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Conserved domains on  [gi|1039783175|ref|XP_017168057|]
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peptidyl-prolyl cis-trans isomerase FKBP8 isoform X2 [Mus musculus]

Protein Classification

FKBP_C and TPR domain-containing protein( domain architecture ID 11991378)

FKBP_C and TPR domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FKBP_C pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase;
103-191 5.96e-20

FKBP-type peptidyl-prolyl cis-trans isomerase;


:

Pssm-ID: 459735  Cd Length: 94  Bit Score: 83.79  E-value: 5.96e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 103 GSSRPLKGQVVTVHLQMSLENGTRVQ----EEPELAFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGRSPY- 177
Cdd:pfam00254   1 GPEKAKKGDRVTVHYTGTLEDGTVFDssydRGKPFEFTLGSGQVIPGWDEGLVGMKVGEKRKLTIPPELAYGEEGLAGPv 80

                          90
                  ....*....|....
gi 1039783175 178 IPPHAALCLEVTLK 191
Cdd:pfam00254  81 IPPNATLVFEVELL 94
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
209-336 1.80e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.87  E-value: 1.80e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 209 ALANRkrecGNAHYQRADFVLAANSYDLAIKAITSNTKVdmtceeeeellqlkvkcLNNLAASQLKLDHYRAALRSCSQV 288
Cdd:COG0457    10 AYNNL----GLAYRRLGRYEEAIEDYEKALELDPDDAEA-----------------LYNLGLAYLRLGRYEEALADYEQA 68

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1039783175 289 LEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 336
Cdd:COG0457    69 LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNL 116
 
Name Accession Description Interval E-value
FKBP_C pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase;
103-191 5.96e-20

FKBP-type peptidyl-prolyl cis-trans isomerase;


Pssm-ID: 459735  Cd Length: 94  Bit Score: 83.79  E-value: 5.96e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 103 GSSRPLKGQVVTVHLQMSLENGTRVQ----EEPELAFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGRSPY- 177
Cdd:pfam00254   1 GPEKAKKGDRVTVHYTGTLEDGTVFDssydRGKPFEFTLGSGQVIPGWDEGLVGMKVGEKRKLTIPPELAYGEEGLAGPv 80

                          90
                  ....*....|....
gi 1039783175 178 IPPHAALCLEVTLK 191
Cdd:pfam00254  81 IPPNATLVFEVELL 94
FkpA COG0545
FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein ...
 92-190 7.77e-15

FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440311 [Multi-domain]  Cd Length: 104  Bit Score: 69.83  E-value: 7.77e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175  92 LRMKTLVPGpKGSSrPLKGQVVTVHLQMSLENGT----RVQEEPELAFTLGDCDVIQALDLSVPLMDVGETAMVTADSKY 167
Cdd:COG0545     1 LQYKVLKEG-TGAK-PKAGDTVTVHYTGTLLDGTvfdsSYDRGEPATFPLGVGQVIPGWDEGLQGMKVGGKRRLVIPPEL 78

                          90       100
                  ....*....|....*....|...
gi 1039783175 168 CYGPQGRSPYIPPHAALCLEVTL 190
Cdd:COG0545    79 AYGERGAGGVIPPNSTLVFEVEL 101
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
209-336 1.80e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.87  E-value: 1.80e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 209 ALANRkrecGNAHYQRADFVLAANSYDLAIKAITSNTKVdmtceeeeellqlkvkcLNNLAASQLKLDHYRAALRSCSQV 288
Cdd:COG0457    10 AYNNL----GLAYRRLGRYEEAIEDYEKALELDPDDAEA-----------------LYNLGLAYLRLGRYEEALADYEQA 68

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1039783175 289 LEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 336
Cdd:COG0457    69 LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNL 116
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 267-329 2.16e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 46.08  E-value: 2.16e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039783175 267 NLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 329
Cdd:cd24142     5 EKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDG 67
TPR_19 pfam14559
Tetratricopeptide repeat;
278-339 2.26e-05

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 41.80  E-value: 2.26e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039783175 278 YRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKL 339
Cdd:pfam14559   4 YAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 265-342 7.49e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 7.49e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039783175 265 LNNLAASQLKLDHYRAaLRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKK 342
Cdd:TIGR02917 807 LNNLAWLYLELKDPRA-LEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLA 883
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 296-329 9.64e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 39.35  E-value: 9.64e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1039783175  296 IKALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 329
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
FKBP_C pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase;
103-191 5.96e-20

FKBP-type peptidyl-prolyl cis-trans isomerase;


