|
Name |
Accession |
Description |
Interval |
E-value |
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1-1165 |
1.19e-89 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 314.60 E-value: 1.19e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 1 MDALSFVMGEKIA-NLRVKNIQELIHgaHIGKPISSSASVKIIYVEESGEEKT-------FARIIRGGCSEFRFNDNLVS 72
Cdd:pfam02463 40 LDAILFVLGERSAkSLRSERLSDLIH--SKSGAFVNSAEVEITFDNEDHELPIdkeevsiRRRVYRGGDSEYYINGKNVT 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 73 RSVYIAELEKIGIIVKAQNCLVFQGTVESISVKKPKERTQFFEEISTSGELIGEYEEKKRKLQKAEEDAQFNFNKKKNIA 152
Cdd:pfam02463 118 KKEVAELLESQGISPEAYNFLVQGGKIEIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 153 AERRQAKLEKEEAERYQSLLEELKMNKIQLQLFQLYHNEKKIHLLNTKLEHVNRDLSVKRESLSHHENIVKARKKEHGML 232
Cdd:pfam02463 198 QELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEE 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 233 TRQLQQTEKELKSVETLLNQKRPQYIKAKENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQ 312
Cdd:pfam02463 278 EKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEE 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 313 IEEEILHKKRDIELEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQGNLKQIKEQIEDHKK 392
Cdd:pfam02463 358 EEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEE 437
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 393 RIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEELNLIRSELQNAGIDTHEGKRQQKRAEVLEHLKRLYPD 472
Cdd:pfam02463 438 SIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIK 517
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 473 SVFGRLFDLCHPIHKKYQLAVTKVFGRFITAIVVASEKVAKDCIRFLKEERAEPETFLALDYLDIKPINERLRELKGCKM 552
Cdd:pfam02463 518 DGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVL 597
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 553 VIDVIKTQFPQLKKVIQFVCGNGLVCETMEEARHIALSGpERQKTVALDGTLFLKSGVISGGSSDLKYKARcwdekelkn 632
Cdd:pfam02463 598 EIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTK-LKESAKAKESGLRKGVSLEEGLAEKSEVKAS--------- 667
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 633 lrdrrsqkiqelkglMKTLRKETDLKQIQTLIQGTQTRLKYSQNELEMIKKKhlvafyqEQSQLQSELLNIESQCIMLSE 712
Cdd:pfam02463 668 ---------------LSELTKELLEIQELQEKAESELAKEEILRRQLEIKKK-------EQREKEELKKLKLEAEELLAD 725
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 713 GIKERQRRIKEFQEKIDKVEDDIFQhfCEEIGVENIREFENKHVKRQQEIDQKRLEFEKQKTRLNVQLEYsrshlKKKLN 792
Cdd:pfam02463 726 RVQEAQDKINEELKLLKQKIDEEEE--EEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKE-----EKLKA 798
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 793 KINTLKETIQKGSEDIDHLKKAEENCLQTVNELMAKQQQLKdirvtQNSSAEKVQTQIEEERKKFLAVDREVGKLQKEVV 872
Cdd:pfam02463 799 QEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELA-----LELKEEQKLEKLAEEELERLEEEITKEELLQELL 873
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 873 SIQTSLEQKRLEKHNLLLDCKVQDIEIILLSGSLDDIIEVEMGTEAESTQATIDIYekeeafEIDYSSLKEDLKALQSDQ 952
Cdd:pfam02463 874 LKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEI------LLKYEEEPEELLLEEADE 947
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 953 EIEAHLRLLLQQVASQEDILLKTAAPNLRALENLKTVRDKFQESTDAFEASRKEARLCRQEFEQVKKRRYDLFTQCFEHV 1032
Cdd:pfam02463 948 KEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFV 1027
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 1033 SISIDQIYKKLCRNNSAQAFLSPENPEEPYLEGISYNCVAPGKRFMPMDNLSGGEKCVAALALLFAVHSFRPAPFFVLDE 1112
Cdd:pfam02463 1028 SINKGWNKVFFYLELGGSAELRLEDPDDPFSGGIEISARPPGKGVKNLDLLSGGEKTLVALALIFAIQKYKPAPFYLLDE 1107
|
1130 1140 1150 1160 1170
....*....|....*....|....*....|....*....|....*....|...
