRLQELQQenRLFKVIEEQKEQIQdletQIERLMSEREHEKKQREEEVEQLTGVVEKL 2259
Cdd:pfam01576  323 skreqEVTELKKALEEETRSHEAQLQEMRQ--KHTQALEELTEQLE----QAKRNKANLEKAKQALESENAELQAELRTL 396

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2260 QQEVVSTEQQREGARTLPEDEESFKHQLDKVTAEklvLEQQVETTNQVMTHMNNVLKEINFKMDQITQSLCNLNKECASN 2339
Cdd:pfam01576  397 QQAKQDSEHKRKKLEGQLQELQARLSESERQRAE---LAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDT 473

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2340 EEL---PSLPKESVHMTVHELGSD--NLQPEDAPAQDVTKPLEKQTSLTRLQKSPEASRTQEIESLASSVGAKDVELTQC 2414
Cdd:pfam01576  474 QELlqeETRQKLNLSTRLRQLEDErnSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRE 553

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1039770159 2415 REQTETIQEQAQSETDRLQKKLTDLQRSLEKFAAALVSQVQMEAAQE 2461
Cdd:pfam01576  554 LEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLE 600
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 268-955 1.68e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 47.73  E-value: 1.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  268 KKEEDLQAQISFLQEKLRAFEMEKDRKIENLNAKEIQEK-------QALIDELNTRVVEEEKKTVELKNKVTTADELLGG 340
Cdd:TIGR00606  279 KQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKerelvdcQRELEKLNKERRLLNQEKTELLVEQGRLQLQADR 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  341 LHEQLTQRNQEIQSLKLELGNSQQNERKCSE-EIKELMRTVEELQKRNLKDSWLETSAVRRVEQETQRKLSHLQAELDEM 419
Cdd:TIGR00606  359 HQEHIRARDSLIQSLATRLELDGFERGPFSErQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGL 438

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  420 ygKQIVQMKQELINQHMSQIeelksQHKREMENTLKSDTNAAISKEQvnlmnaainelNVRLQETHAQKEELKGELGVVL 499
Cdd:TIGR00606  439 --GRTIELKKEILEKKQEEL-----KFVIKELQQLEGSSDRILELDQ-----------ELRKAERELSKAEKNSLTETLK 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  500 GEKSALQSQSNDLLEEVRFLREQVqkarqtiaEQENRLSEARKSLSTVEDLKA---EIVAASESRKELELKHEAEITNYK 576
Cdd:TIGR00606  501 KEVKSLQNEKADLDRKLRKLDQEM--------EQLNHHTTTRTQMEMLTKDKMdkdEQIRKIKSRHSDELTSLLGYFPNK 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  577 IKLE----MLEKEKNAVLDRMAESQE--AELERLRTQL---LFSHEEELSKLKEDL-----EVEHRINIEKLKDNLGIHY 642
Cdd:TIGR00606  573 KQLEdwlhSKSKEINQTRDRLAKLNKelASLEQNKNHInneLESKEEQLSSYEDKLfdvcgSQDEESDLERLKEEIEKSS 652

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  643 KQQ--IDGLQNEMNRKMESMQ------CETDNLITQQNQLILENSKLRDLQECLVNSKSEEMNLQINELQKEIEIL---- 710
Cdd:TIGR00606  653 KQRamLAGATAVYSQFITQLTdenqscCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMlgla 732

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  711 KQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAENNILKEEKRVLEDKLKM---YSPSEQEERSIAVDP 787
Cdd:TIGR00606  733 PGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMerfQMELKDVERKIAQQA 812

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  788 STSKSADSrwQKEVAMLRKETEDLQQQCLYLNEEIEKQRNTFAFAEKNFEVNYQELQREYTCLLKIRddlEATQTKQALE 867
Cdd:TIGR00606  813 AKLQGSDL--DRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIG---TNLQRRQQFE 887

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  868 YESKLRALEEELLSKrgnpaAPKGKSSGIFPSETLeigevVEKDTTELMEKLEVTKREKLELSEKVSGLSEQLKQTHCTI 947
Cdd:TIGR00606  888 EQLVELSTEVQSLIR-----EIKDAKEQDSPLETF-----LEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYM 957


                   ....*...
gi 1039770159  948 NSLSAEVR 955
Cdd:TIGR00606  958 KDIENKIQ 965
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
397-974 1.69e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.73  E-value: 1.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  397 AVRRVEQETQRKLSHLQAELDEMYGKQIVqmkqELINQHMSQIEELKSQHKREMENTLKS----DTNAAI------SKEQ 466
Cdd:PRK02224   177 GVERVLSDQRGSLDQLKAQIEEKEEKDLH----ERLNGLESELAELDEEIERYEEQREQAretrDEADEVleeheeRREE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  467 VNLMNAAINELNVRLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKARQTIAEQENRLSEARKSLST 546
Cdd:PRK02224   253 LETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEE 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  547 VEdlkaeiVAASEsrkelelkHEAEITNYKIKLEMLE------KEKNAVLDRMAESQEAELERLRTQL--LFSHEEELSK 618
Cdd:PRK02224   333 CR------VAAQA--------HNEEAESLREDADDLEeraeelREEAAELESELEEAREAVEDRREEIeeLEEEIEELRE 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  619 LKEDLEVEhrinIEKLKDNLgihykqqiDGLQNEMNRKMESMQCETDNLITQQNQlILENSKLRDLQECLVNSkseemnl 698
Cdd:PRK02224   399 RFGDAPVD----LGNAEDFL--------EELREERDELREREAELEATLRTARER-VEEAEALLEAGKCPECG------- 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  699 QINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEdDLQEKCAQLDAenniLKEEKRVLEDKLkmyspSEQ 778
Cdd:PRK02224   459 QPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAE-DLVEAEDRIER----LEERREDLEELI-----AER 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  779 EERsiaVDPSTSKSADSRwqKEVAMLRKETEDLQQQCLYLNEEIEKQRNTFAFAEKNFEVNYQELQReytcLLKIRDDL- 857
Cdd:PRK02224   529 RET---IEEKRERAEELR--ERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIES----LERIRTLLa 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  858 ---EATQTKQAL-EYESKLRALEEE----LLSKRGNPAAPKGKSSGIFPSETLEIGEVVEKDTTELMEKLEVTKREKLEL 929
Cdd:PRK02224   600 aiaDAEDEIERLrEKREALAELNDErrerLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDL 679

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1039770159  930 SEKVSGLSEQLKqthctinslsaEVRALKQEKEQLLLRCGELELL 974
Cdd:PRK02224   680 QAEIGAVENELE-----------ELEELRERREALENRVEALEAL 713
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 2132-2262 1.75e-04

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 46.93  E-value: 1.75e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  2132 DQKRSGAVEADPELSLEVQLQVE-----RDATDRKQKEITNLEEQLEQFRE----ELENKNDEVQELLMQLEIQRKESTT 2202
Cdd:smart00787  150 DENLEGLKEDYKLLMKELELLNSikpklRDRKDALEEELRQLKQLEDELEDcdptELDRAKEKLKKLLQEIMIKVKKLEE 229

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  2203 RLQELQQenrLFKVIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQE 2262
Cdd:smart00787  230 LEEELQE---LESKIEDLTNKKSELNTEIAEAEKKLEQCRGFTFKEIEKLKEQLKLLQSL 286
PRK01156 PRK01156
chromosome segregation protein; Provisional
 271-770 1.85e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 47.59  E-value: 1.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  271 EDLQAQISFLQEKLRAFEMEKDRKIENLNAKEiQEKQALIDELNTRVVEEEKKTvELKNKVTTADELLGGLHEQltqrNQ 350
Cdd:PRK01156   200 ENIKKQIADDEKSHSITLKEIERLSIEYNNAM-DDYNNLKSALNELSSLEDMKN-RYESEIKTAESDLSMELEK----NN 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  351 EIQSLKLELGNSQQNE-RKCSEEIKELMRTVEELQkrNLKDSWLETSAVRRVEQETQRKLSHLQAELDEMYGKQ-----I 424
Cdd:PRK01156   274 YYKELEERHMKIINDPvYKNRNYINDYFKYKNDIE--NKKQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKsryddL 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  425 VQMKQELINQHM---SQIEELKSQHKREMENTLKSDTNAAISKEQVNLMNAAINELNVRLQETHAQKEELKGELGVVLGE 501
Cdd:PRK01156   352 NNQILELEGYEMdynSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQR 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  502 KSALQSQSNDLLEEVRFLR--------------EQVQKARQTIAEQENRL-SEARKSLSTVEDLKAEIVAASESRKELEL 566
Cdd:PRK01156   432 IRALRENLDELSRNMEMLNgqsvcpvcgttlgeEKSNHIINHYNEKKSRLeEKIREIEIEVKDIDEKIVDLKKRKEYLES 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  567 KHEAEITNYKIKLEMLEKEKNAVLDRMAESQEAEL--ERLRTQLLFSHEEELSKLKED----LEVEHRINIEKL---KDN 637
Cdd:PRK01156   512 EEINKSINEYNKIESARADLEDIKIKINELKDKHDkyEEIKNRYKSLKLEDLDSKRTSwlnaLAVISLIDIETNrsrSNE 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  638 LGIHYKQQIDGLqNEMNRKMESMQCETDNLITQ-QNQLILENSKLRDLQeclvnskseEMNLQINELQKEIEILKQEEKE 716
Cdd:PRK01156   592 IKKQLNDLESRL-QEIEIGFPDDKSYIDKSIREiENEANNLNNKYNEIQ---------ENKILIEKLRGKIDNYKKQIAE 661

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1039770159  717 KGTLEQEVQELQLKTEQLEKQLKEKE---DDLQEKCAQLDAENNILKEEKRVLEDKL 770
Cdd:PRK01156   662 IDSIIPDLKEITSRINDIEDNLKKSRkalDDAKANRARLESTIEILRTRINELSDRI 718
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1894-2457 1.88e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 47.41  E-value: 1.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1894 FERQIQEKTDIIEHleqevlcmNNRLQELESDQRRVEEERQLLCRQREAMRAEAGPVEQQFLQETEKLMKEKLEVQCQAE 1973
Cdd:pfam05483  136 LEEEIQENKDLIKE--------NNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQAE 207

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1974 KVRGDLQKQVKaleidveEQVSRFIELEQEKNAELTDLRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEHQ 2053
Cdd:pfam05483  208 NARLEMHFKLK-------EDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQ 280

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2054 LKAVPRIQPVSEHQAREVEQLTNHLKEKTDRCSELllsKEQLQRDIQERNEEIEKLECRVRELEQALLASAEPFPKVEDQ 2133
Cdd:pfam05483  281 DENLKELIEKKDHLTKELEDIKMSLQRSMSTQKAL---EEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEAT 357

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2134 KrsgaveadpeLSLEVQLQVERDATDRKQKEITNLEEQLEQFREELE-------NKNDEVQELLM------QLEIQRKES 2200
Cdd:pfam05483  358 T----------CSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEemtkfknNKEVELEELKKilaedeKLLDEKKQF 427

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2201 TTRLQELQ-QENRLFKVIEEQKEQIQDLETQIERLMSEREHEKKQREE-----EVEQLTGVVEKLQQEVVSTEQQREGAR 2274
Cdd:pfam05483  428 EKIAEELKgKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDlktelEKEKLKNIELTAHCDKLLLENKELTQE 507

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2275 TLPEDEESFKHQLDKVTAEKLV--LEQQVETTNQVMTHMNNVLKEINFKMDQITQSL-CNLNK--ECASNEELPSLPKES 2349
Cdd:pfam05483  508 ASDMTLELKKHQEDIINCKKQEerMLKQIENLEEKEMNLRDELESVREEFIQKGDEVkCKLDKseENARSIEYEVLKKEK 587

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2350 vHMTVHELGSDNLQPEdapAQDVTKPLEKQTSLTRLQKSPEASRTQEIESLASSVGAKDVELTQCREQTETIQEQAQSET 2429
Cdd:pfam05483  588 -QMKILENKCNNLKKQ---IENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEI 663

                          570       580
                   ....*....|....*....|....*...
gi 1039770159 2430 DRLQKKLTDLQRSLEKFAAALVSQVQME 2457
Cdd:pfam05483  664 EDKKISEEKLLEEVEKAKAIADEAVKLQ 691
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1868-2064 2.04e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 2.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1868 RAREQLAEELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAE- 1946
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEl 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1947 ------------AGPVE------------------QQFLQETEKLMKEKLEVQCQAEKVRGDLQKQVKALEIDVEEQvsr 1996
Cdd:COG4942    107 aellralyrlgrQPPLAlllspedfldavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAEL--- 183

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039770159 1997 fieleQEKNAELTDLRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEHQLKAVPRIQPVS 2064
Cdd:COG4942    184 -----EEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1952-2219 2.05e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 47.32  E-value: 2.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1952 QQFLQETEKLMKEklevqcQAEKVRGDLQKQVKALEIDVEEQVSRFIELEQEKNaeLTDLRQQSQALEKQLEKmrkfLDE 2031
Cdd:COG3206    159 EAYLEQNLELRRE------EARKALEFLEEQLPELRKELEEAEAALEEFRQKNG--LVDLSEEAKLLLQQLSE----LES 226

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2032 QAIDREHERDVFQQEIQKLEHQLKAVPRIQPvSEHQAREVEQLTNHLkektdrcSELLLSKEQLQRDIQERNEEIEKLEC 2111
Cdd:COG3206    227 QLAEARAELAEAEARLAALRAQLGSGPDALP-ELLQSPVIQQLRAQL-------AELEAELAELSARYTPNHPDVIALRA 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2112 RVRELEQALLASAEpfpkvedqkrsgaveadpelSLEVQLQVERDATDRKQKEITNLEEQLEQFREELENKNDEVQELLM 2191
Cdd:COG3206    299 QIAALRAQLQQEAQ--------------------RILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLER 358

                          250       260       270
                   ....*....|....*....|....*....|....*
gi 1039770159 2192 QLEIQRKESTT---RLQELQQENRL----FKVIEE 2219
Cdd:COG3206    359 EVEVARELYESllqRLEEARLAEALtvgnVRVIDP 393
Seryl_tRNA_N pfam02403
Seryl-tRNA synthetase N-terminal domain; This domain is found associated with the Pfam tRNA ...
 692-752 2.18e-04

Seryl-tRNA synthetase N-terminal domain; This domain is found associated with the Pfam tRNA synthetase class II domain (pfam00587) and represents the N-terminal domain of seryl-tRNA synthetase.


