|
Name |
Accession |
Description |
Interval |
E-value |
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
6-277 |
5.25e-41 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 149.33 E-value: 5.25e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 6 ALQAARQGELDVLRSLHAAGLLGPSLRDPLDALPVHHAARAGKLHCLRFLVEEAALPAAARARNGATPAHDASATGHLAC 85
Cdd:COG0666 23 LLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEI 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 86 LQWLLSQGGcRVQDKDNSGATVLHLAARFGHPEVVNWLLHHgGGDPTAATDMGALPIHYAAAKGDFPSLRLLVEHYPEgV 165
Cdd:COG0666 103 VKLLLEAGA-DVNARDKDGETPLHLAAYNGNLEIVKLLLEA-GADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGAD-V 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 166 NAQTKNGATPLYLACQEGHLEVTQYLVqECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVScTDVSLSEQDKDGATAMH 245
Cdd:COG0666 180 NARDNDGETPLHLAAENGHLEIVKLLL-EAGADVNAKDNDGKTALDLAAENGNLEIVKLLLE-AGADLNAKDKDGLTALL 257
|
250 260 270
....*....|....*....|....*....|..
gi 767906257 246 FAASRGHTKVLSWLLLHGGEISADLWGGTPLH 277
Cdd:COG0666 258 LAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
33-309 |
8.15e-41 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 148.95 E-value: 8.15e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 33 DPLDALPVHHAARAGKLHCLRFLVEEAALPAAARARNGATPAHDASATGHLACLQWLLSQGGCRVQDKDNSGATVLHLAA 112
Cdd:COG0666 16 LLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 113 RFGHPEVVNWLLHHgGGDPTAATDMGALPIHYAAAKGDFPSLRLLVEHypeG--VNAQTKNGATPLYLACQEGHLEVTQY 190
Cdd:COG0666 96 RNGDLEIVKLLLEA-GADVNARDKDGETPLHLAAYNGNLEIVKLLLEA---GadVNAQDNDGNTPLHLAAANGNLEIVKL 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 191 LVqECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVScTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGGEISA-D 269
Cdd:COG0666 172 LL-EAGADVNARDNDGETPLHLAAENGHLEIVKLLLE-AGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAkD 249
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 767906257 270 LWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYTAA 309
Cdd:COG0666 250 KDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
52-324 |
1.67e-40 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 148.18 E-value: 1.67e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 52 LRFLVEEAALPAAARARNGATPAHDASATGHLACLQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGGGDP 131
Cdd:COG0666 1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 132 TAATDMGALPIHYAAAKGDFPSLRLLVEHYPEgVNAQTKNGATPLYLACQEGHLEVTQYLVqECGADPHARAHDGMTPLH 211
Cdd:COG0666 81 NAKDDGGNTLLHAAARNGDLEIVKLLLEAGAD-VNARDKDGETPLHLAAYNGNLEIVKLLL-EAGADVNAQDNDGNTPLH 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 212 AAAQMGHSPVIVWLVSCtDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGGEISA-DLWGGTPLHDAAENGELECCQI 290
Cdd:COG0666 159 LAAANGNLEIVKLLLEA-GADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAkDNDGKTALDLAAENGNLEIVKL 237
|
250 260 270
....*....|....*....|....*....|....
gi 767906257 291 LVVNGAELDVRDRDGYTAADLSDFNGHSHCTRYL 324
Cdd:COG0666 238 LLEAGADLNAKDKDGLTALLLAAAAGAALIVKLL 271
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
99-325 |
3.05e-36 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 136.24 E-value: 3.05e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 99 DKDNSGATVLHLAARFGHPEVVNWLLHHGGGDPTAATDMGALPIHYAAAKGDFPSLRLLVEHYPEGVNAQTKNGATPLYL 178
Cdd:COG0666 14 ALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 179 ACQEGHLEVTQYLVqECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVSCtDVSLSEQDKDGATAMHFAASRGHTKVLSW 258
Cdd:COG0666 94 AARNGDLEIVKLLL-EAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEA-GADVNAQDNDGNTPLHLAAANGNLEIVKL 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767906257 259 LLLHGGEISA-DLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYTAADLSDFNGHSHCTRYLR 325
Cdd:COG0666 172 LLEAGADVNArDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLL 239
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
210-302 |
2.78e-19 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 82.47 E-value: 2.78e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 210 LHAAAQMGHSPVIVWLVSCtDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGgEISADLWGGTPLHDAAENGELECCQ 289
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLEN-GADANLQDKNGRTALHLAAKNGHLEIVKLLLEHA-DVNLKDNGRTALHYAARSGHLEIVK 78
|
90
....*....|...
gi 767906257 290 ILVVNGAELDVRD 302
Cdd:pfam12796 79 LLLEKGADINVKD 91
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
176-268 |
3.07e-18 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 79.77 E-value: 3.07e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 176 LYLACQEGHLEVTQYLVqECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVSCTDVSLSEqdkDGATAMHFAASRGHTKV 255
Cdd:pfam12796 1 LHLAAKNGNLELVKLLL-ENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVNLKD---NGRTALHYAARSGHLEI 76
|
90
....*....|...
