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Conserved domains on  [gi|953841650|ref|XP_014588678|]
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pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 [Equus caballus]

Protein Classification

phytoene desaturase family protein( domain architecture ID 11440907)

phytoene desaturase family protein is an NAD(P)/FAD-dependent oxidoreductase that catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant; similar to phytoene desaturase, which converts phytoene into 3,4-didehydrolycopene via several intermediates by introducing up to five double bonds into phytoene

CATH:  3.50.50.60
EC:  1.-.-.-
Gene Ontology:  GO:0016491|GO:0009055|GO:0016117|GO:0016116
SCOP:  4000128|3000055

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 35-580 3.92e-115

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 351.07  E-value: 3.92e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  35 YDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEiIPGFKFSRASYLLSLLRP--QIYTDLELKKHgLRLH 112
Cdd:COG1233    4 YDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTPGGRARTFE-RPGFRFDVGPSVLTMPGVleRLFRELGLEDY-LELV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650 113 LRNPySFTPMLEEGtgskvpRSLLLGTDMVENQKHISQFSPQDAQAFPRYEAFMNRLALAIDPLLDTAPvdmeafqrgsl 192
Cdd:COG1233   82 PLDP-AYRVPFPDG------RALDLPRDLERTAAELERLFPGDAEAYRRFLAELRRLYDALLEDLLYRP----------- 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650 193 lqrlksLSTLKPLLQAgrilgAQLPEYYQVLTAPITKVLDQWFESEPLKATLATdavIGAMTSPHTPGSGYVLLHHVMGg 272
Cdd:COG1233  144 ------LLSLRDLLRP-----LALARLLRLLLRSLRDLLRRYFKDPRLRALLAG---QALYLGLSPDRTPALYALIAYL- 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650 273 leGMQGAWGYVQGGMGALSAAIASSAAAHGASIFTEKTVAKVQVsSGGHVQGVVLQDGSEVRSKVVLSNASPQITFLKLT 352
Cdd:COG1233  209 --EYAGGVWYPKGGMGALADALARLAEELGGEIRTGAEVERILV-EGGRATGVRLADGEEIRADAVVSNADPAHTYLRLL 285

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650 353 PQEWLPEEFVERISQLDTRSPVTKINVAVDR-LPDflaapsapggrpLPHHQcsIHLNcEDtllLHQAFEDAMGGLPSHR 431
Cdd:COG1233  286 GEEALPARYRRRLERFRYSPSAFKLYLGLDGpLPG------------LAHHT--IHLS-ED---YEAAFDDIFRGRLPED 347

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650 432 PMIELCIPSSLDPTLAPPGCHVISLFTQyTPYTLagGKVWDEqERNAYADKVFDCIEAYAPGFKGSVLGRDILTPPDLER 511
Cdd:COG1233  348 PSLYVSIPSLTDPSLAPEGKHTLWVLVP-VPYGL--EDAWDE-LKEEYAERILARLERYAPGLRDRIVAREVLTPLDFER 423

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 953841650 512 IFGLPGGNIFHCAMALDQLYFARPvplhSGYRSPLQGLYLCGSGAHPGGGVMGAA--GRNAAHMVFRDLKS 580
Cdd:COG1233  424 YLNLVGGAIYGGAHTLDQSAFFRP----SNYRTPIPGLYLVGASTHPGGGVPGVLisGRLAARRILKDLKR 490
FAD_binding_2 super family cl46878
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 2-61 3.93e-03

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


The actual alignment was detected with superfamily member PLN00128:

Pssm-ID: 481218 [Multi-domain]  Cd Length: 635  Bit Score: 40.23  E-value: 3.93e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 953841650   2 AASGRGLCRAVGASPRPAWRRAHWEARGH-----LKPEYDAVVIGAGHNGLVAAAYLQRLGVNTA 61
Cdd:PLN00128  13 LASSSASSSLASASLRTALSRFFSTGGGRssytiVDHTYDAVVVGAGGAGLRAAIGLSEHGFNTA 77
 
Name Accession Description Interval E-value
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 35-580 3.92e-115

