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Conserved domains on  [gi|826327431|ref|XP_012511666|]
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PREDICTED: ubiquinone biosynthesis monooxygenase COQ6, mitochondrial isoform X2 [Propithecus coquereli]

Protein Classification

Rossmann-fold NAD(P)-binding domain-containing protein( domain architecture ID 229380)

Rossmann-fold NAD(P)-binding domain-containing protein may function as an oxidoreductase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NADB_Rossmann super family cl21454
Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a ...
 48-463 0e+00

Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The NADB domain is found in numerous dehydrogenases of metabolic pathways such as glycolysis, and many other redox enzymes. NAD binding involves numerous hydrogen-bonds and van der Waals contacts, in particular H-bonding of residues in a turn between the first strand and the subsequent helix of the Rossmann-fold topology. Characteristically, this turn exhibits a consensus binding pattern similar to GXGXXG, in which the first 2 glycines participate in NAD(P)-binding, and the third facilitates close packing of the helix to the beta-strand. Typically, proteins in this family contain a second domain in addition to the NADB domain, which is responsible for specifically binding a substrate and catalyzing a particular enzymatic reaction.


The actual alignment was detected with superfamily member TIGR01989:

Pssm-ID: 473865 [Multi-domain]  Cd Length: 437  Bit Score: 647.20  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431   48 AAMACALGHDIHFCDKKILLLEAG--PKK---VLEKLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWD 122
Cdd:TIGR01989  13 LALAAALGNNPLTKDLKVLLLDAVdnPKLksrNYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSDRIQPFGRMQVWD 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  123 ACSEALIMFDKDN-LDDMGYIVENDVIMHALTKQLEAV-SDRVTVLYRSRAVGYTWP--CPftmKDSSPWVHITLGDGST 198
Cdd:TIGR01989  93 GCSLALIRFDRDNgKEDMACIIENDNIQNSLYNRLQEYnGDNVKILNPARLISVTIPskYP---NDNSNWVHITLSDGQV 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  199 LQTKLLIGADGHNSGVRQAAGIQNVSWNYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHA 278
Cdd:TIGR01989 170 LYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNNSTLVWSTSPEEA 249

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  279 AELVSMDEEKFVDAINSAF---WNDANHTDFIDSAGTMLQYAISLLKPTKVSARQLPPSVASVEAKSRVLFPLGLGHAAE 355
Cdd:TIGR01989 250 LRLLSLPPEDFVDALNAAFdlgYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSRAAFPLGLGHADE 329

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  356 YVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLSTAAFNGRDLGSMNHLTGYETDRQRHNTALLAATDLLKRLYS 435
Cdd:TIGR01989 330 YVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVLLGLVDKLHKLYA 409

                         410       420
                  ....*....|....*....|....*...
gi 826327431  436 TNATPLVLLRTWGLQATNAVSPLKEQIM 463
Cdd:TIGR01989 410 TDFPPVVALRTFGLNLTNYIGPLKNFIM 437
 
Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 48-463 0e+00

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 647.20  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431   48 AAMACALGHDIHFCDKKILLLEAG--PKK---VLEKLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWD 122
Cdd:TIGR01989  13 LALAAALGNNPLTKDLKVLLLDAVdnPKLksrNYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSDRIQPFGRMQVWD 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  123 ACSEALIMFDKDN-LDDMGYIVENDVIMHALTKQLEAV-SDRVTVLYRSRAVGYTWP--CPftmKDSSPWVHITLGDGST 198
Cdd:TIGR01989  93 GCSLALIRFDRDNgKEDMACIIENDNIQNSLYNRLQEYnGDNVKILNPARLISVTIPskYP---NDNSNWVHITLSDGQV 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  199 LQTKLLIGADGHNSGVRQAAGIQNVSWNYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHA 278
Cdd:TIGR01989 170 LYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNNSTLVWSTSPEEA 249

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  279 AELVSMDEEKFVDAINSAF---WNDANHTDFIDSAGTMLQYAISLLKPTKVSARQLPPSVASVEAKSRVLFPLGLGHAAE 355
Cdd:TIGR01989 250 LRLLSLPPEDFVDALNAAFdlgYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSRAAFPLGLGHADE 329

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  356 YVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLSTAAFNGRDLGSMNHLTGYETDRQRHNTALLAATDLLKRLYS 435
Cdd:TIGR01989 330 YVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVLLGLVDKLHKLYA 409

                         410       420
                  ....*....|....*....|....*...
gi 826327431  436 TNATPLVLLRTWGLQATNAVSPLKEQIM 463
Cdd:TIGR01989 410 TDFPPVVALRTFGLNLTNYIGPLKNFIM 437
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 77-466 1.01e-74

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 240.44  E-value: 1.01e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  77 EKLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDACSEALIMFDKDNL--DDMGYIVENDVIMHALtk 154
Cdd:PRK08850  40 EALNELPDVRVSALSRSSEHILRNLGAWQGIEARRAAPYIAMEVWEQDSFARIEFDAESMaqPDLGHIVENRVIQLAL-- 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 155 qLEAVS--DRVTVLYRSR----AVGytwpcpftmkDSSPWvhITLGDGSTLQTKLLIGADGHNSGVRQAAGIQNVSWNYD 228
Cdd:PRK08850 118 -LEQVQkqDNVTLLMPARcqsiAVG----------ESEAW--LTLDNGQALTAKLVVGADGANSWLRRQMDIPLTHWDYG 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 229 QSAVVATLHLSEaTENNVAWQRFLPSGPIALLPLSDT-LSSLVWSTSHEHAAELVSMDEEKFVDAINSAFWNdanhtdfi 307
Cdd:PRK08850 185 HSALVANVRTVD-PHNSVARQIFTPQGPLAFLPMSEPnMSSIVWSTEPLRAEALLAMSDEQFNKALTAEFDN-------- 255

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 308 dsagtmlqyaisllkptkvsarQLppSVASVEAkSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDIS 387
Cdd:PRK08850 256 ----------------------RL--GLCEVVG-ERQAFPLKMRYARDFVRERVALVGDAAHTIHPLAGQGVNLGLLDAA 310

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 826327431 388 SLVHHLSTAAFNGRDLGSMNHLTGYETDRQRHNTALLAATDLLKRLYSTNATPLVLLRTWGLQATNAVSPLKEQIMAFA 466
Cdd:PRK08850 311 SLAQEILALWQQGRDIGLKRNLRGYERWRKAEAAKMIAAMQGFRDLFSGSNPAKKLVRGIGMSLAGQLPGAKDEIMKRA 389
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 48-459 7.12e-41

