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Conserved domains on  [gi|767977880|ref|XP_011533451|]
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centromere protein J isoform X2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 898-1079 1.42e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 1.42e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   898 GDNARSQVL---REKIIELETEIEKFKAENAS----LAKLRIER---ESALEKLRKEIADFEQQKAKELARIEEFKKE-- 965
Cdd:TIGR02168  664 GSAKTNSSIlerRREIEELEEKIEELEEKIAElekaLAELRKELeelEEELEQLRKELEELSRQISALRKDLARLEAEve 743

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   966 ----EMRKLQKERKVFEKYTTAART-----FPDKKERE-EIQTLKQQIADLREDLKrketKWSSTHSRLRSQIQMLVREN 1035
Cdd:TIGR02168  744 qleeRIAQLSKELTELEAEIEELEErleeaEEELAEAEaEIEELEAQIEQLKEELK----ALREALDELRAELTLLNEEA 819

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 767977880  1036 TDLREEIKVMERFRLDAWKRAEAIESSLEVEKKDKLANTSVRFQ 1079
Cdd:TIGR02168  820 ANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEE 863
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 898-1079 1.42e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 1.42e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   898 GDNARSQVL---REKIIELETEIEKFKAENAS----LAKLRIER---ESALEKLRKEIADFEQQKAKELARIEEFKKE-- 965
Cdd:TIGR02168  664 GSAKTNSSIlerRREIEELEEKIEELEEKIAElekaLAELRKELeelEEELEQLRKELEELSRQISALRKDLARLEAEve 743

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   966 ----EMRKLQKERKVFEKYTTAART-----FPDKKERE-EIQTLKQQIADLREDLKrketKWSSTHSRLRSQIQMLVREN 1035
Cdd:TIGR02168  744 qleeRIAQLSKELTELEAEIEELEErleeaEEELAEAEaEIEELEAQIEQLKEELK----ALREALDELRAELTLLNEEA 819

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 767977880  1036 TDLREEIKVMERFRLDAWKRAEAIESSLEVEKKDKLANTSVRFQ 1079
Cdd:TIGR02168  820 ANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEE 863
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
901-1058 4.09e-08

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 57.56  E-value: 4.09e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  901 ARSQVLREKIIELETEIEKFKAENASLaklrierESALEKLRKEIADFEqqkakelARIEEFKKEEMRKLQKERKVfeky 980
Cdd:COG2433   406 RELTEEEEEIRRLEEQVERLEAEVEEL-------EAELEEKDERIERLE-------RELSEARSEERREIRKDREI---- 467

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767977880  981 ttaartfpdKKEREEIQTLKQQIADLREDLKRKETKWssthSRLRSQIQMLVRENTdlrEEIKVMERFRLDAWKRAEA 1058
Cdd:COG2433   468 ---------SRLDREIERLERELEEERERIEELKRKL----ERLKELWKLEHSGEL---VPVKVVEKFTKEAIRRLEE 529
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
906-1072 1.30e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.68  E-value: 1.30e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  906 LREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEqQKAKELARIEEfKKEEMRKLQKERkvfEKYTTAAR 985
Cdd:PRK03918  236 LKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELE-EKVKELKELKE-KAEEYIKLSEFY---EEYLDELR 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  986 TFPDKKER--EEIQTLKQQIADLREDLKRKEtkwssthsRLRSQIQMLVRENTDLREEIKVMERFR-----LDAWKRAEA 1058
Cdd:PRK03918  311 EIEKRLSRleEEINGIEERIKELEEKEERLE--------ELKKKLKELEKRLEELEERHELYEEAKakkeeLERLKKRLT 382

                         170
                  ....*....|....
gi 767977880 1059 IESSLEVEKKDKLA 1072
Cdd:PRK03918  383 GLTPEKLEKELEEL 396
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 901-1113 5.84e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.96  E-value: 5.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   901 ARSQVLRE-----KIIELETEIEKFKAENAS-----LAKLRIERESALEKLRKEiaDFEQQKAKELARIEEF----KKEE 966
Cdd:pfam17380  401 ARKVKILEeerqrKIQQQKVEMEQIRAEQEEarqreVRRLEEERAREMERVRLE--EQERQQQVERLRQQEEerkrKKLE 478

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   967 MRKLQKE--------RKVFEKYTTAARTFPDKKER------EEIQTLKQQIADLREDLKRKETKWSSTHSRLRSQIQMLV 1032
Cdd:pfam17380  479 LEKEKRDrkraeeqrRKILEKELEERKQAMIEEERkrklleKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQM 558

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  1033 RENTDLREEIKVMERFRldawkraEAIESSLEVEKKDKlantsvrfqnsQISSGTQVEKYKKNYLPMQGTAQPPHTPSSL 1112
Cdd:pfam17380  559 RKATEERSRLEAMERER-------EMMRQIVESEKARA-----------EYEATTPITTIKPIYRPRISEYQPPDVESHM 620


                   .
gi 767977880  1113 L 1113
Cdd:pfam17380  621 I 621
alph_xenorhab_B NF033927
alpha-xenorhabdolysin family binary toxin subunit B;
912-1062 2.04e-03

alpha-xenorhabdolysin family binary toxin subunit B;


Pssm-ID: 411488 [Multi-domain]  Cd Length: 223  Bit Score: 41.08  E-value: 2.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  912 ELETEIEKFKAENASLAKLRIERESA--LEKLRKEIADFEQQKAKELARIEEFKkEEMRKLQKERKVFEKYTTAAR---T 986
Cdd:NF033927    8 ALRKSAAKIANKLDDLSQINLREATLdlLAQLQEQIAELEAQIAALESKLNELA-EDRKVIIEAIDLIEKYNIADLfkdL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  987 FPDKKE-------REEIQTLKQQIadlrEDLKRKETKWSS-------THSR--LRSQIQMLVRENTDLREEIKVMErFRL 1050
Cdd:NF033927   87 LPTAEEidslglpPPEKDLVKAAI----ERLKKLLGKISEgltyidlVEARdkLRDRINALLAESRTLDKDIKALA-GKL 161