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 351.07  E-value: 3.92e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  35 YDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEiIPGFKFSRASYLLSLLRP--QIYTDLELKKHgLRLH 112
Cdd:COG1233    4 YDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTPGGRARTFE-RPGFRFDVGPSVLTMPGVleRLFRELGLEDY-LELV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650 113 LRNPySFTPMLEEGtgskvpRSLLLGTDMVENQKHISQFSPQDAQAFPRYEAFMNRLALAIDPLLDTAPvdmeafqrgsl 192
Cdd:COG1233   82 PLDP-AYRVPFPDG------RALDLPRDLERTAAELERLFPGDAEAYRRFLAELRRLYDALLEDLLYRP----------- 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650 193 lqrlksLSTLKPLLQAgrilgAQLPEYYQVLTAPITKVLDQWFESEPLKATLATdavIGAMTSPHTPGSGYVLLHHVMGg 272
Cdd:COG1233  144 ------LLSLRDLLRP-----LALARLLRLLLRSLRDLLRRYFKDPRLRALLAG---QALYLGLSPDRTPALYALIAYL- 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650 273 leGMQGAWGYVQGGMGALSAAIASSAAAHGASIFTEKTVAKVQVsSGGHVQGVVLQDGSEVRSKVVLSNASPQITFLKLT 352
Cdd:COG1233  209 --EYAGGVWYPKGGMGALADALARLAEELGGEIRTGAEVERILV-EGGRATGVRLADGEEIRADAVVSNADPAHTYLRLL 285

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650 353 PQEWLPEEFVERISQLDTRSPVTKINVAVDR-LPDflaapsapggrpLPHHQcsIHLNcEDtllLHQAFEDAMGGLPSHR 431
Cdd:COG1233  286 GEEALPARYRRRLERFRYSPSAFKLYLGLDGpLPG------------LAHHT--IHLS-ED---YEAAFDDIFRGRLPED 347

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650 432 PMIELCIPSSLDPTLAPPGCHVISLFTQyTPYTLagGKVWDEqERNAYADKVFDCIEAYAPGFKGSVLGRDILTPPDLER 511
Cdd:COG1233  348 PSLYVSIPSLTDPSLAPEGKHTLWVLVP-VPYGL--EDAWDE-LKEEYAERILARLERYAPGLRDRIVAREVLTPLDFER 423

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 953841650 512 IFGLPGGNIFHCAMALDQLYFARPvplhSGYRSPLQGLYLCGSGAHPGGGVMGAA--GRNAAHMVFRDLKS 580
Cdd:COG1233  424 YLNLVGGAIYGGAHTLDQSAFFRP----SNYRTPIPGLYLVGASTHPGGGVPGVLisGRLAARRILKDLKR 490
crtI_fam TIGR02734
phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two ...
 37-580 1.12e-28

phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 274273 [Multi-domain]  Cd Length: 495  Bit Score: 119.69  E-value: 1.12e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650   37 AVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEiIPGFKFSrasyllslLRPQIYTDLELKKHGLRL---HL 113
Cdd:TIGR02734   1 AVVIGAGFGGLALAIRLAAAGIPVTVVEQRDKPGGRAGVLE-DDGFRFD--------TGPTVITMPEALEELFALagrDL 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  114 RNPYSFTPM-----LEEGTGSKVPRSlllgTDMVENQKHISQFSPQDAQAFPRYEAFMNRL-ALAIDPLLDTAPVDMEAF 187
Cdd:TIGR02734  72 ADYVELVPLdpfyrLCWEDGSQLDVD----NDQEELEAQIARFNPGDVAGYRRFLDYAERVyREGYRKLGYVPFLSPRDL 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  188 QRGSLLQRLKslstlkplLQAGRILGAQLPEYyqvltapitkvldqwFESEPLKATLATDAV-IGamTSPHTPGSGYVLL 266
Cdd:TIGR02734 148 LRADAPQLLA--------LLAWRSLYSKVARF---------------FSDERLRQAFSFHALfLG--GNPFRTPSIYALI 202

