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Conserved domains on  [gi|1034585177|ref|XP_016876320|]
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cell division cycle protein 16 homolog isoform X3 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ANAPC3 pfam12895
Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of ...
 15-94 4.08e-21

Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20.


:

Pssm-ID: 463743 [Multi-domain]  Cd Length: 82  Bit Score: 87.31  E-value: 4.08e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177  15 DQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLTAQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEHQQALDVLD 94
Cdd:pfam12895   1 DQHQYKNAIFLAERLLAAEPESPEDAYLLAQCLFLNGQYKRAYELLRKAKLNGSSLGCRYLFAQCLLKLKKYDEALDALG 80
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
373-522 7.95e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.27  E-value: 7.95e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 373 YIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEkikaignevTVDKWEPLLNNLG 452
Cdd:COG0457    13 NLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALE---------LDPDDAEALNNLG 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 453 HVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHC 522
Cdd:COG0457    84 LALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIA 153
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 275-440 6.08e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 55.38  E-value: 6.08e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 275 LVELNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAM 354
Cdd:COG3914    88 LQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEE-ALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAI 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 355 AAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKwFLDALEKIKA 434
Cdd:COG3914   167 AALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDR-FEELLAALAR 245


                  ....*.
gi 1034585177 435 IGNEVT 440
Cdd:COG3914   246 GPSELS 251
 
Name Accession Description Interval E-value
ANAPC3 pfam12895
Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of ...
 15-94 4.08e-21

Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20.


Pssm-ID: 463743 [Multi-domain]  Cd Length: 82  Bit Score: 87.31  E-value: 4.08e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177  15 DQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLTAQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEHQQALDVLD 94
Cdd:pfam12895   1 DQHQYKNAIFLAERLLAAEPESPEDAYLLAQCLFLNGQYKRAYELLRKAKLNGSSLGCRYLFAQCLLKLKKYDEALDALG 80
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
373-522 7.95e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.27  E-value: 7.95e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 373 YIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEkikaignevTVDKWEPLLNNLG 452
Cdd:COG0457    13 NLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALE---------LDPDDAEALNNLG 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 453 HVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHC 522
Cdd:COG0457    84 LALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIA 153
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 275-440 6.08e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 55.38  E-value: 6.08e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 275 LVELNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAM 354
Cdd:COG3914    88 LQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEE-ALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAI 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 355 AAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKwFLDALEKIKA 434
Cdd:COG3914   167 AALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDR-FEELLAALAR 245


                  ....*.
gi 1034585177 435 IGNEVT 440
Cdd:COG3914   246 GPSELS 251
TPR_12 pfam13424
Tetratricopeptide repeat;
447-511 1.64e-07

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 48.54  E-value: 1.64e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034585177 447 LLNNLGHVCRKLKKYAEALDYHRQALVLI--------PQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRD 511
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 3-129 3.34e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 49.23  E-value: 3.34e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177   3 LERLRKRVRQ--------------YLDQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLTAQYHRAAHAL-RSRKLDK 67
Cdd:COG4235     3 IARLRQALAAnpndaegwlllgraYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLeRALALDP 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034585177  68 LYEACRYLAARCHYAAKEHQQALDvldmeepinkrLFEKYLKDEsgfkDPSSDWEMSQSSIK 129
Cdd:COG4235    83 DNPEALYLLGLAAFQQGDYAEAIA-----------AWQKLLALL----PADAPARLLEASIA 129
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 341-508 7.56e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.93  E-value: 7.56e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 341 GHSFAVESEHDQAMAAYFTAAQLMKGCHLPMlYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKT 420
Cdd:TIGR02917 710 GDLYLRQKDYPAAIQAYRKALKRAPSSQNAI-KLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDK 788

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 421 AEKWFLDALEKikAIGNEVTvdkweplLNNLGHVCRKLKKyAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVD 500
Cdd:TIGR02917 789 AIKHYQTVVKK--APDNAVV-------LNNLAWLYLELKD-PRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALP 858


