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Conserved domains on  [gi|1034572959|ref|XP_016873006|]
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triokinase/FMN cyclase isoform X2 [Homo sapiens]

Protein Classification

dihydroxyacetone kinase family protein( domain architecture ID 11494183)

dihydroxyacetone kinase family protein such as human triokinase/FMN cyclase and Saccharomyces cerevisiae dihydroxyacetone kinases 1 and 2, which catalyze the phosphorylation of both dihydroxyacetone and glyceraldehyde

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
dak_ATP TIGR02361
dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of ...
 50-604 0e+00

dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of dihydroxyacetone kinase (also called glycerone kinase) that uses ATP (2.7.1.29) as the phosphate donor, rather than a phosphoprotein as in E. coli. This form is composed of a single chain with separable domains homologous to the K and L subunits of the E. coli enzyme, and is found in yeasts and other eukaryotes and in some bacteria, including Citrobacter freundii. The member from tomato has been shown to phosphorylate dihydroxyacetone, 3,4-dihydroxy-2-butanone, and some other aldoses and ketoses ().


:

Pssm-ID: 274097 [Multi-domain]  Cd Length: 574  Bit Score: 720.32  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959  50 KKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 129
Cdd:TIGR02361   1 KHFVNDPEHLVDDALKGLVAANPGLQLLESRKVVYRRDLN--KDKVSLISGGGSGHEPAHAGFVGKGMLTAAVAGDVFAS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 130 PAVGSILAAIRAVAQaGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLK--KAGRRGLCGTVLIH 207
Cdd:TIGR02361  79 PSTKQILAAIRAVVG-SEAGTLLIVKNYTGDRLNFGLAAEKAKAEGYNVEMVIVGDDVSVGRKKggLVGRRGLAGTVLVH 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 208 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGSKPTF-ELSADEVELGLGIHGEAGVRRIKMA-TADEIVK 285
Cdd:TIGR02361 158 KIAGAAAARGLSLAEVAKVAQAAADNLVTIGASLDHCHVPGETEAEpELKEDEMELGMGIHNEPGAKRISPIpSSDLVVQ 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 286 LMLDHMTNTTNA-SHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARAL-VGTFMSALEMPGISLTLL 363
Cdd:TIGR02361 238 LMLKKLLDETDKrSYVKFNEGDEVVLLVNNLGGVSNLELGIIADEVVEQLALHYNIIPVRIySGTFMTSLNGPGFSITLL 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 364 LVDE---PLLKLIDAETTAAAWPNVAAVSITGRKRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNA 440
Cdd:TIGR02361 318 NATEagkSILDLLDAPTEAPGWPVAAYSSKPWREKREVVSSSAPELIEETAVRSYDPQLVAAILESGCAALLELEPHLTK 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 441 LDRAAGDGDCGTTHSRAARAIQEWLK-EGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKAKTSLP---- 515
Cdd:TIGR02361 398 LDTKAGDGDCGSTLARGAEAILELLKsKKLPLNDPATLLAQISDVVEGVMGGTSGALYSIFFSAAAQSLKQNASKKeeit 477

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 516 --AWSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPgadllqvLTKAVKSAEAAAEATKNMEAGAGRASYI 593
Cdd:TIGR02361 478 peAWAAALKTALDALYKYTGARPGDRTMIDALQPFVEALEAGKSN-------LNAAVKAAEAGAEATKKMKAKAGRASYV 550

                         570
                  ....*....|..
gi 1034572959 594 SSARLEQ-PDPG 604
Cdd:TIGR02361 551 SSEALEGvPDPG 562
 
Name Accession Description Interval E-value
dak_ATP TIGR02361
dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of ...
 50-604 0e+00

dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of dihydroxyacetone kinase (also called glycerone kinase) that uses ATP (2.7.1.29) as the phosphate donor, rather than a phosphoprotein as in E. coli. This form is composed of a single chain with separable domains homologous to the K and L subunits of the E. coli enzyme, and is found in yeasts and other eukaryotes and in some bacteria, including Citrobacter freundii. The member from tomato has been shown to phosphorylate dihydroxyacetone, 3,4-dihydroxy-2-butanone, and some other aldoses and ketoses ().