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 148.93  E-value: 7.12e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  48 AAMACAL---GHDIHfcdkkillleagpkkVLEKLSETYSN-RVSSISPGSATLLSSFGAWDHICnMRYRAFRRMQVWDA 123
Cdd:COG0654   16 LALALALaraGIRVT---------------VVERAPPPRPDgRGIALSPRSLELLRRLGLWDRLL-ARGAPIRGIRVRDG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 124 CS-EALIMFD-KDNLDDMGYIVENDVIMHALTKQLEAvsDRVTVLYRSRAVGYTWpcpftmkDSSPwVHITLGDGSTLQT 201
Cdd:COG0654   80 SDgRVLARFDaAETGLPAGLVVPRADLERALLEAARA--LGVELRFGTEVTGLEQ-------DADG-VTVTLADGRTLRA 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 202 KLLIGADGHNSGVRQAAGIQNVSWNYDQSAVVATLHlseatennVAWQRFLpsgpiallplsdtlsslvwstshehaael 281
Cdd:COG0654  150 DLVVGADGARSAVRRLLGIGFTGRDYPQRALWAGVR--------TELRARL----------------------------- 192

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 282 vsmdeekfvdainsafwndanhtdfidsagtmlqyaisllkptkvsaRQLPPSVASV-EAKSRVLFPLGLGHAAEYVRPR 360
Cdd:COG0654  193 -----------------------------------------------AAAGPRLGELlELSPRSAFPLRRRRAERWRRGR 225

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 361 VALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLStAAFNGRDLGSMnhLTGYETDRQRHNTALLAATDLLKRLYSTNATP 440
Cdd:COG0654  226 VVLLGDAAHTMHPLGGQGANLALRDAAALAWKLA-AALRGRDDEAA--LARYERERRPRAARVQRAADALGRLFHPDSPP 302

                        410
                 ....*....|....*....
gi 826327431 441 LVLLRTWGLQATNAVSPLK 459
Cdd:COG0654  303 LRLLRNAGLRLLDRLPPLK 321
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 194-427 7.42e-09

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 57.34  E-value: 7.42e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  194 GDGSTLQTKLLIGADGHNSGVRQAAGIQNVSWNYDQSAVVATLHLS------EATENNVAWQRFLPSGPIALLPLSDTLS 267
Cdd:pfam01494 143 GEEYTVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLFDApdlsdpVERAFVHYLIYAPHSRGFMVGPWRSAGR 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  268 S---LVWSTSHEHAAELVSMDEEKFVDAINSAFwndanHTDFIDsagtmlqyaislLKPTKVSArqlppsvasVEAKSRV 344
Cdd:pfam01494 223 EryyVQVPWDEEVEERPEEFTDEELKQRLRSIV-----GIDLAL------------VEILWKSI---------WGVASRV 276

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  345 lfplglghAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLStAAFNGRdlGSMNHLTGYETDRQRHNTALL 424
Cdd:pfam01494 277 --------ATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLAWKLA-AVLRGQ--AGESLLDTYSAERLPVAWAVV 345


                  ...
gi 826327431  425 AAT 427
Cdd:pfam01494 346 DFA 348
 
Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 48-463 0e+00

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 647.20  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431   48 AAMACALGHDIHFCDKKILLLEAG--PKK---VLEKLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWD 122
Cdd:TIGR01989  13 LALAAALGNNPLTKDLKVLLLDAVdnPKLksrNYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSDRIQPFGRMQVWD 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  123 ACSEALIMFDKDN-LDDMGYIVENDVIMHALTKQLEAV-SDRVTVLYRSRAVGYTWP--CPftmKDSSPWVHITLGDGST 198
Cdd:TIGR01989  93 GCSLALIRFDRDNgKEDMACIIENDNIQNSLYNRLQEYnGDNVKILNPARLISVTIPskYP---NDNSNWVHITLSDGQV 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  199 LQTKLLIGADGHNSGVRQAAGIQNVSWNYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHA 278
Cdd:TIGR01989 170 LYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNNSTLVWSTSPEEA 249

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  279 AELVSMDEEKFVDAINSAF---WNDANHTDFIDSAGTMLQYAISLLKPTKVSARQLPPSVASVEAKSRVLFPLGLGHAAE 355
Cdd:TIGR01989 250 LRLLSLPPEDFVDALNAAFdlgYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSRAAFPLGLGHADE 329

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  356 YVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLSTAAFNGRDLGSMNHLTGYETDRQRHNTALLAATDLLKRLYS 435
Cdd:TIGR01989 330 YVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVLLGLVDKLHKLYA 409

                         410       420
                  ....*....|....*....|....*...
gi 826327431  436 TNATPLVLLRTWGLQATNAVSPLKEQIM 463
Cdd:TIGR01989 410 TDFPPVVALRTFGLNLTNYIGPLKNFIM 437
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 48-467 7.16e-154

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 442.03  E-value: 7.16e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431   48 AAMACALGHDIhfcdKKILLLEAGPKKVLEklSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDACSEA 127
Cdd:TIGR01988  12 LALALALARSG----LKVALIEATPLPAPA--DPGFDNRVSALSAASIRLLEKLGVWDKIEPARAQPIRDIHVSDGGSFG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  128 LIMFDKD--NLDDMGYIVENDVIMHALTKQLEAVSdrvtvlyrsravGYTWPCPF---TMKDSSPWVHITLGDGSTLQTK 202
Cdd:TIGR01988  86 ALRFDADeiGLEALGYVVENRVLQQALWERLQELP------------NVTLLCPArvvELPRHSDHVELTLDDGQQLRAR 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  203 LLIGADGHNSGVRQAAGIQNVSWNYDQSAVVATLHLSEATeNNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELV 282
Cdd:TIGR01988 154 LLVGADGANSKVRQLAGIPTTGWDYGQSAVVANVKHERPH-QGTAWERFTPTGPLALLPLPDNRSSLVWTLPPEEAERLL 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  283 SMDEEKFVDAINSAFWNDanhtdfidsAGTMLQyaisllkptkvsarqlppsvasveAKSRVLFPLGLGHAAEYVRPRVA 362
Cdd:TIGR01988 233 ALSDEEFLAELQRAFGSR---------LGAITL------------------------VGERHAFPLSLTHAKRYVAPRLA 279

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  363 LIGDAAHRVHPLAGQGVNMGFGDISSLVHHLSTAAFNGRDLGSMNHLTGYETDRQRHNTALLAATDLLKRLYSTNATPLV 442
Cdd:TIGR01988 280 LIGDAAHTIHPLAGQGLNLGLRDVAALAEVLEDARRRGEDIGSLRVLQRYERRRRFDNAAMLGATDGLNRLFSNDFPPLR 359

                         410       420
                  ....*....|....*....|....*
gi 826327431  443 LLRTWGLQATNAVSPLKEQIMAFAS 467
Cdd:TIGR01988 360 LLRNLGLRLLNNLPPLKNFIARYAM 384
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 77-466 1.01e-74