Pssm-ID: 426757 [Multi-domain]  Cd Length: 108  Bit Score: 43.35  E-value: 2.18e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039770159  692 KSEEMNLQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQL 752
Cdd:pfam02403   44 ELEELQAERNELSKEIGQAKKKKEDADALIAEVKELKDELKALEAELKELEAELDKLLLTI 104
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 2957-3277 2.23e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 47.41  E-value: 2.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2957 CSMQQKQSLEMQLELSSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELGTTLKAQHKRLKELEA-FRSEVKEKTDEIH 3035
Cdd:pfam05483  164 CARSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEeYKKEINDKEKQVS 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3036 FLSDTLAREQKNSLELQWALEKEKARSGHHEGREKEELEDLKFSLEDQKRRNTQLNLLLEQQkqllnesQQKIESQKMLH 3115
Cdd:pfam05483  244 LLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSL-------QRSMSTQKALE 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3116 D---------AQLSEEQGRNLG-LQALLESEQVRIQEMKSTLDKERELYAQLQSREDGgqpppalpSEDLLKELQKQLEE 3185
Cdd:pfam05483  317 EdlqiatktiCQLTEEKEAQMEeLNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEK--------NEDQLKIITMELQK 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3186 KHSRIVELLSETEKYKLDSLQTRQQMEKDrqvhqktlQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQQVYKLDLEGK 3265
Cdd:pfam05483  389 KSSELEEMTKFKNNKEVELEELKKILAED--------EKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLT 460

                          330
                   ....*....|..
gi 1039770159 3266 RLQGLMQEFQKQ 3277
Cdd:pfam05483  461 AIKTSEEHYLKE 472
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2176-2461 2.28e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.36  E-value: 2.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2176 REELENKNDEVQELLMQLEIQRKESTTRLQELQQENRLFKVIEEQKEQIQDLETQIERLMSEREHEKKQR-EEEVEQLTG 2254
Cdd:TIGR02168  174 RKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEElQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2255 VVEKLQQEVVSTEQQREGART-LPEDEESFKHQ---LDKVTAEKLVLEQQVETTNQVMTHMNNVLKEINFKMDQITQSLC 2330
Cdd:TIGR02168  254 ELEELTAELQELEEKLEELRLeVSELEEEIEELqkeLYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLD 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2331 NLNKECASNEElpslpKESVHMTVHELGSDNLQPEDAPAQDVTKPLEKQTSLTRLQKSPEASRTQEIESLASSVGAKDVE 2410
Cdd:TIGR02168  334 ELAEELAELEE-----KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEAR 408

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1039770159 2411 LTQC-REQTETIQEQAQSETDRLQKKLTDLQRSLEKFAAALVSQVQMEAAQE 2461
Cdd:TIGR02168  409 LERLeDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLE 460
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1868-2036 2.34e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.69  E-value: 2.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1868 RAREQLAEELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEA 1947
Cdd:COG1579     24 HRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEALQKEIESLKR 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1948 gpvEQQFLQETEKLMKEKLEvqcqaekvrgDLQKQVKALEIDVEEQVSRFIELEQEKNAELTDLRQQSQALEKQLEKMRK 2027
Cdd:COG1579    104 ---RISDLEDEILELMERIE----------ELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAA 170


                   ....*....
gi 1039770159 2028 FLDEQAIDR 2036
Cdd:COG1579    171 KIPPELLAL 179
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2087-2279 2.52e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.69  E-value: 2.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2087 ELLLSKEQLQRDIQERNEEIEKLECRVRELEQALLAsaepfpkvedqkrsgaveadpelsLEVQLQVERDATDRKQKEIT 2166
Cdd:COG1579     14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEA------------------------AKTELEDLEKEIKRLELEIE 69

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2167 NLEEQLEQFREELEN--KNDEVQELLMQLEIQRKesttRLQELQQEnrlfkvIEEQKEQIQDLETQIERLMSEREHEKKQ 2244
Cdd:COG1579     70 EVEARIKKYEEQLGNvrNNKEYEALQKEIESLKR----RISDLEDE------ILELMERIEELEEELAELEAELAELEAE 139

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1039770159 2245 REEEVEQLTGVVEKLQQEVVSTEQQREGAR-TLPED 2279
Cdd:COG1579    140 LEEKKAELDEELAELEAELEELEAEREELAaKIPPE 175
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2916-3201 2.85e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.98  E-value: 2.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2916 QKADRRSLLAEIEDLRAQINGGKMTLER-EQGTEKSSQELLDCSMQ----QKQSLEMQLELSSLRDRAAELQEQLSSEKM 2990
Cdd:TIGR02169  672 EPAELQRLRERLEGLKRELSSLQSELRRiENRLDELSQELSDASRKigeiEKEIEQLEQEEEKLKERLEELEEDLSSLEQ 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2991 VVAELKSELAQAKLELGTTLKAQHKRLKELEAF-----RSEVKEKTDEIHFLSDTLAREQKNSLELQWALEKEKARSGHH 3065
Cdd:TIGR02169  752 EIENVKSELKELEARIEELEEDLHKLEEALNDLearlsHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL 831

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3066 EgREKEELEDLKFSLEDQKRRNTQLNLLLEQQKQLLNESQQKIESQKMLHDAQLSEEQGRNLGLQALLESEQVRIQEMKS 3145
Cdd:TIGR02169  832 E-KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEA 910

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3146 TLDKERELYAQLQSR----------------EDGGQPPPALPSEDLLKELQK---------------------------- 3181
Cdd:TIGR02169  911 QIEKKRKRLSELKAKlealeeelseiedpkgEDEEIPEEELSLEDVQAELQRveeeiralepvnmlaiqeyeevlkrlde 990

                          330       340
                   ....*....|....*....|....*.
gi 1039770159 3182 ------QLEEKHSRIVELLSETEKYK 3201
Cdd:TIGR02169  991 lkekraKLEEERKAILERIEEYEKKK 1016
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 302-560 3.24e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 46.36  E-value: 3.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  302 EIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEIKELMRtve 381
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERAR--- 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  382 ELQKRNLKDSWLE--------TSAVRRVEqetqrklshlqaeldemYGKQIVQMKQELINQHMSQIEELKSQHKREMENT 453
Cdd:COG3883     94 ALYRSGGSVSYLDvllgsesfSDFLDRLS-----------------ALSKIADADADLLEELKADKAELEAKKAELEAKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  454 LKSDTNAAISKEQVNLMNAAINELNVRLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKARQTIAEQ 533
Cdd:COG3883    157 AELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236

                          250       260
                   ....*....|....*....|....*..
gi 1039770159  534 ENRLSEARKSLSTVEDLKAEIVAASES 560
Cdd:COG3883    237 AAAAAAAASAAGAGAAGAAGAAAGSAG 263
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2116-2310 3.36e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.68  E-value: 3.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2116 LEQALLASAEPFPKVEDQKRSGAVEADPELSLEVQ-LQVERDATDRKQKEITNLEEQLEQFREELENKNDEVQELLMQLE 2194
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKeAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2195 IQR--KESTTRLQELQQENRLFKVIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEklqQEVVSTEQQREG 2272
Cdd:COG4717    127 LLPlyQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE---EELQDLAEELEE 203

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1039770159 2273 ARtlpEDEESFKHQLDKVTAEKLVLEQQVETTNQVMTH 2310
Cdd:COG4717    204 LQ---QRLAELEEELEEAQEELEELEEELEQLENELEA 238
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
236-746 3.56e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.68  E-value: 3.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  236 TLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKE-EDLQAQISFLQEKLRAFEMEKDRKIENlnAKEIQEKQALIDELN 314
Cdd:COG4717     38 TLLAFIRAMLLERLEKEADELFKPQGRKPELNLKElKELEEELKEAEEKEEEYAELQEELEEL--EEELEELEAELEELR 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  315 TRV--VEEEKKTVELKNKVTTADELLGGLH---EQLTQRNQEIQSLKLELGNSQQNERKCSEEIKELMRTVEELQKRNLK 389
Cdd:COG4717    116 EELekLEKLLQLLPLYQELEALEAELAELPerlEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQ 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  390 DSWLETSAVRRVEQETQRKLSHLQAELDemygkqivqmkqelinQHMSQIEELKSQHKREMENTLKSDTNAAIskeqvnL 469
Cdd:COG4717    196 DLAEELEELQQRLAELEEELEEAQEELE----------------ELEEELEQLENELEAAALEERLKEARLLL------L 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  470 MNAAINELNVRLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKARQTIAEQENRLSEARKSLSTVED 549
Cdd:COG4717    254 IAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPD 333

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  550 LKAEIVAASESRKE--LELKHEAEITNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQL--LFSHEEELSKLKEDLEV 625
Cdd:COG4717    334 LSPEELLELLDRIEelQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAeeYQELKEELEELEEQLEE 413

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  626 EHRINIEKLKDNLGIHYKQQIDGLQNEMNRKMEsmqcETDNLITQQNQLILENSKLRDLQEclvnskseemnlqINELQK 705
Cdd:COG4717    414 LLGELEELLEALDEEELEEELEELEEELEELEE----ELEELREELAELEAELEQLEEDGE-------------LAELLQ 476

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|.
gi 1039770159  706 EIEILKQEEKEkgtLEQEVQELQLKTEQLEKQLKEKEDDLQ 746
Cdd:COG4717    477 ELEELKAELRE---LAEEWAALKLALELLEEAREEYREERL 514
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 1810-2245 3.64e-04

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 46.21  E-value: 3.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1810 LQAAVEKLLEAISETNTQLEHAKVTQTELmRESFRQKQEATESLhcLEELRERLQEESRAREQLAEELNKAESVIDGYSD 1889
Cdd:pfam19220   25 LKADFSQLIEPIEAILRELPQAKSRLLEL-EALLAQERAAYGKL--RRELAGLTRRLSAAEGELEELVARLAKLEAALRE 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1890 EKTLFERQ---IQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQllcrQREAMRAEAgpvEQQFLQETEKLMKekl 1966
Cdd:pfam19220  102 AEAAKEELrieLRDKTAQAEALERQLAAETEQNRALEEENKALREEAQ----AAEKALQRA---EGELATARERLAL--- 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1967 evqcqaekvrgdLQKQVKALEIDVEEQVSRFIELEQeKNAELTDLRQQSQALEKQLEKmrKFLDEQAidrEHERDVFQQE 2046
Cdd:pfam19220  172 ------------LEQENRRLQALSEEQAAELAELTR-RLAELETQLDATRARLRALEG--QLAAEQA---ERERAEAQLE 233

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2047 IQKLEHQLKavpriqpvSEHQAREVEQLTNHLkEKTDRcselLLSkeQLQRDIQERNEEIEKLECRVRELEQALLASaep 2126
Cdd:pfam19220  234 EAVEAHRAE--------RASLRMKLEALTARA-AATEQ----LLA--EARNQLRDRDEAIRAAERRLKEASIERDTL--- 295

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2127 fpkvedQKRSGAVEADPELSLEVQLQVER---DATDRKQ---KEITNLEEQLEQFREELENKNDEVQELLMQLEIQRkes 2200
Cdd:pfam19220  296 ------ERRLAGLEADLERRTQQFQEMQRaraELEERAEmltKALAAKDAALERAEERIASLSDRIAELTKRFEVER--- 366

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 1039770159 2201 ttrlqelqqenrlfkvieeqkeqiQDLETQIERLMSEREHEKKQR 2245
Cdd:pfam19220  367 ------------------------AALEQANRRLKEELQRERAER 387
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1871-2449 3.75e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 46.71  E-value: 3.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1871 EQLAEELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESD----QRRVEEER---QLLCRQREAM 1943
Cdd:pfam01576   22 QKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEIlhelESRLEEEEersQQLQNEKKKM 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1944 RAEAGPVEQQFLQET---EKLMKEKLEVQCQAEKVRGD----------LQKQVKALEIDVEEQVSRFIElEQEKNAELTD 2010
Cdd:pfam01576  102 QQHIQDLEEQLDEEEaarQKLQLEKVTTEAKIKKLEEDillledqnskLSKERKLLEERISEFTSNLAE-EEEKAKSLSK 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2011 LRQQSQALEKQLEkmrkfldeqaiDREHERDVFQQEIQKLEHQLKAvpriqpvsehqareveqltnHLKEKTDRCSELLL 2090
Cdd:pfam01576  181 LKNKHEAMISDLE-----------ERLKKEEKGRQELEKAKRKLEG--------------------ESTDLQEQIAELQA 229

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2091 SKEQLQRDIQERNEEIEKLECRVREleqallasaEPFPKVEDQKRSGAVEADpELSLEVQLQVERDATDRKQKEITNLEE 2170
Cdd:pfam01576  230 QIAELRAQLAKKEEELQAALARLEE---------ETAQKNNALKKIRELEAQ-ISELQEDLESERAARNKAEKQRRDLGE 299

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2171 QLEQFREELENKND--------------EVQELLMQLEIQRKESTTRLQELQQenRLFKVIEEQKEQIQdletQIERLMS 2236
Cdd:pfam01576  300 ELEALKTELEDTLDttaaqqelrskreqEVTELKKALEEETRSHEAQLQEMRQ--KHTQALEELTEQLE----QAKRNKA 373

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2237 EREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQREGARTlpedeesfkhQLDKVTAEKLVLEQQVETTNQVMTHMNNVLK 2316
Cdd:pfam01576  374 NLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEG----------QLQELQARLSESERQRAELAEKLSKLQSELE 443

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2317 EINFKMDQITQSLCNLNKECASneelpslpKESVHMTVHELGSDNLQPEDAPAQDVTKPLEKQTSLTRLQKSPEASRtQE 2396
Cdd:pfam01576  444 SVSSLLNEAEGKNIKLSKDVSS--------LESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAK-RN 514

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039770159 2397 IESLASSVGAKDVELTQCREQTETIQEQAQSETDRLQKKLTDLQRSLEKFAAA 2449
Cdd:pfam01576  515 VERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAA 567
CCCAP pfam15964
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ...
 1935-2325 3.87e-04

Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.


Pssm-ID: 435040 [Multi-domain]  Cd Length: 703  Bit Score: 46.44  E-value: 3.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1935 LLCRQREAMRAEAGpvEQQFLQETEKLMKEKLEVQCQAEKVRGDLqKQVKALEIDVEEQVSRFIELEQEKNAE----LTD 2010
Cdd:pfam15964  281 LKCAQHEAVLAQTH--TNVHMQTIERLTKERDDLMSALVSVRSSL-AEAQQRESSAYEQVKQAVQMTEEANFEktkaLIQ 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2011 LRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQK------------------LEHQLKAVPRIQPVSEHQAREVE 2072
Cdd:pfam15964  358 CEQLKSELERQKERLEKELASQQEKRAQEKEALRKEMKKereelgatmlalsqnvaqLEAQVEKVTREKNSLVSQLEEAQ 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2073 -QLTNHLKEKTDRCSEL--LLSKEQLQRDIQE------RNEEIEKLECRVRELEQALLASAEPFPKVEDQKRSGAVEADP 2143
Cdd:pfam15964  438 kQLASQEMDVTKVCGEMryQLNQTKMKKDEAEkehreyRTKTGRQLEIKDQEIEKLGLELSESKQRLEQAQQDAARAREE 517

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2144 ELSL-------EVQLQVERDATDRKQKEITN----LEEQLEQFREELENKndevqelLMQLEIQRKESTTRLQELQQENR 2212
Cdd:pfam15964  518 CLKLtellgesEHQLHLTRLEKESIQQSFSNeakaQALQAQQREQELTQK-------MQQMEAQHDKTVNEQYSLLTSQN 590

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2213 LFkvIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQREGARTLPEDEESFKHQLDK--- 2289
Cdd:pfam15964  591 TF--IAKLKEECCTLAKKLEEITQKSRSEVEQLSQEKEYLQDRLEKLQKRNEELEEQCVQHGRMHERMKQRLRQLDKhcq 668

                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 1039770159 2290 VTAEKLVleQQVETTNQVMTHMNNVLKEINFKMDQI 2325
Cdd:pfam15964  669 ATAQQLV--QLLSKQNQLFKERQNLTEEVQSLRSQV 702
46 PHA02562
endonuclease subunit; Provisional
 423-640 4.17e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.16  E-value: 4.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  423 QIVQMKQELINQhmsqieELKSQHKreMENTLKSDTNAAISKEQ------VNLMN---AAINELNVRLQETHAQKEELKG 493
Cdd:PHA02562   184 QTLDMKIDHIQQ------QIKTYNK--NIEEQRKKNGENIARKQnkydelVEEAKtikAEIEELTDELLNLVMDIEDPSA 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  494 ELGVVLGEKSALQSQSNDLLEEVRFLRE--QVQKARQTIAEQENRLSEARKSLSTV----EDLKAEIVAASE-------- 559
Cdd:PHA02562   256 ALNKLNTAAAKIKSKIEQFQKVIKMYEKggVCPTCTQQISEGPDRITKIKDKLKELqhslEKLDTAIDELEEimdefneq 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  560 SRKELELKHEAEITNYKIKLEmlekeknavlDRMAESQEAELERLRTQLLfSHEEELSKLKEDLE--VEHRINIEKLKDN 637
Cdd:PHA02562   336 SKKLLELKNKISTNKQSLITL----------VDKAKKVKAAIEELQAEFV-DNAEELAKLQDELDkiVKTKSELVKEKYH 404