gi 767906257 256 LSWLLLHGGEISA 268
Cdd:pfam12796 77 VKLLLEKGADINV 89
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
108-202 |
9.80e-18 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 78.23 E-value: 9.80e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 108 LHLAARFGHPEVVNWLLHHgGGDPTAATDMGALPIHYAAAKGDFPSLRLLVEHypEGVNAQTkNGATPLYLACQEGHLEV 187
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLEN-GADANLQDKNGRTALHLAAKNGHLEIVKLLLEH--ADVNLKD-NGRTALHYAARSGHLEI 76
|
90
....*....|....*
gi 767906257 188 TQYLVqECGADPHAR 202
Cdd:pfam12796 77 VKLLL-EKGADINVK 90
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
142-228 |
1.07e-16 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 75.15 E-value: 1.07e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 142 IHYAAAKGDFPSLRLLVEHyPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADphaRAHDGMTPLHAAAQMGHSPV 221
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLEN-GADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVN---LKDNGRTALHYAARSGHLEI 76
|
....*..
gi 767906257 222 IVWLVSC 228
Cdd:pfam12796 77 VKLLLEK 83
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
41-127 |
8.57e-15 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 69.76 E-value: 8.57e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 41 HHAARAGKLHCLRFLVEEAALPAAARArNGATPAHDASATGHLACLQWLLSQGgcrVQDKDNSGATVLHLAARFGHPEVV 120
Cdd:pfam12796 2 HLAAKNGNLELVKLLLENGADANLQDK-NGRTALHLAAKNGHLEIVKLLLEHA---DVNLKDNGRTALHYAARSGHLEIV 77
|
....*..
gi 767906257 121 NWLLHHG 127
Cdd:pfam12796 78 KLLLEKG 84
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
89-325 |
2.73e-14 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 75.06 E-value: 2.73e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 89 LLSQGGcRVQDKDNSGATVLHLAARFGHP---EVVNWLLHhGGGDPTAATDMGALPIH-YAAAKGDFPSLRLLVEHypeG 164
Cdd:PHA03095 33 LLAAGA-DVNFRGEYGKTPLHLYLHYSSEkvkDIVRLLLE-AGADVNAPERCGFTPLHlYLYNATTLDVIKLLIKA---G 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 165 --VNAQTKNGATPL--YLACQEGHLEVTQYLVQEcGADPHARAHDGMTPLHAaaqmghspvivwLVSCTDVSL------- 233
Cdd:PHA03095 108 adVNAKDKVGRTPLhvYLSGFNINPKVIRLLLRK-GADVNALDLYGMTPLAV------------LLKSRNANVellrlli 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 234 ------SEQDKDGATAMH-FAAS-RGHTKVLSWLLLHGGEISA-DLWGGTPLHDAAENGelECCQILVVN----GAELDV 300
Cdd:PHA03095 175 dagadvYAVDDRFRSLLHhHLQSfKPRARIVRELIRAGCDPAAtDMLGNTPLHSMATGS--SCKRSLVLPlliaGISINA 252
|
250 260
....*....|....*....|....*.
gi 767906257 301 RDRDGYTAADL-SDFNGHSHCTRYLR 325
Cdd:PHA03095 253 RNRYGQTPLHYaAVFNNPRACRRLIA 278
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
75-163 |
1.43e-13 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 66.29 E-value: 1.43e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 75 HDASATGHLACLQWLLsQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGGGDptaATDMGALPIHYAAAKGDFPSL 154
Cdd:pfam12796 2 HLAAKNGNLELVKLLL-ENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVN---LKDNGRTALHYAARSGHLEIV 77
|
....*....
gi 767906257 155 RLLVEHYPE 163
Cdd:pfam12796 78 KLLLEKGAD 86
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
89-345 |
1.99e-13 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 72.36 E-value: 1.99e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 89 LLSQGGCRVQDKDNSGATVLHLAARFGH-PEVVNWLLHHGGgDPTAATDMGALPIH-YAAAKG-DFPSLRLLVEHypeG- 164
Cdd:PHA03095 68 LLLEAGADVNAPERCGFTPLHLYLYNATtLDVIKLLIKAGA-DVNAKDKVGRTPLHvYLSGFNiNPKVIRLLLRK---Ga 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 165 -VNAQTKNGATPL--YLACQEGHLEVTQYLVqECGADPHARAHDGMTPLHAAAQMGH-SPVIVWLVSCTDVSLSEQDKDG 240
Cdd:PHA03095 144 dVNALDLYGMTPLavLLKSRNANVELLRLLI-DAGADVYAVDDRFRSLLHHHLQSFKpRARIVRELIRAGCDPAATDMLG 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 241 ATAMHFAASRGHTK--VLSWLLLHGGEISA-DLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYTAADLSDFNGH 317
Cdd:PHA03095 223 NTPLHSMATGSSCKrsLVLPLLIAGISINArNRYGQTPLHYAAVFNNPRACRRLIALGADINAVSSDGNTPLSLMVRNNN 302
|
250 260
....*....|....*....|....*...
