NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|927376739|ref|XP_013934220|]
View 

1,3-beta-glucanosyltransferase GAS3 [Ogataea parapolymorpha DL-1]

Protein Classification

glycoside hydrolase family protein( domain architecture ID 581038)

glycoside hydrolase family protein may catalyze the hydrolysis of glycosidic bonds in complex sugars

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Glyco_hydro super family cl23725
Glycosyl hydrolases; A functionally diverse superfamily containing glycosyl hydrolase families ...
17-344 1.32e-138

Glycosyl hydrolases; A functionally diverse superfamily containing glycosyl hydrolase families 1,5,10,17,44,72, and others.


The actual alignment was detected with superfamily member pfam03198:

Pssm-ID: 474034 [Multi-domain]  Cd Length: 315  Bit Score: 401.75  E-value: 1.32e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927376739   17 TSAMIPIEIIGNRFIKPavdarDAGEVFFVTGVDYQPGGSSgyQDSNPTDVLSDAEACYRDAYVLQNLGskVNVIRVYTV 96
Cdd:pfam03198   6 FAATPPIEIKGNKFFDS-----KNGEQFYIKGVDYQPGGSS--ENSTLVDPLADADVCKRDIPYFKELG--INTIRVYAV 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927376739   97 NPELNHDECMSIFNSAGIYVMIDVNSPlsGESLDRYNPSQSYTYSYMERVFKMVDAFKNYPNLLGFFSGNEVINDAKSAG 176
Cdd:pfam03198  77 DPSLNHDECMKALSDAGIYVILDLNTP--KESINRADPAGSYNVDYLERYFAVIDAFKNYTNVLGFFAGNEVTNDASNTD 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927376739  177 vDPKYLRAVQRDIKQYIENNANRTIPVGYSAADVLEdgLREVTLEYMLCsidGDEDdlSKSDFFGINSYEWCsGVSDWAS 256
Cdd:pfam03198 155 -ASPYVKAAIRDMKQYISKHKYRTIPVGYSAADDAD--TRVQLADYFAC---GDDD--ERADFFGINMYEWC-GYSSFKT 225
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927376739  257 SGYGELNKTISNSTIPVFFSEYGCITKTPRTFDEVSEGVYGGLVNTLSGGLIYEYSTEANDYGLVEIASNGSVTIKKDYD 336
Cdd:pfam03198 226 SGYDDRTKEFENYSIPVFFSEYGCNKVTPRPFTEVSALYSSDMTSVFSGGLVYEYSEEANNYGLVSIDGDDVVTTLADFN 305

                  ....*...
gi 927376739  337 NLKSQLEN 344
Cdd:pfam03198 306 NLKSEYAK 313
 
Name Accession Description Interval E-value
Glyco_hydro_72 pfam03198
Glucanosyltransferase; This is a family of glycosylphosphatidylinositol-anchored beta(1-3) ...
17-344 1.32e-138

Glucanosyltransferase; This is a family of glycosylphosphatidylinositol-anchored beta(1-3)glucanosyltransferases. The active site residues in the Aspergillus fumigatus example Swiss:B0XT72 are the two glutamate residues at 160 and 261.


Pssm-ID: 397351 [Multi-domain]  Cd Length: 315  Bit Score: 401.75  E-value: 1.32e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927376739   17 TSAMIPIEIIGNRFIKPavdarDAGEVFFVTGVDYQPGGSSgyQDSNPTDVLSDAEACYRDAYVLQNLGskVNVIRVYTV 96
Cdd:pfam03198   6 FAATPPIEIKGNKFFDS-----KNGEQFYIKGVDYQPGGSS--ENSTLVDPLADADVCKRDIPYFKELG--INTIRVYAV 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927376739   97 NPELNHDECMSIFNSAGIYVMIDVNSPlsGESLDRYNPSQSYTYSYMERVFKMVDAFKNYPNLLGFFSGNEVINDAKSAG 176
Cdd:pfam03198  77 DPSLNHDECMKALSDAGIYVILDLNTP--KESINRADPAGSYNVDYLERYFAVIDAFKNYTNVLGFFAGNEVTNDASNTD 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927376739  177 vDPKYLRAVQRDIKQYIENNANRTIPVGYSAADVLEdgLREVTLEYMLCsidGDEDdlSKSDFFGINSYEWCsGVSDWAS 256
Cdd:pfam03198 155 -ASPYVKAAIRDMKQYISKHKYRTIPVGYSAADDAD--TRVQLADYFAC---GDDD--ERADFFGINMYEWC-GYSSFKT 225
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927376739  257 SGYGELNKTISNSTIPVFFSEYGCITKTPRTFDEVSEGVYGGLVNTLSGGLIYEYSTEANDYGLVEIASNGSVTIKKDYD 336
Cdd:pfam03198 226 SGYDDRTKEFENYSIPVFFSEYGCNKVTPRPFTEVSALYSSDMTSVFSGGLVYEYSEEANNYGLVSIDGDDVVTTLADFN 305

                  ....*...
gi 927376739  337 NLKSQLEN 344
Cdd:pfam03198 306 NLKSEYAK 313
BglC COG2730
Aryl-phospho-beta-D-glucosidase BglC, GH1 family [Carbohydrate transport and metabolism];
89-213 4.85e-04

Aryl-phospho-beta-D-glucosidase BglC, GH1 family [Carbohydrate transport and metabolism];


