KATNB1-like protein 1 isoform X1 [Homo sapiens]
Protein Classification
Katanin_con80 domain-containing protein( domain architecture ID 10621878)
Katanin_con80 domain-containing protein
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||
| Katanin_con80 | pfam13925 | con80 domain of Katanin; The con80 domain of katanin is the C-terminal region of the protein ... |
149-300 | 6.01e-50 | ||||
con80 domain of Katanin; The con80 domain of katanin is the C-terminal region of the protein that binds to the N-terminal domain of katanin-p60, the catalytic ATPase. The complex associates with a specific subregion of the mitotic spindle leading to increased microtubule disassembly and targeting of p60 to the spindle poles. The assembly and function of the mitotic spindle requires the activity of a number of microtubule-binding proteins. Katanin, a heterodimeric microtubule-severing ATPase, is found localized at mitotic spindle poles. A proposed model is that katanin is targeted to spindle poles through a combination of direct microtubule binding by the p60 subunit and through interactions between the WD40 domain and an unknown protein. : Pssm-ID: 464044 Cd Length: 160 Bit Score: 162.78 E-value: 6.01e-50
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| Name | Accession | Description | Interval | E-value | ||||
| Katanin_con80 | pfam13925 | con80 domain of Katanin; The con80 domain of katanin is the C-terminal region of the protein ... |
149-300 | 6.01e-50 | ||||
con80 domain of Katanin; The con80 domain of katanin is the C-terminal region of the protein that binds to the N-terminal domain of katanin-p60, the catalytic ATPase. The complex associates with a specific subregion of the mitotic spindle leading to increased microtubule disassembly and targeting of p60 to the spindle poles. The assembly and function of the mitotic spindle requires the activity of a number of microtubule-binding proteins. Katanin, a heterodimeric microtubule-severing ATPase, is found localized at mitotic spindle poles. A proposed model is that katanin is targeted to spindle poles through a combination of direct microtubule binding by the p60 subunit and through interactions between the WD40 domain and an unknown protein. Pssm-ID: 464044 Cd Length: 160 Bit Score: 162.78 E-value: 6.01e-50
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| Name | Accession | Description | Interval | E-value | ||||
| Katanin_con80 | pfam13925 | con80 domain of Katanin; The con80 domain of katanin is the C-terminal region of the protein ... |
149-300 | 6.01e-50 | ||||
con80 domain of Katanin; The con80 domain of katanin is the C-terminal region of the protein that binds to the N-terminal domain of katanin-p60, the catalytic ATPase. The complex associates with a specific subregion of the mitotic spindle leading to increased microtubule disassembly and targeting of p60 to the spindle poles. The assembly and function of the mitotic spindle requires the activity of a number of microtubule-binding proteins. Katanin, a heterodimeric microtubule-severing ATPase, is found localized at mitotic spindle poles. A proposed model is that katanin is targeted to spindle poles through a combination of direct microtubule binding by the p60 subunit and through interactions between the WD40 domain and an unknown protein. Pssm-ID: 464044 Cd Length: 160 Bit Score: 162.78 E-value: 6.01e-50
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