Pssm-ID: 274097 [Multi-domain]  Cd Length: 574  Bit Score: 720.32  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959  50 KKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 129
Cdd:TIGR02361   1 KHFVNDPEHLVDDALKGLVAANPGLQLLESRKVVYRRDLN--KDKVSLISGGGSGHEPAHAGFVGKGMLTAAVAGDVFAS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 130 PAVGSILAAIRAVAQaGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLK--KAGRRGLCGTVLIH 207
Cdd:TIGR02361  79 PSTKQILAAIRAVVG-SEAGTLLIVKNYTGDRLNFGLAAEKAKAEGYNVEMVIVGDDVSVGRKKggLVGRRGLAGTVLVH 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 208 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGSKPTF-ELSADEVELGLGIHGEAGVRRIKMA-TADEIVK 285
Cdd:TIGR02361 158 KIAGAAAARGLSLAEVAKVAQAAADNLVTIGASLDHCHVPGETEAEpELKEDEMELGMGIHNEPGAKRISPIpSSDLVVQ 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 286 LMLDHMTNTTNA-SHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARAL-VGTFMSALEMPGISLTLL 363
Cdd:TIGR02361 238 LMLKKLLDETDKrSYVKFNEGDEVVLLVNNLGGVSNLELGIIADEVVEQLALHYNIIPVRIySGTFMTSLNGPGFSITLL 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 364 LVDE---PLLKLIDAETTAAAWPNVAAVSITGRKRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNA 440
Cdd:TIGR02361 318 NATEagkSILDLLDAPTEAPGWPVAAYSSKPWREKREVVSSSAPELIEETAVRSYDPQLVAAILESGCAALLELEPHLTK 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 441 LDRAAGDGDCGTTHSRAARAIQEWLK-EGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKAKTSLP---- 515
Cdd:TIGR02361 398 LDTKAGDGDCGSTLARGAEAILELLKsKKLPLNDPATLLAQISDVVEGVMGGTSGALYSIFFSAAAQSLKQNASKKeeit 477

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 516 --AWSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPgadllqvLTKAVKSAEAAAEATKNMEAGAGRASYI 593
Cdd:TIGR02361 478 peAWAAALKTALDALYKYTGARPGDRTMIDALQPFVEALEAGKSN-------LNAAVKAAEAGAEATKKMKAKAGRASYV 550

                         570
                  ....*....|..
gi 1034572959 594 SSARLEQ-PDPG 604
Cdd:TIGR02361 551 SSEALEGvPDPG 562
PRK14479 PRK14479
dihydroxyacetone kinase; Provisional
 50-604 3.18e-173

dihydroxyacetone kinase; Provisional


Pssm-ID: 237723 [Multi-domain]  Cd Length: 568  Bit Score: 504.35  E-value: 3.18e-173
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959  50 KKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 129
Cdd:PRK14479    2 KKLINDPSTFVEEMLEGFVAAHPDLVRLVPGGVVRRTPTP--EGKVAVVSGGGSGHEPAFAGYVGPGMLDAAVCGNVFTS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 130 PAVGSILAAIRAVAQAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAF-TVLKKAGRRGLCGTVLIHK 208
Cdd:PRK14479   80 PSADQVYAAIRAADGGA--GVLLIVGNYAGDVMNFGLAAELARAEGIDVRTVVVTDDVASaPSGETAGRRGIAGTVLVFK 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 209 VAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGS-KPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLM 287
Cdd:PRK14479  158 IAGAAAEAGLDLDEVAAIARKANARTRSMGVALDGCTLPGAgEPLFTLPEGEMELGLGIHGEPGIEREALPTADELADRL 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 288 LDHMTNttnasHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVDE 367
Cdd:PRK14479  238 VDRILA-----DLPLGAGERVAVLVNGLGATPYEELFVVYGAVARLLAARGITVVRPEVGEFVTSLDMAGASLTLMKLDD 312

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 368 PLLKLIDAETTAAAWPNVAAVSITGRkRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNALDRAAGD 447
Cdd:PRK14479  313 ELEELWDAPADTPAFRRGGAVEPVEY-VEAAEEDDAEEPPRASKASRATAANLVAALDAVAEALIDNEDELGELDAVAGD 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 448 GDCGTTHSRAARAIQEWLKEGPPP-ASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPL--KAKTSLPAWSAAMDAG 524
Cdd:PRK14479  392 GDHGIGMARGSKAALAAARAAVEAgAGAGSVLAAAGDAWADHAGGTSGPLWGTALRAAGKALgdKDEPTAADFAAAVRAA 471

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 525 LEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKSAEAAAEATKNMEAGAGRASYISSARLEQPDPG 604
Cdd:PRK14479  472 VDAIQELGGAQVGDKTMVDALVPFADALEAAAAAGADLAEAWAAAAEAAEEGAEATADLVPRMGRARYLGERSLGTPDAG 551
Dak1 pfam02733
Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.
 65-381 2.52e-146

Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.