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  267 HHvmggLEGMQGAWgYVQGGMGALSAAIASSAAAHGASIFTEKTVAKVqVSSGGHVQGVVLQDGSEVRSKVVLSNASPQI 346
Cdd:TIGR02734 203 SA----LEREWGVW-FPRGGTGALVAAMAKLAEDLGGELRLNAEVIRI-ETEGGRATAVHLADGERLDADAVVSNADLHH 276

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  347 TFLKLTPQewlPEEFVERISQLDTRSP-------VTKINVAVDRLPDflaapsapggrpLPHHqcSIHLNCEDTLLLHQA 419
Cdd:TIGR02734 277 TYRRLLPN---HPRRRYPAARLSRKRPspslfvlYFGLLGVDGHWPQ------------LAHH--TLCFGPRYKELFDEI 339

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  420 FEdamGGLPSHRPMIELCIPSSLDPTLAPPGCHviSLFTQY-TPYTLAGGKVWDeQERNAYADKVFDCIEAYA-PGFKGS 497
Cdd:TIGR02734 340 FR---KGRLAEDPSLYLHRPTVTDPSLAPPGCE--SLYVLApVPHLGTADVDWS-VEGPRYRDRILAYLEERAiPGLRDR 413

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  498 VLGRDILTPPDLERIFGLPGGNIFHCAMALDQLYFARPVPLHSGyrspLQGLYLCGSGAHPGGGVMG--AAGRNAAHMVF 575
Cdd:TIGR02734 414 IVVERTFTPADFRDRYNAWLGSAFSLEHTLTQSAWFRPHNRDRK----IDNLYLVGAGTHPGAGVPGvlGSAKATAKLML 489


                  ....*
gi 953841650  576 RDLKS 580
Cdd:TIGR02734 490 GDLAP 494
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
39-99 9.01e-10

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 54.84  E-value: 9.01e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 953841650   39 VIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEiIPGFKFSR-ASYLLSLLRPQIY 99
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNAYSYR-VPGYVFDYgAHIFHGSDEPNVR 61
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 39-83 1.90e-06

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 50.56  E-value: 1.90e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 953841650  39 VIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGaaVTEEIIPGFK 83
Cdd:PRK11749 145 VIGAGPAGLTAAHRLARKGYDVTIFEARDKAGG--LLRYGIPEFR 187
PLN00128 PLN00128
Succinate dehydrogenase [ubiquinone] flavoprotein subunit
 2-61 3.93e-03

Succinate dehydrogenase [ubiquinone] flavoprotein subunit


Pssm-ID: 177739 [Multi-domain]  Cd Length: 635  Bit Score: 40.23  E-value: 3.93e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 953841650   2 AASGRGLCRAVGASPRPAWRRAHWEARGH-----LKPEYDAVVIGAGHNGLVAAAYLQRLGVNTA 61
Cdd:PLN00128  13 LASSSASSSLASASLRTALSRFFSTGGGRssytiVDHTYDAVVVGAGGAGLRAAIGLSEHGFNTA 77
 
Name Accession Description Interval E-value
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 35-580 3.92e-115

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 351.07  E-value: 3.92e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  35 YDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEiIPGFKFSRASYLLSLLRP--QIYTDLELKKHgLRLH 112
Cdd:COG1233    4 YDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTPGGRARTFE-RPGFRFDVGPSVLTMPGVleRLFRELGLEDY-LELV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650 113 LRNPySFTPMLEEGtgskvpRSLLLGTDMVENQKHISQFSPQDAQAFPRYEAFMNRLALAIDPLLDTAPvdmeafqrgsl 192
Cdd:COG1233   82 PLDP-AYRVPFPDG------RALDLPRDLERTAAELERLFPGDAEAYRRFLAELRRLYDALLEDLLYRP----------- 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650 193 lqrlksLSTLKPLLQAgrilgAQLPEYYQVLTAPITKVLDQWFESEPLKATLATdavIGAMTSPHTPGSGYVLLHHVMGg 272
Cdd:COG1233  144 ------LLSLRDLLRP-----LALARLLRLLLRSLRDLLRRYFKDPRLRALLAG---QALYLGLSPDRTPALYALIAYL- 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650 273 leGMQGAWGYVQGGMGALSAAIASSAAAHGASIFTEKTVAKVQVsSGGHVQGVVLQDGSEVRSKVVLSNASPQITFLKLT 352
Cdd:COG1233  209 --EYAGGVWYPKGGMGALADALARLAEELGGEIRTGAEVERILV-EGGRATGVRLADGEEIRADAVVSNADPAHTYLRLL 285

