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Conserved domains on  [gi|955331144|ref|XP_014633489|]
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sulfoquinovosyl transferase SQD2 isoform X2 [Glycine max]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02871 super family cl33585
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
 7-285 0e+00

UDP-sulfoquinovose:DAG sulfoquinovosyltransferase


The actual alignment was detected with superfamily member PLN02871:

Pssm-ID: 215469 [Multi-domain]  Cd Length: 465  Bit Score: 550.08  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144   7 YIPRYTFSWLVKPMWLIIKFLHRAADLTLVPSAAIAGDLLAARVTAANKIRLWNKGVDSEKFHPKYRSHEMRLRLSNGEP 86
Cdd:PLN02871 182 YIPRYTFSWLVKPMWDIIRFLHRAADLTLVTSPALGKELEAAGVTAANRIRVWNKGVDSESFHPRFRSEEMRARLSGGEP 261

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  87 DKPLIVHVGRLGVEKSLDFLK----RLPDARIAFVGDGPYREELEKMFEGMPAVFTGMLVGEELSQAYASGDVFVMPSES 162
Cdd:PLN02871 262 EKPLIVYVGRLGAEKNLDFLKrvmeRLPGARLAFVGDGPYREELEKMFAGTPTVFTGMLQGDELSQAYASGDVFVMPSES 341

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 163 ETLGLVVLEAMSSGIPVVAACAGGIPDIIPVDQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAAREEMEKYDWK 242
Cdd:PLN02871 342 ETLGFVVLEAMASGVPVVAARAGGIPDIIPPDQEGKTGFLYTPGDVDDCVEKLETLLADPELRERMGAAAREEVEKWDWR 421

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 955331144 243 EATRKIRNEQYNAAIWFWRKKRAQLLRPFQWLAKRFFPSPQVN 285
Cdd:PLN02871 422 AATRKLRNEQYSAAIWFWRKKRAQLLGPVQWLPAQLFPAPEVN 464
 
Name Accession Description Interval E-value
PLN02871 PLN02871
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
 7-285 0e+00

UDP-sulfoquinovose:DAG sulfoquinovosyltransferase


Pssm-ID: 215469 [Multi-domain]  Cd Length: 465  Bit Score: 550.08  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144   7 YIPRYTFSWLVKPMWLIIKFLHRAADLTLVPSAAIAGDLLAARVTAANKIRLWNKGVDSEKFHPKYRSHEMRLRLSNGEP 86
Cdd:PLN02871 182 YIPRYTFSWLVKPMWDIIRFLHRAADLTLVTSPALGKELEAAGVTAANRIRVWNKGVDSESFHPRFRSEEMRARLSGGEP 261

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  87 DKPLIVHVGRLGVEKSLDFLK----RLPDARIAFVGDGPYREELEKMFEGMPAVFTGMLVGEELSQAYASGDVFVMPSES 162
Cdd:PLN02871 262 EKPLIVYVGRLGAEKNLDFLKrvmeRLPGARLAFVGDGPYREELEKMFAGTPTVFTGMLQGDELSQAYASGDVFVMPSES 341

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 163 ETLGLVVLEAMSSGIPVVAACAGGIPDIIPVDQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAAREEMEKYDWK 242
Cdd:PLN02871 342 ETLGFVVLEAMASGVPVVAARAGGIPDIIPPDQEGKTGFLYTPGDVDDCVEKLETLLADPELRERMGAAAREEVEKWDWR 421

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 955331144 243 EATRKIRNEQYNAAIWFWRKKRAQLLRPFQWLAKRFFPSPQVN 285
Cdd:PLN02871 422 AATRKLRNEQYSAAIWFWRKKRAQLLGPVQWLPAQLFPAPEVN 464
GT4-like cd03814
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 4-253 8.44e-93

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340842 [Multi-domain]  Cd Length: 365  Bit Score: 278.79  E-value: 8.44e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144   4 FSRYIPRYTFSWLVKPMWLIIKFLHRAADLTLVPSAAIAGDLLAarvTAANKIRLWNKGVDSEKFHPKYRSHEMRLRLsn 83
Cdd:cd03814  119 FPEYLSYYTLGPLSWLAWAYLRWFHNPFDTTLVPSPSIARELEG---HGFERVRLWPRGVDTELFHPSRRDAALRRRL-- 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  84 GEPDKPLIVHVGRLGVEKSLDFLKRL-------PDARIAFVGDGPYREELEkmFEGMPAVFTGMLVGEELSQAYASGDVF 156
Cdd:cd03814  194 GPPGRPLLLYVGRLAPEKNLEALLDAdlplaasPPVRLVVVGDGPARAELE--ARGPDVIFTGFLTGEELARAYASADVF 271

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 157 VMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIpvdQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAAREEM 236
Cdd:cd03814  272 VFPSRTETFGLVVLEAMASGLPVVAADAGGPRDIV---RPGGTGALVEPGDAAAFAAALRALLEDPELRRRMAARARAEA 348

                        250
                 ....*....|....*..
gi 955331144 237 EKYDWKEATRKIRNEQY 253
Cdd:cd03814  349 ERYSWEAFLDNLLDYYA 365
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 87-234 7.39e-31

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 112.75  E-value: 7.39e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144   87 DKPLIVHVGRLGVEKSLDFL--------KRLPDARIAFVGDGPYREELEKMFE--GMPA--VFTGMLVGEELSQAYASGD 154
Cdd:pfam00534   1 KKKIILFVGRLEPEKGLDLLikafallkEKNPNLKLVIAGDGEEEKRLKKLAEklGLGDnvIFLGFVSDEDLPELLKIAD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  155 VFVMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIpvdQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAARE 234
Cdd:pfam00534  81 VFVLPSRYEGFGIVLLEAMACGLPVIASDVGGPPEVV---KDGETGFLVKPNNAEALAEAIDKLLEDEELRERLGENARK 157
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 149-250 1.65e-26

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 100.45  E-value: 1.65e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 149 AYASGDVFVMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIpvdQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETM 228
Cdd:COG0438   17 LLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEVI---EDGETGLLVPPGDPEALAEAILRLLEDPELRRRL 93

                         90       100
                 ....*....|....*....|...
gi 955331144 229 GKAAREEME-KYDWKEATRKIRN 250
Cdd:COG0438   94 GEAARERAEeRFSWEAIAERLLA 116
stp2 TIGR03088
sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match ...
 40-237 1.11e-25

sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.


Pssm-ID: 132132 [Multi-domain]  Cd Length: 374  Bit Score: 104.42  E-value: 1.11e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144   40 AIAGDLLA-----ARVTAANKIRLWNkGVDSEKFHPKYRSHEMRLRLSNGEPDKPLIVHVGRLGVEKS--------LDFL 106
Cdd:TIGR03088 142 AVSRDLEDwlrgpVKVPPAKIHQIYN-GVDTERFHPSRGDRSPILPPDFFADESVVVGTVGRLQAVKDqptlvrafALLV 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  107 KRLPD----ARIAFVGDGPYREELEKMFEGMPAVFTGMLVGE--ELSQAYASGDVFVMPSESETLGLVVLEAMSSGIPVV 180
Cdd:TIGR03088 221 RQLPEgaerLRLVIVGDGPARGACEQMVRAAGLAHLVWLPGErdDVPALMQALDLFVLPSLAEGISNTILEAMASGLPVI 300

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 955331144  181 AACAGGIPDIIpvdQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAAREEME 237
Cdd:TIGR03088 301 ATAVGGNPELV---QHGVTGALVPPGDAVALARALQPYVSDPAARRAHGAAGRARAE 354
 
Name Accession Description Interval E-value
PLN02871 PLN02871
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
 7-285 0e+00

UDP-sulfoquinovose:DAG sulfoquinovosyltransferase


Pssm-ID: 215469 [Multi-domain]  Cd Length: 465  Bit Score: 550.08  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144   7 YIPRYTFSWLVKPMWLIIKFLHRAADLTLVPSAAIAGDLLAARVTAANKIRLWNKGVDSEKFHPKYRSHEMRLRLSNGEP 86
Cdd:PLN02871 182 YIPRYTFSWLVKPMWDIIRFLHRAADLTLVTSPALGKELEAAGVTAANRIRVWNKGVDSESFHPRFRSEEMRARLSGGEP 261

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  87 DKPLIVHVGRLGVEKSLDFLK----RLPDARIAFVGDGPYREELEKMFEGMPAVFTGMLVGEELSQAYASGDVFVMPSES 162
Cdd:PLN02871 262 EKPLIVYVGRLGAEKNLDFLKrvmeRLPGARLAFVGDGPYREELEKMFAGTPTVFTGMLQGDELSQAYASGDVFVMPSES 341

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 163 ETLGLVVLEAMSSGIPVVAACAGGIPDIIPVDQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAAREEMEKYDWK 242
Cdd:PLN02871 342 ETLGFVVLEAMASGVPVVAARAGGIPDIIPPDQEGKTGFLYTPGDVDDCVEKLETLLADPELRERMGAAAREEVEKWDWR 421