                   ...
gi 1039770159  638 LGI 640
Cdd:PHA02562   405 RGI 407
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1808-2450 4.38e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.60  E-value: 4.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1808 SRLQAAVEKLLEAISETNTQLEHAKVTQTELMR-------ESFRQKQEATESLHCLEELRERLQEESRAR-EQLAEELNK 1879
Cdd:TIGR02169  247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKkikdlgeEEQLRVKEKIGELEAEIASLERSIAEKERElEDAEERLAK 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1880 AESVIDGYSDEKTLFERQIQEK-------TDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEAGPVEQ 1952
Cdd:TIGR02169  327 LEAEIDKLLAEIEELEREIEEErkrrdklTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKR 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1953 qflqETEKLMKEKLEVQCQAEKVRGDLQkqvkaleiDVEEQVSRFIELEQEKNAELTDLRQQSQALEKQLEKMRK--FLD 2030
Cdd:TIGR02169  407 ----ELDRLQEELQRLSEELADLNAAIA--------GIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQelYDL 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2031 EQAIDR-EHERDVFQQEIQKLEHQLKAVPRIQPVSehqAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQE-------- 2101
Cdd:TIGR02169  475 KEEYDRvEKELSKLQRELAEAEAQARASEERVRGG---RAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVaagnrlnn 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2102 ---RNEEIEKLECRVRELEQALLASAEPFPKVEDQKRSGA--------------VEADPELSLEVQ------LQVERDAT 2158
Cdd:TIGR02169  552 vvvEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSilsedgvigfavdlVEFDPKYEPAFKyvfgdtLVVEDIEA 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2159 DRKQKEI-------------------------------TNLEEQLEQFREELEnkndEVQELLMQLEIQRKESTTRLQEL 2207
Cdd:TIGR02169  632 ARRLMGKyrmvtlegelfeksgamtggsraprggilfsRSEPAELQRLRERLE----GLKRELSSLQSELRRIENRLDEL 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2208 QQEnrlfkvieeqkeqIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKLQqevvSTEQQREGARTlpedeesfkhQL 2287
Cdd:TIGR02169  708 SQE-------------LSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS----SLEQEIENVKS----------EL 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2288 DKVTAEklvLEQQVETTNQVMTHMNNVLKEINF-KMDQITQSLCNLNKECASNEelpslpkESVHMTVHELGSdnLQPED 2366
Cdd:TIGR02169  761 KELEAR---IEELEEDLHKLEEALNDLEARLSHsRIPEIQAELSKLEEEVSRIE-------ARLREIEQKLNR--LTLEK 828

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2367 APAQDVTKPLEKQTSLTRLQKspeASRTQEIESLASSVGAKDVELTQCREQTETIQEQA---QSETDRLQKKLTDLQRSL 2443
Cdd:TIGR02169  829 EYLEKEIQELQEQRIDLKEQI---KSIEKEIENLNGKKEELEEELEELEAALRDLESRLgdlKKERDELEAQLRELERKI 905


                   ....*..
gi 1039770159 2444 EKFAAAL 2450
Cdd:TIGR02169  906 EELEAQI 912
Nup88 pfam10168
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal ...
 2168-2360 4.38e-04

Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal two-thirds of the protein has no obvious structural motifs but is the region for binding to Nup98, one of the components of the nuclear pore. the C-terminal end is a predicted coiled-coil domain. Nup88 is overexpressed in tumour cells.


Pssm-ID: 462975 [Multi-domain]  Cd Length: 713  Bit Score: 46.19  E-value: 4.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2168 LEEQLEQFREELENKNDEVQEllmqlEIQRKESTTRLQELQQENRLfKVIEEQKEQIQDletQIERLmSEREHEKKQREE 2247
Cdd:pfam10168  537 LSRATQVFREEYLKKHDLARE-----EIQKRVKLLKLQKEQQLQEL-QSLEEERKSLSE---RAEKL-AEKYEEIKDKQE 606

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2248 EveqLTGVVEKLQQEVVSTEQqregarTLPEDEESFKhqldkvtaeklvleQQVETTNQVMTHMNNVLKEINFKMD-QIT 2326
Cdd:pfam10168  607 K---LMRRCKKVLQRLNSQLP------VLSDAEREMK--------------KELETINEQLKHLANAIKQAKKKMNyQRY 663

                          170       180       190
                   ....*....|....*....|....*....|....
gi 1039770159 2327 QSLCNLNKECASNEELPSLPKESVHMTVHELGSD 2360
Cdd:pfam10168  664 QIAKSQSIRKKSSLSLSEKQRKTIKEILKQLGSE 697
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 335-596 4.95e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.07  E-value: 4.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  335 DELLGGLHE----QLTQRNQEIQSLKLElgnsqqNERKCSEEIKELMRTVEE-LQKRNLKDSWLETSAVRRVE---QETQ 406
Cdd:PRK05771    19 DEVLEALHElgvvHIEDLKEELSNERLR------KLRSLLTKLSEALDKLRSyLPKLNPLREEKKKVSVKSLEeliKDVE 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  407 RKLSHLQAELDEMyGKQIVQMKQEL--INQHMSQIEELKS-----QHKREMENTLKSDtnAAISKEQVNLMNAAINELNV 479
Cdd:PRK05771    93 EELEKIEKEIKEL-EEEISELENEIkeLEQEIERLEPWGNfdldlSLLLGFKYVSVFV--GTVPEDKLEELKLESDVENV 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  480 RLqethaqKEELKGELGVVL-GEKSALQSQSnDLLEEVRFLREQVQ---KARQTIAEQENRLSEarkslstvedLKAEIV 555
Cdd:PRK05771   170 EY------ISTDKGYVYVVVvVLKELSDEVE-EELKKLGFERLELEeegTPSELIREIKEELEE----------IEKERE 232

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 1039770159  556 AASESRKELELKHEAEITNYKIKLEMlEKEKNAVLDRMAES 596
Cdd:PRK05771   233 SLLEELKELAKKYLEELLALYEYLEI-ELERAEALSKFLKT 272
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 280-862 5.12e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 46.20  E-value: 5.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  280 LQEKLRAFEMEKDRKIENLN-AKEIQEKQALIDELNTRVVEEEKKTVELKNKVTT-ADELLGGLH--EQLTQRNQEIQSL 355
Cdd:TIGR01612 1089 IKEKLKHYNFDDFGKEENIKyADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENyIDEIKAQINdlEDVADKAISNDDP 1168

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  356 KlELGNSQQN-------ERKCSEEIKELMRTVEELQK--------RNLKDSW---LETSAVRRVEQETQRKLSHLQAEld 417
Cdd:TIGR01612 1169 E-EIEKKIENivtkidkKKNIYDEIKKLLNEIAEIEKdktsleevKGINLSYgknLGKLFLEKIDEEKKKSEHMIKAM-- 1245

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  418 EMYGKQIVQMKQEliNQHMSQIEELKSQHKREME--NTLKSDTNAAISKEQVNLMNAA-INELNVRLQETHAQKE---EL 491
Cdd:TIGR01612 1246 EAYIEDLDEIKEK--SPEIENEMGIEMDIKAEMEtfNISHDDDKDHHIISKKHDENISdIREKSLKIIEDFSEESdinDI 1323

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  492 KGELGVVLGEKSALQSQSNDLLEEVRFLRE-----QVQKARQTIAEQENRLSEARKS----LSTVEDLKAEIVAASeSRK 562
Cdd:TIGR01612 1324 KKELQKNLLDAQKHNSDINLYLNEIANIYNilklnKIKKIIDEVKEYTKEIEENNKNikdeLDKSEKLIKKIKDDI-NLE 1402

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  563 ELELKHEAEITNYKIK--LEMLEKEKNAVLDRMAES----QEAELERLRTQLLFSHEEE--------LSKLKEDLEVEHR 628
Cdd:TIGR01612 1403 ECKSKIESTLDDKDIDecIKKIKELKNHILSEESNIdtyfKNADENNENVLLLFKNIEMadnksqhiLKIKKDNATNDHD 1482

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  629 INIEKLKDNL--GIHYKQQID--GLQNEMNRKM-ESMQCETDNLITQQNQLILEN--SKLRDLQECLVNSKSEEMNLQIN 701
Cdd:TIGR01612 1483 FNINELKEHIdkSKGCKDEADknAKAIEKNKELfEQYKKDVTELLNKYSALAIKNkfAKTKKDSEIIIKEIKDAHKKFIL 1562

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  702 ELQKEIEILKQEEKEKGTLEQEVQE----------LQLKTEQLEKQLKeKEDDLQEKCaqldaeNNILKEEKRVlEDKLK 771
Cdd:TIGR01612 1563 EAEKSEQKIKEIKKEKFRIEDDAAKndksnkaaidIQLSLENFENKFL-KISDIKKKI------NDCLKETESI-EKKIS 1634

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  772 MYSPSEQE-ERSIAVDPSTSKSAdsrWQKEVAMLRKETEDLQQQCLYLNEEIEKQRNTFAFAEKNFEVNYQELQREYTCL 850
Cdd:TIGR01612 1635 SFSIDSQDtELKENGDNLNSLQE---FLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIA 1711

                          650
                   ....*....|..
gi 1039770159  851 LKirDDLEATQT 862
Cdd:TIGR01612 1712 NK--EEIESIKE 1721
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 1923-2292 5.13e-04

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 46.33  E-value: 5.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1923 ESDQRRVEEERQLLCRQREAMRaeagpvEQQFLQETEKLMKE---KLEVQCQAEKVRGDLQKQVKALEIDV-EEQVSRFI 1998
Cdd:PRK10246   223 ASLQVLTDEEKQLLTAQQQQQQ------SLNWLTRLDELQQEasrRQQALQQALAAEEKAQPQLAALSLAQpARQLRPHW 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1999 ELEQEKNAELTDLRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEHQLKAVPRIQPVSEHQAREVEQLTNHL 2078
Cdd:PRK10246   297 ERIQEQSAALAHTRQQIEEVNTRLQSTMALRARIRHHAAKQSAELQAQQQSLNTWLAEHDRFRQWNNELAGWRAQFSQQT 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2079 KEKtdrcSELLLSKEQLQRDIQERNEEIE-KLECRVRELEQALLASAEPFPKvedQKRSGAVEAD--PELSLEVQLQver 2155
Cdd:PRK10246   377 SDR----EQLRQWQQQLTHAEQKLNALPAiTLTLTADEVAAALAQHAEQRPL---RQRLVALHGQivPQQKRLAQLQ--- 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2156 DATDRKQKEITNLEEQLEQFREELENKNDEVQELlmqleiqrkesttrlqelqqenrlfKVIEEQKEQIQDLETQIERLM 2235
Cdd:PRK10246   447 VAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADV-------------------------KTICEQEARIKDLEAQRAQLQ 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2236 S-------------------------------EREHEKKQREEEVEQLTGVVEKLQQEVvstEQQREGARTLPEDEESFK 2284
Cdd:PRK10246   502 AgqpcplcgstshpaveayqalepgvnqsrldALEKEVKKLGEEGAALRGQLDALTKQL---QRDESEAQSLRQEEQALT 578


                   ....*...
gi 1039770159 2285 HQLDKVTA 2292
Cdd:PRK10246   579 QQWQAVCA 586
PTZ00121 PTZ00121
MAEBL; Provisional
 5-578 5.16e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.29  E-value: 5.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159    5 ERQRKLAAGKAKLARFRQRKAQYDGDIPKKQKKKRTSSSKHDSSLHTDQQSGELCSESSQRVDLAgNPDCSGPERKHGQV 84
Cdd:PTZ00121  1332 DAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA-KKKAEEDKKKADEL 1410

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159   85 FSAEPESEISTTADECSSEINGCNSVMK----PRKPTDPLREEEFSLDDSSSEQGAQSSQTCLQMVEKelAEKQHDIEEL 160
Cdd:PTZ00121  1411 KKAAAAKKKADEAKKKAEEKKKADEAKKkaeeAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKK--AEEAKKADEA 1488

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  161 TQELEEMR-----ASFGTEGLKQLQEFEAAIKQRDGiitqltanlQQARREKDDTMVEFLELTEQSQKLQiqfqHLQANE 235
Cdd:PTZ00121  1489 KKKAEEAKkkadeAKKAAEAKKKADEAKKAEEAKKA---------DEAKKAEEAKKADEAKKAEEKKKAD----ELKKAE 1555

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  236 TLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEMEKDRKIENLNAKEIQEKQA-----LI 310
Cdd:PTZ00121  1556 ELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAeeekkKV 1635

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  311 DELNTRVVEEEKKTVELKNkvttADELLGGLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEIK---ELMRTVEELQKRN 387
Cdd:PTZ00121  1636 EQLKKKEAEEKKKAEELKK----AEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKkeaEEAKKAEELKKKE 1711

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  388 LKDSwLETSAVRRVEQETQRKLSHLQAELDEMYGKQIVQMKQElinQHMSQIEELKSQHKREMENTLKsDTNAAISKEQV 467
Cdd:PTZ00121  1712 AEEK-KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDE---EEKKKIAHLKKEEEKKAEEIRK-EKEAVIEEELD 1786

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  468 NLMNAAINELNVRLQETHAQKEEL-----KGELgVVLGEKSALQSQ-------SNDLLEEVRFLREQVQKARQTIAEQEN 535
Cdd:PTZ00121  1787 EEDEKRRMEVDKKIKDIFDNFANIieggkEGNL-VINDSKEMEDSAikevadsKNMQLEEADAFEKHKFNKNNENGEDGN 1865

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1039770159  536 RLSEARKSLSTVEDLKAEIVAASESRKELELKHEAEITNYKIK 578
Cdd:PTZ00121  1866 KEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMA 1908
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
471-882 5.31e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 5.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  471 NAAINELNVRLQETHAQKEELKGELGVVLGEKSALqsqsnDLLEEVRFLREQVQKARQTIAEQENRLSEARKSLSTVEDL 550
Cdd:COG4717     87 EEEYAELQEELEELEEELEELEAELEELREELEKL-----EKLLQLLPLYQELEALEAELAELPERLEELEERLEELREL 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  551 KAEIVAASESRKELE-----------LKHEAEITNYKIKLEMLEKEKNAVLDRMAESQEaELERLRTQLlfsheEELSKL 619
Cdd:COG4717    162 EEELEELEAELAELQeeleelleqlsLATEEELQDLAEELEELQQRLAELEEELEEAQE-ELEELEEEL-----EQLENE 235

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  620 KEDLEVEHRINIEKL-------------KDNLGIHYKQQIDGLQ-----------NEMNRKMESMQCETDNLITQQNQLI 675
Cdd:COG4717    236 LEAAALEERLKEARLllliaaallallgLGGSLLSLILTIAGVLflvlgllallfLLLAREKASLGKEAEELQALPALEE 315

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  676 LENSKLRDLQECLVNSKSEEmNLQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQ---LEKQLKEKEDDLQEKCAQL 752
Cdd:COG4717    316 LEEEELEELLAALGLPPDLS-PEELLELLDRIEELQELLREAEELEEELQLEELEQEIaalLAEAGVEDEEELRAALEQA 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  753 DAENNiLKEEKRVLEDKLKMYSPSEQEERSiAVDPSTSKSADSRWQKEVAMLRKETEDLQQQCLYLNEEIEKQRNTFAFA 832
Cdd:COG4717    395 EEYQE-LKEELEELEEQLEELLGELEELLE-ALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELA 472

