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Conserved domains on  [gi|2024366606|ref|XP_015151570|]
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LOW QUALITY PROTEIN: seizure protein 6 homolog isoform X1 [Gallus gallus]

Protein Classification

CUB domain-containing protein( domain architecture ID 12869279)

CUB (complement C1r/C1s, Uegf, Bmp1) domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 380-490 4.46e-23

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 95.17  E-value: 4.46e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 380 CGGAIRNATVGRVVSPGFPGNYSNNLTCHWLLEAPVGHRLHLHFEKVSLAEDD----DRLIIRNGNNVEApPVYDSYEVE 455
Cdd:cd00041     1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPncsyDYLEIYDGPSTSS-PLLGRFCGS 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2024366606 456 YLPIEgLLSTGRHFFVELTTDSSGAAAGMALRYEA 490
Cdd:cd00041    80 TLPPP-IISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 557-666 4.90e-20

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 86.31  E-value: 4.90e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 557 CSGELMDTA-GVVLSPNWPEAYGKGQDCIWGLHVEEDKRVMLDIRVLRLGAG-----DVLTFYDGDDLTARILGQYTGAR 630
Cdd:cd00041     1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2024366606 631 GRFKLFASSADVTIQFQSDPGAGvfayRQGFVIHFS 666
Cdd:cd00041    81 LPPPIISSGNSLTVRFRSDSSVT----GRGFKATYS 112
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 674-859 5.99e-13

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 70.07  E-value: 5.99e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 674 CPELPDIANGWKTASQPELlhGTVVTFHCYPGFELAGADLLMCHW----DLTWSGDLPSCERVTtCRDPGDAEHSRRVVS 749
Cdd:PHA02927   86 CPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESVK-CQSPPSISNGRHNGY 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 750 SPKFPVGSTVRFVCDKGYVLAGAGLLTChdraSGGpKWSDRlPKCipeAYEPCHNPGVPAGGRQSPERRLYPAGSTLRFS 829
Cdd:PHA02927  163 EDFYTDGSVVTYSCNSGYSLIGNSGVLC----SGG-EWSDP-PTC---QIVKCPHPTISNGYLSSGFKRSYSYNDNVDFK 233

                         170       180       190
                  ....*....|....*....|....*....|
gi 2024366606 830 CTAGRALLGEGNLRCLPGHPsrWSGSPPIC 859
Cdd:PHA02927  234 CKYGYKLSGSSSSTCSPGNT--WQPELPKC 261
Sushi pfam00084
Sushi repeat (SCR repeat);
496-553 8.11e-11

Sushi repeat (SCR repeat);


:

Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 58.28  E-value: 8.11e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024366606 496 CYEPF-VKYGNFTTSDPRYPVGTTVEFSCHPGYTLeQGSTIIECVDpsDPQWNETEPAC 553
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRL-VGSPTITCQE--DGTWSPPFPEC 56
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 209-316 1.42e-09

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 56.65  E-value: 1.42e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 209 CNRTL-AGPEGWLVSPEPaSAPYDSSMDCTYTISVYPGYGVEIKVQNISLADGET-----LTVESAGGLEPAVLANESFL 282
Cdd:cd00041     1 CGGTLtASTSGTISSPNY-PNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPNcsydyLEIYDGPSTSSPLLGRFCGS 79

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2024366606 283 LRGQVIRSPANVLTLRFQSPRSTSPGSYRFQYQA 316
Cdd:cd00041    80 TLPPPIISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 321-376 1.60e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 43.22  E-value: 1.60e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2024366606 321 CPFPARPAFGDVSVS--SLHPGGDARFRCTTGYQLQGAHLITCRNATRpfWSAREPQC 376
Cdd:cd00033     1 CPPPPVPENGTVTGSkgSYSYGSTVTYSCNEGYTLVGSSTITCTENGG--WSPPPPTC 56
 
Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 380-490 4.46e-23

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 95.17  E-value: 4.46e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 380 CGGAIRNATVGRVVSPGFPGNYSNNLTCHWLLEAPVGHRLHLHFEKVSLAEDD----DRLIIRNGNNVEApPVYDSYEVE 455
Cdd:cd00041     1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPncsyDYLEIYDGPSTSS-PLLGRFCGS 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2024366606 456 YLPIEgLLSTGRHFFVELTTDSSGAAAGMALRYEA 490
Cdd:cd00041    80 TLPPP-IISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 557-666 4.90e-20

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 86.31  E-value: 4.90e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 557 CSGELMDTA-GVVLSPNWPEAYGKGQDCIWGLHVEEDKRVMLDIRVLRLGAG-----DVLTFYDGDDLTARILGQYTGAR 630
Cdd:cd00041     1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2024366606 631 GRFKLFASSADVTIQFQSDPGAGvfayRQGFVIHFS 666
Cdd:cd00041    81 LPPPIISSGNSLTVRFRSDSSVT----GRGFKATYS 112
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 390-488 8.30e-19

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 82.44  E-value: 8.30e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606  390 GRVVSPGFPGNYSNNLTCHWLLEAPVGHRLHLHFEKVSLAEDD----DRLIIRNGNNVEApPVYDSYEVEYLPIEGLLST 465
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSDnceyDYVEIYDGPSASS-PLLGRFCGSEAPPPVISSS 79

                           90       100
                   ....*....|....*....|...
gi 2024366606  466 GRHFFVELTTDSSGAAAGMALRY 488
Cdd:smart00042  80 SNSLTLTFVSDSSVQKRGFSARY 102
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 566-665 1.60e-15

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 73.19  E-value: 1.60e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606  566 GVVLSPNWPEAYGKGQDCIWGLHVEEDKRVMLDIRVLRLGAG-----DVLTFYDGDDLTARILGQYTGARGRFKLFAS-S 639
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSdnceyDYVEIYDGPSASSPLLGRFCGSEAPPPVISSsS 80

                           90       100
                   ....*....|....*....|....*.
gi 2024366606  640 ADVTIQFQSDPGAGvfayRQGFVIHF 665
Cdd:smart00042  81 NSLTLTFVSDSSVQ----KRGFSARY 102
CUB pfam00431
CUB domain;
380-488 2.29e-14

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 70.02  E-value: 2.29e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 380 CGGAIRNATvGRVVSPGFPGNYSNNLTCHWLLEAPVGHRLHLHFEKVSLAEDD----DRLIIRNGNNvEAPPVYDSYEVE 455
Cdd:pfam00431   1 CGGVLTDSS-GSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHDecgyDYVEIRDGPS-ASSPLLGRFCGS 78

                          90       100       110
                  ....*....|....*....|....*....|...
gi 2024366606 456 YLPiEGLLSTGRHFFVELTTDSSGAAAGMALRY 488
Cdd:pfam00431  79 GIP-EDIVSSSNQMTIKFVSDASVQKRGFKATY 110
CUB pfam00431
CUB domain;
557-665 3.42e-14

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 69.63  E-value: 3.42e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 557 CSGELMDTAGVVLSPNWPEAYGKGQDCIWGLHVEEDKRVML-----DIRVLRLGAGDVLTFYDGDDLTARILGQYTGARG 631
Cdd:pfam00431   1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLtfqdfELEDHDECGYDYVEIRDGPSASSPLLGRFCGSGI 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2024366606 632 RFKLFASSADVTIQFQSDPGagvfAYRQGFVIHF 665
Cdd:pfam00431  81 PEDIVSSSNQMTIKFVSDAS----VQKRGFKATY 110
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 674-859 5.99e-13

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 70.07  E-value: 5.99e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 674 CPELPDIANGWKTASQPELlhGTVVTFHCYPGFELAGADLLMCHW----DLTWSGDLPSCERVTtCRDPGDAEHSRRVVS 749
Cdd:PHA02927   86 CPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESVK-CQSPPSISNGRHNGY 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 750 SPKFPVGSTVRFVCDKGYVLAGAGLLTChdraSGGpKWSDRlPKCipeAYEPCHNPGVPAGGRQSPERRLYPAGSTLRFS 829
Cdd:PHA02927  163 EDFYTDGSVVTYSCNSGYSLIGNSGVLC----SGG-EWSDP-PTC---QIVKCPHPTISNGYLSSGFKRSYSYNDNVDFK 233