gi 767906257 318 SHCTRylrtvenlsvehRVLSRDPSAEL 345
Cdd:PHA03095 303 GRAVR------------AALAKNPSAET 318
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
94-267 |
3.91e-13 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 71.15 E-value: 3.91e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 94 GCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHgGGDPTAATDMGALPIHYAAAKGDFPSLRLLVEH--YpegVNAQTKN 171
Cdd:PHA02874 114 GIDVNIKDAELKTFLHYAIKKGDLESIKMLFEY-GADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKgaY---ANVKDNN 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 172 GATPLYLACQEGHLEVTQYLVQEcGADPHARAHDGMTPLHAAAQMGHSpVIVWLVSctDVSLSEQDKDGATAMHFAASRG 251
Cdd:PHA02874 190 GESPLHNAAEYGDYACIKLLIDH-GNHIMNKCKNGFTPLHNAIIHNRS-AIELLIN--NASINDQDIDGSTPLHHAINPP 265
|
170
....*....|....*..
gi 767906257 252 HTK-VLSWLLLHGGEIS 267
Cdd:PHA02874 266 CDIdIIDILLYHKADIS 282
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
70-223 |
4.50e-13 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 71.82 E-value: 4.50e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 70 GATPAHDASATGHLACLQWLLSQGgCRVQDKDNSGATVLHLAARFGHPEVVnWLLHH--GGGDPTAATDMGALpihyAAA 147
Cdd:PLN03192 558 GRTPLHIAASKGYEDCVLVLLKHA-CNVHIRDANGNTALWNAISAKHHKIF-RILYHfaSISDPHAAGDLLCT----AAK 631
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 148 KGDFPSLRLLVEHypeGVNAQTKN--GATPLYLACQEGHLEVTQYLVQEcGAD-PHARAHDGMTP-----LHAAAQMGHS 219
Cdd:PLN03192 632 RNDLTAMKELLKQ---GLNVDSEDhqGATALQVAMAEDHVDMVRLLIMN-GADvDKANTDDDFSPtelreLLQKRELGHS 707
|
....
gi 767906257 220 PVIV 223
Cdd:PLN03192 708 ITIV 711
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
88-230 |
2.62e-11 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 65.46 E-value: 2.62e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 88 WLLSQGGCRVQDKDNSGATVLHLAA--RFGHPEVVNWLLHHGGgDPTAATDMGALPIHYAAA--KGDFPSLRLLVEH--- 160
Cdd:PHA03100 90 KLLLEYGANVNAPDNNGITPLLYAIskKSNSYSIVEYLLDNGA-NVNIKNSDGENLLHLYLEsnKIDLKILKLLIDKgvd 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 161 ------------YPEGVNAQTKNGATPLYLACQEGHLEVTQYLVqECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVSC 228
Cdd:PHA03100 169 inaknrvnyllsYGVPINIKDVYGFTPLHYAVYNNNPEFVKYLL-DLGANPNLVNKYGDTPLHIAILNNNKEIFKLLLNN 247
|
..
gi 767906257 229 TD 230
Cdd:PHA03100 248 GP 249
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
206-260 |
8.77e-11 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 57.28 E-value: 8.77e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 767906257 206 GMTPLHAAAQMGHSPVIVWLVsCTDVSLSEQDKDGATAMHFAASRGHTKVLSWLL 260
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLL-EKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
196-365 |
9.86e-11 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 64.50 E-value: 9.86e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 196 GADPHARAHDGMTPLHAAAQMGHSP-VIVWLVSCTDVSLseQDKDGATAMHFAASRGHTKVLsWLLLHGGEISADLWGGT 274
Cdd:PLN03192 548 KLDPDIGDSKGRTPLHIAASKGYEDcVLVLLKHACNVHI--RDANGNTALWNAISAKHHKIF-RILYHFASISDPHAAGD 624
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 275 PLHDAAENGELECCQILVVNGAELDVRDRDGYTAADLSDFNGHSHCTRYLrTVENLSVEHRVLSRDPSAE-----LEAKQ 349
Cdd:PLN03192 625 LLCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLL-IMNGADVDKANTDDDFSPTelrelLQKRE 703
|
170
....*....|....*.
gi 767906257 350 PDSGMSSPNTTVSVQP 365
Cdd:PLN03192 704 LGHSITIVDSVPADEP 719
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
8-101 |
1.80e-10 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 57.43 E-value: 1.80e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 8 QAARQGELDVLRSLHAAGLlGPSLRDPLDALPVHHAARAGKLHCLRFLVEEaalPAAARARNGATPAHDASATGHLACLQ 87
Cdd:pfam12796 3 LAAKNGNLELVKLLLENGA-DANLQDKNGRTALHLAAKNGHLEIVKLLLEH---ADVNLKDNGRTALHYAARSGHLEIVK 78
|
90
....*....|....