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 955331144 243 EATRKIRNEQYNAAIWFWRKKRAQLLRPFQWLAKRFFPSPQVN 285
Cdd:PLN02871 422 AATRKLRNEQYSAAIWFWRKKRAQLLGPVQWLPAQLFPAPEVN 464
GT4-like cd03814
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 4-253 8.44e-93

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340842 [Multi-domain]  Cd Length: 365  Bit Score: 278.79  E-value: 8.44e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144   4 FSRYIPRYTFSWLVKPMWLIIKFLHRAADLTLVPSAAIAGDLLAarvTAANKIRLWNKGVDSEKFHPKYRSHEMRLRLsn 83
Cdd:cd03814  119 FPEYLSYYTLGPLSWLAWAYLRWFHNPFDTTLVPSPSIARELEG---HGFERVRLWPRGVDTELFHPSRRDAALRRRL-- 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  84 GEPDKPLIVHVGRLGVEKSLDFLKRL-------PDARIAFVGDGPYREELEkmFEGMPAVFTGMLVGEELSQAYASGDVF 156
Cdd:cd03814  194 GPPGRPLLLYVGRLAPEKNLEALLDAdlplaasPPVRLVVVGDGPARAELE--ARGPDVIFTGFLTGEELARAYASADVF 271

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 157 VMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIpvdQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAAREEM 236
Cdd:cd03814  272 VFPSRTETFGLVVLEAMASGLPVVAADAGGPRDIV---RPGGTGALVEPGDAAAFAAALRALLEDPELRRRMAARARAEA 348

                        250
                 ....*....|....*..
gi 955331144 237 EKYDWKEATRKIRNEQY 253
Cdd:cd03814  349 ERYSWEAFLDNLLDYYA 365
GT4_UGDG-like cd03817
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ...
 7-251 9.28e-46

UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.


Pssm-ID: 340844 [Multi-domain]  Cd Length: 372  Bit Score: 157.83  E-value: 9.28e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144   7 YIPRYTFSWLVKPMWLIIKFLHRAaDLTLVPSAAIAGDLLAARVTaaNKIRLWNKGVDSEKFhPKYRSHEMRLRLsNGEP 86
Cdd:cd03817  125 YIPKGKLLVKAVVRKLVRRFYNHT-DAVIAPSEKIKDTLREYGVK--GPIEVIPNGIDLDKF-EKPLNTEERRKL-GLPP 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  87 DKPLIVHVGRLGVEKSLDFL-------KRLPDARIAFVGDGPYREELEKMFEGMPA----VFTGMLVGEELSQAYASGDV 155
Cdd:cd03817  200 DEPILLYVGRLAKEKNIDFLlrafaelKKEPNIKLVIVGDGPEREELKELARELGLadkvIFTGFVPREELPEYYKAADL 279

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 156 FVMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIpvdQDGKTSYLYNPGDFE-DCLSKLrpLLLNKELRETMGKAARE 234
Cdd:cd03817  280 FVFASTTETQGLVYLEAMAAGLPVVAAKDPAASELV---EDGENGFLFEPNDETlAEKLLH--LRENLELLRKLSKNAEI 354

                        250
                 ....*....|....*..
gi 955331144 235 EMEKYDWKEATRKIRNE 251
Cdd:cd03817  355 SAREFAFAKSVEKLYEE 371
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 24-250 6.75e-45

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 155.39  E-value: 6.75e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  24 IKFLHRAADLTLVPSAAIAGDLLAARVTAANKIRLWNKGVDSEKFHPKYRshemrlRLSNGEPDKPLIVHVGRLGVEKSL 103
Cdd:cd03801  134 AEALLRRADAVIAVSEALRDELRALGGIPPEKIVVIPNGVDLERFSPPLR------RKLGIPPDRPVLLFVGRLSPRKGV 207

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 104 DFL--------KRLPDARIAFVG-DGPYREELEKMFEGMPA--VFTGMLVGEELSQAYASGDVFVMPSESETLGLVVLEA 172
Cdd:cd03801  208 DLLlealakllRRGPDVRLVIVGgDGPLRAELEELELGLGDrvRFLGFVPDEELPALYAAADVFVLPSRYEGFGLVVLEA 287

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 955331144 173 MSSGIPVVAACAGGIPDIIPVDQDGktsYLYNPGDFEDCLSKLRPLLLNKELRETMGKAAREE-MEKYDWKEATRKIRN 250
Cdd:cd03801  288 MAAGLPVVATDVGGLPEVVEDGEGG---LVVPPDDVEALADALLRLLADPELRARLGRAARERvAERFSWERVAERLLD 363
GT4_WlbH-like cd03798
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ...
 23-256 3.32e-32

Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.


Pssm-ID: 340828 [Multi-domain]  Cd Length: 376  Bit Score: 122.10  E-value: 3.32e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  23 IIKFLHRAADLTLVPSAAIAgDLLAARVTAANKI-RLWNkGVDSEKFHPKYRshemRLRLsngEPDKPLIVHVGRLGVEK 101
Cdd:cd03798  143 LLRWALRRAARVIAVSKALA-EELVALGVPRDRVdVIPN-GVDPARFQPEDR----GLGL---PLDAFVILFVGRLIPRK 213

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 102 SLDFL--------KRLPDARIAFVGDGPYREELEKMFE--GMPA--VFTGMLVGEELSQAYASGDVFVMPSESETLGLVV 169
Cdd:cd03798  214 GIDLLleafarlaKARPDVVLLIVGDGPLREALRALAEdlGLGDrvTFTGRLPHEQVPAYYRACDVFVLPSRHEGFGLVL 293

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 170 LEAMSSGIPVVAACAGGIPDIIPvdqDGKTSYLYNPGDFEDCLSKLRpLLLNKELRETMGKAAREEM-EKYDWKEATRKI 248
Cdd:cd03798  294 LEAMACGLPVVATDVGGIPEVVG---DPETGLLVPPGDADALAAALR-RALAEPYLRELGEAARARVaERFSWVKAADRI 369


                 ....*...
gi 955331144 249 RnEQYNAA 256
Cdd:cd03798  370 A-AAYRDV 376
GT4_sucrose_synthase cd03800
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ...
 29-248 1.50e-31

sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.


Pssm-ID: 340830 [Multi-domain]  Cd Length: 398  Bit Score: 120.81  E-value: 1.50e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  29 RAADLTLVPSAAIAGDLLAARVTAANKIRLWNKGVDSEKFHPKYRSHEMRLRLsNGEPDKPLIVHVGRLGVEKSLDFL-- 106
Cdd:cd03800  162 EAADRVIASTPQEADELISLYGADPSRINVVPPGVDLERFFPVDRAEARRARL-LLPPDKPVVLALGRLDPRKGIDTLvr 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 107 ------KRLPDARIAFVG---------DGPYREELEKMFEGMPAV-FTGMLVGEELSQAYASGDVFVMPSESETLGLVVL 170
Cdd:cd03800  241 afaqlpELRELANLVLVGgpsddplsmDREELAELAEELGLIDRVrFPGRVSRDDLPELYRAADVFVVPSLYEPFGLTAI 320

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 955331144 171 EAMSSGIPVVAACAGGIPDIIpvdQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAAREE-MEKYDWKEATRKI 248
Cdd:cd03800  321 EAMACGTPVVATAVGGLQDIV---RDGRTGLLVDPHDPEALAAALRRLLDDPALWQRLSRAGLERaRAHYTWESVADQL 396
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 87-234 7.39e-31

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 112.75  E-value: 7.39e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144   87 DKPLIVHVGRLGVEKSLDFL--------KRLPDARIAFVGDGPYREELEKMFE--GMPA--VFTGMLVGEELSQAYASGD 154
Cdd:pfam00534   1 KKKIILFVGRLEPEKGLDLLikafallkEKNPNLKLVIAGDGEEEKRLKKLAEklGLGDnvIFLGFVSDEDLPELLKIAD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  155 VFVMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIpvdQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAARE 234
Cdd:pfam00534  81 VFVLPSRYEGFGIVLLEAMACGLPVIASDVGGPPEVV---KDGETGFLVKPNNAEALAEAIDKLLEDEELRERLGENARK 157
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
88-215 2.11e-30

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 111.06  E-value: 2.11e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144   88 KPLIVHVGRLGVE-KSLDFL--------KRLPDARIAFVGDGPyREELEKMFEGMPA--VFTGMLvgEELSQAYASGDVF 156
Cdd:pfam13692   1 RPVILFVGRLHPNvKGVDYLleavpllrKRDNDVRLVIVGDGP-EEELEELAAGLEDrvIFTGFV--EDLAELLAAADVF 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 955331144  157 VMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIpvdqDGKTSYLYNPGD---FEDCLSKL 215
Cdd:pfam13692  78 VLPSLYEGFGLKLLEAMAAGLPVVATDVGGIPELV----DGENGLLVPPGDpeaLAEAILRL 135
GT4_CapM-like cd03808
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ...
 50-253 2.77e-28

capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.


