|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
89-329 |
1.26e-14 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 75.89 E-value: 1.26e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 89 LSRVPAGLPRSLVLLHLEKNAIRSVDANvltpirsleyllLHSNqlreqgihplafqglkrLHTVHLYNNALERVPSGLP 168
Cdd:PRK15370 190 LTTIPACIPEQITTLILDNNELKSLPEN------------LQGN-----------------IKTLYANSNQLTSIPATLP 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 169 RRVRTLMILHNQITGIgREDFATTyfLEELNLSYNRITS-PQVHRDAFRKLRLLRsldlsgNRLHTLPPGLPRNVHVLKV 247
Cdd:PRK15370 241 DTIQEMELSINRITEL-PERLPSA--LQSLDLFHNKISClPENLPEELRYLSVYD------NSIRTLPAHLPSGITHLNV 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 248 KRNELAALARGALVGmaqLRELYLTSNRLRS--RALGPRawvdlahLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISA 325
Cdd:PRK15370 312 QSNSLTALPETLPPG---LKTLEAGENALTSlpASLPPE-------LQVLDVSKNQITVLPETLPPTITTLDVSRNALTN 381
|
....
gi 767902357 326 VPAN 329
Cdd:PRK15370 382 LPEN 385
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
1-377 |
3.34e-14 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 74.50 E-value: 3.34e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 1 MFNGSSNVEVLILSSN-FLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTdeGLDNETFWKLSSL 79
Cdd:PLN00113 113 IFTTSSSLRYLNLSNNnFTGSIPRGSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLV--GKIPNSLTNLTSL 190
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 80 EYLDLSSNNLS-RVPA--GLPRSLVLLHLEKNAIRS-----------------VDANVLTPIRS-------LEYLLLHSN 132
Cdd:PLN00113 191 EFLTLASNQLVgQIPRelGQMKSLKWIYLGYNNLSGeipyeiggltslnhldlVYNNLTGPIPSslgnlknLQYLFLYQN 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 133 QLREQgIHPLAFqGLKRLHTVHLYNNALERVPSGLPRRVRTLMILH---NQITGIGREDFATTYFLEELNLSYNRItSPQ 209
Cdd:PLN00113 271 KLSGP-IPPSIF-SLQKLISLDLSDNSLSGEIPELVIQLQNLEILHlfsNNFTGKIPVALTSLPRLQVLQLWSNKF-SGE 347
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 210 VHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVK--RNELAALARGALVGMAQLRELYLTSNRLRSRAlgPRAWV 287
Cdd:PLN00113 348 IPKNLGKHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLIlfSNSLEGEIPKSLGACRSLRRVRLQDNSFSGEL--PSEFT 425
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 288 DLAHLQLLDIAGNQLT--------EIPeglpeSLEYLYLQNNKISAVPANAFDSTpNLKGIFLRFNKLAvgSVVDSAFRR 359
Cdd:PLN00113 426 KLPLVYFLDISNNNLQgrinsrkwDMP-----SLQMLSLARNKFFGGLPDSFGSK-RLENLDLSRNQFS--GAVPRKLGS 497
|
410
....*....|....*...
gi 767902357 360 LKHLQVLDIEGNLEFGDI 377
Cdd:PLN00113 498 LSELMQLKLSENKLSGEI 515
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
3-381 |
5.36e-14 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 73.73 E-value: 5.36e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 3 NGSSNVEVLILSSnflRHVPKHLPPALYKL------HLKNNKLE-KIPPGAFSELSSLRELYLQNNYLTdeGLDNETFwk 75
Cdd:PLN00113 66 NNSSRVVSIDLSG---KNISGKISSAIFRLpyiqtiNLSNNQLSgPIPDDIFTTSSSLRYLNLSNNNFT--GSIPRGS-- 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 76 LSSLEYLDLSSNNLS-RVPA--GLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLreQGIHPLAFQGLKRLHT 152
Cdd:PLN00113 139 IPNLETLDLSNNMLSgEIPNdiGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQL--VGQIPRELGQMKSLKW 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 153 VHL-YNNALERVPSGLPR--RVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPqVHRDAFrKLRLLRSLDLSGN 229
Cdd:PLN00113 217 IYLgYNNLSGEIPYEIGGltSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGP-IPPSIF-SLQKLISLDLSDN 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 230 RLHTLPPGLP---RNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRS---RALGPRawvdlAHLQLLDIAGNQLT 303
Cdd:PLN00113 295 SLSGEIPELViqlQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGeipKNLGKH-----NNLTVLDLSTNNLT 369
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 304 -EIPEGLPES--LEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAvgSVVDSAFRRLKHLQVLDIEGNLEFGDISKD 380
Cdd:PLN00113 370 gEIPEGLCSSgnLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFS--GELPSEFTKLPLVYFLDISNNNLQGRINSR 447
|
.