                         170       180       190
                  ....*....|....*....|....*....|
gi 2024366606 830 CTAGRALLGEGNLRCLPGHPsrWSGSPPIC 859
Cdd:PHA02927  234 CKYGYKLSGSSSSTCSPGNT--WQPELPKC 261
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 674-730 1.33e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 63.25  E-value: 1.33e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2024366606 674 CPELPDIANGWKTASQPELLHGTVVTFHCYPGFELAGADLLMCHWDLTWSGDLPSCE 730
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 674-729 1.31e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 60.23  E-value: 1.31e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024366606  674 CPELPDIANGWKTASQPELLHGTVVTFHCYPGFELAGADLLMCHWDLTWSGDLPSC 729
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
496-553 8.11e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 58.28  E-value: 8.11e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024366606 496 CYEPF-VKYGNFTTSDPRYPVGTTVEFSCHPGYTLeQGSTIIECVDpsDPQWNETEPAC 553
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRL-VGSPTITCQE--DGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 499-554 2.34e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.70  E-value: 2.34e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024366606 499 PFVKYGNFTTSDPRYPVGTTVEFSCHPGYTLeQGSTIIECVdpSDPQWNETEPACR 554
Cdd:cd00033     5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTL-VGSSTITCT--ENGGWSPPPPTCE 57
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 209-316 1.42e-09

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 56.65  E-value: 1.42e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 209 CNRTL-AGPEGWLVSPEPaSAPYDSSMDCTYTISVYPGYGVEIKVQNISLADGET-----LTVESAGGLEPAVLANESFL 282
Cdd:cd00041     1 CGGTLtASTSGTISSPNY-PNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPNcsydyLEIYDGPSTSSPLLGRFCGS 79

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2024366606 283 LRGQVIRSPANVLTLRFQSPRSTSPGSYRFQYQA 316
Cdd:cd00041    80 TLPPPIISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 499-553 1.43e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 54.45  E-value: 1.43e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024366606  499 PFVKYGNFTTSDPRYPVGTTVEFSCHPGYTLeQGSTIIECVDpsDPQWNETEPAC 553
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTL-IGSSTITCLE--NGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
674-729 4.06e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 53.27  E-value: 4.06e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024366606 674 CPELPDIANGWKTASQPELLHGTVVTFHCYPGFELAGADLLMCHWDLTWSGDLPSC 729
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 321-376 1.60e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 43.22  E-value: 1.60e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2024366606 321 CPFPARPAFGDVSVS--SLHPGGDARFRCTTGYQLQGAHLITCRNATRpfWSAREPQC 376
Cdd:cd00033     1 CPPPPVPENGTVTGSkgSYSYGSTVTYSCNEGYTLVGSSTITCTENGG--WSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 321-376 2.00e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.90  E-value: 2.00e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2024366606  321 CPFPARPAFGDVSVSS--LHPGGDARFRCTTGYQLQGAHLITCRNATRpfWSAREPQC 376
Cdd:smart00032   1 CPPPPDIENGTVTSSSgtYSYGDTVTYSCDPGYTLIGSSTITCLENGT--WSPPPPTC 56
 
Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 380-490 4.46e-23

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 95.17  E-value: 4.46e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 380 CGGAIRNATVGRVVSPGFPGNYSNNLTCHWLLEAPVGHRLHLHFEKVSLAEDD----DRLIIRNGNNVEApPVYDSYEVE 455
Cdd:cd00041     1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPncsyDYLEIYDGPSTSS-PLLGRFCGS 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2024366606 456 YLPIEgLLSTGRHFFVELTTDSSGAAAGMALRYEA 490
Cdd:cd00041    80 TLPPP-IISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 557-666 4.90e-20