Pssm-ID: 340837 [Multi-domain]  Cd Length: 358  Bit Score: 111.15  E-value: 2.77e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  50 VTAANKIRLWNKGVDSEKFHPKYRSHEmrlrlsngePDKPLIVHVGRLGVEKSLDFL--------KRLPDARIAFVGDGP 121
Cdd:cd03808  160 IKKKKTVLIPGSGVDLDRFQYSPESLP---------SEKVVFLFVARLLKDKGIDELieaakilkKKGPNVRFLLVGDGE 230

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 122 YREELEKMFEGMPA----VFTGML--VGEELSQAyasgDVFVMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIpvdQ 195
Cdd:cd03808  231 LENPSEILIEKLGLegriEFLGFRsdVPELLAES----DVFVLPSYREGLPRSLLEAMAAGRPVITTDVPGCRELV---I 303

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 955331144 196 DGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAAREEME-KYDwkeatRKIRNEQY 253
Cdd:cd03808  304 DGVNGFLVPPGDVEALADAIEKLIEDPELRKEMGEAARKRVEeKFD-----EEKVVNKL 357
GT4_WavL-like cd03819
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ...
 15-235 1.83e-27

Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.


Pssm-ID: 340846 [Multi-domain]  Cd Length: 345  Bit Score: 108.60  E-value: 1.83e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  15 WLVKPMWLIIKFLHRAADLTLVPSAAIAGDLLAARVTAANKIRLWNKGVDSEKFHPkyrSHEMRLRLSNGEP-DKPLIVH 93
Cdd:cd03819  111 LATYHPKDFALAVRARGDRVIAVSELVRDHLIEALGVDPERIRVIPNGVDTDRFPP---EAEAEERAQLGLPeGKPVVGY 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  94 VGRLGVEKSLDF-------LKRLPDARIAFVGDGPYREELEKMFEGM---PAV-FTGMLvgEELSQAYASGDVFVMPSES 162
Cdd:cd03819  188 VGRLSPEKGWLLlvdaaaeLKDEPDFRLLVAGDGPERDEIRRLVERLglrDRVtFTGFR--EDVPAALAASDVVVLPSLH 265

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 955331144 163 ETLGLVVLEAMSSGIPVVAACAGGIPDIIPvdqDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAAREE 235
Cdd:cd03819  266 EEFGRVALEAMACGTPVVATDVGGAREIVV---HGRTGLLVPPGDAEALADAIRAAKLLPEAREKLQAAAALT 335
GT4_WbnK-like cd03807
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ...
 12-239 5.47e-27

Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.


Pssm-ID: 340836 [Multi-domain]  Cd Length: 362  Bit Score: 107.79  E-value: 5.47e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  12 TFSWLVKPMWLIIKFLHRAADLTLVPSAAiAGDLLAARVTAANKIRLWNKGVDSEKFHPKY-RSHEMRLRLSNGEpDKPL 90
Cdd:cd03807  115 IPQRLTRLVRKLCLLLSKFSPATVANSSA-VAEFHQEQGYAKNKIVVIYNGIDLFKLSPDDaSRARARRRLGLAE-DRRV 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  91 IVHVGRLGVEKSLDFL--------KRLPDARIAFVGDGPYREELEKMFE--GMPA--VFTGmlVGEELSQAYASGDVFVM 158
Cdd:cd03807  193 IGIVGRLHPVKDHSDLlraaallvETHPDLRLLLVGRGPERPNLERLLLelGLEDrvHLLG--ERSDVPALLPAMDIFVL 270

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 159 PSESETLGLVVLEAMSSGIPVVAACAGGIPDIIpvdqDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAAREEMEK 238
Cdd:cd03807  271 SSRTEGFPNALLEAMACGLPVVATDVGGAAELV----DDGTGFLVPAGDPQALADAIRALLEDPEKRARLGRAARERIAN 346


                 .
gi 955331144 239 Y 239
Cdd:cd03807  347 E 347
GT4-like cd05844
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar ...
 25-234 8.90e-27

glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to glycosyltransferase family 4 (GT4). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340860 [Multi-domain]  Cd Length: 365  Bit Score: 107.15  E-value: 8.90e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  25 KFLHRAADLTLVPSAAIAGDLLAARVtAANKIRLWNKGVDSEKFHPKYRShemrlrlsngePDKPLIVHVGRLGVEKSLD 104
Cdd:cd05844  138 RALQRPAALFVAVSGFIRDRLLARGL-PAERIHVHYIGIDPAKFAPRDPA-----------ERAPTILFVGRLVEKKGCD 205

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 105 FL--------KRLPDARIAFVGDGPYREELEKMFEGMPAV-FTGMLVGEELSQAYASGDVFVMPS------ESETLGLVV 169
Cdd:cd05844  206 VLieafrrlaARHPTARLVIAGDGPLRPALQALAAALGRVrFLGALPHAEVQDWMRRAEIFCLPSvtaasgDSEGLGIVL 285

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 955331144 170 LEAMSSGIPVVAACAGGIPDIIpvdQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAARE 234
Cdd:cd05844  286 LEAAACGVPVVSSRHGGIPEAI---LDGETGFLVPEGDVDALADALQALLADRALADRMGGAARA 347
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 149-250 1.65e-26

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 100.45  E-value: 1.65e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 149 AYASGDVFVMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIpvdQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETM 228
Cdd:COG0438   17 LLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEVI---EDGETGLLVPPGDPEALAEAILRLLEDPELRRRL 93

                         90       100
                 ....*....|....*....|...
gi 955331144 229 GKAAREEME-KYDWKEATRKIRN 250
Cdd:COG0438   94 GEAARERAEeRFSWEAIAERLLA 116
stp2 TIGR03088
sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match ...
 40-237 1.11e-25

sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.


Pssm-ID: 132132 [Multi-domain]  Cd Length: 374  Bit Score: 104.42  E-value: 1.11e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144   40 AIAGDLLA-----ARVTAANKIRLWNkGVDSEKFHPKYRSHEMRLRLSNGEPDKPLIVHVGRLGVEKS--------LDFL 106
Cdd:TIGR03088 142 AVSRDLEDwlrgpVKVPPAKIHQIYN-GVDTERFHPSRGDRSPILPPDFFADESVVVGTVGRLQAVKDqptlvrafALLV 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  107 KRLPD----ARIAFVGDGPYREELEKMFEGMPAVFTGMLVGE--ELSQAYASGDVFVMPSESETLGLVVLEAMSSGIPVV 180
Cdd:TIGR03088 221 RQLPEgaerLRLVIVGDGPARGACEQMVRAAGLAHLVWLPGErdDVPALMQALDLFVLPSLAEGISNTILEAMASGLPVI 300

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 955331144  181 AACAGGIPDIIpvdQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAAREEME 237
Cdd:TIGR03088 301 ATAVGGNPELV---QHGVTGALVPPGDAVALARALQPYVSDPAARRAHGAAGRARAE 354
GT4_BshA-like cd04962
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ...
 54-238 4.14e-25

N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340859 [Multi-domain]  Cd Length: 370  Bit Score: 102.82  E-value: 4.14e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  54 NKIRLWNKGVDSEKFHPKYRSHEMRLRLsnGEPDKPLIVHVGRL-GVEKSLDFL-------KRLPdARIAFVGDGPYREE 125
Cdd:cd04962  164 KDIEVIHNFIDEDVFKRKPAGALKRRLL--APPDEKVVIHVSNFrPVKRIDDVVrvfarvrRKIP-AKLLLVGDGPERVP 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 126 LEKMFEGM----PAVFTGMLvgEELSQAYASGDVFVMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIpvdQDGKTSY 201
Cdd:cd04962  241 AEELARELgvedRVLFLGKQ--DDVEELLSIADLFLLPSEKESFGLAALEAMACGVPVVSSNAGGIPEVV---KHGETGF 315

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 955331144 202 LYNPGDFEDCLSKLRPLLLNKELRETMGKAAREEMEK 238
Cdd:cd04962  316 LSDVGDVDAMAKSALSILEDDELYNRMGRAARKRAAE 352
GT4_WcaC-like cd03825
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ...
 29-239 4.95e-25

putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.


Pssm-ID: 340851 [Multi-domain]  Cd Length: 364  Bit Score: 102.41  E-value: 4.95e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  29 RAADLTLV-PSAAIAGDLLAARVTAANKIRLWNKGVDSEKFHPKYRShEMRLRLsNGEPDKPLI------VHVGRLGV-- 99
Cdd:cd03825  135 AKKRLTIVaPSRWLADMVRRSPLLKGLPVVVIPNGIDTEIFAPVDKA-KARKRL-GIPQDKKVIlfgaesVTKPRKGFde 212

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 100 -EKSLDFLKRLPDARIAFVG-DGPYREELekmfeGMPAVFTGML-VGEELSQAYASGDVFVMPSESETLGLVVLEAMSSG 176
Cdd:cd03825  213 lIEALKLLATKDDLLLVVFGkNDPQIVIL-----PFDIISLGYIdDDEQLVDIYSAADLFVHPSLADNLPNTLLEAMACG 287

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 955331144 177 IPVVAACAGGIPDIIpvdQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAAREEMEKY 239
Cdd:cd03825  288 TPVVAFDTGGSPEIV---QHGVTGYLVPPGDVQALAEAIEWLLANPKERESLGERARALAENH 347
GT4_MtfB-like cd03809
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ...
 8-250 1.48e-24

glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.