                         170
                  ....*....|..
gi 767977880 1051 DAWKRAEAIESS 1062
Cdd:NF033927  162 EELTAIAAIDEE 173
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 898-1079 1.42e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 1.42e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   898 GDNARSQVL---REKIIELETEIEKFKAENAS----LAKLRIER---ESALEKLRKEIADFEQQKAKELARIEEFKKE-- 965
Cdd:TIGR02168  664 GSAKTNSSIlerRREIEELEEKIEELEEKIAElekaLAELRKELeelEEELEQLRKELEELSRQISALRKDLARLEAEve 743

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   966 ----EMRKLQKERKVFEKYTTAART-----FPDKKERE-EIQTLKQQIADLREDLKrketKWSSTHSRLRSQIQMLVREN 1035
Cdd:TIGR02168  744 qleeRIAQLSKELTELEAEIEELEErleeaEEELAEAEaEIEELEAQIEQLKEELK----ALREALDELRAELTLLNEEA 819

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 767977880  1036 TDLREEIKVMERFRLDAWKRAEAIESSLEVEKKDKLANTSVRFQ 1079
Cdd:TIGR02168  820 ANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEE 863
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
901-1058 4.09e-08

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 57.56  E-value: 4.09e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  901 ARSQVLREKIIELETEIEKFKAENASLaklrierESALEKLRKEIADFEqqkakelARIEEFKKEEMRKLQKERKVfeky 980
Cdd:COG2433   406 RELTEEEEEIRRLEEQVERLEAEVEEL-------EAELEEKDERIERLE-------RELSEARSEERREIRKDREI---- 467

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767977880  981 ttaartfpdKKEREEIQTLKQQIADLREDLKRKETKWssthSRLRSQIQMLVRENTdlrEEIKVMERFRLDAWKRAEA 1058
Cdd:COG2433   468 ---------SRLDREIERLERELEEERERIEELKRKL----ERLKELWKLEHSGEL---VPVKVVEKFTKEAIRRLEE 529
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
902-1047 5.69e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 5.69e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  902 RSQVLREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIAdfeQQKAKELARIEEFKKEEMRKLQKERKVFEKYT 981
Cdd:COG4913   289 RLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIR---GNGGDRLEQLEREIERLERELEERERRRARLE 365

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767977880  982 TAART--FPDKKEREEIQTLKQQIADLREDLKRKETKWSSTHSRLRSQIQMLVRENTDLREEIKVMER 1047
Cdd:COG4913   366 ALLAAlgLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLER 433
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 886-1080 6.55e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.00  E-value: 6.55e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   886 ELKLNISQDQPPGDNARSQVLREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKAKElaRIEEfKKE 965
Cdd:TIGR02169  722 EKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHS--RIPE-IQA 798

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   966 EMRKLQKERKVFEKYT------TAARTFPDKKEREEIQTLKQQIADLR----------EDLKRKETKWSSTHSRLRSQIQ 1029
Cdd:TIGR02169  799 ELSKLEEEVSRIEARLreieqkLNRLTLEKEYLEKEIQELQEQRIDLKeqiksiekeiENLNGKKEELEEELEELEAALR 878

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 767977880  1030 MLVRENTDLREEIKVMERFRLDAWKRAEAIESSLEvEKKDKLANTSVRFQN 1080
Cdd:TIGR02169  879 DLESRLGDLKKERDELEAQLRELERKIEELEAQIE-KKRKRLSELKAKLEA 928
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 900-1073 1.00e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.48  E-value: 1.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  900 NARSQVLREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKAKELARIEEFKKEEMRKLQKERkvfEK 979
Cdd:COG1196   238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR---EL 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  980 YTTAARtfpdkkEREEIQTLKQQIADLREDLKRKETKWSSTHSRLRSQIQMLVRENTDLREEIKVMERfRLDAWKRAEAI 1059
Cdd:COG1196   315 EERLEE------LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE-AEEELEELAEE 387

                         170
                  ....*....|....
gi 767977880 1060 ESSLEVEKKDKLAN 1073
Cdd:COG1196   388 LLEALRAAAELAAQ 401
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 900-1083 1.49e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 1.49e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  900 NARSQVLREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKAKELARIEEFKKEEMRKLQKERKVFEK 979
Cdd:COG1196   287 QAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  980 YTTAARTFPDKKE-----REEIQTLKQQIADLREDLKRKETKWSSTHSRLRSQIQMLVRENTDLREEIKVMERFRLDAWK 1054
Cdd:COG1196   367 LLEAEAELAEAEEeleelAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                         170       180
                  ....*....|....*....|....*....
gi 767977880 1055 RAEAIESSLEVEKKDKLANTSVRFQNSQI 1083
Cdd:COG1196   447 AAEEEAELEEEEEALLELLAELLEEAALL 475
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 900-1072 3.18e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.94  E-value: 3.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  900 NARSQVLREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKAKELARIEEFKKEEMRKlqkerkvfek 979
Cdd:COG1196   280 ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEA---------- 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  980 yttaartfpdKKEREEIQTLKQQIADLREDLKRKETKWSSTHSRLRSQIQMLVRENTDLREEIKVMERFRLDAWKRAEAI 1059
Cdd:COG1196   350 ----------EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL 419

