|
Name |
Accession |
Description |
Interval |
E-value |
| INCENP_N |
pfam12178 |
Chromosome passenger complex (CPC) protein INCENP N terminal; This domain family is found in ... |
6-41 |
7.94e-17 |
|
Chromosome passenger complex (CPC) protein INCENP N terminal; This domain family is found in eukaryotes, and is approximately 40 amino acids in length. INCENP is a regulatory protein in the chromosome passenger complex. It is involved in regulation of the catalytic protein Aurora B. It performs this function in association with two other proteins - Survivin and Borealin. These proteins form a tight three-helical bundle. The N terminal domain is the domain involved in formation of this three helical bundle.
Pssm-ID: 463484 [Multi-domain] Cd Length: 36 Bit Score: 74.66 E-value: 7.94e-17
10 20 30
....*....|....*....|....*....|....*.
gi 767968088 6 PGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEA 41
Cdd:pfam12178 1 SGPASLLEVCDQKLSEFLCEIDNKHLVWLEEIEEEA 36
|
|
| INCENP_ARK-bind |
pfam03941 |
Inner centromere protein, ARK binding region; This region of the inner centromere protein has ... |
834-888 |
3.51e-15 |
|
Inner centromere protein, ARK binding region; This region of the inner centromere protein has been found to be necessary and sufficient for binding to aurora-related kinase. This interaction has been implicated in the coordination of chromosome segregation with cell division in yeast.
Pssm-ID: 461100 [Multi-domain] Cd Length: 53 Bit Score: 70.30 E-value: 3.51e-15
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 767968088 834 NSDDSTDDEAHPRKPIPTWARGTPLSQAIIHQYyhPPNLLELFGTILPLDLEDIF 888
Cdd:pfam03941 1 NSDDEDDDEDEPRKPVPSWAQSPNLRQALIRQE--PIDPDEIFGPIPPLNLEEIF 53
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
531-786 |
1.96e-11 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 68.24 E-value: 1.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKR-----RRLEEVK----LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQ 601
Cdd:PTZ00121 1505 AAEAKKKADEAKKAEEAKKADEAKKAEEAKkadeaKKAEEKKkadeLKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAE 1584
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 602 IDEKTEKAK-EERLAEEKAKKKAAAKKMEEVEARR------KQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKA 674
Cdd:PTZ00121 1585 EAKKAEEARiEEVMKLYEEEKKMKAEEAKKAEEAKikaeelKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAA 1664
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 675 AEAKRlAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAErELQEREKALRLQKEQLQRELEEK 754
Cdd:PTZ00121 1665 EEAKK-AEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAE-ELKKAEEENKIKAEEAKKEAEED 1742
|
250 260 270
....*....|....*....|....*....|....*...
gi 767968088 755 KKKEEQQRLAE------RQLQEEQEKKAKEAAGASKAL 786
Cdd:PTZ00121 1743 KKKAEEAKKDEeekkkiAHLKKEEEKKAEEIRKEKEAV 1780
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
531-780 |
2.79e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 67.65 E-value: 2.79e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKfaQIDEKTEKAK 610
Cdd:COG1196 244 LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERR--RELEERLEEL 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 611 EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE 690
Cdd:COG1196 322 EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 691 QERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQE 770
Cdd:COG1196 402 LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE 481
|
250
....*....|
gi 767968088 771 EQEKKAKEAA 780
Cdd:COG1196 482 LLEELAEAAA 491
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
531-785 |
3.09e-11 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 67.86 E-value: 3.09e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMK---EEKKKQIEQKFAQIDEKTE 607
Cdd:PTZ00121 1285 KAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKkaaEAAKAEAEAAADEAEAAEE 1364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 608 KAKEERLAEEKAKKKaaakkmeeVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQerlRKAAEAKRLAEQREQE 687
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKK--------ADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK---KKADEAKKKAEEKKKA 1433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 688 RREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK--EQLQRELEEKKKKEEQQRLAE 765
Cdd:PTZ00121 1434 DEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKkaEEAKKKADEAKKAAEAKKKAD 1513
|
250 260
....*....|....*....|
gi 767968088 766 RQLQEEQEKKAKEAAGASKA 785
Cdd:PTZ00121 1514 EAKKAEEAKKADEAKKAEEA 1533
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
531-784 |
8.62e-11 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 66.32 E-value: 8.62e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREErLRKVLQARERVEQMK--EEKKKQIEQKFAQIDEKTEK 608
Cdd:PTZ00121 1570 KKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEE-AKKAEEAKIKAEELKkaEEEKKKVEQLKKKEAEEKKK 1648
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 609 AKEERlaeekakKKAAAKKMEEVEARRKQEEEARRLRwlqqeeeerrhqellQKKKEEEQERlRKAAEAKRLAEQREQER 688
Cdd:PTZ00121 1649 AEELK-------KAEEENKIKAAEEAKKAEEDKKKAE---------------EAKKAEEDEK-KAAEALKKEAEEAKKAE 1705
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 689 REQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQL 768
Cdd:PTZ00121 1706 ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEEL 1785
|
250
....*....|....*.
gi 767968088 769 QEEQEKKAKEAAGASK 784
Cdd:PTZ00121 1786 DEEDEKRRMEVDKKIK 1801
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
531-777 |
3.79e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 64.39 E-value: 3.79e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEE----AEQLRRqKVEEDKRRRlEEVKlKREERLRKVLQARERVEQMK--EEKKKQIEQKfAQIDE 604
Cdd:PTZ00121 1373 KEEAKKKADAAKKKAEekkkADEAKK-KAEEDKKKA-DELK-KAAAAKKKADEAKKKAEEKKkaDEAKKKAEEA-KKADE 1448
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 605 KTEKAKEERlaeEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ---ERLRKAAEAKRLA 681
Cdd:PTZ00121 1449 AKKKAEEAK---KAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKkkaDEAKKAEEAKKAD 1525
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 682 EQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 761
Cdd:PTZ00121 1526 EAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK 1605
|
250
....*....|....*.