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1039770159  833 EKNFEVNY-----QELQREYTCLLKIRDDLEATQTKQALEYESKLRALEEELLSK 882
Cdd:COG4717    473 ELLQELEElkaelRELAEEWAALKLALELLEEAREEYREERLPPVLERASEYFSR 527
PRK01156 PRK01156
chromosome segregation protein; Provisional
 694-988 5.80e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.05  E-value: 5.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  694 EEMNLQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDaENNILKEEKRVLEDKLKM- 772
Cdd:PRK01156   190 EKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLED-MKNRYESEIKTAESDLSMe 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  773 ------YSPSEQEERSIAVDPSTSKSADSRwqkEVAMLRKETEDLQQQCLYLNEEIEKQRNTFAFAE--KNFEVNYQELQ 844
Cdd:PRK01156   269 leknnyYKELEERHMKIINDPVYKNRNYIN---DYFKYKNDIENKKQILSNIDAEINKYHAIIKKLSvlQKDYNDYIKKK 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  845 REYTCLLKIRDDLEATQTKqaleYESKLRALEEelLSKRGNPAAPKGKSSGIFPSETLEIGEVvekDTTELMEKLEVTKR 924
Cdd:PRK01156   346 SRYDDLNNQILELEGYEMD----YNSYLKSIES--LKKKIEEYSKNIERMSAFISEILKIQEI---DPDAIKKELNEINV 416

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039770159  925 EKLELSEKVSglseqlkqthctinSLSAEVRALKQEKEqlllrcgelELLANPSGTENAAVCPV 988
Cdd:PRK01156   417 KLQDISSKVS--------------SLNQRIRALRENLD---------ELSRNMEMLNGQSVCPV 457
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1806-2350 6.10e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.05  E-value: 6.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1806 ISSRLQAAVEKLLEAISETNTQLEHAKVTQTELMR---ESFRQKQEATESLHCLEELRERLQEESRAREQLAEELNKAES 1882
Cdd:PRK01156   212 SHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSledMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVY 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1883 VIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNN---RLQELESDQRRVEE---ERQLLCRQREAMRAEAGPVeQQFLQ 1956
Cdd:PRK01156   292 KNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAiikKLSVLQKDYNDYIKkksRYDDLNNQILELEGYEMDY-NSYLK 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1957 ETEKLMKEKLEVQCQAEKVRGDLQKQVKALEIDVEEQVSRFIELE---QEKNAELTDLRQQSQALEKQLEKMRK---FLD 2030
Cdd:PRK01156   371 SIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINvklQDISSKVSSLNQRIRALRENLDELSRnmeMLN 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2031 EQAIDREHERDVFQQEIQKL-EHQLKAVPRIQPVSEHQAREVEQLTN---HLKEKTDRcsellLSKEQLQRDIQERNEeI 2106
Cdd:PRK01156   451 GQSVCPVCGTTLGEEKSNHIiNHYNEKKSRLEEKIREIEIEVKDIDEkivDLKKRKEY-----LESEEINKSINEYNK-I 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2107 EKLECRVRELEQALLASAEPFPKVE---DQKRSGAVE-ADPELSLEVQLQVERDATDrkqkeITNLEEQLEQFREELENK 2182
Cdd:PRK01156   525 ESARADLEDIKIKINELKDKHDKYEeikNRYKSLKLEdLDSKRTSWLNALAVISLID-----IETNRSRSNEIKKQLNDL 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2183 NDEVQELLMQLEIQRKESTTRLQELQQENRLFkviEEQKEQIQDLETQIERLMSEREHEKKQREEEVEqltgvVEKLQQE 2262
Cdd:PRK01156   600 ESRLQEIEIGFPDDKSYIDKSIREIENEANNL---NNKYNEIQENKILIEKLRGKIDNYKKQIAEIDS-----IIPDLKE 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2263 VVSTEQQREgartlpEDEESFKHQLDKVTAEKLVLEQQVETTNQVMTHMNNVLKEINF---KMDQITQSLCNLN--KECA 2337
Cdd:PRK01156   672 ITSRINDIE------DNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINEtleSMKKIKKAIGDLKrlREAF 745

                          570
                   ....*....|...
gi 1039770159 2338 SNEELPSLPKESV 2350
Cdd:PRK01156   746 DKSGVPAMIRKSA 758
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1776-2189 6.40e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.80  E-value: 6.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1776 EEGAELSQRLVRSGFAgpviDPENEELMLNISSrLQAAVEKLLEAISETNTQLEHAKvTQTELMRESFRQKQEATESLHC 1855
Cdd:PRK02224   290 ELEEERDDLLAEAGLD----DADAEAVEARREE-LEDRDEELRDRLEECRVAAQAHN-EEAESLREDADDLEERAEELRE 363

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1856 LEELRERLQEESR-AREQLAEELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQR----RVE 1930
Cdd:PRK02224   364 EAAELESELEEAReAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRtareRVE 443

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1931 EERQLL-----------------------CRQR-EAMRAEAGPVEQQFLQETEKLmkEKLEVQCQAEKVRGDLQKQVKAL 1986
Cdd:PRK02224   444 EAEALLeagkcpecgqpvegsphvetieeDRERvEELEAELEDLEEEVEEVEERL--ERAEDLVEAEDRIERLEERREDL 521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1987 EIDVEEQVSRfIELEQEKNAELtdlRQQSQALEKQLEKMRkfldEQAIDREHERDVFQQEIQKLEHQLKAVP-RIQpvse 2065
Cdd:PRK02224   522 EELIAERRET-IEEKRERAEEL---RERAAELEAEAEEKR----EAAAEAEEEAEEAREEVAELNSKLAELKeRIE---- 589

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2066 hQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQALLASAepfpkVED--QKRSGAVEADP 2143
Cdd:PRK02224   590 -SLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEAR-----IEEarEDKERAEEYLE 663

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*....
gi 1039770159 2144 ELslEVQLQVERDATDRKQKEITNLE---EQLEQFREELENKNDEVQEL 2189
Cdd:PRK02224   664 QV--EEKLDELREERDDLQAEIGAVEnelEELEELRERREALENRVEAL 710
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 2012-2469 8.30e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.34  E-value: 8.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2012 RQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEHQLKavpriqpvsehQAREVEQLTNHLKEKTDRCSELLLS 2091
Cdd:TIGR00618  186 FAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELK-----------HLREALQQTQQSHAYLTQKREAQEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2092 KEQLQRDIQERNEEIEKLECRVRELEQAllasaepfpkvedQKRsgaveadpelsLEVQLQVERDATDrkQKEITNLEEQ 2171
Cdd:TIGR00618  255 QLKKQQLLKQLRARIEELRAQEAVLEET-------------QER-----------INRARKAAPLAAH--IKAVTQIEQQ 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2172 LEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENRLFK---VIEEQKEQIQDLETQIERLMSEREHEKKQReee 2248
Cdd:TIGR00618  309 AQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSqeiHIRDAHEVATSIREISCQQHTLTQHIHTLQ--- 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2249 vEQLTGVVEKLQQEVVSTEQ-QREGARTLPEDEESFKHQLDKVTAEK---------LVLEQQVETTNQVMTHMNNVLKEI 2318
Cdd:TIGR00618  386 -QQKTTLTQKLQSLCKELDIlQREQATIDTRTSAFRDLQGQLAHAKKqqelqqryaELCAAAITCTAQCEKLEKIHLQES 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2319 NFKMDQITQSLCNLNKECASNEELPS---------------LPKESVHMTVHELGSDNLQPEDAPAQ---DVTKPLEKQT 2380
Cdd:TIGR00618  465 AQSLKEREQQLQTKEQIHLQETRKKAvvlarllelqeepcpLCGSCIHPNPARQDIDNPGPLTRRMQrgeQTYAQLETSE 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2381 SLTRLQKSPEASRTQEIESLASSVGAKDVELTQCREQTETIQEQAQSETDRLQK---KLTDLQRSLEKFAAALVSQVQME 2457
Cdd:TIGR00618  545 EDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDlteKLSEAEDMLACEQHALLRKLQPE 624

                          490
                   ....*....|..
gi 1039770159 2458 AAQEYVPFHQEK 2469
Cdd:TIGR00618  625 QDLQDVRLHLQQ 636
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2078-2303 8.32e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.42  E-value: 8.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2078 LKEKTDRCSELLLSKEQLQRDIQERNEEIEK---------LECRVRELEQALLASAEPFPKVEDQKRSgAVEADPELSLE 2148
Cdd:PRK02224   164 LEEYRERASDARLGVERVLSDQRGSLDQLKAqieekeekdLHERLNGLESELAELDEEIERYEEQREQ-ARETRDEADEV 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2149 VQLQVE-RDATDRKQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENRLFKVIEEQKEQIQDL 2227
Cdd:PRK02224   243 LEEHEErREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDR 322

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770159 2228 ETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEvvsTEQQREGARTLPEDEESFKHQLDKVTAEKLVLEQQVET 2303
Cdd:PRK02224   323 DEELRDRLEECRVAAQAHNEEAESLREDADDLEER---AEELREEAAELESELEEAREAVEDRREEIEELEEEIEE 395
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1920-2259 8.35e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 45.60  E-value: 8.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1920 QELESDQRRVEE----ERQLLCRQREAMRAEAGPVEQQFLQETEKLMKEKlevqcQAEKVRGDLQKQVKALEIDVEEQVS 1995
Cdd:pfam12128  600 EELRERLDKAEEalqsAREKQAAAEEQLVQANGELEKASREETFARTALK-----NARLDLRRLFDEKQSEKDKKNKALA 674

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1996 RFIeleQEKNAELTDLRQQSQALEKQLEKMRKFLDEQAidREHeRDVFQQEIQKLEHQLKAvpRIQPVSEHQAREVEQLT 2075
Cdd:pfam12128  675 ERK---DSANERLNSLEAQLKQLDKKHQAWLEEQKEQK--REA-RTEKQAYWQVVEGALDA--QLALLKAAIAARRSGAK 746

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2076 NHLKE-KTDRCSELLlskeqlQRDIQErnEEIEKLECRVRELEQallasaepfpKVEDQKRSGAVEADPELSLEVQLQVE 2154
Cdd:pfam12128  747 AELKAlETWYKRDLA------SLGVDP--DVIAKLKREIRTLER----------KIERIAVRRQEVLRYFDWYQETWLQR 808

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2155 RDatdRKQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENRLFKVI-------------EEQK 2221
Cdd:pfam12128  809 RP---RLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEmsklatlkedansEQAQ 885

                          330       340       350
                   ....*....|....*....|....*....|....*...
gi 1039770159 2222 EQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKL 2259
Cdd:pfam12128  886 GSIGERLAQLEDLKLKRDYLSESVKKYVEHFKNVIADH 923
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 137-828 8.62e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.42  E-value: 8.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  137 QSSQTCLQMVEKELAEKQHDIEELTQELEEMRASFgTEGLKQLQEFEAAIKQRDGIITQLTANLQ---QARREKDDTMVE 213
Cdd:TIGR00606  230 EAQLESSREIVKSYENELDPLKNRLKEIEHNLSKI-MKLDNEIKALKSRKKQMEKDNSELELKMEkvfQGTDEQLNDLYH 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  214 FLELTEQSQKLQIQFQHLQANETLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEMEKDR 293
Cdd:TIGR00606  309 NHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFS 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  294 KIENLNA----KEIQEKQA-----LIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQ 364
Cdd:TIGR00606  389 ERQIKNFhtlvIERQEDEAktaaqLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEG 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  365 NERKCSEEIKELMRTVEELQK----RNLKDSWLETSAVRRVEQETQRKLSHLQAELDEMYGKQIVQMKQELINQHMS--- 437
Cdd:TIGR00606  469 SSDRILELDQELRKAERELSKaeknSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMdkd 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  438 -QIEELKSQHKREMENTLK--------SDTNAAISKEqVNLMNAAINELNVRLQETHAQKEELKGELGVVLGEKSALQSQ 508
Cdd:TIGR00606  549 eQIRKIKSRHSDELTSLLGyfpnkkqlEDWLHSKSKE-INQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDK 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  509 ------SNDLLEEVRFLREQVQKAR--------------QTIAEQENRLSEARKSLSTVEDLKAEIVAASESRKELELKH 568
Cdd:TIGR00606  628 lfdvcgSQDEESDLERLKEEIEKSSkqramlagatavysQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLA 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  569 EAEITNYKIKLEMLEKEKNAVLDrMAESQEAELERLrtqllfshEEELSKLKEDLEVEHRiNIEKLKDNLGIHYKQqidg 648
Cdd:TIGR00606  708 PDKLKSTESELKKKEKRRDEMLG-LAPGRQSIIDLK--------EKEIPELRNKLQKVNR-DIQRLKNDIEEQETL---- 773

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  649 LQNEMNRKMESMQCETDNLITQQNQLILENSKlRDLQECLVNSKSEEMNLQINELQKEIEilkQEEKEKGTLEQEVQELQ 728
Cdd:TIGR00606  774 LGTIMPEEESAKVCLTDVTIMERFQMELKDVE-RKIAQQAAKLQGSDLDRTVQQVNQEKQ---EKQHELDTVVSKIELNR 849

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  729 LKTEqlekqlkekedDLQEKCAQLDAENNILKEEKRVLEDKLKMYSPSEQEERSIAVDPSTSKSADSRWQKEVAMLRKET 808
Cdd:TIGR00606  850 KLIQ-----------DQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFL 918

                          730       740
                   ....*....|....*....|
gi 1039770159  809 EDLQQQclylNEEIEKQRNT 828
Cdd:TIGR00606  919 EKDQQE----KEELISSKET 934
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1872-2338 9.39e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 45.17  E-value: 9.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1872 QLAEELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRV-------EEERQLLCRQREAMR 1944
Cdd:pfam01576  619 RYAEERDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVgknvhelERSKRALEQQVEEMK 698

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1945 AEAGPVEQQfLQETEKlMKEKLEVQCQAEKVRGDlqKQVKALEIDVEEQVSRFIELEQEKNAELTDLRQQ-SQAL--EKQ 2021
Cdd:pfam01576  699 TQLEELEDE-LQATED-AKLRLEVNMQALKAQFE--RDLQARDEQGEEKRRQLVKQVRELEAELEDERKQrAQAVaaKKK 774

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2022 LEKMRKFLDEQAIDREHERDVFQQEIQKLEHQLKAVPRiQPVSEHQAREveQLTNHLKEKTDRCSELLLSKEQLQRDIQE 2101
Cdd:pfam01576  775 LELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQR-ELEEARASRD--EILAQSKESEKKLKNLEAELLQLQEDLAA 851

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2102 RNEEIEKLECRVRELEQALLASAEPFPKVEDQKRSgaVEADPElSLEVQLQVERDATDRKQKEITNLEEQLEQFREELEN 2181
Cdd:pfam01576  852 SERARRQAQQERDELADEIASGASGKSALQDEKRR--LEARIA-QLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAA 928

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2182 KNDEVQEL---LMQLEIQRKESTTRLQELQQEnrlfkVIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEK 2258
Cdd:pfam01576  929 ERSTSQKSesaRQQLERQNKELKAKLQEMEGT-----VKSKFKSSIAALEAKIAQLEEQLEQESRERQAANKLVRRTEKK 1003

