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Conserved domains on  [gi|829978050|ref|XP_012606506|]
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microtubule-associated protein tau isoform X3 [Microcebus murinus]

Protein Classification

PHA03247 and Tubulin-binding domain-containing protein( domain architecture ID 10450448)

PHA03247 and Tubulin-binding domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 145-579 1.31e-12

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 72.28  E-value: 1.31e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  145 PGPHVQPQLGGEASGVSVPPVGETPREAPGPVTAR------PPQQ-RPLRPAPPaTGGPQQPPQGWAAEARAQATIVPPG 217
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRarrpdaPPQSaRPRAPVDD-RGDPRGPAPPSPLPPDTHAPDPPPP 2629

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  218 HPRTEPGSAEVVQESVLREPGRKTADTGTRGLSHQQVSTMPGAPPLPKGPreaTQQPSGTGPEDAEGSRRGSELPKhqla 297
Cdd:PHA03247 2630 SPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSP---PQRPRRRAARPTVGSLTSLADPP---- 2702

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  298 gdlrqegrlPKGPGGKERPWGEEEEDEDRDVDESSPQDSPPSQASPTPAGPPFQTASREAVGVPGFPVEGAIPlPADFLS 377
Cdd:PHA03247 2703 ---------PPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGP-PAPAPP 2772

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  378 KASADAPATEPGRPGAGPAAEEQDSAPEFTFHVEIKANVPKEQArSERDLERAVSPGEEPEAQDPSAGEDAKEAdlPEPS 457
Cdd:PHA03247 2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAA-ALPPAASPAGPLPPPTSAQPTAPPPPPGP--PPPS 2849

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  458 EKRPAAGLRGKPVSRVPQLKARMVSKGRDGTGNDDKKAKTSTPSSAKTLKTRPCLSPKRPTPGSSDPPT------QPCSP 531
Cdd:PHA03247 2850 LPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQpqpqppPPPQP 2929

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|..
gi 829978050  532 AVRPEPPSCPQHASSVTARTGGA----GAKETKLKGADGKTKIATPRGTAPP 579
Cdd:PHA03247 2930 QPPPPPPPRPQPPLAPTTDPAGAgepsGAVPQPWLGALVPGRVAVPRFRVPQ 2981
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 693-722 2.44e-11

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 58.58  E-value: 2.44e-11
                          10        20        30
                  ....*....|....*....|....*....|
gi 829978050  693 VQIVYKPVDLSKVTSKCGSLGNIHHKPGGG 722
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 724-754 1.50e-10

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 56.27  E-value: 1.50e-10
                          10        20        30
                  ....*....|....*....|....*....|.
gi 829978050  724 VEVKSEKLDFKdRVQSKIGSLDNITHVPGGG 754
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 670-691 8.31e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 48.56  E-value: 8.31e-08
                          10        20
                  ....*....|....*....|..
gi 829978050  670 DLKNVRSKIGSTENLKHQPGGG 691
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
PRK07764 super family cl35613
DNA polymerase III subunits gamma and tau; Validated
 48-236 2.01e-04

DNA polymerase III subunits gamma and tau; Validated


The actual alignment was detected with superfamily member PRK07764:

Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.98  E-value: 2.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  48 PQTPADDGSEEPGSETSDAKSTPTAEDVTAPLVGERAPGEQAAAQPRTEIPEGTTAEEAGIGD-TPNLEDQAAGHVTQEQ 126
Cdd:PRK07764 613 ARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGaAPAAPPPAPAPAAPAA 692

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 127 WRVAGQQREAPERPLVAEPGPHVQP----------QLGGEASGVSVPPVGETPREAPGPVTARPPQQRPLRPAPPATGGP 196
Cdd:PRK07764 693 PAGAAPAQPAPAPAATPPAGQADDPaaqppqaaqgASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAA 772

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 829978050 197 QQPPQGWAAEARAQATIVPPGHPRTePGSAEVVQESVLRE 236
Cdd:PRK07764 773 APPPSPPSEEEEMAEDDAPSMDDED-RRDAEEVAMELLEE 811
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 145-579 1.31e-12

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 72.28  E-value: 1.31e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  145 PGPHVQPQLGGEASGVSVPPVGETPREAPGPVTAR------PPQQ-RPLRPAPPaTGGPQQPPQGWAAEARAQATIVPPG 217
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRarrpdaPPQSaRPRAPVDD-RGDPRGPAPPSPLPPDTHAPDPPPP 2629

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  218 HPRTEPGSAEVVQESVLREPGRKTADTGTRGLSHQQVSTMPGAPPLPKGPreaTQQPSGTGPEDAEGSRRGSELPKhqla 297
Cdd:PHA03247 2630 SPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSP---PQRPRRRAARPTVGSLTSLADPP---- 2702

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  298 gdlrqegrlPKGPGGKERPWGEEEEDEDRDVDESSPQDSPPSQASPTPAGPPFQTASREAVGVPGFPVEGAIPlPADFLS 377
Cdd:PHA03247 2703 ---------PPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGP-PAPAPP 2772

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  378 KASADAPATEPGRPGAGPAAEEQDSAPEFTFHVEIKANVPKEQArSERDLERAVSPGEEPEAQDPSAGEDAKEAdlPEPS 457
Cdd:PHA03247 2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAA-ALPPAASPAGPLPPPTSAQPTAPPPPPGP--PPPS 2849

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  458 EKRPAAGLRGKPVSRVPQLKARMVSKGRDGTGNDDKKAKTSTPSSAKTLKTRPCLSPKRPTPGSSDPPT------QPCSP 531
Cdd:PHA03247 2850 LPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQpqpqppPPPQP 2929

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|..
gi 829978050  532 AVRPEPPSCPQHASSVTARTGGA----GAKETKLKGADGKTKIATPRGTAPP 579
Cdd:PHA03247 2930 QPPPPPPPRPQPPLAPTTDPAGAgepsGAVPQPWLGALVPGRVAVPRFRVPQ 2981
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 693-722 2.44e-11

