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Conserved domains on  [gi|795023235|ref|XP_011860871|]
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PREDICTED: mediator of RNA polymerase II transcription subunit 23 [Vollenhovia emeryi]

Protein Classification

Med23 domain-containing protein( domain architecture ID 10569018)

Med23 domain-containing protein

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Med23 pfam11573
Mediator complex subunit 23; Med23 is one of the subunits of the Tail portion of the Mediator ...
 4-1321 0e+00

Mediator complex subunit 23; Med23 is one of the subunits of the Tail portion of the Mediator complex that regulates RNA polymerase II activity. Med23 is required for heat-shock-specific gene expression, and has been shown to mediate transcriptional activation of E1A in mice.


:

Pssm-ID: 463299  Cd Length: 1301  Bit Score: 2306.94  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235     4 EAQITSILNDILKVEAIEEAFSCVLVHHPKKESEKVTAWHQELKTAVTGLTKEQQEAAVRQFLTMAAAMTNHRRLQLLLS 83
Cdd:pfam11573    2 VNQVKSIINEILKVEIIEEAFSGFTSNLPDDEKEKTAILRKQFNNMMSKMSEEEKESLVKELIKLVHHVAEKNRLDFLFQ 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235    84 LLENLVYSNYLPARLVCECILSCDKLQYCLEDFWVECFVLIRHIIGGVDYKGVREIMKGCKEKAQTIPARLDASVQPQLK 163
Cdd:pfam11573   82 LLEYAVQKGIISARLVCEGLIMSEKLVLCNRLFWQECFKLIRKIIPGVDYKGVREILKYCLEKARRLPYSLSPEKVPQLR 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   164 ALENVIEYIFDRNACLLPGYFIVNEIQKAYPDGKNWPHWKLAKLLSNFVESFRNTAQMVSIVGHSKMLPVVEHTGYADYL 243
Cdd:pfam11573  162 ALENVILYILDRNACLLPAYFIVNEIMKGYPDAKMWPHWRLAELLSNFVESFRPIAQMVSIIGRSFMLPVVEHSGYADHL 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   244 INPWLLDPTTLKFSLKGNLPYDPDLLKPQTELLRYVLEQPYSRDMVCSMLGLQKQHKQRCIVLEEQLVELVILAMERSEN 323
Cdd:pfam11573  242 TSPWKLDPATLKFQLKGNLPYRPELLEPQTYLLRYVLEQPYSRDMVCSMLGLQKQHKQRCKALEEQLVELMICAMERSET 321

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   324 ESlpaegmDGTVANHWVWLHLSSQLIYFILFQFACFPSIVMAIHDKLAGRELRKGRDHLMWVLLQFISGSIQRNPLSNFL 403
Cdd:pfam11573  322 EP------EDEPITHWLWLHLSSQLIYFVLFQFASFPNIVKSLHEKLAGRDLTRGRDHLMWVLLQFISGSIQKNPLSDFL 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   404 PVLKLYDLLYPEKEPLPVPDYTQALCTHQMAITCIWIHLLKKAQTEPcTNIHRPIPHTLKVHHEFLQHLVMPNAS--LCM 481
Cdd:pfam11573  396 PILKLYDLLYPEKEPLPVPDYNKPLCTHQMAATCIWIHLLKKAQDEN-QKLQRPIPDTLKSHHEFLQHLVLNNDSpnLAM 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   482 GSDYRIALLCNAYSTNQEYFSRPMAALVDTILGtqknqqqqpMQNLQNNAALANGPTTPLSMSILDSLTVHSKMSLIHSI 561
Cdd:pfam11573  475 GSDYRIALLCNAYSTNTEYFSRPMPALVETILG---------NSKSRSPGCNAPGPTTPLSMEFLDSLTVHSKMSLIHSI 545