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2259 LQQEVVSTEQQREGArtlpedeESFKHQLDKVTAEKLVLEQQVETTNQVMTHMNNVLKEINFKMDQITQSLCNLNKECAS 2338
Cdd:pfam01576 1004 LKEVLLQVEDERRHA-------DQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVST 1076
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1867-2081 9.53e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 9.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1867 SRAREQLAEELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAE 1946
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1947 agpveqqfLQETEKLMKEKLEVQCQAEKVR-----------GDLQKQVKALEIDVEEQVSRFIELEQEKnAELTDLRQQS 2015
Cdd:COG4942     99 --------LEAQKEELAELLRALYRLGRQPplalllspedfLDAVRRLQYLKYLAPARREQAEELRADL-AELAALRAEL 169

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770159 2016 QALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEHQLKAVPRIQPVSEHQAREVEQLTNHLKEK 2081
Cdd:COG4942    170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 652-964 1.02e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 1.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  652 EMNRKMESMQCETDNLITQQNQLILENSKLRDLQECLVNSKSEEMNLQINELQKEIEILKQEEKEKGTLEQEVQELQLKT 731
Cdd:TIGR02169  181 EVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEI 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  732 EQLEKQLKEKEDDLQEKCAQLDAENNilKEEKRVLEDKLKMYSPSEQEERSIAVDPSTSKSADSRWQKEVAMLRKETEDL 811
Cdd:TIGR02169  261 SELEKRLEEIEQLLEELNKKIKDLGE--EEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEI 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  812 QQqclyLNEEIEKQRntfafaeknfeVNYQELQREYTCLLKIRDDLEAtqtkQALEYESKLRALEEELLSKRgnpaapkg 891
Cdd:TIGR02169  339 EE----LEREIEEER-----------KRRDKLTEEYAELKEELEDLRA----ELEEVDKEFAETRDELKDYR-------- 391

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039770159  892 kssgifpsetleigevvekdttelmEKLEVTKREKLELSEKVSGLSEQLKQTHCTINSLSAEVRALKQEKEQL 964
Cdd:TIGR02169  392 -------------------------EKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINEL 439
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
146-634 1.07e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 1.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  146 VEKELAEKQHDIEELTQELEEMRAsfgTEGLKQLQEFEAAIKQRDGIITQLTANLQQARREKDD---TMVEFLELTEQSQ 222
Cdd:PRK02224   178 VERVLSDQRGSLDQLKAQIEEKEE---KDLHERLNGLESELAELDEEIERYEEQREQARETRDEadeVLEEHEERREELE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  223 KLQIQFQHLQAN--------ETLQN--STLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEMEKD 292
Cdd:PRK02224   255 TLEAEIEDLRETiaetererEELAEevRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECR 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  293 RKIENLNaKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNS---------- 362
Cdd:PRK02224   335 VAAQAHN-EEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDApvdlgnaedf 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  363 ----QQNERKCSEEIKELMRTVEELQKRNLKDSWL-------------ETSAVRRVEQETQRKLSHLQAELDEmygkqiV 425
Cdd:PRK02224   414 leelREERDELREREAELEATLRTARERVEEAEALleagkcpecgqpvEGSPHVETIEEDRERVEELEAELED------L 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  426 QMKQELINQHMSQIEELKSQHKRemenTLKSDTNAAISKEQVNLMNAAINELNVRLQETHAQKEELKGELGVVLGEKSAL 505
Cdd:PRK02224   488 EEEVEEVEERLERAEDLVEAEDR----IERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  506 QSQSNDLLEEVRFL----------REQVQKARQTIAEQEN------RLSEARKSLSTVEDLKAEIVAA-SESRKELELKH 568
Cdd:PRK02224   564 EEEAEEAREEVAELnsklaelkerIESLERIRTLLAAIADaedeieRLREKREALAELNDERRERLAEkRERKRELEAEF 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  569 EAE---------------ITNYKIKLEMLEKEKNAVLDR--MAESQEAELERLRTQL------------LFSHEEELSKL 619
Cdd:PRK02224   644 DEArieearedkeraeeyLEQVEEKLDELREERDDLQAEigAVENELEELEELRERRealenrvealeaLYDEAEELESM 723

                          570
                   ....*....|....*.
gi 1039770159  620 KEDLEVEHRI-NIEKL 634
Cdd:PRK02224   724 YGDLRAELRQrNVETL 739
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1915-2269 1.14e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 44.81  E-value: 1.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1915 MNNRLQELESDQRRVEEERQLLCRQREAMRAEAGPVEQQFlqeteKLMKEKLEVQCQAEKVrgdLQKQVKALEIDVEEQV 1994
Cdd:pfam10174  287 MKNKIDQLKQELSKKESELLALQTKLETLTNQNSDCKQHI-----EVLKESLTAKEQRAAI---LQTEVDALRLRLEEKE 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1995 SrfieLEQEKNAELTDLRQQSQALEKQLEKMRKFLDEqaidREHERDVFQQEIQKLEHQLKAVPR--------------- 2059
Cdd:pfam10174  359 S----FLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDV----KERKINVLQKKIENLQEQLRDKDKqlaglkervkslqtd 430

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2060 ---------------------IQPVSEHQAR-------EVEQLTNHLKEKTDRCSEL---LLSKEQLQRDIQER----NE 2104
Cdd:pfam10174  431 ssntdtalttleealsekeriIERLKEQRERedrerleELESLKKENKDLKEKVSALqpeLTEKESSLIDLKEHasslAS 510

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2105 EIEKLECRVRELEQALLASAEPFPKVEDQKRSG-----AVEADPELS-----LEVQLQVERDATDRKQKEITNLEEQLEQ 2174
Cdd:pfam10174  511 SGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAhnaeeAVRTNPEINdrirlLEQEVARYKEESGKAQAEVERLLGILRE 590

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2175 FREELENKNDEVQELLMQLEIQRKESTTRLQELQQENRlfkviEEQKEQIQDLEtqiERLMSEREHEKKQREEEVEQLTG 2254
Cdd:pfam10174  591 VENEKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQ-----EMKKKGAQLLE---EARRREDNLADNSQQLQLEELMG 662

                          410
                   ....*....|....*
gi 1039770159 2255 VVEKLQQEVVSTEQQ 2269
Cdd:pfam10174  663 ALEKTRQELDATKAR 677
PRK01156 PRK01156
chromosome segregation protein; Provisional
 146-722 1.35e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 44.89  E-value: 1.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  146 VEKELAEKQHDIEELTQELEEMRASFgTEGLKQLQEFEAAIKQRDGIITQLTANLQQARREKDDTMVEFLELTEQSQKLQ 225
Cdd:PRK01156   188 LEEKLKSSNLELENIKKQIADDEKSH-SITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLS 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  226 IQfqhLQANETLQNST--LSRTATDLLQAKRQ----IFTQQQQLQDYQKKEEDLQAQISFLQEKLR-AFEMEKDRkienl 298
Cdd:PRK01156   267 ME---LEKNNYYKELEerHMKIINDPVYKNRNyindYFKYKNDIENKKQILSNIDAEINKYHAIIKkLSVLQKDY----- 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  299 naKEIQEKQALIDELNTRVVEeekktvelknkvttadelLGGLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEIKELMR 378
Cdd:PRK01156   339 --NDYIKKKSRYDDLNNQILE------------------LEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  379 ----TVEELQKRnlkdswleTSAVRRVEQETQRKLSHLQAELDEMYGKQI-VQMKQELINQHM------SQIEELKSQHK 447
Cdd:PRK01156   399 iqeiDPDAIKKE--------LNEINVKLQDISSKVSSLNQRIRALRENLDeLSRNMEMLNGQSvcpvcgTTLGEEKSNHI 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  448 REMENtlksdtnaaiskEQVNLMNAAINELNVRLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKAR 527
Cdd:PRK01156   471 INHYN------------EKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKIESARADLEDIKIKI 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  528 QTIAEQENRLSEARKSLST--VEDLKAEivaASESRKELELKHEAEITNYKIKLEMLEKEKNAVLDRMAE--SQEAELER 603
Cdd:PRK01156   539 NELKDKHDKYEEIKNRYKSlkLEDLDSK---RTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEieIGFPDDKS 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  604 LRTQLLFSHEEELSKL--KEDLEVEHRINIEKLKDNLGiHYKQQIDGL------QNEMNRKMESMQCETDNLITQQNQLI 675
Cdd:PRK01156   616 YIDKSIREIENEANNLnnKYNEIQENKILIEKLRGKID-NYKKQIAEIdsiipdLKEITSRINDIEDNLKKSRKALDDAK 694

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1039770159  676 LENSKLRDLQECLVnSKSEEMNLQINELQKEIEILKQEEKEKGTLEQ 722
Cdd:PRK01156   695 ANRARLESTIEILR-TRINELSDRINDINETLESMKKIKKAIGDLKR 740
COG5022 COG5022
Myosin heavy chain [General function prediction only];
291-727 1.53e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 44.68  E-value: 1.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  291 KDRKIENLNAKE---IQEKQALIDELNTRVVEEEKKTVELKNKVTTADEllggLHEQLTQRNQEIQSLKLELGNSQQNER 367
Cdd:COG5022    848 IQKFGRSLKAKKrfsLLKKETIYLQSAQRVELAERQLQELKIDVKSISS----LKLVNLELESEIIELKKSLSSDLIENL 923

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  368 KC-SEEIKELMRTVEELQKRNLKDSWLETSAVRRVEQETQRKLSHLQAELDEMYgkqivQMKQELINQHMSQIEELKsQH 446
Cdd:COG5022    924 EFkTELIARLKKLLNNIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEYEDLL-----KKSTILVREGNKANSELK-NF 997

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  447 KREMENTLKSDTNAAISKEQVNLMNAAINELNVRLQETHAQKEELKGELGvvlgeksaLQSQSNDLLEEVRFLREQVqKA 526
Cdd:COG5022    998 KKELAELSKQYGALQESTKQLKELPVEVAELQSASKIISSESTELSILKP--------LQKLKGLLLLENNQLQARY-KA 1068

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  527 RQTIAEQENRLSEARKSLSTVEDLKAEIVAASESRKELELKHEAEITNyKIKLEMLekeKNAVLDRMAESQEAELERLR- 605
Cdd:COG5022   1069 LKLRRENSLLDDKQLYQLESTENLLKTINVKDLEVTNRNLVKPANVLQ-FIVAQMI---KLNLLQEISKFLSQLVNTLEp 1144

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  606 -TQLLFSHEEELSKLKEDLEVEHRINIEKLKDNLGIH------YKQQIDGLQNEMNRKMESMQCETD------------- 665
Cdd:COG5022   1145 vFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRlyqsalYDEKSKLSSSEVNDLKNELIALFSkifsgwprgdklk 1224

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039770159  666 ------NLITQQNQLILENSKLRDLQECLVNSKSEEMNLQINELQKEIEILK-QEEKEKGTLEQEVQEL 727
Cdd:COG5022   1225 klisegWVPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKlEEEVLPATINSLLQYI 1293
mukB PRK04863
chromosome partition protein MukB;
1971-2271 1.56e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.56  E-value: 1.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1971 QAEKVRGDLQKQVKALEIDVEEQVSRFIELEQEKNAElTDLRQQSQALEKQLEKMRKFLDEQ-AIDReherdvFQQEIQK 2049
Cdd:PRK04863   287 EALELRRELYTSRRQLAAEQYRLVEMARELAELNEAE-SDLEQDYQAASDHLNLVQTALRQQeKIER------YQADLEE 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2050 LEHQLKAVpriQPVSEHQAREVEQLTNHLKEKTDRCSELllsKEQL----QR-DIQER-----NEEIEKLEcRVRELEQA 2119
Cdd:PRK04863   360 LEERLEEQ---NEVVEEADEQQEENEARAEAAEEEVDEL---KSQLadyqQAlDVQQTraiqyQQAVQALE-RAKQLCGL 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2120 LLASAEPFPKVEDQKRSGAVEADPE-LSLEVQLQVERDATDRKQKEITNL---------EEQLEQFREELENKNDEVQEL 2189
Cdd:PRK04863   433 PDLTADNAEDWLEEFQAKEQEATEElLSLEQKLSVAQAAHSQFEQAYQLVrkiagevsrSEAWDVARELLRRLREQRHLA 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2190 --LMQLEIQRKESTTRLQELQQENRLFKVIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEVVSTE 2267
Cdd:PRK04863   513 eqLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQ 592


                   ....
gi 1039770159 2268 QQRE 2271
Cdd:PRK04863   593 ARIQ 596
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2159-2464 1.80e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.29  E-value: 1.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2159 DRKQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRkESTTRLQELQQENRLFKV---------IEEQKE----QIQ 2225
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRER-EKAERYQALLKEKREYEGyellkekeaLERQKEaierQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2226 DLE---TQIERLMSEREHEKKQREEEVEQLTGVVEKL--------QQEVVSTEQQREGART-----------LPEDEESF 2283
Cdd:TIGR02169  248 SLEeelEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeeqlrvKEKIGELEAEIASLERsiaekereledAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2284 KHQLDKVTAEKLVLEQQVETTNQVMTHMNNVLKEINFKMDQITQSLCNLNKECASNEELPSLPKESVHMTVHELGSdnLQ 2363
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINE--LK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2364 PEDAPAQDVTKPLEKQTSLTRLQ-KSPEASRTQ---EIESLASSVGAKDVELTQCREQTETIQEQ---AQSETDRLQKKL 2436
Cdd:TIGR02169  406 RELDRLQEELQRLSEELADLNAAiAGIEAKINEleeEKEDKALEIKKQEWKLEQLAADLSKYEQElydLKEEYDRVEKEL 485

                          330       340
                   ....*....|....*....|....*...
gi 1039770159 2437 TDLQRSLEKFAAalvsqvQMEAAQEYVP 2464
Cdd:TIGR02169  486 SKLQRELAEAEA------QARASEERVR 507
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2947-3282 1.85e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.34  E-value: 1.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2947 TEKSSQelldcSMQQKQSLEMQLEL--SSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELGTTLKAQHKRL----KEL 3020
Cdd:pfam15921  284 TEKASS-----ARSQANSIQSQLEIiqEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLvlanSEL 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3021 EAFRSEVKEKTDEIHFLSDTLAR--EQKNSLELQWALEKEK-ARSGHHEGREKEELEDLKFSLEDqkrRNTQLNLLLEQQ 3097
Cdd:pfam15921  359 TEARTERDQFSQESGNLDDQLQKllADLHKREKELSLEKEQnKRLWDRDTGNSITIDHLRRELDD---RNMEVQRLEALL 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3098 KQLLNESQQKIESqkmlhdaQLSEEQGRNLGLQAlLESEQVRIQEMKSTLDK-ERELYAQLQSREDGGQPPPALPSEdlL 3176
Cdd:pfam15921  436 KAMKSECQGQMER-------QMAAIQGKNESLEK-VSSLTAQLESTKEMLRKvVEELTAKKMTLESSERTVSDLTAS--L 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3177 KELQKQLEEKHSRIVELLSETEkYKLDSLQTRqqmeKDRQVHQKTLQTEQEANtqgQKKMQELQSKVEELQRQLQEKRQQ 3256
Cdd:pfam15921  506 QEKERAIEATNAEITKLRSRVD-LKLQELQHL----KNEGDHLRNVQTECEAL---KLQMAEKDKVIEILRQQIENMTQL 577