                  ....*...
gi 1034585177 501 YFHTALGL 508
Cdd:TIGR02917 859 LLRKAVNI 866
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 134-502 8.24e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.93  E-value: 8.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 134 LLRGKIYDALDNRTLATYSYKEALKLD-----VYCFEAFDLLTSHHMLTAQEEKE-LLESLPLSKLCNEEQELLRFlfen 207
Cdd:TIGR02917 197 LLKGDLLLSLGNIELALAAYRKAIALRpnniaVLLALATILIEAGEFEEAEKHADaLLKKAPNSPLAHYLKALVDF---- 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 208 KLKKYNKPSETVIpESVDGLQENLDVVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVELNKANELFYL 287
Cdd:TIGR02917 273 QKKNYEDARETLQ-DALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIAT 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 288 SHKLVDLYPSNPVSWFAVGCYYLMVGhKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQL---- 363
Cdd:TIGR02917 352 LSPALGLDPDDPAALSLLGEAYLALG-DFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLdpel 430

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 364 ------------------------------MKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAF 413
Cdd:TIGR02917 431 gradlllilsylrsgqfdkalaaakklekkQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDI 510

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 414 QNGEWKTAEKWFLDAL----EKIKAI----------GNEVTVDKW------------EPLLnNLGHVCRKLKKYAEALDY 467
Cdd:TIGR02917 511 QEGNPDDAIQRFEKVLtidpKNLRAIlalaglylrtGNEEEAVAWlekaaelnpqeiEPAL-ALAQYYLGKGQLKKALAI 589

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 1034585177 468 HRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYF 502
Cdd:TIGR02917 590 LNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSF 624
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 448-478 1.08e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 39.35  E-value: 1.08e-04
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1034585177  448 LNNLGHVCRKLKKYAEALDYHRQALVLIPQN 478
Cdd:smart00028   4 LYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 461-508 7.47e-03

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 37.73  E-value: 7.47e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1034585177 461 YAEALDYHRQALVLiPQNASTYSAI----GYIHSLMGNFENAVDYFHTALGL 508
Cdd:PRK02603   51 YAEALENYEEALKL-EEDPNDRSYIlynmGIIYASNGEHDKALEYYHQALEL 101
 
Name Accession Description Interval E-value
ANAPC3 pfam12895
Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of ...
 15-94 4.08e-21

Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20.


Pssm-ID: 463743 [Multi-domain]  Cd Length: 82  Bit Score: 87.31  E-value: 4.08e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177  15 DQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLTAQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEHQQALDVLD 94
Cdd:pfam12895   1 DQHQYKNAIFLAERLLAAEPESPEDAYLLAQCLFLNGQYKRAYELLRKAKLNGSSLGCRYLFAQCLLKLKKYDEALDALG 80
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
373-522 7.95e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.27  E-value: 7.95e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 373 YIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEkikaignevTVDKWEPLLNNLG 452
Cdd:COG0457    13 NLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALE---------LDPDDAEALNNLG 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 453 HVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHC 522
Cdd:COG0457    84 LALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIA 153
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
329-512 8.99e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.27  E-value: 8.99e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 329 LEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEV 408
Cdd:COG0457     3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 409 GVVAFQNGEWKTAEKWFLDALEKikaignevtVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYI 488
Cdd:COG0457    83 GLALQALGRYEEALEDYDKALEL---------DPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIA 153

                         170       180
                  ....*....|....*....|....
gi 1034585177 489 HSLMGNFENAVDYFHTALGLRRDD 512
Cdd:COG0457   154 LEKLGRYEEALELLEKLEAAALAA 177
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 366-512 5.43e-14

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 69.07  E-value: 5.43e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 366 GCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEkikaignevtVDKWE 445
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALE----------LDPDE 71

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034585177 446 P-LLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDD 512
Cdd:COG4783    72 PeARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 301-538 2.22e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 70.53  E-value: 2.22e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 301 SWFAVGCYYLMVGhKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGL 380
Cdd:COG2956    10 GWYFKGLNYLLNG-QPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLK 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 381 TNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAekwfLDALEKIKAIGnevtvDKWEPLLNNLGHVCRKLKK 460
Cdd:COG2956    89 AGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKA----IEVLERLLKLG-----PENAHAYCELAELYLEQGD 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034585177 461 YAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIEMyIGDSEAYIGNLK 538
Cdd:COG2956   160 YDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEK-LGDPEEALELLR 236
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 381-533 3.92e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 71.95  E-value: 3.92e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 381 TNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEKikaignevtVDKWEPLLNNLGHVCRKLKK 460
Cdd:COG3914    91 LGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALAL---------NPDFAEAYLNLGEALRRLGR 161