gi 767902357 381 R 381
Cdd:PLN00113 448 K 448
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
3-324 |
1.15e-13 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 71.89 E-value: 1.15e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 3 NGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNyltdegldnETFWKLSSLEYL 82
Cdd:COG4886 48 LLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN---------EELSNLTNLESL 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 83 DLSSNNLSRVPAGLPR--SLVLLHLEKNAIRSVDAnVLTPIRSLEYLLLHSNQLREQgihPLAFQGLKRLHTVHLYNNAL 160
Cdd:COG4886 119 DLSGNQLTDLPEELANltNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNNQLTDL---PEELGNLTNLKELDLSNNQI 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 161 ERVPSGLPRRVRtlmilhnqitgigredfattyfLEELNLSYNRITSpqvhrdafrklrllrsldlsgnrlhtLPPGLPR 240
Cdd:COG4886 195 TDLPEPLGNLTN----------------------LEELDLSGNQLTD--------------------------LPEPLAN 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 241 nvhvlkvkrnelaalargalvgMAQLRELYLTSNRLRS-RALGprawvDLAHLQLLDIAGNQLTEIPEGLP-ESLEYLYL 318
Cdd:COG4886 227 ----------------------LTNLETLDLSNNQLTDlPELG-----NLTNLEELDLSNNQLTDLPPLANlTNLKTLDL 279
|
....*.
gi 767902357 319 QNNKIS 324
Cdd:COG4886 280 SNNQLT 285
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
10-347 |
2.98e-13 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 70.73 E-value: 2.98e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 10 VLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNL 89
Cdd:COG4886 2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 90 SRVPAGLPRSLVLLhLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQgihPLAFQGLKRLHTVHLYNNALERVPSGLPR 169
Cdd:COG4886 82 LSLLLLGLTDLGDL-TNLTELDLSGNEELSNLTNLESLDLSGNQLTDL---PEELANLTNLKELDLSNNQLTDLPEPLGN 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 170 --RVRTLMILHNQITGIGREdFATTYFLEELNLSYNRITSpqvhrdafrklrllrsldlsgnrlhtLPPglprnvhvlkv 247
Cdd:COG4886 158 ltNLKSLDLSNNQLTDLPEE-LGNLTNLKELDLSNNQITD--------------------------LPE----------- 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 248 krnelaalargALVGMAQLRELYLTSNRLRSRalgPRAWVDLAHLQLLDIAGNQLTEIPE--GLPeSLEYLYLQNNKISA 325
Cdd:COG4886 200 -----------PLGNLTNLEELDLSGNQLTDL---PEPLANLTNLETLDLSNNQLTDLPElgNLT-NLEELDLSNNQLTD 264
|
330 340
....*....|....*....|..