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 86.31  E-value: 4.90e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 557 CSGELMDTA-GVVLSPNWPEAYGKGQDCIWGLHVEEDKRVMLDIRVLRLGAG-----DVLTFYDGDDLTARILGQYTGAR 630
Cdd:cd00041     1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2024366606 631 GRFKLFASSADVTIQFQSDPGAGvfayRQGFVIHFS 666
Cdd:cd00041    81 LPPPIISSGNSLTVRFRSDSSVT----GRGFKATYS 112
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 390-488 8.30e-19

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 82.44  E-value: 8.30e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606  390 GRVVSPGFPGNYSNNLTCHWLLEAPVGHRLHLHFEKVSLAEDD----DRLIIRNGNNVEApPVYDSYEVEYLPIEGLLST 465
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSDnceyDYVEIYDGPSASS-PLLGRFCGSEAPPPVISSS 79

                           90       100
                   ....*....|....*....|...
gi 2024366606  466 GRHFFVELTTDSSGAAAGMALRY 488
Cdd:smart00042  80 SNSLTLTFVSDSSVQKRGFSARY 102
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 566-665 1.60e-15

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 73.19  E-value: 1.60e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606  566 GVVLSPNWPEAYGKGQDCIWGLHVEEDKRVMLDIRVLRLGAG-----DVLTFYDGDDLTARILGQYTGARGRFKLFAS-S 639
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSdnceyDYVEIYDGPSASSPLLGRFCGSEAPPPVISSsS 80

                           90       100
                   ....*....|....*....|....*.
gi 2024366606  640 ADVTIQFQSDPGAGvfayRQGFVIHF 665
Cdd:smart00042  81 NSLTLTFVSDSSVQ----KRGFSARY 102
CUB pfam00431
CUB domain;
380-488 2.29e-14

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 70.02  E-value: 2.29e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 380 CGGAIRNATvGRVVSPGFPGNYSNNLTCHWLLEAPVGHRLHLHFEKVSLAEDD----DRLIIRNGNNvEAPPVYDSYEVE 455
Cdd:pfam00431   1 CGGVLTDSS-GSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHDecgyDYVEIRDGPS-ASSPLLGRFCGS 78

                          90       100       110
                  ....*....|....*....|....*....|...
gi 2024366606 456 YLPiEGLLSTGRHFFVELTTDSSGAAAGMALRY 488
Cdd:pfam00431  79 GIP-EDIVSSSNQMTIKFVSDASVQKRGFKATY 110
CUB pfam00431
CUB domain;
557-665 3.42e-14

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 69.63  E-value: 3.42e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 557 CSGELMDTAGVVLSPNWPEAYGKGQDCIWGLHVEEDKRVML-----DIRVLRLGAGDVLTFYDGDDLTARILGQYTGARG 631
Cdd:pfam00431   1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLtfqdfELEDHDECGYDYVEIRDGPSASSPLLGRFCGSGI 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2024366606 632 RFKLFASSADVTIQFQSDPGagvfAYRQGFVIHF 665
Cdd:pfam00431  81 PEDIVSSSNQMTIKFVSDAS----VQKRGFKATY 110
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 674-859 5.99e-13

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 70.07  E-value: 5.99e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 674 CPELPDIANGWKTASQPELlhGTVVTFHCYPGFELAGADLLMCHW----DLTWSGDLPSCERVTtCRDPGDAEHSRRVVS 749
Cdd:PHA02927   86 CPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESVK-CQSPPSISNGRHNGY 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 750 SPKFPVGSTVRFVCDKGYVLAGAGLLTChdraSGGpKWSDRlPKCipeAYEPCHNPGVPAGGRQSPERRLYPAGSTLRFS 829
Cdd:PHA02927  163 EDFYTDGSVVTYSCNSGYSLIGNSGVLC----SGG-EWSDP-PTC---QIVKCPHPTISNGYLSSGFKRSYSYNDNVDFK 233