gi 767906257 88 WLLSQgGCRVQDKD 101
Cdd:pfam12796 79 LLLEK-GADINVKD 91
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
48-307 |
2.03e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 62.67 E-value: 2.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 48 KLHCLRFLVEEAalpaaararngATPAHDASATGHLACLQWLLsqggcrvqdkdNSGATVLHLAARFGHP---------- 117
Cdd:PHA02874 24 KGNCINISVDET-----------TTPLIDAIRSGDAKIVELFI-----------KHGADINHINTKIPHPlltaikigah 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 118 EVVNWLLHHGggdptaaTDMGALPIhyaaakgdfPSLR--LLVEHYPEGVNAQTKNG--ATPLYLACQEGHLEVTQYLVq 193
Cdd:PHA02874 82 DIIKLLIDNG-------VDTSILPI---------PCIEkdMIKTILDCGIDVNIKDAelKTFLHYAIKKGDLESIKMLF- 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 194 ECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVScTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGGEISADLWGG 273
Cdd:PHA02874 145 EYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLE-KGAYANVKDNNGESPLHNAAEYGDYACIKLLIDHGNHIMNKCKNG 223
|
250 260 270
....*....|....*....|....*....|....*..
gi 767906257 274 -TPLHDAA--ENGELEccqiLVVNGAELDVRDRDGYT 307
Cdd:PHA02874 224 fTPLHNAIihNRSAIE----LLINNASINDQDIDGST 256
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
76-309 |
1.36e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 60.00 E-value: 1.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 76 DASATGHLACLQWLLSQG---GCRVQDkdnsGATVLHLAARFGHPEVVNWLLHHGGGDPTAATDMGAlPIHYAAAKGDFP 152
Cdd:PHA02875 8 DAILFGELDIARRLLDIGinpNFEIYD----GISPIKLAMKFRDSEAIKLLMKHGAIPDVKYPDIES-ELHDAVEEGDVK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 153 SLRLLVEHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQEcGADPHARAHDGMTPLHAAAQMGHSPVIVWLV---SCT 229
Cdd:PHA02875 83 AVEELLDLGKFADDVFYKDGMTPLHLATILKKLDIMKLLIAR-GADPDIPNTDKFSPLHLAVMMGDIKGIELLIdhkACL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 230 DVSlseqdkdgatamhfaasrghtkvlswlllhggeisaDLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYTAA 309
Cdd:PHA02875 162 DIE------------------------------------DCCGCTPLIIAMAKGDIAICKMLLDSGANIDYFGKNGCVAA 205
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
174-226 |
2.44e-09 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 53.05 E-value: 2.44e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 767906257 174 TPLYLACQEGHLEVTQYLVQEcGADPHARAHDGMTPLHAAAQMGHSPVIVWLV 226
Cdd:pfam13637 3 TALHAAAASGHLELLRLLLEK-GADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
123-304 |
4.21e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 59.31 E-value: 4.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 123 LLHHGGGDPTAATDMGALPIHYAAAKgdfPSLRLLVEHYPE---GVNAQTKNGATPLYLACQEGH-LEVTQYLVQEcGAD 198
Cdd:PHA02876 258 LLYDAGFSVNSIDDCKNTPLHHASQA---PSLSRLVPKLLErgaDVNAKNIKGETPLYLMAKNGYdTENIRTLIML-GAD 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 199 PHARAHDGMTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGGEISA-DLWGGTPLH 277
Cdd:PHA02876 334 VNAADRLYITPLHQASTLDRNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEAlSQKIGTALH 413
|
170 180
....*....|....*....|....*...
gi 767906257 278 DA-AENGELECCQILVVNGAELDVRDRD 304
Cdd:PHA02876 414 FAlCGTNPYMSVKTLIDRGANVNSKNKD 441
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
141-192 |
7.31e-09 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 51.89 E-value: 7.31e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 767906257 141 PIHYAAAKGDFPSLRLLVEHYPEgVNAQTKNGATPLYLACQEGHLEVTQYLV 192
Cdd:pfam13637 4 ALHAAAASGHLELLRLLLEKGAD-INAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
72-124 |
9.52e-09 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 51.51 E-value: 9.52e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 767906257 72 TPAHDASATGHLACLQWLLSQGgCRVQDKDNSGATVLHLAARFGHPEVVNWLL 124
Cdd:pfam13637 3 TALHAAAASGHLELLRLLLEKG-ADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
130-229 |
1.07e-07 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 54.52 E-value: 1.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 130 DPTAAtDMGALPIHYAAAKGDFPSLRLLVEHYPEgVNAQTKNGATPLYLACQEGHLEVTQYLVqECGADPHARAHDGMTP 209
Cdd:PTZ00322 75 DPVVA-HMLTVELCQLAASGDAVGARILLTGGAD-PNCRDYDGRTPLHIACANGHVQVVRVLL-EFGADPTLLDKDGKTP 151
|
90 100
....*....|....*....|
gi 767906257 210 LHAAAQMGHSPVIVWLVSCT 229
Cdd:PTZ00322 152 LELAEENGFREVVQLLSRHS 171
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
89-145 |
1.61e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 48.11 E-value: 1.61e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 767906257 89 LLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHgGGDPTAATDMGALPIHYA 145
Cdd:pfam13857 1 LLEHGPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAY-GVDLNLKDEEGLTALDLA 56
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
242-292 |
4.80e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 46.50 E-value: 4.80e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 767906257 242 TAMHFAASRGHTKVLSWLLLHGGEISA-DLWGGTPLHDAAENGELECCQILV 292