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 58.58  E-value: 2.44e-11
                          10        20        30
                  ....*....|....*....|....*....|
gi 829978050  693 VQIVYKPVDLSKVTSKCGSLGNIHHKPGGG 722
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 724-754 1.50e-10

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 56.27  E-value: 1.50e-10
                          10        20        30
                  ....*....|....*....|....*....|.
gi 829978050  724 VEVKSEKLDFKdRVQSKIGSLDNITHVPGGG 754
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 670-691 8.31e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 48.56  E-value: 8.31e-08
                          10        20
                  ....*....|....*....|..
gi 829978050  670 DLKNVRSKIGSTENLKHQPGGG 691
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 48-236 2.01e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.98  E-value: 2.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  48 PQTPADDGSEEPGSETSDAKSTPTAEDVTAPLVGERAPGEQAAAQPRTEIPEGTTAEEAGIGD-TPNLEDQAAGHVTQEQ 126
Cdd:PRK07764 613 ARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGaAPAAPPPAPAPAAPAA 692

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 127 WRVAGQQREAPERPLVAEPGPHVQP----------QLGGEASGVSVPPVGETPREAPGPVTARPPQQRPLRPAPPATGGP 196
Cdd:PRK07764 693 PAGAAPAQPAPAPAATPPAGQADDPaaqppqaaqgASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAA 772

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 829978050 197 QQPPQGWAAEARAQATIVPPGHPRTePGSAEVVQESVLRE 236
Cdd:PRK07764 773 APPPSPPSEEEEMAEDDAPSMDDED-RRDAEEVAMELLEE 811
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 44-223 2.00e-03

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 41.95  E-value: 2.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050   44 KESSPQTPADDGSEEPGSETSDAKSTPTAEDVTAPLvgeRAPGEQAAAQPRTEIPEGTTAEEAGIGDTPnledQAAGHVT 123
Cdd:pfam09770 168 KKAAAPAPAPQPAAQPASLPAPSRKMMSLEEVEAAM---RAQAKKPAQQPAPAPAQPPAAPPAQQAQQQ----QQFPPQI 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  124 QEQWRVAGQQREAPERPLVAEPgPHV--QPQLGGEASGV-SVPPVGETPREAPGPVTARPPQ--QRPLRPAPPATGGPQQ 198
Cdd:pfam09770 241 QQQQQPQQQPQQPQQHPGQGHP-VTIlqRPQSPQPDPAQpSIQPQAQQFHQQPPPVPVQPTQilQNPNRLSAARVGYPQN 319

                         170       180
                  ....*....|....*....|....*
gi 829978050  199 PPQGWAAEARAQATIVPPGHPRTEP 223
Cdd:pfam09770 320 PQPGVQPAPAHQAHRQQGSFGRQAP 344
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 145-579 1.31e-12

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 72.28  E-value: 1.31e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  145 PGPHVQPQLGGEASGVSVPPVGETPREAPGPVTAR------PPQQ-RPLRPAPPaTGGPQQPPQGWAAEARAQATIVPPG 217
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRarrpdaPPQSaRPRAPVDD-RGDPRGPAPPSPLPPDTHAPDPPPP 2629

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  218 HPRTEPGSAEVVQESVLREPGRKTADTGTRGLSHQQVSTMPGAPPLPKGPreaTQQPSGTGPEDAEGSRRGSELPKhqla 297
Cdd:PHA03247 2630 SPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSP---PQRPRRRAARPTVGSLTSLADPP---- 2702

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  298 gdlrqegrlPKGPGGKERPWGEEEEDEDRDVDESSPQDSPPSQASPTPAGPPFQTASREAVGVPGFPVEGAIPlPADFLS 377
Cdd:PHA03247 2703 ---------PPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGP-PAPAPP 2772

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  378 KASADAPATEPGRPGAGPAAEEQDSAPEFTFHVEIKANVPKEQArSERDLERAVSPGEEPEAQDPSAGEDAKEAdlPEPS 457
Cdd:PHA03247 2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAA-ALPPAASPAGPLPPPTSAQPTAPPPPPGP--PPPS 2849

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  458 EKRPAAGLRGKPVSRVPQLKARMVSKGRDGTGNDDKKAKTSTPSSAKTLKTRPCLSPKRPTPGSSDPPT------QPCSP 531
Cdd:PHA03247 2850 LPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQpqpqppPPPQP 2929

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|..
gi 829978050  532 AVRPEPPSCPQHASSVTARTGGA----GAKETKLKGADGKTKIATPRGTAPP 579
Cdd:PHA03247 2930 QPPPPPPPRPQPPLAPTTDPAGAgepsGAVPQPWLGALVPGRVAVPRFRVPQ 2981
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 693-722 2.44e-11

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 58.58  E-value: 2.44e-11
                          10        20        30
                  ....*....|....*....|....*....|
gi 829978050  693 VQIVYKPVDLSKVTSKCGSLGNIHHKPGGG 722
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 77-458 9.71e-11

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 65.39  E-value: 9.71e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  77 APLVGERAPGEQAAAQPRTEIPEGTTAEEAGIGDTPNLEDQAAGHVTQEQWRVAGQQREAPERPLVAEPGPHVQ-PQLGG 155
Cdd:PRK07764 385 LGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPaAAPSA 464

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 156 EASGVSVPPVGETPREAPGPVTARPPQQRPLRPAPPATGGPQQPPQG------------------WAAEARAQATIVPP- 216
Cdd:PRK07764 465 QPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATlrerwpeilaavpkrsrkTWAILLPEATVLGVr 544

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 217 ------GHPR-------TEPGSAEVVQESVLREPG-----RKTADTGTRGLSHQQVSTMPGAPPLPKGPR-EATQQPSGT 277
Cdd:PRK07764 545 gdtlvlGFSTgglarrfASPGNAEVLVTALAEELGgdwqvEAVVGPAPGAAGGEGPPAPASSGPPEEAARpAAPAAPAAP 624

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 278 GPEDAEGSRRGSELPKHQLAGDLRQEGRLPKG---PGGKERPWGEEEEDEDRDVDESSPQDSPPSQASPTPAGPPfQTAS 354
Cdd:PRK07764 625 AAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHvavPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPA-QPAP 703

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 355 REAVGVPGFPVEGAIPLPADFLSKASADAPATEPGRPGAGPAAEEQDSAPeftfhveikanvPKEQARSERDLERAVSPG 434
Cdd:PRK07764 704 APAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAG------------APAQPPPPPAPAPAAAPA 771

                        410       420
                 ....*....|....*....|....
gi 829978050 435 EEPEAQDPSAGEDAKEADLPEPSE 458
Cdd:PRK07764 772 AAPPPSPPSEEEEMAEDDAPSMDD 795
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 724-754 1.50e-10

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 56.27  E-value: 1.50e-10
                          10        20        30
                  ....*....|....*....|....*....|.
gi 829978050  724 VEVKSEKLDFKdRVQSKIGSLDNITHVPGGG 754
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 137-525 7.23e-09

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 59.80  E-value: 7.23e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  137 PERPLVAEPGPHVQPQLGGEASGVSVPPVGETPREAPGPVTARPPQQRPLRPAPPAT---GGPQQPPQGWAAEARAQATI 213
Cdd:PHA03307   65 FEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPppaSPPPSPAPDLSEMLRPVGSP 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  214 VPPGHPRTEPGSAevvqesvlrEPGRKTADTGTRGLShqqvstmpgAPPLPKGPREATQQPSGTGPEDAEGSRRGSELPK 293
Cdd:PHA03307  145 GPPPAASPPAAGA---------SPAAVASDAASSRQA---------ALPLSSPEETARAPSSPPAEPPPSTPPAAASPRP 206

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  294 HQLAGDLRQEGRLPKGPGGKERPWGEEEEDEDRDVDESSPQDSPPSQASPTPAGPPFQTASREAVGVPGFPvEGAIPLPA 373
Cdd:PHA03307  207 PRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNG-PSSRPGPA 285

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  374 DFLSKASADAPATEPGRPGAGPAAEEQDSAPEFTFHVEikANVPKEQARSERDLERAVSPGEEPeAQDPSAGEDAKEADL 453
Cdd:PHA03307  286 SSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRE--SSSSSTSSSSESSRGAAVSPGPSP-SRSPSPSRPPPPADP 362

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  454 PEPSEKRPAAGLRGKPVSRVPQLKARMVSK-------GRDGTGNDDKKAKTSTPSSAKTLKTRPCLSPK------RPTPG 520
Cdd:PHA03307  363 SSPRKRPRPSRAPSSPAASAGRPTRRRARAavagrarRRDATGRFPAGRPRPSPLDAGAASGAFYARYPlltpsgEPWPG 442


                  ....*
gi 829978050  521 SSDPP 525
Cdd:PHA03307  443 SPPPP 447
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 670-691 8.31e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 48.56  E-value: 8.31e-08
                          10        20
                  ....*....|....*....|..
gi 829978050  670 DLKNVRSKIGSTENLKHQPGGG 691
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 48-445 1.17e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 55.71  E-value: 1.17e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050   48 PQTPADDGSEEPGSETsdAKSTPTAEDVTAPLVGERAPGEQAAAQPRTEIPEGTT------AEEAGIGDTPNLEDQAAGH 121
Cdd:PHA03247 2628 PPSPSPAANEPDPHPP--PTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrprrrAARPTVGSLTSLADPPPPP 2705

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  122 VTQEqwrvagqqrEAPERPLVAEPGPHVQPQLGGEASGVSVPPVGETPREAPG-PVTARPPQQRPLRPAPPATGGPQQPP 200
Cdd:PHA03247 2706 PTPE---------PAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAtPGGPARPARPPTTAGPPAPAPPAAPA 2776

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  201 QG--WAAEARAQATIVPPGHPRTEPGSAEVVQESVLREPGRKTADTGTRGLSHQQVSTMPGAPPLPKGPREATQQPSGTG 278
Cdd:PHA03247 2777 AGppRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSV 2856

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  279 PEDAEGSRRGSELPKhqlagdlrqegrlPKGPGGKERPWGEEEEDEDRDVDESS---PQDSPPSQASPTPAGPPFQTASR 355
Cdd:PHA03247 2857 APGGDVRRRPPSRSP-------------AAKPAAPARPPVRRLARPAVSRSTESfalPPDQPERPPQPQAPPPPQPQPQP 2923

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  356 EAVGVPGFPVEgaiplpadflSKASADAPATEPGRPGAGPAAEEQDSAPEFTFHVEIKANVPKEQARSERDLERAVSPGE 435
Cdd:PHA03247 2924 PPPPQPQPPPP----------PPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASST 2993

                         410
                  ....*....|
gi 829978050  436 EPEAQDPSAG 445
Cdd:PHA03247 2994 PPLTGHSLSR 3003
PHA03247 PHA03247
large tegument protein UL36; Provisional
 334-671 6.81e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.40  E-value: 6.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  334 QDSPPSQASPTPAGP------------PFQTASREAVGVPGFPVEGAIPLPADfLSKASADAPATEPGRPGAGPAAEEQD 401
Cdd:PHA03247 2566 RSVPPPRPAPRPSEPavtsrarrpdapPQSARPRAPVDDRGDPRGPAPPSPLP-PDTHAPDPPPPSPSPAANEPDPHPPP 2644

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  402 SAPEFTFHVEIKANVPKEQARSERDLERAVSPGEEPEAQDPSAGED--------AKEADLPEPSEKRPAAGLRGKPVSRV 473
Cdd:PHA03247 2645 TVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPtvgsltslADPPPPPPTPEPAPHALVSATPLPPG 2724

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  474 PQLKARMVSKGRDGTGNDDKKAKTSTPSSAKTLKTRPCLS-PKRPTPgSSDPPTQPCSPAVRPEPPSCPQHASSVTARTG 552
Cdd:PHA03247 2725 PAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAgPPAPAP-PAAPAAGPPRRLTRPAVASLSESRESLPSPWD 2803

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  553 GAGAKETKLKGADGKTKIATPRGTAPPGQKGANATRIPAKTPPAPKTPPGsGEPAKSGDRSGYSSPGSPgtpgsrsrtPS 632
Cdd:PHA03247 2804 PADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG-GSVAPGGDVRRRPPSRSP---------AA 2873

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 829978050  633 LPTPPTREP-KKVAVVRTPPKSPSSAKSRLQTAPVPMPDL 671
Cdd:PHA03247 2874 KPAAPARPPvRRLARPAVSRSTESFALPPDQPERPPQPQA 2913
PHA03247 PHA03247
large tegument protein UL36; Provisional
 303-669 1.74e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 52.25  E-value: 1.74e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  303 EGRLPKGPGGKERPWGEEEEDEDRDVDESSPQDSPPSQASPTPAGPP--------FQTASREAVGVPGFPVEGAIPLPAd 374
Cdd:PHA03247 2485 EARFPFAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPDEPVGEPVHPrmltwirgLEELASDDAGDPPPPLPPAAPPAA- 2563

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  375 flskASADAPATEPGRPGAGPAAEEQDSAPeftfhveikaNVPKEQARSERDLEravSPGEEPEAQDPSAGEDAKEADLP 454
Cdd:PHA03247 2564 ----PDRSVPPPRPAPRPSEPAVTSRARRP----------DAPPQSARPRAPVD---DRGDPRGPAPPSPLPPDTHAPDP 2626

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  455 EPSEKRPAAGLRGKPVSrvpqlkARMVSKGRDGTGNDDKKAKTSTPSSAKTLKTRPCLSPKRPTPGSSDPPTQPCSPAVR 534
Cdd:PHA03247 2627 PPPSPSPAANEPDPHPP------PTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLAD 2700

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  535 PEPP-----SCPQHASSVTARTGGAGAKetklkgadGKTKIATPRGTAPPGQKGANATRIPAKTPPAPKTPPGSGEPAKS 609
Cdd:PHA03247 2701 PPPPpptpePAPHALVSATPLPPGPAAA--------RQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPP 2772

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 829978050  610 GDRSGYSSPGSPGTPGSR--SRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 669
Cdd:PHA03247 2773 AAPAAGPPRRLTRPAVASlsESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSA 2834
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 201-579 2.29e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 51.71  E-value: 2.29e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  201 QGWAAEARAQATIVPPGHPRTEPGSAEVVQESVLREPGRKTAdtgtrGLSHQQVSTMPGAPPLPkgPREATQQPSGTGPE 280
Cdd:PHA03307   57 AGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPA-----SPAREGSPTPPGPSSPD--PPPPTPPPASPPPS 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  281 DAEGsrrgselpkhqLAGDLRQEGRLPKGPGGkERPWGEEEEDEDRDVDESSPQDSPPSQASPTPAGPPFQTASREAVGV 360
Cdd:PHA03307  130 PAPD-----------LSEMLRPVGSPGPPPAA-SPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPST 197

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  361 PGFPVEGAIPLPADFLSKASADAPATEPGRPGAGPAAEEQDSA----PEFTFHVEIKANVPKEQARSERDLERAVSPGEE 436
Cdd:PHA03307  198 PPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSssesSGCGWGPENECPLPRPAPITLPTRIWEASGWNG 277

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  437 PEAQDPSAGEDAKEADL-PEPSEKRPAAGLRGKPVSRVPqlkarmvSKGRDGTGNDDKKAKTSTPSSAktLKTRPCLSPK 515
Cdd:PHA03307  278 PSSRPGPASSSSSPRERsPSPSPSSPGSGPAPSSPRASS-------SSSSSRESSSSSTSSSSESSRG--AAVSPGPSPS 348

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 829978050  516 RPTPGSSDPPTQPCSPAVRPEPPSCPQHASSVTARTgGAGAKETKLKGADGKTKIATPRGTAPP 579
Cdd:PHA03307  349 RSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGR-PTRRRARAAVAGRARRRDATGRFPAGR 411
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
139-441 1.82e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 48.31  E-value: 1.82e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 139 RPLVAEPGPHvqpqlGGEASGVSVPPVGETPREAPGPVTARPPQQRPLRPAPPATGGPQQPPQGWAAEARAQATIVPPGH 218
Cdd:PRK07003 354 RMLAFEPAVT-----GGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPA 428

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 219 PRTEPGSAEVVQESVlrepgrkTADTGTRGLSHQQVSTMPGAPPLPKGPREATQQPSGTGPEDAEGSRRGSELPKHQLAG 298
Cdd:PRK07003 429 APAPPATADRGDDAA-------DGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSA 501

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 299 DLRQEGRLPKGPGGKERPwgeeeededrdvdesspqDSPPSQASPTP-AGPPFQTASREAVGVPGfpVEGAIPLPADFLS 377
Cdd:PRK07003 502 ATPAAVPDARAPAAASRE------------------DAPAAAAPPAPeARPPTPAAAAPAARAGG--AAAALDVLRNAGM 561

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 829978050 378 KASAD--APATEPGRPGAGPAAEEQDSAPeftfhvEIKANVPKEQARSERDLERAVSPGEEPEAQD 441
Cdd:PRK07003 562 RVSSDrgARAAAAAKPAAAPAAAPKPAAP------RVAVQVPTPRARAATGDAPPNGAARAEQAAE 621
PHA03247 PHA03247
large tegument protein UL36; Provisional
 152-680 2.50e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 2.50e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  152 QLGGEASGVSVPPVGETPReAPGPVTARPPQQRPLRPAPPATGGPQQPPQGWAAEARAQATIVPPGHPRTEPGSAEVVQE 231
Cdd:PHA03247 2542 ELASDDAGDPPPPLPPAAP-PAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPD 2620

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  232 SvlrepgrktadtgtrglshqqvstmPGAPPLPKGPREATQQPSGTGPEDAEGSRRGSELPKHQLAGDLRQEGRLPKGPG 311
Cdd:PHA03247 2621 T-------------------------HAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQ 2675

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  312 GKERPWGEEEEDEDRDVDESSPQDSPPSQASPTPAGPPFQTASREAVGVPGFPVEGAIPLPADFLSKASADAPATepgrp 391
Cdd:PHA03247 2676 ASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAT----- 2750

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  392 gagPAAEEQDSAPEFTfhveikanvpkeqARSERDLERAVSPGEEPEAQDPSAGEDAKEADLPEPSEKRPAaglrgkpvs 471
Cdd:PHA03247 2751 ---PGGPARPARPPTT-------------AGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPA--------- 2805

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  472 rvpqlkarmvskgrdgtgndDKKAKTSTPSSAKTLKTRPCLSPKRPTPGSSDPPTQPCSPAVRPEPPSCPQHASSVTART 551
Cdd:PHA03247 2806 --------------------DPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRR 2865

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  552 GGAGAKETKlkgADGKTKIATPRGTAPPGQKGANATRIPAKTPPAPKTPPGSGEPAKSGDRSGYSSPGSPGTPGSRSRTP 631
Cdd:PHA03247 2866 PPSRSPAAK---PAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPP 2942

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 829978050  632 SLPTPPTRE-----------------PKKVAVVRTppKSPSSAKSRLQTAPVPMPDLKNVRSKIGS 680
Cdd:PHA03247 2943 LAPTTDPAGagepsgavpqpwlgalvPGRVAVPRF--RVPQPAPSREAPASSTPPLTGHSLSRVSS 3006
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
81-283 5.94e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 46.79  E-value: 5.94e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  81 GERAPGeQAAAQPRTEIPEGTTAEEAGigDTPNLEDQAAGHVTQEQWRVAGQQREAPERPLVAEPGPHVQPQLGGEASGV 160
Cdd:PRK12323 370 GGAGPA-TAAAAPVAQPAPAAAAPAAA--APAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGG 446

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 161 SVPPvgeTPREAPGPVTARPPQQRPLRPaPPATGGPQQPPQGWAAEARAQATIVPP-----------GHPRTEPGSAEVV 229
Cdd:PRK12323 447 APAP---APAPAAAPAAAARPAAAGPRP-VAAAAAAAPARAAPAAAPAPADDDPPPweelppefaspAPAQPDAAPAGWV 522

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 829978050 230 QESVLREPGRKTADTGtrglshQQVSTMPGAPPLPKGPREATQQPSGTGPEDAE 283
Cdd:PRK12323 523 AESIPDPATADPDDAF------ETLAPAPAAAPAPRAAAATEPVVAPRPPRASA 570
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 128-471 7.06e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 46.52  E-value: 7.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 128 RVAGQQREAPERPLVAEPGPHVQPQLGGEASGVSVPPVGETPREAPGPVTARPPQQRPLRPAPPATGGPQQPPQGWAAEA 207
Cdd:PRK07764 377 RLERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSP 456

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 208 RAQATIVPPGHPRTEPGSAEVVQESVLREPGRKTADTgtrglshQQVSTMPGAPPLP---KGPREA-------------- 270
Cdd:PRK07764 457 PPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAA-------PAAPAAPAAPAGAddaATLRERwpeilaavpkrsrk 529

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 271 -----TQQPSGTGPED--------AEGSRRGSELPKH----------QLAGDLRQEGRLPKGPGGKERPWGEEEEDEDRD 327
Cdd:PRK07764 530 twailLPEATVLGVRGdtlvlgfsTGGLARRFASPGNaevlvtalaeELGGDWQVEAVVGPAPGAAGGEGPPAPASSGPP 609

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 328 VDESSPQDSPPSQASPTPAGPPFQTASREAVGVPGFPVEGAIPLPADFLSKASADAPATEPGRPG-AGPAAEEQDSAPEf 406
Cdd:PRK07764 610 EEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGgAAPAAPPPAPAPA- 688

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 829978050 407 tfHVEIKANVPKEQARSERDLERAVSPGEEPEAQDPSAGEDAKEA------DLPEPSEKRPAAGLRGKPVS 471
Cdd:PRK07764 689 --APAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPspaaddPVPLPPEPDDPPDPAGAPAQ 757
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 50-283 8.23e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 46.13  E-value: 8.23e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  50 TPADDGSEEPGSETSDAKSTPTAEDVTAPlvgerAPGEQAAAQPRTEiPEGTTAEEAGIGDTPNLEDQAAGHVTQEQWRV 129
Cdd:PRK07764 587 VVGPAPGAAGGEGPPAPASSGPPEEAARP-----AAPAAPAAPAAPA-PAGAAAAPAEASAAPAPGVAAPEHHPKHVAVP 660

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 130 AGQQREAPERPLVAEPGPhvqpqLGGEASGVSVPPVGETPREAPGPVTARPPQQRPLRPAPPATGGPQQPPQGWAAEARA 209
Cdd:PRK07764 661 DASDGGDGWPAKAGGAAP-----AAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAA 735

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 829978050 210 QATIVPPGHPRTEPGSAEVVQESvlrePGRKTADTGTRGLSHQQVSTMPGAPPLpkgPREATQQPSGTGPEDAE 283
Cdd:PRK07764 736 DDPVPLPPEPDDPPDPAGAPAQP----PPPPAPAPAAAPAAAPPPSPPSEEEEM---AEDDAPSMDDEDRRDAE 802
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 308-660 1.37e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.55  E-value: 1.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  308 KGPGGKERPWGEEEEDEDRDVDESSPQDSPPSQASPTPAGPPFQTASREAVGVPGFPVEGAIPLPADFLSKASADAPATE 387
Cdd:PHA03307   59 AAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEML 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  388 PGRPGAGPAAEEQDSAPEftfhveIKANVPKEQARSERDLERAVSPGEEPEAQDPSAGedakeadlPEPSEKRPAAGLRG 467
Cdd:PHA03307  139 RPVGSPGPPPAASPPAAG------ASPAAVASDAASSRQAALPLSSPEETARAPSSPP--------AEPPPSTPPAAASP 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  468 KPVSRVPQLKARMVSKGRDGTGNDDKKAKTSTPSSAKTLKTRPCLSPK----RPTPGSSDPPTQPCSPAVRPEPPSCPQH 543
Cdd:PHA03307  205 RPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPEnecpLPRPAPITLPTRIWEASGWNGPSSRPGP 284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  544 ASSVTARTGGAGAketklkgadgktkiatPRGTAPPGQKGANATRIPAKTPPAPKTPPGSGEPAKSGDRSGYSSPGSPGT 623
Cdd:PHA03307  285 ASSSSSPRERSPS----------------PSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPS 348

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 829978050  624 PG---SRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSR 660
Cdd:PHA03307  349 RSpspSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRR 388
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 48-236 2.01e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.98  E-value: 2.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  48 PQTPADDGSEEPGSETSDAKSTPTAEDVTAPLVGERAPGEQAAAQPRTEIPEGTTAEEAGIGD-TPNLEDQAAGHVTQEQ 126
Cdd:PRK07764 613 ARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGaAPAAPPPAPAPAAPAA 692

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 127 WRVAGQQREAPERPLVAEPGPHVQP----------QLGGEASGVSVPPVGETPREAPGPVTARPPQQRPLRPAPPATGGP 196
Cdd:PRK07764 693 PAGAAPAQPAPAPAATPPAGQADDPaaqppqaaqgASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAA 772

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 829978050 197 QQPPQGWAAEARAQATIVPPGHPRTePGSAEVVQESVLRE 236
Cdd:PRK07764 773 APPPSPPSEEEEMAEDDAPSMDDED-RRDAEEVAMELLEE 811
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
152-407 5.72e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 43.33  E-value: 5.72e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 152 QLGGEASGVSVPPVGETPREAPGPVTARPPQQRPLRPAPPATggpqqPPQGWAAEARAQATIVPPGHPRTEPGSAEVVQE 231
Cdd:PRK12323 364 RPGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAA-----PAAAPAAAAAARAVAAAPARRSPAPEALAAARQ 438

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 232 SVLREPGRKTADTGTrglshqqvstmPGAPPLPkGPREATQQPSGTGPEDAEGSRRgselpkhqlagdlRQEGRLPKGPG 311
Cdd:PRK12323 439 ASARGPGGAPAPAPA-----------PAAAPAA-AARPAAAGPRPVAAAAAAAPAR-------------AAPAAAPAPAD 493

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 312 GKERPWGEEEEDEDRDvdesspqdsPPSQASPTPAGPPFQTASREAVGVPGFPVEGAIPLPADflSKASADAPATEPGRP 391
Cdd:PRK12323 494 DDPPPWEELPPEFASP---------APAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAA--APAPRAAAATEPVVA 562

                        250
                 ....*....|....*.
gi 829978050 392 GAGPAAEEQDSAPEFT 407
Cdd:PRK12323 563 PRPPRASASGLPDMFD 578
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 27-395 6.68e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.62  E-value: 6.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050   27 GDYTLLQDQEGDTDHGLKESSPQTPADDGSEEPGSETSDAKSTPTAEDVtaPLVGERAPGEQAAAQPRTEIPEGTTAEEA 106
Cdd:PHA03307   74 GPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPP--PASPPPSPAPDLSEMLRPVGSPGPPPAAS 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  107 GIGDTPNLEDQAAGHVTQEQWRVAGQQREAPERPLV--AEPGPHVQPQLGGEASGVSVPPVGETPREAPGPVTARpPQQR 184
Cdd:PHA03307  152 PPAAGASPAAVASDAASSRQAALPLSSPEETARAPSspPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGR-SAAD 230

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  185 PLRPAPPATGGPQQPPQGWAAEARAQATIVPPGHPRTEPGSAeVVQESVLREPGRKTADTGTRGLSHQQVSTMPGAPPLP 264
Cdd:PHA03307  231 DAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEA-SGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAP 309

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  265 KGPREATQQpSGTGPEDAEGSRRGSELPKHQLAGDLRQEGRLPKGPggkeRPWGEEEEDEDRDVDESSPQDSPPSQASPT 344
Cdd:PHA03307  310 SSPRASSSS-SSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPS----RPPPPADPSSPRKRPRPSRAPSSPAASAGR 384

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|.
gi 829978050  345 PAGPpfqtASREAVGVPGFPVEGAIPLPADFLSKASADAPATEPGRPGAGP 395
Cdd:PHA03307  385 PTRR----RARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYARYP 431
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
143-398 1.43e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.17  E-value: 1.43e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 143 AEPGPHVQPQLGGEASGVSVPPVGETPREAPGPVTARPPQQRPLRPAPPATGGPQQPPQGWAAEARAQATIVPPGHPRTE 222
Cdd:PRK12323 372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPA 451

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 223 PGSAEVvqesvlrePGRKTAdtgtrglshqqvstmPGAPPLPKGPREATQQPSGTGPEDAEGSRRGSELPKHQLAGDLRQ 302
Cdd:PRK12323 452 PAPAAA--------PAAAAR---------------PAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFAS 508

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 303 EGRLPKGPGgkerPWGEEEEDEDRDVDESSPQDSPPSQASPTPAGPPFQTASREAVGVPGFPVEGAIPLPADFlskaSAD 382
Cdd:PRK12323 509 PAPAQPDAA----PAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMF----DGD 580

                        250
                 ....*....|....*.
gi 829978050 383 APATEPGRPGAGPAAE 398
Cdd:PRK12323 581 WPALAARLPVRGLAQQ 596
PHA03247 PHA03247
large tegument protein UL36; Provisional
 46-293 1.55e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 1.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050   46 SSPQTPADDGSEEPGSETSDAKSTPTAEDVTAPLVGERAPGEQAAAQPRTEIPEGTTAEEAGIGDTPnleDQAAGHVTQE 125
Cdd:PHA03247 2777 AGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPP---GPPPPSLPLG 2853

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  126 QWRVAGQ--QREAPERPLVAEPgphvqpqlggeaSGVSVPPVGETPREAPGPVTARPPQQRPLRPAPPATGGPQQPPQGW 203
Cdd:PHA03247 2854 GSVAPGGdvRRRPPSRSPAAKP------------AAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQP 2921