                         170       180       190
                  ....*....|....*....|....*....|
gi 2024366606 830 CTAGRALLGEGNLRCLPGHPsrWSGSPPIC 859
Cdd:PHA02927  234 CKYGYKLSGSSSSTCSPGNT--WQPELPKC 261
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 674-730 1.33e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 63.25  E-value: 1.33e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2024366606 674 CPELPDIANGWKTASQPELLHGTVVTFHCYPGFELAGADLLMCHWDLTWSGDLPSCE 730
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 674-729 1.31e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 60.23  E-value: 1.31e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024366606  674 CPELPDIANGWKTASQPELLHGTVVTFHCYPGFELAGADLLMCHWDLTWSGDLPSC 729
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
496-553 8.11e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 58.28  E-value: 8.11e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024366606 496 CYEPF-VKYGNFTTSDPRYPVGTTVEFSCHPGYTLeQGSTIIECVDpsDPQWNETEPAC 553
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRL-VGSPTITCQE--DGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 735-795 1.16e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 57.86  E-value: 1.16e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024366606 735 CRDPGDAEHSRRVVSSPKFPVGSTVRFVCDKGYVLAGAGLLTChdRASGGpkWSDRLPKCI 795
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITC--TENGG--WSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 499-554 2.34e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.70  E-value: 2.34e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024366606 499 PFVKYGNFTTSDPRYPVGTTVEFSCHPGYTLeQGSTIIECVdpSDPQWNETEPACR 554
Cdd:cd00033     5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTL-VGSSTITCT--ENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 735-794 7.33e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 55.61  E-value: 7.33e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606  735 CRDPGDAEHSRRVVSSPKFPVGSTVRFVCDKGYVLAGAGLLTCHDrasgGPKWSDRLPKC 794
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLE----NGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 802-860 1.09e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 55.16  E-value: 1.09e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024366606 802 CHNPGVPAGGRQSPERRLYPAGSTLRFSCTAGRALLGEGNLRCLPGhpSRWSGSPPICK 860
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN--GGWSPPPPTCE 57
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 209-316 1.42e-09

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 56.65  E-value: 1.42e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 209 CNRTL-AGPEGWLVSPEPaSAPYDSSMDCTYTISVYPGYGVEIKVQNISLADGET-----LTVESAGGLEPAVLANESFL 282
Cdd:cd00041     1 CGGTLtASTSGTISSPNY-PNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPNcsydyLEIYDGPSTSSPLLGRFCGS 79

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2024366606 283 LRGQVIRSPANVLTLRFQSPRSTSPGSYRFQYQA 316
Cdd:cd00041    80 TLPPPIISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 499-553 1.43e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 54.45  E-value: 1.43e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024366606  499 PFVKYGNFTTSDPRYPVGTTVEFSCHPGYTLeQGSTIIECVDpsDPQWNETEPAC 553
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTL-IGSSTITCLE--NGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 735-860 3.68e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 58.51  E-value: 3.68e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 735 CRDPGDAEHSRRVVSSPKFpvGSTVRFVCDKGYVLAGAGLLTCHDRASGGPKWSDRLPKCipEAYEpCHNPGVPAGGRQS 814
Cdd:PHA02927   86 CPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQLIGESKSYCELGSTGSMVWNPEAPIC--ESVK-CQSPPSISNGRHN 160

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 2024366606 815 PERRLYPAGSTLRFSCTAGRALLGEGNLRCLPGhpsRWSgSPPICK 860
Cdd:PHA02927  161 GYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGG---EWS-DPPTCQ 202
Sushi pfam00084
Sushi repeat (SCR repeat);
674-729 4.06e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 53.27  E-value: 4.06e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024366606 674 CPELPDIANGWKTASQPELLHGTVVTFHCYPGFELAGADLLMCHWDLTWSGDLPSC 729
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 674-795 6.27e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 58.13  E-value: 6.27e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 674 CPELPDIANGWKTASQPELLHGTVVTFHCYPGFELAGADLLMCHWDlTWSgDLPSCErVTTCRDPGDAEHSRRVVSSPKF 753
Cdd:PHA02927  148 CQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGG-EWS-DPPTCQ-IVKCPHPTISNGYLSSGFKRSY 224