Pssm-ID: 459735  Cd Length: 94  Bit Score: 83.79  E-value: 5.96e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 103 GSSRPLKGQVVTVHLQMSLENGTRVQ----EEPELAFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGRSPY- 177
Cdd:pfam00254   1 GPEKAKKGDRVTVHYTGTLEDGTVFDssydRGKPFEFTLGSGQVIPGWDEGLVGMKVGEKRKLTIPPELAYGEEGLAGPv 80

                          90
                  ....*....|....
gi 1039783175 178 IPPHAALCLEVTLK 191
Cdd:pfam00254  81 IPPNATLVFEVELL 94
FkpA COG0545
FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein ...
 92-190 7.77e-15

FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440311 [Multi-domain]  Cd Length: 104  Bit Score: 69.83  E-value: 7.77e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175  92 LRMKTLVPGpKGSSrPLKGQVVTVHLQMSLENGT----RVQEEPELAFTLGDCDVIQALDLSVPLMDVGETAMVTADSKY 167
Cdd:COG0545     1 LQYKVLKEG-TGAK-PKAGDTVTVHYTGTLLDGTvfdsSYDRGEPATFPLGVGQVIPGWDEGLQGMKVGGKRRLVIPPEL 78

                          90       100
                  ....*....|....*....|...
gi 1039783175 168 CYGPQGRSPYIPPHAALCLEVTL 190
Cdd:COG0545    79 AYGERGAGGVIPPNSTLVFEVEL 101
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
209-336 1.80e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.87  E-value: 1.80e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 209 ALANRkrecGNAHYQRADFVLAANSYDLAIKAITSNTKVdmtceeeeellqlkvkcLNNLAASQLKLDHYRAALRSCSQV 288
Cdd:COG0457    10 AYNNL----GLAYRRLGRYEEAIEDYEKALELDPDDAEA-----------------LYNLGLAYLRLGRYEEALADYEQA 68

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1039783175 289 LEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 336
Cdd:COG0457    69 LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNL 116
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 209-336 4.29e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 64.63  E-value: 4.29e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 209 ALANRKRECGNAHYQRADFVLAANSYDLAIKAITSNTKVdmtceeeeellqlkvkcLNNLAASQLKLDHYRAALRSCSQV 288
Cdd:COG3914    76 LLAALLELAALLLQALGRYEEALALYRRALALNPDNAEA-----------------LFNLGNLLLALGRLEEALAALRRA 138

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1039783175 289 LEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 336
Cdd:COG3914   139 LALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNL 186
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
209-336 7.06e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 61.95  E-value: 7.06e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 209 ALANRkrecGNAHYQRADFVLAANSYDLAIKAITSNtkvdmtceeeeellqlkVKCLNNLAASQLKLDHYRAALRSCSQV 288
Cdd:COG0457    44 ALYNL----GLAYLRLGRYEEALADYEQALELDPDD-----------------AEALNNLGLALQALGRYEEALEDYDKA 102

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1039783175 289 LEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 336
Cdd:COG0457   103 LELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNL 150
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 218-336 1.30e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.09  E-value: 1.30e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 218 GNAHYQRADFVLAANSYDLAIKAITSNTKVdmtceeeeellqlkvkcLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIK 297
Cdd:COG3914   119 GNLLLALGRLEEALAALRRALALNPDFAEA-----------------YLNLGEALRRLGRLEEAIAALRRALELDPDNAE 181

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1039783175 298 ALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 336
Cdd:COG3914   182 ALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 265-358 4.03e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 57.51  E-value: 4.03e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 265 LNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSkLVKKRA 344
Cdd:COG4783     7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLG-LALLKA 85

                          90
                  ....*....|....
gi 1039783175 345 AQRSTETALYRKML 358
Cdd:COG4783    86 GDYDEALALLEKAL 99
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 218-329 3.40e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 54.63  E-value: 3.40e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 218 GNAHYQRADFVLAANSYDLAIKAITSNTKVdmtceeeeellqlkvkcLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIK 297
Cdd:COG4235    24 GRAYLRLGRYDEALAAYEKALRLDPDNADA-----------------LLDLAEALLAAGDTEEAEELLERALALDPDNPE 86

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1039783175 298 ALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 329
Cdd:COG4235    87 ALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 265-358 1.61e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 52.89  E-value: 1.61e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 265 LNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLvKKRA 344
Cdd:COG4783    41 FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARA-YRAL 119

                          90
                  ....*....|....
gi 1039783175 345 AQRSTETALYRKML 358
Cdd:COG4783   120 GRPDEAIAALEKAL 133
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
209-329 1.80e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 54.54  E-value: 1.80e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 209 ALANRkrecGNAHYQRADFVLAANSYDLAIKAITSNTKVdmtceeeeellqlkvkcLNNLAASQLKLDHYRAALRSCSQV 288
Cdd:COG4785    75 LYYER----GVAYDSLGDYDLAIADFDQALELDPDLAEA-----------------YNNRGLAYLLLGDYDAALEDFDRA 133