Pssm-ID: 460667  Cd Length: 312  Bit Score: 425.71  E-value: 2.52e-146
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959  65 AGLVACNPN-LQLLQGHRVALRSDlDSLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTSPAVGSILAAIRAVA 143
Cdd:pfam02733   1 EGLAAAHPDlLRLVPGPRVVVRAD-APPKGKVALISGGGSGHEPAHAGYVGKGMLDAAVPGEVFASPSPDQILAAIKAVD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 144 QAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAF-TVLKKAGRRGLCGTVLIHKVAGALAEAGVGLEE 222
Cdd:pfam02733  80 GGA--GVLLIVKNYTGDVLNFGMAAELARAEGIKVETVVVGDDVAVgDSGGTVGRRGVAGTVLVHKIAGAAAEAGASLDE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 223 IAKQVNVVAKAMGTLGVSLSSCSVPG-SKPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLMLDHMTNTTnashvP 301
Cdd:pfam02733 158 VARLAEKVNANTRTMGVALSPCTVPGaGKPTFELGEDEMELGMGIHGEPGVKREKLKPADELVEELLDKLLDDD-----P 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 302 VQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVDEPLLKLIDAETTAAA 381
Cdd:pfam02733 233 LLPGDEVAVLVNGLGGTPLLELYIVYRRVLELLEEKGIKVVRSLVGEYMTSLDMAGFSLTLLKLDDELLELLDAPVDTPA 312
DAK1 COG2376
Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is ...
 424-604 3.72e-26

Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441943 [Multi-domain]  Cd Length: 206  Bit Score: 106.44  E-value: 3.72e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 424 LERVCSTLLGLEEHLNALDRAAGDGDCGTTHSRAARAIQEwlKEGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTA 503
Cdd:COG2376     1 MKAVADVIAENRKFLNDLDAVVGDGDHGINMARGFDAVRA--ALDAAPADPGVVLRAAGMKVASVVGGGSGGLVGTGFLD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 504 AAQPLKAKTSLPA--WSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKSAEAAAEATK 581
Cdd:COG2376    79 AAVALKGETSPTAdqVAAALRAADEGIQGRGVAYTGDKTNFDAAAPAAEAIEEAVAAGTAAAAALDEAAAAAEKGAEATR 158

                         170       180
                  ....*....|....*....|...
gi 1034572959 582 NMEAGAGRASYISSARLEQPDPG 604
Cdd:COG2376   159 SMGAALGRATYPGERSPGHPDPG 181
 
Name Accession Description Interval E-value
dak_ATP TIGR02361
dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of ...
 50-604 0e+00

dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of dihydroxyacetone kinase (also called glycerone kinase) that uses ATP (2.7.1.29) as the phosphate donor, rather than a phosphoprotein as in E. coli. This form is composed of a single chain with separable domains homologous to the K and L subunits of the E. coli enzyme, and is found in yeasts and other eukaryotes and in some bacteria, including Citrobacter freundii. The member from tomato has been shown to phosphorylate dihydroxyacetone, 3,4-dihydroxy-2-butanone, and some other aldoses and ketoses ().


Pssm-ID: 274097 [Multi-domain]  Cd Length: 574  Bit Score: 720.32  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959  50 KKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 129
Cdd:TIGR02361   1 KHFVNDPEHLVDDALKGLVAANPGLQLLESRKVVYRRDLN--KDKVSLISGGGSGHEPAHAGFVGKGMLTAAVAGDVFAS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 130 PAVGSILAAIRAVAQaGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLK--KAGRRGLCGTVLIH 207
Cdd:TIGR02361  79 PSTKQILAAIRAVVG-SEAGTLLIVKNYTGDRLNFGLAAEKAKAEGYNVEMVIVGDDVSVGRKKggLVGRRGLAGTVLVH 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 208 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGSKPTF-ELSADEVELGLGIHGEAGVRRIKMA-TADEIVK 285
Cdd:TIGR02361 158 KIAGAAAARGLSLAEVAKVAQAAADNLVTIGASLDHCHVPGETEAEpELKEDEMELGMGIHNEPGAKRISPIpSSDLVVQ 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 286 LMLDHMTNTTNA-SHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARAL-VGTFMSALEMPGISLTLL 363
Cdd:TIGR02361 238 LMLKKLLDETDKrSYVKFNEGDEVVLLVNNLGGVSNLELGIIADEVVEQLALHYNIIPVRIySGTFMTSLNGPGFSITLL 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 364 LVDE---PLLKLIDAETTAAAWPNVAAVSITGRKRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNA 440
Cdd:TIGR02361 318 NATEagkSILDLLDAPTEAPGWPVAAYSSKPWREKREVVSSSAPELIEETAVRSYDPQLVAAILESGCAALLELEPHLTK 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 441 LDRAAGDGDCGTTHSRAARAIQEWLK-EGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKAKTSLP---- 515
Cdd:TIGR02361 398 LDTKAGDGDCGSTLARGAEAILELLKsKKLPLNDPATLLAQISDVVEGVMGGTSGALYSIFFSAAAQSLKQNASKKeeit 477