gi 767902357 326 VPANAfdSTPNLKGIFLRFNKL 347
Cdd:COG4886 265 LPPLA--NLTNLKTLDLSNNQL 284
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
18-255 |
3.02e-13 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 71.27 E-value: 3.02e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 18 LRHVPKHLPPALYKLHLKNNKLEKIPPGAFSelsSLRELYLQNNYLTD--EGLDNetfwklsSLEYLDLSSNNLSRVPAG 95
Cdd:PRK15370 190 LTTIPACIPEQITTLILDNNELKSLPENLQG---NIKTLYANSNQLTSipATLPD-------TIQEMELSINRITELPER 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 96 LPRSLVLLHLEKNAIRSVDANVltPiRSLEYLLLHSNQLREQGIH-PLAFQGLkrlhtvHLYNNALERVPSGLPRRVRTL 174
Cdd:PRK15370 260 LPSALQSLDLFHNKISCLPENL--P-EELRYLSVYDNSIRTLPAHlPSGITHL------NVQSNSLTALPETLPPGLKTL 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 175 MILHNQITGIGRedfATTYFLEELNLSYNRITS-PQVHRDAFRKLRLLRsldlsgNRLHTLPPGLPRNVHVLKVKRNELA 253
Cdd:PRK15370 331 EAGENALTSLPA---SLPPELQVLDVSKNQITVlPETLPPTITTLDVSR------NALTNLPENLPAALQIMQASRNNLV 401
|
..
gi 767902357 254 AL 255
Cdd:PRK15370 402 RL 403
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
27-89 |
2.40e-12 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 61.39 E-value: 2.40e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767902357 27 PALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTdeGLDNETFWKLSSLEYLDLSSNNL 89
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLT--TLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
11-213 |
6.31e-11 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 61.73 E-value: 6.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 11 LILSSNFLRHVPK-HLPPALYKLHLKNNKLEKIPpgAFSELSSLRELYLQNNYLTD-EGLDNetfwkLSSLEYLDLSSNN 88
Cdd:cd21340 7 LYLNDKNITKIDNlSLCKNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKiENLEN-----LVNLKKLYLGGNR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 89 LSRVpAGL--PRSLVLLHLEKNAIRS-----VDANVLTPI-RSLEYLLLHSNQLREqgIHPLAfqGLKRLhtvhlynnal 160
Cdd:cd21340 80 ISVV-EGLenLTNLEELHIENQRLPPgekltFDPRSLAALsNSLRVLNISGNNIDS--LEPLA--PLRNL---------- 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 767902357 161 ervpsglprrvRTLMILHNQITGIGR--EDFATTYFLEELNLSYNRITSPQVHRD 213
Cdd:cd21340 145 -----------EQLDASNNQISDLEEllDLLSSWPSLRELDLTGNPVCKKPKYRD 188
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
6-206 |
1.12e-10 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 63.33 E-value: 1.12e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 6 SNVEVLILSSNFLR-HVPKHLPPA--LYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEgLDNEtFWKLSSLEYL 82
Cdd:PLN00113 356 NNLTVLDLSTNNLTgEIPEGLCSSgnLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGE-LPSE-FTKLPLVYFL 433
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 83 DLSSNNLS-RVPAG---LPrSLVLLHLEKNairSVDANVLTPIRS--LEYLLLHSNQLreQGIHPLAFQGLKRLHTVHLY 156
Cdd:PLN00113 434 DISNNNLQgRINSRkwdMP-SLQMLSLARN---KFFGGLPDSFGSkrLENLDLSRNQF--SGAVPRKLGSLSELMQLKLS 507
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 767902357 157 NNALE-RVPSGLP--RRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRIT 206
Cdd:PLN00113 508 ENKLSgEIPDELSscKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLS 560
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
7-97 |
8.69e-10 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 60.48 E-value: 8.69e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 7 NVEVLILSSNFLRHVPKHLPPALYKLHLKNNKL----EKIPPgafselsSLRELYLQNNYLTD--EGLDnetfwklSSLE 80
Cdd:PRK15370 326 GLKTLEAGENALTSLPASLPPELQVLDVSKNQItvlpETLPP-------TITTLDVSRNALTNlpENLP-------AALQ 391
|
90
....*....|....*..