gi 767968088 762 RLAERQLQEEQEKKAK 777
Cdd:PTZ00121 1606 KMKAEEAKKAEEAKIK 1621
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
521-679 |
6.80e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 63.24 E-value: 6.80e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 521 KRNTPLRMDPKEKERQRLENLRRKEE----AEQLRRqkvEEDKRRRLEEVKLKREERLRKVLQARERVEQMK----EEKK 592
Cdd:PTZ00121 1592 ARIEEVMKLYEEEKKMKAEEAKKAEEakikAEELKK---AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKikaaEEAK 1668
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 593 KQIEQKfaQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQErlR 672
Cdd:PTZ00121 1669 KAEEDK--KKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDK--K 1744
|
....*..
gi 767968088 673 KAAEAKR 679
Cdd:PTZ00121 1745 KAEEAKK 1751
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
531-785 |
1.22e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 62.47 E-value: 1.22e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRK-EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERveqmKEEKKKQIEQKFAqidEKTEKA 609
Cdd:PTZ00121 1452 KAEEAKKAEEAKKKaEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKA----AEAKKKADEAKKA---EEAKKA 1524
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 610 KEERlaeekakkkaAAKKMEEVEARRKQEE--EARRLRWLQQEEEERRHQELLQKKKEEEQER--LRKAAEAKRLAEQRE 685
Cdd:PTZ00121 1525 DEAK----------KAEEAKKADEAKKAEEkkKADELKKAEELKKAEEKKKAEEAKKAEEDKNmaLRKAEEAKKAEEARI 1594
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 686 QERREQERREQERREQE-RREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ---RELEEKKKKEEQQ 761
Cdd:PTZ00121 1595 EEVMKLYEEEKKMKAEEaKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEEnkiKAAEEAKKAEEDK 1674
|
250 260
....*....|....*....|....
gi 767968088 762 RLAERQLQEEQEKKAKEAAGASKA 785
Cdd:PTZ00121 1675 KKAEEAKKAEEDEKKAAEALKKEA 1698
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
532-786 |
2.24e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 61.49 E-value: 2.24e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 532 EKERQrLENLRRkeEAEQLRR-QKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAK 610
Cdd:COG1196 197 ELERQ-LEPLER--QAEKAERyRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 611 EERLAE------------EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLrKAAEAK 678
Cdd:COG1196 274 LELEELeleleeaqaeeyELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL-EEAEEE 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 679 RLAEQREQERREQERREQERREQERREQERREQERQL-----AEQERRREQERLQAERELQEREKALRLQKEQLQRELEE 753
Cdd:COG1196 353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLealraAAELAAQLEELEEAEEALLERLERLEEELEELEEALAE 432
|
250 260 270
....*....|....*....|....*....|...
gi 767968088 754 KKKKEEQQRLAERQLQEEQEKKAKEAAGASKAL 786
Cdd:COG1196 433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
531-777 |
2.30e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 61.70 E-value: 2.30e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEE-----AEQLRRQKVEEDKRRRLEEVKLKRE-ERLRKVLQARERVEQMK-EEKKKQIEQKFAqid 603
Cdd:PTZ00121 1478 KAEEAKKADEAKKKAEeakkkADEAKKAAEAKKKADEAKKAEEAKKaDEAKKAEEAKKADEAKKaEEKKKADELKKA--- 1554
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 604 EKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ---ERLRKAAEAKRL 680
Cdd:PTZ00121 1555 EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKikaEELKKAEEEKKK 1634
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 681 AEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQ 760
Cdd:PTZ00121 1635 VEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEE 1714
|
250
....*....|....*..
gi 767968088 761 QRLAERQLQEEQEKKAK 777
Cdd:PTZ00121 1715 KKKAEELKKAEEENKIK 1731
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
532-785 |
3.70e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 60.93 E-value: 3.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 532 EKERQRLENLRRKEEAEQLRRQ-KVEEDKRRRLEEVKLKREERlRKVLQARERVEQMK--EEKKKQIEQKfAQIDEKTEK 608
Cdd:PTZ00121 1401 EEDKKKADELKKAAAAKKKADEaKKKAEEKKKADEAKKKAEEA-KKADEAKKKAEEAKkaEEAKKKAEEA-KKADEAKKK 1478
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 609 AKEERlAEEKAKKKAAAKKMEEVEARRKQE-----------EEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEA 677
Cdd:PTZ00121 1479 AEEAK-KADEAKKKAEEAKKKADEAKKAAEakkkadeakkaEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEEL 1557
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 678 KRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE---RELQEREKALRLQKEQLQRELEEK 754
Cdd:PTZ00121 1558 KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEeakKAEEAKIKAEELKKAEEEKKKVEQ 1637
|
250 260 270
....*....|....*....|....*....|...
gi 767968088 755 KKKEEQQ--RLAERQLQEEQEKKAKEAAGASKA 785
Cdd:PTZ00121 1638 LKKKEAEekKKAEELKKAEEENKIKAAEEAKKA 1670
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
531-788 |
2.23e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 58.02 E-value: 2.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKR-RRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKA 609
Cdd:COG1196 267 AELEELRLELEELELELEEAQAEEYELLAElARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 610 KEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRwlqqeeeerRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR 689
Cdd:COG1196 347 EEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE---------ELAEELLEALRAAAELAAQLEELEEAEEALLERLE 417
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 690 EQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 769
Cdd:COG1196 418 RLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLL 497
|
250
....*....|....*....
gi 767968088 770 EEQEKKAKEAAGASKALNV 788
Cdd:COG1196 498 EAEADYEGFLEGVKAALLL 516
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
531-785 |
3.31e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 57.84 E-value: 3.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEE---AEQLRR----QKVEEDKR----RRLEEVK----LKREERLRKVLQARERVEQMKEEKKKQI 595
Cdd:PTZ00121 1171 KAEDAKKAEAARKAEEvrkAEELRKaedaRKAEAARKaeeeRKAEEARkaedAKKAEAVKKAEEAKKDAEEAKKAEEERN 1250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 596 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE-----EARRLRWLQQEEEERRHQELLQKKKEEEQER 670
Cdd:PTZ00121 1251 NEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEakkaeEKKKADEAKKKAEEAKKADEAKKKAEEAKKK 1330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 671 L----RKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAErELQEREKALRLQKEQ 746
Cdd:PTZ00121 1331 AdaakKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD-EAKKKAEEDKKKADE 1409
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 767968088 747 LQRELEEKKKKEEQQRLAERQLQ-EEQEKKAKEAAGASKA 785
Cdd:PTZ00121 1410 LKKAAAAKKKADEAKKKAEEKKKaDEAKKKAEEAKKADEA 1449
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
520-677 |
6.79e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 56.69 E-value: 6.79e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 520 IKRNTPLRMDPKEKERQRLENLRRKEEAEQLRR----QKVEEDKR-----RRLEEVKLKREERLRKVLQARERVEQMKee 590
Cdd:PTZ00121 1631 EKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAaeeaKKAEEDKKkaeeaKKAEEDEKKAAEALKKEAEEAKKAEELK-- 1708
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 591 KKKQIEQKFAqidEKTEKAKEERLAEEKakkkaaakkmeevEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQER 670
Cdd:PTZ00121 1709 KKEAEEKKKA---EELKKAEEENKIKAE-------------EAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEE 1772
|
....*..