                         170
                  ....*....|...
gi 767977880 1060 ESSLEVEKKDKLA 1072
Cdd:COG1196   420 EEELEELEEALAE 432
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
883-1072 6.46e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 53.62  E-value: 6.46e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  883 LGNELK--LNISQDQPPGDNARSQVLREKIIELETEIEKFKAENASLAKLRIERESA---LEKLRKEIADFEQQKA---- 953
Cdd:COG4717    51 LEKEADelFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELeaeLEELREELEKLEKLLQllpl 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  954 -KELARIEEFKKEEMRKLQKERKVFEKYTTAartfpdkkeREEIQTLKQQIADLREDLKRKETKWSSTHsrlRSQIQMLV 1032
Cdd:COG4717   131 yQELEALEAELAELPERLEELEERLEELREL---------EEELEELEAELAELQEELEELLEQLSLAT---EEELQDLA 198

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 767977880 1033 RENTDLREEIKVMERFRLDAWKRAEAIESSLEVEKKDKLA 1072
Cdd:COG4717   199 EELEELQQRLAELEEELEEAQEELEELEEELEQLENELEA 238
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 906-1046 2.82e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.92  E-value: 2.82e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  906 LREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKAKELARIEEFKK--------EEMRKLQKErkvf 977
Cdd:COG1579    22 LEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEqlgnvrnnKEYEALQKE---- 97

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767977880  978 EKYTTAARTFPDKKERE---EIQTLKQQIADLREDLKRKETKWSSTHSRLRSQIQMLVRENTDLREEIKVME 1046
Cdd:COG1579    98 IESLKRRISDLEDEILElmeRIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELA 169
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 906-1042 2.84e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.92  E-value: 2.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  906 LREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQ-----KAKELARIEefkkEEMRKLQKERKVFEKY 980
Cdd:COG1579    36 LEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQlgnvrNNKEYEALQ----KEIESLKRRISDLEDE 111

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767977880  981 TTAARTFPDKKErEEIQTLKQQIADLREDLKRKETKWSSTHSRLRSQIQMLVRENTDLREEI 1042
Cdd:COG1579   112 ILELMERIEELE-EELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKI 172
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 901-1047 3.40e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.60  E-value: 3.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   901 ARSQVLREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKAKELARIEEFkKEEMRKLQKERKVFEKY 980
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERL-EARLERLEDRRERLQQE 422

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767977880   981 TTAARTFPDKKEREEIQ----TLKQQIADLREDLKRKETKWSSTHSRLR---SQIQMLVRENTDLREEIKVMER 1047
Cdd:TIGR02168  423 IEELLKKLEEAELKELQaeleELEEELEELQEELERLEEALEELREELEeaeQALDAAERELAQLQARLDSLER 496
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
900-1079 4.31e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.79  E-value: 4.31e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  900 NARSQVLREKIIELETEIEKFKAENASLAkLRIERESALEKLrkeiADFEQQKAKELARIEEfKKEEMRKLQKERKvfek 979
Cdd:COG3206   181 EEQLPELRKELEEAEAALEEFRQKNGLVD-LSEEAKLLLQQL----SELESQLAEARAELAE-AEARLAALRAQLG---- 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  980 ytTAARTFPDKKEREEIQTLKQQIADLREDLKRKETKWSSTHS---RLRSQIQMLVRENTDLREEIKVMERFRLDAWK-R 1055
Cdd:COG3206   251 --SGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPdviALRAQIAALRAQLQQEAQRILASLEAELEALQaR 328

                         170       180
                  ....*....|....*....|....*.
gi 767977880 1056 AEAIESSLEVEKK--DKLANTSVRFQ 1079
Cdd:COG3206   329 EASLQAQLAQLEArlAELPELEAELR 354
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 906-1064 4.42e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.21  E-value: 4.42e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   906 LREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKakelarieEFKKEEMRKLQKERKVFEKYTTAAR 985
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQK--------QILRERLANLERQLEELEAQLEELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   986 TFPDKKE------REEIQTLKQQIADLREDLKRKETKWSSTHSR---LRSQIQMLVRENTDLREEIKVMERFRLDAWKRA 1056
Cdd:TIGR02168  330 SKLDELAeelaelEEKLEELKEELESLEAELEELEAELEELESRleeLEEQLETLRSKVAQLELQIASLNNEIERLEARL 409


                   ....*...
gi 767977880  1057 EAIESSLE 1064
Cdd:TIGR02168  410 ERLEDRRE 417
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 900-1074 6.98e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.44  E-value: 6.98e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   900 NARSQVLREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKAKELARIEEFKKEEMRKLQKERKVFEK 979
Cdd:TIGR02168  301 EQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   980 YTTAARtfpdkkereEIQTLKQQIADLREDLkrketkwssthSRLRSQIQMLVRENTDLREEIkvmeRFRLDAWKRAEAI 1059
Cdd:TIGR02168  381 LETLRS---------KVAQLELQIASLNNEI-----------ERLEARLERLEDRRERLQQEI----EELLKKLEEAELK 436

                          170
                   ....*....|....*
gi 767977880  1060 ESSLEVEKKDKLANT 1074
Cdd:TIGR02168  437 ELQAELEELEEELEE 451
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
906-1072 1.30e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.68  E-value: 1.30e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  906 LREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEqQKAKELARIEEfKKEEMRKLQKERkvfEKYTTAAR 985
Cdd:PRK03918  236 LKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELE-EKVKELKELKE-KAEEYIKLSEFY---EEYLDELR 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  986 TFPDKKER--EEIQTLKQQIADLREDLKRKEtkwssthsRLRSQIQMLVRENTDLREEIKVMERFR-----LDAWKRAEA 1058
Cdd:PRK03918  311 EIEKRLSRleEEINGIEERIKELEEKEERLE--------ELKKKLKELEKRLEELEERHELYEEAKakkeeLERLKKRLT 382

                         170
                  ....*....|....
gi 767977880 1059 IESSLEVEKKDKLA 1072
Cdd:PRK03918  383 GLTPEKLEKELEEL 396
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 888-1028 1.58e-05