                          330       340
                   ....*....|....*....|....*.
gi 1039770159 3257 VYkldlEGKRLQGLMQeFQKQELEPE 3282
Cdd:pfam15921  578 VG----QHGRTAGAMQ-VEKAQLEKE 598
PRK11281 PRK11281
mechanosensitive channel MscK;
501-728 1.91e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.52  E-value: 1.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  501 EKSALQS---QSNDLLEEVRFLREQVQKARQTIAEQENRLSEARKSLstvEDLKAEivAASESRKELElkheaeitnyKI 577
Cdd:PRK11281    57 EDKLVQQdleQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAEL---EALKDD--NDEETRETLS----------TL 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  578 KLEMLEKEKNAVLDRMAESQEA------ELERLRTQLlfshEEELSKLKEDLEvehRIN-IEKLKDNLGIHYKQQIDGLQ 650
Cdd:PRK11281   122 SLRQLESRLAQTLDQLQNAQNDlaeynsQLVSLQTQP----ERAQAALYANSQ---RLQqIRNLLKGGKVGGKALRPSQR 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  651 NEMNRKMESMqcetdNLITQQNQLILE-NSKLRDLqeclVNSKSEEMNLQINELQKEIEILkQE---EKEKGTLEQEVQE 726
Cdd:PRK11281   195 VLLQAEQALL-----NAQNDLQRKSLEgNTQLQDL----LQKQRDYLTARIQRLEHQLQLL-QEainSKRLTLSEKTVQE 264


                   ..
gi 1039770159  727 LQ 728
Cdd:PRK11281   265 AQ 266
PRK11281 PRK11281
mechanosensitive channel MscK;
1967-2301 2.10e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.13  E-value: 2.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1967 EVQCQAEKV--RGDLQKQVKALEIDVEeQVSRFIELEQEKNAELTDLRQQSQALEKQLEKMrkfldeqaidreherdvfQ 2044
Cdd:PRK11281    40 DVQAQLDALnkQKLLEAEDKLVQQDLE-QTLALLDKIDRQKEETEQLKQQLAQAPAKLRQA------------------Q 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2045 QEIQKLEHQLKAVPRiqpvsehqarevEQLTNhlkektdrcsellLSKEQLQRDIQERNEEIEKLecrvreleQALLASA 2124
Cdd:PRK11281   101 AELEALKDDNDEETR------------ETLST-------------LSLRQLESRLAQTLDQLQNA--------QNDLAEY 147

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2125 EpfpkvedqkrsgaveadpelSLEVQLQVerdATDRKQKEITNLEEQLEQFREELENKND---------------EVQEL 2189
Cdd:PRK11281   148 N--------------------SQLVSLQT---QPERAQAALYANSQRLQQIRNLLKGGKVggkalrpsqrvllqaEQALL 204

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2190 LMQLEIQRKE--STTRLQELQQENRlfkviEEQKEQIQDLETQIERLM----SEREHEKKQREEEVEQLTGVVEKLQQEV 2263
Cdd:PRK11281   205 NAQNDLQRKSleGNTQLQDLLQKQR-----DYLTARIQRLEHQLQLLQeainSKRLTLSEKTVQEAQSQDEAARIQANPL 279

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2264 VSTE------------QQREGARTLPEDEESFKHQLDKVTAEKLVLEQQV 2301
Cdd:PRK11281   280 VAQEleinlqlsqrllKATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQI 329
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2923-3086 2.12e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 2.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2923 LLAEIEDLRAQINGGKMTLEREQGTEKSSQELLDCSMQQKQSLEMQLELSSLRDRAAELQEQ---LSSEKMVVAELKSEL 2999
Cdd:COG4913    615 LEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAElerLDASSDDLAALEEQL 694

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3000 AQAKLELGTTLKAQHKRLKELEAFRSEVKEKTDEIHFLSDTL-AREQKNSLELQWALEKEKARSGhHEGREKEELEDLKF 3078
Cdd:COG4913    695 EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLeAAEDLARLELRALLEERFAAAL-GDAVERELRENLEE 773


                   ....*...
gi 1039770159 3079 SLEDQKRR 3086
Cdd:COG4913    774 RIDALRAR 781
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 476-624 2.14e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.60  E-value: 2.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  476 ELNVRLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKARQTIAEQENRLSEARKSLSTV------ED 549
Cdd:COG1579     14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVrnnkeyEA 93

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039770159  550 LKAEIVAASESRKELelkhEAEITNYKIKLEMLEKEKNAVLDRMAEsQEAELERLRTQLlfshEEELSKLKEDLE 624
Cdd:COG1579     94 LQKEIESLKRRISDL----EDEILELMERIEELEEELAELEAELAE-LEAELEEKKAEL----DEELAELEAELE 159
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
127-353 2.20e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 2.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  127 LDDSSSEQGAQSSQTcLQMVEKELAEKQHDIEELTQELEEMRASFG--------TEGLKQLQEFEAAIKQRDGIITQLTA 198
Cdd:COG3206    162 LEQNLELRREEARKA-LEFLEEQLPELRKELEEAEAALEEFRQKNGlvdlseeaKLLLQQLSELESQLAEARAELAEAEA 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  199 NLQQARREKDDTMVEFLELTEQS--QKLQIQFQHLQANETLQNSTLSRTATDLLQAKRQIftqqqqlqdyqkkeEDLQAQ 276
Cdd:COG3206    241 RLAALRAQLGSGPDALPELLQSPviQQLRAQLAELEAELAELSARYTPNHPDVIALRAQI--------------AALRAQ 306

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039770159  277 ISFLQEKLRAfEMEKDRKIENLNAKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLgglhEQLTQRNQEIQ 353
Cdd:COG3206    307 LQQEAQRILA-SLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELY----ESLLQRLEEAR 378
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 593-771 2.39e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.60  E-value: 2.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  593 MAESQEA--ELERLRTQLlFSHEEELSKLKEDLEvEHRINIEKLKDNLgIHYKQQIDGLQNEMNRKmesmqcetdnlitq 670
Cdd:COG1579      2 MPEDLRAllDLQELDSEL-DRLEHRLKELPAELA-ELEDELAALEARL-EAAKTELEDLEKEIKRL-------------- 64

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  671 QNQLILENSKLRDLQECLVNSKSEEmnlQINELQKEIEILKqeeKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCA 750
Cdd:COG1579     65 ELEIEEVEARIKKYEEQLGNVRNNK---EYEALQKEIESLK---RRISDLEDEILELMERIEELEEELAELEAELAELEA 138

                          170       180
                   ....*....|....*....|.
gi 1039770159  751 QLDAENNILKEEKRVLEDKLK 771
Cdd:COG1579    139 ELEEKKAELDEELAELEAELE 159
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 120-607 2.42e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.95  E-value: 2.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  120 LREEEFSLDDSSSEQGAQssqtcLQMVEKELAEKQHDIEELTQE---LEEMRASFGTEGLKQLQEFEAAIKQRDGIITQL 196
Cdd:pfam15921  333 LREAKRMYEDKIEELEKQ-----LVLANSELTEARTERDQFSQEsgnLDDQLQKLLADLHKREKELSLEKEQNKRLWDRD 407

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  197 TAN---LQQARREKDDTMVEF--LELTEQSQKLQIQFQHLQANETLQ--NSTLSRTA--TDLLQAKRQIFTQQQQLQDYQ 267
Cdd:pfam15921  408 TGNsitIDHLRRELDDRNMEVqrLEALLKAMKSECQGQMERQMAAIQgkNESLEKVSslTAQLESTKEMLRKVVEELTAK 487

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  268 K-----KEEDLQAQISFLQEKLRAFE-----MEKDRKIENLNAKEIQE----------KQALIDELNTRVVEEEKKTVEL 327
Cdd:pfam15921  488 KmtlesSERTVSDLTASLQEKERAIEatnaeITKLRSRVDLKLQELQHlknegdhlrnVQTECEALKLQMAEKDKVIEIL 567

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  328 KNKVTTADELLG-------GLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEIKELMRTVEELQkrnlkdswLETSAVRR 400
Cdd:pfam15921  568 RQQIENMTQLVGqhgrtagAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLE--------LEKVKLVN 639

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  401 VEQETQRKLSHLQAELDEMYGKqiVQMKQELINQHMSQIEELKSQHKREMENtlksdtnaaiskeqvnlMNAAINELNVR 480
Cdd:pfam15921  640 AGSERLRAVKDIKQERDQLLNE--VKTSRNELNSLSEDYEVLKRNFRNKSEE-----------------METTTNKLKMQ 700

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  481 LQETHAQKEELKGELGVVLG--------------EKSALQSQSNDLLEEVRFLREQV---QKARQTIAEQENRLSEarkS 543
Cdd:pfam15921  701 LKSAQSELEQTRNTLKSMEGsdghamkvamgmqkQITAKRGQIDALQSKIQFLEEAMtnaNKEKHFLKEEKNKLSQ---E 777

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039770159  544 LSTVEDLKAEIVAASESRKELELKHEAEITNYKIKLEMLEKEKNAVLDrMAESQEAELERLRTQ 607
Cdd:pfam15921  778 LSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQD-IIQRQEQESVRLKLQ 840
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1819-2457 2.43e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.88  E-value: 2.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1819 EAISETNTQLEHAKVTQTELMRESFRQKQEATESLHCLEELRERLQEESRAREQLAEELNKAESVIDGYSDEktlferqi 1898
Cdd:TIGR00606  230 EAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDE-------- 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1899 qEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEAGPVEQQFLQETEKLMKEKLEVQCQAEKVRGD 1978
Cdd:TIGR00606  302 -QLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELD 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1979 LQKQvkalEIDVEEQVSRFIELEQEK--------NAELTDLRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKL 2050
Cdd:TIGR00606  381 GFER----GPFSERQIKNFHTLVIERqedeaktaAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEEL 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2051 EHQLKAVPRIQPVSEHQAREVEQLTNHLKE----------KTDRCSELLLSKEQL-----QRDIQERNEEIEKLECRVRE 2115
Cdd:TIGR00606  457 KFVIKELQQLEGSSDRILELDQELRKAERElskaeknsltETLKKEVKSLQNEKAdldrkLRKLDQEMEQLNHHTTTRTQ 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2116 LEQALLASAEPFPKVEDQKRSGAVEADPELSLEVQLQVERDATDRKQKEITNLEEQLEQFREELENKNDevqellMQLEI 2195
Cdd:TIGR00606  537 MEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQ------NKNHI 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2196 QRKESTTRLQELQQENRLFKVIEEqkeqiQDLETQIERLMSEREHEKKQR----------EEEVEQLTG----------- 2254
Cdd:TIGR00606  611 NNELESKEEQLSSYEDKLFDVCGS-----QDEESDLERLKEEIEKSSKQRamlagatavySQFITQLTDenqsccpvcqr 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2255 --VVEKLQQEVVSTEQQRegARTLPEDEESFKHQLDKVTAEKLVLEQQVETTNQVMTHMNNVLKEINFKMDQITQSLCNL 2332
Cdd:TIGR00606  686 vfQTEAELQEFISDLQSK--LRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRL 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2333 NKECASNE-ELPSLPKESVHMTVHELGSDNLQPEDAPAQDVTKPLEKQTSltRLQKSPEASRTQEIESLASSVGAKDVEL 2411
Cdd:TIGR00606  764 KNDIEEQEtLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAA--KLQGSDLDRTVQQVNQEKQEKQHELDTV 841

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*.
gi 1039770159 2412 TQCREQTETIQEQAQSETDRLQKKLTDLQRSLEKFAAALVSQVQME 2457
Cdd:TIGR00606  842 VSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFE 887
PRK05431 PRK05431
seryl-tRNA synthetase; Provisional
 680-747 2.44e-03

seryl-tRNA synthetase; Provisional


Pssm-ID: 235461 [Multi-domain]  Cd Length: 425  Bit Score: 43.52  E-value: 2.44e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039770159  680 KLRDLQeclvnSKSEEMNLQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQE 747
Cdd:PRK05431    36 ERRELQ-----TELEELQAERNALSKEIGQAKRKGEDAEALIAEVKELKEEIKALEAELDELEAELEE 98
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 146-813 2.53e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.88  E-value: 2.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  146 VEKELAEKQHDIEELTQELEEMRASFGTEGLkQLQEFEAAIKQRDGIITQLTANLQQARREKDD----TMVEFLELTEQS 221
Cdd:TIGR00606  324 CQRELEKLNKERRLLNQEKTELLVEQGRLQL-QADRHQEHIRARDSLIQSLATRLELDGFERGPfserQIKNFHTLVIER 402

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  222 QKLQIQFQHLQANETLQNSTLSRTATDLLQAKRQIF--TQQQQLQDYQKKEEDLQAQISFLQ-------------EKLRA 286
Cdd:TIGR00606  403 QEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLgrTIELKKEILEKKQEELKFVIKELQqlegssdrileldQELRK 482

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  287 FE-----MEKDRKIENLNAKEIQEKQALIDELNTRVVEEEK------------KTVELKNKVTTADEllgGLHEQLTQRN 349
Cdd:TIGR00606  483 AErelskAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEmeqlnhhtttrtQMEMLTKDKMDKDE---QIRKIKSRHS 559

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  350 QEIQSLKLELGNSQQNERKCSEEIKELMRTVEELQKRNLKDSWLETSA--VRRVEQETQRKLSHLQAELDEMYGKQIVQM 427
Cdd:TIGR00606  560 DELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKnhINNELESKEEQLSSYEDKLFDVCGSQDEES 639

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  428 KQELINQHMSQIEELKSQ-------HKREMENTLKSDTNAAISKEQVNLMNAAINELNVRLQ-----------ETHAQKE 489
Cdd:TIGR00606  640 DLERLKEEIEKSSKQRAMlagatavYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQsklrlapdklkSTESELK 719

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  490 ELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKARQTIAEQENRLSEARKSLSTVEdlkaeivaASESRKELELKHE 569
Cdd:TIGR00606  720 KKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIM--------PEEESAKVCLTDV 791

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  570 AEITNYKIKLEMLEKEknaVLDRMAESQEAELERLRTQllfsheeeLSKLKEDLEVEHRINIEKLKDN--LGIHYKQQID 647
Cdd:TIGR00606  792 TIMERFQMELKDVERK---IAQQAAKLQGSDLDRTVQQ--------VNQEKQEKQHELDTVVSKIELNrkLIQDQQEQIQ 860

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  648 GLQNEMNR-KMESMQCETDNLITQQ--NQLILENSKLRDLQECLVNSKSEEMNLQI---NELQKEIEILKQEEKEKGTLE 721
Cdd:TIGR00606  861 HLKSKTNElKSEKLQIGTNLQRRQQfeEQLVELSTEVQSLIREIKDAKEQDSPLETfleKDQQEKEELISSKETSNKKAQ 940

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  722 QEVQELQLKTEQLEKQLKEKEDDLQEKCAQ--LDAENNILKEEKRvLEDKLKMYSPSEQEERSIAVDPSTSKSADsRWQK 799
Cdd:TIGR00606  941 DKVNDIKEKVKNIHGYMKDIENKIQDGKDDylKQKETELNTVNAQ-LEECEKHQEKINEDMRLMRQDIDTQKIQE-RWLQ 1018

                          730
                   ....*....|....
gi 1039770159  800 EVAMLRKETEDLQQ 813
Cdd:TIGR00606 1019 DNLTLRKRENELKE 1032
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 575-962 3.06e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 43.88  E-value: 3.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  575 YKIKLEMLEKEKNAVLDRMaesqEAELERLRTQLLFSH---EEEL---SKLKEDLevehrinIEKLKDNLGIHYKQQIDG 648
Cdd:PTZ00108   986 YLVRLDLYKKRKEYLLGKL----ERELARLSNKVRFIKhviNGELvitNAKKKDL-------VKELKKLGYVRFKDIIKK 1054

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  649 lqNEMNRKMESMQCETDNLITQQNQLILENSKLRDLQECL-------VNSKSEEMNLQINELQKEIEILKQEEKEKGTLE 721
Cdd:PTZ00108  1055 --KSEKITAEEEEGAEEDDEADDEDDEEELGAAVSYDYLLsmpiwslTKEKVEKLNAELEKKEKELEKLKNTTPKDMWLE 1132