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 240.44  E-value: 1.01e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  77 EKLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDACSEALIMFDKDNL--DDMGYIVENDVIMHALtk 154
Cdd:PRK08850  40 EALNELPDVRVSALSRSSEHILRNLGAWQGIEARRAAPYIAMEVWEQDSFARIEFDAESMaqPDLGHIVENRVIQLAL-- 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 155 qLEAVS--DRVTVLYRSR----AVGytwpcpftmkDSSPWvhITLGDGSTLQTKLLIGADGHNSGVRQAAGIQNVSWNYD 228
Cdd:PRK08850 118 -LEQVQkqDNVTLLMPARcqsiAVG----------ESEAW--LTLDNGQALTAKLVVGADGANSWLRRQMDIPLTHWDYG 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 229 QSAVVATLHLSEaTENNVAWQRFLPSGPIALLPLSDT-LSSLVWSTSHEHAAELVSMDEEKFVDAINSAFWNdanhtdfi 307
Cdd:PRK08850 185 HSALVANVRTVD-PHNSVARQIFTPQGPLAFLPMSEPnMSSIVWSTEPLRAEALLAMSDEQFNKALTAEFDN-------- 255

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 308 dsagtmlqyaisllkptkvsarQLppSVASVEAkSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDIS 387
Cdd:PRK08850 256 ----------------------RL--GLCEVVG-ERQAFPLKMRYARDFVRERVALVGDAAHTIHPLAGQGVNLGLLDAA 310

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 826327431 388 SLVHHLSTAAFNGRDLGSMNHLTGYETDRQRHNTALLAATDLLKRLYSTNATPLVLLRTWGLQATNAVSPLKEQIMAFA 466
Cdd:PRK08850 311 SLAQEILALWQQGRDIGLKRNLRGYERWRKAEAAKMIAAMQGFRDLFSGSNPAKKLVRGIGMSLAGQLPGAKDEIMKRA 389
PRK07364 PRK07364
FAD-dependent hydroxylase;
48-459 1.21e-70

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 229.91  E-value: 1.21e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  48 AAMACALGHDihfcDKKILLLEAGPKKVLEKLSETYSnrvssISPGSATLLSSFGAWDHICNmRYRAFRRMQVWDACSEA 127
Cdd:PRK07364  31 LTLAAALKDS----GLRIALIEAQPAEAAAAKGQAYA-----LSLLSARIFEGIGVWEKILP-QIGKFRQIRLSDADYPG 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 128 LIMFDKDNL--DDMGYIVENDVIMHALTKQLEAvSDRVTvlyrsravgytWPCP-----FTMKDSSPWVHITLGDGS-TL 199
Cdd:PRK07364 101 VVKFQPTDLgtEALGYVGEHQVLLEALQEFLQS-CPNIT-----------WLCPaevvsVEYQQDAATVTLEIEGKQqTL 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 200 QTKLLIGADGHNSGVRQAAGIQNVSWNYDQSAVVATLHLsEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAA 279
Cdd:PRK07364 169 QSKLVVAADGARSPIRQAAGIKTKGWKYWQSCVTATVKH-EAPHNDIAYERFWPSGPFAILPLPGNRCQIVWTAPHAQAK 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 280 ELVSMDEEKFVDainsafwndanhtdfidsagTMLQYAISLL-KPTKVSARQlppsvasveaksrvLFPLGLGHAAEYVR 358
Cdd:PRK07364 248 ALLALPEAEFLA--------------------ELQQRYGDQLgKLELLGDRF--------------LFPVQLMQSDRYVQ 293

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 359 PRVALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLSTAAFNGRDLGSMNHLTGYETDRQRHNTALLAATDLLKRLYSTNA 438
Cdd:PRK07364 294 HRLALVGDAAHCCHPVGGQGLNLGIRDAAALAQVLQTAHQRGEDIGSLAVLKRYERWRKRENWLILGFTDLLDRLFSNQW 373

                        410       420
                 ....*....|....*....|.
gi 826327431 439 TPLVLLRTWGLQATNAVSPLK 459
Cdd:PRK07364 374 WPLVVVRRLGLWLLRHVPPLK 394
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
48-467 3.59e-70

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 227.91  E-value: 3.59e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  48 AAMACALGHDihfcDKKILLLEAGPkkVLEKLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVW-DAcsE 126
Cdd:PRK07608  18 ASLALALAQS----GLRVALLAPRA--PPRPADDAWDSRVYAISPSSQAFLERLGVWQALDAARLAPVYDMRVFgDA--H 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 127 ALIMFD--KDNLDDMGYIVENDVIMHALTKQLeAVSDRVTVLyRSRAVGytwpcpFTMKDSSpwVHITLGDGSTLQTKLL 204
Cdd:PRK07608  90 ARLHFSayQAGVPQLAWIVESSLIERALWAAL-RFQPNLTWF-PARAQG------LEVDPDA--ATLTLADGQVLRADLV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 205 IGADGHNSGVRQAAGIQNVSWNYDQSAVVATLhLSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSM 284
Cdd:PRK07608 160 VGADGAHSWVRSQAGIKAERRPYRQTGVVANF-KAERPHRGTAYQWFRDDGILALLPLPDGHVSMVWSARTAHADELLAL 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 285 DEEKFVDAINSAfwndANHTdfidsAGTMlqyaisllkptkvsaRQLPPSVAsveaksrvlFPLGLGHAAEYVRPRVALI 364
Cdd:PRK07608 239 SPEALAARVERA----SGGR-----LGRL---------------ECVTPAAG---------FPLRLQRVDRLVAPRVALV 285

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 365 GDAAHRVHPLAGQGVNMGFGDISSLVHHL-STAAFngRDLGSMNHLTGYETDRQRHNTALLAATDLLKRLYSTNATPLVL 443
Cdd:PRK07608 286 GDAAHLIHPLAGQGMNLGLRDVAALADVLaGREPF--RDLGDLRLLRRYERARREDILALQVATDGLQRLFALPGPLARW 363

                        410       420
                 ....*....|....*....|....
gi 826327431 444 LRTWGLQATNAVSPLKEQIMAFAS 467
Cdd:PRK07608 364 LRNAGMALVGALPLVKRWLVRHAL 387
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 86-466 5.59e-69

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 224.86  E-value: 5.59e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  86 RVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDACSeALIMFDKD--NLDDMGYIVENDVIMHALTKQLEAVSDrV 163
Cdd:PRK08020  51 RISAISAASVALLKGLGVWDAVQAMRSHPYRRLETWEWET-AHVVFDAAelKLPELGYMVENRVLQLALWQALEAHPN-V 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 164 TVLyrsravgytwpCPFTMKDSSP----WvHITLGDGSTLQTKLLIGADGHNSGVRQAAGIQNVSWNYDQSAVVATLHlS 239
Cdd:PRK08020 129 TLR-----------CPASLQALQRdddgW-ELTLADGEEIQAKLVIGADGANSQVRQMAGIGVHGWQYRQSCMLISVK-C 195

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 240 EATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAINSAFwndanhtdfidsagtmlqyais 319
Cdd:PRK08020 196 ENPPGDSTWQQFTPSGPRAFLPLFDNWASLVWYDSPARIRQLQAMSMAQLQQEIAAHF---------------------- 253

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 320 llkPTKVSArqlppsVASVEAKSrvlFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLSTAAFN 399
Cdd:PRK08020 254 ---PARLGA------VTPVAAGA---FPLTRRHALQYVQPGLALVGDAAHTINPLAGQGVNLGYRDVDALLDVLVNARSY 321

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 826327431 400 GRDLGSMNHLTGYETDRQRHNTALLAATDLLKRLYSTNATPLVLLRTWGLQATNAVSPLKEQIMAFA 466
Cdd:PRK08020 322 GEAWASEAVLKRYQRRRMADNLLMQSGMDLFYAGFSNNLPPLRFARNLGLMAAQRAGVLKRQALKYA 388
PRK05714 PRK05714
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 48-459 3.09e-66

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 168201 [Multi-domain]  Cd Length: 405  Bit Score: 218.16  E-value: 3.09e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  48 AAMACALGHDihfcDKKILLLEAGPKKVLE-KLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDACSE 126
Cdd:PRK05714  15 SALALALQGS----GLEVLLLDGGPLSVKPfDPQAPFEPRVSALSAASQRILERLGAWDGIAARRASPYSEMQVWDGSGT 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 127 ALIMFDKDNL--DDMGYIVENDVIMHALTKQLEAvSDrVTVLYRSRAVGytwpcpftMKDSSPWVHITLGDGSTLQTKLL 204
Cdd:PRK05714  91 GQIHFSAASVhaEVLGHIVENRVVQDALLERLHD-SD-IGLLANARLEQ--------MRRSGDDWLLTLADGRQLRAPLV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 205 IGADGHNSGVRQAAGIQNVSWNYDQSAVVATLHLSEAtENNVAWQRFLPSGPIALLPLSDT----LSSLVWSTSHEHAAE 280
Cdd:PRK05714 161 VAADGANSAVRRLAGCATREWDYLHHAIVTSVRCSEP-HRATAWQRFTDDGPLAFLPLERDgdehWCSIVWSTTPEEAER 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 281 LVSMDEEKFVDAINSAFWNDANHTdfidsagtmlqyaisllkptkvsarqlppsvasVEAKSRVLFPLGLGHAAEYVRPR 360
Cdd:PRK05714 240 LMALDDDAFCAALERAFEGRLGEV---------------------------------LSADPRLCVPLRQRHAKRYVEPG 286

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 361 VALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLSTAAFNGRDLGSMNHLTGYETDRQRHNTALLAATDLLKRLYSTNATP 440
Cdd:PRK05714 287 LALIGDAAHTIHPLAGQGVNLGFLDAAVLAEVLLHAAERGERLADVRVLSRFERRRMPHNLALMAAMEGFERLFQADPLP 366

                        410
                 ....*....|....*....
gi 826327431 441 LVLLRTWGLQATNAVSPLK 459
Cdd:PRK05714 367 LRWLRNTGLKLVDQMPEAK 385
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
62-460 6.66e-66

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 217.15  E-value: 6.66e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  62 DKKILLLEAGPKKVLEKlsetySNRVSSISPGSATLLSSFGAWDHICNmRYRAFRRMQVWDACSE-----ALIMFDKDNL 136
Cdd:PRK07333  26 HLPVTVVDAAPAGAWSR-----DPRASAIAAAARRMLEALGVWDEIAP-EAQPITDMVITDSRTSdpvrpVFLTFEGEVE 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 137 DD--MGYIVENDVIMHALTKQLEAVSdrVTVLYRSRAVGytwpcpFTMKDSSpwVHITLGDGSTLQTKLLIGADGHNSGV 214
Cdd:PRK07333 100 PGepFAHMVENRVLINALRKRAEALG--IDLREATSVTD------FETRDEG--VTVTLSDGSVLEARLLVAADGARSKL 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 215 RQAAGIQNVSWNYDQSAVVATL-HlsEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAI 293
Cdd:PRK07333 170 RELAGIKTVGWDYGQSGIVCTVeH--ERPHGGRAEEHFLPAGPFAILPLKGNRSSLVWTERTADAERLVALDDLVFEAEL 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 294 NSAFwndanhtdfidsaGtmlqyaislLKPTKVsarqlppsvaSVEAKSRVlFPLGLGHAAEYVRPRVALIGDAAHRVHP 373
Cdd:PRK07333 248 EQRF-------------G---------HRLGEL----------KVLGKRRA-FPLGLTLARSFVAPRFALVGDAAHGIHP 294

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 374 LAGQGVNMGFGDISSLVHHLSTAAFNGRDLGSMNHLTGYETDRQRHNTALLAATDLLKRLYSTNATPLVLLRTWGLQATN 453
Cdd:PRK07333 295 IAGQGLNLGLKDVAALAEVVVEAARLGLDIGSLDVLERYQRWRRFDTVRMGVTTDVLNRLFSNDSTLLRSVRDIGLGLVD 374


                 ....*..
gi 826327431 454 AVSPLKE 460
Cdd:PRK07333 375 RLPKLKS 381
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 63-466 4.57e-64

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 211.94  E-value: 4.57e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  63 KKILLLEAGPKKVLEKlSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDAcSEALIMFDKD--NLDDMG 140
Cdd:PRK08849  27 RSVAVIEGGEPKAFEP-SQPMDIRVSAISQTSVDLLESLGAWSSIVAMRVCPYKRLETWEH-PECRTRFHSDelNLDQLG 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 141 YIVENDVIMHALTKQLEAVsDRVTVLyrsravgytwpCPFTMKD---SSPWVHITLGDGSTLQTKLLIGADGHNSGVRQA 217
Cdd:PRK08849 105 YIVENRLIQLGLWQQFAQY-PNLTLM-----------CPEKLADlefSAEGNRVTLESGAEIEAKWVIGADGANSQVRQL 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 218 AGIQNVSWNYDQSAVVATLHlSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAInsaf 297
Cdd:PRK08849 173 AGIGITAWDYRQHCMLINVE-TEQPQQDITWQQFTPSGPRSFLPLCGNQGSLVWYDSPKRIKQLSAMNPEQLRSEI---- 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 298 wndanhtdfidsagtmlqyaisllkptkvsARQLPPSVASVEAKSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQ 377
Cdd:PRK08849 248 ------------------------------LRHFPAELGEIKVLQHGSFPLTRRHAQQYVKNNCVLLGDAAHTINPLAGQ 297

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 378 GVNMGFGDISSLVHhlstaAFNGRDLGSMNHLTGYETDRQRHNTALLAATDLLKRLYSTNATPLVLLRTWGLQATNAVSP 457
Cdd:PRK08849 298 GVNLGFKDVDVLLA-----ETEKQGVLNDASFARYERRRRPDNLLMQTGMDLFYKTFSNSLTPLKFVRNAALKLAENSGP 372


                 ....*....
gi 826327431 458 LKEQIMAFA 466
Cdd:PRK08849 373 LKTQVLKYA 381
UbiH TIGR01984
2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent ...
 48-462 2.28e-63

2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent monoxygenase responsible for the second hydroxylation step in the aerobic ubiquinone bioynthetic pathway. The scope of this model is limited to the proteobacteria. This family is closely related to the UbiF hydroxylase which catalyzes the final hydroxylation step. The enzyme has also been named VisB due to a mutant VISible light sensitive phenotype. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273911 [Multi-domain]  Cd Length: 382  Bit Score: 209.86  E-value: 2.28e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431   48 AAMACALGHDihfCDKKILLLEAgpkKVLEKLSETYSNRVSSISPGSATLLSSFGAWDHICNmRYRAFRRMQVWDACSEA 127
Cdd:TIGR01984  12 LSLALALSRL---GKIKIALIEA---NSPSAAQPGFDARSLALSYGSKQILEKLGLWPKLAP-FATPILDIHVSDQGHFG 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  128 LIMFDKD--NLDDMGYIVENDVIMHALTKQLeavsDRVTVLyrsravgyTWPCPFTMKDSSP---WVHITLGDGSTLQTK 202
Cdd:TIGR01984  85 ATHLRASefGLPALGYVVELADLGQALLSRL----ALLTNI--------QLYCPARYKEIIRnqdYVRVTLDNGQQLRAK 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  203 LLIGADGHNSGVRQAAGIQNVSWNYDQSAVVATLHLSEATENnVAWQRFLPSGPIALLPLSD-TLSSLVWSTSHEHAAEL 281
Cdd:TIGR01984 153 LLIAADGANSKVRELLSIPTEEHDYNQTALIANIRHEQPHQG-CAFERFTPHGPLALLPLKDnYRSSLVWCLPSKQADTI 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  282 VSMDEEKFVDAINSAFWNDANhtdfidsagtmlqyaisllKPTKVSARQLppsvasveaksrvlFPLGLGHAAEYVRPRV 361
Cdd:TIGR01984 232 ANLPDAEFLAELQQAFGWRLG-------------------KITQVGERKT--------------YPLKLRIAETHVHPRV 278

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  362 ALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLSTAAfngRDLGSMNHLTGYETDRQRHNTALLAATDLLKRLYSTNATPL 441
Cdd:TIGR01984 279 VLIGNAAQTLHPIAGQGFNLGLRDVETLAEVLIDAR---IDLGTYALLQEYLRRRQFDQFITIGLTDGLNRLFSNHIPLL 355

                         410       420
                  ....*....|....*....|.
gi 826327431  442 VLLRTWGLQATNAVSPLKEQI 462
Cdd:TIGR01984 356 RALRNLGLLALENFPPLKKRL 376
PRK08013 PRK08013
oxidoreductase; Provisional
 49-463 3.33e-61

oxidoreductase; Provisional


Pssm-ID: 236139 [Multi-domain]  Cd Length: 400  Bit Score: 204.89  E-value: 3.33e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  49 AMACALghdiHFCDKKILLLEAGPKKVLEkLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDACSEAL 128
Cdd:PRK08013  17 AVACGL----QGSGLRVAVLEQRVPEPLA-ADAPPALRVSAINAASEKLLTRLGVWQDILARRASCYHGMEVWDKDSFGR 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 129 IMFDKDN--LDDMGYIVENDVIMHALTKQLEAVSDrVTVLyrsravgytwpCPFTMKDSSpW----VHITLGDGSTLQTK 202
Cdd:PRK08013  92 IAFDDQSmgYSHLGHIIENSVIHYALWQKAQQSSD-ITLL-----------APAELQQVA-WgeneAFLTLKDGSMLTAR 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 203 LLIGADGHNSGVRQAAGIQNVSWNYDQSAVVATLHLSEAtENNVAWQRFLPSGPIALLPLSD-TLSSLVWSTSHEHAAEL 281
Cdd:PRK08013 159 LVVGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEP-HDAVARQVFHGDGILAFLPLSDpHLCSIVWSLSPEEAQRM 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 282 VSMDEEKFVDAINSAFWNdanhtdfidsagtmlqyaiSLLKPTKVSARQlppsvasveaksrvLFPLGLGHAAEYVRPRV 361
Cdd:PRK08013 238 QQAPEEEFNRALAIAFDN-------------------RLGLCELESERQ--------------VFPLTGRYARQFAAHRL 284

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 362 ALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLSTAAFNGRDLGSMNHLTGYETDRQRHNTALLAATDLLKRLYSTNATPL 441
Cdd:PRK08013 285 ALVGDAAHTIHPLAGQGVNLGFMDAAELIAELRRLHRQGKDIGQHLYLRRYERSRKHSAALMLAGMQGFRDLFAGNNPAK 364

                        410       420
                 ....*....|....*....|..
gi 826327431 442 VLLRTWGLQATNAVSPLKEQIM 463
Cdd:PRK08013 365 KLLRDIGLKLADTLPGVKPQLI 386
PRK08773 PRK08773
UbiH/UbiF family hydroxylase;
86-458 7.43e-58

UbiH/UbiF family hydroxylase;


Pssm-ID: 181552 [Multi-domain]  Cd Length: 392  Bit Score: 195.85  E-value: 7.43e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  86 RVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDACSEALIMFDKDNL--DDMGYIVENDVIMHALTKQLEAVsdrv 163
Cdd:PRK08773  51 RVYAFAADNAALLDRLGVWPAVRAARAQPYRRMRVWDAGGGGELGFDADTLgrEQLGWIVENDLLVDRLWAALHAA---- 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 164 tvlyrsravGYTWPCP---FTMKDSSPWVHITLGDGSTLQTKLLIGADGHNSGVRQAAGIQNVSWNYDQSAVVA---TLH 237
Cdd:PRK08773 127 ---------GVQLHCParvVALEQDADRVRLRLDDGRRLEAALAIAADGAASTLRELAGLPVSRHDYAQRGVVAfvdTEH 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 238 LSEATennvAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAINSAFwndanhtdfidsagtmlqya 317
Cdd:PRK08773 198 PHQAT----AWQRFLPTGPLALLPFADGRSSIVWTLPDAEAERVLALDEAAFSRELTQAF-------------------- 253

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 318 isllkptkvSARQLPPSVASveakSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLSTAA 397
Cdd:PRK08773 254 ---------AARLGEVRVAS----PRTAFPLRRQLVQQYVSGRVLTLGDAAHVVHPLAGQGVNLGLRDVAALQQLVRQAH 320

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 826327431 398 FNGRDLGSMNHLTGYETDRQRHNTALLAATDLLKRLYSTNATPLVLLRTWGLQATNAVSPL 458
Cdd:PRK08773 321 ARRADWAAPHRLQRWARTRRSDNTVAAYGFDAINRVFSNDEMHLTLLRGSVLGLAGKLPPL 381
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 83-459 7.84e-56

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 190.45  E-value: 7.84e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  83 YSNRVSSISPGSATLLSSFGAWDHIcNMRYRAFRRMQVWDACSEALIMFDKD--NLDDMGYIVENdvimHALTKQLEAVS 160
Cdd:PRK05732  48 FDARAIALAAGTCQQLARLGVWQAL-ADCATPITHIHVSDRGHAGFVRLDAEdyGVPALGYVVEL----HDVGQRLFALL 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 161 DRvtvlyrsrAVGYTWPCPFTMKDSSP---WVHITLGDGSTLQTKLLIGADGHNSGVRQAAGIQNVSWNYDQSAVVATLH 237
Cdd:PRK05732 123 DK--------APGVTLHCPARVANVERtqgSVRVTLDDGETLTGRLLVAADGSHSALREALGIDWQQHPYEQVAVIANVT 194

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 238 LSEAtENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAINSAF-WNdanhtdfidsAGTMlqy 316
Cdd:PRK05732 195 TSEA-HQGRAFERFTEHGPLALLPMSDGRCSLVWCHPLEDAEEVLSWSDAQFLAELQQAFgWR----------LGRI--- 260

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 317 aisllkpTKVSARQlppsvasveaksrvLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLSTA 396
Cdd:PRK05732 261 -------THAGKRS--------------AYPLALVTAAQQISHRLALVGNAAQTLHPIAGQGFNLGLRDVMSLAETLTQA 319

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 826327431 397 AFNGRDLGSMNHLTGYETDRQ--RHNTalLAATDLLKRLYSTNATPLVLLRTWGLQATNAVSPLK 459
Cdd:PRK05732 320 LARGEDIGDYAVLQRYQQRRQqdREAT--IGFTDGLVRLFANRWAPLVVGRNLGLMAMDLLPPAR 382
PRK09126 PRK09126
FAD-dependent hydroxylase;
64-462 3.64e-44

FAD-dependent hydroxylase;


Pssm-ID: 236385 [Multi-domain]  Cd Length: 392  Bit Score: 159.34  E-value: 3.64e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  64 KILLLEAGPKKVLEklSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDACSEALIMFDKDN--LDDMGY 141
Cdd:PRK09126  28 KVTLIERQPLAALA--DPAFDGREIALTHASREILQRLGAWDRIPEDEISPLRDAKVLNGRSPFALTFDARGrgADALGY 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 142 IVENDVIMHALtkqLEAVSDRVTV-LYRSRAVGytwpcpfTMKDSSPWVHITLGDGSTLQTKLLIGADGHNSGVRQAAGI 220
Cdd:PRK09126 106 LVPNHLIRRAA---YEAVSQQDGIeLLTGTRVT-------AVRTDDDGAQVTLANGRRLTARLLVAADSRFSATRRQLGI 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 221 QNVSWNYDQSAVVATLHlSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAINSAFWnd 300
Cdd:PRK09126 176 GADMHDFGRTMLVCRMR-HELPHHHTAWEWFGYGQTLALLPLNGHLSSLVLTLPPDQIEALLALDPEAFAAEVTARFK-- 252

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 301 anhtdfiDSAGTMlqyaisllkpTKVSARQLPPSVASveaksrvlfplglgHAAEYVRPRVALIGDAAHRVHPLAGQGVN 380
Cdd:PRK09126 253 -------GRLGAM----------RLVSSRHAYPLVAV--------------YAHRFVAKRFALIGDAAVGMHPVTAHGFN 301

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 381 MGFGDISSLVHHLSTAAFNGRDLGSMNHLTGYETDRQRHNTALLAATDLLKRLYSTNATPLVLLRTWGLQATNAVSPLKE 460
Cdd:PRK09126 302 LGLKGQDILARLILAAARRGQDIGAASLLERYERKHRLATRPLYHATNAIAALYTDDRPPARLLRRAVLRAANRFPPLKQ 381


                 ..
gi 826327431 461 QI 462
Cdd:PRK09126 382 AI 383
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 48-459 7.12e-41

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 148.93  E-value: 7.12e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  48 AAMACAL---GHDIHfcdkkillleagpkkVLEKLSETYSN-RVSSISPGSATLLSSFGAWDHICnMRYRAFRRMQVWDA 123
Cdd:COG0654   16 LALALALaraGIRVT---------------VVERAPPPRPDgRGIALSPRSLELLRRLGLWDRLL-ARGAPIRGIRVRDG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 124 CS-EALIMFD-KDNLDDMGYIVENDVIMHALTKQLEAvsDRVTVLYRSRAVGYTWpcpftmkDSSPwVHITLGDGSTLQT 201
Cdd:COG0654   80 SDgRVLARFDaAETGLPAGLVVPRADLERALLEAARA--LGVELRFGTEVTGLEQ-------DADG-VTVTLADGRTLRA 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 202 KLLIGADGHNSGVRQAAGIQNVSWNYDQSAVVATLHlseatennVAWQRFLpsgpiallplsdtlsslvwstshehaael 281
Cdd:COG0654  150 DLVVGADGARSAVRRLLGIGFTGRDYPQRALWAGVR--------TELRARL----------------------------- 192

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 282 vsmdeekfvdainsafwndanhtdfidsagtmlqyaisllkptkvsaRQLPPSVASV-EAKSRVLFPLGLGHAAEYVRPR 360
Cdd:COG0654  193 -----------------------------------------------AAAGPRLGELlELSPRSAFPLRRRRAERWRRGR 225

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 361 VALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLStAAFNGRDLGSMnhLTGYETDRQRHNTALLAATDLLKRLYSTNATP 440
Cdd:COG0654  226 VVLLGDAAHTMHPLGGQGANLALRDAAALAWKLA-AALRGRDDEAA--LARYERERRPRAARVQRAADALGRLFHPDSPP 302

                        410
                 ....*....|....*....
gi 826327431 441 LVLLRTWGLQATNAVSPLK 459
Cdd:COG0654  303 LRLLRNAGLRLLDRLPPLK 321
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
85-463 1.10e-39

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 146.97  E-value: 1.10e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  85 NRVSSISPGSATLLSSFGAWDHiCNMRYRAFRRMQVWDACSEAL----IMFDKD--NLDDMGYIVENDVIMHALTKQLEA 158
Cdd:PRK07494  45 LRTTALLGPSIRFLERLGLWAR-LAPHAAPLQSMRIVDATGRLIrapeVRFRAAeiGEDAFGYNIPNWLLNRALEARVAE 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 159 VS--DRVTVLYRSravgytwpcpFTMKDSSpwVHITLGDGSTLQTKLLIGADGHNSGVRQAAGIQNVSWNYDQSAVV-AT 235
Cdd:PRK07494 124 LPniTRFGDEAES----------VRPREDE--VTVTLADGTTLSARLVVGADGRNSPVREAAGIGVRTWSYPQKALVlNF 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 236 LHlsEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAINsafwndanhtdfidsagTMLQ 315
Cdd:PRK07494 192 TH--SRPHQNVSTEFHTEGGPFTQVPLPGRRSSLVWVVRPAEAERLLALSDAALSAAIE-----------------ERMQ 252

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 316 yaiSLLKPTKVSARqlppsvasveaksRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLVhhlST 395
Cdd:PRK07494 253 ---SMLGKLTLEPG-------------RQAWPLSGQVAHRFAAGRTALVGEAAHVFPPIGAQGLNLGLRDVATLV---EI 313

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 396 AAFNGRDLGSMNHLTGYetDRQRHNTALL--AATDLLKRLYSTNATPLVLLRTWGLQATNAVSPLKEQIM 463
Cdd:PRK07494 314 VEDRPEDPGSAAVLAAY--DRARRPDILSrtASVDLLNRSLLSDFLPVQDLRAAGLHLLYSFGPLRRLFM 381
PRK06996 PRK06996
UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;
86-462 2.69e-34

UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;


Pssm-ID: 235905 [Multi-domain]  Cd Length: 398  Bit Score: 132.50  E-value: 2.69e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  86 RVSSISPGSATLLSSFGAWDhicnMRYRAFRRMQVwdacSE------ALIMFDKDNLDDMGYIVENDVIMHALTKQLEAV 159
Cdd:PRK06996  57 RAIALSHGSRVLLETLGAWP----ADATPIEHIHV----SQrghfgrTLIDRDDHDVPALGYVVRYGSLVAALARAVRGT 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 160 sdRVTVLYRSRAVGytwpcPFTMKDSSPWVHITLGDGSTLQTKLLIGADGH-NSGVRQAAGIQNVSWNYDQSAVVATLHL 238
Cdd:PRK06996 129 --PVRWLTSTTAHA-----PAQDADGVTLALGTPQGARTLRARIAVQAEGGlFHDQKADAGDSARRRDYGQTAIVGTVTV 201

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 239 SeATENNVAWQRFLPSGPIALLPLSDTLS---SLVWSTSHEHAAELVSMDEEKFVDAINSAFwndanhtdfidsaGT-ML 314
Cdd:PRK06996 202 S-APRPGWAWERFTHEGPLALLPLGGPRQadyALVWCCAPDEAARRAALPDDAFLAELGAAF-------------GTrMG 267

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 315 QYaisllkptkvsarqlppsvasVEAKSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLS 394
Cdd:PRK06996 268 RF---------------------TRIAGRHAFPLGLNAARTLVNGRIAAVGNAAQTLHPVAGQGLNLGLRDAHTLADALS 326

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 826327431 395 TAAFNGRDLGSMNHltgyetdRQRHNTALLA-ATDLLKRLYSTNATPLVLLRTWGLQATNAVSPLKEQI 462
Cdd:PRK06996 327 DHGATPLALATFAA-------RRALDRRVTIgATDLLPRLFTVDSRPLAHLRGAALTALEFVPPLKHAL 388
PRK06617 PRK06617
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 86-466 4.54e-28

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 168629 [Multi-domain]  Cd Length: 374  Bit Score: 114.64  E-value: 4.54e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  86 RVSSISPGSATLLSSFGAWDHIcnmrYRAFRRMQ-VWDACSEALIMFDKDNLDD--MGYIVENdvimhaltkqleavSDR 162
Cdd:PRK06617  45 RTTALTPHSKNFLFSIDIWEEL----EKFVAEMQdIYVVDNKASEILDLRNDADavLGYVVKN--------------SDF 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 163 VTVLYrSRAVGYTWpcpFTMKDSSPW--------VHITLGDGSTLQTKLLIGADGHNSGVRQAAGIQNVSWNYDQSAVVA 234
Cdd:PRK06617 107 KKILL-SKITNNPL---ITLIDNNQYqevishndYSIIKFDDKQIKCNLLIICDGANSKVRSHYFANEIEKPYQTALTFN 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 235 TLHlsEATENNVAWQRFLPSGPIALLPLSDTL-SSLVWSTSHEHAAELVSM--DEEKFVDAINsafwndanhtdfidsAG 311
Cdd:PRK06617 183 IKH--EKPHENCAMEHFLPLGPFALLPLKDQYaSSVIWSTSSDQAALIVNLpvEEVRFLTQRN---------------AG 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 312 TmlqyaiSLLKPTKVSarqlppsvasvEAKSrvlFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLVH 391
Cdd:PRK06617 246 N------SLGKITIDS-----------EISS---FPLKARIANRYFHNRIVLIADTAHTVHPLAGQGLNQGIKDIEILSM 305

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 826327431 392 HLSTaafNGRdlgsmnhLTGYETDRQRHNTALLAATDLLKRLYSTNATPLVLLRTWGLQATNAVSPLKEQIMAFA 466
Cdd:PRK06617 306 IVSN---NGT-------LQEYQKLRQEDNFIMYKLTDELNNIFSNYSKNLRCLRQIGFKVINNFKPIKNLITSYA 370
PRK06834 PRK06834
hypothetical protein; Provisional
 166-385 3.51e-11

hypothetical protein; Provisional


Pssm-ID: 235870 [Multi-domain]  Cd Length: 488  Bit Score: 65.04  E-value: 3.51e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 166 LYRSRAVgytwpCPFTMKDSSpwVHITLGDGSTLQTKLLIGADGHNSGVRQAAGIQNVSWNYDQSAVVATLHLSEATENN 245
Cdd:PRK06834 117 IYRGREV-----TGFAQDDTG--VDVELSDGRTLRAQYLVGCDGGRSLVRKAAGIDFPGWDPTTSYLIAEVEMTEEPEWG 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 246 V--------AWQRFLPSGPIAllplsdtlssLVWSTSHEHAAELVSMDEEKfvDAINSAFWNDanhtdfidsagtmlqYA 317
Cdd:PRK06834 190 VhrdalgihAFGRLEDEGPVR----------VMVTEKQVGATGEPTLDDLR--EALIAVYGTD---------------YG 242

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 826327431 318 ISllKPTKVS-----ARQlppsvasveaksrvlfplglghAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGD 385
Cdd:PRK06834 243 IH--SPTWISrftdmARQ----------------------AASYRDGRVLLAGDAAHVHSPVGGQGLNTGVQD 291
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 194-427 7.42e-09