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 516 --AWSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPgadllqvLTKAVKSAEAAAEATKNMEAGAGRASYI 593
Cdd:TIGR02361 478 peAWAAALKTALDALYKYTGARPGDRTMIDALQPFVEALEAGKSN-------LNAAVKAAEAGAEATKKMKAKAGRASYV 550

                         570
                  ....*....|..
gi 1034572959 594 SSARLEQ-PDPG 604
Cdd:TIGR02361 551 SSEALEGvPDPG 562
PRK14479 PRK14479
dihydroxyacetone kinase; Provisional
 50-604 3.18e-173

dihydroxyacetone kinase; Provisional


Pssm-ID: 237723 [Multi-domain]  Cd Length: 568  Bit Score: 504.35  E-value: 3.18e-173
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959  50 KKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 129
Cdd:PRK14479    2 KKLINDPSTFVEEMLEGFVAAHPDLVRLVPGGVVRRTPTP--EGKVAVVSGGGSGHEPAFAGYVGPGMLDAAVCGNVFTS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 130 PAVGSILAAIRAVAQAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAF-TVLKKAGRRGLCGTVLIHK 208
Cdd:PRK14479   80 PSADQVYAAIRAADGGA--GVLLIVGNYAGDVMNFGLAAELARAEGIDVRTVVVTDDVASaPSGETAGRRGIAGTVLVFK 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 209 VAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGS-KPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLM 287
Cdd:PRK14479  158 IAGAAAEAGLDLDEVAAIARKANARTRSMGVALDGCTLPGAgEPLFTLPEGEMELGLGIHGEPGIEREALPTADELADRL 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 288 LDHMTNttnasHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVDE 367
Cdd:PRK14479  238 VDRILA-----DLPLGAGERVAVLVNGLGATPYEELFVVYGAVARLLAARGITVVRPEVGEFVTSLDMAGASLTLMKLDD 312

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 368 PLLKLIDAETTAAAWPNVAAVSITGRkRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNALDRAAGD 447
Cdd:PRK14479  313 ELEELWDAPADTPAFRRGGAVEPVEY-VEAAEEDDAEEPPRASKASRATAANLVAALDAVAEALIDNEDELGELDAVAGD 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 448 GDCGTTHSRAARAIQEWLKEGPPP-ASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPL--KAKTSLPAWSAAMDAG 524
Cdd:PRK14479  392 GDHGIGMARGSKAALAAARAAVEAgAGAGSVLAAAGDAWADHAGGTSGPLWGTALRAAGKALgdKDEPTAADFAAAVRAA 471

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 525 LEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKSAEAAAEATKNMEAGAGRASYISSARLEQPDPG 604
Cdd:PRK14479  472 VDAIQELGGAQVGDKTMVDALVPFADALEAAAAAGADLAEAWAAAAEAAEEGAEATADLVPRMGRARYLGERSLGTPDAG 551
PTZ00375 PTZ00375
dihydroxyacetone kinase-like protein; Provisional
 49-604 4.44e-152