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1039783175 289 LEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 329
Cdd:COG4785   134 LELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPND 174
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 220-361 1.83e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 53.43  E-value: 1.83e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 220 AHYQRADFVLAANSYDLAIKAITSNTKVDMTCEEEEELLQLKVKCLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKAL 299
Cdd:COG5010    12 LYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELY 91

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039783175 300 FRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKRAAQRSTETALYRKMLGNP 361
Cdd:COG5010    92 YNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 267-336 2.07e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 52.32  E-value: 2.07e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 267 NLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 336
Cdd:COG4235    22 LLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLL 91
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
272-339 3.05e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 50.94  E-value: 3.05e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039783175 272 QLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPiLRAALKLEPSNKTIHAELSKL 339
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAEL 68
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 264-362 5.55e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.58  E-value: 5.55e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 264 CLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKR 343
Cdd:COG2956   146 AYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKL 225

                          90
                  ....*....|....*....
gi 1039783175 344 AAQRSTETALYRKMLGNPS 362
Cdd:COG2956   226 GDPEEALELLRKALELDPS 244
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 268-366 1.40e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 53.46  E-value: 1.40e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 268 LAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVkkRAAQR 347
Cdd:COG3914    84 AALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEAL--RRLGR 161

                          90       100
                  ....*....|....*....|.
gi 1039783175 348 STE-TALYRKMLG-NPSRLPA 366
Cdd:COG3914   162 LEEaIAALRRALElDPDNAEA 182
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 210-358 3.80e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 51.27  E-value: 3.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 210 LANRKRECGNAHYQRADFVLAANSYDLAIKAITSNTKVDMTCeeeeellqlkVKCLNNLAASQLKLDHYRAALRSCSQVL 289
Cdd:COG2956   136 LLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDC----------ARALLLLAELYLEQGDYEEAIAALERAL 205

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039783175 290 EHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNktihAELSKLVKKRAAQRSTETA--LYRKML 358
Cdd:COG2956   206 EQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD----DLLLALADLLERKEGLEAAlaLLERQL 272
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 222-360 5.93e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.50  E-value: 5.93e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 222 YQRADFVLAANSYDLAIKAITSNTKVDmtceeeeellQLKVKCLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFR 301
Cdd:COG2956    12 YFKGLNYLLNGQPDKAIDLLEEALELD----------PETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLE 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039783175 302 KGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKL------------VKKRAAQRSTETALYRKMLGN 360
Cdd:COG2956    82 LAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIyeqegdwekaieVLERLLKLGPENAHAYCELAE 152
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
209-354 6.17e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 50.39  E-value: 6.17e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 209 ALANRkrecGNAHYQRADFVLAANSYDLAIKAITSNtkvdmtceeeeellqlkVKCLNNLAASQLKLDHYRAALRSCSQV 288
Cdd:COG0457    78 ALNNL----GLALQALGRYEEALEDYDKALELDPDD-----------------AEALYNLGLALLELGRYDEAIEAYERA 136

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039783175 289 LEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKRAAQRSTETALY 354
Cdd:COG0457   137 LELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLA 202
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
265-328 7.63e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 47.09  E-value: 7.63e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039783175 265 LNNLAASQLKLDHYRAALRsCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPS 328
Cdd:COG3063    29 LNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 265-339 7.65e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.11  E-value: 7.65e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039783175 265 LNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKL 339
Cdd:COG2956    79 LLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAEL 153
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 265-329 3.06e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 46.34  E-value: 3.06e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039783175 265 LNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 329
Cdd:COG4783    75 RLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 265-346 5.37e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 44.98  E-value: 5.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 265 LNNLAASQLKLDHYRAALRSCSQVLEHQPDNIK---ALFRKGKVLAQQGEYSEAIPILRAALKLEPSnktihAELSKLVK 341
Cdd:COG1729    33 LYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDYDKARATLEELIKKYPD-----SEAAKEAR 107


                  ....*
gi 1039783175 342 KRAAQ 346
Cdd:COG1729   108 ARLAR 112
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 280-336 6.23e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.38  E-value: 6.23e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1039783175 280 AALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 336
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDL 57
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 210-366 1.59e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 46.26  E-value: 1.59e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 210 LANRKRECGNAHYQRADFVLAANSYDLAIKAITSNTKVDmtceeeeellQLKVKCLNNLAASQLKLDHYRAALRSCSQVL 289
Cdd:COG2956    68 LLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELD----------PDDAEALRLLAEIYEQEGDWEKAIEVLERLL 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 290 EHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLvkkRAAQRSTETAL--YRKMLG-NPSRLPA 366
Cdd:COG2956   138 KLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAEL---YLEQGDYEEAIaaLERALEqDPDYLPA 214
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 267-329 2.16e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 46.08  E-value: 2.16e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039783175 267 NLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 329
Cdd:cd24142     5 EKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDG 67
TPR_19 pfam14559
Tetratricopeptide repeat;
278-339 2.26e-05