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   562 VTHVIKLAQSKSNMALAPALVETYSRLLVYTEIESLGIKGFISQLLPTVFKSHAWGTLYTLLEMFSYRMHHIQPHYRVQL 641
Cdd:pfam11573  546 VTHVIKFAQSKSSVALAPALVETYSRLLVYTEIESLGIKGFISQLLPTVFKSQAWGILHTLLEMFSYRMHHIQPHYRVQL 625

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   642 LSHLHSLAAVPQTNQTQLHLCVESTALRLITGLGSAEVQPQLSRFLSEPKT-LVSAESEELNRALVLTLARSMHVTGTGA 720
Cdd:pfam11573  626 LSHLHSLANVPQTNQTQLHLCVESTALRLITGLGSSEVQPQLSRFLNEPKTfLVSQESEELNRALILTLARAIHITGTGT 705

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   721 DslSGTWCKELLNTIMQNTPHSWANHTLQCFPPVLSEFFQQNSVAKENKQQIKKAVEEEYRNWASMNNENDIIAHFSVPG 800
Cdd:pfam11573  706 D--SESWCKELLETIMQNTPHGWPQHTLSCFPPWLLEFFKQNNVPKENKQQLKKNVEEEYRKWTSMTNENDIIAHFSVPG 783

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   801 TPPLFLCLLWKMILETDRISPIAYKILERIGARALSAHLRKFCDYLVFEFANSVGGQHVNKCVDTINDMIWKYNIVTIDR 880
Cdd:pfam11573  784 TPPLFLCLLWKMLLETDRITPIAYKVLERIGARALSAHLRKFCDYLVFEFTNSCGGQHVNKCADALNDMIWKYNIVTIDR 863

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   881 LVLCLALRTQEGNEAQVCFFIIQLLLLKAAEFRNRVQEFVKENSPEHWKQSNWHEKHLAFHRKFPEKFAPEGIMEQTSgg 960
Cdd:pfam11573  864 LVLCLALRPQEGNEAQVCFFIIQLLLLKTTEFRNRVQDFVKENSPEHWKQPNWHEKHLAYHRKFPEKFAPEGVAEYDS-- 941

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   961 pSQYQNLPVYFGNVCLRFLPVFDIVVHRYLEIPPVIKSLEILLEHLGCLYKFHDRPVTYLYNTLHYYEKKLRDRPLLKRR 1040
Cdd:pfam11573  942 -SSNPYLPTYFGNVCLRFLPVLDIVIHRALELPPVSKSLETLLEHLGCLYKFHDRPVTYLYNTLHYYEHKLRDRPDLKRK 1020

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235  1041 LVSAVLGSLREIRAPGWALSEAYQMYMTRFNDDAVSWVPElDYYIRLVQRIVETMSGTA--HFPATDWRFNEFPNPAAHA 1118
Cdd:pfam11573 1021 LVSAIIGSLKDCRPPGWALTEAYEKYHQKSSDEQLIWLPE-DYYMKLIDRMVDTMDGKTppPFPAKDWRFNEFPNPGAHA 1099

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235  1119 LYVTCVELMALPVAPDAVANFLLDVVAKGYTVVPSDEIHLWINCVGLLLAALPECYWSALHKRLLETISSPGLVNWQYNN 1198
Cdd:pfam11573 1100 LYVTCVELMALPVSPETVANALIDVVQKGYHLIPRNQIHLWINAIGLILTALPESYWSVLHDRIVEVLSNPELTNWTYPC 1179

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235  1199 lTPFQMFNFNITHNSLLENKYSYMLALAHSVWHHAGVGQITTMPQFIKEKLQPVVSSEEQLIYACHLIGPTLARFNAERP 1278
Cdd:pfam11573 1180 -SPFELFNFDNYHESLLENRASYILALAHAVWHHAGIGQLNPFPQFVKEKLLPHVKTEEQLLYLCHLVGPFLQRFRAERE 1258

                         1290      1300      1310      1320
                   ....*....|....*....|....*....|....*....|...
gi 795023235  1279 HCVVELAVCLYEMLERVDHTQTTLSYMDPICDLLYHIKYMFVG 1321
Cdd:pfam11573 1259 RGVLDITKLLYELLEQVDKEGVELRYMDPICDLLYHIKYMFVG 1301
 