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 49.31  E-value: 1.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  888 KLNISQDQPPgdnARSQVLREKIIELETEIEKFKAENASLAKLRieresaLEKLRKEIADFEQQKAKELARIEEfKKEEM 967
Cdd:COG0542   401 RVRMEIDSKP---EELDELERRLEQLEIEKEALKKEQDEASFER------LAELRDELAELEEELEALKARWEA-EKELI 470

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767977880  968 RKLQkerkvfekyttaartfpdkKEREEIQTLKQQIADLREDLKRKETKWSSTHSRLRSQI 1028
Cdd:COG0542   471 EEIQ-------------------ELKEELEQRYGKIPELEKELAELEEELAELAPLLREEV 512
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
898-1060 1.64e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 1.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  898 GDNARSQV--LREKIIELETEIEKFKAENASLAKLR---IERESALEKLRKeiADFEQQKAKELAR-IEEfKKEEMRKLQ 971
Cdd:COG4913   605 GFDNRAKLaaLEAELAELEEELAEAEERLEALEAELdalQERREALQRLAE--YSWDEIDVASAEReIAE-LEAELERLD 681

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  972 KERKVFEKYTTAArtfpdKKEREEIQTLKQQIADLREDLKRKETKWSsthsRLRSQIQMLVRENTDLREEIKVMERFRLD 1051
Cdd:COG4913   682 ASSDDLAALEEQL-----EELEAELEELEEELDELKGEIGRLEKELE----QAEEELDELQDRLEAAEDLARLELRALLE 752


                  ....*....
gi 767977880 1052 AWKRAEAIE 1060
Cdd:COG4913   753 ERFAAALGD 761
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 885-1027 2.13e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 2.13e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  885 NELKLNISQDQPPGDNARSQVLREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKaKELARIEEFKK 964
Cdd:COG4942   120 PPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEER-AALEALKAERQ 198

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767977880  965 EEMRKLQKERkvfekyttaartfpdKKEREEIQTLKQQIADLREDLKRKETKWSSTHSRLRSQ 1027
Cdd:COG4942   199 KLLARLEKEL---------------AELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 878-1064 2.48e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.53  E-value: 2.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   878 KSDSHLGNELKLNISQDQPPGDNARSQVLREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEqqkaKELA 957
Cdd:TIGR02169  651 KSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE----KEIE 726

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   958 RIEEfKKEEMRKLQKERKVFEKYTTAARTfpdkKEREEIQTLKQQIADLREDLKRKETKWSSTHSRL-RSQIQMLVRENT 1036
Cdd:TIGR02169  727 QLEQ-EEEKLKERLEELEEDLSSLEQEIE----NVKSELKELEARIEELEEDLHKLEEALNDLEARLsHSRIPEIQAELS 801

                          170       180
                   ....*....|....*....|....*...
gi 767977880  1037 DLREEIKVMErfrldawKRAEAIESSLE 1064
Cdd:TIGR02169  802 KLEEEVSRIE-------ARLREIEQKLN 822
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
923-1064 6.40e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.34  E-value: 6.40e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  923 ENASLAKLRIER-----ESALEKLRKEIADFEQ-----------QKAKEL-ARIEEFkkEEMRKLQKERKvfekyTTAAR 985
Cdd:PRK02224  169 ERASDARLGVERvlsdqRGSLDQLKAQIEEKEEkdlherlngleSELAELdEEIERY--EEQREQARETR-----DEADE 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  986 TFPDKKE-REEIQTLKQQIADLREDLKRKETKWSSTHSR---LRSQIQMLVRENTDLREE-------IKVMERFRLDAWK 1054
Cdd:PRK02224  242 VLEEHEErREELETLEAEIEDLRETIAETEREREELAEEvrdLRERLEELEEERDDLLAEaglddadAEAVEARREELED 321

                         170
                  ....*....|
gi 767977880 1055 RAEAIESSLE 1064
Cdd:PRK02224  322 RDEELRDRLE 331
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 912-1072 7.75e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.85  E-value: 7.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  912 ELETEIEKFKAEnASLAKLRiERESALEKLRKEIADFEQQKAKELARIEEF--KKEEMR-KLQKERKVFEKYTTAARtfp 988
Cdd:COG1196   217 ELKEELKELEAE-LLLLKLR-ELEAELEELEAELEELEAELEELEAELAELeaELEELRlELEELELELEEAQAEEY--- 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  989 dkKEREEIQTLKQQIADLREDLKRKEtkwsSTHSRLRSQIQMLVRENTDLREEIKVMERFRLDAWKRAEAIESSLEVEKK 1068
Cdd:COG1196   292 --ELLAELARLEQDIARLEERRRELE----ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE 365


                  ....
gi 767977880 1069 DKLA 1072
Cdd:COG1196   366 ALLE 369
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
907-1077 8.54e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.96  E-value: 8.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  907 REKIIELETEIEKFKAENASLAKlRIERESALEKLRKEIADFEQQKAKELARIEEFK---KEEMRKLQKERKVFEKYTTA 983
Cdd:PRK02224  474 RERVEELEAELEDLEEEVEEVEE-RLERAEDLVEAEDRIERLEERREDLEELIAERRetiEEKRERAEELRERAAELEAE 552

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  984 ARTfpdkkEREEIQTLKQQIADLREDLKRKETKWSSTHSRLRS--QIQMLVRENTDLREEIkvmERFRLdawKRAEAIEs 1061
Cdd:PRK02224  553 AEE-----KREAAAEAEEEAEEAREEVAELNSKLAELKERIESleRIRTLLAAIADAEDEI---ERLRE---KREALAE- 620

                         170
                  ....*....|....*.
gi 767977880 1062 sLEVEKKDKLANTSVR 1077
Cdd:PRK02224  621 -LNDERRERLAEKRER 635
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
901-1032 1.67e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 1.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  901 ARSQVLREKIIELETEIEKFKAENASLAklriERESALEKLRKEIADFEQQKAKELARIEEFKKEEMRKLQKERKVFEKY 980
Cdd:COG4717   132 QELEALEAELAELPERLEELEERLEELR----ELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQR 207

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 767977880  981 TTAArtfpdkkeREEIQTLKQQIADLREDLKRKETKWSSTH--SRLRSQIQMLV 1032
Cdd:COG4717   208 LAEL--------EEELEEAQEELEELEEELEQLENELEAAAleERLKEARLLLL 253
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 912-1071 2.02e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.83  E-value: 2.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   912 ELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKAKELARIEEFKKEEMRKLQKE-RKVFEKYTTAARTFPDK 990
Cdd:TIGR02169  234 ALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKiGELEAEIASLERSIAEK 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   991 KerEEIQTLKQQIADLREDLKRKEtkwsSTHSRLRSQIQMLVRENTDLREEIKVMERFRLDAWKRAEAI---------ES 1061
Cdd:TIGR02169  314 E--RELEDAEERLAKLEAEIDKLL----AEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVdkefaetrdEL 387

                          170
                   ....*....|
gi 767977880  1062 SLEVEKKDKL 1071
Cdd:TIGR02169  388 KDYREKLEKL 397
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 900-1062 2.59e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.82  E-value: 2.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  900 NARSQVLREKIIELETEIEKFKAEnasLAKLRIERESALEKLRKEIADFEQQ---------------------KAKELAR 958
Cdd:COG3883    50 NEEYNELQAELEALQAEIDKLQAE---IAEAEAEIEERREELGERARALYRSggsvsyldvllgsesfsdfldRLSALSK 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  959 IEEFKKEEMRKLQKERKVFEKYTTAArtfpdKKEREEIQTLKQQIADLREDLKRKETKWSSTHSRLRSQIQMLVRENTDL 1038
Cdd:COG3883   127 IADADADLLEELKADKAELEAKKAEL-----EAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAEL 201

                         170       180
                  ....*....|....*....|....
gi 767977880 1039 REEIKVMERFRLDAWKRAEAIESS 1062
Cdd:COG3883   202 EAELAAAEAAAAAAAAAAAAAAAA 225
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 900-1064 3.56e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 3.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  900 NARSQVLREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADF--EQQKAKELARIEE-FKKEEMRKLQKERKV 976
Cdd:COG4942    61 ERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELlrALYRLGRQPPLALlLSPEDFLDAVRRLQY 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  977 FEKYTTAARTFPD--KKEREEIQTLKQQIADLREDLKRKETKWSSTHSRLRSQIQMLVRENTDLREEIKVMERFRLDAWK 1054
Cdd:COG4942   141 LKYLAPARREQAEelRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQ 220

                         170
                  ....*....|
gi 767977880 1055 RAEAIESSLE 1064
Cdd:COG4942   221 EAEELEALIA 230
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
906-1069 4.32e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.67  E-value: 4.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  906 LREKIIELETEIEKFKAENASLAKLrierESALEKLRKEIADFEQQKAKELARIEEFK----KEEMRKLQKERKVFEKYT 981
Cdd:PRK03918  530 LKEKLIKLKGEIKSLKKELEKLEEL----KKKLAELEKKLDELEEELAELLKELEELGfesvEELEERLKELEPFYNEYL 605

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  982 TAartfpdKKEREEIQTLKQQIADLREDLKRKETKWSSTHSR---LRSQIQMLVRENTD-----LREEI--KVMERFRLD 1051
Cdd:PRK03918  606 EL------KDAEKELEREEKELKKLEEELDKAFEELAETEKRleeLRKELEELEKKYSEeeyeeLREEYleLSRELAGLR 679

                         170
                  ....*....|....*...
gi 767977880 1052 AwkRAEAIESSLEVEKKD 1069
Cdd:PRK03918  680 A--ELEELEKRREEIKKT 695
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 901-1113 5.84e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.96  E-value: 5.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   901 ARSQVLRE-----KIIELETEIEKFKAENAS-----LAKLRIERESALEKLRKEiaDFEQQKAKELARIEEF----KKEE 966
Cdd:pfam17380  401 ARKVKILEeerqrKIQQQKVEMEQIRAEQEEarqreVRRLEEERAREMERVRLE--EQERQQQVERLRQQEEerkrKKLE 478

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   967 MRKLQKE--------RKVFEKYTTAARTFPDKKER------EEIQTLKQQIADLREDLKRKETKWSSTHSRLRSQIQMLV 1032
Cdd:pfam17380  479 LEKEKRDrkraeeqrRKILEKELEERKQAMIEEERkrklleKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQM 558

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  1033 RENTDLREEIKVMERFRldawkraEAIESSLEVEKKDKlantsvrfqnsQISSGTQVEKYKKNYLPMQGTAQPPHTPSSL 1112
Cdd:pfam17380  559 RKATEERSRLEAMERER-------EMMRQIVESEKARA-----------EYEATTPITTIKPIYRPRISEYQPPDVESHM 620


                   .
gi 767977880  1113 L 1113
Cdd:pfam17380  621 I 621
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
935-1073 6.14e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 6.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  935 ESALEKLRKEIADFEQQKAKELARIEEFKkEEMRKLQKERKVFEKYTTAARTFPDKKE-REEIQTLKQQIADLREDlkrk 1013
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALE-AELDALQERREALQRLAEYSWDEIDVASaEREIAELEAELERLDAS---- 683

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880 1014 etkwSSTHSRLRSQIQMLVRENTDLREEIKVMERFRLDAWKRAEAIESSLEvEKKDKLAN 1073
Cdd:COG4913   684 ----SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELD-ELQDRLEA 738
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 906-1064 6.79e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.90  E-value: 6.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   906 LREKIIELETEIEKFKAENASLAKL------RIERESALEKLR--KEIADFEQQKAKeLARIEEFKKEEMRKLQKER--- 974
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLleelnkKIKDLGEEEQLRvkEKIGELEAEIAS-LERSIAEKERELEDAEERLakl 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   975 -----KVFEKYTTAARTFPDKKER-----EEIQTLKQQIADLREDLKRKETKwsstHSRLRSQIQMLVRENTDLREEIKV 1044
Cdd:TIGR02169  328 eaeidKLLAEIEELEREIEEERKRrdkltEEYAELKEELEDLRAELEEVDKE----FAETRDELKDYREKLEKLKREINE 403

                          170       180
                   ....*....|....*....|
gi 767977880  1045 MERFRLDAWKRAEAIESSLE 1064
Cdd:TIGR02169  404 LKRELDRLQEELQRLSEELA 423
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
904-1064 6.84e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 6.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  904 QVLREKIIELETEIEKFKAENASLAKLRIER-ESALEKLRKEIADFeQQKAKELARIEEfKKEEMRKLQKE-RKVFEKYT 981
Cdd:COG4717    45 AMLLERLEKEADELFKPQGRKPELNLKELKElEEELKEAEEKEEEY-AELQEELEELEE-ELEELEAELEElREELEKLE 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  982 TAARTFPDKKEREEIQTLKQQIADLREDLKRKETKWssthSRLRSQIQMLVRENTDLREEI-KVMERFRLDAWKRAEAIE 1060
Cdd:COG4717   123 KLLQLLPLYQELEALEAELAELPERLEELEERLEEL----RELEEELEELEAELAELQEELeELLEQLSLATEEELQDLA 198


                  ....
gi 767977880 1061 SSLE 1064
Cdd:COG4717   199 EELE 202
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
901-1070 6.95e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.90  E-value: 6.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  901 ARSQVLREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKAKelarIEEFKKEEMRKLQKERKVFEKy 980
Cdd:PRK03918  186 KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEE----IEELEKELESLEGSKRKLEEK- 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  981 ttaartfpdKKEREE-IQTLKQQIADLREDLKR-KETKWSST--------HSRLRSQIQMLVRENTDLREEIKVMERFRL 1050
Cdd:PRK03918  261 ---------IRELEErIEELKKEIEELEEKVKElKELKEKAEeyiklsefYEEYLDELREIEKRLSRLEEEINGIEERIK 331

                         170       180
                  ....*....|....*....|
gi 767977880 1051 DAWKRAEAIEsslEVEKKDK 1070
Cdd:PRK03918  332 ELEEKEERLE---ELKKKLK 348
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 906-1069 7.65e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 7.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  906 LREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKAKELARIEEFKKEE---MRKLQKERKVFEK--- 979
Cdd:COG4942    32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIaelRAELEAQKEELAEllr 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  980 --YTTAARTFP-------------------------DKKEREEIQTLKQQIADLREDLKRKetkwsstHSRLRSQIQMLV 1032
Cdd:COG4942   112 alYRLGRQPPLalllspedfldavrrlqylkylapaRREQAEELRADLAELAALRAELEAE-------RAELEALLAELE 184

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 767977880 1033 RENTDLREEIKVMERFRLDAWKRAEAIESSLEVEKKD 1069
Cdd:COG4942   185 EERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 906-1043 1.10e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.13  E-value: 1.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   906 LREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKAKELARIEEfKKEEMRKLQKERKvfekyTTAAR 985
Cdd:TIGR02169  390 YREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKED-KALEIKKQEWKLE-----QLAAD 463

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 767977880   986 TfpdKKEREEIQTLKQQIADLREDLKRKETKWSSTHSRlRSQIQMLVRENTDLREEIK 1043
Cdd:TIGR02169  464 L---SKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQ-ARASEERVRGGRAVEEVLK 517
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 928-1069 1.25e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.15  E-value: 1.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  928 AKLRIERES---ALEKLRKEIADFEQQKakelariEEFKKEEmrklqkerkvfekyttaartfpDKKEREEIQTLKQQIA 1004
Cdd:COG0542   400 ARVRMEIDSkpeELDELERRLEQLEIEK-------EALKKEQ----------------------DEASFERLAELRDELA 450

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767977880 1005 DLREDLKRKETKWSSTHSRLrSQIQMLVRENTDLREEIKVMERFRLDAWKRAEAIESSL--EVEKKD 1069
Cdd:COG0542   451 ELEEELEALKARWEAEKELI-EEIQELKEELEQRYGKIPELEKELAELEEELAELAPLLreEVTEED 516
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
906-1064 1.30e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 43.11  E-value: 1.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  906 LREKIIELETEIEKFK------AENASLAKLRI----ERESALEKLRKEIADFEQQKAKELARIEEFKkEEMRKLQKERK 975
Cdd:PRK02224  211 LESELAELDEEIERYEeqreqaRETRDEADEVLeeheERREELETLEAEIEDLRETIAETEREREELA-EEVRDLRERLE 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  976 VFEKYTTAARtfpDKKEREEIQtlKQQIADLREDLKRKETKWSSTHSRLRSQIQMLVRENTDLREEIKVMERFRLDAWKR 1055
Cdd:PRK02224  290 ELEEERDDLL---AEAGLDDAD--AEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREE 364


                  ....*....
gi 767977880 1056 AEAIESSLE 1064
Cdd:PRK02224  365 AAELESELE 373
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 900-993 1.39e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 1.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  900 NARSQVLREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADfEQQKAKELARIEEFKKEEMRKLQKERKVFEK 979
Cdd:COG4942   163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAE-LAAELAELQQEAEELEALIARLEAEAAAAAE 241

