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Conserved domains on  [gi|767938560|ref|XP_011532926|]
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small integral membrane protein 23 isoform X2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4635 super family cl21283
Domain of unknown function (DUF4635); This family of proteins is found in eukaryotes. Proteins ...
 14-105 2.49e-48

Domain of unknown function (DUF4635); This family of proteins is found in eukaryotes. Proteins in this family are typically between 120 and 154 amino acids in length. There are two conserved sequence motifs: LEQ and DLE.


The actual alignment was detected with superfamily member pfam15466:

Pssm-ID: 406030  Cd Length: 134  Bit Score: 151.89  E-value: 2.49e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938560   14 STEIWGSSWEVSERIRECNYYQNLAVPQGLEYQTNEPSEEPIKTIRNWLKEKLHVFSEKLEEEVQQLEQLAWDLELWLDA 93
Cdd:pfam15466  43 GTGISGRSWEVSERIRECNYYQNPVASQGLEYQTKEPSEEPIKVLRNWLKENLHVFLEKLEEEVRELEQLVRDLELWLDA 122

                          90
                  ....*....|..
gi 767938560   94 LLGEPHQEEHCS 105
Cdd:pfam15466 123 LLGDPYLEEPCS 134
 
Name Accession Description Interval E-value
DUF4635 pfam15466
Domain of unknown function (DUF4635); This family of proteins is found in eukaryotes. Proteins ...
 14-105 2.49e-48

Domain of unknown function (DUF4635); This family of proteins is found in eukaryotes. Proteins in this family are typically between 120 and 154 amino acids in length. There are two conserved sequence motifs: LEQ and DLE.


Pssm-ID: 406030  Cd Length: 134  Bit Score: 151.89  E-value: 2.49e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938560   14 STEIWGSSWEVSERIRECNYYQNLAVPQGLEYQTNEPSEEPIKTIRNWLKEKLHVFSEKLEEEVQQLEQLAWDLELWLDA 93
Cdd:pfam15466  43 GTGISGRSWEVSERIRECNYYQNPVASQGLEYQTKEPSEEPIKVLRNWLKENLHVFLEKLEEEVRELEQLVRDLELWLDA 122

                          90
                  ....*....|..
gi 767938560   94 LLGEPHQEEHCS 105
Cdd:pfam15466 123 LLGDPYLEEPCS 134
 
Name Accession Description Interval E-value
DUF4635 pfam15466
Domain of unknown function (DUF4635); This family of proteins is found in eukaryotes. Proteins ...
 14-105 2.49e-48

Domain of unknown function (DUF4635); This family of proteins is found in eukaryotes. Proteins in this family are typically between 120 and 154 amino acids in length. There are two conserved sequence motifs: LEQ and DLE.


Pssm-ID: 406030  Cd Length: 134  Bit Score: 151.89  E-value: 2.49e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767938560   14 STEIWGSSWEVSERIRECNYYQNLAVPQGLEYQTNEPSEEPIKTIRNWLKEKLHVFSEKLEEEVQQLEQLAWDLELWLDA 93
Cdd:pfam15466  43 GTGISGRSWEVSERIRECNYYQNPVASQGLEYQTKEPSEEPIKVLRNWLKENLHVFLEKLEEEVRELEQLVRDLELWLDA 122

                          90
                  ....*....|..
gi 767938560   94 LLGEPHQEEHCS 105
Cdd:pfam15466 123 LLGDPYLEEPCS 134
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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