Pssm-ID: 340838 [Multi-domain]  Cd Length: 362  Bit Score: 100.90  E-value: 1.48e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144   8 IPRYTFSWLVKPMWLIIKFLHRA----ADLTLVPSAAIAGDLLAARVTAANKIRLWNKGVDSEKFHPkyRSHEMRLRLSN 83
Cdd:cd03809  112 IPLRYPEFFPKRFRLYYRLLLPIslrrADAIITVSEATRDDIIKFYGVPPEKIVVIPLGVDPSFFPP--ESAAVLIAKYL 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  84 gePDKPLIVHVGRLGVEKSLDFL--------KRLPDARIAFVG-DGPYREELEKMFEGMPA----VFTGMLVGEELSQAY 150
Cdd:cd03809  190 --LPEPYFLYVGTLEPRKNHERLlkafallkKQGGDLKLVIVGgKGWEDEELLDLVKKLGLggrvRFLGYVSDEDLPALY 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 151 ASGDVFVMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIpvdqdGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGK 230
Cdd:cd03809  268 RGARAFVFPSLYEGFGLPVLEAMACGTPVIASNISVLPEVA-----GDAALYFDPLDPESIADAILRLLEDPSLREELIR 342

                        250       260
                 ....*....|....*....|
gi 955331144 231 AAREEMEKYDWKEATRKIRN 250
Cdd:cd03809  343 KGLERAKKFSWEKTAEKTLE 362
GT4_WbuB-like cd03794
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ...
 14-248 4.76e-24

Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.


Pssm-ID: 340825 [Multi-domain]  Cd Length: 391  Bit Score: 100.11  E-value: 4.76e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  14 SWLVKPMWLIIKFLHRAADLTLVPSAAIAgDLLAARVTAANKIRLWNKGVDSEKFhpkYRSHEMRLRLSNGEPDKPLIVH 93
Cdd:cd03794  147 GSLLKLLKKLERKLYRLADAIIVLSPGLK-EYLLRKGVPKEKIIVIPNWADLEEF---KPPPKDELRKKLGLDDKFVVVY 222

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  94 VGRLGVEKSLDF-------LKRLPDARIAFVGDGPYREELEKMF--EGMPAV-FTGMLVGEELSQAYASGDVFVMP-SES 162
Cdd:cd03794  223 AGNIGKAQGLETlleaaerLKRRPDIRFLFVGDGDEKERLKELAkaRGLDNVtFLGRVPKEEVPELLSAADVGLVPlKDN 302

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 163 ETLGLVV----LEAMSSGIPVVAACAGGIPDIIpvdQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAAREE-ME 237
Cdd:cd03794  303 PANRGSSpsklFEYMAAGKPILASDDGGSDLAV---EINGCGLVVEPGDPEALADAILELLDDPELRRAMGENGRELaEE 379

                        250
                 ....*....|.
gi 955331144 238 KYDWKEATRKI 248
Cdd:cd03794  380 KFSREKLADRL 390
GT4_AmsD-like cd03820
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ...
 91-242 4.79e-23

amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.


Pssm-ID: 340847 [Multi-domain]  Cd Length: 351  Bit Score: 96.54  E-value: 4.79e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  91 IVHVGRLGVEKSLDFL--------KRLPDARIAFVGDGPYREELEKMFEG---------MPAVftgmlvgEELSQAYASG 153
Cdd:cd03820  184 ILAVGRLTYQKGFDLLieawaliaKKHPDWKLRIYGDGPEREELEKLIDKlgledrvklLGPT-------KNIAEEYANS 256

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 154 DVFVMPSESETLGLVVLEAMSSGIPVVA-ACAGGIPDIIpvdQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAA 232
Cdd:cd03820  257 SIFVLSSRYEGFPMVLLEAMAYGLPIISfDCPTGPSEII---EDGENGLLVPNGDVDALAEALLRLMEDEELRKKMGKNA 333

                        170
                 ....*....|
gi 955331144 233 REEMEKYDWK 242
Cdd:cd03820  334 RKNAERFSIE 343
GT4_Bme6-like cd03821
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ...
 49-250 7.70e-23

Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.


Pssm-ID: 340848 [Multi-domain]  Cd Length: 377  Bit Score: 96.67  E-value: 7.70e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  49 RVTAANKIRLWNKGVDSEKFHPKYRshemRLRLSNGEPDKPLIVHVGRLGVEKSLDFLKR--------LPDARIAFVG-- 118
Cdd:cd03821  169 RFGLEPPIAVIPNGVDIPEFDPGLR----DRRKHNGLEDRRIILFLGRIHPKKGLDLLIRaarklaeqGRDWHLVIAGpd 244

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 119 DGPYREELEKMFE---GMPAVFTGMLVGEELSQAYASGDVFVMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIpVDQ 195
Cdd:cd03821  245 DGAYPAFLQLQSSlglGDRVTFTGPLYGEAKWALYASADLFVLPSYSENFGNVVAEALACGLPVVITDKCGLSELV-EAG 323

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 955331144 196 DGKTSYLynpgDFEDCLSKLRPLLLNKELRET---MGKAAREEMEKYDWKEATRKIRN 250
Cdd:cd03821  324 CGVVVDP----NVSSLAEALAEALRDPADRKRlgeMARRARQVEENFSWEAVAGQLGE 377
GT4_GT28_WabH-like cd03811
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ...
 15-239 6.95e-21

family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.


Pssm-ID: 340839 [Multi-domain]  Cd Length: 351  Bit Score: 90.88  E-value: 6.95e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  15 WLVKPMWLIIKFLHRAaDLTLVPSAAIAGDLLAARVTAANKIRLWNKGVDSEKFHPKyrsheMRLRLSNGEPDKPLIVHV 94
Cdd:cd03811  121 YLKKKLLLKLKLYKKA-DKIVCVSKGIKEDLIRLGPSPPEKIEVIYNPIDIDRIRAL-----AKEPILNEPEDGPVILAV 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  95 GRLGVEKSLDFL--------KRLPDARIAFVGDGPYREELEKMFE--GMPA--VFTGmlvgeELSQAY---ASGDVFVMP 159
Cdd:cd03811  195 GRLDPQKGHDLLieafaklrKKYPDVKLVILGDGPLREELEKLAKelGLAErvIFLG-----FQSNPYpylKKADLFVLS 269

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 160 SESETLGLVVLEAMSSGIPVVAACAGGIPDIIpvdQDGKTSYLYNPGD---FEDCLSKLRPLLLNKELRETMGKAAREEM 236
Cdd:cd03811  270 SRYEGFPNVLLEAMALGTPVVSTDCPGPREIL---DDGENGLLVPDGDaaaLAGILAALLQKKLDAALRERLAKAQEAVF 346


                 ...
gi 955331144 237 EKY 239
Cdd:cd03811  347 REY 349
MSMEG_0565_glyc TIGR04047
glycosyltransferase, MSMEG_0565 family; A conserved gene cluster found sporadically from ...
 29-247 1.31e-20

glycosyltransferase, MSMEG_0565 family; A conserved gene cluster found sporadically from Actinobacteria to Proteobacteria to Cyanobacteria features a radical SAM protein, an N-acetyltransferase, an oxidoreductase, and two additional proteins whose functional classes are unclear. The metabolic role of the cluster is probably biosynthetic. This glycosyltransferase, named from member MSMEG_0565 from Mycobacterium smegmatis, occurs in most but not all instances of the cluster. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 274943 [Multi-domain]  Cd Length: 373  Bit Score: 90.15  E-value: 1.31e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144   29 RAADLTLVPSAAIAGDLLAARVTAANKIrlwNKGVDSEKFHPKYRSHEMRLRLSNGEPDKPLIVHVGrlGVEK---SLDF 105
Cdd:TIGR04047 137 VEADAVLCVSAAWAAELRAEWGIDATVV---PNGVDAARFSPAADAADAALRRRLGLRGGPYVLAVG--GIEPrknTIDL 211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  106 L-------KRLPDARIAFVGD------GPYREELEKMFEGM-----PAVFTGMLVGEELSQAYASGDVFVMPSESETLGL 167
Cdd:TIGR04047 212 LeafallrARRPQAQLVIAGGatlfdyDAYRREFRARAAELgvdpgPVVITGPVPDADLPALYRCADAFAFPSLKEGFGL 291

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  168 VVLEAMSSGIPVVAacaggiPDIIPV-----DQDGKTSYLYNPGDFEDCLSklrpLLLNKELRETMGKAAREEMEKYDWK 242
Cdd:TIGR04047 292 VVLEALASGIPVVA------SDIAPFteylgRFDAAWADPSDPDSIADALA----LALDPARRPALRAAGPELAARYTWD 361