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  722 qevqELQLKTEQLEKQLKEKEDDLQE----KCAQLDAENNILKEEKRVLEDKLKMYSPSEQEERSIAVDPSTSKSADSRW 797
Cdd:PTZ00108  1133 ----DLDKFEEALEEQEEVEEKEIAKeqrlKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRK 1208

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  798 QKEVAMLRKETEDLQQQclYLNEEIEKQRNTFAFAEKNFEVNYQELQREYTCLLKIRDDLEATQTKQALEYESKLRAlee 877
Cdd:PTZ00108  1209 LDDKPDNKKSNSSGSDQ--EDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQY--- 1283

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  878 elLSKRGNPAAPKGKSSGIFPSETleIGEVVEKDTTELMEKLEVTKREKLELSEKVSgLSEQLKQthCTINSLSAEVRAL 957
Cdd:PTZ00108  1284 --SPPPPSKRPDGESNGGSKPSSP--TKKKVKKRLEGSLAALKKKKKSEKKTARKKK-SKTRVKQ--ASASQSSRLLRRP 1356


                   ....*
gi 1039770159  958 KQEKE 962
Cdd:PTZ00108  1357 RKKKS 1361
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1867-2096 3.11e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.47  E-value: 3.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1867 SRAREQLAEELNKAESVIDgySDEKTLfeRQIQEKTDIIEhLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAE 1946
Cdd:COG3206    174 RKALEFLEEQLPELRKELE--EAEAAL--EEFRQKNGLVD-LSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQ 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1947 AGPVEQQflqeteklmkeklEVQCQAEKVRGDLQKQVKALEIDVEEQVSRFieleQEKNAELTDLRQQSQALEKQLEK-M 2025
Cdd:COG3206    249 LGSGPDA-------------LPELLQSPVIQQLRAQLAELEAELAELSARY----TPNHPDVIALRAQIAALRAQLQQeA 311

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039770159 2026 RKFLDEQAIDRE---HERDVFQQEIQKLEHQLKAVPRIQpvsehqaREVEQLTNHLKEKTDRCSELLLSKEQLQ 2096
Cdd:COG3206    312 QRILASLEAELEalqAREASLQAQLAQLEARLAELPELE-------AELRRLEREVEVARELYESLLQRLEEAR 378
PRK05431 PRK05431
seryl-tRNA synthetase; Provisional
 2168-2252 3.44e-03

seryl-tRNA synthetase; Provisional


Pssm-ID: 235461 [Multi-domain]  Cd Length: 425  Bit Score: 43.13  E-value: 3.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2168 LEEQLEQFREELENKNDE--VQELLmQLEIQRKESTTRLQELQQE-NRLFKVI----------EEQKEQIQDLETQIERL 2234
Cdd:PRK05431     7 IRENPEAVKEALAKRGFPldVDELL-ELDEERRELQTELEELQAErNALSKEIgqakrkgedaEALIAEVKELKEEIKAL 85

                           90
                   ....*....|....*...
gi 1039770159 2235 mserEHEKKQREEEVEQL 2252
Cdd:PRK05431    86 ----EAELDELEAELEEL 99
SerS COG0172
Seryl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Seryl-tRNA synthetase ...
 2168-2252 3.86e-03

Seryl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Seryl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439942 [Multi-domain]  Cd Length: 421  Bit Score: 42.68  E-value: 3.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2168 LEEQLEQFREELENKNDE--VQELLmQLEIQRKESTTRLQELQQE-NRLFKVI----------EEQKEQIQDLETQIERL 2234
Cdd:COG0172      7 IRENPEAVKEALAKRGFDldVDELL-ELDEERRELQTEVEELRAErNALSKEIgkakkkgeeaEALIAEVKELKEEIKEL 85

                           90
                   ....*....|....*...
gi 1039770159 2235 mserEHEKKQREEEVEQL 2252
Cdd:COG0172     86 ----EEELKELEEELDEL 99
PRK11281 PRK11281
mechanosensitive channel MscK;
538-820 3.94e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 43.36  E-value: 3.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  538 SEARKSLSTVEDLKAEIVAASEsRKELELKHEAEITNYKIKLEMLEKeknavldrmAESQEAELERLRTQLlfshEEELS 617
Cdd:PRK11281    29 AASNGDLPTEADVQAQLDALNK-QKLLEAEDKLVQQDLEQTLALLDK---------IDRQKEETEQLKQQL----AQAPA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  618 KLKEDLEvehriNIEKLKDNLGIHYKQQIDGLQNemnRKMESMQCET-DNLITQQNQLILENSKLRDLQ--------ECL 688
Cdd:PRK11281    95 KLRQAQA-----ELEALKDDNDEETRETLSTLSL---RQLESRLAQTlDQLQNAQNDLAEYNSQLVSLQtqperaqaALY 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  689 VNSK-SEEMNLQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQ--------LKEKEDDLQEKCAQLDAENNIL 759
Cdd:PRK11281   167 ANSQrLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQRKSLEgntqlqdlLQKQRDYLTARIQRLEHQLQLL 246

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039770159  760 KE---EKRVLEdklkmyspSEQE-ERSIAVDPSTSKSADSRWQKEVAMLRKETEDLQQQCLYLNE 820
Cdd:PRK11281   247 QEainSKRLTL--------SEKTvQEAQSQDEAARIQANPLVAQELEINLQLSQRLLKATEKLNT 303
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2960-3189 4.07e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 4.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2960 QQKQSLEMQLELSSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELGTTLKAQHKRLKELEAFRSEVKEKTDEIHFLSD 3039
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3040 TLAREQKNSLELQWALEKEKARSGHHEGREKEELEDLKFSLEDQKRRNTQLNLLLEQQKQLLNE---SQQKIESQKMLHD 3116
Cdd:COG4942     98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAElaaLRAELEAERAELE 177

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039770159 3117 AQLSEEQGRNLGLQALLESEQVRIQEMKSTLDKERELYAQLQSREDGgqpppalpSEDLLKELQKQLEEKHSR 3189
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE--------LEALIARLEAEAAAAAER 242
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
2168-2296 4.08e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 42.92  E-value: 4.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2168 LEEQLEQFREELENKNDEVQELLMQL-EIQRKESTTRLQELQQE-NRLFKVIEEQKEQIQDLETQIERL------MSERE 2239
Cdd:COG2433    378 IEEALEELIEKELPEEEPEAEREKEHeERELTEEEEEIRRLEEQvERLEAEVEELEAELEEKDERIERLerelseARSEE 457

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1039770159 2240 HEKKQREEEVEQLTGVVEKLQQEVvstEQQREGARTLPEDEESFKHQLDKVTAEKLV 2296
Cdd:COG2433    458 RREIRKDREISRLDREIERLEREL---EEERERIEELKRKLERLKELWKLEHSGELV 511
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
3102-3275 4.19e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.08  E-value: 4.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3102 NESQQKIESQKMLHDAQLSEEQGrNLGLQALLESEQvRIQEMKSTLDKERELYAQLQSR-EDGGQPPPALPSEDLLKELQ 3180
Cdd:COG3206    192 EEAEAALEEFRQKNGLVDLSEEA-KLLLQQLSELES-QLAEARAELAEAEARLAALRAQlGSGPDALPELLQSPVIQQLR 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3181 KQLEEKHSRIVELLSeteKYKLDSLQTRQQMEKDRQVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQQVYKL 3260
Cdd:COG3206    270 AQLAELEAELAELSA---RYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAEL 346

                          170
                   ....*....|....*
gi 1039770159 3261 DLEGKRLQGLMQEFQ 3275
Cdd:COG3206    347 PELEAELRRLEREVE 361
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 3070-3256 4.21e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 4.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3070 KEELEDLKFSLEDQKRRNTQLNLLLEQQKQLLNESQQKIESQKmlhdAQLSEEQGRNLGLQALLESEQVRIQEMKSTLDK 3149
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA----RRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3150 ERELYAQL--QSREDGGQPPPA--LPSEDL-----------------------LKELQKQLEEKHSRIVELLSETEKYKL 3202
Cdd:COG4942    102 QKEELAELlrALYRLGRQPPLAllLSPEDFldavrrlqylkylaparreqaeeLRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1039770159 3203 DSLQTRQQMEKDRQVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQQ 3256
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1523-1708 4.33e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.19  E-value: 4.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1523 VRKSMHDEVLVSSMDTSRQLILNEQLEDMRQELVRQYEEHQQATEMLRQAHMQQMERQREDQEQLQEEIKRLNEQLA--- 1599
Cdd:pfam17380  394 VRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEerk 473

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1600 ------QKSSIDTEHVVSERERVLLEELEALKQLPLA---GRKELCCELRHSSTQTQDGHDDQEVEEQTLKDKTLERSPE 1670
Cdd:pfam17380  474 rkklelEKEKRDRKRAEEQRRKILEKELEERKQAMIEeerKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRR 553

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1039770159 1671 DALLDRNLSNERYALkKANNRLLKILLEVVKTTSAAEE 1708
Cdd:pfam17380  554 IQEQMRKATEERSRL-EAMEREREMMRQIVESEKARAE 590
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2156-2335 4.55e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 4.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2156 DATDRKQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRK---ESTTRLQELQQEnrlfkvIEEQKEQIQDLETQIE 2232
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERriaALARRIRALEQE------LAALEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2233 RLmserEHEKKQREEEVEQLTGVVEKLQQE-----VVSTEQQREGARTL-------PEDE---ESFKHQLDKVTAEKLVL 2297
Cdd:COG4942     94 EL----RAELEAQKEELAELLRALYRLGRQpplalLLSPEDFLDAVRRLqylkylaPARReqaEELRADLAELAALRAEL 169

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1039770159 2298 EQQVETTNQVMTHMNNVLKEINFKMDQITQSLCNLNKE 2335
Cdd:COG4942    170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKE 207
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 2089-2306 4.56e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.80  E-value: 4.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2089 LLSKEQLQRDIQERN--EEIEKLEC-RVRELEQALLASAEPFPKVEDQKRSGAVEADPELSleVQLQVERDATDRkqkei 2165
Cdd:pfam17380  274 LLHIVQHQKAVSERQqqEKFEKMEQeRLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAA--IYAEQERMAMER----- 346

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2166 tnlEEQLEQFR-EELENKNDEVQELLMQLEIQRKESTTRLQ-ELQQENRLFKvieeqkeqiQDLETQIERLMSEREHEKK 2243
Cdd:pfam17380  347 ---ERELERIRqEERKRELERIRQEEIAMEISRMRELERLQmERQQKNERVR---------QELEAARKVKILEEERQRK 414

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039770159 2244 QREEEVEQltgvveklqqEVVSTEQQREGARTLPEDEESFKHQLDKVTAEKLVLEQQVETTNQ 2306
Cdd:pfam17380  415 IQQQKVEM----------EQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQ 467
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 656-762 4.77e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 42.76  E-value: 4.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  656 KMESMQCETDNLITQQNQLILENSKLRDLQECLVNSKSEEMNLQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLE 735
Cdd:COG0542    405 EIDSKPEELDELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARWEAEKELIEEIQELKEELEQRY 484

                           90       100
                   ....*....|....*....|....*..
gi 1039770159  736 KQLKEKEDDLQEKCAQLDAENNILKEE 762
Cdd:COG0542    485 GKIPELEKELAELEEELAELAPLLREE 511
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
403-631 5.30e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 5.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  403 QETQRKLSHLQAELDEMyGKQIVQMKQEL--INQHMSQIEELKSQHKReMENTLKSDTNAA-----IS-----KEQVNLM 470
Cdd:COG4913    606 FDNRAKLAALEAELAEL-EEELAEAEERLeaLEAELDALQERREALQR-LAEYSWDEIDVAsaereIAeleaeLERLDAS 683

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  471 NAAINELNVRLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKARQTIAEQ-----ENRLSEARKSLS 545
Cdd:COG4913    684 SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLElrallEERFAAALGDAV 763

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  546 T---VEDLKAEIVAASESRKELELKHEAEITNYKIKLEMLEKEKNAVLDRMAESQeAELERLRTQLLFSHEEELSKLKED 622
Cdd:COG4913    764 ErelRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYL-ALLDRLEEDGLPEYEERFKELLNE 842


                   ....*....
gi 1039770159  623 LEVEHRINI 631
Cdd:COG4913    843 NSIEFVADL 851
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
370-577 5.31e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 5.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  370 SEEIKELMRTVEELQKR--NLKDSWLETSAVRRVEQETQRkLSHLQAELDEmygkqiVQMKQELINQHMSQIEELKSQHK 447
Cdd:COG3206    181 EEQLPELRKELEEAEAAleEFRQKNGLVDLSEEAKLLLQQ-LSELESQLAE------ARAELAEAEARLAALRAQLGSGP 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  448 REMENTLKSDTNAAIsKEQVNLMNAAINELNVRLQETHAQKEELKGELGVVLGE-KSALQSQSNDLLEEVRFLREQVQKA 526
Cdd:COG3206    254 DALPELLQSPVIQQL-RAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQlQQEAQRILASLEAELEALQAREASL 332

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039770159  527 RQTIAEQENRLSEARKSLSTVEDLKAEIVAASE-------SRKELELKHEAEITNYKI 577
Cdd:COG3206    333 QAQLAQLEARLAELPELEAELRRLEREVEVARElyesllqRLEEARLAEALTVGNVRV 390
PRK12705 PRK12705
hypothetical protein; Provisional
 2088-2239 5.37e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 42.39  E-value: 5.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2088 LLLSKEQLQRDIQERNEEIEKLECRvRELEQALLASAEPFPKVEDQKRSGAVEADPELSLEVQLQVER-DATDRKQKEIT 2166
Cdd:PRK12705    23 VLLKKRQRLAKEAERILQEAQKEAE-EKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKeEQLDARAEKLD 101

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770159 2167 NLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQE---NRLFKVIEEQKEQIQDLETQIERLMSERE 2239
Cdd:PRK12705   102 NLENQLEEREKALSARELELEELEKQLDNELYRVAGLTPEQARKlllKLLDAELEEEKAQRVKKIEEEADLEAERK 177
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2119-2302 5.52e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 5.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2119 ALLASAEPFPKVEDQKRSGAVEADPEL-----SLEVQLQVERDATDRKQKEITNLEEQLEQFREELENKNDEVQELLMQL 2193
Cdd:COG3883      9 PTPAFADPQIQAKQKELSELQAELEAAqaeldALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREEL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2194 E-----IQRKESTTRLQE-----------LQQENRLFKVIEEQKEQIQDLETQIERLmserEHEKKQREEEVEQLTGVVE 2257
Cdd:COG3883     89 GeraraLYRSGGSVSYLDvllgsesfsdfLDRLSALSKIADADADLLEELKADKAEL----EAKKAELEAKLAELEALKA 164

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1039770159 2258 KLQQEVVSTEQQREGARTLPEDEESfkhQLDKVTAEKLVLEQQVE 2302
Cdd:COG3883    165 ELEAAKAELEAQQAEQEALLAQLSA---EEAAAEAQLAELEAELA 206
PRK01156 PRK01156
chromosome segregation protein; Provisional
 450-786 5.76e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 42.58  E-value: 5.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  450 MENTLKSdtnaaiSKEQVNLMNAAINELNVRLQETHAQKEELKGELGVVLGEKSALQSQSNDL---LEEVRFLREQVQKA 526
Cdd:PRK01156   188 LEEKLKS------SNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELsslEDMKNRYESEIKTA 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  527 RQTIAEQENRLSEARKSLSTVEDLKAEIVAASESRKELELKHEAEITNYKIKLEMLEKEKNAVLDRMAESQEAELERLRT 606
Cdd:PRK01156   262 ESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAIIKKLSVLQKDYNDY 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  607 QLLFSHEEELSKLKEDLEVEHR------INIEKLKDNLGiHYKQQIDGLQNEMNRKMESMQCETDNLITQQNQLileNSK 680
Cdd:PRK01156   342 IKKKSRYDDLNNQILELEGYEMdynsylKSIESLKKKIE-EYSKNIERMSAFISEILKIQEIDPDAIKKELNEI---NVK 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  681 LRDlqeclVNSKSEEMNLQINEL-QKEIEILKQEEKEKGTLEQEVQELQL---KTEQLEKQLKEKEDDLQEKCAQLDAEN 756
Cdd:PRK01156   418 LQD-----ISSKVSSLNQRIRALrENLDELSRNMEMLNGQSVCPVCGTTLgeeKSNHIINHYNEKKSRLEEKIREIEIEV 492