Cdd:pfam13637 3 TALHAAAASGHLELLRLLLEKGADINAvDGNGETALHFAASNGNVEVLKLLL 54
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
276-324 |
7.26e-07 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 47.42 E-value: 7.26e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 767906257 276 LHDAAENGELECCQILVVNGAELDVRDRDGYTAADLSDFNGHSHCTRYL 324
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLL 49
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
272-324 |
7.60e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 46.11 E-value: 7.60e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 767906257 272 GGTPLHDAAENGELECCQILVVNGAELDVRDRDGYTAADLSDFNGHSHCTRYL 324
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLL 53
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
106-158 |
9.34e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 45.73 E-value: 9.34e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 767906257 106 TVLHLAARFGHPEVVNWLLHHgGGDPTAATDMGALPIHYAAAKGDFPSLRLLV 158
Cdd:pfam13637 3 TALHAAAASGHLELLRLLLEK-GADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
191-267 |
2.62e-06 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 50.28 E-value: 2.62e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767906257 191 LVQECGADPHARAHDGMTPLHAAAQMGHSPVI-VWLVSCTDVSLSeqDKDGATAMHFAASRGHTKVLSWLLLHGGEIS 267
Cdd:PTZ00322 100 ILLTGGADPNCRDYDGRTPLHIACANGHVQVVrVLLEFGADPTLL--DKDGKTPLELAEENGFREVVQLLSRHSQCHF 175
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
269-311 |
3.12e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 44.26 E-value: 3.12e-06
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 767906257 269 DLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYTAADL 311
Cdd:pfam13857 13 DGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDL 55
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
75-247 |
4.43e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 49.19 E-value: 4.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 75 HDASATGHLACLQWLLSQGGcRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGGGdPTAATDMGALPIHYAAAKGDFPSL 154
Cdd:PHA02874 129 HYAIKKGDLESIKMLFEYGA-DVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAY-ANVKDNNGESPLHNAAEYGDYACI 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 155 RLLVEHyPEGVNAQTKNGATPLYLACQEGHlEVTQYLVQEcgADPHARAHDGMTPLHAAAQMGHSPVIVWLVSCTDVSLS 234
Cdd:PHA02874 207 KLLIDH-GNHIMNKCKNGFTPLHNAIIHNR-SAIELLINN--ASINDQDIDGSTPLHHAINPPCDIDIIDILLYHKADIS 282
|
170
....*....|...
gi 767906257 235 EQDKDGATAMHFA 247
Cdd:PHA02874 283 IKDNKGENPIDTA 295
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
72-298 |
4.96e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 49.29 E-value: 4.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 72 TPAHDASATGHLACLQWLLSQGGCRVQDKDNSGATVLHLAARFGH-PEVVNWLLHHgGGDPTAATDMGALPIHYAAAKGD 150
Cdd:PHA02876 275 TPLHHASQAPSLSRLVPKLLERGADVNAKNIKGETPLYLMAKNGYdTENIRTLIML-GADVNAADRLYITPLHQASTLDR 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 151 FPSLRLLVEHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVqECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVSCTD 230
Cdd:PHA02876 354 NKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLL-DYGADIEALSQKIGTALHFALCGTNPYMSVKTLIDRG 432
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 231 VSLSEQDKDGATAMHFAASRG-HTKVLSWLLLHGGEISA-DLWGGTPLHDAAENGELecCQILVVNGAEL 298
Cdd:PHA02876 433 ANVNSKNKDLSTPLHYACKKNcKLDVIEMLLDNGADVNAiNIQNQYPLLIALEYHGI--VNILLHYGAEL 500
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
72-211 |
5.68e-06 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 48.86 E-value: 5.68e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 72 TPAHDASATGHLACLQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHhggGDPT-----AATDM--GALPIHY 144
Cdd:cd22192 19 SPLLLAAKENDVQAIKKLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLME---AAPElvnepMTSDLyqGETALHI 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 145 AAAKGDFPSLRLLVEHYPEGVNAQT---------KN----GATPL-YLACQeGHLEVTQYLVQEcGADPHARAHDGMTPL 210
Cdd:cd22192 96 AVVNQNLNLVRELIARGADVVSPRAtgtffrpgpKNliyyGEHPLsFAACV-GNEEIVRLLIEH-GADIRAQDSLGNTVL 173
|
.
gi 767906257 211 H 211
Cdd:cd22192 174 H 174
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
118-294 |
6.16e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 48.72 E-value: 6.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 118 EVVNWLLHHGGGDPTAATDMGALPIHYAAAKGDFPSLRLLVEhYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQEcGA 197
Cdd:PHA02878 148 EITKLLLSYGADINMKDRHKGNTALHYATENKDQRLTELLLS-YGANVNIPDKTNNSPLHHAVKHYNKPIVHILLEN-GA 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 198 DPHARAHDGMTPLHAAAQ--MGHSPVIVWLVSCTDVSLSEQDKdGATAMHFAASrgHTKVLSWLLLHGGEISA-DLWGGT 274
Cdd:PHA02878 226 STDARDKCGNTPLHISVGycKDYDILKLLLEHGVDVNAKSYIL-GLTALHSSIK--SERKLKLLLEYGADINSlNSYKLT 302
|
170 180
....*....|....*....|.