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650 353 PQEWLPEEFVERISQLDTRSPVTKINVAVDR-LPDflaapsapggrpLPHHQcsIHLNcEDtllLHQAFEDAMGGLPSHR 431
Cdd:COG1233  286 GEEALPARYRRRLERFRYSPSAFKLYLGLDGpLPG------------LAHHT--IHLS-ED---YEAAFDDIFRGRLPED 347

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650 432 PMIELCIPSSLDPTLAPPGCHVISLFTQyTPYTLagGKVWDEqERNAYADKVFDCIEAYAPGFKGSVLGRDILTPPDLER 511
Cdd:COG1233  348 PSLYVSIPSLTDPSLAPEGKHTLWVLVP-VPYGL--EDAWDE-LKEEYAERILARLERYAPGLRDRIVAREVLTPLDFER 423

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 953841650 512 IFGLPGGNIFHCAMALDQLYFARPvplhSGYRSPLQGLYLCGSGAHPGGGVMGAA--GRNAAHMVFRDLKS 580
Cdd:COG1233  424 YLNLVGGAIYGGAHTLDQSAFFRP----SNYRTPIPGLYLVGASTHPGGGVPGVLisGRLAARRILKDLKR 490
crtI_fam TIGR02734
phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two ...
 37-580 1.12e-28

phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 274273 [Multi-domain]  Cd Length: 495  Bit Score: 119.69  E-value: 1.12e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650   37 AVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEiIPGFKFSrasyllslLRPQIYTDLELKKHGLRL---HL 113
Cdd:TIGR02734   1 AVVIGAGFGGLALAIRLAAAGIPVTVVEQRDKPGGRAGVLE-DDGFRFD--------TGPTVITMPEALEELFALagrDL 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  114 RNPYSFTPM-----LEEGTGSKVPRSlllgTDMVENQKHISQFSPQDAQAFPRYEAFMNRL-ALAIDPLLDTAPVDMEAF 187
Cdd:TIGR02734  72 ADYVELVPLdpfyrLCWEDGSQLDVD----NDQEELEAQIARFNPGDVAGYRRFLDYAERVyREGYRKLGYVPFLSPRDL 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  188 QRGSLLQRLKslstlkplLQAGRILGAQLPEYyqvltapitkvldqwFESEPLKATLATDAV-IGamTSPHTPGSGYVLL 266
Cdd:TIGR02734 148 LRADAPQLLA--------LLAWRSLYSKVARF---------------FSDERLRQAFSFHALfLG--GNPFRTPSIYALI 202

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  267 HHvmggLEGMQGAWgYVQGGMGALSAAIASSAAAHGASIFTEKTVAKVqVSSGGHVQGVVLQDGSEVRSKVVLSNASPQI 346
Cdd:TIGR02734 203 SA----LEREWGVW-FPRGGTGALVAAMAKLAEDLGGELRLNAEVIRI-ETEGGRATAVHLADGERLDADAVVSNADLHH 276

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  347 TFLKLTPQewlPEEFVERISQLDTRSP-------VTKINVAVDRLPDflaapsapggrpLPHHqcSIHLNCEDTLLLHQA 419
Cdd:TIGR02734 277 TYRRLLPN---HPRRRYPAARLSRKRPspslfvlYFGLLGVDGHWPQ------------LAHH--TLCFGPRYKELFDEI 339

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  420 FEdamGGLPSHRPMIELCIPSSLDPTLAPPGCHviSLFTQY-TPYTLAGGKVWDeQERNAYADKVFDCIEAYA-PGFKGS 497
Cdd:TIGR02734 340 FR---KGRLAEDPSLYLHRPTVTDPSLAPPGCE--SLYVLApVPHLGTADVDWS-VEGPRYRDRILAYLEERAiPGLRDR 413