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 2024366606 754 PVGSTVRFVCDKGYVLAGAGLLTChdraSGGPKWSDRLPKCI 795
Cdd:PHA02927  225 SYNDNVDFKCKYGYKLSGSSSSTC----SPGNTWQPELPKCV 262
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 802-859 1.82e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 51.37  E-value: 1.82e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2024366606  802 CHNPGVPAGGRQSPERRLYPAGSTLRFSCTAGRALLGEGNLRCLPGhpSRWSGSPPIC 859
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLEN--GTWSPPPPTC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 672-795 3.39e-08

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 55.33  E-value: 3.39e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 672 DTCPELPDIANGWKTASQPELLHGTVVTFHCYPG-----FELAGADLLMCHWDLTWSGDLPSCErVTTCRDPG-DAEHSR 745
Cdd:PHA02817   22 NKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCK-IIRCRFPAlQNGFVN 100

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2024366606 746 RVVSSPKFPVGSTVRFVCDKGYVLAGAGLLTCHDRASggpkWSDRLPKCI 795
Cdd:PHA02817  101 GIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSS----WIPKVPICS 146
PHA02639 PHA02639
EEV host range protein; Provisional
 735-860 5.49e-07

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 52.36  E-value: 5.49e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 735 CRDPGDAEHSRRVVSSPKFPVGSTVRFVCDKGYVLAGAGLLTChDRASGGPKWSDRLPKCIpeaYEPCHNPGVPAGGRQS 814
Cdd:PHA02639   22 CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTC-IKDKNNAIWSNKAPFCM---LKECNDPPSIINGKIY 97

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2024366606 815 PERRLYPAGSTLRFSCTAGR----ALLGEGNLRCLpgHPSRWSGSPPICK 860
Cdd:PHA02639   98 NKREMYKVGDEIYYVCNEHKgvqySLVGNEKITCI--QDKSWKPDPPICK 145
Sushi pfam00084
Sushi repeat (SCR repeat);
735-794 2.17e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.57  E-value: 2.17e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 735 CRDPGDAEHSRRVVSSPKFPVGSTVRFVCDKGYVLAGAGLLTChdraSGGPKWSDRLPKC 794
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITC----QEDGTWSPPFPEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 674-859 4.78e-06

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 49.66  E-value: 4.78e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 674 CPELPDIANGWKTASQPELLHGTVVTFHCYPGFELAGADLLMCHWD---LTWSGDLPSCeRVTTCRDPGDAEHSRRVVSS 750
Cdd:PHA02639   22 CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDknnAIWSNKAPFC-MLKECNDPPSIINGKIYNKR 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 751 PKFPVGSTVRFVCD--KG--YVLAGAGLLTCHDRASggpkWSDRLPKCipeAYEPCHNPGVPAGGRQS-PERRLYPAGST 825
Cdd:PHA02639  101 EMYKVGDEIYYVCNehKGvqYSLVGNEKITCIQDKS----WKPDPPIC---KMINCRFPALQNGYINGiPSNKKFYYKTR 173

                         170       180       190
                  ....*....|....*....|....*....|....
gi 2024366606 826 LRFSCTAGRALLGEGNLRClpGHPSRWSGSPPIC 859
Cdd:PHA02639  174 VGFSCKSGFDLVGEKYSTC--NINATWFPSIPTC 205
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 321-376 1.60e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 43.22  E-value: 1.60e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2024366606 321 CPFPARPAFGDVSVS--SLHPGGDARFRCTTGYQLQGAHLITCRNATRpfWSAREPQC 376
Cdd:cd00033     1 CPPPPVPENGTVTGSkgSYSYGSTVTYSCNEGYTLVGSSTITCTENGG--WSPPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 695-801 1.88e-05