Pssm-ID: 442036 [Multi-domain]  Cd Length: 295  Bit Score: 41.95  E-value: 4.85e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927376739  89 NVIRV-------------YTVNPE-LNH-DECMSIFNSAGIYVMIDVNSPLSGesldrYNPSQSYTYSYMERVFKMV-DA 152
Cdd:COG2730   41 NTVRLpvswerlqdpdnpYTLDEAyLERvDEVVDWAKARGLYVILDLHHAPGY-----QGWYDAATQERFIAFWRQLaER 115
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 927376739 153 FKNYPNLLGFFSGNEVIndaksaGVDPKYLRAVQRDIKQYI-ENNANRTI---PVGYSAADVLED 213
Cdd:COG2730  116 YKDYPNVLGFELLNEPH------GATWADWNALAQRAIDAIrATNPDRLIiveGNNWGGAHNLRA 174
 
Name Accession Description Interval E-value
Glyco_hydro_72 pfam03198
Glucanosyltransferase; This is a family of glycosylphosphatidylinositol-anchored beta(1-3) ...
17-344 1.32e-138

Glucanosyltransferase; This is a family of glycosylphosphatidylinositol-anchored beta(1-3)glucanosyltransferases. The active site residues in the Aspergillus fumigatus example Swiss:B0XT72 are the two glutamate residues at 160 and 261.


Pssm-ID: 397351 [Multi-domain]  Cd Length: 315  Bit Score: 401.75  E-value: 1.32e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927376739   17 TSAMIPIEIIGNRFIKPavdarDAGEVFFVTGVDYQPGGSSgyQDSNPTDVLSDAEACYRDAYVLQNLGskVNVIRVYTV 96
Cdd:pfam03198   6 FAATPPIEIKGNKFFDS-----KNGEQFYIKGVDYQPGGSS--ENSTLVDPLADADVCKRDIPYFKELG--INTIRVYAV 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927376739   97 NPELNHDECMSIFNSAGIYVMIDVNSPlsGESLDRYNPSQSYTYSYMERVFKMVDAFKNYPNLLGFFSGNEVINDAKSAG 176
Cdd:pfam03198  77 DPSLNHDECMKALSDAGIYVILDLNTP--KESINRADPAGSYNVDYLERYFAVIDAFKNYTNVLGFFAGNEVTNDASNTD 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927376739  177 vDPKYLRAVQRDIKQYIENNANRTIPVGYSAADVLEdgLREVTLEYMLCsidGDEDdlSKSDFFGINSYEWCsGVSDWAS 256
Cdd:pfam03198 155 -ASPYVKAAIRDMKQYISKHKYRTIPVGYSAADDAD--TRVQLADYFAC---GDDD--ERADFFGINMYEWC-GYSSFKT 225
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927376739  257 SGYGELNKTISNSTIPVFFSEYGCITKTPRTFDEVSEGVYGGLVNTLSGGLIYEYSTEANDYGLVEIASNGSVTIKKDYD 336
Cdd:pfam03198 226 SGYDDRTKEFENYSIPVFFSEYGCNKVTPRPFTEVSALYSSDMTSVFSGGLVYEYSEEANNYGLVSIDGDDVVTTLADFN 305

                  ....*...
gi 927376739  337 NLKSQLEN 344
Cdd:pfam03198 306 NLKSEYAK 313
BglC COG2730
Aryl-phospho-beta-D-glucosidase BglC, GH1 family [Carbohydrate transport and metabolism];
89-213 4.85e-04

Aryl-phospho-beta-D-glucosidase BglC, GH1 family [Carbohydrate transport and metabolism];


Pssm-ID: 442036 [Multi-domain]  Cd Length: 295  Bit Score: 41.95  E-value: 4.85e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927376739  89 NVIRV-------------YTVNPE-LNH-DECMSIFNSAGIYVMIDVNSPLSGesldrYNPSQSYTYSYMERVFKMV-DA 152
Cdd:COG2730   41 NTVRLpvswerlqdpdnpYTLDEAyLERvDEVVDWAKARGLYVILDLHHAPGY-----QGWYDAATQERFIAFWRQLaER 115
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 927376739 153 FKNYPNLLGFFSGNEVIndaksaGVDPKYLRAVQRDIKQYI-ENNANRTI---PVGYSAADVLED 213
Cdd:COG2730  116 YKDYPNVLGFELLNEPH------GATWADWNALAQRAIDAIrATNPDRLIiveGNNWGGAHNLRA 174
Cellulase pfam00150
Cellulase (glycosyl hydrolase family 5);
111-295 7.06e-03

Cellulase (glycosyl hydrolase family 5);


Pssm-ID: 395098 [Multi-domain]  Cd Length: 272  Bit Score: 38.51  E-value: 7.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927376739  111 SAGIYVMIDVNSPlsGESLDRYNPSQSYTYSYMERVFK-MVDAFKNYPNLlGFFSGNEViNDAKSAGVDPKYLRAVQRDI 189
Cdd:pfam00150  76 DNGMYVIIDWHHD--GGWPGDPNGNIDTAKAFFKKIWTqIATRYGNNPNV-IFELMNEP-HGNDQATWADDVKDYAQEAI 151
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927376739  190 KQYIENNANRTIPVG---YSAAdvledgLREVTLEYmlcsiDGDEDDL-------SKSDFFGINSYEWCSGVSDWAssgY 259
Cdd:pfam00150 152 DAIRAAGPNNLIIVGgnsWSQN------PDGAALND-----PNDDDNLiysvhfyAPSDFSGTWFDCEDPTNLAQR---L 217
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 927376739  260 GELNKTISNSTIPVFFSEYGCITKTPRTFDEVSEGV 295
Cdd:pfam00150 218 RAAANWALDNGIPVFIGEFGGGNADGPCRDEAEKWL 253
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH