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Conserved domains on  [gi|767967878|ref|XP_011543214|]
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triokinase/FMN cyclase isoform X1 [Homo sapiens]

Protein Classification

dihydroxyacetone kinase family protein( domain architecture ID 1001500)

dihydroxyacetone kinase family protein similar to human triokinase/FMN cyclase and dihydroxyacetone kinase subunit L (DhaL), which is the ADP-binding subunit of dihydroxyacetone kinase that catalyzes the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone via a phosphoryl group transfer from DhaL-ATP

Gene Ontology:  GO:0004371|GO:0006071|GO:0005524
PubMed:  16505971|15476397

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PRK14479 super family cl29418
dihydroxyacetone kinase; Provisional
 50-572 0e+00

dihydroxyacetone kinase; Provisional


The actual alignment was detected with superfamily member TIGR02361:

Pssm-ID: 475197 [Multi-domain]  Cd Length: 574  Bit Score: 679.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878   50 KKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 129
Cdd:TIGR02361   1 KHFVNDPEHLVDDALKGLVAANPGLQLLESRKVVYRRDLN--KDKVSLISGGGSGHEPAHAGFVGKGMLTAAVAGDVFAS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  130 PAVGSILAAIRAVAQaGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLK--KAGRRGLCGTVLIH 207
Cdd:TIGR02361  79 PSTKQILAAIRAVVG-SEAGTLLIVKNYTGDRLNFGLAAEKAKAEGYNVEMVIVGDDVSVGRKKggLVGRRGLAGTVLVH 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  208 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGSKPTF-ELSADEVELGLGIHGEAGVRRIKMA-TADEIVK 285
Cdd:TIGR02361 158 KIAGAAAARGLSLAEVAKVAQAAADNLVTIGASLDHCHVPGETEAEpELKEDEMELGMGIHNEPGAKRISPIpSSDLVVQ 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  286 LMLDHMTNTTNA-SHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARAL-VGTFMSALEMPGISLTLL 363
Cdd:TIGR02361 238 LMLKKLLDETDKrSYVKFNEGDEVVLLVNNLGGVSNLELGIIADEVVEQLALHYNIIPVRIySGTFMTSLNGPGFSITLL 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  364 LVDE---PLLKLIDAETTAAAWPNVAAVSITGRKRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNA 440
Cdd:TIGR02361 318 NATEagkSILDLLDAPTEAPGWPVAAYSSKPWREKREVVSSSAPELIEETAVRSYDPQLVAAILESGCAALLELEPHLTK 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  441 LDRAAGDGDCGTTHSRAARAIQEWLK-EGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKAKTSLP---- 515
Cdd:TIGR02361 398 LDTKAGDGDCGSTLARGAEAILELLKsKKLPLNDPATLLAQISDVVEGVMGGTSGALYSIFFSAAAQSLKQNASKKeeit 477

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767967878  516 --AWSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPgadllqvLTKAVKA 572
Cdd:TIGR02361 478 peAWAAALKTALDALYKYTGARPGDRTMIDALQPFVEALEAGKSN-------LNAAVKA 529
 
Name Accession Description Interval E-value
dak_ATP TIGR02361
dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of ...
 50-572 0e+00

dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of dihydroxyacetone kinase (also called glycerone kinase) that uses ATP (2.7.1.29) as the phosphate donor, rather than a phosphoprotein as in E. coli. This form is composed of a single chain with separable domains homologous to the K and L subunits of the E. coli enzyme, and is found in yeasts and other eukaryotes and in some bacteria, including Citrobacter freundii. The member from tomato has been shown to phosphorylate dihydroxyacetone, 3,4-dihydroxy-2-butanone, and some other aldoses and ketoses ().


Pssm-ID: 274097 [Multi-domain]  Cd Length: 574  Bit Score: 679.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878   50 KKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 129
Cdd:TIGR02361   1 KHFVNDPEHLVDDALKGLVAANPGLQLLESRKVVYRRDLN--KDKVSLISGGGSGHEPAHAGFVGKGMLTAAVAGDVFAS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  130 PAVGSILAAIRAVAQaGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLK--KAGRRGLCGTVLIH 207
Cdd:TIGR02361  79 PSTKQILAAIRAVVG-SEAGTLLIVKNYTGDRLNFGLAAEKAKAEGYNVEMVIVGDDVSVGRKKggLVGRRGLAGTVLVH 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  208 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGSKPTF-ELSADEVELGLGIHGEAGVRRIKMA-TADEIVK 285
Cdd:TIGR02361 158 KIAGAAAARGLSLAEVAKVAQAAADNLVTIGASLDHCHVPGETEAEpELKEDEMELGMGIHNEPGAKRISPIpSSDLVVQ 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  286 LMLDHMTNTTNA-SHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARAL-VGTFMSALEMPGISLTLL 363
Cdd:TIGR02361 238 LMLKKLLDETDKrSYVKFNEGDEVVLLVNNLGGVSNLELGIIADEVVEQLALHYNIIPVRIySGTFMTSLNGPGFSITLL 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  364 LVDE---PLLKLIDAETTAAAWPNVAAVSITGRKRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNA 440
Cdd:TIGR02361 318 NATEagkSILDLLDAPTEAPGWPVAAYSSKPWREKREVVSSSAPELIEETAVRSYDPQLVAAILESGCAALLELEPHLTK 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  441 LDRAAGDGDCGTTHSRAARAIQEWLK-EGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKAKTSLP---- 515
Cdd:TIGR02361 398 LDTKAGDGDCGSTLARGAEAILELLKsKKLPLNDPATLLAQISDVVEGVMGGTSGALYSIFFSAAAQSLKQNASKKeeit 477

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767967878  516 --AWSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPgadllqvLTKAVKA 572
Cdd:TIGR02361 478 peAWAAALKTALDALYKYTGARPGDRTMIDALQPFVEALEAGKSN-------LNAAVKA 529
PRK14479 PRK14479
dihydroxyacetone kinase; Provisional
 50-572 3.09e-164

dihydroxyacetone kinase; Provisional


Pssm-ID: 237723 [Multi-domain]  Cd Length: 568  Bit Score: 481.62  E-value: 3.09e-164
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  50 KKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 129
Cdd:PRK14479   2 KKLINDPSTFVEEMLEGFVAAHPDLVRLVPGGVVRRTPTP--EGKVAVVSGGGSGHEPAFAGYVGPGMLDAAVCGNVFTS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 130 PAVGSILAAIRAVAQAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAF-TVLKKAGRRGLCGTVLIHK 208
Cdd:PRK14479  80 PSADQVYAAIRAADGGA--GVLLIVGNYAGDVMNFGLAAELARAEGIDVRTVVVTDDVASaPSGETAGRRGIAGTVLVFK 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 209 VAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGS-KPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLM 287
Cdd:PRK14479 158 IAGAAAEAGLDLDEVAAIARKANARTRSMGVALDGCTLPGAgEPLFTLPEGEMELGLGIHGEPGIEREALPTADELADRL 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 288 LDHMTNttnasHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVDE 367
Cdd:PRK14479 238 VDRILA-----DLPLGAGERVAVLVNGLGATPYEELFVVYGAVARLLAARGITVVRPEVGEFVTSLDMAGASLTLMKLDD 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 368 PLLKLIDAETTAAAWPNVAAVSITGRkRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNALDRAAGD 447
Cdd:PRK14479 313 ELEELWDAPADTPAFRRGGAVEPVEY-VEAAEEDDAEEPPRASKASRATAANLVAALDAVAEALIDNEDELGELDAVAGD 391

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 448 GDCGTTHSRAARAIQEWLKEGPPP-ASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPL--KAKTSLPAWSAAMDAG 524
Cdd:PRK14479 392 GDHGIGMARGSKAALAAARAAVEAgAGAGSVLAAAGDAWADHAGGTSGPLWGTALRAAGKALgdKDEPTAADFAAAVRAA 471

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*...
gi 767967878 525 LEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKA 572
Cdd:PRK14479 472 VDAIQELGGAQVGDKTMVDALVPFADALEAAAAAGADLAEAWAAAAEA 519
Dak1 pfam02733
Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.
 65-381 1.30e-147

Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.


Pssm-ID: 460667  Cd Length: 312  Bit Score: 429.56  E-value: 1.30e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878   65 AGLVACNPN-LQLLQGHRVALRSDlDSLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTSPAVGSILAAIRAVA 143
Cdd:pfam02733   1 EGLAAAHPDlLRLVPGPRVVVRAD-APPKGKVALISGGGSGHEPAHAGYVGKGMLDAAVPGEVFASPSPDQILAAIKAVD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  144 QAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAF-TVLKKAGRRGLCGTVLIHKVAGALAEAGVGLEE 222
Cdd:pfam02733  80 GGA--GVLLIVKNYTGDVLNFGMAAELARAEGIKVETVVVGDDVAVgDSGGTVGRRGVAGTVLVHKIAGAAAEAGASLDE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  223 IAKQVNVVAKAMGTLGVSLSSCSVPG-SKPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLMLDHMTNTTnashvP 301
Cdd:pfam02733 158 VARLAEKVNANTRTMGVALSPCTVPGaGKPTFELGEDEMELGMGIHGEPGVKREKLKPADELVEELLDKLLDDD-----P 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  302 VQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVDEPLLKLIDAETTAAA 381
Cdd:pfam02733 233 LLPGDEVAVLVNGLGGTPLLELYIVYRRVLELLEEKGIKVVRSLVGEYMTSLDMAGFSLTLLKLDDELLELLDAPVDTPA 312
DAK1 COG2376
Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is ...
 424-572 4.95e-19

Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441943 [Multi-domain]  Cd Length: 206  Bit Score: 85.64  E-value: 4.95e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 424 LERVCSTLLGLEEHLNALDRAAGDGDCGTTHSRAARAIQEwlKEGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTA 503
Cdd:COG2376    1 MKAVADVIAENRKFLNDLDAVVGDGDHGINMARGFDAVRA--ALDAAPADPGVVLRAAGMKVASVVGGGSGGLVGTGFLD 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767967878 504 AAQPLKAKTSLPA--WSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKA 572
Cdd:COG2376   79 AAVALKGETSPTAdqVAAALRAADEGIQGRGVAYTGDKTNFDAAAPAAEAIEEAVAAGTAAAAALDEAAAA 149
 
Name Accession Description Interval E-value
dak_ATP TIGR02361
dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of ...
 50-572 0e+00

dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of dihydroxyacetone kinase (also called glycerone kinase) that uses ATP (2.7.1.29) as the phosphate donor, rather than a phosphoprotein as in E. coli. This form is composed of a single chain with separable domains homologous to the K and L subunits of the E. coli enzyme, and is found in yeasts and other eukaryotes and in some bacteria, including Citrobacter freundii. The member from tomato has been shown to phosphorylate dihydroxyacetone, 3,4-dihydroxy-2-butanone, and some other aldoses and ketoses ().


Pssm-ID: 274097 [Multi-domain]  Cd Length: 574  Bit Score: 679.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878   50 KKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 129
Cdd:TIGR02361   1 KHFVNDPEHLVDDALKGLVAANPGLQLLESRKVVYRRDLN--KDKVSLISGGGSGHEPAHAGFVGKGMLTAAVAGDVFAS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  130 PAVGSILAAIRAVAQaGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLK--KAGRRGLCGTVLIH 207
Cdd:TIGR02361  79 PSTKQILAAIRAVVG-SEAGTLLIVKNYTGDRLNFGLAAEKAKAEGYNVEMVIVGDDVSVGRKKggLVGRRGLAGTVLVH 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  208 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGSKPTF-ELSADEVELGLGIHGEAGVRRIKMA-TADEIVK 285
Cdd:TIGR02361 158 KIAGAAAARGLSLAEVAKVAQAAADNLVTIGASLDHCHVPGETEAEpELKEDEMELGMGIHNEPGAKRISPIpSSDLVVQ 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  286 LMLDHMTNTTNA-SHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARAL-VGTFMSALEMPGISLTLL 363
Cdd:TIGR02361 238 LMLKKLLDETDKrSYVKFNEGDEVVLLVNNLGGVSNLELGIIADEVVEQLALHYNIIPVRIySGTFMTSLNGPGFSITLL 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  364 LVDE---PLLKLIDAETTAAAWPNVAAVSITGRKRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNA 440
Cdd:TIGR02361 318 NATEagkSILDLLDAPTEAPGWPVAAYSSKPWREKREVVSSSAPELIEETAVRSYDPQLVAAILESGCAALLELEPHLTK 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  441 LDRAAGDGDCGTTHSRAARAIQEWLK-EGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKAKTSLP---- 515
Cdd:TIGR02361 398 LDTKAGDGDCGSTLARGAEAILELLKsKKLPLNDPATLLAQISDVVEGVMGGTSGALYSIFFSAAAQSLKQNASKKeeit 477

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767967878  516 --AWSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPgadllqvLTKAVKA 572
Cdd:TIGR02361 478 peAWAAALKTALDALYKYTGARPGDRTMIDALQPFVEALEAGKSN-------LNAAVKA 529
PRK14479 PRK14479
dihydroxyacetone kinase; Provisional
 50-572 3.09e-164

dihydroxyacetone kinase; Provisional


Pssm-ID: 237723 [Multi-domain]  Cd Length: 568  Bit Score: 481.62  E-value: 3.09e-164
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  50 KKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 129
Cdd:PRK14479   2 KKLINDPSTFVEEMLEGFVAAHPDLVRLVPGGVVRRTPTP--EGKVAVVSGGGSGHEPAFAGYVGPGMLDAAVCGNVFTS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 130 PAVGSILAAIRAVAQAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAF-TVLKKAGRRGLCGTVLIHK 208
Cdd:PRK14479  80 PSADQVYAAIRAADGGA--GVLLIVGNYAGDVMNFGLAAELARAEGIDVRTVVVTDDVASaPSGETAGRRGIAGTVLVFK 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 209 VAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGS-KPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLM 287
Cdd:PRK14479 158 IAGAAAEAGLDLDEVAAIARKANARTRSMGVALDGCTLPGAgEPLFTLPEGEMELGLGIHGEPGIEREALPTADELADRL 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 288 LDHMTNttnasHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVDE 367
Cdd:PRK14479 238 VDRILA-----DLPLGAGERVAVLVNGLGATPYEELFVVYGAVARLLAARGITVVRPEVGEFVTSLDMAGASLTLMKLDD 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 368 PLLKLIDAETTAAAWPNVAAVSITGRkRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNALDRAAGD 447
Cdd:PRK14479 313 ELEELWDAPADTPAFRRGGAVEPVEY-VEAAEEDDAEEPPRASKASRATAANLVAALDAVAEALIDNEDELGELDAVAGD 391

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 448 GDCGTTHSRAARAIQEWLKEGPPP-ASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPL--KAKTSLPAWSAAMDAG 524
Cdd:PRK14479 392 GDHGIGMARGSKAALAAARAAVEAgAGAGSVLAAAGDAWADHAGGTSGPLWGTALRAAGKALgdKDEPTAADFAAAVRAA 471

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*...
gi 767967878 525 LEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKA 572
Cdd:PRK14479 472 VDAIQELGGAQVGDKTMVDALVPFADALEAAAAAGADLAEAWAAAAEA 519
Dak1 pfam02733
Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.
 65-381 1.30e-147

Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.


Pssm-ID: 460667  Cd Length: 312  Bit Score: 429.56  E-value: 1.30e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878   65 AGLVACNPN-LQLLQGHRVALRSDlDSLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTSPAVGSILAAIRAVA 143
Cdd:pfam02733   1 EGLAAAHPDlLRLVPGPRVVVRAD-APPKGKVALISGGGSGHEPAHAGYVGKGMLDAAVPGEVFASPSPDQILAAIKAVD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  144 QAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAF-TVLKKAGRRGLCGTVLIHKVAGALAEAGVGLEE 222
Cdd:pfam02733  80 GGA--GVLLIVKNYTGDVLNFGMAAELARAEGIKVETVVVGDDVAVgDSGGTVGRRGVAGTVLVHKIAGAAAEAGASLDE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  223 IAKQVNVVAKAMGTLGVSLSSCSVPG-SKPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLMLDHMTNTTnashvP 301
Cdd:pfam02733 158 VARLAEKVNANTRTMGVALSPCTVPGaGKPTFELGEDEMELGMGIHGEPGVKREKLKPADELVEELLDKLLDDD-----P 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  302 VQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVDEPLLKLIDAETTAAA 381
Cdd:pfam02733 233 LLPGDEVAVLVNGLGGTPLLELYIVYRRVLELLEEKGIKVVRSLVGEYMTSLDMAGFSLTLLKLDDELLELLDAPVDTPA 312
PTZ00375 PTZ00375
dihydroxyacetone kinase-like protein; Provisional
 49-572 5.52e-144

dihydroxyacetone kinase-like protein; Provisional


Pssm-ID: 185583 [Multi-domain]  Cd Length: 584  Bit Score: 430.39  E-value: 5.52e-144
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  49 SKKLVNSVAGCADDALAGLVACNPN-LQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVF 127
Cdd:PTZ00375   3 SKKFINSPEKVVSEAVDGLCMTNNDsLKRIENTNVVVRSDID--KTKVLLISGGGSGHEPAHAGFVGKGWLTAAVCGSVF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 128 TSPAVGSILAAIRAVAqaGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLKKAGRRGLCGTVLIH 207
Cdd:PTZ00375  81 ASPSTKHVLAAIEYVP--NGPGCLLIVKNYTGDILNFELAVEQARARGIQVETVLVADDAAFGTKDIANRRGIAGTVLLY 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 208 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGSKPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLM 287
Cdd:PTZ00375 159 KILGAAAEKGASLTQLKKLADRISSNMRSIGVSLSSCSLPGNDPSSTVPPGTMEVGLGIHGEKGLARIPFQGAKDLVKFL 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 288 LDHMTNTTNA----SHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLL 363
Cdd:PTZ00375 239 IGILLGKGKKrgggKTTAIREGAKVALLVNNLGSTTDLEMSILAHHALRQLAQAGLTVVGVHSGRLMTSLEMHGFSLTLL 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 364 LV-DEPLLKLIDAETTAAAWPNVAAVSITGRKRSRVA--PAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNA 440
Cdd:PTZ00375 319 PIeDEDDLQLLDTNQKPLLNFHTPQSSWATAKGPLSAlqLAKPEAEAASRKAATPTNSLLRSVLERVFETLIESENYLNE 398

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 441 LDRAAGDGDCGTTHSRAARAIQEWLKEGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLT----AAAQPLKAKTSLPA 516
Cdd:PTZ00375 399 LDAEVGDGDLGSGLERSSKAVLESLPYLPLEANVRKTLTLISKAVADAFGGSSGPLYGAFLLgganALAEALNGGNAVDA 478

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767967878 517 WSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQEL-----QAWKSPGADLLQVLTKAVKA 572
Cdd:PTZ00375 479 VRAALAAGSHSIQELGGARVGDRTMVDVLIPFAEALnscpsVNEAASSPELLKACSEEARE 539
PRK14481 PRK14481
dihydroxyacetone kinase subunit DhaK; Provisional
 50-382 4.30e-123

dihydroxyacetone kinase subunit DhaK; Provisional


Pssm-ID: 237724  Cd Length: 331  Bit Score: 367.60  E-value: 4.30e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  50 KKLVNSVAGCADDALAGLVACNPNL-QLLQGHRVALRSDLDSlkGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFT 128
Cdd:PRK14481   2 KKLINDPETVVDEMLEGLVAAHPDLvTRIDDTDVIVRKDKPP--GKVALVSGGGSGHEPAHAGFVGEGMLDAAVCGAVFT 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 129 SPAVGSILAAIRAVAQAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFT-VLKKAGRRGLCGTVLIH 207
Cdd:PRK14481  80 SPTPDQILEAIKAVDTGA--GVLLIVKNYSGDVMNFEMAAELAEMEGIEVASVVVDDDVAVEdSLYTQGRRGVAGTVFVH 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 208 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGS-KPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKL 286
Cdd:PRK14481 158 KIAGAAAEAGASLDEVKALAEKVNPNIRSMGVALSPCTVPAVgKPGFDLGDDEIEIGIGIHGEPGRRREKLKPADEIAEE 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 287 MLDHMTNTtnashVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVD 366
Cdd:PRK14481 238 LLEKILED-----LKLVAGDEVLVLVNGMGATPLMELYIVYNDVAELLEERGVTVARSLVGNYMTSLDMAGFSITLLKLD 312

                        330
                 ....*....|....*.
gi 767967878 367 EPLLKLIDAETTAAAW 382
Cdd:PRK14481 313 DELLELLDAPVDTPAL 328
dhaK1 TIGR02363
dihydroxyacetone kinase, DhaK subunit; Two types of dihydroxyacetone kinase (glycerone kinase) ...
 50-382 3.09e-117

dihydroxyacetone kinase, DhaK subunit; Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the DhaK subunit of the latter type of dihydroxyacetone kinase, but it specifically excludes the DhaK paralog DhaK2 (TIGR02362) found in the same operon as DhaK and DhaK in the Firmicutes.


Pssm-ID: 274098  Cd Length: 329  Bit Score: 352.43  E-value: 3.09e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878   50 KKLVNSVAGCADDALAGLVACNPNL-QLLQGHRVALRSDLDSlKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFT 128
Cdd:TIGR02363   2 KKLINDPEDVVAEMLDGLVKAHPELvTLVADTRVIVRKDKKV-NGKVALVSGGGSGHEPAHAGFVGYGMLDAAVPGEVFT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  129 SPAVGSILAAIRAVAQAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFT-VLKKAGRRGLCGTVLIH 207
Cdd:TIGR02363  81 SPTPDQILEAIKAVDQGA--GVLLIVKNYTGDVMNFEMAAELAEDEGIKVATVVVDDDIAVEdSLYTAGRRGVAGTVFVH 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  208 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGS-KPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKL 286
Cdd:TIGR02363 159 KIAGAAAEKGASLDELKSLGEKVNPNTKSIGVALTACTVPAVgKPGFDLADDEMEIGVGIHGEPGIRREKMKSSDEIADE 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  287 MLDHMtnttnASHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLLLVD 366
Cdd:TIGR02363 239 LLDKL-----LDDLGLQSGDRVIVLVNGMGATPLMELYIFYNDVQRLLEQRGVNVARTLVGNYMTSLDMAGFSLTLLKLD 313

                         330
                  ....*....|....*.
gi 767967878  367 EPLLKLIDAETTAAAW 382
Cdd:TIGR02363 314 DELLELWDAPVTTIAL 329
PRK11468 PRK11468
dihydroxyacetone kinase subunit DhaK; Provisional
 50-382 3.30e-96

dihydroxyacetone kinase subunit DhaK; Provisional


Pssm-ID: 183150  Cd Length: 356  Bit Score: 299.24  E-value: 3.30e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  50 KKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDsLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 129
Cdd:PRK11468   2 KKLINDVEDVLDEQLAGLAKAHPELTLHQDPVYVTRADAP-VAGKVALLSGGGSGHEPMHCGFVGQGMLDGACPGEIFTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 130 PAVGSILAAIRAVaqAGTVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFT-VLKKAGRRGLCGTVLIHK 208
Cdd:PRK11468  81 PTPDQMFECAMQV--DGGEGVLLIIKNYTGDVLNFETATELLHDSGVKVTTVLIDDDVAVKdSLYTAGRRGVANTVLIEK 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 209 VAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPGS-KPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLM 287
Cdd:PRK11468 159 LVGAAAERGYSLDQCAELGRKLNNQGHSIGIALGACTVPAAgKPSFTLADNEMEFGVGIHGEPGIDRRPFSSLDQTVDEM 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 288 LDHMTNTTNASHV-------------------PVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGT 348
Cdd:PRK11468 239 FDTLLENGSYHRTlrfwdrqqgswqeeeqtkqPLQSGDRVIALVNNLGATPLSELYGVYNRLATRCEQAGLTIERNLIGA 318

                        330       340       350
                 ....*....|....*....|....*....|....
gi 767967878 349 FMSALEMPGISLTLLLVDEPLLKLIDAETTAAAW 382
Cdd:PRK11468 319 YCTSLDMQGFSITLLKVDDETLALWDAPVHTPAL 352
PRK14483 PRK14483
DhaKLM operon coactivator DhaQ; Provisional
 50-382 9.91e-80

DhaKLM operon coactivator DhaQ; Provisional


Pssm-ID: 172956  Cd Length: 329  Bit Score: 255.36  E-value: 9.91e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  50 KKLVNSVAGCADDALAGLVACNPNLQllQGHRVALRSDLDSLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTS 129
Cdd:PRK14483   2 KKIMNDVQNIVQDMLHGFYFAHPNLD--ETNNIPYVYDIEKDDQLVPIISGGGSGHEPAHIGYVGKGMLTAAVNGSIFTP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 130 PAVGSILAAIRAVAQAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLK--KAGRRGLCGTVLIH 207
Cdd:PRK14483  80 PTAEQILAATRLVPKGK--GVFFIIKNFEADVAEFSAAIQIARQEGRQIKYIIVHDDISVEDDAsfNKRRRGVAGTVLLH 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 208 KVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPG-SKPTFELSADEVELGLGIHGEAGVRRIKMAT----ADE 282
Cdd:PRK14483 158 KILGAAALEGASLDELEQLGLSLTENIATLGVALSPANLPVaGLPSFDLNEDEISYGIGIHGEPGYRKEPFSSseilAIE 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 283 IV-KLmldhmtnttnASHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLT 361
Cdd:PRK14483 238 LVnKL----------KSKYRWQKGDNFILLINGLGATTLMEQYIFANDIRRLLELEGLQITFVKVGTLLTSLDMKGISLT 307

                        330       340
                 ....*....|....*....|..
gi 767967878 362 LLLV-DEPLLKLIDAETTAAAW 382
Cdd:PRK14483 308 LLKVkDPDWLDWLKAPTRAAAW 329
dhaK1b TIGR02362
probable dihydroxyacetone kinase DhaK1b subunit; Two types of dihydroxyacetone kinase ...
 51-382 3.00e-68

probable dihydroxyacetone kinase DhaK1b subunit; Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form with a phosphoprotein donor related to PTS transport proteins. This family represents a protein, unique to the Firmicutes (low GC Gram-positives), that appears to be a divergent second copy of the K subunit of that complex; its gene is always found in operons with the other three proteins of the complex.


Pssm-ID: 213706  Cd Length: 326  Bit Score: 225.45  E-value: 3.00e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878   51 KLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDslKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTSP 130
Cdd:TIGR02362   1 KIINEPQNAVSQAIQGIQWAYPNLVQVPDLPGIYDSNFD--DQQIPIISGGGSGHEPAHWGYVGEGMLSAAIMGDVFVPP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  131 AVGSILAAIRAVAQAGtvGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDD-SAFTVLKKAGRRGLCGTVLIHKV 209
Cdd:TIGR02362  79 TAQDILEAIRQVDRGK--GVFVIIKNFEADLSEFSQAIQQARQEGRQIKYIIVHDDiSVEHESFKQRRRGVAGTILVHKI 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  210 AGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSVPG-SKPTFELSADEVELGLGIHGEAGVRRIKMAT----ADEIV 284
Cdd:TIGR02362 157 LGAAAAEGASLDELEHIAAALVTNIATIGVAAKSARIPGqSTPSFDLEEGEIYYGIGIHGEPGYRTEPFVSsehlAVELV 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  285 -KLMLDHMTnttnashvpvQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALVGTFMSALEMPGISLTLL 363
Cdd:TIGR02362 237 nKLKLKFRW----------QADDHYAVLVNNLGGTTPMEQMVFNNDVHELLALEALHLPFIKVGTFLTSLDMHGLSLTLL 306

                         330       340
                  ....*....|....*....|
gi 767967878  364 -LVDEPLLKLIDAETTAAAW 382
Cdd:TIGR02362 307 rLKDPQWLDYLNAPVDAAAW 326
Dak2 pfam02734
DAK2 domain; This domain is the predicted phosphatase domain of the dihydroxyacetone kinase ...
 444-572 4.05e-33

DAK2 domain; This domain is the predicted phosphatase domain of the dihydroxyacetone kinase family.


Pssm-ID: 460668 [Multi-domain]  Cd Length: 175  Bit Score: 124.99  E-value: 4.05e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  444 AAGDGDCGTTHSRAARAIQEWLKEGPPpASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKAKTSL--PAWSAAM 521
Cdd:pfam02734   1 PVGDGDHGTNMARGFEAALKALEDLEP-ASLAEVLKALAMALLSGAGGNSGPLYGQFFRGAAKALKGKEELdaEDLAAAL 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767967878  522 DAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKA 572
Cdd:pfam02734  80 EAALEAIQARGKARPGDKTMLDVLRPAAEALEAAAEAGEDLAEALEAAVKA 130
DAK1 COG2376
Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is ...
 424-572 4.95e-19

Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441943 [Multi-domain]  Cd Length: 206  Bit Score: 85.64  E-value: 4.95e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 424 LERVCSTLLGLEEHLNALDRAAGDGDCGTTHSRAARAIQEwlKEGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTA 503
Cdd:COG2376    1 MKAVADVIAENRKFLNDLDAVVGDGDHGINMARGFDAVRA--ALDAAPADPGVVLRAAGMKVASVVGGGSGGLVGTGFLD 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767967878 504 AAQPLKAKTSLPA--WSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKA 572
Cdd:COG2376   79 AAVALKGETSPTAdqVAAALRAADEGIQGRGVAYTGDKTNFDAAAPAAEAIEEAVAAGTAAAAALDEAAAA 149
dha_L_ycgS TIGR02365
dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Two types of dihydroxyacetone ...
 424-572 5.98e-17

dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the subunit homologous to the E. coli YcgS subunit.


Pssm-ID: 274099 [Multi-domain]  Cd Length: 194  Bit Score: 79.32  E-value: 5.98e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  424 LERVCSTLLGLEEHLNALDRAAGDGDCGTTHSRAARAIQEWLKEgPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTA 503
Cdd:TIGR02365   5 LKNCGDLIIENKEYLTELDRAIGDGDHGINMARGFSEVKEKLDA-FKDKTIGEILKNTGMTLISKVGGASGPLYGTAFLK 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767967878  504 AAQPLKAKTSLPAWSAA--MDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKA 572
Cdd:TIGR02365  84 ASKALKDDEILDAEDLAeiLQAGLEGIQSRGKATPGEKTMVDVWAPVVEALRKAADEPDALAAAREAAEQG 154
DAK1 COG2376
Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is ...
 50-248 4.42e-14

Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441943 [Multi-domain]  Cd Length: 206  Bit Score: 71.38  E-value: 4.42e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878  50 KKLVNSVAGCADDALAGLVACNPN---LQLLQGHRVALRSDLDSLKGRVALLSGGGSGhepahaGFIGKGMLTGVIAGAV 126
Cdd:COG2376   12 RKFLNDLDAVVGDGDHGINMARGFdavRAALDAAPADPGVVLRAAGMKVASVVGGGSG------GLVGTGFLDAAVALKG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 127 FTSPAVGSILAAIRAVAQA-GTVGtllivKNYTGDRLNFGLAREQARAegIPvEMVVIGDDsaftvlkkagrrglcgtvl 205
Cdd:COG2376   86 ETSPTADQVAAALRAADEGiQGRG-----VAYTGDKTNFDAAAPAAEA--IE-EAVAAGTA------------------- 138

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 767967878 206 ihkVAGALAEAgvglEEIAKQvnvVAKAMGTLGVSLSSCSVPG 248
Cdd:COG2376  139 ---AAAALDEA----AAAAEK---GAEATRSMGAALGRATYPG 171
PRK10005 PRK10005
dihydroxyacetone kinase ADP-binding subunit DhaL;
424-572 1.39e-10

dihydroxyacetone kinase ADP-binding subunit DhaL;


Pssm-ID: 182192 [Multi-domain]  Cd Length: 210  Bit Score: 61.29  E-value: 1.39e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767967878 424 LERVCSTLLGLEEHLNALDRAAGDGDCGTTHSRAARAIQEWLkegPPPASP--AQLLSKLSVLLLEKMGGSSGALYGLFL 501
Cdd:PRK10005  12 LTRCGDIFTEESDYLTGLDREIGDADHGLNMNRGFSKVVEKL---PAIADKdiGFILKNTGMTLLSSVGGASGPLYGTFF 88

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767967878 502 TAAAQPLKAKTSLPA--WSAAMDAGLEAMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKA 572
Cdd:PRK10005  89 IRAAQATQARQSLTLeeLYQMFRDGADGVISRGKAEPGDKTMCDVWVPVVESLRQSSEQNLSVPAALNAAVSI 161
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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