Name Accession Description Interval E-value
Med23 pfam11573
Mediator complex subunit 23; Med23 is one of the subunits of the Tail portion of the Mediator ...
 4-1321 0e+00

Mediator complex subunit 23; Med23 is one of the subunits of the Tail portion of the Mediator complex that regulates RNA polymerase II activity. Med23 is required for heat-shock-specific gene expression, and has been shown to mediate transcriptional activation of E1A in mice.


Pssm-ID: 463299  Cd Length: 1301  Bit Score: 2306.94  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235     4 EAQITSILNDILKVEAIEEAFSCVLVHHPKKESEKVTAWHQELKTAVTGLTKEQQEAAVRQFLTMAAAMTNHRRLQLLLS 83
Cdd:pfam11573    2 VNQVKSIINEILKVEIIEEAFSGFTSNLPDDEKEKTAILRKQFNNMMSKMSEEEKESLVKELIKLVHHVAEKNRLDFLFQ 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235    84 LLENLVYSNYLPARLVCECILSCDKLQYCLEDFWVECFVLIRHIIGGVDYKGVREIMKGCKEKAQTIPARLDASVQPQLK 163
Cdd:pfam11573   82 LLEYAVQKGIISARLVCEGLIMSEKLVLCNRLFWQECFKLIRKIIPGVDYKGVREILKYCLEKARRLPYSLSPEKVPQLR 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   164 ALENVIEYIFDRNACLLPGYFIVNEIQKAYPDGKNWPHWKLAKLLSNFVESFRNTAQMVSIVGHSKMLPVVEHTGYADYL 243
Cdd:pfam11573  162 ALENVILYILDRNACLLPAYFIVNEIMKGYPDAKMWPHWRLAELLSNFVESFRPIAQMVSIIGRSFMLPVVEHSGYADHL 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   244 INPWLLDPTTLKFSLKGNLPYDPDLLKPQTELLRYVLEQPYSRDMVCSMLGLQKQHKQRCIVLEEQLVELVILAMERSEN 323
Cdd:pfam11573  242 TSPWKLDPATLKFQLKGNLPYRPELLEPQTYLLRYVLEQPYSRDMVCSMLGLQKQHKQRCKALEEQLVELMICAMERSET 321

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   324 ESlpaegmDGTVANHWVWLHLSSQLIYFILFQFACFPSIVMAIHDKLAGRELRKGRDHLMWVLLQFISGSIQRNPLSNFL 403
Cdd:pfam11573  322 EP------EDEPITHWLWLHLSSQLIYFVLFQFASFPNIVKSLHEKLAGRDLTRGRDHLMWVLLQFISGSIQKNPLSDFL 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   404 PVLKLYDLLYPEKEPLPVPDYTQALCTHQMAITCIWIHLLKKAQTEPcTNIHRPIPHTLKVHHEFLQHLVMPNAS--LCM 481
Cdd:pfam11573  396 PILKLYDLLYPEKEPLPVPDYNKPLCTHQMAATCIWIHLLKKAQDEN-QKLQRPIPDTLKSHHEFLQHLVLNNDSpnLAM 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   482 GSDYRIALLCNAYSTNQEYFSRPMAALVDTILGtqknqqqqpMQNLQNNAALANGPTTPLSMSILDSLTVHSKMSLIHSI 561
Cdd:pfam11573  475 GSDYRIALLCNAYSTNTEYFSRPMPALVETILG---------NSKSRSPGCNAPGPTTPLSMEFLDSLTVHSKMSLIHSI 545

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   562 VTHVIKLAQSKSNMALAPALVETYSRLLVYTEIESLGIKGFISQLLPTVFKSHAWGTLYTLLEMFSYRMHHIQPHYRVQL 641
Cdd:pfam11573  546 VTHVIKFAQSKSSVALAPALVETYSRLLVYTEIESLGIKGFISQLLPTVFKSQAWGILHTLLEMFSYRMHHIQPHYRVQL 625