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  498 VLGRDILTPPDLERIFGLPGGNIFHCAMALDQLYFARPVPLHSGyrspLQGLYLCGSGAHPGGGVMG--AAGRNAAHMVF 575
Cdd:TIGR02734 414 IVVERTFTPADFRDRYNAWLGSAFSLEHTLTQSAWFRPHNRDRK----IDNLYLVGAGTHPGAGVPGvlGSAKATAKLML 489


                  ....*
gi 953841650  576 RDLKS 580
Cdd:TIGR02734 490 GDLAP 494
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
39-99 9.01e-10

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 54.84  E-value: 9.01e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 953841650   39 VIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEiIPGFKFSR-ASYLLSLLRPQIY 99
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNAYSYR-VPGYVFDYgAHIFHGSDEPNVR 61
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 46-571 1.72e-08

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 57.12  E-value: 1.72e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650   46 GLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEiIPGFKFSRASYLLSLLRPQIYTdlELKKHGLRLHLRNPYSFTPMLEE 125
Cdd:pfam01593   3 GLAAARELLRAGHDVTVLEARDRVGGRIRTVR-DDGFLIELGAMWFHGAQPPLLA--LLKELGLEDRLVLPDPAPFYTVL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  126 GTGSKVPRSLLlgtdmvenqkhisQFSPQDAQAFPRYEAFMN---RLALAIDPLLdTAPVDMEAFQRGSLLQRLKSLStl 202
Cdd:pfam01593  80 FAGGRRYPGDF-------------RRVPAGWEGLLEFGRLLSipeKLRLGLAALA-SDALDEFDLDDFSLAESLLFLG-- 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  203 kpllqaGRILGAQlpeyyqvltapitKVLDQWFESEPLKATLATDAVIGAMTSPHTPGSGYVLLHHVMGGLEGMQGAwgy 282
Cdd:pfam01593 144 ------RRGPGDV-------------EVWDRLIDPELFAALPFASGAFAGDPSELSAGLALPLLWALLGEGGSLLLP--- 201

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  283 vQGGMGalSAAIASSAAAHGASIFTEKTVAKVQVSSGGHvqGVVLQDGSEVRSKVVLSnASPQITFLKLTPQEWLPEEFV 362
Cdd:pfam01593 202 -RGGLG--ALPDALAAQLLGGDVRLNTRVRSIDREGDGV--TVTLTDGEVIEADAVIV-TVPLGVLKRILFTPPLPPEKA 275

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  363 ERISQLDTRsPVTKINVAVDRlpdflaapsapggRPLPHHQCSiHLNCEDTLLLHQAFEdamgglpshrpmielcipSSL 442
Cdd:pfam01593 276 RAIRNLGYG-PVNKVHLEFDR-------------KFWPDLGLL-GLLSELLTGLGTAFS------------------WLT 322

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650  443 DPTLAPPGCHVISLftqytPYTLAGGKVW-----DEQERnayADKVFDCIEayapgfkgSVLGRDILTPPDLERiFGLPG 517
Cdd:pfam01593 323 FPNRAPPGKGLLLL-----VYVGPGDRAReleglSDEEL---LQAVLRDLR--------KLFGEEAPEPLRVLV-SDWHT 385

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 953841650  518 GNIFHCAMALDQlYFARPVPLHSGYRSPLQGLYLCGSGAHPG--GGVMGA--AGRNAA 571
Cdd:pfam01593 386 DPWPRGSYSLPQ-YGPGHDDYRPLARTPDPGLFFAGEHTSTGypGTVEGAieSGRRAA 442
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 33-72 3.48e-08

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 56.02  E-value: 3.48e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 953841650  33 PEYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGA 72
Cdd:COG2072    5 EHVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGT 44
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 39-86 1.64e-06

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 50.52  E-value: 1.64e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 953841650  39 VIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGaaVTEEIIPGFKFSR 86
Cdd:COG0493  126 VVGSGPAGLAAAYQLARAGHEVTVFEALDKPGG--LLRYGIPEFRLPK 171
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 39-83 1.90e-06

