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Conserved domains on  [gi|767982370|ref|XP_011535734|]
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tetratricopeptide repeat protein 6 isoform X7 [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 18770047)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  30708253|10517866
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
995-1158 5.58e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 99.31  E-value: 5.58e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  995 KYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLK 1073
Cdd:COG0457     2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYeEALADYEQALELDPDDAEALNN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1074 RGLFYCENENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNNWLALYYRG-CLFRKSNPF 1152
Cdd:COG0457    82 LGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGiALEKLGRYE 161


                  ....*.
gi 767982370 1153 RALQDY 1158
Cdd:COG0457   162 EALELL 167
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 933-1034 1.88e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 57.12  E-value: 1.88e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  933 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYR 1012
Cdd:COG4783    38 PEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYR 117

                          90       100
                  ....*....|....*....|..
gi 767982370 1013 GKKDITLAILNYTQAIKSTPTD 1034
Cdd:COG4783   118 ALGRPDEAIAALEKALELDPDD 139
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
995-1158 5.58e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 99.31  E-value: 5.58e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  995 KYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLK 1073
Cdd:COG0457     2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYeEALADYEQALELDPDDAEALNN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1074 RGLFYCENENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNNWLALYYRG-CLFRKSNPF 1152
Cdd:COG0457    82 LGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGiALEKLGRYE 161


                  ....*.
gi 767982370 1153 RALQDY 1158
Cdd:COG0457   162 EALELL 167
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 933-1034 1.88e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 57.12  E-value: 1.88e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  933 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYR 1012
Cdd:COG4783    38 PEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYR 117

                          90       100
                  ....*....|....*....|..
gi 767982370 1013 GKKDITLAILNYTQAIKSTPTD 1034
Cdd:COG4783   118 ALGRPDEAIAALEKALELDPDD 139
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 915-1135 5.18e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.40  E-value: 5.18e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370   915 ESEVKILTEEIndKTKYPAF--AYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNY 992
Cdd:TIGR02917  175 FDEARALIDEV--LTADPGNvdALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADA 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370   993 IHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRG-EMYEITNKVLAIDDFSKCIFYDPKRTDAL 1071
Cdd:TIGR02917  253 LLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGaSEYQLGNLEQAYQYLNQILKYAPNSHQAR 332

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767982370  1072 LKRGLFYCENENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNN 1135
Cdd:TIGR02917  333 RLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPEN 396
PRK11189 PRK11189
lipoprotein NlpI; Provisional
 1014-1155 1.39e-05

lipoprotein NlpI; Provisional


Pssm-ID: 236875 [Multi-domain]  Cd Length: 296  Bit Score: 48.35  E-value: 1.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1014 KKDITLAILNytQAIKSTP-TD---ADIYFRRGEMYEitnKV----LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWF 1085
Cdd:PRK11189   41 QQEVILARLN--QILASRDlTDeerAQLHYERGVLYD---SLglraLARNDFSQALALRPDMADAYNYLGIYLTQAGNFD 115

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1086 AAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNnwlalyyrgclfrksNPFRAL 1155
Cdd:PRK11189  116 AAYEAFDSVLELDPTYNYAYLNRGIALYYGGRYELAQDDLLAFYQDDPN---------------DPYRAL 170
TPR_1 pfam00515
Tetratricopeptide repeat;
933-964 1.86e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 39.71  E-value: 1.86e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 767982370   933 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEP 964
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNP 32
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 933-964 6.25e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 38.20  E-value: 6.25e-04
                            10        20        30
                    ....*....|....*....|....*....|..
gi 767982370    933 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEP 964
Cdd:smart00028    1 AEALYNLGNAYLKLGDYDEALEYYEKALELDP 32
TPR_11 pfam13414
TPR repeat;
1010-1046 2.36e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.68  E-value: 2.36e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 767982370  1010 IYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYE 1046
Cdd:pfam13414    3 AYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYY 39
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
995-1158 5.58e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 99.31  E-value: 5.58e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  995 KYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLK 1073
Cdd:COG0457     2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYeEALADYEQALELDPDDAEALNN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1074 RGLFYCENENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNNWLALYYRG-CLFRKSNPF 1152
Cdd:COG0457    82 LGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGiALEKLGRYE 161


                  ....*.
gi 767982370 1153 RALQDY 1158
Cdd:COG0457   162 EALELL 167
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 901-1159 4.17e-22

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 97.49  E-value: 4.17e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  901 YVESDLPQEVIKYYESEVKILTEEINdktkypafAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQ 980
Cdd:COG2956    18 YLLNGQPDKAIDLLEEALELDPETVE--------AHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKA 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  981 DKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKV-LAIDDFSK 1059
Cdd:COG2956    90 GLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYdEAIEALEK 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1060 CIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNNWLAL 1139
Cdd:COG2956   170 ALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLL 249

                         250       260
                  ....*....|....*....|
gi 767982370 1140 YYRGCLFRKSNPFRALQDYS 1159
Cdd:COG2956   250 ALADLLERKEGLEAALALLE 269
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
933-1121 7.37e-22

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 96.23  E-value: 7.37e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  933 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYR 1012
Cdd:COG0457     8 AEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQ 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1013 GKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDF 1091
Cdd:COG0457    88 ALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYdEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELL 167

                         170       180       190
                  ....*....|....*....|....*....|
gi 767982370 1092 TALLNIDHQNSQARTYRGIAYVKWKFYKEA 1121
Cdd:COG0457   168 EKLEAAALAALLAAALGEAALALAAAEVLL 197
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 961-1150 6.00e-21

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 94.03  E-value: 6.00e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  961 LLEPLFLNAYW-HRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYF 1039
Cdd:COG2956     1 LLLPVAAALGWyFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1040 RRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFY 1118
Cdd:COG2956    81 ELAQDYLKAGLLdRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDY 160

                         170       180       190
                  ....*....|....*....|....*....|..
gi 767982370 1119 KEATQDFSAAIHLDPNNWLALYYRGCLFRKSN 1150
Cdd:COG2956   161 DEAIEALEKALKLDPDCARALLLLAELYLEQG 192
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
962-1142 8.64e-20

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 90.07  E-value: 8.64e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  962 LEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRR 1041
Cdd:COG0457     3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1042 GEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKE 1120
Cdd:COG0457    83 GLALQALGRYeEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEE 162

                         170       180
                  ....*....|....*....|..
gi 767982370 1121 ATQDFSAAIHLDPNNWLALYYR 1142
Cdd:COG0457   163 ALELLEKLEAAALAALLAAALG 184
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
1015-1158 1.01e-19

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 89.20  E-value: 1.01e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1015 KDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTA 1093
Cdd:COG4785    53 LAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYdLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDR 132

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767982370 1094 LLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNNWLALYYRGCLFRKSNPFRALQDY 1158
Cdd:COG4785   133 ALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKLDPEKALALL 197
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 933-1132 3.28e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 83.24  E-value: 3.28e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  933 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYR 1012
Cdd:COG2956    76 AEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYL 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1013 GKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDF 1091
Cdd:COG2956   156 EQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYeEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELL 235

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 767982370 1092 TALLNIDHQNSQARTYRGIaYVKWKFYKEATQDFSAAIHLD 1132
Cdd:COG2956   236 RKALELDPSDDLLLALADL-LERKEGLEAALALLERQLRRH 275
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
933-1105 1.14e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.82  E-value: 1.14e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  933 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYR 1012
Cdd:COG0457    42 AEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALL 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1013 GKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKVL-AIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDF 1091
Cdd:COG0457   122 ELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEeALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLL 201

                         170
                  ....*....|....
gi 767982370 1092 TALLNIDHQNSQAR 1105
Cdd:COG0457   202 ALEQALRKKLAILT 215
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
1028-1158 1.25e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.82  E-value: 1.25e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1028 IKSTPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQART 1106
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYeEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 767982370 1107 YRGIAYVKWKFYKEATQDFSAAIHLDPNNWLALYYRGCLFRKSNPF-RALQDY 1158
Cdd:COG0457    81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYdEAIEAY 133
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 933-1066 1.42e-14

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 71.76  E-value: 1.42e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  933 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYR 1012
Cdd:COG4783     4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767982370 1013 GKKDITLAILNYTQAIKSTPTDADIYFRRGEMY-EITNKVLAIDDFSKCIFYDPK 1066
Cdd:COG4783    84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYrALGRPDEAIAALEKALELDPD 138
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
1062-1159 6.53e-14

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 72.26  E-value: 6.53e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1062 FYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNNWLALYY 1141
Cdd:COG4785    67 LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLN 146

                          90
                  ....*....|....*....
gi 767982370 1142 RG-CLFRKSNPFRALQDYS 1159
Cdd:COG4785   147 RGiALYYLGRYELAIADLE 165
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 949-1164 1.06e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 72.33  E-value: 1.06e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  949 LQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNY---------IHKYNKNNTEAYLSKAEIYRGKKDITL 1019
Cdd:COG3914    17 LLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLalaageaaaAAAALLLLAALLELAALLLQALGRYEE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1020 AILNYTQAIKSTPTDADIYFRRGEMYEITNKVL-AIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNID 1098
Cdd:COG3914    97 ALALYRRALALNPDNAEALFNLGNLLLALGRLEeALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELD 176

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767982370 1099 HQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPN------NWLALYYRGCLFRKSNPFRALQDYSVSEPE 1164
Cdd:COG3914   177 PDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDnadahsNLLFALRQACDWEVYDRFEELLAALARGPS 248
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 919-1112 2.16e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 71.56  E-value: 2.16e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  919 KILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNK 998
Cdd:COG3914    64 AGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNP 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  999 NNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRgLF 1077
Cdd:COG3914   144 DFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLeEAIAAYRRALELDPDNADAHSNL-LF 222

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 767982370 1078 YCENENWFAAIEDFTALLNIDHQNSQARTYRGIAY 1112
Cdd:COG3914   223 ALRQACDWEVYDRFEELLAALARGPSELSPFALLY 257
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
933-1076 9.01e-12

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 66.09  E-value: 9.01e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  933 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDlnyihkynknnteaylskaeiyr 1012
Cdd:COG4785    73 AQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALED----------------------- 129

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767982370 1013 gkkditlailnYTQAIKSTPTDADIYFRRGEMYEITNK-VLAIDDFSKCIFYDPKRTDALLKRGL 1076
Cdd:COG4785   130 -----------FDRALELDPDYAYAYLNRGIALYYLGRyELAIADLEKALELDPNDPERALWLYL 183
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 1020-1135 3.09e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 61.95  E-value: 3.09e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1020 AILNYTQAIKSTPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNID 1098
Cdd:COG4235     2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYdEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 767982370 1099 HQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNN 1135
Cdd:COG4235    82 PDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 1002-1135 7.50e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 61.36  E-value: 7.50e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1002 EAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCE 1080
Cdd:COG4783     5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLdEAIVLLHEALELDPDEPEARLNLGLALLK 84

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767982370 1081 NENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNN 1135
Cdd:COG4783    85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 985-1108 3.00e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 59.25  E-value: 3.00e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  985 EALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFY 1063
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTeEAEELLERALAL 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 767982370 1064 DPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARTYR 1108
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLE 125
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 933-1140 3.02e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 64.24  E-value: 3.02e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  933 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYR 1012
Cdd:COG3914    44 ALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLL 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1013 GKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDF 1091
Cdd:COG3914   124 ALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLeEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAY 203

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 767982370 1092 TALLNIDHQNSQARTYRGIAYVK---WKFYkEATQDFSAAIHLDPNNWLALY 1140
Cdd:COG3914   204 RRALELDPDNADAHSNLLFALRQacdWEVY-DRFEELLAALARGPSELSPFA 254
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 933-1034 1.88e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 57.12  E-value: 1.88e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  933 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYR 1012
Cdd:COG4783    38 PEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYR 117

                          90       100
                  ....*....|....*....|..
gi 767982370 1013 GKKDITLAILNYTQAIKSTPTD 1034
Cdd:COG4783   118 ALGRPDEAIAALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 1034-1158 4.04e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 56.35  E-value: 4.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1034 DADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARTYRGIAY 1112
Cdd:COG4783     3 CAEALYALAQALLLAGDYdEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLAL 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 767982370 1113 VKWKFYKEATQDFSAAIHLDPNNWLALYYRGCLFRKS-NPFRALQDY 1158
Cdd:COG4783    83 LKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALgRPDEAIAAL 129
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 1053-1158 5.73e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.40  E-value: 5.73e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1053 AIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLD 1132
Cdd:COG4235     2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                          90       100
                  ....*....|....*....|....*..
gi 767982370 1133 PNNWLALYYRG-CLFRKSNPFRALQDY 1158
Cdd:COG4235    82 PDNPEALYLLGlAAFQQGDYAEAIAAW 108
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
1037-1136 1.60e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 53.25  E-value: 1.60e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1037 IYFRRGEMYEitnkvlAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEdFTALLNIDHQNSQARTYRGIAYVKWK 1116
Cdd:COG3063     1 LYLKLGDLEE------AEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELG 73

                          90       100
                  ....*....|....*....|
gi 767982370 1117 FYKEATQDFSAAIHLDPNNW 1136
Cdd:COG3063    74 DYDEALAYLERALELDPSAL 93
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 915-1135 5.18e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.40  E-value: 5.18e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370   915 ESEVKILTEEIndKTKYPAF--AYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNY 992
Cdd:TIGR02917  175 FDEARALIDEV--LTADPGNvdALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADA 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370   993 IHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRG-EMYEITNKVLAIDDFSKCIFYDPKRTDAL 1071
Cdd:TIGR02917  253 LLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGaSEYQLGNLEQAYQYLNQILKYAPNSHQAR 332

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767982370  1072 LKRGLFYCENENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNN 1135
Cdd:TIGR02917  333 RLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPEN 396
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
933-1041 7.28e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 54.54  E-value: 7.28e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  933 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYR 1012
Cdd:COG4785   107 AEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAER 186

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 767982370 1013 gKKDITLAILNYTQAIKST------PTDADIYFRR 1041
Cdd:COG4785   187 -KLDPEKALALLLEDWATAyllqgdTEEARELFKL 220
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 933-1044 8.82e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.93  E-value: 8.82e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  933 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLflNAYWHRHL--IYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEI 1010
Cdd:COG4235    17 AEGWLLLGRAYLRLGRYDEALAAYEKALRLDPD--NADALLDLaeALLAAGDTEEAEELLERALALDPDNPEALYLLGLA 94

                          90       100       110
                  ....*....|....*....|....*....|....
gi 767982370 1011 YRGKKDITLAILNYTQAIKSTPTDADIYFRRGEM 1044
Cdd:COG4235    95 AFQQGDYAEAIAAWQKLLALLPADAPARLLEASI 128
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 1002-1133 1.93e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 51.88  E-value: 1.93e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1002 EAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDAD-IYFRRGEMYEitnkvlAIDDFSKCIFYDPKRTDALLKRGLFYCE 1080
Cdd:COG5010    27 YEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDnLYNKLGDFEE------SLALLEQALQLDPNNPELYYNLALLYSR 100

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 767982370 1081 NENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDP 1133
Cdd:COG5010   101 SGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
942-1032 2.55e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 49.78  E-value: 2.55e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  942 IYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALdDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAI 1021
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                          90
                  ....*....|.
gi 767982370 1022 LNYTQAIKSTP 1032
Cdd:COG3063    80 AYLERALELDP 90
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 940-1141 2.67e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 55.09  E-value: 2.67e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370   940 GAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITL 1019
Cdd:TIGR02917  302 GASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEK 381

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  1020 AILNYTQAIKSTPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNID 1098
Cdd:TIGR02917  382 AAEYLAKATELDPENAAARTQLGISKLSQGDPsEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQ 461

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 767982370  1099 HQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNNWLALYY 1141
Cdd:TIGR02917  462 PDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAAN 504
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 901-1139 4.12e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 54.32  E-value: 4.12e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370   901 YVESDLPQEVIKYYEsEVKILTEEIndktkypAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAywHRHLI--YL 978
Cdd:TIGR02917  373 YLALGDFEKAAEYLA-KATELDPEN-------AAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRA--DLLLIlsYL 442

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370   979 FQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKV-LAIDDF 1057
Cdd:TIGR02917  443 RSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPdDAIQRF 522

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  1058 SKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEA---TQDFSAAIHLDPN 1134
Cdd:TIGR02917  523 EKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKAlaiLNEAADAAPDSPE 602


                   ....*
gi 767982370  1135 NWLAL 1139
Cdd:TIGR02917  603 AWLML 607
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 905-1032 5.41e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 50.73  E-value: 5.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  905 DLPQEVIKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKIN 984
Cdd:COG5010    26 KYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKD 105

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 767982370  985 EALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTP 1032
Cdd:COG5010   106 EAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 956-1065 1.11e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 49.57  E-value: 1.11e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  956 LQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDA 1035
Cdd:COG5010    43 AAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNP 122

                          90       100       110
                  ....*....|....*....|....*....|.
gi 767982370 1036 DIYFRRGEMYEITNKV-LAIDDFSKCIFYDP 1065
Cdd:COG5010   123 NAYSNLAALLLSLGQDdEAKAALQRALGTSP 153
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 884-1133 5.40e-06

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 50.75  E-value: 5.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370   884 EDPPERVKEPPKLKLNDYVESdLPQEVIKYYESEVKILTEEI--NDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVIL 961
Cdd:TIGR00990  281 EDSNELDEETGNGQLQLGLKS-PESKADESYEEAARAFEKALdlGKLGEKEAIALNLRGTFKCLKGKHLEALADLSKSIE 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370   962 LEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKstpTDADIYFRR 1041
Cdd:TIGR00990  360 LDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSID---LDPDFIFSH 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  1042 GEMYEITNKVLAIDD----FSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTalLNIDHQNSQARTYRGI------- 1110
Cdd:TIGR00990  437 IQLGVTQYKEGSIASsmatFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFD--TAIELEKETKPMYMNVlplinka 514

                          250       260
                   ....*....|....*....|....*
gi 767982370  1111 -AYVKWKF-YKEATQDFSAAIHLDP 1133
Cdd:TIGR00990  515 lALFQWKQdFIEAENLCEKALIIDP 539
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 1064-1154 5.83e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.65  E-value: 5.83e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1064 DPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNNWLALYYRG 1143
Cdd:COG5010    50 LAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLA 129

                          90
                  ....*....|.
gi 767982370 1144 CLFRKSNPFRA 1154
Cdd:COG5010   130 ALLLSLGQDDE 140
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 952-1074 5.86e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.92  E-value: 5.86e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  952 AMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKST 1031
Cdd:COG4235     2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 767982370 1032 PTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKR 1074
Cdd:COG4235    82 PDNPEALYLLGLAAFQQGDYaEAIAAWQKLLALLPADAPARLLE 125
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 952-1098 1.31e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.49  E-value: 1.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  952 AMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKST 1031
Cdd:COG5010     5 EGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLD 84

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767982370 1032 PTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNID 1098
Cdd:COG5010    85 PNNPELYYNLALLYSRSGDKdEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
PRK11189 PRK11189
lipoprotein NlpI; Provisional
 1014-1155 1.39e-05

lipoprotein NlpI; Provisional


Pssm-ID: 236875 [Multi-domain]  Cd Length: 296  Bit Score: 48.35  E-value: 1.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1014 KKDITLAILNytQAIKSTP-TD---ADIYFRRGEMYEitnKV----LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWF 1085
Cdd:PRK11189   41 QQEVILARLN--QILASRDlTDeerAQLHYERGVLYD---SLglraLARNDFSQALALRPDMADAYNYLGIYLTQAGNFD 115

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1086 AAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNnwlalyyrgclfrksNPFRAL 1155
Cdd:PRK11189  116 AAYEAFDSVLELDPTYNYAYLNRGIALYYGGRYELAQDDLLAFYQDDPN---------------DPYRAL 170
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
1078-1158 2.47e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.01  E-value: 2.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1078 YCENENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEAtQDFSAAIHLDPNNWLALYYRG-CLFRKSNPFRALQ 1156
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAeLLLELGDYDEALA 80


                  ..
gi 767982370 1157 DY 1158
Cdd:COG3063    81 YL 82
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 940-1155 2.99e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.54  E-value: 2.99e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370   940 GAIYRKLGKLQSAMNDLQRVILL--EPLFLNAYWHRhlIYLFQDKINEALDDL-NYIHKYNKNNTEAYLSKAEIYRGKKD 1016
Cdd:TIGR02917   63 GKIYLALGDYAAAEKELRKALSLgyPKNQVLPLLAR--AYLLQGKFQQVLDELpGKTLLDDEGAAELLALRGLAYLGLGQ 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  1017 ITLAILNYTQAIKSTPTDADI----------YFRRGEMYEITNKVLAIddfskcifyDPKRTDALLKRGLFYCENENWFA 1086
Cdd:TIGR02917  141 LELAQKSYEQALAIDPRSLYAklglaqlalaENRFDEARALIDEVLTA---------DPGNVDALLLKGDLLLSLGNIEL 211

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  1087 AIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNNWLALYYRGCL-FRKSNPFRAL 1155
Cdd:TIGR02917  212 ALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVdFQKKNYEDAR 281
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 1032-1152 3.60e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 48.06  E-value: 3.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  1032 PTDADIYFRRGEMYEITNKVL-AIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARTYRGI 1110
Cdd:TIGR00990  328 EKEAIALNLRGTFKCLKGKHLeALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQ 407

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 767982370  1111 AYVKWKFYKEATQDFSAAIHLDPNNWLALYYRGCLFRKSNPF 1152
Cdd:TIGR00990  408 LHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSI 449
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 932-1139 1.12e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.62  E-value: 1.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370   932 PAFAYCRRGAIYRKL--GKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAE 1009
Cdd:TIGR02917  156 PRSLYAKLGLAQLALaeNRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALAT 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  1010 IYRGKKDITLAILNYTQAIKSTP-------TDADIYFRRGEmYEItnkvlAIDDFSKCIFYDPKRTDALLKRGLFYCENE 1082
Cdd:TIGR02917  236 ILIEAGEFEEAEKHADALLKKAPnsplahyLKALVDFQKKN-YED-----ARETLQDALKSAPEYLPALLLAGASEYQLG 309

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 767982370  1083 NWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNNWLAL 1139
Cdd:TIGR02917  310 NLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAAL 366
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 901-1139 1.28e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.23  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370   901 YVESDLPQEVIKYYESevkilTEEINDKTKYPAFAYcrRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQ 980
Cdd:TIGR02917  100 YLLQGKFQQVLDELPG-----KTLLDDEGAAELLAL--RGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAE 172

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370   981 DKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKVLAIDdfskc 1060
Cdd:TIGR02917  173 NRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAE----- 247

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  1061 ifydpKRTDALLKR-----------GLFYCENENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAI 1129
Cdd:TIGR02917  248 -----KHADALLKKapnsplahylkALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQIL 322

                          250
                   ....*....|
gi 767982370  1130 HLDPNNWLAL 1139
Cdd:TIGR02917  323 KYAPNSHQAR 332
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 921-1155 1.30e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.23  E-value: 1.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370   921 LTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNN 1000
Cdd:TIGR02917  589 ILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDN 668

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  1001 TEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMY-EITNKVLAIDDFSKCIFYDPKrTDALLKRGLFYC 1079
Cdd:TIGR02917  669 TEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYlRQKDYPAAIQAYRKALKRAPS-SQNAIKLHRALL 747

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767982370  1080 ENENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNNWLALYYRGCLFRKSNPFRAL 1155
Cdd:TIGR02917  748 ASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKDPRAL 823
TPR_1 pfam00515
Tetratricopeptide repeat;
933-964 1.86e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 39.71  E-value: 1.86e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 767982370   933 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEP 964
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNP 32
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 866-1161 1.88e-04

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 45.75  E-value: 1.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370   866 YKDASIPVKEKDDKISVPEDppERVKEPPKLKL--NDYVESDLPQEVIKYYeSEVKILTEEindktkyPAFaYCRRGAIY 943
Cdd:TIGR00990  102 EPADELPEIDESSVANLSEE--ERKKYAAKLKEkgNKAYRNKDFNKAIKLY-SKAIECKPD-------PVY-YSNRAACH 170

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370   944 RKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLN---YIHKYNKNNTEAYL---------SKA-EI 1010
Cdd:TIGR00990  171 NALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLGKYADALLDLTascIIDGFRNEQSAQAVerllkkfaeSKAkEI 250

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  1011 YRGKKD---ITLAILNYTQAIKSTPTDA-----------------DIYFRRGEMYEITNKVLAIDDFSKCIFYD---PKR 1067
Cdd:TIGR00990  251 LETKPEnlpSVTFVGNYLQSFRPKPRPAgledsneldeetgngqlQLGLKSPESKADESYEEAARAFEKALDLGklgEKE 330

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370  1068 TDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARTYRGIAYVKWKFYKEATQDFSAAIHLDPNNWLALYYRGCL-F 1146
Cdd:TIGR00990  331 AIALNLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLhF 410

                          330
                   ....*....|....*
gi 767982370  1147 RKSNPFRALQDYSVS 1161
Cdd:TIGR00990  411 IKGEFAQAGKDYQKS 425
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
1010-1098 2.50e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 41.31  E-value: 2.50e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767982370 1010 IYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIE 1089
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEKALKLDPNNAEALLNLAELLLELGDYDEALA 80


                  ....*....
gi 767982370 1090 DFTALLNID 1098
Cdd:COG3063    81 YLERALELD 89
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 933-964 6.25e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 38.20  E-value: 6.25e-04
                            10        20        30
                    ....*....|....*....|....*....|..
gi 767982370    933 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEP 964
Cdd:smart00028    1 AEALYNLGNAYLKLGDYDEALEYYEKALELDP 32
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
933-991 1.51e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.00  E-value: 1.51e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767982370  933 AFAYCRRGAIYRKLGKLQSAMnDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLN 991
Cdd:COG3063    26 ADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLE 83
TPR_11 pfam13414
TPR repeat;
1010-1046 2.36e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.68  E-value: 2.36e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 767982370  1010 IYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYE 1046
Cdd:pfam13414    3 AYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYY 39
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 933-964 8.03e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 35.19  E-value: 8.03e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 767982370   933 AFAYCRRGAIYRKLGKLQSAMNDLQRVILLEP 964
Cdd:pfam07719    1 AEALYNLGLAYYKLGDYEEALEAYEKALELDP 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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