                  ....*
gi 955331144  243 EATRK 247
Cdd:TIGR04047 362 ASARA 366
GT4_WfcD-like cd03795
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most ...
 15-238 8.82e-20

Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340826 [Multi-domain]  Cd Length: 355  Bit Score: 87.71  E-value: 8.82e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  15 WLVKPmwLIIKFLHRAAdlTLVPSAAIAGD----LLAARvtaaNKIRLWNKGVDSEKFhPKYRSHEMRLRLSNgePDKPL 90
Cdd:cd03795  125 KLYKP--LMTRFLRRAD--RIIATSPNYVEtsptLREFK----NKVRVIPLGIDKNVY-NIPRVDFENIKREK--KGKKI 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  91 IVHVGRLGVEKSLDFL---KRLPDARIAFVGDGPYREELEKMFE--GMPAV-FTGMLVGEELSQAYASGDVFVMPS--ES 162
Cdd:cd03795  194 FLFIGRLVYYKGLDYLieaAQYLNYPIVIGGEGPLKPDLEAQIElnLLDNVkFLGRVDDEEKVIYLHLCDVFVFPSvlRS 273

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 955331144 163 ETLGLVVLEAMSSGIPVVA-ACAGGIPdiiPVDQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAAREEMEK 238
Cdd:cd03795  274 EAFGIVLLEAMMCGKPVIStNIGTGVP---YVNNNGETGLVVPPKDPDALAEAIDKLLSDEELRESYGENAKKRFEE 347
GT4_ExpE7-like cd03823
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ...
 21-234 1.31e-18

glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).


Pssm-ID: 340850 [Multi-domain]  Cd Length: 357  Bit Score: 84.30  E-value: 1.31e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  21 WLI---IKFLHRAADLTLVPSAAIAGDLLAARVTAANKIRLWNkGVDSEKfhpkyrshemRLRLSNGEPDKPLIV-HVGR 96
Cdd:cd03823  131 WLLcprQFLFKKGGDAVLAPSRFTANLHEANGLFSARISVIPN-AVEPDL----------APPPRRRPGTERLRFgYIGR 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  97 LGVEKSLDFL----KRLP--DARIAFVGDGPyrEELEKMFEGMPAV-FTGMLVGEELSQAYASGDVFVMPSE-SETLGLV 168
Cdd:cd03823  200 LTEEKGIDLLveafKRLPreDIELVIAGHGP--LSDERQIEGGRRIaFLGRVPTDDIKDFYEKIDVLVVPSIwPEPFGLV 277

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 955331144 169 VLEAMSSGIPVVAACAGGIPDIIpvdQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAARE 234
Cdd:cd03823  278 VREAIAAGLPVIASDLGGIAELI---QPGVNGLLFAPGDAEDLAAAMRRLLTDPALLERLRAGAEP 340
Glycosyltransferase_GTB-type cd01635
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ...
 68-197 1.72e-18

glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340816 [Multi-domain]  Cd Length: 235  Bit Score: 82.07  E-value: 1.72e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  68 FHPKYRSHEMRLRLSNGEPDKPLI-----VHVGRLGVEKSLDFL--------KRLPDARIAFVGDGPYREELEKMFE--- 131
Cdd:cd01635   85 VHGPDSLESTRSELLALARLLVSLpladkVSVGRLVPEKGIDLLlealallkARLPDLVLVLVGGGGEREEEEALAAalg 164

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 955331144 132 -GMPAVFTGMLVGEELSQAYASG-DVFVMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIPVDQDG 197
Cdd:cd01635  165 lLERVVIIGGLVDDEVLELLLAAaDVFVLPSRSEGFGLVLLEAMAAGKPVIATDVGGIPEFVVDGENG 232
GT4_AmsK-like cd03799
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases ...
 53-248 2.55e-18

Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases found specifically in certain bacteria. AmsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor.


Pssm-ID: 340829 [Multi-domain]  Cd Length: 350  Bit Score: 83.65  E-value: 2.55e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  53 ANKIRLWNKGVDSEKFhpkyrshemRLRLSNGEPDKPL-IVHVGRLGVEKSLDF--------LKRLPDARIAFVGDGPYR 123
Cdd:cd03799  147 EKKIIVHRSGIDCNKF---------RFKPRYLPLDGKIrILTVGRLTEKKGLEYaieavaklAQKYPNIEYQIIGDGDLK 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 124 EELEKMFEGMPAVFTGMLVG----EELSQAYASGDVFVMPS------ESETLGLVVLEAMSSGIPVVAACAGGIPDIIpv 193
Cdd:cd03799  218 EQLQQLIQELNIGDCVKLLGwkpqEEIIEILDEADIFIAPSvtaadgDQDGPPNTLKEAMAMGLPVISTEHGGIPELV-- 295

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 955331144 194 dQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAAREEME-KYDWKEATRKI 248
Cdd:cd03799  296 -EDGVSGFLVPERDAEAIAEKLTYLIEHPAIWPEMGKAGRARVEeEYDINKLNDEL 350
GT4_WbdM_like cd04951
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ...
 46-228 3.92e-17

LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340857 [Multi-domain]  Cd Length: 360  Bit Score: 80.18  E-value: 3.92e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  46 LAARVTAANKIRLWNKGVDSEKFHpkyRSHEMRLRLSNG---EPDKPLIVHVGRLGVEKS--------LDFLKRLPDARI 114
Cdd:cd04951  146 IAKKAFSKNKSVPVYNGIDLNKFK---KDINVRLKIRNKlnlKNDEFVILNVGRLTEAKDypnlllaiSELILSKNDFKL 222

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 115 AFVGDGPYREELEKMFEGMPAVFTGMLVG--EELSQAYASGDVFVMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIp 192
Cdd:cd04951  223 LIAGDGPLRNELERLICNLNLVDRVILLGqiSNISEYYNAADLFVLSSEWEGFGLVVAEAMACERPVVATDAGGVAEVV- 301

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 955331144 193 vdqdgktsylynpGDFEDCLSKLRPLLLNKELRETM 228
Cdd:cd04951  302 -------------GDHNYVVPVSDPQLLAEKIKEIF 324
GT4-like cd03813
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 5-239 1.06e-16

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340841 [Multi-domain]  Cd Length: 474  Bit Score: 79.69  E-value: 1.06e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144   5 SRYIPRYtfswlVKPMWliIKFLHRAADLTLVPSAAIagdllaarVTAANKIRLWNK--------------GVDSEKFHP 70
Cdd:cd03813  219 STWIMGY-----IKKLW--IRFFERLGKLAYQQADKI--------ISLYEGNRRRQIrlgadpdktrvipnGIDIQRFAP 283

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  71 kyrshemrLRLSNGEPDKPLIVHVGRLGVEKSLD--------FLKRLPDARIAFVG----DGPYREELEKMFEGM----P 134
Cdd:cd03813  284 --------AREERPEKEPPVVGLVGRVVPIKDVKtfirafklVRRAMPDAEGWLIGpedeDPEYAQECKRLVASLglenK 355

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 135 AVFTGMlvgEELSQAYASGDVFVMPSESETLGLVVLEAMSSGIPVVAACAGGIPDII--PVDQDGKTSYLYNPGDFEDCL 212
Cdd:cd03813  356 VKFLGF---QNIKEYYPKLGLLVLTSISEGQPLVILEAMASGVPVVATDVGSCRELIygADDALGQAGLVVPPADPEALA 432

                        250       260
                 ....*....|....*....|....*..
gi 955331144 213 SKLRPLLLNKELRETMGKAAREEMEKY 239
Cdd:cd03813  433 EALIKLLRDPELRQAFGEAGRKRVEKY 459
GT4_CapH-like cd03812
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This ...
 62-202 7.70e-16

capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1).


Pssm-ID: 340840 [Multi-domain]  Cd Length: 357  Bit Score: 76.56  E-value: 7.70e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  62 GVDSEK--FHPKYRshEMRLRLSNGEpDKPLIVHVGRLGVEKSLDFL--------KRLPDARIAFVGDGPYREELEKMFE 131
Cdd:cd03812  166 GIDIEKykFNKEKR--RKRRKLLILE-DKLVLGHVGRFNEQKNHSFLidifeelkKKNPNVKLVLVGEGELKEKIKEKVK 242

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 955331144 132 GMP----AVFTGmlVGEELSQAYASGDVFVMPSESETLGLVVLEAMSSGIPVVaacaggIPDIIPVDQD--GKTSYL 202
Cdd:cd03812  243 ELGledkVIFLG--FRNDVSEILSAMDVFLFPSLYEGLPLVAVEAQASGLPCL------LSDTITKECDitNNVEFL 311
GT4_GtfA-like cd04949
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ...
 82-239 2.65e-15

accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340855 [Multi-domain]  Cd Length: 328  Bit Score: 74.65  E-value: 2.65e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  82 SNGEPDKPLIVHVGRLGVEKSLD--------FLKRLPDARIAFVGDGPYREELEKMFEGMPA---VFtgmLVG--EELSQ 148
Cdd:cd04949  154 SNHERKSNKIITISRLAPEKQLDhlieavakAVKKVPEITLDIYGYGEEREKLKKLIEELHLednVF---LKGyhSNLDQ 230

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 149 AYASGDVFVMPSESETLGLVVLEAMSSGIPVVA-ACAGGIPDIIpvdQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRET 227
Cdd:cd04949  231 EYQDAYLSLLTSQMEGFGLTLMEAIGHGLPVVSyDVKYGPSELI---EDGENGYLIEKNNIDALADKIIELLNDPEKLQQ 307

                        170
                 ....*....|..
gi 955331144 228 MGKAAREEMEKY 239
Cdd:cd04949  308 FSEESYKIAEKY 319
GT5_Glycogen_synthase_DULL1-like cd03791
Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 ...
 85-247 6.66e-15

Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 family of glycosyltransferases. Glycogen synthase (EC:2.4.1.21) catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family includes starch synthases of plants, such as DULL1 in Zea mays and glycogen synthases of various organisms.


Pssm-ID: 340822 [Multi-domain]  Cd Length: 474  Bit Score: 74.14  E-value: 6.66e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  85 EPDKPLIVHVGRLGVEKSLDFLKR-LP-----DARIAFVGDGPYREE-----LEKMFEGMPAVFTGMLvgEELSQ-AYAS 152
Cdd:cd03791  291 DPDAPLFGFVGRLTEQKGVDLILDaLPelleeGGQLVVLGSGDPEYEqafreLAERYPGKVAVVIGFD--EALAHrIYAG 368

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 153 GDVFVMPSESETLGLVVLEAMSSGIPVVAACAGGIPD-IIPVDQDGK--TSYL---YNPGDFEDCLSKLRPLLLNKELRE 226
Cdd:cd03791  369 ADFFLMPSRFEPCGLVQMYAMRYGTLPIVRRTGGLADtVFDYDPETGegTGFVfedYDAEALLAALRRALALYRNPELWR 448

                        170       180
                 ....*....|....*....|..
gi 955331144 227 TMGKAAreeMEK-YDWKEATRK 247
Cdd:cd03791  449 KLQKNA---MKQdFSWDKSAKE 467
GT4_AmsK-like cd04946
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most ...
 117-238 6.72e-14

amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmsK is involved in the biosynthesis of amylovoran, which functions as a virulence factor. It functions as a glycosyl transferase which transfers galactose from UDP-galactose to a lipid-linked amylovoran-subunit precursor. The members of this family are found mainly in bacteria and Archaea.


Pssm-ID: 340854 [Multi-domain]  Cd Length: 401  Bit Score: 70.95  E-value: 6.72e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 117 VGDGPYREELEKMFEGMP----AVFTGMLVGEELSQAYA--SGDVFVMPSESETLGLVVLEAMSSGIPVVAACAGGIPDI 190
Cdd:cd04946  263 IGGGPLKERLEKLAENKLenvkVNFTGEVSNKEVKQLYKenDVDVFVNVSESEGIPVSIMEAISFGIPVIATNVGGTREI 342

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 955331144 191 IpvdQDGKTSYLYN----PGDFEDCLSKlrpLLLNKELRETMGKAAREEMEK 238
Cdd:cd04946  343 V---ENETNGLLLDkdptPNEIVSSIMK---FYLDGGDYKTMKISARECWEE 388
GT4_trehalose_phosphorylase cd03792
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly ...
 80-258 3.73e-13

trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly catalyzes trehalose synthesis and degradation from alpha-glucose-1-phosphate (alpha-Glc-1-P) and glucose. The catalyzing activity includes the phosphorolysis of trehalose, which produce alpha-Glc-1-P and glucose, and the subsequent synthesis of trehalose. This family is most closely related to the GT4 family of glycosyltransferases.


Pssm-ID: 340823 [Multi-domain]  Cd Length: 378  Bit Score: 68.89  E-value: 3.73e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  80 RLSNGEPDKPLIVHVGR-------LGVEKS-LDFLKRLPDARIAFVG----DGP-----YREELEkMFEGMPAVFTGMLV 142
Cdd:cd03792  189 KPFVIDPERPYILQVARfdpskdpLGVIDAyKLFKRRAEEPQLVICGhgavDDPegsvvYEEVME-YAGDDHDIHVLRLP 267

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 143 G--EELSQAYASGDVFVMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIpvdQDGKTSYLYNPGdfeDCLSK-LRPLL 219
Cdd:cd03792  268 PsdQEINALQRAATVVLQLSTREGFGLTVSEALWKGKPVIATPAGGIPLQV---IDGETGFLVNSV---EGAAVrILRLL 341

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 955331144 220 LNKELRETMGKAAREEM-EKYDwkeATRKIRNEQYNAAIW 258
Cdd:cd03792  342 TDPELRRKMGLAAREHVrDNFL---ITGNLRAWLYLIAKL 378
GlgA COG0297
Glycogen synthase [Carbohydrate transport and metabolism];
85-247 6.93e-13

Glycogen synthase [Carbohydrate transport and metabolism];


Pssm-ID: 440066 [Multi-domain]  Cd Length: 476  Bit Score: 68.19  E-value: 6.93e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  85 EPDKPLIVHVGRLGVEKSLDFLKR-LP-----DARIAFVGDGPyrEELEKMFEGMPAVFTGMLV---G--EELS-QAYAS 152
Cdd:COG0297  292 DPDAPLIGMVSRLTEQKGLDLLLEaLDelleeDVQLVVLGSGD--PEYEEAFRELAARYPGRVAvyiGydEALAhRIYAG 369

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 153 GDVFVMPSESETLGLVVLEAMSSG-IPVVAAcAGGIPD-IIPVD--QDGKTSYL---YNPGDFEDCLSKLRPLLLNKELR 225
Cdd:COG0297  370 ADFFLMPSRFEPCGLNQMYALRYGtVPIVRR-TGGLADtVIDYNeaTGEGTGFVfdeYTAEALLAAIRRALALYRDPEAW 448

                        170       180
                 ....*....|....*....|...
gi 955331144 226 ETMGKAAreeMEK-YDWKEATRK 247
Cdd:COG0297  449 RKLQRNA---MKQdFSWEKSAKE 468
GT4_PIG-A-like cd03796
phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This ...
 63-194 4.75e-12

phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Phosphatidylinositol glycan-class A (PIG-A), an X-linked gene in humans, is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, a very early intermediate in glycosyl phosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is an important cellular structure that facilitates the attachment of many proteins to cell surfaces. Somatic mutations in PIG-A have been associated with Paroxysmal Nocturnal Hemoglobinuria (PNH), an acquired hematological disorder.


Pssm-ID: 340827 [Multi-domain]  Cd Length: 398  Bit Score: 65.72  E-value: 4.75e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  63 VDSEKFHPKYRSHEmrlrlsngePDKPLIVHVGRLGVEKSLDFL--------KRLPDARIAFVGDGPYREELEKMFEG-- 132
Cdd:cd03796  177 VDSSDFTPDPSKPD---------PNKITIVVISRLVYRKGIDLLvgiipricKKHPNVRFIIGGDGPKRIELEEMREKyq 247

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 955331144 133 -MPAV-FTGMLVGEELSQAYASGDVFVMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIPVD 194
Cdd:cd03796  248 lQDRVeLLGAVPHEEVRDVLVQGHIFLNTSLTEAFCIAIVEAASCGLLVVSTRVGGIPEVLPPD 311
GT4_ExpC-like cd03818
Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 ...
 30-240 2.32e-11

Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).


Pssm-ID: 340845 [Multi-domain]  Cd Length: 396  Bit Score: 63.54  E-value: 2.32e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  30 AADLTLVPSAaIAGDLLAArvTAANKIRLWNKGVDSEKFHPkyrSHEMRLRLSNG---EPDKPLIVHVGRlGVEKSLDF- 105
Cdd:cd03818  158 QADLGVTPTR-WQRSLFPA--AYRDRISVIHDGVDTDRLAP---DPAARLRLLNGtelKAGDPVITYVAR-NLEPYRGFh 230

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 106 ---------LKRLPDARIAFVGD------------GPYREELEKMFEGMPA--VFTGMLVGEELSQAYASGDVFVMPSES 162
Cdd:cd03818  231 vfmralpriQARRPDARVVVVGGdgvsygspppdgGSWKQKMLAELGVDLErvHFVGKVPYDQYVRLLQLSDAHVYLTYP 310

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 955331144 163 ETLGLVVLEAMSSGIPVVAACAGGIPDIIpvdQDGKTSYLYNPGDFEDCLSKLRPLLLNKELRETMGKAAREEMEKYD 240
Cdd:cd03818  311 FVLSWSLLEAMACGCPVIGSDTAPVREVI---RDGRNGLLVDFFDPDALAAAVLELLEDPDRAAALRRAARRTVERSD 385
PRK15484 PRK15484
lipopolysaccharide N-acetylglucosaminyltransferase;
35-259 3.01e-10

lipopolysaccharide N-acetylglucosaminyltransferase;