gi 767902357 81 YLDLSSNNLSRVPAGLP 97
Cdd:PRK15370 392 IMQASRNNLVRLPESLP 408
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
23-206 |
4.85e-09 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 57.37 E-value: 4.85e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 23 KHLPPALYKLHLKNNKLEKIPPG------AFSELSSLRELYLQNNYLTDEGLDN-ETFWKLSSLEYLDLSSNNLS----- 90
Cdd:cd00116 47 LRPQPSLKELCLSLNETGRIPRGlqsllqGLTKGCGLQELDLSDNALGPDGCGVlESLLRSSSLQELKLNNNGLGdrglr 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 91 ---RVPAGLPRSLVLLHLEKNAIRSVD----ANVLTPIRSLEYLLLHSNQLREQGIHPLAfQGLK---RLHTVHLYNNAL 160
Cdd:cd00116 127 llaKGLKDLPPALEKLVLGRNRLEGAScealAKALRANRDLKELNLANNGIGDAGIRALA-EGLKancNLEVLDLNNNGL 205
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 767902357 161 ERVPSGL-------PRRVRTLMILHNQITGIGREDFATTYF-----LEELNLSYNRIT 206
Cdd:cd00116 206 TDEGASAlaetlasLKSLEVLNLGDNNLTDAGAAALASALLspnisLLTLSLSCNDIT 263
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
79-345 |
1.11e-08 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 57.09 E-value: 1.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 79 LEYLDLSSNNLSRVPAgLPRSLVLLHLEKNAIRSVDAnvlTPiRSLEYLLLHSNQLREQGIHPLAFQGLKrlhtvhLYNN 158
Cdd:PRK15387 244 LRTLEVSGNQLTSLPV-LPPGLLELSIFSNPLTHLPA---LP-SGLCKLWIFGNQLTSLPVLPPGLQELS------VSDN 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 159 ALERVPSgLPRRVRTLMILHNQITGIGredfATTYFLEELNLSYNRITS-PQVHRDAFRklrllrsLDLSGNRLHTLPpG 237
Cdd:PRK15387 313 QLASLPA-LPSELCKLWAYNNQLTSLP----TLPSGLQELSVSDNQLASlPTLPSELYK-------LWAYNNRLTSLP-A 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 238 LPRNVHVLKVKRNELAALArgalVGMAQLRELYLTSNRLRSRALGPRAWVDLAhlqlldIAGNQLTEIPEGLPE--SLEY 315
Cdd:PRK15387 380 LPSGLKELIVSGNRLTSLP----VLPSELKELMVSGNRLTSLPMLPSGLLSLS------VYRNQLTRLPESLIHlsSETT 449
|
250 260 270
....*....|....*....|....*....|...
gi 767902357 316 LYLQNNKISAVPANAF---DSTPNLKGIFLRFN 345
Cdd:PRK15387 450 VNLEGNPLSERTLQALreiTSAPGYSGPIIRFD 482
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
203-329 |
1.44e-08 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 56.63 E-value: 1.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 203 NRITSPQVHRDAFRKLRLLRSLDLSGnrLHTLPPGLPRNVHVLKVKRNELAALARGAlvgMAQLRELYLTSNRLRS---- 278
Cdd:PRK15370 164 NREEAVQRMRDCLKNNKTELRLKILG--LTTIPACIPEQITTLILDNNELKSLPENL---QGNIKTLYANSNQLTSipat 238
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767902357 279 -------RALGPRAWVDL-----AHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPAN 329
Cdd:PRK15370 239 lpdtiqeMELSINRITELperlpSALQSLDLFHNKISCLPENLPEELRYLSVYDNSIRTLPAH 301
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
148-371 |
1.95e-08 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 56.24 E-value: 1.95e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 148 KRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIgREDFATTyfLEELNLSYNRITSpqvhrdafrklrllrsldls 227
Cdd:PRK15370 199 EQITTLILDNNELKSLPENLQGNIKTLYANSNQLTSI-PATLPDT--IQEMELSINRITE-------------------- 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 228 gnrlhtLPPGLPRNVHVLKVKRNELAALargalvgmaqlrelyltsnrlrsralgPRAWVDlaHLQLLDIAGNQLTEIPE 307
Cdd:PRK15370 256 ------LPERLPSALQSLDLFHNKISCL---------------------------PENLPE--ELRYLSVYDNSIRTLPA 300
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767902357 308 GLPESLEYLYLQNNKISAVPANAfdsTPNLKgiFLRFNKLAVGSVVDSAfrrLKHLQVLDIEGN 371
Cdd:PRK15370 301 HLPSGITHLNVQSNSLTALPETL---PPGLK--TLEAGENALTSLPASL---PPELQVLDVSKN 356
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
6-281 |
5.49e-08 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 54.78 E-value: 5.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 6 SNVEVLILSSNFLRHVPKhLPPALYKLHLKNNKLEKIP---PGafselssLRELYLQNNYLTD-EGLDnetfwklSSLEY 81
Cdd:PRK15387 222 AHITTLVIPDNNLTSLPA-LPPELRTLEVSGNQLTSLPvlpPG-------LLELSIFSNPLTHlPALP-------SGLCK 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 82 LDLSSNNLSRVPAgLPRSLVLLHLEKNAIRSVDAnvlTPiRSLEYLLLHSNQLREQGIHPLAFQGLKrlhtvhLYNNALE 161
Cdd:PRK15387 287 LWIFGNQLTSLPV-LPPGLQELSVSDNQLASLPA---LP-SELCKLWAYNNQLTSLPTLPSGLQELS------VSDNQLA 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 162 RVPSgLPRRVRTLMILHNQITGIGredfATTYFLEELNLSYNRITSPQVHRDAFRKLRLLrsldlsGNRLHTLPPgLPRN 241
Cdd:PRK15387 356 SLPT-LPSELYKLWAYNNRLTSLP----ALPSGLKELIVSGNRLTSLPVLPSELKELMVS------GNRLTSLPM-LPSG 423
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 767902357 242 VHVLKVKRNELAALARgALVGMAQLRELYLTSNRLRSRAL 281
Cdd:PRK15387 424 LLSLSVYRNQLTRLPE-SLIHLSSETTVNLEGNPLSERTL 462
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
32-229 |
6.99e-07 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 49.78 E-value: 6.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 32 LHLKNNKLEKIppGAFSELSSLRELYLQNNYLTD-EGLDNetfwkLSSLEYLDLSSNNLSRVP--AGLPRsLVLLHLEKN 108
Cdd:cd21340 7 LYLNDKNITKI--DNLSLCKNLKVLYLYDNKITKiENLEF-----LTNLTHLYLQNNQIEKIEnlENLVN-LKKLYLGGN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 109 AIRSVDAnvLTPIRSLEYLLLHSNQLREQgiHPLAFQglkrlhtvhlynnalERVPSGLPRRVRTLMILHNQITGIgrED 188
Cdd:cd21340 79 RISVVEG--LENLTNLEELHIENQRLPPG--EKLTFD---------------PRSLAALSNSLRVLNISGNNIDSL--EP 137
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 767902357 189 FATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGN 229
Cdd:cd21340 138 LAPLRNLEQLDASNNQISDLEELLDLLSSWPSLRELDLTGN 178
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
240-302 |
9.70e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.59 E-value: 9.70e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767902357 240 RNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSraLGPRAWVDLAHLQLLDIAGNQL 302
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT--LSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
152-360 |
1.11e-06 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 50.93 E-value: 1.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 152 TVHLYNNALERVPSgLPRRVRTLMILHNQITGIGredfattyFLEELNLSYNRITSPQVHRDAFrkLRLLRSLDLSGNRL 231
Cdd:PRK15387 226 TLVIPDNNLTSLPA-LPPELRTLEVSGNQLTSLP--------VLPPGLLELSIFSNPLTHLPAL--PSGLCKLWIFGNQL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 232 HTLPPgLPRNVHVLKVKRNELAALArgALVgmAQLRELYLTSNRLRSRALGPRAwvdlahLQLLDIAGNQLTEIPEgLPE 311
Cdd:PRK15387 295 TSLPV-LPPGLQELSVSDNQLASLP--ALP--SELCKLWAYNNQLTSLPTLPSG------LQELSVSDNQLASLPT-LPS 362
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 767902357 312 SLEYLYLQNNKISAVPAnafdSTPNLKGIFLRFNKLAVGSVVDSAFRRL 360
Cdd:PRK15387 363 ELYKLWAYNNRLTSLPA----LPSGLKELIVSGNRLTSLPVLPSELKEL 407
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
51-134 |
2.19e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 44.44 E-value: 2.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 51 SSLRELYLQNNYLTDegLDNETFWKLSSLEYLDLSSNNLSrvpaglprslvllhleknairSVDANVLTPIRSLEYLLLH 130
Cdd:pfam13855 1 PNLRSLDLSNNRLTS--LDDGAFKGLSNLKVLDLSNNLLT---------------------TLSPGAFSGLPSLRYLDLS 57
|
....
gi 767902357 131 SNQL 134
Cdd:pfam13855 58 GNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
312-372 |
4.94e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 43.67 E-value: 4.94e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767902357 312 SLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLavGSVVDSAFRRLKHLQVLDIEGNL 372
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL--TTLSPGAFSGLPSLRYLDLSGNR 60
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
25-313 |
5.78e-06 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 48.25 E-value: 5.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 25 LPPALYKLHLKNNK-LEKIPPGafseLSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPA-------GL 96
Cdd:COG5238 131 LILYLALPRRINLIqVLKDPLG----GNAVHLLGLAARLGLLAAISMAKALQNNSVETVYLGCNQIGDEGIeelaealTQ 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 97 PRSLVLLHLEKNAI--RSVD--ANVLTPIRSLEYLLLHSNQLREQGIHPLA--FQGLKRLHTVHLYNN-----ALERVPS 165
Cdd:COG5238 207 NTTVTTLWLKRNPIgdEGAEilAEALKGNKSLTTLDLSNNQIGDEGVIALAeaLKNNTTVETLYLSGNqigaeGAIALAK 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 166 GLPRR--VRTLMILHNQITGIGREDFA----TTYFLEELNLSYNRITSPQVHRDAfrklrllrsldlsgnrlHTLPPGlp 239
Cdd:COG5238 287 ALQGNttLTSLDLSVNRIGDEGAIALAeglqGNKTLHTLNLAYNGIGAQGAIALA-----------------KALQEN-- 347
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 240 RNVHVLKVKRNEL-----AALARgALVGMAQLRELyltsnRLRSRALGPRAWVDLA-HLQL-----LDIAGNQLTEIPEG 308
Cdd:COG5238 348 TTLHSLDLSDNQIgdegaIALAK-YLEGNTTLREL-----NLGKNNIGKQGAEALIdALQTnrlhtLILDGNLIGAEAQQ 421
|
....*
gi 767902357 309 LPESL 313
Cdd:COG5238 422 RLEQL 426
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
2-207 |
6.32e-06 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 47.86 E-value: 6.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 2 FNGSSNVEVLILSSNFL-----RHVPKHL--PPALYKLHLKNNKLE----KIPPGAFSELSSLRELYLQNNYLTDEGLDN 70
Cdd:COG5238 176 ALQNNSVETVYLGCNQIgdegiEELAEALtqNTTVTTLWLKRNPIGdegaEILAEALKGNKSLTTLDLSNNQIGDEGVIA 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 71 --ETFWKLSSLEYLDLSSNNLSrvpaglprslvllhlEKNAIRSvdANVLTPIRSLEYLLLHSNQLREQGIHPLA--FQG 146
Cdd:COG5238 256 laEALKNNTTVETLYLSGNQIG---------------AEGAIAL--AKALQGNTTLTSLDLSVNRIGDEGAIALAegLQG 318
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767902357 147 LKRLHTVHL-YNNALERVPSGLPRRVRTLMILH------NQITGIGREDFATtyFLE------ELNLSYNRITS 207
Cdd:COG5238 319 NKTLHTLNLaYNGIGAQGAIALAKALQENTTLHsldlsdNQIGDEGAIALAK--YLEgnttlrELNLGKNNIGK 390
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
265-323 |
8.23e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 42.90 E-value: 8.23e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767902357 265 QLRELYLTSNRLRSraLGPRAWVDLAHLQLLDIAGNQLTEIPE----GLPeSLEYLYLQNNKI 323
Cdd:pfam13855 2 NLRSLDLSNNRLTS--LDDGAFKGLSNLKVLDLSNNLLTTLSPgafsGLP-SLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
5-163 |
5.42e-05 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 44.65 E-value: 5.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 5 SSNVEVLILSSN--------FLRHVPKHLPPALYKLHLKNNKLEKIP----PGAFSELSSLRELYLQNNYLTDEGLDN-- 70