dihydroxyacetone kinase-like protein; Provisional


Pssm-ID: 185583 [Multi-domain]  Cd Length: 584  Bit Score: 450.80  E-value: 4.44e-152
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959  49 SKKLVNSVAGCADDALAGLVACNPN-LQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVF 127
Cdd:PTZ00375    3 SKKFINSPEKVVSEAVDGLCMTNNDsLKRIENTNVVVRSDID--KTKVLLISGGGSGHEPAHAGFVGKGWLTAAVCGSVF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 128 TSPAVGSILAAIRAVAqaGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLKKAGRRGLCGTVLIH 207
Cdd:PTZ00375   81 ASPSTKHVLAAIEYVP--NGPGCLLIVKNYTGDILNFELAVEQARARGIQVETVLVADDAAFGTKDIANRRGIAGTVLLY 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 208 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGSKPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLM 287
Cdd:PTZ00375  159 KILGAAAEKGASLTQLKKLADRISSNMRSIGVSLSSCSLPGNDPSSTVPPGTMEVGLGIHGEKGLARIPFQGAKDLVKFL 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 288 LDHMTNTTNA----SHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLL 363
Cdd:PTZ00375  239 IGILLGKGKKrgggKTTAIREGAKVALLVNNLGSTTDLEMSILAHHALRQLAQAGLTVVGVHSGRLMTSLEMHGFSLTLL 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 364 LV-DEPLLKLIDAETTAAAWPNVAAVSITGRKRSRVA--PAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNA 440
Cdd:PTZ00375  319 PIeDEDDLQLLDTNQKPLLNFHTPQSSWATAKGPLSAlqLAKPEAEAASRKAATPTNSLLRSVLERVFETLIESENYLNE 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 441 LDRAAGDGDCGTTHSRAARAIQEWLKEGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLT----AAAQPLKAKTSLPA 516
Cdd:PTZ00375  399 LDAEVGDGDLGSGLERSSKAVLESLPYLPLEANVRKTLTLISKAVADAFGGSSGPLYGAFLLgganALAEALNGGNAVDA 478

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 517 WSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKS--PGADLLQVLTKAVKSAEAAAEATKNMEAGAGRASYIS 594
Cdd:PTZ00375  479 VRAALAAGSHSIQELGGARVGDRTMVDVLIPFAEALNSCPSvnEAASSPELLKACSEEAREAAEATALLPAKHGRSRYLE 558

                         570
                  ....*....|
gi 1034572959 595 SARLEQPDPG 604
Cdd:PTZ00375  559 GKELGKKDPG 568
Dak1 pfam02733
Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.
 65-381 2.52e-146

Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.


Pssm-ID: 460667  Cd Length: 312  Bit Score: 425.71  E-value: 2.52e-146
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959  65 AGLVACNPN-LQLLQGHRVALRSDlDSLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTSPAVGSILAAIRAVA 143
Cdd:pfam02733   1 EGLAAAHPDlLRLVPGPRVVVRAD-APPKGKVALISGGGSGHEPAHAGYVGKGMLDAAVPGEVFASPSPDQILAAIKAVD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 144 QAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAF-TVLKKAGRRGLCGTVLIHKVAGALAEAGVGLEE 222
Cdd:pfam02733  80 GGA--GVLLIVKNYTGDVLNFGMAAELARAEGIKVETVVVGDDVAVgDSGGTVGRRGVAGTVLVHKIAGAAAEAGASLDE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 223 IAKQVNVVAKAMGTLGVSLSSCSVPG-SKPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLMLDHMTNTTnashvP 301
Cdd:pfam02733 158 VARLAEKVNANTRTMGVALSPCTVPGaGKPTFELGEDEMELGMGIHGEPGVKREKLKPADELVEELLDKLLDDD-----P 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 302 VQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVDEPLLKLIDAETTAAA 381
Cdd:pfam02733 233 LLPGDEVAVLVNGLGGTPLLELYIVYRRVLELLEEKGIKVVRSLVGEYMTSLDMAGFSLTLLKLDDELLELLDAPVDTPA 312
PRK14481 PRK14481
dihydroxyacetone kinase subunit DhaK; Provisional
 50-382 6.51e-122

dihydroxyacetone kinase subunit DhaK; Provisional


Pssm-ID: 237724  Cd Length: 331  Bit Score: 364.13  E-value: 6.51e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959  50 KKLVNSVAGCADDALAGLVACNPNL-QLLQGHRVALRSDLDSlkGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFT 128
Cdd:PRK14481    2 KKLINDPETVVDEMLEGLVAAHPDLvTRIDDTDVIVRKDKPP--GKVALVSGGGSGHEPAHAGFVGEGMLDAAVCGAVFT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 129 SPAVGSILAAIRAVAQAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFT-VLKKAGRRGLCGTVLIH 207
Cdd:PRK14481   80 SPTPDQILEAIKAVDTGA--GVLLIVKNYSGDVMNFEMAAELAEMEGIEVASVVVDDDVAVEdSLYTQGRRGVAGTVFVH 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 208 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGS-KPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKL 286
Cdd:PRK14481  158 KIAGAAAEAGASLDEVKALAEKVNPNIRSMGVALSPCTVPAVgKPGFDLGDDEIEIGIGIHGEPGRRREKLKPADEIAEE 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 287 MLDHMTNTtnashVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVD 366
Cdd:PRK14481  238 LLEKILED-----LKLVAGDEVLVLVNGMGATPLMELYIVYNDVAELLEERGVTVARSLVGNYMTSLDMAGFSITLLKLD 312

