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Conserved domains on  [gi|829904633|ref|XP_012591532|]
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uromodulin isoform X1 [Microcebus murinus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ZP smart00241
Zona pellucida (ZP) domain; ZP proteins are responsible for sperm-adhesion fo the zona ...
 372-621 6.28e-62

Zona pellucida (ZP) domain; ZP proteins are responsible for sperm-adhesion fo the zona pellucida. ZP domains are also present in multidomain transmembrane proteins such as glycoprotein GP2, uromodulin and TGF-beta receptor type III (betaglycan).


:

Pssm-ID: 214579  Cd Length: 252  Bit Score: 206.85  E-value: 6.28e-62
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829904633   372 ECGTADIKVSLSKCQLKSLGFEKVFMYLRDSRCSGFNERGNRDWVSVVTPAQAgpCGTVMTKNETHATYSNTLYLA---D 448
Cdd:smart00241   1 QCGEDQMVVSVSTDLLFPGGINVKGLTLGDPSCRPQFTDATSAFVSFEVPLNG--CGTRRQVNPDGIVYSNTLVVSpfhP 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829904633   449 EIIIRDRNIKINFACSYPLDMKVSLMTSLQPVVSVLNISVGgTGMFTVRMALFQSPAYTQPYQGSSVTmtTDAFLYVGII 528
Cdd:smart00241  79 GFITRDDRAAYHFQCFYPENEKVSLNLDVSTIPPTELSSVS-EGPLTCSYRLYKDDSFGSPYQSADYV--LGDPVYHEWE 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829904633   529 LDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCP--RLEDSTVQVVENGESpQSRFSVQMFRFTgNYDLVYLHCEV 606
Cdd:smart00241 156 CDGADDPPLGLLVDNCYATPGPDPSSGPKYFIIDNGCPvdGYLDSTIPYNSNPLH-RARFSVKVFKFA-DRSLVYFHCQI 233

                          250
                   ....*....|....*..
gi 829904633   607 YLCD--SVIENCKPTCS 621
Cdd:smart00241 234 RLCDkdDGSSCDGPACS 250
EGF_3 pfam12947
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ...
 150-186 1.38e-07

EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.


:

Pssm-ID: 463759 [Multi-domain]  Cd Length: 36  Bit Score: 47.98  E-value: 1.38e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 829904633  150 CSEsGLSHCHALATCVNEEGSYSCVCPAGYLGDGWHC 186
Cdd:pfam12947   1 CSD-NNGGCHPNATCTNTGGSFTCTCNDGYTGDGVTC 36
EGF_CA pfam07645
Calcium-binding EGF domain;
103-135 2.33e-06

Calcium-binding EGF domain;


:

Pssm-ID: 429571  Cd Length: 32  Bit Score: 44.54  E-value: 2.33e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 829904633  103 DLDECAIPEvHNCSANENCVNTPGFYECVCLEG 135
Cdd:pfam07645   1 DVDECATGT-HNCPANTVCVNTIGSFECRCPDG 32
EGF_3 super family cl48154
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ...
 72-101 6.43e-04

EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.


The actual alignment was detected with superfamily member pfam12947:

Pssm-ID: 463759 [Multi-domain]  Cd Length: 36  Bit Score: 37.58  E-value: 6.43e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 829904633   72 DCHSNATCMEDGVVTTCFCQEGFTGDGLTC 101
Cdd:pfam12947   7 GCHPNATCTNTGGSFTCTCNDGYTGDGVTC 36
 
Name Accession Description Interval E-value
ZP smart00241
Zona pellucida (ZP) domain; ZP proteins are responsible for sperm-adhesion fo the zona ...
 372-621 6.28e-62

Zona pellucida (ZP) domain; ZP proteins are responsible for sperm-adhesion fo the zona pellucida. ZP domains are also present in multidomain transmembrane proteins such as glycoprotein GP2, uromodulin and TGF-beta receptor type III (betaglycan).


Pssm-ID: 214579  Cd Length: 252  Bit Score: 206.85  E-value: 6.28e-62
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829904633   372 ECGTADIKVSLSKCQLKSLGFEKVFMYLRDSRCSGFNERGNRDWVSVVTPAQAgpCGTVMTKNETHATYSNTLYLA---D 448
Cdd:smart00241   1 QCGEDQMVVSVSTDLLFPGGINVKGLTLGDPSCRPQFTDATSAFVSFEVPLNG--CGTRRQVNPDGIVYSNTLVVSpfhP 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829904633   449 EIIIRDRNIKINFACSYPLDMKVSLMTSLQPVVSVLNISVGgTGMFTVRMALFQSPAYTQPYQGSSVTmtTDAFLYVGII 528
Cdd:smart00241  79 GFITRDDRAAYHFQCFYPENEKVSLNLDVSTIPPTELSSVS-EGPLTCSYRLYKDDSFGSPYQSADYV--LGDPVYHEWE 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829904633   529 LDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCP--RLEDSTVQVVENGESpQSRFSVQMFRFTgNYDLVYLHCEV 606
Cdd:smart00241 156 CDGADDPPLGLLVDNCYATPGPDPSSGPKYFIIDNGCPvdGYLDSTIPYNSNPLH-RARFSVKVFKFA-DRSLVYFHCQI 233

                          250
                   ....*....|....*..
gi 829904633   607 YLCD--SVIENCKPTCS 621
Cdd:smart00241 234 RLCDkdDGSSCDGPACS 250
Zona_pellucida pfam00100
Zona pellucida-like domain;
373-621 2.67e-61

Zona pellucida-like domain;


Pssm-ID: 459673 [Multi-domain]  Cd Length: 254  Bit Score: 205.53  E-value: 2.67e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829904633  373 CGTADIKVSLSKCQLKSLGF--EKVFMYLRDSRCSGFNERGNRDWVSVVTPAQAgpCGTVMTKNETHATYSNTLYLADE- 449
Cdd:pfam00100   1 CTPDTMTVSISKCLLVPSGLlsSLSLLGGLDPSCKPVSNTNGSPAVLFEFPLTG--CGTTVQVNGTHIIYSNTLYSSTDl 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829904633  450 ---IIIRDRNIKINFACSYPLDMKVSLMTSLQPvvSVLNISVGGTGMFTVRMALFQSPAYTQPYQGSSVTMTTDAFLYVG 526
Cdd:pfam00100  79 rsgIIRRTITRRLPFSCSYPRSSLVSLLVVAPP--SPVPITVSGSGVFLVSMDLYYDSSYTSPYSPYPVTVLLGDPLYVE 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829904633  527 IILDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCPRLEDST--VQVVENGESPQSRFSVQMFRFTGNY-DLVYLH 603
Cdd:pfam00100 157 VSLLSRTDPNLVLVLDNCWATPSPNPTSSPQYQLIVNGCPNDGDSTypVSSLSNGPSHYVRFSFKAFRFVGSSiSQVYLH 236

                         250
                  ....*....|....*...
gi 829904633  604 CEVYLCDSVIENCKPTCS 621
Cdd:pfam00100 237 CSVSVCSSDSNSCGKSCS 254
EGF_3 pfam12947
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ...
 150-186 1.38e-07

EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.


Pssm-ID: 463759 [Multi-domain]  Cd Length: 36  Bit Score: 47.98  E-value: 1.38e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 829904633  150 CSEsGLSHCHALATCVNEEGSYSCVCPAGYLGDGWHC 186
Cdd:pfam12947   1 CSD-NNGGCHPNATCTNTGGSFTCTCNDGYTGDGVTC 36
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 146-187 3.54e-07

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 46.86  E-value: 3.54e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 829904633 146 DVDECSESGLshCHALATCVNEEGSYSCVCPAGYLGDgwHCE 187
Cdd:cd00054    1 DIDECASGNP--CQNGGTCVNTVGSYRCSCPPGYTGR--NCE 38
EGF_CA smart00179
Calcium-binding EGF-like domain;
146-187 4.37e-07

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.47  E-value: 4.37e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 829904633   146 DVDECSESGLshCHALATCVNEEGSYSCVCPAGYLgDGWHCE 187
Cdd:smart00179   1 DIDECASGNP--CQNGGTCVNTVGSYRCECPPGYT-DGRNCE 39
EGF_CA pfam07645
Calcium-binding EGF domain;
103-135 2.33e-06

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 44.54  E-value: 2.33e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 829904633  103 DLDECAIPEvHNCSANENCVNTPGFYECVCLEG 135
Cdd:pfam07645   1 DVDECATGT-HNCPANTVCVNTIGSFECRCPDG 32
EGF_CA smart00179
Calcium-binding EGF-like domain;
103-145 2.83e-05

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 41.46  E-value: 2.83e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 829904633   103 DLDECAipEVHNCSANENCVNTPGFYECVCLEGFreTPGLGCT 145
Cdd:smart00179   1 DIDECA--SGNPCQNGGTCVNTVGSYRCECPPGY--TDGRNCE 39
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 103-137 1.84e-04

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 39.16  E-value: 1.84e-04
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 829904633 103 DLDECAIPevHNCSANENCVNTPGFYECVCLEGFR 137
Cdd:cd00054    1 DIDECASG--NPCQNGGTCVNTVGSYRCSCPPGYT 33
EGF_3 pfam12947
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ...
 72-101 6.43e-04

EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.


Pssm-ID: 463759 [Multi-domain]  Cd Length: 36  Bit Score: 37.58  E-value: 6.43e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 829904633   72 DCHSNATCMEDGVVTTCFCQEGFTGDGLTC 101
Cdd:pfam12947   7 GCHPNATCTNTGGSFTCTCNDGYTGDGVTC 36
 
Name Accession Description Interval E-value
ZP smart00241
Zona pellucida (ZP) domain; ZP proteins are responsible for sperm-adhesion fo the zona ...
 372-621 6.28e-62

Zona pellucida (ZP) domain; ZP proteins are responsible for sperm-adhesion fo the zona pellucida. ZP domains are also present in multidomain transmembrane proteins such as glycoprotein GP2, uromodulin and TGF-beta receptor type III (betaglycan).


Pssm-ID: 214579  Cd Length: 252  Bit Score: 206.85  E-value: 6.28e-62
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829904633   372 ECGTADIKVSLSKCQLKSLGFEKVFMYLRDSRCSGFNERGNRDWVSVVTPAQAgpCGTVMTKNETHATYSNTLYLA---D 448
Cdd:smart00241   1 QCGEDQMVVSVSTDLLFPGGINVKGLTLGDPSCRPQFTDATSAFVSFEVPLNG--CGTRRQVNPDGIVYSNTLVVSpfhP 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829904633   449 EIIIRDRNIKINFACSYPLDMKVSLMTSLQPVVSVLNISVGgTGMFTVRMALFQSPAYTQPYQGSSVTmtTDAFLYVGII 528
Cdd:smart00241  79 GFITRDDRAAYHFQCFYPENEKVSLNLDVSTIPPTELSSVS-EGPLTCSYRLYKDDSFGSPYQSADYV--LGDPVYHEWE 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829904633   529 LDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCP--RLEDSTVQVVENGESpQSRFSVQMFRFTgNYDLVYLHCEV 606
Cdd:smart00241 156 CDGADDPPLGLLVDNCYATPGPDPSSGPKYFIIDNGCPvdGYLDSTIPYNSNPLH-RARFSVKVFKFA-DRSLVYFHCQI 233

                          250
                   ....*....|....*..
gi 829904633   607 YLCD--SVIENCKPTCS 621
Cdd:smart00241 234 RLCDkdDGSSCDGPACS 250
Zona_pellucida pfam00100
Zona pellucida-like domain;
373-621 2.67e-61

Zona pellucida-like domain;


Pssm-ID: 459673 [Multi-domain]  Cd Length: 254  Bit Score: 205.53  E-value: 2.67e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829904633  373 CGTADIKVSLSKCQLKSLGF--EKVFMYLRDSRCSGFNERGNRDWVSVVTPAQAgpCGTVMTKNETHATYSNTLYLADE- 449
Cdd:pfam00100   1 CTPDTMTVSISKCLLVPSGLlsSLSLLGGLDPSCKPVSNTNGSPAVLFEFPLTG--CGTTVQVNGTHIIYSNTLYSSTDl 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829904633  450 ---IIIRDRNIKINFACSYPLDMKVSLMTSLQPvvSVLNISVGGTGMFTVRMALFQSPAYTQPYQGSSVTMTTDAFLYVG 526
Cdd:pfam00100  79 rsgIIRRTITRRLPFSCSYPRSSLVSLLVVAPP--SPVPITVSGSGVFLVSMDLYYDSSYTSPYSPYPVTVLLGDPLYVE 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829904633  527 IILDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCPRLEDST--VQVVENGESPQSRFSVQMFRFTGNY-DLVYLH 603
Cdd:pfam00100 157 VSLLSRTDPNLVLVLDNCWATPSPNPTSSPQYQLIVNGCPNDGDSTypVSSLSNGPSHYVRFSFKAFRFVGSSiSQVYLH 236

                         250
                  ....*....|....*...
gi 829904633  604 CEVYLCDSVIENCKPTCS 621
Cdd:pfam00100 237 CSVSVCSSDSNSCGKSCS 254
EGF_3 pfam12947
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ...
 150-186 1.38e-07

EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.