Cdd:cd00116 107 SSSLQELKLNNNglgdrglrLLAKGLKDLPPALEKLVLGRNRLEGAScealAKALRANRDLKELNLANNGIGDAGIRAla 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 71 ETFWKLSSLEYLDLSSNnlsrvpaglprslVLLHLEKNAIrsvdANVLTPIRSLEYLLLHSNQLREQGIHPLAFQ---GL 147
Cdd:cd00116 187 EGLKANCNLEVLDLNNN-------------GLTDEGASAL----AETLASLKSLEVLNLGDNNLTDAGAAALASAllsPN 249
|
170
....*....|....*.
gi 767902357 148 KRLHTVHLYNNALERV 163
Cdd:cd00116 250 ISLLTLSLSCNDITDD 265
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
291-347 |
8.61e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 40.20 E-value: 8.61e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 291 HLQLLDIAGNQLTEIPEGL---PESLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKL 347
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAfkgLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
231-328 |
2.99e-04 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 43.23 E-value: 2.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 231 LHTLPPGLPRNVHVLKVKRNELAALArgALVgmAQLRELYLTSNRLRSRALGPRAWVDLA-------HLQLLD------- 296
Cdd:PRK15387 213 LTTLPDCLPAHITTLVIPDNNLTSLP--ALP--PELRTLEVSGNQLTSLPVLPPGLLELSifsnpltHLPALPsglcklw 288
|
90 100 110
....*....|....*....|....*....|..
gi 767902357 297 IAGNQLTEIPEgLPESLEYLYLQNNKISAVPA 328
Cdd:PRK15387 289 IFGNQLTSLPV-LPPGLQELSVSDNQLASLPA 319
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
6-164 |
3.03e-04 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 42.61 E-value: 3.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 6 SNVEVLILSSNFLRHVP--KHLPpALYKLHLKNNKLEKIPPGAfsELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLD 83
Cdd:COG4886 228 TNLETLDLSNNQLTDLPelGNLT-NLEELDLSNNQLTDLPPLA--NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLL 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 84 LSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERV 163
Cdd:COG4886 305 LLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLAL 384
|
.
gi 767902357 164 P 164
Cdd:COG4886 385 L 385
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
55-376 |
4.97e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 41.57 E-value: 4.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 55 ELYLQNNYLTDEGLDnETFWKLSSLEYLDLSSNNLSRVPAglprslvllhleknairSVDANVLTPIRSLEYLLLHSNQL 134
Cdd:cd00116 2 QLSLKGELLKTERAT-ELLPKLLCLQVLRLEGNTLGEEAA-----------------KALASALRPQPSLKELCLSLNET 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 135 REQ----GIHPLAFQGLKRLHTVHLYNNALervpsglprrvrtlmilhnQITGIGR-EDFATTYFLEELNLSYNRItspq 209
Cdd:cd00116 64 GRIprglQSLLQGLTKGCGLQELDLSDNAL-------------------GPDGCGVlESLLRSSSLQELKLNNNGL---- 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 210 vhrdafrklrllrsLDLSGNRLHTLPPGLPRNVHVLKVKRNEL-----AALArGALVGMAQLRELYLTSNRLRS---RAL 281
Cdd:cd00116 121 --------------GDRGLRLLAKGLKDLPPALEKLVLGRNRLegascEALA-KALRANRDLKELNLANNGIGDagiRAL 185
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 282 GpRAWVDLAHLQLLDIAGNQLTE-----IPEGLPE--SLEYLYLQNNKISAVPANAFDS-----TPNLKGIFLRFNKLAV 349
Cdd:cd00116 186 A-EGLKANCNLEVLDLNNNGLTDegasaLAETLASlkSLEVLNLGDNNLTDAGAAALASallspNISLLTLSLSCNDITD 264
|
330 340
....*....|....*....|....*....