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  204 AAEARAQATIVPPGHPRTEPGSAEVVQESVLREPGRKTADTgtrglshQQVSTMPGAPPLPKgPREATQQPSGTGPEDAE 283
Cdd:PHA03247 2922 QPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQP-------WLGALVPGRVAVPR-FRVPQPAPSREAPASST 2993

                         250
                  ....*....|
gi 829978050  284 GSRRGSELPK 293
Cdd:PHA03247 2994 PPLTGHSLSR 3003
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
309-545 1.89e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 41.76  E-value: 1.89e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 309 GPGGKERPWGEEEEDEDRDVDESSPQDSPPSQASPTPAGP-----------PFQT---ASREAVGVPGFPVEGAIPLPAD 374
Cdd:PRK07003 381 PAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAAtraeappaapaPPATadrGDDAADGDAPVPAKANARASAD 460

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 375 FLSKASADAPATEPgRPGAGPAaeeQDSAPEFTFHVEIKANVPKEQARSERDLERAVSPGEEPEAQDPSAgEDAKEADLP 454
Cdd:PRK07003 461 SRCDERDAQPPADS-GSASAPA---SDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAA-PPAPEARPP 535

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 455 EPSEKRPAAGLRGKPVSRVPQLKARM-VSKGRDGTGNDDKKAKTSTPSSAKTLKTRPCLSPkrPTPGS-SDPPTQPCSPA 532
Cdd:PRK07003 536 TPAAAAPAARAGGAAAALDVLRNAGMrVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQV--PTPRArAATGDAPPNGA 613

                        250
                 ....*....|...
gi 829978050 533 VRPEPPSCPQHAS 545
Cdd:PRK07003 614 ARAEQAAESRGAP 626
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 44-223 2.00e-03

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 41.95  E-value: 2.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050   44 KESSPQTPADDGSEEPGSETSDAKSTPTAEDVTAPLvgeRAPGEQAAAQPRTEIPEGTTAEEAGIGDTPnledQAAGHVT 123
Cdd:pfam09770 168 KKAAAPAPAPQPAAQPASLPAPSRKMMSLEEVEAAM---RAQAKKPAQQPAPAPAQPPAAPPAQQAQQQ----QQFPPQI 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  124 QEQWRVAGQQREAPERPLVAEPgPHV--QPQLGGEASGV-SVPPVGETPREAPGPVTARPPQ--QRPLRPAPPATGGPQQ 198
Cdd:pfam09770 241 QQQQQPQQQPQQPQQHPGQGHP-VTIlqRPQSPQPDPAQpSIQPQAQQFHQQPPPVPVQPTQilQNPNRLSAARVGYPQN 319

                         170       180
                  ....*....|....*....|....*
gi 829978050  199 PPQGWAAEARAQATIVPPGHPRTEP 223
Cdd:pfam09770 320 PQPGVQPAPAHQAHRQQGSFGRQAP 344
dnaA PRK14086
chromosomal replication initiator protein DnaA;
78-271 2.08e-03

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 41.73  E-value: 2.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  78 PLVGERAPGEQAaaQPRTEIPEGTTAEEAGIGDTPNLEDQAAGHVTQEQWRVAGQQREAPERPLVAEPGPHVQPQlggEA 157
Cdd:PRK14086  90 PSAGEPAPPPPH--ARRTSEPELPRPGRRPYEGYGGPRADDRPPGLPRQDQLPTARPAYPAYQQRPEPGAWPRAA---DD 164

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 158 SGVSVPPVGETPREAPGPVTARPPQQRPLRPaPPATGGPQQpPQGWAAEARAQATIVPPGH-----PRTEPGSAEVVQES 232
Cdd:PRK14086 165 YGWQQQRLGFPPRAPYASPASYAPEQERDRE-PYDAGRPEY-DQRRRDYDHPRPDWDRPRRdrtdrPEPPPGAGHVHRGG 242

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 829978050 233 vlrepgrktaDTGTRGLSHQQVSTMPGAP-PLPKGPREAT 271
Cdd:PRK14086 243 ----------PGPPERDDAPVVPIRPSAPgPLAAQPAPAP 272
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 45-271 2.59e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 41.61  E-value: 2.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050   45 ESSPQTPADDGSEEPGSETSDAKSTPTAEDVT------APLVGERAPGEQAA--AQPRTEIPEGTTAEEAGIGDTPNLED 116
Cdd:PRK10263  350 DVPPAQPTVAWQPVPGPQTGEPVIAPAPEGYPqqsqyaQPAVQYNEPLQQPVqpQQPYYAPAAEQPAQQPYYAPAPEQPA 429

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  117 QAAGHVTQEQWRVAGQQREAPERPLVAEPGPHVQPQlggeaSGVSVPPVGETPREAPGPVtarpPQQRPLRPAPPATG-G 195
Cdd:PRK10263  430 QQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTE-----QTYQQPAAQEPLYQQPQPV----EQQPVVEPEPVVEEtK 500

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  196 PQQPPQGWAAE-----ARAQATIVPPGHPRTEPgsaevVQESVLREPGRKTADTGtrglSHQQVSTMPGAPPLPKGPREA 270
Cdd:PRK10263  501 PARPPLYYFEEveekrAREREQLAAWYQPIPEP-----VKEPEPIKSSLKAPSVA----AVPPVEAAAAVSPLASGVKKA 571