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 50.56  E-value: 1.90e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 953841650  39 VIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGaaVTEEIIPGFK 83
Cdd:PRK11749 145 VIGAGPAGLTAAHRLARKGYDVTIFEARDKAGG--LLRYGIPEFR 187
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
35-82 2.53e-06

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 49.35  E-value: 2.53e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 953841650  35 YDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHViGG-AAVTEEI--IPGF 82
Cdd:COG0492    1 YDVVIIGAGPAGLTAAIYAARAGLKTLVIEGGEP-GGqLATTKEIenYPGF 50
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 35-78 3.33e-06

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 49.83  E-value: 3.33e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 953841650  35 YDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEI 78
Cdd:COG1232    2 KRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVGGLIRTVEV 45
PRK06370 PRK06370
FAD-containing oxidoreductase;
33-74 4.59e-06

FAD-containing oxidoreductase;


Pssm-ID: 235787 [Multi-domain]  Cd Length: 463  Bit Score: 49.43  E-value: 4.59e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 953841650  33 PEYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHViGGAAV 74
Cdd:PRK06370   4 QRYDAIVIGAGQAGPPLAARAAGLGMKVALIERGLL-GGTCV 44
PLN02976 PLN02976
amine oxidase
 38-135 2.80e-05

amine oxidase


Pssm-ID: 215527 [Multi-domain]  Cd Length: 1713  Bit Score: 47.17  E-value: 2.80e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650   38 VVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEE------------IIPGFKFSRASYLL----SLLRPQIytd 101
Cdd:PLN02976  697 IVVGAGPAGLTAARHLQRQGFSVTVLEARSRIGGRVYTDRsslsvpvdlgasIITGVEADVATERRpdpsSLICAQL--- 773

                          90       100       110
                  ....*....|....*....|....*....|....
gi 953841650  102 lelkkhGLRLHLRNpySFTPMLEEGTGSKVPRSL 135
Cdd:PLN02976  774 ------GLELTVLN--SDCPLYDVVTGEKVPADL 799
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 27-83 4.93e-05

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 45.93  E-value: 4.93e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 953841650  27 ARGHLKPEYDAV-------VIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGaaVTEEIIPGFK 83
Cdd:PRK12810 129 EEGWVKPDPPVKrtgkkvaVVGSGPAGLAAADQLARAGHKVTVFERADRIGG--LLRYGIPDFK 190
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 34-80 8.51e-05

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 45.08  E-value: 8.51e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 953841650  34 EYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHViGGAAVTEEIIP 80
Cdd:COG1249    3 DYDLVVIGAGPGGYVAAIRAAQLGLKVALVEKGRL-GGTCLNVGCIP 48
PRK12775 PRK12775
putative trifunctional 2-polyprenylphenol hydroxylase/glutamate synthase subunit beta/ferritin ...
 39-86 8.53e-05

putative trifunctional 2-polyprenylphenol hydroxylase/glutamate synthase subunit beta/ferritin domain-containing protein; Provisional


Pssm-ID: 183738 [Multi-domain]  Cd Length: 1006  Bit Score: 45.70  E-value: 8.53e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 953841650   39 VIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGaaVTEEIIPGFKFSR 86
Cdd:PRK12775  435 ICGSGPAGLAAAADLVKYGVDVTVYEALHVVGG--VLQYGIPSFRLPR 480
PLN02576 PLN02576
protoporphyrinogen oxidase
 26-71 9.57e-05

protoporphyrinogen oxidase


Pssm-ID: 215314 [Multi-domain]  Cd Length: 496  Bit Score: 45.00  E-value: 9.57e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 953841650  26 EARGHLKPEYDAVVIGAGHNGLVAAAYLQ-RLGVNTAVFERRHVIGG 71
Cdd:PLN02576   4 AEGSAAASSKDVAVVGAGVSGLAAAYALAsKHGVNVLVTEARDRVGG 50
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 34-74 1.02e-04

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 44.82  E-value: 1.02e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 953841650  34 EYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAV 74
Cdd:COG1053    3 EYDVVVVGSGGAGLRAALEAAEAGLKVLVLEKVPPRGGHTA 43
PRK05249 PRK05249
Si-specific NAD(P)(+) transhydrogenase;
34-74 1.75e-04

Si-specific NAD(P)(+) transhydrogenase;


Pssm-ID: 235373 [Multi-domain]  Cd Length: 461  Bit Score: 44.38  E-value: 1.75e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 953841650  34 EYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAV 74
Cdd:PRK05249   5 DYDLVVIGSGPAGEGAAMQAAKLGKRVAVIERYRNVGGGCT 45
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 36-73 1.87e-04

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 43.93  E-value: 1.87e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 953841650   36 DAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAA 73
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGDDPGSGA 38
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 33-66 2.43e-04

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 43.39  E-value: 2.43e-04
                         10        20        30
                 ....*....|....*....|....*....|....
gi 953841650  33 PEYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERR 66
Cdd:COG0654    2 MRTDVLIVGGGPAGLALALALARAGIRVTVVERA 35
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
30-71 3.22e-04

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 43.37  E-value: 3.22e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 953841650  30 HLKPEYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGG 71
Cdd:COG1231    3 RRARGKDVVIVGAGLAGLAAARELRKAGLDVTVLEARDRVGG 44
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
34-72 3.24e-04

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 43.36  E-value: 3.24e-04
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 953841650  34 EYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGA 72
Cdd:COG0665    2 TADVVVIGGGIAGLSTAYHLARRGLDVTVLERGRPGSGA 40
Thi4 pfam01946
Thi4 family; This family includes Swiss:P32318 a putative thiamine biosynthetic enzyme.
 34-73 5.89e-04

Thi4 family; This family includes Swiss:P32318 a putative thiamine biosynthetic enzyme.


Pssm-ID: 460393  Cd Length: 232  Bit Score: 41.69  E-value: 5.89e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 953841650   34 EYDAVVIGAGHNGLVAAAYL-QRLGVNTAVFERRHVIGGAA 73
Cdd:pfam01946  17 ESDVVIVGAGSSGLTAAYYLaKNRGLKVAIIERSVSPGGGA 57
PRK10157 PRK10157
putative oxidoreductase FixC; Provisional
 35-82 8.60e-04

putative oxidoreductase FixC; Provisional


Pssm-ID: 182273 [Multi-domain]  Cd Length: 428  Bit Score: 42.21  E-value: 8.60e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 953841650  35 YDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVT---------EEIIPGF 82
Cdd:PRK10157   6 FDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKNVTggrlyahslEHIIPGF 62
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 6-65 8.83e-04

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 42.14  E-value: 8.83e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 953841650   6 RGLCRAVGASPRPAWRRAHWEARGHLKPEYDAVVIGAGHNGLVAAAYLQRLGVNTAVFER 65
Cdd:PRK01747 232 REMLVGELEQTLPAPLAAPWFARPGSPKARDAAIIGGGIAGAALALALARRGWQVTLYEA 291
PRK10015 PRK10015
oxidoreductase; Provisional
 34-82 1.48e-03

oxidoreductase; Provisional


Pssm-ID: 182194 [Multi-domain]  Cd Length: 429  Bit Score: 41.12  E-value: 1.48e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 953841650  34 EYDAVVIGAGHNGLVAAAYLQRLGVNTAVFER------RHVIGG---AAVTEEIIPGF 82
Cdd:PRK10015   5 KFDAIVVGAGVAGSVAALVMARAGLDVLVIERgdsagcKNMTGGrlyAHTLEAIIPGF 62
GIDA pfam01134
Glucose inhibited division protein A;
36-63 2.29e-03

Glucose inhibited division protein A;