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   642 LSHLHSLAAVPQTNQTQLHLCVESTALRLITGLGSAEVQPQLSRFLSEPKT-LVSAESEELNRALVLTLARSMHVTGTGA 720
Cdd:pfam11573  626 LSHLHSLANVPQTNQTQLHLCVESTALRLITGLGSSEVQPQLSRFLNEPKTfLVSQESEELNRALILTLARAIHITGTGT 705

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   721 DslSGTWCKELLNTIMQNTPHSWANHTLQCFPPVLSEFFQQNSVAKENKQQIKKAVEEEYRNWASMNNENDIIAHFSVPG 800
Cdd:pfam11573  706 D--SESWCKELLETIMQNTPHGWPQHTLSCFPPWLLEFFKQNNVPKENKQQLKKNVEEEYRKWTSMTNENDIIAHFSVPG 783

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   801 TPPLFLCLLWKMILETDRISPIAYKILERIGARALSAHLRKFCDYLVFEFANSVGGQHVNKCVDTINDMIWKYNIVTIDR 880
Cdd:pfam11573  784 TPPLFLCLLWKMLLETDRITPIAYKVLERIGARALSAHLRKFCDYLVFEFTNSCGGQHVNKCADALNDMIWKYNIVTIDR 863

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   881 LVLCLALRTQEGNEAQVCFFIIQLLLLKAAEFRNRVQEFVKENSPEHWKQSNWHEKHLAFHRKFPEKFAPEGIMEQTSgg 960
Cdd:pfam11573  864 LVLCLALRPQEGNEAQVCFFIIQLLLLKTTEFRNRVQDFVKENSPEHWKQPNWHEKHLAYHRKFPEKFAPEGVAEYDS-- 941

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   961 pSQYQNLPVYFGNVCLRFLPVFDIVVHRYLEIPPVIKSLEILLEHLGCLYKFHDRPVTYLYNTLHYYEKKLRDRPLLKRR 1040
Cdd:pfam11573  942 -SSNPYLPTYFGNVCLRFLPVLDIVIHRALELPPVSKSLETLLEHLGCLYKFHDRPVTYLYNTLHYYEHKLRDRPDLKRK 1020

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235  1041 LVSAVLGSLREIRAPGWALSEAYQMYMTRFNDDAVSWVPElDYYIRLVQRIVETMSGTA--HFPATDWRFNEFPNPAAHA 1118
Cdd:pfam11573 1021 LVSAIIGSLKDCRPPGWALTEAYEKYHQKSSDEQLIWLPE-DYYMKLIDRMVDTMDGKTppPFPAKDWRFNEFPNPGAHA 1099

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235  1119 LYVTCVELMALPVAPDAVANFLLDVVAKGYTVVPSDEIHLWINCVGLLLAALPECYWSALHKRLLETISSPGLVNWQYNN 1198
Cdd:pfam11573 1100 LYVTCVELMALPVSPETVANALIDVVQKGYHLIPRNQIHLWINAIGLILTALPESYWSVLHDRIVEVLSNPELTNWTYPC 1179

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235  1199 lTPFQMFNFNITHNSLLENKYSYMLALAHSVWHHAGVGQITTMPQFIKEKLQPVVSSEEQLIYACHLIGPTLARFNAERP 1278
Cdd:pfam11573 1180 -SPFELFNFDNYHESLLENRASYILALAHAVWHHAGIGQLNPFPQFVKEKLLPHVKTEEQLLYLCHLVGPFLQRFRAERE 1258

                         1290      1300      1310      1320
                   ....*....|....*....|....*....|....*....|...
gi 795023235  1279 HCVVELAVCLYEMLERVDHTQTTLSYMDPICDLLYHIKYMFVG 1321
Cdd:pfam11573 1259 RGVLDITKLLYELLEQVDKEGVELRYMDPICDLLYHIKYMFVG 1301
 
Name Accession Description Interval E-value
Med23 pfam11573
Mediator complex subunit 23; Med23 is one of the subunits of the Tail portion of the Mediator ...
 4-1321 0e+00

Mediator complex subunit 23; Med23 is one of the subunits of the Tail portion of the Mediator complex that regulates RNA polymerase II activity. Med23 is required for heat-shock-specific gene expression, and has been shown to mediate transcriptional activation of E1A in mice.


