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Conserved domains on  [gi|1034559575|ref|XP_016857076|]
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sushi domain-containing protein 4 isoform X4 [Homo sapiens]

Protein Classification

beta-2-glycoprotein 1( domain architecture ID 13269567)

beta-2-glycoprotein 1 is a heavily glycosylated plasma membrane-adhesion protein, which plays a role in blood coagulation and removal of apoptotic bodies

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02639 super family cl31493
EEV host range protein; Provisional
 30-238 1.31e-13

EEV host range protein; Provisional


The actual alignment was detected with superfamily member PHA02639:

Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 71.23  E-value: 1.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575  30 LAVILWFQLALCFgpaqlTGGFDDLqVCADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLgW 109
Cdd:PHA02639    1 MKIILYLFIGVCY-----VHGVKSI-YCDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAI-W 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575 110 iPSDNSICVQEDCR-IPQIEDAEIHNK--TYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDGTWN-NLPICQ--GCLRP 183
Cdd:PHA02639   74 -SNKAPFCMLKECNdPPSIINGKIYNKreMYKVGDEIYYVCNEHKGVQYSLVGNEKITCIQDKSWKpDPPICKmiNCRFP 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1034559575 184 lASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRCL 238
Cdd:PHA02639  153 -ALQNGYINGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTCV 206
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 243-297 3.49e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


:

Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.83  E-value: 3.49e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034559575  243 CPLPPMVSHGDFVCHPRPcerYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEWFPS 297
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT---YSYGDTVTYSCDPGYTLIGS-STITCLeNGTWSPP 52
 
Name Accession Description Interval E-value
PHA02639 PHA02639
EEV host range protein; Provisional
 30-238 1.31e-13

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 71.23  E-value: 1.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575  30 LAVILWFQLALCFgpaqlTGGFDDLqVCADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLgW 109
Cdd:PHA02639    1 MKIILYLFIGVCY-----VHGVKSI-YCDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAI-W 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575 110 iPSDNSICVQEDCR-IPQIEDAEIHNK--TYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDGTWN-NLPICQ--GCLRP 183
Cdd:PHA02639   74 -SNKAPFCMLKECNdPPSIINGKIYNKreMYKVGDEIYYVCNEHKGVQYSLVGNEKITCIQDKSWKpDPPICKmiNCRFP 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1034559575 184 lASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRCL 238
Cdd:PHA02639  153 -ALQNGYINGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTCV 206
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 180-237 9.23e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.17  E-value: 9.23e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1034559575 180 CLRPLASSNGYVNISelQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Cdd:cd00033     1 CPPPPVPENGTVTGS--KGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 180-237 1.73e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 56.38  E-value: 1.73e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1034559575  180 CLRPLASSNGYVNISelQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Cdd:smart00032   1 CPPPPDIENGTVTSS--SGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
190-237 3.93e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 52.50  E-value: 3.93e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1034559575 190 YVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Cdd:pfam00084   9 NGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 243-297 3.49e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.83  E-value: 3.49e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034559575  243 CPLPPMVSHGDFVCHPRPcerYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEWFPS 297
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT---YSYGDTVTYSCDPGYTLIGS-STITCLeNGTWSPP 52
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 243-294 7.50e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.00  E-value: 7.50e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1034559575 243 CPLPPMVSHGDFVCHPrpcERYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEW 294
Cdd:cd00033     1 CPPPPVPENGTVTGSK---GSYSYGSTVTYSCNEGYTLVGS-STITCTeNGGW 49
Sushi pfam00084
Sushi repeat (SCR repeat);
243-294 5.50e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 43.64  E-value: 5.50e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1034559575 243 CPLPPMVSHGDFVChprPCERYNHGTVVEFYCDPGYSLTSDYKyITCQ-YGEW 294
Cdd:pfam00084   1 CPPPPDIPNGKVSA---TKNEYNYGASVSYECDPGYRLVGSPT-ITCQeDGTW 49
 