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034585177 461 YAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIeMYIGDSEAY 533
Cdd:COG3914   162 LEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFAL-RQACDWEVY 233
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 277-532 5.07e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 69.37  E-value: 5.07e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 277 ELNKANELFylsHKLVDLYPSNPVSWFAVGCYYLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAA 356
Cdd:COG2956    23 QPDKAIDLL---EEALELDPETVEAHLALGNLYRRRGEYDR-AIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEEL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 357 YFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEKIKaig 436
Cdd:COG2956    99 LEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDP--- 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 437 nevtvdKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFsV 516
Cdd:COG2956   176 ------DCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDL-L 248

                         250
                  ....*....|....*.
gi 1034585177 517 TMLGHCIEMYIGDSEA 532
Cdd:COG2956   249 LALADLLERKEGLEAA 264
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
395-522 1.17e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 67.72  E-value: 1.17e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 395 LSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEkikaignevtVDKWEP-LLNNLGHVCRKLKKYAEALDYHRQALV 473
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALE----------LDPDDAeALYNLGLAYLRLGRYEEALADYEQALE 70

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1034585177 474 LIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHC 522
Cdd:COG0457    71 LDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLA 119
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 290-506 3.04e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 63.98  E-value: 3.04e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 290 KLVDLYPSNPVSWFAVGCYYLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHL 369
Cdd:COG2956    67 KLLERDPDRAEALLELAQDYLKAGLLDR-AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAH 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 370 PMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEKikaignevtVDKWEPLLN 449
Cdd:COG2956   146 AYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQ---------DPDYLPALP 216

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034585177 450 NLGHVCRKLKKYAEALDYHRQALVLIPQNASTYsAIGYIHSLMGNFENAVDYFHTAL 506
Cdd:COG2956   217 RLAELYEKLGDPEEALELLRKALELDPSDDLLL-ALADLLERKEGLEAALALLERQL 272
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 349-524 6.96e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.55  E-value: 6.96e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 349 EHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDA 428
Cdd:COG3914    93 RYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRA 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 429 LEkikaigneVTVDKWEpLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGL 508
Cdd:COG3914   173 LE--------LDPDNAE-ALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAAL 243

                         170
                  ....*....|....*.
gi 1034585177 509 RRDDTFSVTMLGHCIE 524
Cdd:COG3914   244 ARGPSELSPFALLYLP 259
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 369-520 2.40e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.59  E-value: 2.40e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 369 LPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEKikaignevtVDKWEPLL 448
Cdd:COG2956     9 LGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLER---------DPDRAEAL 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034585177 449 NNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLG 520
Cdd:COG2956    80 LELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELA 151
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
411-511 2.90e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 51.32  E-value: 2.90e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 411 VAFQNGEWKTAEKWFLDALEKIKAIGNevtvdkwepLLNNLGHVCRKLKKYAEALDYhRQALVLIPQNASTYSAIGYIHS 490
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNAD---------ALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLL 70

                          90       100
                  ....*....|....*....|.
gi 1034585177 491 LMGNFENAVDYFHTALGLRRD 511
Cdd:COG3063    71 ELGDYDEALAYLERALELDPS 91
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
290-479 4.78e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 54.24  E-value: 4.78e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 290 KLVDLYPSNPVSWFAVGCYYLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHL 369
Cdd:COG0457    33 KALELDPDDAEALYNLGLAYLRLGRYEE-ALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAE 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 370 PMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEPLLN 449
Cdd:COG0457   112 ALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALA 191

                         170       180       190
                  ....*....|....*....|....*....|
gi 1034585177 450 NLGHVCRKLKKYAEALDYHRQALVLIPQNA 479
Cdd:COG0457   192 AAEVLLALLLALEQALRKKLAILTLAALAE 221
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 275-440 6.08e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 55.38  E-value: 6.08e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 275 LVELNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAM 354
Cdd:COG3914    88 LQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEE-ALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAI 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 355 AAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKwFLDALEKIKA 434
Cdd:COG3914   167 AALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDR-FEELLAALAR 245