Pssm-ID: 250388 [Multi-domain]  Cd Length: 391  Bit Score: 40.61  E-value: 2.29e-03
                          10        20
                  ....*....|....*....|....*...
gi 953841650   36 DAVVIGAGHNGLVAAAYLQRLGVNTAVF 63
Cdd:pfam01134   1 DVIVIGGGHAGCEAALAAARMGAKVLLI 28
PRK06416 PRK06416
dihydrolipoamide dehydrogenase; Reviewed
 34-71 2.62e-03

dihydrolipoamide dehydrogenase; Reviewed


Pssm-ID: 235798 [Multi-domain]  Cd Length: 462  Bit Score: 40.51  E-value: 2.62e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 953841650  34 EYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHvIGG 71
Cdd:PRK06416   4 EYDVIVIGAGPGGYVAAIRAAQLGLKVAIVEKEK-LGG 40
PRK07208 PRK07208
hypothetical protein; Provisional
 36-77 2.75e-03

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 40.64  E-value: 2.75e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 953841650  36 DAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEE 77
Cdd:PRK07208   6 SVVIIGAGPAGLTAAYELLKRGYPVTVLEADPVVGGISRTVT 47
PRK06753 PRK06753
hypothetical protein; Provisional
 39-69 3.32e-03

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 40.06  E-value: 3.32e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 953841650  39 VIGAGHNGLVAAAYLQRLGVNTAVFERRHVI 69
Cdd:PRK06753   5 IIGAGIGGLTAAALLQEQGHEVKVFEKNESV 35
PLN00128 PLN00128
Succinate dehydrogenase [ubiquinone] flavoprotein subunit
 2-61 3.93e-03

Succinate dehydrogenase [ubiquinone] flavoprotein subunit


Pssm-ID: 177739 [Multi-domain]  Cd Length: 635  Bit Score: 40.23  E-value: 3.93e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 953841650   2 AASGRGLCRAVGASPRPAWRRAHWEARGH-----LKPEYDAVVIGAGHNGLVAAAYLQRLGVNTA 61
Cdd:PLN00128  13 LASSSASSSLASASLRTALSRFFSTGGGRssytiVDHTYDAVVVGAGGAGLRAAIGLSEHGFNTA 77
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 35-66 4.20e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 39.61  E-value: 4.20e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 953841650   35 YDAVVIGAGHNGLVAAAYLQRLGVNTAVFERR 66
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIEDE 32
PRK06481 PRK06481
flavocytochrome c;
31-71 4.82e-03

flavocytochrome c;


Pssm-ID: 180584 [Multi-domain]  Cd Length: 506  Bit Score: 39.82  E-value: 4.82e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 953841650  31 LKPEYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGG 71
Cdd:PRK06481  58 LKDKYDIVIVGAGGAGMSAAIEAKDAGMNPVILEKMPVAGG 98
PRK12844 PRK12844
3-ketosteroid-delta-1-dehydrogenase; Reviewed
 34-72 5.06e-03

3-ketosteroid-delta-1-dehydrogenase; Reviewed


Pssm-ID: 183787 [Multi-domain]  Cd Length: 557  Bit Score: 39.74  E-value: 5.06e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 953841650  34 EYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGA 72
Cdd:PRK12844   6 TYDVVVVGSGGGGMCAALAAADSGLEPLIVEKQDKVGGS 44
PRK07233 PRK07233
hypothetical protein; Provisional
 38-73 5.12e-03

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 39.48  E-value: 5.12e-03
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 953841650  38 VVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAA 73
Cdd:PRK07233   3 AIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGLA 38
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 34-65 6.68e-03

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 39.39  E-value: 6.68e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 953841650  34 EYDAVVIGAGHNGLVAAAYLQRLGVNTAVFER 65
Cdd:PRK06292   3 KYDVIVIGAGPAGYVAARRAAKLGKKVALIEK 34
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 37-113 6.78e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 35.64  E-value: 6.78e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 953841650   37 AVVIGAGHNGLVAAAYLQRLGVNTAVFERRhviggaavtEEIIPGFKFSRASYLLSllrpqiytdlELKKHGLRLHL 113
Cdd:pfam00070   2 VVVVGGGYIGLELAGALARLGSKVTVVERR---------DRLLPGFDPEIAKILQE----------KLEKNGIEFLL 59
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 36-74 8.80e-03

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 38.81  E-value: 8.80e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 953841650   36 DAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAV 74
Cdd:pfam00890   1 DVLVIGGGLAGLAAALAAAEAGLKVAVVEKGQPFGGATA 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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