Pssm-ID: 463299  Cd Length: 1301  Bit Score: 2306.94  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235     4 EAQITSILNDILKVEAIEEAFSCVLVHHPKKESEKVTAWHQELKTAVTGLTKEQQEAAVRQFLTMAAAMTNHRRLQLLLS 83
Cdd:pfam11573    2 VNQVKSIINEILKVEIIEEAFSGFTSNLPDDEKEKTAILRKQFNNMMSKMSEEEKESLVKELIKLVHHVAEKNRLDFLFQ 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235    84 LLENLVYSNYLPARLVCECILSCDKLQYCLEDFWVECFVLIRHIIGGVDYKGVREIMKGCKEKAQTIPARLDASVQPQLK 163
Cdd:pfam11573   82 LLEYAVQKGIISARLVCEGLIMSEKLVLCNRLFWQECFKLIRKIIPGVDYKGVREILKYCLEKARRLPYSLSPEKVPQLR 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   164 ALENVIEYIFDRNACLLPGYFIVNEIQKAYPDGKNWPHWKLAKLLSNFVESFRNTAQMVSIVGHSKMLPVVEHTGYADYL 243
Cdd:pfam11573  162 ALENVILYILDRNACLLPAYFIVNEIMKGYPDAKMWPHWRLAELLSNFVESFRPIAQMVSIIGRSFMLPVVEHSGYADHL 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   244 INPWLLDPTTLKFSLKGNLPYDPDLLKPQTELLRYVLEQPYSRDMVCSMLGLQKQHKQRCIVLEEQLVELVILAMERSEN 323
Cdd:pfam11573  242 TSPWKLDPATLKFQLKGNLPYRPELLEPQTYLLRYVLEQPYSRDMVCSMLGLQKQHKQRCKALEEQLVELMICAMERSET 321

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   324 ESlpaegmDGTVANHWVWLHLSSQLIYFILFQFACFPSIVMAIHDKLAGRELRKGRDHLMWVLLQFISGSIQRNPLSNFL 403
Cdd:pfam11573  322 EP------EDEPITHWLWLHLSSQLIYFVLFQFASFPNIVKSLHEKLAGRDLTRGRDHLMWVLLQFISGSIQKNPLSDFL 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   404 PVLKLYDLLYPEKEPLPVPDYTQALCTHQMAITCIWIHLLKKAQTEPcTNIHRPIPHTLKVHHEFLQHLVMPNAS--LCM 481
Cdd:pfam11573  396 PILKLYDLLYPEKEPLPVPDYNKPLCTHQMAATCIWIHLLKKAQDEN-QKLQRPIPDTLKSHHEFLQHLVLNNDSpnLAM 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   482 GSDYRIALLCNAYSTNQEYFSRPMAALVDTILGtqknqqqqpMQNLQNNAALANGPTTPLSMSILDSLTVHSKMSLIHSI 561
Cdd:pfam11573  475 GSDYRIALLCNAYSTNTEYFSRPMPALVETILG---------NSKSRSPGCNAPGPTTPLSMEFLDSLTVHSKMSLIHSI 545

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   562 VTHVIKLAQSKSNMALAPALVETYSRLLVYTEIESLGIKGFISQLLPTVFKSHAWGTLYTLLEMFSYRMHHIQPHYRVQL 641
Cdd:pfam11573  546 VTHVIKFAQSKSSVALAPALVETYSRLLVYTEIESLGIKGFISQLLPTVFKSQAWGILHTLLEMFSYRMHHIQPHYRVQL 625