                          90
                  ....*....|....
gi 767977880  980 yTTAARTFPDKKER 993
Cdd:COG4942   242 -RTPAAGFAALKGK 254
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 925-1033 1.74e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 1.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  925 ASLAKLRIERESALEKLRKEIadfeQQKAKELARIeefkKEEMRKLQKERKVFEKYTTAArtfpdkkeREEIQTLKQQIA 1004
Cdd:COG4942    16 AAQADAAAEAEAELEQLQQEI----AELEKELAAL----KKEEKALLKQLAALERRIAAL--------ARRIRALEQELA 79

                          90       100
                  ....*....|....*....|....*....
gi 767977880 1005 DLREDLKRKETKWSSTHSRLRSQIQMLVR 1033
Cdd:COG4942    80 ALEAELAELEKEIAELRAELEAQKEELAE 108
PTZ00121 PTZ00121
MAEBL; Provisional
 908-1073 1.91e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 1.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  908 EKIIELETEIEKFKAENASLA---KLRIERESALEKLRKEIADFEQQKAKELARIEEFKKEE----MRKLQKERKVFEky 980
Cdd:PTZ00121 1595 EEVMKLYEEEKKMKAEEAKKAeeaKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEeenkIKAAEEAKKAEE-- 1672

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  981 ttaartfpDKKEREEIQTLKQQIADLREDLKRKETKwSSTHSRLRSQIQMLVRENTDLREE-----IKVMERFRLDAWKR 1055
Cdd:PTZ00121 1673 --------DKKKAEEAKKAEEDEKKAAEALKKEAEE-AKKAEELKKKEAEEKKKAEELKKAeeenkIKAEEAKKEAEEDK 1743

                         170
                  ....*....|....*...
gi 767977880 1056 AEAIESSLEVEKKDKLAN 1073
Cdd:PTZ00121 1744 KKAEEAKKDEEEKKKIAH 1761
PRK12704 PRK12704
phosphodiesterase; Provisional
 907-1059 2.02e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 2.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  907 REKIIELETEIEKFKAEnasLAKLRIERESALEKLRKEIADFEQQKAKELARIE----EFKKEEMRKLQKERKVFEKYTT 982
Cdd:PRK12704   56 KEALLEAKEEIHKLRNE---FEKELRERRNELQKLEKRLLQKEENLDRKLELLEkreeELEKKEKELEQKQQELEKKEEE 132

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767977880  983 AartfpDKKEREEIQTLkQQIADLREDLKRKETKwSSTHSRLRSQIQMLVREntdlreeikVMERFRLDAWKRAEAI 1059
Cdd:PRK12704  133 L-----EELIEEQLQEL-ERISGLTAEEAKEILL-EKVEEEARHEAAVLIKE---------IEEEAKEEADKKAKEI 193
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 906-1050 2.03e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.12  E-value: 2.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  906 LREKIIE-----LETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKAKELARIEEFKKEEMRKLQKERKVFEKY 980
Cdd:PRK00409  499 LPENIIEeakklIGEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQA 578

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767977880  981 TTAArtfpdKKEREE-IQTLKQQIADLREDLKRKETKwsSTHSRLRSQIQMLVRENTDLRE---EIKVMERFRL 1050
Cdd:PRK00409  579 IKEA-----KKEADEiIKELRQLQKGGYASVKAHELI--EARKRLNKANEKKEKKKKKQKEkqeELKVGDEVKY 645
alph_xenorhab_B NF033927
alpha-xenorhabdolysin family binary toxin subunit B;
912-1062 2.04e-03

alpha-xenorhabdolysin family binary toxin subunit B;


Pssm-ID: 411488 [Multi-domain]  Cd Length: 223  Bit Score: 41.08  E-value: 2.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  912 ELETEIEKFKAENASLAKLRIERESA--LEKLRKEIADFEQQKAKELARIEEFKkEEMRKLQKERKVFEKYTTAAR---T 986
Cdd:NF033927    8 ALRKSAAKIANKLDDLSQINLREATLdlLAQLQEQIAELEAQIAALESKLNELA-EDRKVIIEAIDLIEKYNIADLfkdL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  987 FPDKKE-------REEIQTLKQQIadlrEDLKRKETKWSS-------THSR--LRSQIQMLVRENTDLREEIKVMErFRL 1050
Cdd:NF033927   87 LPTAEEidslglpPPEKDLVKAAI----ERLKKLLGKISEgltyidlVEARdkLRDRINALLAESRTLDKDIKALA-GKL 161

                         170
                  ....*....|..
gi 767977880 1051 DAWKRAEAIESS 1062
Cdd:NF033927  162 EELTAIAAIDEE 173
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
907-1077 2.20e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.36  E-value: 2.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  907 REKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQ------QKAKELARIEEFKKEEMRKLQKERKVFEKY 980
Cdd:PRK03918  147 REKVVRQILGLDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENieelikEKEKELEEVLREINEISSELPELREELEKL 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  981 TTAARTFpdKKEREEIQTLKQQIADLREDLKRKETKWSSthsrLRSQIQMLVRENTDLREEIKVMERFRLDAWKRAEAIE 1060
Cdd:PRK03918  227 EKEVKEL--EELKEEIEELEKELESLEGSKRKLEEKIRE----LEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSE 300

                         170
                  ....*....|....*..
gi 767977880 1061 ssLEVEKKDKLANTSVR 1077
Cdd:PRK03918  301 --FYEEYLDELREIEKR 315
OmpH pfam03938
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...
 908-1005 2.36e-03

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.