                  ....*.
gi 1034585177 435 IGNEVT 440
Cdd:COG3914   246 GPSELS 251
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 404-538 1.03e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.96  E-value: 1.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 404 VMHEVGVVAFQNGEWKTAEKWFLDALEKikaignevtVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYS 483
Cdd:COG4783     6 ALYALAQALLLAGDYDEAEALLEKALEL---------DPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARL 76

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1034585177 484 AIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIEMyIGDSEAYIGNLK 538
Cdd:COG4783    77 NLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRA-LGRPDEAIAALE 130
TPR_12 pfam13424
Tetratricopeptide repeat;
447-511 1.64e-07

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 48.54  E-value: 1.64e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034585177 447 LLNNLGHVCRKLKKYAEALDYHRQALVLI--------PQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRD 511
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 302-431 2.59e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.81  E-value: 2.59e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 302 WFAVGCYYLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLT 381
Cdd:COG4783     7 LYALAQALLLAGDYDE-AEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1034585177 382 NNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEK 431
Cdd:COG4783    86 GDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 3-129 3.34e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 49.23  E-value: 3.34e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177   3 LERLRKRVRQ--------------YLDQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLTAQYHRAAHAL-RSRKLDK 67
Cdd:COG4235     3 IARLRQALAAnpndaegwlllgraYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLeRALALDP 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034585177  68 LYEACRYLAARCHYAAKEHQQALDvldmeepinkrLFEKYLKDEsgfkDPSSDWEMSQSSIK 129
Cdd:COG4235    83 DNPEALYLLGLAAFQQGDYAEAIA-----------AWQKLLALL----PADAPARLLEASIA 129
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 378-476 6.60e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 49.19  E-value: 6.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 378 YGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEKIKAignevtvdkWEPLLNNLGHVCRK 457
Cdd:COG5010    64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPD---------NPNAYSNLAALLLS 134

                          90
                  ....*....|....*....
gi 1034585177 458 LKKYAEALDYHRQALVLIP 476
Cdd:COG5010   135 LGQDDEAKAALQRALGTSP 153
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 336-430 2.05e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 47.31  E-value: 2.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 336 AWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQN 415
Cdd:COG4235    19 GWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQ 98

                          90
                  ....*....|....*
gi 1034585177 416 GEWKTAEKWFLDALE 430
Cdd:COG4235    99 GDYAEAIAAWQKLLA 113
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 393-512 2.61e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.92  E-value: 2.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 393 QALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEkikaignevtVDKWEP-LLNNLGHVCRKLKKYAEALDYHRQA 471
Cdd:COG4235     8 QALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALR----------LDPDNAdALLDLAEALLAAGDTEEAEELLERA 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1034585177 472 LVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDD 512
Cdd:COG4235    78 LALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 410-508 2.69e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.26  E-value: 2.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 410 VVAFQNGEWKTAEKWFLDALEKIKaignevtvdKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIH 489
Cdd:COG5010    62 NLYNKLGDFEESLALLEQALQLDP---------NNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALL 132

                          90
                  ....*....|....*....
gi 1034585177 490 SLMGNFENAVDYFHTALGL 508
Cdd:COG5010   133 LSLGQDDEAKAALQRALGT 151
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 454-520 2.82e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.26  E-value: 2.82e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034585177 454 VCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLG 520
Cdd:COG5010    63 LYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLA 129
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 341-508 7.56e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.93  E-value: 7.56e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 341 GHSFAVESEHDQAMAAYFTAAQLMKGCHLPMlYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKT 420
Cdd:TIGR02917 710 GDLYLRQKDYPAAIQAYRKALKRAPSSQNAI-KLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDK 788

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 421 AEKWFLDALEKikAIGNEVTvdkweplLNNLGHVCRKLKKyAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVD 500
Cdd:TIGR02917 789 AIKHYQTVVKK--APDNAVV-------LNNLAWLYLELKD-PRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALP 858


                  ....*...
gi 1034585177 501 YFHTALGL 508
Cdd:TIGR02917 859 LLRKAVNI 866
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 134-502 8.24e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.93  E-value: 8.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 134 LLRGKIYDALDNRTLATYSYKEALKLD-----VYCFEAFDLLTSHHMLTAQEEKE-LLESLPLSKLCNEEQELLRFlfen 207
Cdd:TIGR02917 197 LLKGDLLLSLGNIELALAAYRKAIALRpnniaVLLALATILIEAGEFEEAEKHADaLLKKAPNSPLAHYLKALVDF---- 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 208 KLKKYNKPSETVIpESVDGLQENLDVVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVELNKANELFYL 287
Cdd:TIGR02917 273 QKKNYEDARETLQ-DALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIAT 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 288 SHKLVDLYPSNPVSWFAVGCYYLMVGhKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQL---- 363
Cdd:TIGR02917 352 LSPALGLDPDDPAALSLLGEAYLALG-DFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLdpel 430

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 364 ------------------------------MKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAF 413
Cdd:TIGR02917 431 gradlllilsylrsgqfdkalaaakklekkQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDI 510

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 414 QNGEWKTAEKWFLDAL----EKIKAI----------GNEVTVDKW------------EPLLnNLGHVCRKLKKYAEALDY 467
Cdd:TIGR02917 511 QEGNPDDAIQRFEKVLtidpKNLRAIlalaglylrtGNEEEAVAWlekaaelnpqeiEPAL-ALAQYYLGKGQLKKALAI 589

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 1034585177 468 HRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYF 502
Cdd:TIGR02917 590 LNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSF 624
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 375-520 1.11e-05

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 46.95  E-value: 1.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 375 GLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALekikAIGNEVTvdkwePLLNNLGHV 454
Cdd:TIGR02521  38 ALGYLEQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRAL----TLNPNNG-----DVLNNYGTF 108

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034585177 455 CRKLKKYAEALDYHRQALV--LIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDdtFSVTMLG 520
Cdd:TIGR02521 109 LCQQGKYEQAMQQFEQAIEdpLYPQPARSLENAGLCALKAGDFDKAEKYLTRALQIDPQ--RPESLLE 174
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 277-401 1.90e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.41  E-value: 1.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 277 ELNKANELFylsHKLVDLYPSNPVSWFAVGCYYLMVGhKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAA 356
Cdd:COG4783    19 DYDEAEALL---EKALELDPDNPEAFALLGEILLQLG-DLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALAL 94

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1034585177 357 YFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPED 401
Cdd:COG4783    95 LEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 308-430 2.67e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.57  E-value: 2.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 308 YYLMVGHKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLA 387
Cdd:COG5010    28 EAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEA 107

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1034585177 388 ERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALE 430
Cdd:COG5010   108 KEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 372-479 2.71e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.84  E-value: 2.71e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 372 LYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEkikaignevtVDKWEP-LLNN 450
Cdd:COG4235    21 LLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALA----------LDPDNPeALYL 90

                          90       100
                  ....*....|....*....|....*....
gi 1034585177 451 LGHVCRKLKKYAEALDYHRQALVLIPQNA 479
Cdd:COG4235    91 LGLAAFQQGDYAEAIAAWQKLLALLPADA 119
TPR_12 pfam13424
Tetratricopeptide repeat;
404-472 3.16e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 42.37  E-value: 3.16e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034585177 404 VMHEVGVVAFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEpLLNNLGHVCRKLKKYAEALDYHRQAL 472
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTAT-TLLNLGRLYLELGRYEEALELLERAL 72
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
349-506 3.20e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 45.29  E-value: 3.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 349 EHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDA 428
Cdd:COG4785    88 DYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKA 167

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034585177 429 LEKikaignevtvDKWEPLLNNLGHVCRKLKKYAEALDYHRQAlvlipqnastysaIGYIHSLMGNFENAVDYFHTAL 506
Cdd:COG4785   168 LEL----------DPNDPERALWLYLAERKLDPEKALALLLED-------------WATAYLLQGDTEEARELFKLAL 222
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 296-402 3.44e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.46  E-value: 3.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 296 PSNPVSWFAVGCYYLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIG 375
Cdd:COG4235    14 PNDAEGWLLLGRAYLRLGRYDE-ALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLG 92