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   642 LSHLHSLAAVPQTNQTQLHLCVESTALRLITGLGSAEVQPQLSRFLSEPKT-LVSAESEELNRALVLTLARSMHVTGTGA 720
Cdd:pfam11573  626 LSHLHSLANVPQTNQTQLHLCVESTALRLITGLGSSEVQPQLSRFLNEPKTfLVSQESEELNRALILTLARAIHITGTGT 705

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   721 DslSGTWCKELLNTIMQNTPHSWANHTLQCFPPVLSEFFQQNSVAKENKQQIKKAVEEEYRNWASMNNENDIIAHFSVPG 800
Cdd:pfam11573  706 D--SESWCKELLETIMQNTPHGWPQHTLSCFPPWLLEFFKQNNVPKENKQQLKKNVEEEYRKWTSMTNENDIIAHFSVPG 783

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   801 TPPLFLCLLWKMILETDRISPIAYKILERIGARALSAHLRKFCDYLVFEFANSVGGQHVNKCVDTINDMIWKYNIVTIDR 880
Cdd:pfam11573  784 TPPLFLCLLWKMLLETDRITPIAYKVLERIGARALSAHLRKFCDYLVFEFTNSCGGQHVNKCADALNDMIWKYNIVTIDR 863

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   881 LVLCLALRTQEGNEAQVCFFIIQLLLLKAAEFRNRVQEFVKENSPEHWKQSNWHEKHLAFHRKFPEKFAPEGIMEQTSgg 960
Cdd:pfam11573  864 LVLCLALRPQEGNEAQVCFFIIQLLLLKTTEFRNRVQDFVKENSPEHWKQPNWHEKHLAYHRKFPEKFAPEGVAEYDS-- 941

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235   961 pSQYQNLPVYFGNVCLRFLPVFDIVVHRYLEIPPVIKSLEILLEHLGCLYKFHDRPVTYLYNTLHYYEKKLRDRPLLKRR 1040
Cdd:pfam11573  942 -SSNPYLPTYFGNVCLRFLPVLDIVIHRALELPPVSKSLETLLEHLGCLYKFHDRPVTYLYNTLHYYEHKLRDRPDLKRK 1020

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235  1041 LVSAVLGSLREIRAPGWALSEAYQMYMTRFNDDAVSWVPElDYYIRLVQRIVETMSGTA--HFPATDWRFNEFPNPAAHA 1118
Cdd:pfam11573 1021 LVSAIIGSLKDCRPPGWALTEAYEKYHQKSSDEQLIWLPE-DYYMKLIDRMVDTMDGKTppPFPAKDWRFNEFPNPGAHA 1099

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235  1119 LYVTCVELMALPVAPDAVANFLLDVVAKGYTVVPSDEIHLWINCVGLLLAALPECYWSALHKRLLETISSPGLVNWQYNN 1198
Cdd:pfam11573 1100 LYVTCVELMALPVSPETVANALIDVVQKGYHLIPRNQIHLWINAIGLILTALPESYWSVLHDRIVEVLSNPELTNWTYPC 1179

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 795023235  1199 lTPFQMFNFNITHNSLLENKYSYMLALAHSVWHHAGVGQITTMPQFIKEKLQPVVSSEEQLIYACHLIGPTLARFNAERP 1278
Cdd:pfam11573 1180 -SPFELFNFDNYHESLLENRASYILALAHAVWHHAGIGQLNPFPQFVKEKLLPHVKTEEQLLYLCHLVGPFLQRFRAERE 1258

                         1290      1300      1310      1320
                   ....*....|....*....|....*....|....*....|...
gi 795023235  1279 HCVVELAVCLYEMLERVDHTQTTLSYMDPICDLLYHIKYMFVG 1321
Cdd:pfam11573 1259 RGVLDITKLLYELLEQVDKEGVELRYMDPICDLLYHIKYMFVG 1301
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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