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 57.34  E-value: 7.42e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  194 GDGSTLQTKLLIGADGHNSGVRQAAGIQNVSWNYDQSAVVATLHLS------EATENNVAWQRFLPSGPIALLPLSDTLS 267
Cdd:pfam01494 143 GEEYTVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLFDApdlsdpVERAFVHYLIYAPHSRGFMVGPWRSAGR 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  268 S---LVWSTSHEHAAELVSMDEEKFVDAINSAFwndanHTDFIDsagtmlqyaislLKPTKVSArqlppsvasVEAKSRV 344
Cdd:pfam01494 223 EryyVQVPWDEEVEERPEEFTDEELKQRLRSIV-----GIDLAL------------VEILWKSI---------WGVASRV 276

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  345 lfplglghAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLStAAFNGRdlGSMNHLTGYETDRQRHNTALL 424
Cdd:pfam01494 277 --------ATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLAWKLA-AVLRGQ--AGESLLDTYSAERLPVAWAVV 345


                  ...
gi 826327431  425 AAT 427
Cdd:pfam01494 346 DFA 348
PRK07045 PRK07045
putative monooxygenase; Reviewed
 191-425 1.57e-07

putative monooxygenase; Reviewed


Pssm-ID: 136171 [Multi-domain]  Cd Length: 388  Bit Score: 53.37  E-value: 1.57e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 191 ITLGDGSTLQTKLLIGADGHNSGVRQ-AAGIQNVSWNYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPLSDTLSSL 269
Cdd:PRK07045 144 VTLSDGERVAPTVLVGADGARSMIRDdVLRMPAERVPYATPMAFGTIALTDSVRECNRLYVDSNQGLAYFYPIGDQATRL 223

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 270 VWSTSHEHAAELVSmdeekfvdainsafwndanhtdfiDSAGTMLQYAISllkptKVSARQLPPSVASVEAKSRV-LFPL 348
Cdd:PRK07045 224 VVSFPADEMQGYLA------------------------DTTRTKLLARLN-----EFVGDESADAMAAIGAGTAFpLIPL 274

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 826327431 349 GLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLSTaAFNGRdLGSMNHLTGYETDRQRHNTALLA 425
Cdd:PRK07045 275 GRMNLDRYHKRNVVLLGDAAHSIHPITGQGMNLAIEDAGELGACLDL-HLSGQ-IALADALERFERIRRPVNEAVIS 349
PRK08244 PRK08244
monooxygenase;
197-434 2.77e-07

monooxygenase;


Pssm-ID: 236199 [Multi-domain]  Cd Length: 493  Bit Score: 52.82  E-value: 2.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 197 STLQTKLLIGADGHNSGVRQAAGIQNVSWNYDQSAVVATLHLSEATENNVAwQRFLPSGPIALLPLSDTLSSLVWSTSHE 276
Cdd:PRK08244 144 RTLTSSYVVGADGAGSIVRKQAGIAFPGTDATFTAMLGDVVLKDPPPSSVL-SLCTREGGVMIVPLSGGIYRVLIIDPER 222

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 277 HAA---ELVSMDEEKfvdainsafwndanhTDFIDSAGTMLqyaisllkptkvsarqlppSVASVEAKSRvlFPLGLGHA 353
Cdd:PRK08244 223 PQVpkdEPVTLEELK---------------TSLIRICGTDF-------------------GLNDPVWMSR--FGNATRQA 266

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 354 AEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLStAAFNGRDLGSMnhLTGYETDRQRHNTALLAATDLLKRL 433
Cdd:PRK08244 267 ERYRSGRIFLAGDAAHIHFPAGGQGLNVGLQDAMNLGWKLA-AAIKGWAPDWL--LDSYHAERHPVGTALLRNTEVQTKL 343


                 .
gi 826327431 434 Y 434
Cdd:PRK08244 344 F 344
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
75-220 8.11e-06

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 47.27  E-value: 8.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431  75 VLEKLSE-TYSNRVSSISPGSATLLSSFGAWDHICnmryRAFRRMQVWdACSEALIMFDKDNldDMGYIVENDVIMHALT 153
Cdd:COG0644   21 LLEKGSFpGDKICGGGLLPRALEELEPLGLDEPLE----RPVRGARFY-SPGGKSVELPPGR--GGGYVVDRARFDRWLA 93

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 826327431 154 KQleAVSDRVTVLYRSRAVGytwpcpFTMKDSSPWVhiTLGDGSTLQTKLLIGADGHNSGVRQAAGI 220
Cdd:COG0644   94 EQ--AEEAGAEVRTGTRVTD------VLRDDGRVVV--RTGDGEEIRADYVVDADGARSLLARKLGL 150
PRK07236 PRK07236
hypothetical protein; Provisional
 189-425 1.94e-04

hypothetical protein; Provisional


Pssm-ID: 235980 [Multi-domain]  Cd Length: 386  Bit Score: 43.37  E-value: 1.94e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 189 VHITLGDGSTLQTKLLIGADGHNSGVRQA---------AGIqnVSWNydqsAVVATLHLSEATennvaWQRFLPSGPIAL 259
Cdd:PRK07236 131 VTARFADGRRETADLLVGADGGRSTVRAQllpdvrptyAGY--VAWR----GLVDEAALPPEA-----RAALRDRFTFQL 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 260 LPLSDTLSSLVwstshehAAELVSMDEEK----FVdainsAFWNDANHTD----FIDSAGTMLQYAIS--LLKPTKVS-- 327
Cdd:PRK07236 200 GPGSHILGYPV-------PGEDGSTEPGKrrynWV-----WYRNAPAGEEldelLTDRDGTRRPFSVPpgALRDDVLAel 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 328 ----ARQLPPSVAS-VEAKSRVLFPLGLGHAAE-YVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLSTAAfngR 401
Cdd:PRK07236 268 rddaAELLAPVFAElVEATAQPFVQAIFDLEVPrMAFGRVALLGDAAFVARPHTAAGVAKAAADAVALAEALAAAA---G 344

                        250       260
                 ....*....|....*....|....
gi 826327431 402 DLGSMnhLTGYETDRQRHNTALLA 425
Cdd:PRK07236 345 DIDAA--LAAWEAERLAVGAAIVA 366
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
353-447 1.00e-03

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 41.43  E-value: 1.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 826327431 353 AAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLVHHLStAAFNGR---DLgsmnhLTGYETDRQRHNTALLAATDL 429
Cdd:PRK06183 280 ADRWRSGRVLLAGDAAHLMPPFAGQGMNSGIRDAANLAWKLA-AVLRGRagdAL-----LDTYEQERRPHARAMIDLAVR 353

                         90
                 ....*....|....*...
gi 826327431 430 LKRLYSTNATPLVLLRTW 447
Cdd:PRK06183 354 LGRVICPTDRLAAALRDA 371
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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