                  .
gi 829978050  271 T 271
Cdd:PRK10263  572 T 572
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 335-670 2.75e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 41.31  E-value: 2.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  335 DSPPSQASPTPAGPPFQTASREAVGVpgFPVEGAIPLPADFLSKASADAPATEPGRPGAGPAAEEQDSAPEFTFHVEIKA 414
Cdd:PHA03307   17 GGEFFPRPPATPGDAADDLLSGSQGQ--LVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLST 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  415 NVPKEQARSERDLERAVSPGEEPEAQDPSAGedakeaDLPEPSEKRPAAGLRGKPVSRVPQLKARMVSKGRDGTGNDDKK 494
Cdd:PHA03307   95 LAPASPAREGSPTPPGPSSPDPPPPTPPPAS------PPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAAS 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  495 AKTSTPSSAKTLKTRPCLSPKRPTPGSSDPPTQPCSPAVRPEPPSCPQHASSVTART----GGAGAKETKLKGADGKTKI 570
Cdd:PHA03307  169 SRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGrsaaDDAGASSSDSSSSESSGCG 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  571 ATPRGTAP---PGQKGANATRIPAKTPPAPKTPPGSGEPAKS-GDRSGYSSPGSPGTPG-----------SRSRTPSLPT 635
Cdd:PHA03307  249 WGPENECPlprPAPITLPTRIWEASGWNGPSSRPGPASSSSSpRERSPSPSPSSPGSGPapssprassssSSSRESSSSS 328

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 829978050  636 PPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPD 670
Cdd:PHA03307  329 TSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPS 363
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
300-539 4.79e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 40.63  E-value: 4.79e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 300 LRQEGRLPKGPGGKERPwgeeEEDEDRDVDESSPQDSPPSQASPTPAGPPFQTASREAVGVPGFPVEGAiPLPADFLSKA 379
Cdd:PRK12323 358 LRMLAFRPGQSGGGAGP----ATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAA-PARRSPAPEA 432

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 380 SADAPATEPGRPGAGPAAEeqdSAPeftfhveikANVPKEQARserdleRAVSPGEEPEAQDPSAGEDAKEADLPEPSEK 459
Cdd:PRK12323 433 LAAARQASARGPGGAPAPA---PAP---------AAAPAAAAR------PAAAGPRPVAAAAAAAPARAAPAAAPAPADD 494

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 460 RPAaglrgkPVSRVPQLKARMVSKGRDGTGNDDKKAKTSTPSSAKTLKTRPCLSPKrPTPGSSDPPTQPCSPAVRPEPPS 539
Cdd:PRK12323 495 DPP------PWEELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPA-PAAAPAPRAAAATEPVVAPRPPR 567
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 42-227 6.03e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 6.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  42 GLKESSPQTPADDGSEEPGSETSDAKSTPTAEDV-TAPLVGERAPGEQAAAQPRTEIPEGTTAEEAGIGDTPNLEDQAAG 120
Cdd:PRK07764 599 GPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAaAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAP 678

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 121 HVTQEQWRVAGQQREAPERPLVAEPGPHVQPQLGGEASGVSVPPVGETPREAPGPVTAR---PPQQRPLRPAPPATGGPQ 197
Cdd:PRK07764 679 AAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDpvpLPPEPDDPPDPAGAPAQP 758

                        170       180       190
                 ....*....|....*....|....*....|
gi 829978050 198 QPPQgWAAEARAQATIVPPGHPRTEPGSAE 227
Cdd:PRK07764 759 PPPP-APAPAAAPAAAPPPSPPSEEEEMAE 787
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 314-654 7.27e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.97  E-value: 7.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 314 ERPWGEEEEDEDRDVDESSPQDSPPSQASPTPAGPPFQTASREAVGVPGFPVEGAIPLPADFLSKASADAPATEPGRPGA 393
Cdd:PRK07764 379 ERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPP 458

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 394 GPAAEEQDSAPEftfhveiKANVPKEQARSERDLERAVSPGEEPEAQDPSAGEDAKEAD------------LPEPSEKRP 461
Cdd:PRK07764 459 AAAPSAQPAPAP-------AAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAAtlrerwpeilaaVPKRSRKTW 531

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 462 A--------AGLRGKPVS---RVPQLKARMVSKG---------RDGTGND---------DKKAKTSTPSSAKTLKTRPcl 512
Cdd:PRK07764 532 AillpeatvLGVRGDTLVlgfSTGGLARRFASPGnaevlvtalAEELGGDwqveavvgpAPGAAGGEGPPAPASSGPP-- 609

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050 513 sPKRPTPGSSDPPTQPcSPAVRPEPPSCPQHASSVTARTGGAGAKETK--------LKGADGKTKIATPRGTAPPGQKGA 584
Cdd:PRK07764 610 -EEAARPAAPAAPAAP-AAPAPAGAAAAPAEASAAPAPGVAAPEHHPKhvavpdasDGGDGWPAKAGGAAPAAPPPAPAP 687

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 829978050 585 NATRIPAKTPPAPKTPPGSGEPAKSGDRSGYSSPGSPGTPGSR-SRTPSLPTPPTREPKKVAVVRTPPKSP 654
Cdd:PRK07764 688 AAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASApSPAADDPVPLPPEPDDPPDPAGAPAQP 758
PHA03247 PHA03247
large tegument protein UL36; Provisional
 157-399 8.18e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.92  E-value: 8.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  157 ASGVSVPPVGETPREAPGPVTARPPQQRPLRPAPPAtggpQQPPQGWAAEARAQATIVPPGHPRTEPGSAEVVQEsvlrE 236
Cdd:PHA03247  256 APPPVVGEGADRAPETARGATGPPPPPEAAAPNGAA----APPDGVWGAALAGAPLALPAPPDPPPPAPAGDAEE----E 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  237 PGRKTADTGTRGLSHQQVSTMPGappLPKGPReatqqPSGTGPEDAEGSRRGSELPKH-QLAGDLRQEGRLPKGPGGKEr 315
Cdd:PHA03247  328 DDEDGAMEVVSPLPRPRQHYPLG---FPKRRR-----PTWTPPSSLEDLSAGRHHPKRaSLPTRKRRSARHAATPFARG- 398

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829978050  316 PWGEEEEDEDRDVDESSPQDSPPsqasPTPAGPPFQTASREAVGVPGfpvEGAIPLPADFLSKASADAPATEPGRPGAGP 395
Cdd:PHA03247  399 PGGDDQTRPAAPVPASVPTPAPT----PVPASAPPPPATPLPSAEPG---SDDGPAPPPERQPPAPATEPAPDDPDDATR 471


                  ....
gi 829978050  396 AAEE 399
Cdd:PHA03247  472 KALD 475
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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