Name Accession Description Interval E-value
PHA02639 PHA02639
EEV host range protein; Provisional
 30-238 1.31e-13

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 71.23  E-value: 1.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575  30 LAVILWFQLALCFgpaqlTGGFDDLqVCADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLgW 109
Cdd:PHA02639    1 MKIILYLFIGVCY-----VHGVKSI-YCDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAI-W 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575 110 iPSDNSICVQEDCR-IPQIEDAEIHNK--TYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDGTWN-NLPICQ--GCLRP 183
Cdd:PHA02639   74 -SNKAPFCMLKECNdPPSIINGKIYNKreMYKVGDEIYYVCNEHKGVQYSLVGNEKITCIQDKSWKpDPPICKmiNCRFP 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1034559575 184 lASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRCL 238
Cdd:PHA02639  153 -ALQNGYINGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTCV 206
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 57-238 1.40e-12

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 67.76  E-value: 1.40e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575  57 CADPGIPENGfRTPSGGVFFeGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPsDNSICVQEDCRIPQIEDAEIHN-- 134
Cdd:PHA02927   86 CPSPRDIDNG-QLDIGGVDF-GSSITYSCNSGYQLIGESKSYCELGSTGSMVWNP-EAPICESVKCQSPPSISNGRHNgy 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575 135 -KTYRHGEKLIITCHEGFKIrypdLHNMVSLCrDDGTWNNLPICQ--GCLRPlASSNGYVNiSELQTSFPVGTVISYRCF 211
Cdd:PHA02927  163 eDFYTDGSVVTYSCNSGYSL----IGNSGVLC-SGGEWSDPPTCQivKCPHP-TISNGYLS-SGFKRSYSYNDNVDFKCK 235

                         170       180
                  ....*....|....*....|....*..
gi 1034559575 212 PGFKLDGSAYLECLQNLIWSSSPPRCL 238
Cdd:PHA02927  236 YGYKLSGSSSSTCSPGNTWQPELPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 180-237 9.23e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.17  E-value: 9.23e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1034559575 180 CLRPLASSNGYVNISelQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Cdd:cd00033     1 CPPPPVPENGTVTGS--KGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 180-237 1.73e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 56.38  E-value: 1.73e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1034559575  180 CLRPLASSNGYVNISelQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Cdd:smart00032   1 CPPPPDIENGTVTSS--SGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 134-294 5.02e-10

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 60.05  E-value: 5.02e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575 134 NKTYRHGEKLIITCHEGFkiRYPDLHNMVSLCRDDG-TWNNLPICQGCLRPLASSNGYVNISELQtsfpVGTVISYRCFP 212
Cdd:PHA02927   41 NANYNIGDTIEYLCLPGY--RKQKMGPIYAKCTGTGwTLFNQCIKRRCPSPRDIDNGQLDIGGVD----FGSSITYSCNS 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575 213 GFKLDGSAYLEC----LQNLIWSSSPPRCLALEvCPLPPMVSHGDfvcHPRPCERYNHGTVVEFYCDPGYSLTSDYKyIT 288
Cdd:PHA02927  115 GYQLIGESKSYCelgsTGSMVWNPEAPICESVK-CQSPPSISNGR---HNGYEDFYTDGSVVTYSCNSGYSLIGNSG-VL 189


                  ....*.
gi 1034559575 289 CQYGEW 294
Cdd:PHA02927  190 CSGGEW 195
PHA02817 PHA02817
EEV Host range protein; Provisional
 115-237 2.00e-09

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 57.64  E-value: 2.00e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575 115 SICVQEDCRIP-QIEDAEIHNK--TYRHGEKLIITCHEGFK-IRYPDLHNMVSLCRDDGTWN-NLPICQ--GCLRPlASS 187
Cdd:PHA02817   17 SLCDLNKCCYPpSIKNGYIYNKktEYNIGSNVTFFCGNNTRgVRYTLVGEKNIICEKDGKWNkEFPVCKiiRCRFP-ALQ 95

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1034559575 188 NGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Cdd:PHA02817   96 NGFVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPIC 145
Sushi pfam00084
Sushi repeat (SCR repeat);
190-237 3.93e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 52.50  E-value: 3.93e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1034559575 190 YVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Cdd:pfam00084   9 NGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 243-297 3.49e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.83  E-value: 3.49e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034559575  243 CPLPPMVSHGDFVCHPRPcerYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEWFPS 297
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT---YSYGDTVTYSCDPGYTLIGS-STITCLeNGTWSPP 52
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 243-294 7.50e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.00  E-value: 7.50e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1034559575 243 CPLPPMVSHGDFVCHPrpcERYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEW 294
Cdd:cd00033     1 CPPPPVPENGTVTGSK---GSYSYGSTVTYSCNEGYTLVGS-STITCTeNGGW 49
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 57-102 1.50e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 48.23  E-value: 1.50e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1034559575  57 CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKH 102
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN 46
PHA02639 PHA02639
EEV host range protein; Provisional
 180-296 7.39e-07

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 50.82  E-value: 7.39e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575 180 CLRPLASSNGYvnISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQ---NLIWSSSPPRCLaLEVCPLPPMVSHGDfVC 256
Cdd:PHA02639   22 CDKPDDISNGF--ITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKdknNAIWSNKAPFCM-LKECNDPPSIINGK-IY 97

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1034559575 257 HPRpcERYNHGTVVEFYCDP----GYSLTSDYKYITCQYGEWFP 296
Cdd:PHA02639   98 NKR--EMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIQDKSWKP 139
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 57-100 9.68e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 45.60  E-value: 9.68e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1034559575   57 CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCL 100
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCL 44
PHA02831 PHA02831
EEV host range protein; Provisional
 104-238 1.16e-06

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 49.99  E-value: 1.16e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575 104 NGTlgWipSDNSICV-QEDCRIP-QIEDAEIHNKT--YRHGEKLIITCHEGFKIRYPDLHNMVSLCRDdGTW-NNLPICQ 178
Cdd:PHA02831   63 NGS--W--STKNMCIgKRNCKDPvTILNGYIKNKKdqYSFGDSVTYACKVNKLEKYSIVGNETVKCIN-KQWvPKYPVCK 137

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034559575 179 --GCLRPlASSNGYVNIseLQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRCL 238
Cdd:PHA02831  138 liRCKYP-ALQNGFLNV--FEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCV 196
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 54-296 4.06e-06

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 48.50  E-value: 4.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575  54 LQVCADPGIP-----ENGFRTPSGGVFFEGSVARFHCQDGFKLK--GATKRLClkhfNGTlGWIPSDNsiCVQEDCRIPQ 126
Cdd:PHA02927   18 LSCCTIPSRPinmkfKNSVETDANANYNIGDTIEYLCLPGYRKQkmGPIYAKC----TGT-GWTLFNQ--CIKRRCPSPR 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575 127 -IEDAEIHNKTYRHGEKLIITCHEGFKIrypdLHNMVSLCRDDGT----WN-NLPICQG--CLRPLASSNGYVNISElqT 198
Cdd:PHA02927   91 dIDNGQLDIGGVDFGSSITYSCNSGYQL----IGESKSYCELGSTgsmvWNpEAPICESvkCQSPPSISNGRHNGYE--D 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575 199 SFPVGTVISYRCFPGFKLDGSAYLEClQNLIWSSsPPRCLALEvCPlPPMVSHGDFVCHPRpcERYNHGTVVEFYCDPGY 278
Cdd:PHA02927  165 FYTDGSVVTYSCNSGYSLIGNSGVLC-SGGEWSD-PPTCQIVK-CP-HPTISNGYLSSGFK--RSYSYNDNVDFKCKYGY 238

                         250
                  ....*....|....*....
gi 1034559575 279 SLTSDYKYiTCQYGE-WFP 296
Cdd:PHA02927  239 KLSGSSSS-TCSPGNtWQP 256
Sushi pfam00084
Sushi repeat (SCR repeat);
243-294 5.50e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 43.64  E-value: 5.50e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1034559575 243 CPLPPMVSHGDFVChprPCERYNHGTVVEFYCDPGYSLTSDYKyITCQ-YGEW 294
Cdd:pfam00084   1 CPPPPDIPNGKVSA---TKNEYNYGASVSYECDPGYRLVGSPT-ITCQeDGTW 49
Sushi pfam00084
Sushi repeat (SCR repeat);
57-104 5.77e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 43.64  E-value: 5.77e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1034559575  57 CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFN 104
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGT 48
PHA02831 PHA02831
EEV host range protein; Provisional
 115-304 9.17e-06

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 47.29  E-value: 9.17e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575 115 SICV--QEDCRIPQIEDAEihNKTYRHGEKLIITCHEGFkirypdlhNMVSLCRDDGTWNNLPICQG---CLRPLASSNG 189
Cdd:PHA02831   18 CICVfnKNDAKYSNVDSYE--NKVYEENENLEYKCNNNF--------DKVFVTCNNGSWSTKNMCIGkrnCKDPVTILNG 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575 190 YVNISELQTSFpvGTVISYRC----FPGFKLDGSAYLECLqNLIWSSSPPRClALEVCPLPPMvSHGDFVCHPRpceRYN 265
Cdd:PHA02831   88 YIKNKKDQYSF--GDSVTYACkvnkLEKYSIVGNETVKCI-NKQWVPKYPVC-KLIRCKYPAL-QNGFLNVFEK---KFY 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1034559575 266 HGTVVEFYCDPGY----SLTSdykyiTCQYGE-WFPSYQvYCIK 304
Cdd:PHA02831  160 YGDIVNFKCKKGFillgSSVS-----TCDINSiWYPGIP-KCVK 197
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 92-238 1.52e-05

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 47.00  E-value: 1.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575  92 KGATKRLCLKHFNGTLGWipSDNSICVQEDCRIPQIEDAEIH--NKTYRHGEKLIITCHEGFKIRYPDLHNMVSlcrddG 169
Cdd:PHA02954  102 KDETKYFRCEEKNGNTSW--NDTVTCPNAECQPLQLEHGSCQpvKEKYSFGEHITINCDVGYEVIGASYISCTA-----N 174

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034559575 170 TWNNLPICQGCLRPLASSNGYVNISelqtSFPVGTVISYRCFPGFKLDGSAYLECLQNLiWSSSPPRCL 238
Cdd:PHA02954  175 SWNVIPSCQQKCDIPSLSNGLISGS----TFSIGGVIHLSCKSGFTLTGSPSSTCIDGK-WNPVLPICV 238
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 125-177 1.53e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 36.74  E-value: 1.53e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034559575  125 PQIEDAEI--HNKTYRHGEKLIITCHEGFKIRYPDlhnmVSLCRDDGTWNN-LPIC 177
Cdd:smart00032   5 PDIENGTVtsSSGTYSYGDTVTYSCDPGYTLIGSS----TITCLENGTWSPpPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 125-178 7.24e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 34.75  E-value: 7.24e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034559575 125 PQIEDAEI--HNKTYRHGEKLIITCHEGFKIRYPDlhnmVSLCRDDGTWNN-LPICQ 178
Cdd:cd00033     5 PVPENGTVtgSKGSYSYGSTVTYSCNEGYTLVGSS----TITCTENGGWSPpPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
122-177 9.08e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 34.40  E-value: 9.08e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559575 122 CRIPQ-IEDAEIH--NKTYRHGEKLIITCHEGFkiRYPDlhNMVSLCRDDGTWNNL-PIC 177
Cdd:pfam00084   1 CPPPPdIPNGKVSatKNEYNYGASVSYECDPGY--RLVG--SPTITCQEDGTWSPPfPEC 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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