                          330       340       350
                   ....*....|....*....|....*....|
gi 1039770159  757 NILKEEKRVLEdKLKMYSPSEQEERSIAVD 786
Cdd:PRK01156   493 KDIDEKIVDLK-KRKEYLESEEINKSINEY 521
PTZ00121 PTZ00121
MAEBL; Provisional
 3022-3255 6.13e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 6.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3022 AFRSEVKEKTDEIHflsdtLAREQKNSLELQWALEKEKARSGHHEGREKEELEDLKFSLEDQKRRntqlnllleqqkqlL 3101
Cdd:PTZ00121  1271 AIKAEEARKADELK-----KAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKK--------------A 1331

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3102 NESQQKIESQKMLHDAQLSEEQGRNLGLQAllESEQVRIQEMKSTLDKERELYAQLQSREdggqpppalpsEDLLKELQK 3181
Cdd:PTZ00121  1332 DAAKKKAEEAKKAAEAAKAEAEAAADEAEA--AEEKAEAAEKKKEEAKKKADAAKKKAEE-----------KKKADEAKK 1398

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039770159 3182 QLEEKHSRIVELL-SETEKYKLDSLqtRQQMEKDRQVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQ 3255
Cdd:PTZ00121  1399 KAEEDKKKADELKkAAAAKKKADEA--KKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKK 1471
PRK12704 PRK12704
phosphodiesterase; Provisional
 1955-2107 7.00e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 7.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1955 LQETEKLMKEKLEVQCQAEKVRGDLQKQVKALeIDVEEQVSRFIELEQEKNAELTDLRQQSQALEKQLEKMRKFLDEQAi 2034
Cdd:PRK12704    60 LEAKEEIHKLRNEFEKELRERRNELQKLEKRL-LQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELI- 137

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039770159 2035 dreherdvfQQEIQKLEhqlkavpRIQPVSEHQARevEQLTNHLKEKtdrcselllSKEQLQRDIQERNEEIE 2107
Cdd:PRK12704   138 ---------EEQLQELE-------RISGLTAEEAK--EILLEKVEEE---------ARHEAAVLIKEIEEEAK 183
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 2159-2265 7.91e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 42.38  E-value: 7.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2159 DRKQKEITNLEEQLEQFREELE----NKNDEVQELLMQLEIQRKESTTRLQEL----QQENRLFKVIEEQKEQIQDLETQ 2230
Cdd:COG0542    407 DSKPEELDELERRLEQLEIEKEalkkEQDEASFERLAELRDELAELEEELEALkarwEAEKELIEEIQELKEELEQRYGK 486

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 1039770159 2231 IERLMSEREHEKKQREEEVEQLTGVV-EKLQQEVVS 2265
Cdd:COG0542    487 IPELEKELAELEEELAELAPLLREEVtEEDIAEVVS 522
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 432-607 8.06e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.06  E-value: 8.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  432 INQHMSQIEELKSQHKREMENTLKSDTNAAISKEQVNLMNAAINELNVRLQETHAQKEELKGELGVVLGEKsalqsQSND 511
Cdd:COG1579     19 LDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNK-----EYEA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  512 LLEEVRFLREQVQKARQTIAEQENRLSEARKslsTVEDLKAEIVAASESRKELELKHEAEITNYKIKLEMLEKEKNAVLD 591
Cdd:COG1579     94 LQKEIESLKRRISDLEDEILELMERIEELEE---ELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAA 170

                          170
                   ....*....|....*.
gi 1039770159  592 RMAESQEAELERLRTQ 607
Cdd:COG1579    171 KIPPELLALYERIRKR 186
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
143-572 8.70e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 8.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  143 LQMVEKELAEKQhdIEELTQELEEMRASfGTEGLKQLQEFEAAIKQRDGIITQLTANLQQARREKDDTMVEFLELTEQSQ 222
Cdd:PRK03918   374 LERLKKRLTGLT--PEKLEKELEELEKA-KEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHR 450

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  223 KlqiqfqHLQANETLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLqEKLRAFEmekdRKIENLNAKE 302
Cdd:PRK03918   451 K------ELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELA-EQLKELE----EKLKKYNLEE 519

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  303 IQEKQALIDELNTRVVEEEKKTVELKNKVttadELLGGLHEQLTQRNQEIQSLKLELGN-SQQNERKCSEEIKELMRTVE 381
Cdd:PRK03918   520 LEKKAEEYEKLKEKLIKLKGEIKSLKKEL----EKLEELKKKLAELEKKLDELEEELAElLKELEELGFESVEELEERLK 595

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  382 ELQKrnLKDSWLETSAVRRVEQETQRKLSHLQAELDEmygkqivqmKQELINQHMSQIEELKSQhkrementlksdtnaa 461
Cdd:PRK03918   596 ELEP--FYNEYLELKDAEKELEREEKELKKLEEELDK---------AFEELAETEKRLEELRKE---------------- 648

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  462 iskeqvnlmnaaINELNVRL-QETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKARQTIAEQENRLSEA 540
Cdd:PRK03918   649 ------------LEELEKKYsEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKL 716

                          410       420       430
                   ....*....|....*....|....*....|..
gi 1039770159  541 RKSLSTVEDLKAEIVAASESRKELELKHEAEI 572
Cdd:PRK03918   717 EKALERVEELREKVKKYKALLKERALSKVGEI 748
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2092-2273 8.86e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 8.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2092 KEQLQRDIQERNEEIEKLECRVRELEQALLASAEpfpKVEDqkrsgaveadpelsLEVQLQVERDATDRKQKEITNLEEQ 2171
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNE---EYNE--------------LQAELEALQAEIDKLQAEIAEAEAE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2172 LEQFREELEN-------------------KNDEVQELLMQLEIQRKESTTRLQELQQENRLFKVIEEQKEQIQDLETQIE 2232
Cdd:COG3883     81 IEERREELGEraralyrsggsvsyldvllGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELE 160

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1039770159 2233 RLMSEREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQREGA 2273
Cdd:COG3883    161 ALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAEL 201
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 2164-2262 8.93e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.12  E-value: 8.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2164 EITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENRlfKVIEEQKEQIQDLetqIERLMSEREHEKK 2243
Cdd:PRK00409   517 KLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEED--KLLEEAEKEAQQA---IKEAKKEADEIIK 591

                           90       100
                   ....*....|....*....|
gi 1039770159 2244 Q-REEEVEQLTGVVEKLQQE 2262
Cdd:PRK00409   592 ElRQLQKGGYASVKAHELIE 611
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1959-2294 8.96e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.25  E-value: 8.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 1959 EKLMKEKLEVQCQAEKVRGDLQKQVKAleidvEEQVSRFI------ELEQEKNAELTDLRQQSQALEKQLEKMRKFLDEQ 2032
Cdd:COG3096    788 EELRAERDELAEQYAKASFDVQKLQRL-----HQAFSQFVgghlavAFAPDPEAELAALRQRRSELERELAQHRAQEQQL 862

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2033 aidreherdvfQQEIQKLEHQLKAVPRIQPVSEHQAREveqltnHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECR 2112
Cdd:COG3096    863 -----------RQQLDQLKEQLQLLNKLLPQANLLADE------TLADRLEELREELDAAQEAQAFIQQHGKALAQLEPL 925

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2113 VRELEQallasaepfpkveDQKRSGAVEADPElslevQLQVERDATDRKQKEITNLEEQLEQF----REELENK----ND 2184
Cdd:COG3096    926 VAVLQS-------------DPEQFEQLQADYL-----QAKEQQRRLKQQIFALSEVVQRRPHFsyedAVGLLGEnsdlNE 987

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2185 EVQELLMQLEIQRKESTTRLQELQQE----NRLF-----------KVIEEQKEQIQDLETQIERLMSEREHEKKQR-EEE 2248
Cdd:COG3096    988 KLRARLEQAEEARREAREQLRQAQAQysqyNQVLaslkssrdakqQTLQELEQELEELGVQADAEAEERARIRRDElHEE 1067

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 1039770159 2249 VEQLTGVVEKLQQEVVSTE-QQREGARTLPEDEESFKHQLDKVTAEK 2294
Cdd:COG3096   1068 LSQNRSRRSQLEKQLTRCEaEMDSLQKRLRKAERDYKQEREQVVQAK 1114
46 PHA02562
endonuclease subunit; Provisional
 2099-2337 9.01e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 9.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2099 IQERNEEIEKLECRVRELEQallasaepfpKVEDQKRSgaveadpelsLEVQLQVERDATDRKQKEITNLEEQLEQFREE 2178
Cdd:PHA02562   176 IRELNQQIQTLDMKIDHIQQ----------QIKTYNKN----------IEEQRKKNGENIARKQNKYDELVEEAKTIKAE 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2179 LENKNDEVQELLMQLEiqrkESTTRLQELQQEnrLFKvIEEQKEQIQDLETqierlMSEREHEKKQREEEVEQLTGVVEK 2258
Cdd:PHA02562   236 IEELTDELLNLVMDIE----DPSAALNKLNTA--AAK-IKSKIEQFQKVIK-----MYEKGGVCPTCTQQISEGPDRITK 303

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039770159 2259 LQQEVVSTEQQREGARTLPEDEESFKHQLDKVTAEKLVLEQQVETTNQVMTHMNNVLKEINFKMDQITQSLCNLNKECA 2337
Cdd:PHA02562   304 IKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELA 382
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 380-762 9.75e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 41.76  E-value: 9.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  380 VEELQKRNLKDSWLETSAVRRVEQETqrklshlqaeldEMYGKQIVQMKQ------ELINQHMsqIEELKSQHKREMent 453
Cdd:PLN03229   413 VDPERKVNMKKREAVKTPVRELEGEV------------EKLKEQILKAKEssskpsELALNEM--IEKLKKEIDLEY--- 475

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  454 lksdTNAAIS---KEQVNLMNAAINELNVRLQETHA----QKEELKGELGVVLGEKSALQSqsndLLEEVRFLREqvqka 526
Cdd:PLN03229   476 ----TEAVIAmglQERLENLREEFSKANSQDQLMHPvlmeKIEKLKDEFNKRLSRAPNYLS----LKYKLDMLNE----- 542

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  527 rqtiAEQENRLSEARkslSTVEDLKAEI---VAASESRKELELKHEAeitnYKIKLEMLEKEKNAVLDrmaESQEAELER 603
Cdd:PLN03229   543 ----FSRAKALSEKK---SKAEKLKAEInkkFKEVMDRPEIKEKMEA----LKAEVASSGASSGDELD---DDLKEKVEK 608

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  604 LRTQLLFSHEEELSKLKEDLEVEHRINIEKLKDNLGIHYKQQIDGLQNEMNRKMESMQCETDnLITQQNQLILENSKlrd 683
Cdd:PLN03229   609 MKKEIELELAGVLKSMGLEVIGVTKKNKDTAEQTPPPNLQEKIESLNEEINKKIERVIRSSD-LKSKIELLKLEVAK--- 684

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039770159  684 lqeclvNSKSEEMnlqinELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLdaENNILKEE 762
Cdd:PLN03229   685 ------ASKTPDV-----TEKEKIEALEQQIKQKIAEALNSSELKEKFEELEAELAAARETAAESNGSL--KNDDDKEE 750
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 533-942 9.75e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 41.76  E-value: 9.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  533 QENRLSEARKSLSTVEDLKAEIVAASESRKELElkheAEITNykiklEMLEKEKNAVLDRMAESQEAELERLRTQLLfsh 612
Cdd:PLN03229   424 REAVKTPVRELEGEVEKLKEQILKAKESSSKPS----ELALN-----EMIEKLKKEIDLEYTEAVIAMGLQERLENL--- 491

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  613 EEELSKLKEDLEVEHRINIEKlkdnlgihykqqIDGLQNEMNRKMESMQCETDnlITQQNQLILENSKLRDLQEclVNSK 692
Cdd:PLN03229   492 REEFSKANSQDQLMHPVLMEK------------IEKLKDEFNKRLSRAPNYLS--LKYKLDMLNEFSRAKALSE--KKSK 555

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  693 SEEMNLQINELQKEIeILKQEEKEK-GTLEQEVQELQLKTE-QLEKQLKEKeddlqekcaQLDAENNILKEEKRVLEDKl 770
Cdd:PLN03229   556 AEKLKAEINKKFKEV-MDRPEIKEKmEALKAEVASSGASSGdELDDDLKEK---------VEKMKKEIELELAGVLKSM- 624

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  771 kmyspseqeerSIAVDPSTSKSADSRWQKEVAMLRKETEDLQQQclyLNEEIEKQRNTFAFAEKnfevnYQELQREYTcl 850
Cdd:PLN03229   625 -----------GLEVIGVTKKNKDTAEQTPPPNLQEKIESLNEE---INKKIERVIRSSDLKSK-----IELLKLEVA-- 683

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159  851 lkirddlEATQTKQALEYEsKLRALEEELLSKrgnpaapkgkssgifpsetleIGEVVekDTTELMEKLEVTKREKLELS 930
Cdd:PLN03229   684 -------KASKTPDVTEKE-KIEALEQQIKQK---------------------IAEAL--NSSELKEKFEELEAELAAAR 732

                          410
                   ....*....|..
gi 1039770159  931 EKVSGLSEQLKQ 942
Cdd:PLN03229   733 ETAAESNGSLKN 744
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 3166-3260 9.82e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 9.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 3166 PPPALPSEDLLKELQKQLEEKHSRIVEL---LSETEKYKLDSLQTRQQMEKDRQVHQKTLQTEQEANTQGQKKMQELQSK 3242
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELekeLAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE 91

                           90
                   ....*....|....*...
gi 1039770159 3243 VEELQRQLQEKRQQVYKL 3260
Cdd:COG4942     92 IAELRAELEAQKEELAEL 109
Taxilin pfam09728
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ...
 2084-2261 9.92e-03

Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.


Pssm-ID: 462861 [Multi-domain]  Cd Length: 302  Bit Score: 41.09  E-value: 9.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2084 RCSELLLSKEQLQRDIQERNEEIEKLECRVRELE---QALLASAEPFPKVEDQKRSGAVEADPELSLEVQLQVERDATDR 2160
Cdd:pfam09728   47 KQDQLQKEKDQLQSELSKAILAKSKLEKLCRELQkqnKKLKEESKKLAKEEEEKRKELSEKFQSTLKDIQDKMEEKSEKN 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770159 2161 KQ--KEITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENRLFKvIEEQKEQIQDLETQIERLMSEr 2238
Cdd:pfam09728  127 NKlrEENEELREKLKSLIEQYELRELHFEKLLKTKELEVQLAEAKLQQATEEEEKKA-QEKEVAKARELKAQVQTLSET- 204

                          170       180
                   ....*....|....*....|...
gi 1039770159 2239 ehEKKQReeevEQLTGVVEKLQQ 2261
Cdd:pfam09728  205 --EKELR----EQLNLYVEKFEE 221
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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