gi 767906257 275 PLHDAAEN-GELECCQILVVN 294
Cdd:PHA02878 303 PLSSAVKQyLCINIGRILISN 323
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
72-225 |
8.65e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 48.06 E-value: 8.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 72 TPAHDASATGHLACLQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGGGDPTAATDMGAlPIHYAAAKGDF 151
Cdd:PHA02875 70 SELHDAVEEGDVKAVEELLDLGKFADDVFYKDGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFS-PLHLAVMMGDI 148
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767906257 152 PSLRLLVEHyPEGVNAQTKNGATPLYLACQEGHLEVTQYLVqECGADPHARAHDGMTPLHAAAQMGHSPVIVWL 225
Cdd:PHA02875 149 KGIELLIDH-KACLDIEDCCGCTPLIIAMAKGDIAICKMLL-DSGANIDYFGKNGCVAALCYAIENNKIDIVRL 220
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
149-326 |
1.28e-05 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 47.65 E-value: 1.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 149 GDFPSLRLLVEHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQEcGADPHARAHDGMTPLHAAAQMGHSPVIVWL--- 225
Cdd:PHA02874 12 GDIEAIEKIIKNKGNCINISVDETTTPLIDAIRSGDAKIVELFIKH-GADINHINTKIPHPLLTAIKIGAHDIIKLLidn 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 226 --------VSCTD-----------VSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGGEIS-ADLWGGTPLHDAAENGEL 285
Cdd:PHA02874 91 gvdtsilpIPCIEkdmiktildcgIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNiEDDNGCYPIHIAIKHNFF 170
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 767906257 286 ECCQILVVNGAELDVRDRDGYTAADLSDFNGHSHCTRYLRT 326
Cdd:PHA02874 171 DIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACIKLLID 211
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
108-307 |
1.52e-05 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 47.35 E-value: 1.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 108 LHLAARFGHPEVVNWLLHHGGgDP--TAATDMGALPIH--YAAAKGDFPSLRLLVEHYPEGVNAQTKNGATPLYLACQE- 182
Cdd:PHA03100 39 LYLAKEARNIDVVKILLDNGA-DInsSTKNNSTPLHYLsnIKYNLTDVKEIVKLLLEYGANVNAPDNNGITPLLYAISKk 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 183 -GHLEVTQYLVQEcGADPHARAHDGMTPLHAAaqmghspvivwlVSCTDVSLseqdkdgatamhfaasrghtKVLSWLLL 261
Cdd:PHA03100 118 sNSYSIVEYLLDN-GANVNIKNSDGENLLHLY------------LESNKIDL--------------------KILKLLID 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767906257 262 HGGEISA-----------------DLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYT 307
Cdd:PHA03100 165 KGVDINAknrvnyllsygvpinikDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDT 227
|
|
| PHA02946 |
PHA02946 |
ankyin-like protein; Provisional |
94-250 |
2.58e-05 |
|
ankyin-like protein; Provisional
Pssm-ID: 165256 [Multi-domain] Cd Length: 446 Bit Score: 46.59 E-value: 2.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 94 GCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHgGGDPTAATDMGALPIHYAAAKGD--FPSLRLLVEHYPEGVNAQTKN 171
Cdd:PHA02946 62 GYSPNETDDDGNYPLHIASKINNNRIVAMLLTH-GADPNACDKQHKTPLYYLSGTDDevIERINLLVQYGAKINNSVDEE 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 172 GATPLyLACQEGHLEVTQYLVQeCGADPHARAHDGMTPLHAAAqMGHSP---VIVWLVScTDVSLSEQDKDGATAMHFAA 248
Cdd:PHA02946 141 GCGPL-LACTDPSERVFKKIMS-IGFEARIVDKFGKNHIHRHL-MSDNPkasTISWMMK-LGISPSKPDHDGNTPLHIVC 216
|
..