                          90       100
                  ....*....|....*....|....*..
gi 1034585177 376 LEYGLTNNSKLAERFFSQALSIAPEDP 402
Cdd:COG4235    93 LAAFQQGDYAEAIAAWQKLLALLPADA 119
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 373-506 4.87e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.23  E-value: 4.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 373 YIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEkiKAIGNevtVDKWepllNNLG 452
Cdd:TIGR02917 130 LRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLT--ADPGN---VDAL----LLKG 200

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1034585177 453 HVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTAL 506
Cdd:TIGR02917 201 DLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALL 254
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
447-515 7.80e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 44.14  E-value: 7.80e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 447 LLNNLGHVCRKLKKYAEAL-DYhRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFS 515
Cdd:COG4785    75 LYYERGVAYDSLGDYDLAIaDF-DQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYA 143
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 448-478 1.08e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 39.35  E-value: 1.08e-04
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1034585177  448 LNNLGHVCRKLKKYAEALDYHRQALVLIPQN 478
Cdd:smart00028   4 LYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
448-478 1.41e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.94  E-value: 1.41e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1034585177 448 LNNLGHVCRKLKKYAEALDYHRQALVLIPQN 478
Cdd:pfam00515   4 LYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 450-520 1.56e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.53  E-value: 1.56e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034585177 450 NLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLG 520
Cdd:COG4235    22 LLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLG 92
COG3899 COG3899
Predicted ATPase [General function prediction only];
318-511 2.95e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 43.69  E-value: 2.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177  318 HAR--RYLSKATTLEKTYGPAWIAYgHsFAVESEHDQAMAAYFTAAQLMKGCHLPmlyigleygltnnsKLAERFFSQAL 395
Cdd:COG3899    669 HRRiaRALEARGPEPLEERLFELAH-H-LNRAGERDRAARLLLRAARRALARGAY--------------AEALRYLERAL 732

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177  396 SIAPEDPF------VMHEVGVVAFQNGEWKTAEKWFLDALEK--IKAIGNEVTVDKWEPL--LNNLGHVCRklKKYAEAL 465
Cdd:COG3899    733 ELLPPDPEeeyrlaLLLELAEALYLAGRFEEAEALLERALAAraLAALAALRHGNPPASAraYANLGLLLL--GDYEEAY 810

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1034585177  466 DYHRQALVLI------PQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRD 511
Cdd:COG3899    811 EFGELALALAerlgdrRLEARALFNLGFILHWLGPLREALELLREALEAGLE 862
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
454-521 6.99e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.00  E-value: 6.99e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034585177 454 VCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDyFHTALGLRRDDTFSVTMLGH 521
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAE 67
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 315-399 8.85e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.94  E-value: 8.85e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 315 KNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQA 394
Cdd:COG5010    69 DFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRA 148


                  ....*
gi 1034585177 395 LSIAP 399
Cdd:COG5010   149 LGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
13-94 1.37e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.23  E-value: 1.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177  13 YLDQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLTAQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEHQQALDV 92
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEKALKLDPNNAEALLNLAELLLELGDYDEALAY 81


                  ..
gi 1034585177  93 LD 94
Cdd:COG3063    82 LE 83
TPR_11 pfam13414
TPR repeat;
452-493 1.70e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.30  E-value: 1.70e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1034585177 452 GHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMG 493
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 2-93 2.21e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.10  E-value: 2.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177   2 NLERLRKRVRQYLDQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLTAQYHRAAHAL-RSRKLDKLYEACRYLAARCH 80
Cdd:COG2956   109 DAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALeKALKLDPDCARALLLLAELY 188

                          90
                  ....*....|...
gi 1034585177  81 YAAKEHQQALDVL 93
Cdd:COG2956   189 LEQGDYEEAIAAL 201
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 308-520 3.46e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.45  E-value: 3.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 308 YYLMVGHKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLA 387
Cdd:TIGR02917 167 QLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEA 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 388 ERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAekwfLDALEKIKAIGNEvtvdkWEPLLNNLGHVCRKLKKYAEALDY 467
Cdd:TIGR02917 247 EKHADALLKKAPNSPLAHYLKALVDFQKKNYEDA----RETLQDALKSAPE-----YLPALLLAGASEYQLGNLEQAYQY 317