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 41.80  E-value: 2.26e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039783175 278 YRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKL 339
Cdd:pfam14559   4 YAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 265-342 7.49e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 7.49e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039783175 265 LNNLAASQLKLDHYRAaLRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKK 342
Cdd:TIGR02917 807 LNNLAWLYLELKDPRA-LEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLA 883
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 296-329 9.64e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 39.35  E-value: 9.64e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1039783175  296 IKALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 329
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
296-329 1.06e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.94  E-value: 1.06e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1039783175 296 IKALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 329
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
289-336 2.21e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 42.30  E-value: 2.21e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1039783175 289 LEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 336
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNL 48
TPR_11 pfam13414
TPR repeat;
303-342 2.89e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 38.22  E-value: 2.89e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1039783175 303 GKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKK 342
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYK 40
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 189-366 3.56e-04

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 42.66  E-value: 3.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 189 TLKTAEDGPDLEM-----LSGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAitsntKVDMTCeeeeellqlkvk 263
Cdd:TIGR00990 100 PVEPADELPEIDEssvanLSEEERKKYAAKLKEKGNKAYRNKDFNKAIKLYSKAIEC-----KPDPVY------------ 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 264 cLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRA-ALKLEPSNKTIHAELSKLVKK 342
Cdd:TIGR00990 163 -YSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLGKYADALLDLTAsCIIDGFRNEQSAQAVERLLKK 241

                         170       180
                  ....*....|....*....|....
gi 1039783175 343 RAaqrstETALYRKMLGNPSRLPA 366
Cdd:TIGR00990 242 FA-----ESKAKEILETKPENLPS 260
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 262-367 4.54e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.38  E-value: 4.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 262 VKCLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKL---EPSNKTIHAELSK 338
Cdd:TIGR02917 193 VDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKapnSPLAHYLKALVDF 272

                          90       100
                  ....*....|....*....|....*....
gi 1039783175 339 LVKKRAAQRSTETALYRKmlgNPSRLPAK 367
Cdd:TIGR02917 273 QKKNYEDARETLQDALKS---APEYLPAL 298
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 297-327 6.34e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 36.73  E-value: 6.34e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1039783175 297 KALFRKGKVLAQQGEYSEAIPILRAALKLEP 327
Cdd:pfam07719   2 EALYNLGLAYYKLGDYEEALEAYEKALELDP 32
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 218-353 1.49e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.84  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 218 GNAHYQRADFVLAANSYDLAIKAITSNtkvdmtceeeeellQLKVKclnnLAASQLKLDHYRAALRSCSQVLEHQPDNIK 297
Cdd:TIGR02917 710 GDLYLRQKDYPAAIQAYRKALKRAPSS--------------QNAIK----LHRALLASGNTAEAVKTLEAWLKTHPNDAV 771

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1039783175 298 ALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKRAAQRSTETAL 353
Cdd:TIGR02917 772 LRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKDPRALEYAE 827
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 271-353 1.82e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.66  E-value: 1.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039783175 271 SQLKLDHYRAALRSCSQVLEHQPDNI---KALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKRAAQR 347
Cdd:COG1729     2 ALLKAGDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLELG 81


                  ....*.
gi 1039783175 348 STETAL 353
Cdd:COG1729    82 DYDKAR 87
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 267-329 1.89e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 36.55  E-value: 1.89e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039783175 267 NLAASQLKLDHYRAALRSCSQVLEHQ---PDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 329
Cdd:pfam13432   2 ALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 262-295 2.17e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.50  E-value: 2.17e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1039783175  262 VKCLNNLAASQLKLDHYRAALRSCSQVLEHQPDN 295
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_8 pfam13181
Tetratricopeptide repeat;
296-328 3.37e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 34.68  E-value: 3.37e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1039783175 296 IKALFRKGKVLAQQGEYSEAIPILRAALKLEPS 328
Cdd:pfam13181   1 AEAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 268-329 4.99e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.30  E-value: 4.99e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039783175 268 LAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 329
Cdd:TIGR02917 607 LGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDN 668
TPR_1 pfam00515
Tetratricopeptide repeat;
262-295 5.53e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.32  E-value: 5.53e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1039783175 262 VKCLNNLAASQLKLDHYRAALRSCSQVLEHQPDN 295
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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