gi 767906257 249 SR 250
Cdd:PHA02946 217 SK 218
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
230-307 |
4.24e-05 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 46.03 E-value: 4.24e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767906257 230 DVSLSEQDKDgATAMHFAASRGHTKVLSWLLLHGGEI-SADLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYT 307
Cdd:PHA02878 159 DINMKDRHKG-NTALHYATENKDQRLTELLLSYGANVnIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNT 236
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
123-179 |
4.79e-05 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 41.18 E-value: 4.79e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 767906257 123 LLHHGGGDPTAATDMGALPIHYAAAKGDFPSLRLLVEhYPEGVNAQTKNGATPLYLA 179
Cdd:pfam13857 1 LLEHGPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLA-YGVDLNLKDEEGLTALDLA 56
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
39-90 |
9.17e-05 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 40.34 E-value: 9.17e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 767906257 39 PVHHAARAGKLHCLRFLVEeAALPAAARARNGATPAHDASATGHLACLQWLL 90
Cdd:pfam13637 4 ALHAAAASGHLELLRLLLE-KGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
157-213 |
9.92e-05 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 40.02 E-value: 9.92e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 767906257 157 LVEHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVqECGADPHARAHDGMTPLHAA 213
Cdd:pfam13857 1 LLEHGPIDLNRLDGEGYTPLHVAAKYGALEIVRVLL-AYGVDLNLKDEEGLTALDLA 56
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
183-324 |
1.99e-04 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 43.83 E-value: 1.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 183 GHLEVTQYLVqECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVSCTDVSlSEQDKDGATAMHFAASRGHTKVLSWLLLH 262
Cdd:PHA02875 13 GELDIARRLL-DIGINPNFEIYDGISPIKLAMKFRDSEAIKLLMKHGAIP-DVKYPDIESELHDAVEEGDVKAVEELLDL 90
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767906257 263 GGEISADLW--GGTPLHDAAENGELECCQILVVNGAELDVRDRDGYTAADLSDFNGHSHCTRYL 324
Cdd:PHA02875 91 GKFADDVFYkdGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELL 154
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
7-193 |
2.92e-04 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 43.46 E-value: 2.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 7 LQAARQGELDVLRSLhaagLLGPSL----RDPLDALPVHHAARAGKLHCLRFLVEEAALPAAARARN----GATPAHDAS 78
Cdd:cd22192 22 LLAAKENDVQAIKKL----LKCPSCdlfqRGALGETALHVAALYDNLEAAVVLMEAAPELVNEPMTSdlyqGETALHIAV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 79 ATGHLACLQWLLSQGG----------CRVQDKDN---SGATVLHLAARFGHPEVVNWLLHHGGgDPTAATDMGALPIHYA 145
Cdd:cd22192 98 VNQNLNLVRELIARGAdvvspratgtFFRPGPKNliyYGEHPLSFAACVGNEEIVRLLIEHGA-DIRAQDSLGNTVLHIL 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767906257 146 A-------------------AKGDFPSLRLLvehypegvnaQTKNGATPLYLACQEGHLEVTQYLVQ 193
Cdd:cd22192 177 VlqpnktfacqmydlilsydKEDDLQPLDLV----------PNNQGLTPFKLAAKEGNIVMFQHLVQ 233
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
40-181 |
3.09e-04 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 43.41 E-value: 3.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 40 VHHAARAGKLHCLRFLVEeAALPAAARARNGATPAHDASATGHLACLQWLLSQGGcRVQDKDNSGATVLHLAARFGHPEV 119
Cdd:PHA02874 128 LHYAIKKGDLESIKMLFE-YGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGA-YANVKDNNGESPLHNAAEYGDYAC 205
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767906257 120 VNWLLHHgGGDPTAATDMGALPIHYAAAKgDFPSLRLLVEHypEGVNAQTKNGATPLYLACQ 181
Cdd:PHA02874 206 IKLLIDH-GNHIMNKCKNGFTPLHNAIIH-NRSAIELLINN--ASINDQDIDGSTPLHHAIN 263
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
174-307 |
4.90e-04 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 42.69 E-value: 4.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 174 TPLYLACQEGHLEVTQYLVQECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVSCT----DVSLSEQDKDGATAMHFAAS 249
Cdd:cd22192 19 SPLLLAAKENDVQAIKKLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAApelvNEPMTSDLYQGETALHIAVV 98
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767906257 250 RGHTKVLSWLLLHGGEISADLWGGT---------------PLHDAAENGELECCQILVVNGAELDVRDRDGYT 307
Cdd:cd22192 99 NQNLNLVRELIARGADVVSPRATGTffrpgpknliyygehPLSFAACVGNEEIVRLLIEHGADIRAQDSLGNT 171
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
171-201 |
7.96e-04 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 36.80 E-value: 7.96e-04
10 20 30
....*....|....*....|....*....|.
gi 767906257 171 NGATPLYLACQEGHLEVTQYLVQEcGADPHA 201
Cdd:smart00248 1 DGRTPLHLAAENGNLEVVKLLLDK-GADINA 30
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
191-247 |
1.04e-03 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 37.33 E-value: 1.04e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 767906257 191 LVQECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVScTDVSLSEQDKDGATAMHFA 247
Cdd:pfam13857 1 LLEHGPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLA-YGVDLNLKDEEGLTALDLA 56
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
78-188 |
1.41e-03 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 41.42 E-value: 1.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 78 SATGHLACLQWLLSqGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHgGGDPTAATDMGALPIHYAAAKGDFPSLRLL 157
Cdd:PTZ00322 90 AASGDAVGARILLT-GGADPNCRDYDGRTPLHIACANGHVQVVRVLLEF-GADPTLLDKDGKTPLELAEENGFREVVQLL 167
|
90 100 110
....*....|....*....|....*....|.