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1034585177 468 HRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLG 520
Cdd:TIGR02917 318 LNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLG 370
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 3-160 3.63e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.86  E-value: 3.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177   3 LERLRKRVRQYLDQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLTAQYHRAAHAL-RSRKLDKLYEACRYLAARCHY 81
Cdd:COG4783     4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLhEALELDPDEPEARLNLGLALL 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034585177  82 AAKEHQQALdvldmeepinkRLFEKYLKdesgfKDPSSdwemsqssikSSICLLRGKIYDALDNRTLATYSYKEALKLD 160
Cdd:COG4783    84 KAGDYDEAL-----------ALLEKALK-----LDPEH----------PEAYLRLARAYRALGRPDEAIAALEKALELD 136
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 165-508 6.42e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.30  E-value: 6.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 165 EAFDLLTSHHMLTAQEEKELLESLPLSKLCNEEQELLRFLFENKLKKynKPSetvipesvdglqeNLDVVVSLAERHYYN 244
Cdd:TIGR02917 108 QVLDELPGKTLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAI--DPR-------------SLYAKLGLAQLALAE 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 245 CDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVELNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHArrylS 324
Cdd:TIGR02917 173 NRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAE----K 248

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 325 KATTLEKtygpawIAYGHSFAvesEHDQAMAAY-----------FTAAQLMKGCHLPMLYIG--LEYGLtNNSKLAERFF 391
Cdd:TIGR02917 249 HADALLK------KAPNSPLA---HYLKALVDFqkknyedaretLQDALKSAPEYLPALLLAgaSEYQL-GNLEQAYQYL 318

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 392 SQALSIAPEDPFVMHEVGVVAFQNGEwktaekwFLDALEKIKAIGNEVTVDKwePLLNNLGHVCRKLKKYAEALDYHRQA 471
Cdd:TIGR02917 319 NQILKYAPNSHQARRLLASIQLRLGR-------VDEAIATLSPALGLDPDDP--AALSLLGEAYLALGDFEKAAEYLAKA 389

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 1034585177 472 LVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGL 508
Cdd:TIGR02917 390 TELDPENAAARTQLGISKLSQGDPSEAIADLETAAQL 426
TPR_7 pfam13176
Tetratricopeptide repeat;
447-474 7.28e-03

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 34.44  E-value: 7.28e-03
                          10        20
                  ....*....|....*....|....*...
gi 1034585177 447 LLNNLGHVCRKLKKYAEALDYHRQALVL 474
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALAL 28
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 461-508 7.47e-03

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 37.73  E-value: 7.47e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1034585177 461 YAEALDYHRQALVLiPQNASTYSAI----GYIHSLMGNFENAVDYFHTALGL 508
Cdd:PRK02603   51 YAEALENYEEALKL-EEDPNDRSYIlynmGIIYASNGEHDKALEYYHQALEL 101
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 274-363 8.08e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.09  E-value: 8.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 274 TLVELNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQA 353
Cdd:COG4783    47 ILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDE-ALALLEKALKLDPEHPEAYLRLARAYRALGRPDEA 125

                          90
                  ....*....|
gi 1034585177 354 MAAYFTAAQL 363
Cdd:COG4783   126 IAALEKALEL 135
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
339-512 8.61e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 37.97  E-value: 8.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 339 AYGHSFAVESEHDQAMAAYFTAAQLMKGC-HLPMLYIGLE---YGLTNNSKLAERFFSQALSI-----APEDPFVMHEVG 409
Cdd:COG4785     1 LYALALALLLALALAAAAASKAAILLAALlFAAVLALAIAladLALALAAAALAAAALAAERIdralaLPDLAQLYYERG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585177 410 VVAFQNGEWKTAEKWFLDALEkikaignevTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIH 489
Cdd:COG4785    81 VAYDSLGDYDLAIADFDQALE---------LDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIAL 151

                         170       180
                  ....*....|....*....|...
gi 1034585177 490 SLMGNFENAVDYFHTALGLRRDD 512
Cdd:COG4785   152 YYLGRYELAIADLEKALELDPND 174
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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