Pssm-ID: 461098 [Multi-domain]  Cd Length: 140  Bit Score: 39.48  E-value: 2.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   908 EKIIEletEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKAKELARIEEFKKEEMRKLQKERKVFEKYTTAARTF 987
Cdd:pfam03938    8 QKILE---ESPEGKAAQAQLEKKFKKRQAELEAKQKELQKLYEELQKDGALLEEEREEKEQELQKKEQELQQLQQKAQQE 84

                           90
                   ....*....|....*...
gi 767977880   988 PDKKEREEIQTLKQQIAD 1005
Cdd:pfam03938   85 LQKKQQELLQPIQDKINK 102
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 901-1047 2.42e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.23  E-value: 2.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  901 ARSQVLREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKAKELARIEEFK--KEEMRKLQKERKVFE 978
Cdd:COG1196   665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEeqLEAEREELLEELLEE 744

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  979 KYTTAARTFPDKKEREEIQTLKQQIADLREDLKR------------KETKwsSTHSRLRSQIQMLVRENTDLREEIKVME 1046
Cdd:COG1196   745 EELLEEEALEELPEPPDLEELERELERLEREIEAlgpvnllaieeyEELE--ERYDFLSEQREDLEEARETLEEAIEEID 822


                  .
gi 767977880 1047 R 1047
Cdd:COG1196   823 R 823
HlpA COG2825
Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope ...
 901-973 2.69e-03

Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442073 [Multi-domain]  Cd Length: 171  Bit Score: 39.82  E-value: 2.69e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767977880  901 ARSQVLREKIIELETEIEKFKAENASL-AKLRIERESALEKLRKEIADFEQQKAKELARIEEfkkEEMRKLQKE 973
Cdd:COG2825    54 KRQAELQKLEKELQALQEKLQKEAATLsEEERQKKERELQKKQQELQRKQQEAQQDLQKRQQ---ELLQPILEK 124
OmpH pfam03938
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...
 900-973 2.96e-03

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.


Pssm-ID: 461098 [Multi-domain]  Cd Length: 140  Bit Score: 39.10  E-value: 2.96e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767977880   900 NARSQVLREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKAKELariEEFKKEEMRKLQKE 973
Cdd:pfam03938   29 KKRQAELEAKQKELQKLYEELQKDGALLEEEREEKEQELQKKEQELQQLQQKAQQEL---QKKQQELLQPIQDK 99
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
883-1025 3.23e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.54  E-value: 3.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  883 LGNELKLNISQDQPPGDNARSQVLREKIIELETEIekfkaenASLAKLRIERESALEKLRKEIADFEQQKAKELARIEEF 962
Cdd:COG3206   245 LRAQLGSGPDALPELLQSPVIQQLRAQLAELEAEL-------AELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILAS 317

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767977880  963 KKEEMRKLQKERKVFEKYTTAArtfpdKKEREEIQTLKQQIADLREDLKRKETKWSSTHSRLR 1025
Cdd:COG3206   318 LEAELEALQAREASLQAQLAQL-----EARLAELPELEAELRRLEREVEVARELYESLLQRLE 375
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 938-1072 3.82e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.29  E-value: 3.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  938 LEKLRKEIADFEQQKAKELARIEEFKKEemrkLQKERKVFEKYTTAArtfpdKKEREEIQTLKQQIADLREDLKRKETKw 1017
Cdd:COG1579    12 LQELDSELDRLEHRLKELPAELAELEDE----LAALEARLEAAKTEL-----EDLEKEIKRLELEIEEVEARIKKYEEQ- 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767977880 1018 SSTHSRLRsQIQMLVRENTDLREEIKVMERFRLDAWKRAEAIESSLEvEKKDKLA 1072
Cdd:COG1579    82 LGNVRNNK-EYEALQKEIESLKRRISDLEDEILELMERIEELEEELA-ELEAELA 134
MAT1 pfam06391
CDK-activating kinase assembly factor MAT1; MAT1 is an assembly/targeting factor for ...
 910-1041 5.77e-03

CDK-activating kinase assembly factor MAT1; MAT1 is an assembly/targeting factor for cyclin-dependent kinase-activating kinase (CAK), which interacts with the transcription factor TFIIH. The domain found to the N-terminal side of this domain is a C3HC4 RING finger.


Pssm-ID: 461894 [Multi-domain]  Cd Length: 202  Bit Score: 39.53  E-value: 5.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880   910 IIELETEIEKFKAENASLAKLRIERESA----LEKLRKEIADFEQQKAKELARIEEfkKEEMRKLQKERKVFEKYTTAAR 985
Cdd:pfam06391   63 VEETEKKIEQYEKENKDLILKNKMKLSQeeeeLEELLELEKREKEERRKEEKQEEE--EEKEKKEKAKQELIDELMTSNK 140

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 767977880   986 TFPDKKEREEiQTLKQQIADLREDLKRKETKWSSTHSRLRSQIQMLVRENTDLREE 1041
Cdd:pfam06391  141 DAEEIIAQHK-KTAKKRKSERRRKLEELNRVLEQKPTQFSTGIKFGQLPVPKIEEG 195
PTZ00121 PTZ00121
MAEBL; Provisional
 839-1070 6.84e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.89  E-value: 6.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  839 KRKIAPVKRGEDLSKSRRSRSpptsELMMKFFPSLKPKPKSDSHLGNELKLNISQ--------DQPPGDNARSQVLREKI 910
Cdd:PTZ00121 1574 EDKNMALRKAEEAKKAEEARI----EEVMKLYEEEKKMKAEEAKKAEEAKIKAEElkkaeeekKKVEQLKKKEAEEKKKA 1649

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  911 IELETEIEKFKAENASLAKLRIERESALEKLRKEIADfEQQKAKELARIEEFKK--EEMRKLQKERKvfekyttaaRTFP 988
Cdd:PTZ00121 1650 EELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEED-EKKAAEALKKEAEEAKkaEELKKKEAEEK---------KKAE 1719

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977880  989 DKKEREEIQTLKQQIADLREDLKRKETKWSSTHSRLRSQIQMLVRENTDLREEIKVMERFRLDAWKRAEAIESSLEVEKK 1068
Cdd:PTZ00121 1720 ELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKK 1799


                  ..
gi 767977880 1069 DK 1070
Cdd:PTZ00121 1800 IK 1801
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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