                         330
                  ....*....|....*.
gi 1034572959 367 EPLLKLIDAETTAAAW 382
Cdd:PRK14481  313 DELLELLDAPVDTPAL 328
dhaK1 TIGR02363
dihydroxyacetone kinase, DhaK subunit; Two types of dihydroxyacetone kinase (glycerone kinase) ...
 50-382 7.07e-116

dihydroxyacetone kinase, DhaK subunit; Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the DhaK subunit of the latter type of dihydroxyacetone kinase, but it specifically excludes the DhaK paralog DhaK2 (TIGR02362) found in the same operon as DhaK and DhaK in the Firmicutes.


Pssm-ID: 274098  Cd Length: 329  Bit Score: 348.58  E-value: 7.07e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959  50 KKLVNSVAGCADDALAGLVACNPNL-QLLQGHRVALRSDLDSlKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFT 128
Cdd:TIGR02363   2 KKLINDPEDVVAEMLDGLVKAHPELvTLVADTRVIVRKDKKV-NGKVALVSGGGSGHEPAHAGFVGYGMLDAAVPGEVFT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 129 SPAVGSILAAIRAVAQAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFT-VLKKAGRRGLCGTVLIH 207
Cdd:TIGR02363  81 SPTPDQILEAIKAVDQGA--GVLLIVKNYTGDVMNFEMAAELAEDEGIKVATVVVDDDIAVEdSLYTAGRRGVAGTVFVH 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 208 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGS-KPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKL 286
Cdd:TIGR02363 159 KIAGAAAEKGASLDELKSLGEKVNPNTKSIGVALTACTVPAVgKPGFDLADDEMEIGVGIHGEPGIRREKMKSSDEIADE 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 287 MLDHMtnttnASHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVD 366
Cdd:TIGR02363 239 LLDKL-----LDDLGLQSGDRVIVLVNGMGATPLMELYIFYNDVQRLLEQRGVNVARTLVGNYMTSLDMAGFSLTLLKLD 313

                         330
                  ....*....|....*.
gi 1034572959 367 EPLLKLIDAETTAAAW 382
Cdd:TIGR02363 314 DELLELWDAPVTTIAL 329
PRK11468 PRK11468
dihydroxyacetone kinase subunit DhaK; Provisional
 50-382 6.71e-96

dihydroxyacetone kinase subunit DhaK; Provisional


Pssm-ID: 183150  Cd Length: 356  Bit Score: 298.08  E-value: 6.71e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959  50 KKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDsLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 129
Cdd:PRK11468    2 KKLINDVEDVLDEQLAGLAKAHPELTLHQDPVYVTRADAP-VAGKVALLSGGGSGHEPMHCGFVGQGMLDGACPGEIFTS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 130 PAVGSILAAIRAVaqAGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFT-VLKKAGRRGLCGTVLIHK 208
Cdd:PRK11468   81 PTPDQMFECAMQV--DGGEGVLLIIKNYTGDVLNFETATELLHDSGVKVTTVLIDDDVAVKdSLYTAGRRGVANTVLIEK 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 209 VAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGS-KPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLM 287
Cdd:PRK11468  159 LVGAAAERGYSLDQCAELGRKLNNQGHSIGIALGACTVPAAgKPSFTLADNEMEFGVGIHGEPGIDRRPFSSLDQTVDEM 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 288 LDHMTNTTNASHV-------------------PVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGT 348
Cdd:PRK11468  239 FDTLLENGSYHRTlrfwdrqqgswqeeeqtkqPLQSGDRVIALVNNLGATPLSELYGVYNRLATRCEQAGLTIERNLIGA 318

                         330       340       350
                  ....*....|....*....|....*....|....
gi 1034572959 349 FMSALEMPGISLTLLLVDEPLLKLIDAETTAAAW 382
Cdd:PRK11468  319 YCTSLDMQGFSITLLKVDDETLALWDAPVHTPAL 352
PRK14483 PRK14483
DhaKLM operon coactivator DhaQ; Provisional
 50-382 2.90e-79