gi 767968088 671 LRKAAEA 677
Cdd:PTZ00121 1773 IRKEKEA 1779
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
522-780 |
9.05e-08 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 56.13 E-value: 9.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 522 RNTPLRMDPKEKERQRLENLRRKEEAEQLRR-----QKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIE 596
Cdd:pfam02463 196 KLQELKLKEQAKKALEYYQLKEKLELEEEYLlyldyLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENK 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 597 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAE 676
Cdd:pfam02463 276 EEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEE 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 677 AKRlAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKK 756
Cdd:pfam02463 356 EEE-EELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEE 434
|
250 260
....*....|....*....|....
gi 767968088 757 KEEQQRLAERQLQEEQEKKAKEAA 780
Cdd:pfam02463 435 EEESIELKQGKLTEEKEELEKQEL 458
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
531-785 |
1.21e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 55.92 E-value: 1.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKR-----RRLEEVK----LKREERLRKVLQAR--------ERVEQMKEEKKK 593
Cdd:PTZ00121 1147 KAEDAKRVEIARKAEDARKAEEARKAEDAKkaeaaRKAEEVRkaeeLRKAEDARKAEAARkaeeerkaEEARKAEDAKKA 1226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 594 QIEQKFAQIDEKTE---KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQER 670
Cdd:PTZ00121 1227 EAVKKAEEAKKDAEeakKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADE 1306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 671 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERlqaerelQEREKALRLQKEQLQRE 750
Cdd:PTZ00121 1307 AKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAA-------EEKAEAAEKKKEEAKKK 1379
|
250 260 270
....*....|....*....|....*....|....*..
gi 767968088 751 LEEKKKKEEQQRLAE--RQLQEEQEKKAKEAAGASKA 785
Cdd:PTZ00121 1380 ADAAKKKAEEKKKADeaKKKAEEDKKKADELKKAAAA 1416
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
539-786 |
2.76e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 54.76 E-value: 2.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 539 ENLRRKEEAEQLRRQKVEEDkrRRLEEVKlKREERLRKVLQARERVEQMK-EEKKKQIEQKFAQIDEKTEKAKEERLAEE 617
Cdd:PTZ00121 1095 EAFGKAEEAKKTETGKAEEA--RKAEEAK-KKAEDARKAEEARKAEDARKaEEARKAEDAKRVEIARKAEDARKAEEARK 1171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 618 KAKKKAAAKKMEEVEARRKQE----EEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQER 693
Cdd:PTZ00121 1172 AEDAKKAEAARKAEEVRKAEElrkaEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNN 1251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 694 REQERREQERREQERREQERQLAEQERRREQErlqaeRELQEREKALRLQKEQLQRELEEKKKKEEQQRLAErqlqeEQE 773
Cdd:PTZ00121 1252 EEIRKFEEARMAHFARRQAAIKAEEARKADEL-----KKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAD-----EAK 1321
|
250
....*....|...
gi 767968088 774 KKAKEAAGASKAL 786
Cdd:PTZ00121 1322 KKAEEAKKKADAA 1334
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
527-794 |
7.59e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.02 E-value: 7.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 527 RMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQmKEEKKKQIEQKFAQIDEKT 606
Cdd:COG1196 303 DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE-AEEALLEAEAELAEAEEEL 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 607 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRwlqqEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ 686
Cdd:COG1196 382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLE----EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE 457
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 687 ERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKkeeqqrlAER 766
Cdd:COG1196 458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVA-------VLI 530
|
250 260
....*....|....*....|....*...
gi 767968088 767 QLQEEQEKKAKEAAGASKALNVTVDVQV 794
Cdd:COG1196 531 GVEAAYEAALEAALAAALQNIVVEDDEV 558
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
531-785 |
8.37e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 53.22 E-value: 8.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREER----------LRKVLQARERVEQMKEEKKKQIEQKFA 600
Cdd:PTZ00121 1207 KAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERnneeirkfeeARMAHFARRQAAIKAEEARKADELKKA 1286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 601 QIDEKTEKAK--EERLAEEKAKKKAAAKKMEEvEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE----EQERLRKA 674
Cdd:PTZ00121 1287 EEKKKADEAKkaEEKKKADEAKKKAEEAKKAD-EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEaaadEAEAAEEK 1365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 675 AEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAErELQEREKALRLQKEQLQRELEEK 754
Cdd:PTZ00121 1366 AEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKAD-EAKKKAEEKKKADEAKKKAEEAK 1444
|
250 260 270
....*....|....*....|....*....|.
gi 767968088 755 KKKEEQQRLAERQLQEEQEKKAKEAAGASKA 785
Cdd:PTZ00121 1445 KADEAKKKAEEAKKAEEAKKKAEEAKKADEA 1475
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
531-785 |
5.66e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.52 E-value: 5.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEEAEQL----------RRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFA 600
Cdd:PTZ00121 1238 DAEEAKKAEEERNNEEIRKFeearmahfarRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKA 1317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 601 qidEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRlrwlqQEEEERRHQELLQKKKEEEQerlRKAAEAKRL 680
Cdd:PTZ00121 1318 ---DEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAD-----EAEAAEEKAEAAEKKKEEAK---KKADAAKKK 1386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 681 AEQREQERREQERREQERREQER-REQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQREleekKKKEE 759
Cdd:PTZ00121 1387 AEEKKKADEAKKKAEEDKKKADElKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAK----KAEEA 1462
|
250 260
....*....|....*....|....*.
gi 767968088 760 QQRLAERQLQEEQEKKAKEAAGASKA 785
Cdd:PTZ00121 1463 KKKAEEAKKADEAKKKAEEAKKADEA 1488
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
531-786 |
7.35e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 49.97 E-value: 7.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLEnlrrkEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKqiEQKFAQIDEKTEKAK 610
Cdd:pfam02463 151 KPERRLEIE-----EEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKK--ALEYYQLKEKLELEE 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 611 EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE 690
Cdd:pfam02463 224 EYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELL 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 691 QERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQE 770
Cdd:pfam02463 304 KLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLES 383
|
250
....*....|....*.
gi 767968088 771 EQEKKAKEAAGASKAL 786
Cdd:pfam02463 384 ERLSSAAKLKEEELEL 399
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
531-789 |
8.38e-06 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 49.74 E-value: 8.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEEAEQLRRQK--VEEDKRRRLEEVKLKRE---ERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEK 605
Cdd:pfam17380 346 RERELERIRQEERKRELERIRQEEiaMEISRMRELERLQMERQqknERVRQELEAARKVKILEEERQRKIQQQKVEMEQI 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 606 TEKAKEERlaeekakkkaaakkmeEVEARRKQEEEARRLRWLQQEEEERRHQelLQKKKEEEQERLRKAAEAKRLAEQRE 685
Cdd:pfam17380 426 RAEQEEAR----------------QREVRRLEEERAREMERVRLEEQERQQQ--VERLRQQEEERKRKKLELEKEKRDRK 487
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 686 QERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQR---ELEEKKKKEEQQR 762
Cdd:pfam17380 488 RAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERrriQEQMRKATEERSR 567
|
250 260
....*....|....*....|....*..
gi 767968088 763 LAERQLQEEQEKKAKEAAGASKALNVT 789
Cdd:pfam17380 568 LEAMEREREMMRQIVESEKARAEYEAT 594
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
531-785 |
1.10e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 49.75 E-value: 1.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEE---AEQLRR----QKVEEDKR----RRLEEVK----LKREERLRKVLQARERVEQMKEEKKKQI 595
Cdd:PTZ00121 1117 AEEAKKKAEDARKAEEarkAEDARKaeeaRKAEDAKRveiaRKAEDARkaeeARKAEDAKKAEAARKAEEVRKAEELRKA 1196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 596 EQkfAQIDEKTEKAKEERLAEEKAKKKAAAKKME--EVEARRKQEEEAR-----RLRWLQQEEEERRHQELLQKKKEEEQ 668
Cdd:PTZ00121 1197 ED--ARKAEAARKAEEERKAEEARKAEDAKKAEAvkKAEEAKKDAEEAKkaeeeRNNEEIRKFEEARMAHFARRQAAIKA 1274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 669 ERLRKAAEAKRlAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK---E 745
Cdd:PTZ00121 1275 EEARKADELKK-AEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKaeaE 1353
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 767968088 746 QLQRELEEKKKKEEQQRLA---ERQLQEEQEKKAKEAAGASKA 785
Cdd:PTZ00121 1354 AAADEAEAAEEKAEAAEKKkeeAKKKADAAKKKAEEKKKADEA 1396
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
531-611 |
1.47e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 48.62 E-value: 1.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQ-RLENLRRKEEAEQLRRQKveEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKA 609
Cdd:PRK12704 56 KEALLEaKEEIHKLRNEFEKELRER--RNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEEL 133
|
..
gi 767968088 610 KE 611
Cdd:PRK12704 134 EE 135
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
531-778 |
2.53e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 48.43 E-value: 2.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLeevKLKREER-----LRKVLQARERVEQMKEEKKKQIEQKFAQIDEK 605
Cdd:pfam02463 168 KRKKKEALKKLIEETENLAELIIDLEELKLQEL---KLKEQAKkaleyYQLKEKLELEEEYLLYLDYLKLNEERIDLLQE 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 606 TEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRlrwLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQRE 685
Cdd:pfam02463 245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKK---LQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEK 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 686 QERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAE 765
Cdd:pfam02463 322 EKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401
|
250
....*....|...
gi 767968088 766 RQLQEEQEKKAKE 778
Cdd:pfam02463 402 EEEKEAQLLLELA 414
|
|
| tolA |
PRK09510 |
cell envelope integrity inner membrane protein TolA; Provisional |
542-681 |
3.99e-05 |
|
cell envelope integrity inner membrane protein TolA; Provisional
Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 47.11 E-value: 3.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 542 RRKEEaeqlRRQKVEEDKRRRLEEVKLKREERLRKVLQARERveqmKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKK 621
Cdd:PRK09510 75 KRAEE----QRKKKEQQQAEELQQKQAAEQERLKQLEKERLA----AQEQKKQAEEAAKQAALKQKQAEEAAAKAAAAAK 146
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767968088 622 KAAAKKMEEVEARRKQ-EEEARRLrwlqQEEEERRHQELLQKKKEEEQERLRKAAEAKRLA 681
Cdd:PRK09510 147 AKAEAEAKRAAAAAKKaAAEAKKK----AEAEAAKKAAAEAKKKAEAEAAAKAAAEAKKKA 203
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
526-787 |
1.04e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 46.20 E-value: 1.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 526 LRMDPKEKERQRLEN----LRRKEEAEQLRRQKVEE------DKRRRLEEVKLKREERLRKVLQARERVEQMKE---EKK 592
Cdd:TIGR02168 232 LRLEELREELEELQEelkeAEEELEELTAELQELEEkleelrLEVSELEEEIEELQKELYALANEISRLEQQKQilrERL 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 593 KQIEQKFAQID---EKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQE 669
Cdd:TIGR02168 312 ANLERQLEELEaqlEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQL 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 670 RLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERL----QAERELQEREKALRLQKE 745
Cdd:TIGR02168 392 ELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELeelqEELERLEEALEELREELE 471
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 767968088 746 QLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALN 787
Cdd:TIGR02168 472 EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK 513
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
531-777 |
1.21e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 46.12 E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEEAEQLRR-QKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEK---T 606
Cdd:pfam02463 748 EEEEEEKSRLKKEEKEEEKSELsLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLieqE 827
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 607 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ 686
Cdd:pfam02463 828 EKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQ 907
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 687 ERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE---RELQEREKALRLQKEQLQRE-----LEEKKKKE 758
Cdd:pfam02463 908 KLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEennKEEEEERNKRLLLAKEELGKvnlmaIEEFEEKE 987
|
250
....*....|....*....
gi 767968088 759 EQQRLAERQLQEEQEKKAK 777
Cdd:pfam02463 988 ERYNKDELEKERLEEEKKK 1006
|
|
| DUF4670 |
pfam15709 |
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ... |
526-644 |
1.52e-04 |
|
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.
Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 45.33 E-value: 1.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 526 LRMDPKEKERQRLENLRRKEeaeQLRRQKVEEDKRRRLEEVKLKREERLRKVLQ-ARERVEQMKEEKKKQIEQKFAQIDE 604
Cdd:pfam15709 391 LRKQRLEEERQRQEEEERKQ---RLQLQAAQERARQQQEEFRRKLQELQRKKQQeEAERAEAEKQRQKELEMQLAEEQKR 467
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 767968088 605 KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 644
Cdd:pfam15709 468 LMEMAEEERLEYQRQKQEAEEKARLEAEERRQKEEEAARL 507
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
532-780 |
1.81e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.43 E-value: 1.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQkfaqIDEKTEKAKE 611
Cdd:TIGR02168 739 EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREA----LDELRAELTL 814
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 612 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLrwlqqeeeerrhqellqKKKEEEQERLRKAAEAKRLAEQREQERREQ 691
Cdd:TIGR02168 815 LNEEAANLRERLESLERRIAATERRLEDLEEQI-----------------EELSEDIESLAAEIEELEELIEELESELEA 877
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 692 ERREQERREQERREQERREQERQLAEQERRREQERLQAER-ELQEREKALRLQKEQLQRELEEKkkkeeQQRLAERQLQE 770
Cdd:TIGR02168 878 LLNERASLEEALALLRSELEELSEELRELESKRSELRRELeELREKLAQLELRLEGLEVRIDNL-----QERLSEEYSLT 952
|
250
....*....|
gi 767968088 771 EQEKKAKEAA 780
Cdd:TIGR02168 953 LEEAEALENK 962
|
|
| DUF4670 |
pfam15709 |
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ... |
538-683 |
1.90e-04 |
|
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.
Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 44.94 E-value: 1.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 538 LENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEE 617
Cdd:pfam15709 325 LEKREQEKASRDRLRAERAEMRRLEVERKRREQEEQRRLQQEQLERAEKMREELELEQQRRFEEIRLRKQRLEEERQRQE 404
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767968088 618 KAKKKAAAKKMEEVE-ARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQ 683
Cdd:pfam15709 405 EEERKQRLQLQAAQErARQQQEEFRRKLQELQRKKQQEEAERAEAEKQRQKELEMQLAEEQKRLMEM 471
|
|
| tolA_full |
TIGR02794 |
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ... |
521-678 |
4.33e-04 |
|
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 43.68 E-value: 4.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 521 KRNTPLRMDPKEKERQRLENLRRkeEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERveqmKEEKKKQIEQKFA 600
Cdd:TIGR02794 53 NRIQQQKKPAAKKEQERQKKLEQ--QAEEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQ----AEEKQKQAEEAKA 126
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767968088 601 QiDEKTEKAKEErlaeekakkkAAAKKMEEVEARRKQEEEARrlrwlqqeeeerrHQELLQKKKEEEQERLRKAAEAK 678
Cdd:TIGR02794 127 K-QAAEAKAKAE----------AEAERKAKEEAAKQAEEEAK-------------AKAAAEAKKKAEEAKKKAEAEAK 180
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
536-667 |
6.95e-04 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 43.28 E-value: 6.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 536 QRLENLRRkeEAEQlrrqkveedKRRRLEEvKLKREERLRKVLQAR-ERVEQMKEEKKKQIEQKFAQIdekTEKAKEERL 614
Cdd:PRK00409 523 ASLEELER--ELEQ---------KAEEAEA-LLKEAEKLKEELEEKkEKLQEEEDKLLEEAEKEAQQA---IKEAKKEAD 587
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 767968088 615 AEEKAKKKAAAKKMEEVeaRRKQEEEARRLrwLQQEEEERRHQELLQKKKEEE 667
Cdd:PRK00409 588 EIIKELRQLQKGGYASV--KAHELIEARKR--LNKANEKKEKKKKKQKEKQEE 636
|
|
| MAP7 |
pfam05672 |
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ... |
527-612 |
1.00e-03 |
|
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.
Pssm-ID: 461709 [Multi-domain] Cd Length: 153 Bit Score: 40.79 E-value: 1.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 527 RMDPKEKERQRLENLRRKEEAEQLRRqkvEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQkfaQIDEKT 606
Cdd:pfam05672 34 RLEKEEEERLRKEELRRRAEEERARR---EEEARRLEEERRREEEERQRKAEEEAEEREQREQEEQERLQK---QKEEAE 107
|
....*.
gi 767968088 607 EKAKEE 612
Cdd:pfam05672 108 AKAREE 113
|
|
| RNase_Y_N |
pfam12072 |
RNase Y N-terminal region; |
544-611 |
1.29e-03 |
|
RNase Y N-terminal region;
Pssm-ID: 463456 [Multi-domain] Cd Length: 201 Bit Score: 41.02 E-value: 1.29e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767968088 544 KEEAEQLRRQKVEEDKRRR-----LEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 611
Cdd:pfam12072 59 KEEIHKLRAEAERELKERRnelqrQERRLLQKEETLDRKDESLEKKEESLEKKEKELEAQQQQLEEKEEELEE 131
|
|
| PRK05035 |
PRK05035 |
electron transport complex protein RnfC; Provisional |
531-785 |
1.46e-03 |
|
electron transport complex protein RnfC; Provisional
Pssm-ID: 235334 [Multi-domain] Cd Length: 695 Bit Score: 42.24 E-value: 1.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEEAEQ---LRRQKVEEDKRRRLEEVKLKREERLRK----VLQARERVEQMKEEKKKQIEQKFAQID 603
Cdd:PRK05035 435 KAEIRAIEQEKKKAEEAKArfeARQARLEREKAAREARHKKAAEARAAKdkdaVAAALARVKAKKAAATQPIVIKAGARP 514
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 604 EKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRwlqqeEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQ 683
Cdd:PRK05035 515 DNSAVIAAREARKAQARARQAEKQAAAAADPKKAAVAAAIAR-----AKAKKAAQQAANAEAEEEVDPKKAAVAAAIARA 589
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 684 REQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKalrlqKEQLQRELEEKK-KKEEQQR 762
Cdd:PRK05035 590 KAKKAAQQAASAEPEEQVAEVDPKKAAVAAAIARAKAKKAEQQANAEPEEPVDPR-----KAAVAAAIARAKaRKAAQQQ 664
|
250 260
....*....|....*....|...
gi 767968088 763 LAERQLQEEQEKKAKEAAGASKA 785
Cdd:PRK05035 665 ANAEPEEAEDPKKAAVAAAIARA 687
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
531-612 |
1.60e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.07 E-value: 1.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQ---RLENLRRKEEAEQLRRQKVE------EDKRRRLEEVKLKREERLRKVL-----QARERV-EQMKEEKKKQI 595
Cdd:PRK12704 92 LQKEENldrKLELLEKREEELEKKEKELEqkqqelEKKEEELEELIEEQLQELERISgltaeEAKEILlEKVEEEARHEA 171
|
90
....*....|....*..
gi 767968088 596 eqkFAQIDEKTEKAKEE 612
Cdd:PRK12704 172 ---AVLIKEIEEEAKEE 185
|
|
| ERM_helical |
pfam20492 |
Ezrin/radixin/moesin, alpha-helical domain; The ERM family consists of three closely-related ... |
537-645 |
1.69e-03 |
|
Ezrin/radixin/moesin, alpha-helical domain; The ERM family consists of three closely-related proteins, ezrin, radixin and moesin. Ezrin was first identified as a constituent of microvilli, radixin as a barbed, end-capping actin-modulating protein from isolated junctional fractions, and moesin as a heparin binding protein. A tumour suppressor molecule responsible for neurofibromatosis type 2 (NF2) is highly similar to ERM proteins and has been designated merlin (moesin-ezrin-radixin-like protein). ERM molecules contain 3 domains, an N-terminal globular domain, an extended alpha-helical domain and a charged C-terminal domain (pfam00769). Ezrin, radixin and merlin also contain a polyproline linker region between the helical and C-terminal domains. The N-terminal domain is highly conserved and is also found in merlin, band 4.1 proteins and members of the band 4.1 superfamily, designated the FERM domain. ERM proteins crosslink actin filaments with plasma membranes. They co-localize with CD44 at actin filament plasma membrane interaction sites, associating with CD44 via their N-terminal domains and with actin filaments via their C-terminal domains. This is the alpha-helical domain, which is involved in intramolecular masking of protein-protein interaction sites, regulating the activity of this proteins.
Pssm-ID: 466641 [Multi-domain] Cd Length: 120 Bit Score: 39.13 E-value: 1.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 537 RLENLRRKEEAEQLRRQKVEEDKR-----RRLEEVKLKREERLRKVLQARERVEQmkeeKKKQIEQKFAQIDEKTEKAKE 611
Cdd:pfam20492 1 REEAEREKQELEERLKQYEEETKKaqeelEESEETAEELEEERRQAEEEAERLEQ----KRQEAEEEKERLEESAEMEAE 76
|
90 100 110
....*....|....*....|....*....|....
gi 767968088 612 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR 645
Cdd:pfam20492 77 EKEQLEAELAEAQEEIARLEEEVERKEEEARRLQ 110
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
520-679 |
1.90e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 42.03 E-value: 1.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 520 IKRNTPLRMDPKEKERQRLENLRRKE-----------EAEQLRRQKVEEDKRRRLE---EVKLKREERLRKVLQARERVE 585
Cdd:pfam17380 344 MERERELERIRQEERKRELERIRQEEiameisrmrelERLQMERQQKNERVRQELEaarKVKILEEERQRKIQQQKVEME 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 586 QMKEEKKKQIEqkfaqidEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKK- 664
Cdd:pfam17380 424 QIRAEQEEARQ-------REVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKi 496
|
170
....*....|....*..
gi 767968088 665 --EEEQERLRKAAEAKR 679
Cdd:pfam17380 497 leKELEERKQAMIEEER 513
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
141-287 |
1.96e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 42.00 E-value: 1.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 141 PSSPTPESPTMLTK---KPEDNHTQCQLVPVVEIGISERQNAEQHVTQLMSTEPLPRTLSPTPASATAPTSQ----GIPT 213
Cdd:PRK08691 380 PSAQTAEKETAAKKpqpRPEAETAQTPVQTASAAAMPSEGKTAGPVSNQENNDVPPWEDAPDEAQTAAGTAQtsakSIQT 459
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767968088 214 SDEESTPKK---SKARILESITVSSLMATPQDPKGQGVGTGRSASKLRIAQVSPG-PRDSPAFPDSPWRERVLAPILP 287
Cdd:PRK08691 460 ASEAETPPEnqvSKNKAADNETDAPLSEVPSENPIQATPNDEAVETETFAHEAPAePFYGYGFPDNDCPPEDGAEIPP 537
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
448-775 |
1.98e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 42.27 E-value: 1.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 448 RRKRSYKQAVSELDEEQHLEDEELqpprsktpsspcpaskvVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLR 527
Cdd:pfam02463 198 QELKLKEQAKKALEYYQLKEKLEL-----------------EEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEI 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 528 MDPKEKERQRLENlrRKEEAEQLRRQKVEEDK--RRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQI--- 602
Cdd:pfam02463 261 EKEEEKLAQVLKE--NKEEEKEKKLQEEELKLlaKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEeie 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 603 -DEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLA 681
Cdd:pfam02463 339 eLEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLE 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 682 EQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 761
Cdd:pfam02463 419 DLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEER 498
|
330
....*....|....
gi 767968088 762 RLAERQLQEEQEKK 775
Cdd:pfam02463 499 SQKESKARSGLKVL 512
|
|
| tolA_full |
TIGR02794 |
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ... |
531-681 |
2.21e-03 |
|
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 41.37 E-value: 2.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEEAEQLRRQKvEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAK 610
Cdd:TIGR02794 84 RAAEQARQKELEQRAAAEKAAKQA-EQAAKQAEEKQKQAEEAKAKQAAEAKAKAEAEAERKAKEEAAKQAEEEAKAKAAA 162
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767968088 611 EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQellqKKKEEEQERLRKAAEAKRLA 681
Cdd:TIGR02794 163 EAKKKAEEAKKKAEAEAKAKAEAEAKAKAEEAKAKAEAAKAKAAAEA----AAKAEAEAAAAAAAEAERKA 229
|
|
| PTZ00266 |
PTZ00266 |
NIMA-related protein kinase; Provisional |
527-614 |
2.74e-03 |
|
NIMA-related protein kinase; Provisional
Pssm-ID: 173502 [Multi-domain] Cd Length: 1021 Bit Score: 41.65 E-value: 2.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 527 RMDPKEKERQRLE--NLRRKE-EAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQID 603
Cdd:PTZ00266 429 RVDKDHAERARIEkeNAHRKAlEMKILEKKRIERLEREERERLERERMERIERERLERERLERERLERDRLERDRLDRLE 508
|
90
....*....|..
gi 767968088 604 -EKTEKAKEERL 614
Cdd:PTZ00266 509 rERVDRLERDRL 520
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
531-787 |
3.07e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.59 E-value: 3.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEEaeqlRRQKVEEDKRRRLEEVKLKREER-----LRKVLQARERVEQMKEEKK--KQIEQKFAQID 603
Cdd:TIGR02169 172 KEKALEELEEVEENIE----RLDLIIDEKRQQLERLRREREKAeryqaLLKEKREYEGYELLKEKEAleRQKEAIERQLA 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 604 EKT-EKAK-EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLA 681
Cdd:TIGR02169 248 SLEeELEKlTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 682 EQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE----RELQEREKALRLQKEQLQRELEEKKKK 757
Cdd:TIGR02169 328 EAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVdkefAETRDELKDYREKLEKLKREINELKRE 407
|
250 260 270
....*....|....*....|....*....|
gi 767968088 758 EEQQRLAERQLQEEQEKKAKEAAGASKALN 787
Cdd:TIGR02169 408 LDRLQEELQRLSEELADLNAAIAGIEAKIN 437
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
531-786 |
3.44e-03 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 40.67 E-value: 3.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLEnlrrKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAK 610
Cdd:pfam13868 83 EEREQKRQE----EYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERIL 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 611 EERLAEEKAKKKAAAKKMeevEARRKQEEEARRLRWLQQEEEERRHQ--ELLQKKKEEEQERLRKAAEAKRLAEQREQER 688
Cdd:pfam13868 159 EYLKEKAEREEEREAERE---EIEEEKEREIARLRAQQEKAQDEKAErdELRAKLYQEEQERKERQKEREEAEKKARQRQ 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 689 REQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREkalRLQKEQLQRELEEKKKKEEQQRLAERQL 768
Cdd:pfam13868 236 ELQQAREEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKR---RMKRLEHRRELEKQIEEREEQRAAEREE 312
|
250
....*....|....*...
gi 767968088 769 QEEQEKKAKEAAGASKAL 786
Cdd:pfam13868 313 ELEEGERLREEEAERRER 330
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
429-678 |
3.66e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 41.26 E-value: 3.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 429 QQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQhLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTP 508
Cdd:pfam17380 319 EEAEKARQAEMDRQAAIYAEQERMAMERERELERIR-QEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQE 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 509 TSAPRSVMKSFIKRNTPLRMDPKEKERQRLEnlrrKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMK 588
Cdd:pfam17380 398 LEAARKVKILEEERQRKIQQQKVEMEQIRAE----QEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERK 473
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 589 EEK----KKQIEQKFAQIDEKT--EKAKEERLAEEKAKKKAAAKKMEEVEARRKQ--EEEARRlrwlQQEEEERRHQELL 660
Cdd:pfam17380 474 RKKleleKEKRDRKRAEEQRRKilEKELEERKQAMIEEERKRKLLEKEMEERQKAiyEEERRR----EAEEERRKQQEME 549
|
250
....*....|....*...
gi 767968088 661 QKKKEEEQerLRKAAEAK 678
Cdd:pfam17380 550 ERRRIQEQ--MRKATEER 565
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
532-645 |
3.87e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.08 E-value: 3.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 532 EKERQRLENLRRKEEAEQLRRQKVEEdkRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 611
Cdd:COG1196 666 SRRELLAALLEAEAELEELAERLAEE--ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743
|
90 100 110
....*....|....*....|....*....|....
gi 767968088 612 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR 645
Cdd:COG1196 744 EEELLEEEALEELPEPPDLEELERELERLEREIE 777
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
562-678 |
5.99e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 40.58 E-value: 5.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 562 RLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEErlaeekakkkaaaKKMEEVEARRKQEEEA 641
Cdd:PRK00409 524 SLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKE-------------AQQAIKEAKKEADEII 590
|
90 100 110
....*....|....*....|....*....|....*..
gi 767968088 642 RRLRWLQQEEEERRHQELLQkkkeEEQERLRKAAEAK 678
Cdd:PRK00409 591 KELRQLQKGGYASVKAHELI----EARKRLNKANEKK 623
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
531-780 |
6.65e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 40.43 E-value: 6.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQrLENLRRK-EEAEQLRRQKVE-EDKRRRLEEVKLKR-EERLRKVLQARERVEQMKEEKKKQIEQKFAQIDE-KT 606
Cdd:TIGR02168 196 NELERQ-LKSLERQaEKAERYKELKAElRELELALLVLRLEElREELEELQEELKEAEEELEELTAELQELEEKLEElRL 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 607 EKAK-EERLAEEKAKKKAAAKKMEEVEaRRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERL-RKAAEAKRLAEQR 684
Cdd:TIGR02168 275 EVSElEEEIEELQKELYALANEISRLE-QQKQILRERLANLERQLEELEAQLEELESKLDELAEELaELEEKLEELKEEL 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 685 EQERREQERREQERREQERREQERREQERQLAEQ-ERRREQERLQAER---------ELQEREKALRLQKEQLQRELEEK 754
Cdd:TIGR02168 354 ESLEAELEELEAELEELESRLEELEEQLETLRSKvAQLELQIASLNNEierlearleRLEDRRERLQQEIEELLKKLEEA 433
|
250 260
....*....|....*....|....*.