gi 767902357 350 GSVVDSA--FRRLKHLQVLDIEGNlEFGD 376
Cdd:cd00116 265 DGAKDLAevLAEKESLLELDLRGN-KFGE 292
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
6-174 |
8.24e-04 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 41.69 E-value: 8.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 6 SNVEVLILSSNFLRHVPKhLPPALYKLHLKNNKLEKIPpgafSELSSLRELYLQNNYLTDEGLdnetfwKLSSLEYLDLS 85
Cdd:PRK15387 342 SGLQELSVSDNQLASLPT-LPSELYKLWAYNNRLTSLP----ALPSGLKELIVSGNRLTSLPV------LPSELKELMVS 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 86 SNNLSRVPAgLPRSLVLLHLEKNAIRSVDANvLTPIRSLEYLLLHSNQLREQgihplAFQGLKRLHTVHLYNNAL---ER 162
Cdd:PRK15387 411 GNRLTSLPM-LPSGLLSLSVYRNQLTRLPES-LIHLSSETTVNLEGNPLSER-----TLQALREITSAPGYSGPIirfDM 483
|
170
....*....|..
gi 767902357 163 VPSGLPRRVRTL 174
Cdd:PRK15387 484 AGASAPRETRAL 495
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
103-345 |
1.06e-03 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 40.15 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 103 LHLEKNAIRSVDAnvLTPIRSLEYLLLHSNQLREqgIHPLAFqgLKRLHTVHLYNNALERVP--SGLPRrvrtlmilhnq 180
Cdd:cd21340 7 LYLNDKNITKIDN--LSLCKNLKVLYLYDNKITK--IENLEF--LTNLTHLYLQNNQIEKIEnlENLVN----------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 181 itgigredfattyfLEELNLSYNRITspqvhrdafrklrllrsldlsgnrlhtlppglprnvhVLKvkrnelaalargAL 260
Cdd:cd21340 70 --------------LKKLYLGGNRIS-------------------------------------VVE------------GL 86
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902357 261 VGMAQLRELYLTSNRLRSR---ALGPRAWVDLAH-LQLLDIAGNQLTEIpEGLP--ESLEYLYLQNNKISAVP--ANAFD 332
Cdd:cd21340 87 ENLTNLEELHIENQRLPPGeklTFDPRSLAALSNsLRVLNISGNNIDSL-EPLAplRNLEQLDASNNQISDLEelLDLLS 165
|
250
....*....|...
gi 767902357 333 STPNLKGIFLRFN 345
Cdd:cd21340 166 SWPSLRELDLTGN 178
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
29-96 |
2.01e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 40.18 E-value: 2.01e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767902357 29 LYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTdeGLDNETFWKLSSLEYLDLSSNNLS-RVPAGL 96
Cdd:PLN03150 444 LQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFN--GSIPESLGQLTSLRILNLNGNSLSgRVPAAL 510
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
228-276 |
2.86e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 35.96 E-value: 2.86e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 767902357 228 GNRLHTLPPGLPRNVHVLKV---KRNELAALARGALVGMAQLRELYLTSNRL 276
Cdd:pfam13855 10 NNRLTSLDDGAFKGLSNLKVldlSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
52-89 |
6.47e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 34.53 E-value: 6.47e-03
10 20 30
....*....|....*....|....*....|....*...
gi 767902357 52 SLRELYLQNNYLTDEGLdnetFWKLSSLEYLDLSSNNL 89
Cdd:pfam12799 2 NLEVLDLSNNQITDIPP----LAKLPNLETLDLSGNNK 35
|
|
| |