Pssm-ID: 463759 [Multi-domain]  Cd Length: 36  Bit Score: 47.98  E-value: 1.38e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 829904633  150 CSEsGLSHCHALATCVNEEGSYSCVCPAGYLGDGWHC 186
Cdd:pfam12947   1 CSD-NNGGCHPNATCTNTGGSFTCTCNDGYTGDGVTC 36
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 146-187 3.54e-07

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 46.86  E-value: 3.54e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 829904633 146 DVDECSESGLshCHALATCVNEEGSYSCVCPAGYLGDgwHCE 187
Cdd:cd00054    1 DIDECASGNP--CQNGGTCVNTVGSYRCSCPPGYTGR--NCE 38
EGF_CA smart00179
Calcium-binding EGF-like domain;
146-187 4.37e-07

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.47  E-value: 4.37e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 829904633   146 DVDECSESGLshCHALATCVNEEGSYSCVCPAGYLgDGWHCE 187
Cdd:smart00179   1 DIDECASGNP--CQNGGTCVNTVGSYRCECPPGYT-DGRNCE 39
EGF_CA pfam07645
Calcium-binding EGF domain;
146-178 1.52e-06

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 44.92  E-value: 1.52e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 829904633  146 DVDECsESGLSHCHALATCVNEEGSYSCVCPAG 178
Cdd:pfam07645   1 DVDEC-ATGTHNCPANTVCVNTIGSFECRCPDG 32
EGF_CA pfam07645
Calcium-binding EGF domain;
103-135 2.33e-06

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 44.54  E-value: 2.33e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 829904633  103 DLDECAIPEvHNCSANENCVNTPGFYECVCLEG 135
Cdd:pfam07645   1 DVDECATGT-HNCPANTVCVNTIGSFECRCPDG 32
EGF_CA smart00179
Calcium-binding EGF-like domain;
103-145 2.83e-05

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 41.46  E-value: 2.83e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 829904633   103 DLDECAipEVHNCSANENCVNTPGFYECVCLEGFreTPGLGCT 145
Cdd:smart00179   1 DIDECA--SGNPCQNGGTCVNTVGSYRCECPPGY--TDGRNCE 39
EGF cd00053
Epidermal growth factor domain, found in epidermal growth factor (EGF) presents in a large ...
 149-187 1.07e-04

Epidermal growth factor domain, found in epidermal growth factor (EGF) presents in a large number of proteins, mostly animal; the list of proteins currently known to contain one or more copies of an EGF-like pattern is large and varied; the functional significance of EGF-like domains in what appear to be unrelated proteins is not yet clear; a common feature is that these repeats are found in the extracellular domain of membrane-bound proteins or in proteins known to be secreted (exception: prostaglandin G/H synthase); the domain includes six cysteine residues which have been shown to be involved in disulfide bonds; the main structure is a two-stranded beta-sheet followed by a loop to a C-terminal short two-stranded sheet; Subdomains between the conserved cysteines vary in length; the region between the 5th and 6th cysteine contains two conserved glycines of which at least one is present in most EGF-like domains; a subset of these bind calcium.


Pssm-ID: 238010  Cd Length: 36  Bit Score: 39.77  E-value: 1.07e-04
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 829904633 149 ECSESGLshCHALATCVNEEGSYSCVCPAGYLGDGwHCE 187
Cdd:cd00053    1 ECAASNP--CSNGGTCVNTPGSYRCVCPPGYTGDR-SCE 36
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 103-137 1.84e-04

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 39.16  E-value: 1.84e-04
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 829904633 103 DLDECAIPevHNCSANENCVNTPGFYECVCLEGFR 137
Cdd:cd00054    1 DIDECASG--NPCQNGGTCVNTVGSYRCSCPPGYT 33
EGF_3 pfam12947
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ...
 72-101 6.43e-04

EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.


Pssm-ID: 463759 [Multi-domain]  Cd Length: 36  Bit Score: 37.58  E-value: 6.43e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 829904633   72 DCHSNATCMEDGVVTTCFCQEGFTGDGLTC 101
Cdd:pfam12947   7 GCHPNATCTNTGGSFTCTCNDGYTGDGVTC 36
EGF_3 pfam12947
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ...
 113-137 3.71e-03

EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.


Pssm-ID: 463759 [Multi-domain]  Cd Length: 36  Bit Score: 35.65  E-value: 3.71e-03
                          10        20
                  ....*....|....*....|....*
gi 829904633  113 HNCSANENCVNTPGFYECVCLEGFR 137
Cdd:pfam12947   6 GGCHPNATCTNTGGSFTCTCNDGYT 30
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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