gi 767906257 158 VEHYPEGVNAQTKngATPLYLACQEGHLEVT 188
Cdd:PTZ00322 168 SRHSQCHFELGAN--AKPDSFTGKPPSLEDS 196
|
|
| TRPV2 |
cd22197 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 2; TRPV2 is closely ... |
159-286 |
1.55e-03 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 2; TRPV2 is closely related to TRPV1, sharing high sequence identity (>50%), but TRPV2 shows a higher temperature threshold and sensitivity for activation than TRPV1. TRPV2 can be stimulated by ligands or lipids, and is involved in osmosensation and mechanosensation. TRPV2 is expressed in both neuronal and non-neuronal tissues, and it has been implicated in diverse physiological and pathophysiological processes, including cardiac-structure maintenance, innate immunity, and cancer. TRPV2 belongs to the vanilloid TRP subfamily (TRPV), named after the founding member vanilloid receptor 1 (TRPV1). The structure of TRPV shows the typical topology features of all Transient Receptor Potential (TRP) ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains.
Pssm-ID: 411981 [Multi-domain] Cd Length: 640 Bit Score: 41.38 E-value: 1.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 159 EHYPEGVNAQTKN----GATPLYLACQEGHLEVTQYLVqECGADPHARAHD-------------GMTPLHAAAQMGHSPV 221
Cdd:cd22197 77 GNPKPLVNAQCTDeyyrGHSALHIAIEKRSLQCVKLLV-ENGADVHARACGrffqkkqgtcfyfGELPLSLAACTKQWDV 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 222 IVWLVS--CTDVSLSEQDKDGATAMH---FAASRGH------TKVLSWLLLHGGEISADL-------WGG-TPLHDAAEN 282
Cdd:cd22197 156 VNYLLEnpHQPASLQAQDSLGNTVLHalvMIADNSPensalvIKMYDGLLQAGARLCPTVqleeisnHEGlTPLKLAAKE 235
|
....
gi 767906257 283 GELE 286
Cdd:cd22197 236 GKIE 239
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
104-128 |
2.09e-03 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 35.64 E-value: 2.09e-03
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
104-127 |
2.13e-03 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 35.70 E-value: 2.13e-03
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
171-202 |
2.65e-03 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 35.34 E-value: 2.65e-03
10 20 30
....*....|....*....|....*....|...
gi 767906257 171 NGATPLYLAC-QEGHLEVTQYLVQeCGADPHAR 202
Cdd:pfam00023 1 DGNTPLHLAAgRRGNLEIVKLLLS-KGADVNAR 32
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
123-203 |
2.78e-03 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 40.27 E-value: 2.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 123 LLHHGGGDPTAATDMGALPIHYAAAKGDFPSLRLLVEhYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHAR 202
Cdd:PTZ00322 100 ILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLE-FGADPTLLDKDGKTPLELAEENGFREVVQLLSRHSQCHFELG 178
|
.
gi 767906257 203 A 203
Cdd:PTZ00322 179 A 179
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
237-291 |
3.33e-03 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 40.27 E-value: 3.33e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 767906257 237 DKDGATAMHFAASRGHTKVLSWLLLHGGEISA-DLWGGTPLHDAAENGELECCQIL 291
Cdd:PTZ00322 112 DYDGRTPLHIACANGHVQVVRVLLEFGADPTLlDKDGKTPLELAEENGFREVVQLL 167
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
225-277 |
3.50e-03 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 35.79 E-value: 3.50e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 767906257 225 LVSCTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGGEISA-DLWGGTPLH 277
Cdd:pfam13857 1 LLEHGPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLkDEEGLTALD 54
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
7-223 |
5.14e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 39.66 E-value: 5.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 7 LQAARQGELDVLRSLHAAGLLGPSLrDPLDALPVHHAARAGKLHCLRFLVEEAALPAAARARNGATPAHDASATGH-LAC 85
Cdd:PHA02876 245 LKAIRNEDLETSLLLYDAGFSVNSI-DDCKNTPLHHASQAPSLSRLVPKLLERGADVNAKNIKGETPLYLMAKNGYdTEN 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767906257 86 LQWLLSQGGcRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGGGDPTAATDMGALPIHYAAAKGDFPSLRLLVEhYPEGV 165
Cdd:PHA02876 324 IRTLIMLGA-DVNAADRLYITPLHQASTLDRNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLD-YGADI 401
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 767906257 166 NAQTKNGATPLYLA-CQEGHLEVTQYLVQEcGADPHARAHDGMTPLHAAAQMGHSPVIV 223
Cdd:PHA02876 402 EALSQKIGTALHFAlCGTNPYMSVKTLIDR-GANVNSKNKDLSTPLHYACKKNCKLDVI 459
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
245-316 |
5.34e-03 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 39.50 E-value: 5.34e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767906257 245 HFAASrGHTkVLSWLLLHGGEI--SADLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYTAADLSDFNG 316
Cdd:PTZ00322 88 QLAAS-GDA-VGARILLTGGADpnCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENG 159
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
239-268 |
9.14e-03 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 33.77 E-value: 9.14e-03
10 20 30
....*....|....*....|....*....|
gi 767906257 239 DGATAMHFAASRGHTKVLSWLLLHGGEISA 268
Cdd:pfam13606 1 DGNTPLHLAARNGRLEIVKLLLENGADINA 30
|
|
|