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 47.77  E-value: 1.88e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 695 GTVVTFHCYPGFELAGADLLMCHWDlTWSGdLPSCERvtTCRDPgdaEHSRRVVSSPKFPVGSTVRFVCDKGYVLAGAGL 774
Cdd:PHA02954  150 GEHITINCDVGYEVIGASYISCTAN-SWNV-IPSCQQ--KCDIP---SLSNGLISGSTFSIGGVIHLSCKSGFTLTGSPS 222

                          90       100
                  ....*....|....*....|....*....
gi 2024366606 775 LTCHDrasggPKWSDRLPKCI--PEAYEP 801
Cdd:PHA02954  223 STCID-----GKWNPVLPICVrsNEEFDP 246
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 321-376 2.00e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.90  E-value: 2.00e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2024366606  321 CPFPARPAFGDVSVSS--LHPGGDARFRCTTGYQLQGAHLITCRNATRpfWSAREPQC 376
Cdd:smart00032   1 CPPPPDIENGTVTSSSgtYSYGDTVTYSCDPGYTLIGSSTITCLENGT--WSPPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 674-795 1.21e-04

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 45.04  E-value: 1.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 674 CPELPDIANGwKTASQPELLH-GTVVTFHC--YPG--FELAGADLLMCHWDLTWSGDLPSCeRVTTCRDPG-DAEHSRRV 747
Cdd:PHA02639   85 CNDPPSIING-KIYNKREMYKvGDEIYYVCneHKGvqYSLVGNEKITCIQDKSWKPDPPIC-KMINCRFPAlQNGYINGI 162

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2024366606 748 VSSPKFPVGSTVRFVCDKGYVLAGAGLLTCHDRASggpkWSDRLPKCI 795
Cdd:PHA02639  163 PSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINAT----WFPSIPTCV 206
PHA02831 PHA02831
EEV host range protein; Provisional
 674-798 5.93e-04

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 42.67  E-value: 5.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 674 CPELPDIANGWKTASQPELLHGTVVTFHC----YPGFELAGADLLMChWDLTWSGDLPSCeRVTTCRDPGdAEHSRRVVS 749
Cdd:PHA02831   78 CKDPVTILNGYIKNKKDQYSFGDSVTYACkvnkLEKYSIVGNETVKC-INKQWVPKYPVC-KLIRCKYPA-LQNGFLNVF 154

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2024366606 750 SPKFPVGSTVRFVCDKGYVLAGAGLLTCHDRASggpkWSDRLPKCIPEA 798
Cdd:PHA02831  155 EKKFYYGDIVNFKCKKGFILLGSSVSTCDINSI----WYPGIPKCVKDK 199
PHA02831 PHA02831
EEV host range protein; Provisional
 668-729 1.79e-03

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 41.13  E-value: 1.79e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024366606 668 VPRNDTCP----ELPDIANGWKTASQPELLHGTVVTFHCYPGFELAGADLLMCHWDLTWSGDLPSC 729
Cdd:PHA02831  130 VPKYPVCKlircKYPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKC 195
Sushi pfam00084
Sushi repeat (SCR repeat);
802-859 3.20e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 36.71  E-value: 3.20e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2024366606 802 CHNPGVPAGGRQSPERRLYPAGSTLRFSCTAGRALLGEGNLRCLPGhpSRWSGSPPIC 859
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQED--GTWSPPFPEC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 752-886 4.05e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 40.45  E-value: 4.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024366606 752 KFPVGSTVRFVCDKGYVLAGAGLLTCHDRAsggpkWsDRLPKCIPEAYEPCHNPGVPAGGRqsperrlYPAGSTLRFSCT 831
Cdd:PHA02954  146 KYSFGEHITINCDVGYEVIGASYISCTANS-----W-NVIPSCQQKCDIPSLSNGLISGST-------FSIGGVIHLSCK 212

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2024366606 832 AGRALLGEGNLRCLPGhpsRWSGSPPICkaasydeFYSNRNLDAVAKAVPSETAL 886
Cdd:PHA02954  213 SGFTLTGSPSSTCIDG---KWNPVLPIC-------VRSNEEFDPVDDGPDDETDL 257
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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