Pssm-ID: 185381 [Multi-domain]  Cd Length: 380  Bit Score: 60.19  E-value: 3.01e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  35 LVPSAAIAgDLLAARVTAANkIRLWNKGVDSEKFHpkyRSHEMRLRLS-NGEPDKPLIVHVGRLGVEKS----LDFLKRL 109
Cdd:PRK15484 144 IVPSQFLK-KFYEERLPNAD-ISIVPNGFCLETYQ---SNPQPNLRQQlNISPDETVLLYAGRISPDKGilllMQAFEKL 218

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 110 PDAR----IAFVGD---------GPYREELEKMFE--GMPAVFTGMLVGEELSQAYASGDVFVMPSE-SETLGLVVLEAM 173
Cdd:PRK15484 219 ATAHsnlkLVVVGDptasskgekAAYQKKVLEAAKriGDRCIMLGGQPPEKMHNYYPLADLVVVPSQvEEAFCMVAVEAM 298

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 174 SSGIPVVAACAGGIPDIIpvdQDGKTSY-LYNPGDFEDCLSKLRPLLLNKELRETMGKAAREEMEKYDWKEATRKIRNEQ 252
Cdd:PRK15484 299 AAGKPVLASTKGGITEFV---LEGITGYhLAEPMTSDSIISDINRTLADPELTQIAEQAKDFVFSKYSWEGVTQRFEEQI 375


                 ....*..
gi 955331144 253 YNaaiWF 259
Cdd:PRK15484 376 HN---WF 379
GT4_AviGT4-like cd03802
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is ...
 62-205 4.05e-10

UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.


Pssm-ID: 340832 [Multi-domain]  Cd Length: 333  Bit Score: 59.61  E-value: 4.05e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  62 GVDSEKFHPkyrshemrlrlsNGEPDKPLIvHVGRL----GVEKSLDFLKR--LPDARIAFVGDGPYREELEKMFEGMPA 135
Cdd:cd03802  156 GLDPADYRF------------QPDPEDYLA-FLGRIapekGLEDAIRVARRagLPLKIAGKVRDEDYFYYLQEPLPGPRI 222

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 955331144 136 VFTGMLVGEE----LSQAYAsgdVFVMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIpvdQDGKTSYLYNP 205
Cdd:cd03802  223 EFIGEVGHDEkqelLGGARA---LLFPINWDEPFGLVMIEAMACGTPVIAYRRGGLPEVI---QHGETGFLVDS 290
PRK09922 PRK09922
lipopolysaccharide 1,6-galactosyltransferase;
144-215 3.67e-09

lipopolysaccharide 1,6-galactosyltransferase;


Pssm-ID: 182148 [Multi-domain]  Cd Length: 359  Bit Score: 56.64  E-value: 3.67e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 955331144 144 EELSQAYASGDVFVMPSESETLGLVVLEAMSSGIPVVAA-CAGGIPDIIpvdQDGKTSYLYNPGDFEDCLSKL 215
Cdd:PRK09922 249 EVVQQKIKNVSALLLTSKFEGFPMTLLEAMSYGIPCISSdCMSGPRDII---KPGLNGELYTPGNIDEFVGKL 318
GT4_WbaZ-like cd03804
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 ...
 63-203 4.91e-08

mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbaZ in Salmonella enterica has been shown to possess mannosyltransferase activity.


Pssm-ID: 340833 [Multi-domain]  Cd Length: 356  Bit Score: 53.44  E-value: 4.91e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  63 VDSEKFHPKYRSHEMRLRLSNGEPDK--PLIVHVGRlgveksldflkRLPdARIAFVGDGPYREELEKMfeGMPAV-FTG 139
Cdd:cd03804  187 VDTDAFAPAADKEDYYLTASRLVPYKriDLAVEAFN-----------ELP-KRLVVIGDGPDLDRLRAM--ASPNVeFLG 252

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 955331144 140 MLVGEELSQAYASGDVFVMPSEsETLGLVVLEAMSSGIPVVAACAGGIPDIIpvdQDGKTSYLY 203
Cdd:cd03804  253 YQPDEVLKELLSKARAFVFAAE-EDFGIVPVEAQACGTPVIAFGKGGALETV---RPGPTGILF 312
glgA PRK00654
glycogen synthase GlgA;
78-213 1.36e-07

glycogen synthase GlgA;


Pssm-ID: 234809 [Multi-domain]  Cd Length: 466  Bit Score: 52.04  E-value: 1.36e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  78 RLRLSNgePDKPLIVHVGRLGVEKSLDFLKR-LP-----DARIAFVGDGPYreELEKMFEGMPAVFTG---MLVG--EEL 146
Cdd:PRK00654 274 RFGLPD--DDAPLFAMVSRLTEQKGLDLVLEaLPelleqGGQLVLLGTGDP--ELEEAFRALAARYPGkvgVQIGydEAL 349

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 955331144 147 S-QAYASGDVFVMPSESETLGLVVLEAMSSG-IPVVAAcAGGIPD-IIPVDQDGK--TSYL---YNPGDFEDCLS 213
Cdd:PRK00654 350 AhRIYAGADMFLMPSRFEPCGLTQLYALRYGtLPIVRR-TGGLADtVIDYNPEDGeaTGFVfddFNAEDLLRALR 423
PRK15179 PRK15179
Vi polysaccharide biosynthesis protein TviE; Provisional
 97-209 3.29e-07

Vi polysaccharide biosynthesis protein TviE; Provisional


Pssm-ID: 185101 [Multi-domain]  Cd Length: 694  Bit Score: 51.19  E-value: 3.29e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  97 LGVEKSLDFLKRLPDARIAFVGDGPYREEL----EKMFEGMPAVFTGML--VGEELSQAyasgDVFVMPSESETLGLVVL 170
Cdd:PRK15179 534 LWVEAAQRFAASHPKVRFIMVGGGPLLESVrefaQRLGMGERILFTGLSrrVGYWLTQF----NAFLLLSRFEGLPNVLI 609

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 955331144 171 EAMSSGIPVVAACAGGIPDIIpvdQDGKTSYLYNPGDFE 209
Cdd:PRK15179 610 EAQFSGVPVVTTLAGGAGEAV---QEGVTGLTLPADTVT 645
PLN00142 PLN00142
sucrose synthase
 155-242 8.67e-07

sucrose synthase


Pssm-ID: 215073 [Multi-domain]  Cd Length: 815  Bit Score: 49.98  E-value: 8.67e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 155 VFVMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIpvdQDGKTSYLYNP--GD---------FEDClsKLRPLLLNKe 223
Cdd:PLN00142 669 AFVQPALYEAFGLTVVEAMTCGLPTFATCQGGPAEII---VDGVSGFHIDPyhGDeaankiadfFEKC--KEDPSYWNK- 742

                         90       100
                 ....*....|....*....|
gi 955331144 224 lretMGKAAREEM-EKYDWK 242
Cdd:PLN00142 743 ----ISDAGLQRIyECYTWK 758
Glyco_trans_1_2 pfam13524
Glycosyl transferases group 1;
162-234 1.75e-06

Glycosyl transferases group 1;


Pssm-ID: 433281 [Multi-domain]  Cd Length: 93  Bit Score: 45.29  E-value: 1.75e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 955331144  162 SETLGLVVLEAMSSGIPVVAACAGGIPDIIPvdqDGKTSYLYNpgDFEDCLSKLRPLLLNKELRETMGKAARE 234
Cdd:pfam13524   9 PDSPNMRVFEAAACGAPLLTDRTPGLEELFE---PGEEILLYR--DPEELAEKIRYLLEHPEERRAIAAAGRE 76
PRK14098 PRK14098
starch synthase;
71-254 2.90e-06

starch synthase;


Pssm-ID: 172588 [Multi-domain]  Cd Length: 489  Bit Score: 48.19  E-value: 2.90e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  71 KYRSHEMRLRLSNGEPDKPLIVHVGRL-GVEKSLDFLKRLPDARIAFVGDGPYREELEKMFEGMPAVFTGML-VGEELS- 147
Cdd:PRK14098 293 KALLEEVGLPFDEETPLVGVIINFDDFqGAELLAESLEKLVELDIQLVICGSGDKEYEKRFQDFAEEHPEQVsVQTEFTd 372

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 148 ----QAYASGDVFVMPSESETLGLVVLEAMSSG-IPVVAACAGGIPDIIPVDQDGKTSYLYNPGDFEDCLSKLRPLLLNK 222
Cdd:PRK14098 373 affhLAIAGLDMLLMPGKIESCGMLQMFAMSYGtIPVAYAGGGIVETIEEVSEDKGSGFIFHDYTPEALVAKLGEALALY 452

                        170       180       190
                 ....*....|....*....|....*....|...
gi 955331144 223 ELRETMGKAAREEMEK-YDWKEATrkirnEQYN 254
Cdd:PRK14098 453 HDEERWEELVLEAMERdFSWKNSA-----EEYA 480
GT4_ALG2-like cd03805
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely ...
 161-244 1.21e-05

alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans.