gi 767968088 755 KKKEEQQRLAERQLQEEQEKKAKEAA 780
Cdd:TIGR02168 434 ELKELQAELEELEEELEELQEELERL 459
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
531-777 |
7.09e-03 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 39.52 E-value: 7.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKfaQIDEKTEKAK 610
Cdd:pfam13868 59 EEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQR--QLREEIDEFN 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 611 EERLAEEKAKKKAAAKKMEEVE------ARRKQEEEARRLRwlqqeeeerrhqelLQKKKEEEQERLRKAAEAKRLAEQR 684
Cdd:pfam13868 137 EEQAEWKELEKEEEREEDERILeylkekAEREEEREAEREE--------------IEEEKEREIARLRAQQEKAQDEKAE 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 685 EQERREQERREQERREQERREQErreqerqlAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 764
Cdd:pfam13868 203 RDELRAKLYQEEQERKERQKERE--------EAEKKARQRQELQQAREEQIELKERRLAEEAEREEEEFERMLRKQAEDE 274
|
250
....*....|...
gi 767968088 765 ERQLQEEQEKKAK 777
Cdd:pfam13868 275 EIEQEEAEKRRMK 287
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
142-513 |
7.94e-03 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 39.90 E-value: 7.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 142 SSPTPE------SPTMLTKKPEDNHTqcqlvpvveigisERQNAEQHVTQLMSTEPLPRTLSPTPAsATAPTSQGIPTSD 215
Cdd:pfam05109 474 TSPTPAgttsgaSPVTPSPSPRDNGT-------------ESKAPDMTSPTSAVTTPTPNATSPTPA-VTTPTPNATSPTL 539
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 216 EESTPKKSKARILESITVSSLMATPQDPKGQGVGTGRSASKLRIAQVSPGPrDSPAFPDSPWRERVLAPILPDNFSTPTG 295
Cdd:pfam05109 540 GKTSPTSAVTTPTPNATSPTPAVTTPTPNATIPTLGKTSPTSAVTTPTPNA-TSPTVGETSPQANTTNHTLGGTSSTPVV 618
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 296 SrtdsQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVrraSRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQ 375
Cdd:pfam05109 619 T----SPPKNATSAVTTGQHNITSSSTSSMSLRPSSI---SETLSPSTSDNSTSHMPLLTSAHPTGGENITQVTPASTST 691
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 376 KEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQ 455
Cdd:pfam05109 692 HHVSTSSPAPRPGTTSQASGPGNSSTSTKPGEVNVTKGTPPKNATSPQAPSGQKTAVPTVTSTGGKANSTTGGKHTTGHG 771
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767968088 456 AVSELDEEQHLEDEElQPPRSK---TPSSPCPASKVVRPLRTFLH---TVQRNQMLMTPTSAPR 513
Cdd:pfam05109 772 ARTSTEPTTDYGGDS-TTPRTRynaTTYLPPSTSSKLRPRWTFTSppvTTAQATVPVPPTSQPR 834
|
|
| Caldesmon |
pfam02029 |
Caldesmon; |
406-611 |
8.11e-03 |
|
Caldesmon;
Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 39.85 E-value: 8.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 406 TEIANSTPNpKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSY---------KQAVSELDEEQHLEDEELQPPR- 475
Cdd:pfam02029 94 ADEKESVAE-RKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREKEYqenkwstevRQAEEEGEEEEDKSEEAEEVPTe 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 476 --SKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRM------DPKEKE-------RQRLEN 540
Cdd:pfam02029 173 nfAKEEVKDEKIKKEKKVKYESKVFLDQKRGHPEVKSQNGEEEVTKLKVTTKRRQgglsqsQEREEEaevfleaEQKLEE 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 541 LRRK------EEAEQLRRQK------VEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK---KKQIEQKFAQIDEK 605
Cdd:pfam02029 253 LRRRrqekesEEFEKLRQKQqeaeleLEELKKKREERRKLLEEEEQRRKQEEAERKLREEEEKrrmKEEIERRRAEAAEK 332
|
....*.
gi 767968088 606 TEKAKE 611
Cdd:pfam02029 333 RQKLPE 338
|
|
| MAP7 |
pfam05672 |
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ... |
534-670 |
8.19e-03 |
|
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.
Pssm-ID: 461709 [Multi-domain] Cd Length: 153 Bit Score: 38.10 E-value: 8.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 534 ERQRLENLRRKEEaEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEER 613
Cdd:pfam05672 18 EKRRQAREQRERE-EQERLEKEEEERLRKEELRRRAEEERARREEEARRLEEERRREEEERQRKAEEEAEEREQREQEEQ 96
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 767968088 614 LAEEKAKKkaaakkmeevEARRKQEEEARRLRwlqqeeeeRRHQELLQKKKEEEQER 670
Cdd:pfam05672 97 ERLQKQKE----------EAEAKAREEAERQR--------QEREKIMQQEEQERLER 135
|
|
| PRK12585 |
PRK12585 |
putative monovalent cation/H+ antiporter subunit G; Reviewed |
520-613 |
8.64e-03 |
|
putative monovalent cation/H+ antiporter subunit G; Reviewed
Pssm-ID: 183610 Cd Length: 197 Bit Score: 38.51 E-value: 8.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767968088 520 IKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKF 599
Cdd:PRK12585 101 IRIRDQLRSVKKDDIKKKKSLIIRQEQIEKARQEREELEERMEWERREEKIDEREDQEEQEREREEQTIEEQSDDSEHEI 180
|
90
....*....|....
gi 767968088 600 AQIDEKTEKAKEER 613
Cdd:PRK12585 181 IEQDESETESDDDK 194
|
|
| |