DhaKLM operon coactivator DhaQ; Provisional


Pssm-ID: 172956  Cd Length: 329  Bit Score: 253.82  E-value: 2.90e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959  50 KKLVNSVAGCADDALAGLVACNPNLQllQGHRVALRSDLDSLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 129
Cdd:PRK14483    2 KKIMNDVQNIVQDMLHGFYFAHPNLD--ETNNIPYVYDIEKDDQLVPIISGGGSGHEPAHIGYVGKGMLTAAVNGSIFTP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 130 PAVGSILAAIRAVAQAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLK--KAGRRGLCGTVLIH 207
Cdd:PRK14483   80 PTAEQILAATRLVPKGK--GVFFIIKNFEADVAEFSAAIQIARQEGRQIKYIIVHDDISVEDDAsfNKRRRGVAGTVLLH 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 208 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPG-SKPTFELSADEVELGLGIHGEAGVRRIKMAT----ADE 282
Cdd:PRK14483  158 KILGAAALEGASLDELEQLGLSLTENIATLGVALSPANLPVaGLPSFDLNEDEISYGIGIHGEPGYRKEPFSSseilAIE 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 283 IV-KLmldhmtnttnASHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLT 361
Cdd:PRK14483  238 LVnKL----------KSKYRWQKGDNFILLINGLGATTLMEQYIFANDIRRLLELEGLQITFVKVGTLLTSLDMKGISLT 307

                         330       340
                  ....*....|....*....|..
gi 1034572959 362 LLLV-DEPLLKLIDAETTAAAW 382
Cdd:PRK14483  308 LLKVkDPDWLDWLKAPTRAAAW 329
dhaK1b TIGR02362
probable dihydroxyacetone kinase DhaK1b subunit; Two types of dihydroxyacetone kinase ...
 51-382 7.13e-68

probable dihydroxyacetone kinase DhaK1b subunit; Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form with a phosphoprotein donor related to PTS transport proteins. This family represents a protein, unique to the Firmicutes (low GC Gram-positives), that appears to be a divergent second copy of the K subunit of that complex; its gene is always found in operons with the other three proteins of the complex.


Pssm-ID: 213706  Cd Length: 326  Bit Score: 223.91  E-value: 7.13e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959  51 KLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTSP 130
Cdd:TIGR02362   1 KIINEPQNAVSQAIQGIQWAYPNLVQVPDLPGIYDSNFD--DQQIPIISGGGSGHEPAHWGYVGEGMLSAAIMGDVFVPP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 131 AVGSILAAIRAVAQAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDD-SAFTVLKKAGRRGLCGTVLIHKV 209
Cdd:TIGR02362  79 TAQDILEAIRQVDRGK--GVFVIIKNFEADLSEFSQAIQQARQEGRQIKYIIVHDDiSVEHESFKQRRRGVAGTILVHKI 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 210 AGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPG-SKPTFELSADEVELGLGIHGEAGVRRIKMAT----ADEIV 284
Cdd:TIGR02362 157 LGAAAAEGASLDELEHIAAALVTNIATIGVAAKSARIPGqSTPSFDLEEGEIYYGIGIHGEPGYRTEPFVSsehlAVELV 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 285 -KLMLDHMTnttnashvpvQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLL 363
Cdd:TIGR02362 237 nKLKLKFRW----------QADDHYAVLVNNLGGTTPMEQMVFNNDVHELLALEALHLPFIKVGTFLTSLDMHGLSLTLL 306

                         330       340
                  ....*....|....*....|
gi 1034572959 364 -LVDEPLLKLIDAETTAAAW 382
Cdd:TIGR02362 307 rLKDPQWLDYLNAPVDAAAW 326
Dak2 pfam02734
DAK2 domain; This domain is the predicted phosphatase domain of the dihydroxyacetone kinase ...
 444-604 2.17e-44

DAK2 domain; This domain is the predicted phosphatase domain of the dihydroxyacetone kinase family.


Pssm-ID: 460668 [Multi-domain]  Cd Length: 175  Bit Score: 156.19  E-value: 2.17e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 444 AAGDGDCGTTHSRAARAIQEWLKEGPPpASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKAKTSL--PAWSAAM 521
Cdd:pfam02734   1 PVGDGDHGTNMARGFEAALKALEDLEP-ASLAEVLKALAMALLSGAGGNSGPLYGQFFRGAAKALKGKEELdaEDLAAAL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 522 DAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKSAEAAAEATKNMEAGAGRASYISSARLEQP 601
Cdd:pfam02734  80 EAALEAIQARGKARPGDKTMLDVLRPAAEALEAAAEAGEDLAEALEAAVKAAEEGAEATKELLAKLGRASYLGERSIGVV 159


                  ...
gi 1034572959 602 DPG 604
Cdd:pfam02734 160 DPG 162
DAK1 COG2376
Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is ...
 424-604 3.72e-26

Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441943 [Multi-domain]  Cd Length: 206  Bit Score: 106.44  E-value: 3.72e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 424 LERVCSTLLGLEEHLNALDRAAGDGDCGTTHSRAARAIQEwlKEGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTA 503
Cdd:COG2376     1 MKAVADVIAENRKFLNDLDAVVGDGDHGINMARGFDAVRA--ALDAAPADPGVVLRAAGMKVASVVGGGSGGLVGTGFLD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 504 AAQPLKAKTSLPA--WSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKSAEAAAEATK 581
Cdd:COG2376    79 AAVALKGETSPTAdqVAAALRAADEGIQGRGVAYTGDKTNFDAAAPAAEAIEEAVAAGTAAAAALDEAAAAAEKGAEATR 158

                         170       180
                  ....*....|....*....|...
gi 1034572959 582 NMEAGAGRASYISSARLEQPDPG 604
Cdd:COG2376   159 SMGAALGRATYPGERSPGHPDPG 181
dha_L_ycgS TIGR02365
dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Two types of dihydroxyacetone ...
 424-604 9.54e-26

dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the subunit homologous to the E. coli YcgS subunit.


Pssm-ID: 274099 [Multi-domain]  Cd Length: 194  Bit Score: 104.74  E-value: 9.54e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 424 LERVCSTLLGLEEHLNALDRAAGDGDCGTTHSRAARAIQEWLKEgPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTA 503
Cdd:TIGR02365   5 LKNCGDLIIENKEYLTELDRAIGDGDHGINMARGFSEVKEKLDA-FKDKTIGEILKNTGMTLISKVGGASGPLYGTAFLK 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 504 AAQPLKAKTSLPAWSAA--MDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAwkspGADLLQVLTKAVKSAEAAAEATK 581
Cdd:TIGR02365  84 ASKALKDDEILDAEDLAeiLQAGLEGIQSRGKATPGEKTMVDVWAPVVEALRK----AADEPDALAAAREAAEQGAEATK 159

                         170       180
                  ....*....|....*....|...
gi 1034572959 582 NMEAGAGRASYISSARLEQPDPG 604
Cdd:TIGR02365 160 DMQATKGRASYLGERSIGHIDPG 182
PRK10005 PRK10005
dihydroxyacetone kinase ADP-binding subunit DhaL;
424-604 4.26e-21

dihydroxyacetone kinase ADP-binding subunit DhaL;


Pssm-ID: 182192 [Multi-domain]  Cd Length: 210  Bit Score: 91.72  E-value: 4.26e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 424 LERVCSTLLGLEEHLNALDRAAGDGDCGTTHSRAARAIQEWLkegPPPASP--AQLLSKLSVLLLEKMGGSSGALYGLFL 501
Cdd:PRK10005   12 LTRCGDIFTEESDYLTGLDREIGDADHGLNMNRGFSKVVEKL---PAIADKdiGFILKNTGMTLLSSVGGASGPLYGTFF 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 502 TAAAQPLKAKTSLPA--WSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKSAEAAAEA 579
Cdd:PRK10005   89 IRAAQATQARQSLTLeeLYQMFRDGADGVISRGKAEPGDKTMCDVWVPVVESLRQSSEQNLSVPAALNAAVSIAESAAQS 168

                         170       180
                  ....*....|....*....|....*
gi 1034572959 580 TKNMEAGAGRASYISSARLEQPDPG 604
Cdd:PRK10005  169 TITMQARKGRASYLGERSIGHQDPG 193
DAK1 COG2376
Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is ...
 50-248 3.89e-13

Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441943 [Multi-domain]  Cd Length: 206  Bit Score: 68.69  E-value: 3.89e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959  50 KKLVNSVAGCADDALAGLVACNPN---LQLLQGHRVALRSDLDSLKGRVALLSGGGSGhepahaGFIGKGMLTGVIAGAV 126
Cdd:COG2376    12 RKFLNDLDAVVGDGDHGINMARGFdavRAALDAAPADPGVVLRAAGMKVASVVGGGSG------GLVGTGFLDAAVALKG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034572959 127 FTSPAVGSILAAIRAVAQA-GTVGtllivKNYTGDRLNFGLAREQARAegipVEMVVIGDDSAftvlkkagrrglcgtvl 205
Cdd:COG2376    86 ETSPTADQVAAALRAADEGiQGRG-----VAYTGDKTNFDAAAPAAEA----IEEAVAAGTAA----------------- 139

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1034572959 206 ihkvAGALAEAgvglEEIAKQvnvVAKAMGTLGVSLSSCSVPG 248
Cdd:COG2376   140 ----AAALDEA----AAAAEK---GAEATRSMGAALGRATYPG 171
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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