Pssm-ID: 340834 [Multi-domain]  Cd Length: 392  Bit Score: 46.04  E-value: 1.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 161 ESETLGLVVLEAMSSGIPVVAACAGGipdiiPVD--QDGKTSYLY--NPGDFedcLSKLRPLLLNKELRETMGKAAREEM 236
Cdd:cd03805  308 SNEHFGIVPLEAMYAGKPVIACNSGG-----PLEtvVEGVTGFLCepTPEAF---AEAMLKLANDPDLADRMGAAGRKRV 379


                 ....*...
gi 955331144 237 EKYDWKEA 244
Cdd:cd03805  380 KEKFSREA 387
PRK15490 PRK15490
Vi polysaccharide biosynthesis glycosyltransferase TviE;
105-186 4.84e-05

Vi polysaccharide biosynthesis glycosyltransferase TviE;


Pssm-ID: 185387 [Multi-domain]  Cd Length: 578  Bit Score: 44.69  E-value: 4.84e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 105 FLKRLPDARIAFVGDGPYREELEKMFEGMPAVFTGMLVGEELSQAY--ASGDVFVMPSESETLGLVVLEAMSSGIPVVAA 182
Cdd:PRK15490 423 YLQHHPATRFVLVGDGDLRAEAQKRAEQLGILERILFVGASRDVGYwlQKMNVFILFSRYEGLPNVLIEAQMVGVPVIST 502


                 ....
gi 955331144 183 CAGG 186
Cdd:PRK15490 503 PAGG 506
PRK14099 PRK14099
glycogen synthase GlgA;
85-191 3.00e-04

glycogen synthase GlgA;


Pssm-ID: 237610 [Multi-domain]  Cd Length: 485  Bit Score: 42.01  E-value: 3.00e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  85 EPDKPLIVHVGRLGVEKSLDFL-KRLP-----DARIAFVGDGpyREELEKMFEGMPAVF---TGMLVG--EELS-QAYAS 152
Cdd:PRK14099 292 DPDALLLGVISRLSWQKGLDLLlEALPtllgeGAQLALLGSG--DAELEARFRAAAQAYpgqIGVVIGydEALAhLIQAG 369

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 955331144 153 GDVFVMPSESETLGLVVLEAMSSG-IPVVAAcAGGIPDII 191
Cdd:PRK14099 370 ADALLVPSRFEPCGLTQLCALRYGaVPVVAR-VGGLADTV 408
GT4_ALG11-like cd03806
alpha-1,2-mannosyltransferase ALG11 and similar proteins; This family is most closely related ...
 100-239 3.04e-04

alpha-1,2-mannosyltransferase ALG11 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG11 in yeast is involved in adding the final 1,2-linked Man to the Man5GlcNAc2-PP-Dol synthesized on the cytosolic face of the ER. The deletion analysis of ALG11 was shown to block the early steps of core biosynthesis that takes place on the cytoplasmic face of the ER and lead to a defect in the assembly of lipid-linked oligosaccharides.


Pssm-ID: 340835 [Multi-domain]  Cd Length: 419  Bit Score: 41.83  E-value: 3.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 100 EKSLDFLKRL-----PDARIAFVGDGPYREelekmfegmpavftgmlVGEELSQAYASgdVFVMpsESETLGLVVLEAMS 174
Cdd:cd03806  288 KERVEALKLLakeliLEDSVEFVVDAPYEE-----------------LKELLSTASIG--LHTM--WNEHFGIGVVEYMA 346

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 955331144 175 SG-IPVVAACAGGIPDIIPVDQDGKTSYLY-NPGDFEDCLSKLrpLLLNKELRETMGKAAREEMEKY 239
Cdd:cd03806  347 AGlIPLAHASAGPLLDIVVPWDGGPTGFLAsTPEEYAEAIEKI--LTLSEEERLQRREAARSSAERF 411
COG4641 COG4641
Spore maturation protein CgeB [Cell cycle control, cell division, chromosome partitioning];
53-234 3.94e-04

Spore maturation protein CgeB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443679 [Multi-domain]  Cd Length: 303  Bit Score: 41.07  E-value: 3.94e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  53 ANKIRLWNKGVDSEKFHPKYRSHEMRLRLS---NGEPDKPLIVHvgrlgvekslDFLKRLPDARIAFVGDGpYREELekm 129
Cdd:COG4641  112 ARRVFYLPFAADPELHRPVPPEARFRYDVAfvgNYYPDRRARLE----------ELLLAPAGLRLKIYGPG-WPKLA--- 177

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 130 fegMPAVFT--GMLVGEELSQAYASGDVFV----MPSESETLGLVVLEAMSSGIPVVAACAGGIPDiipvdqdgktsyLY 203
Cdd:COG4641  178 ---LPANVRrgGHLPGEEHPAAYASSKITLnvnrMAASPDSPTRRTFEAAACGAFLLSDPWEGLEE------------LF 242

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 955331144 204 NPG-------DFEDCLSKLRPLLLNKELRETMGKAARE 234
Cdd:COG4641  243 EPGeevlvfrDGEELAEKLRYLLADPEERRAIAEAGRR 280
Glyco_transf_4 pfam13439
Glycosyltransferase Family 4;
6-66 4.59e-04

Glycosyltransferase Family 4;


Pssm-ID: 463877 [Multi-domain]  Cd Length: 169  Bit Score: 40.21  E-value: 4.59e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 955331144    6 RYIPRYTFSWLVKPMWLIIKFLHRAADLTLVPSAAIAGDLLAARVTAANKIRLWNKGVDSE 66
Cdd:pfam13439 109 YKRLGARLSPLRRLLRRLERRLLRRADRVIAVSEAVADELRRLYGVPPEKIRVIPNGVDLE 169
PRK10307 PRK10307
colanic acid biosynthesis glycosyltransferase WcaI;
52-245 1.18e-03

colanic acid biosynthesis glycosyltransferase WcaI;


Pssm-ID: 236670 [Multi-domain]  Cd Length: 412  Bit Score: 39.96  E-value: 1.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144  52 AANKIRLWNKGVDSEKFHPKYRSHEMRLRLSNGEPDKPLIV-HVGRL----GVEKSLDFLKRL---PDARIAFVGDGPYR 123
Cdd:PRK10307 192 AAEKVIFFPNWSEVARFQPVADADVDALRAQLGLPDGKKIVlYSGNIgekqGLELVIDAARRLrdrPDLIFVICGQGGGK 271

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 124 EELEKM--FEGMPAV-FTGMLVGEELSQAYASGDVFVMPSESETLGLVV---LEAM-SSGIPVVA----------ACAgG 186
Cdd:PRK10307 272 ARLEKMaqCRGLPNVhFLPLQPYDRLPALLKMADCHLLPQKAGAADLVLpskLTNMlASGRNVVAtaepgtelgqLVE-G 350

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 955331144 187 IPDIIPvdqdgktsylynPGDFEDCLSKLRPLLLNKELRETMGKAAREEMEKYDWKEAT 245
Cdd:PRK10307 351 IGVCVE------------PESVEALVAAIAALARQALLRPKLGTVAREYAERTLDKENV 397
sucrsPsyn_pln TIGR02468
sucrose phosphate synthase/possible sucrose phosphate phosphatase, plant; Members of this ...
 155-224 2.62e-03

sucrose phosphate synthase/possible sucrose phosphate phosphatase, plant; Members of this family are sucrose-phosphate synthases of plants. This enzyme is known to exist in multigene families in several species of both monocots and dicots. The N-terminal domain is the glucosyltransferase domain. Members of this family also have a variable linker region and a C-terminal domain that resembles sucrose phosphate phosphatase (SPP) (EC 3.1.3.24) (see TIGR01485), the next and final enzyme of sucrose biosynthesis. The SPP-like domain likely serves a binding and not a catalytic function, as the reported SPP is always encoded by a distinct protein.


Pssm-ID: 274147 [Multi-domain]  Cd Length: 1050  Bit Score: 39.38  E-value: 2.62e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144   155 VFVMPSESETLGLVVLEAMSSGIPVVAACAGGIPDIIPVDQDGktsYLYNPGDFEDCLSKLRPLLLNKEL 224
Cdd:TIGR02468  574 VFINPAFIEPFGLTLIEAAAHGLPMVATKNGGPVDIHRVLDNG---LLVDPHDQQAIADALLKLVADKQL 640
PLN02949 PLN02949
transferase, transferring glycosyl groups
 163-250 5.43e-03

transferase, transferring glycosyl groups


Pssm-ID: 215511 [Multi-domain]  Cd Length: 463  Bit Score: 38.18  E-value: 5.43e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955331144 163 ETLGLVVLEAMSSG-IPVVAACAGGIPDIIpVDQDG-KTSYL-YNPGDFEDCLSKLrpLLLNKELRETMGKAAREEMEKY 239
Cdd:PLN02949 365 EHFGISVVEYMAAGaVPIAHNSAGPKMDIV-LDEDGqQTGFLaTTVEEYADAILEV--LRMRETERLEIAAAARKRANRF 441

                         90
                 ....*....|....*...
gi 955331144 240 -------DWKEATRKIRN 250
Cdd:PLN02949 442 seqrfneDFKDAIRPILN 459
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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