gi 768024649 1113 VDAALDNTNIGKVSSYIKEQTqDQFQMIVISLKEEFYSRADALIGIYPEYDDC 1165
Cdd:pfam02463 1108 IDAALDDQNVSRVANLLKELS-KNAQFIVISLREEMLEKADKLVGVTMVENGV 1159
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2-1158 |
1.03e-73 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 267.70 E-value: 1.03e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 2 DALSFVMGEK-IANLRVKNIQELIHGAHIGKPiSSSASVKIIYVEESGEEKTFARIIR-------GGCSEFRFNDNLVSR 73
Cdd:TIGR02169 41 DAILFALGLSsSKAMRAERLSDLISNGKNGQS-GNEAYVTVTFKNDDGKFPDELEVVRrlkvtddGKYSYYYLNGQRVRL 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 74 SVYIAELEKIGIIVKAQNcLVFQGTVESISVKKPKERTQFFEEISTsgelIGEYEEKKRKLQKAEEDAQFNFNKKKNIAA 153
Cdd:TIGR02169 120 SEIHDFLAAAGIYPEGYN-VVLQGDVTDFISMSPVERRKIIDEIAG----VAEFDRKKEKALEELEEVEENIERLDLIID 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 154 ERRQA----KLEKEEAERYQSLLEELkmnkiqlQLFQLYHNEKKIHLLNTKLEHVNRDLSVKRESLSHhenivkarkkeh 229
Cdd:TIGR02169 195 EKRQQlerlRREREKAERYQALLKEK-------REYEGYELLKEKEALERQKEAIERQLASLEEELEK------------ 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 230 gmLTRQLQQTEKELKSVETLLNQKRPQYIKAKENTSHHLKKldvakkSIKDSEKQCSKQEDDIKALETELADLDAAwrsf 309
Cdd:TIGR02169 256 --LTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKE------KIGELEAEIASLERSIAEKERELEDAEER---- 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 310 EKQIEEEILHKKRDIELEASQLDRYKELKEQVRKKVATMTQQLEKLQ------------WEQKTDEERLAFE--KRRHGE 375
Cdd:TIGR02169 324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRaeleevdkefaeTRDELKDYREKLEklKREINE 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 376 VQGNLK--------------QIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEELNLIRS 441
Cdd:TIGR02169 404 LKRELDrlqeelqrlseelaDLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEK 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 442 ELQNAG--IDTHEGKRQQKRAEVL-----EHLKRLYPDSVFGRLFDLCHpIHKKYQLAVTKVFGRFITAIVVASEKVAKD 514
Cdd:TIGR02169 484 ELSKLQreLAEAEAQARASEERVRggravEEVLKASIQGVHGTVAQLGS-VGERYATAIEVAAGNRLNNVVVEDDAVAKE 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 515 CIRFLKEERAEPETFLALDYLDIKPINERLRELKGC-KMVIDVIKTQfPQLKKVIQFVCGNGLVCETMEEARhiALSGPE 593
Cdd:TIGR02169 563 AIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGViGFAVDLVEFD-PKYEPAFKYVFGDTLVVEDIEAAR--RLMGKY 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 594 RqkTVALDGTLFLKSGVISGGSsdLKYKARCWDEKELKNLRDRRSQKIQELKGLMKTLRKETD-----LKQIQTLIQGTQ 668
Cdd:TIGR02169 640 R--MVTLEGELFEKSGAMTGGS--RAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRrienrLDELSQELSDAS 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 669 TRLKYSQNELEMIKKKH------LVAFYQEQSQLQSELLNIESQCIMLSEGIKERQRRIKEFQEKIDKVEDDIFQHFCEE 742
Cdd:TIGR02169 716 RKIGEIEKEIEQLEQEEeklkerLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPE 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 743 IGVEnIREFENKHvkrqQEIDQKRLEFEKQKTRLNVQLEYSRSHLKKKLNKINTLKETIQKGSEDIDHLKKAEENCLQTV 822
Cdd:TIGR02169 796 IQAE-LSKLEEEV----SRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEEL 870
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 823 NELMAKQQQLkdirvtqnssaEKVQTQIEEERKKflaVDREVGKLQKEVVSIQTSLEQKRLekhnLLLDCKVQdieiill 902
Cdd:TIGR02169 871 EELEAALRDL-----------ESRLGDLKKERDE---LEAQLRELERKIEELEAQIEKKRK----RLSELKAK------- 925
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 903 sgslddiievemgteAESTQATIDIYEKEEAFEIDYSSLKEDLKALQSD-QEIEAHLRLLlqqvasqEDIllktaapNLR 981
Cdd:TIGR02169 926 ---------------LEALEEELSEIEDPKGEDEEIPEEELSLEDVQAElQRVEEEIRAL-------EPV-------NML 976
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 982 ALENLKTV---RDKFQESTDAFEASRKEARLCRQEFEQVKKrryDLFTQCFEHVSISIDQIYKKLcrnNSAQAFLSPENP 1058
Cdd:TIGR02169 977 AIQEYEEVlkrLDELKEKRAKLEEERKAILERIEEYEKKKR---EVFMEAFEAINENFNEIFAEL---SGGTGELILENP 1050
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 1059 EEPYLEGISYNCVAPGKRFMPMDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSSYIKEQTQDQfQ 1138
Cdd:TIGR02169 1051 DDPFAGGLELSAKPKGKPVQRLEAMSGGEKSLTALSFIFAIQRYKPSPFYAFDEVDMFLDGVNVERVAKLIREKAGEA-Q 1129
|
1210 1220
....*....|....*....|
gi 768024649 1139 MIVISLKEEFYSRADALIGI 1158
Cdd:TIGR02169 1130 FIVVSLRSPMIEYADRAIGV 1149
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2-1158 |
4.89e-67 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 247.28 E-value: 4.89e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 2 DALSFVMGE-KIANLRVKNIQELIHGAHIGKPISSSASVKIIYVEESGEEKTFA--------RIIRGGCSEFRFNDNLVs 72
Cdd:TIGR02168 41 DAIRWVLGEqSAKALRGGKMEDVIFNGSETRKPLSLAEVELVFDNSDGLLPGADyseisitrRLYRDGESEYFINGQPC- 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 73 RSVYIAEL--------EKIGIIVkaqnclvfQGTVESISVKKPKERTQFFEEisTSGelIGEYEEKKRKLQKAEEDAQFN 144
Cdd:TIGR02168 120 RLKDIQDLfldtglgkRSYSIIE--------QGKISEIIEAKPEERRAIFEE--AAG--ISKYKERRKETERKLERTREN 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 145 FNKKKNIAAE--RRQAKLEK--EEAERYQSLLEELKMNKIQLQLFQLYHNEKKIHLLNTKLEHVNRDLSVKRESLSHHEN 220
Cdd:TIGR02168 188 LDRLEDILNEleRQLKSLERqaEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 221 IVKARKKEHGMLTRQLQQTEKELKSVETLLNQKRPQYIKAKENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELA 300
Cdd:TIGR02168 268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE 347
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 301 DLDAAWRSFEKQIEEeilhKKRDIELEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHG----EV 376
Cdd:TIGR02168 348 ELKEELESLEAELEE----LEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRErlqqEI 423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 377 QGNLKQIKE-QIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEELNLIRSELQN-AGIDTHEGK 454
Cdd:TIGR02168 424 EELLKKLEEaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSlERLQENLEG 503
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 455 RQQKRAEVLEHLKRLypDSVFGRLFDLCHpIHKKYQLAVTKVFGRFITAIVVASEKVAKDCIRFLKEERAEPETFLALDY 534
Cdd:TIGR02168 504 FSEGVKALLKNQSGL--SGILGVLSELIS-VDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDS 580
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 535 LDIKPIN----ERLRELKGCKMVIDVIKTQFPQLKKVIQFVCGNGLVCETMEEARHIALSGPERQKTVALDGTLFLKSGV 610
Cdd:TIGR02168 581 IKGTEIQgndrEILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGV 660
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 611 ISGGSSdlkykarcwdekELKNLRDRRSQKIQELKGLMKTLrkETDLKQIQTLIQGTQTRLKYSQNELEMIKKKhLVAFY 690
Cdd:TIGR02168 661 ITGGSA------------KTNSSILERRREIEELEEKIEEL--EEKIAELEKALAELRKELEELEEELEQLRKE-LEELS 725
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 691 QEQSQLQSELLNIESQCIMLSEGIKERQRRIKEFQEKIDKVEDDIFQHFceeigvENIREFENKHVKRQQEIDQKRLEFE 770
Cdd:TIGR02168 726 RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE------EELAEAEAEIEELEAQIEQLKEELK 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 771 KQKTRLnvqleysrshlKKKLNKINTLKETIQKGSEDIDHLKKAEENCLQTVNELMAKQQQLKDIRVTQNSSAEKVQTQI 850
Cdd:TIGR02168 800 ALREAL-----------DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELI 868
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 851 EEERKKFLAVDREVGKLQKEVVSIQTSLEQKRLEKHNLLLDCKVQDIEIILLSGSLDDIIEVEMGTEAEstqatidIYEK 930
Cdd:TIGR02168 869 EELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVR-------IDNL 941
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 931 EEAFEIDYSSLKEDLKALQSD-----QEIEAHLRLLLQQVASQEDIllktaapNLRALENLKTVRDKFQESTDAFEASRK 1005
Cdd:TIGR02168 942 QERLSEEYSLTLEEAEALENKieddeEEARRRLKRLENKIKELGPV-------NLAAIEEYEELKERYDFLTAQKEDLTE 1014
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 1006 EARLCRQEFEQVKKRRYDLFTQCFEHVSISIDQIYKKLCRNNSAQ-AFLSPENPEEpylEGISYNCVAPGKRFMPMDNLS 1084
Cdd:TIGR02168 1015 AKETLEEAIEEIDREARERFKDTFDQVNENFQRVFPKLFGGGEAElRLTDPEDLLE---AGIEIFAQPPGKKNQNLSLLS 1091
|
1130 1140 1150 1160 1170 1180 1190
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 768024649 1085 GGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSSYIKEQTqDQFQMIVISLKEEFYSRADALIGI 1158
Cdd:TIGR02168 1092 GGEKALTALALLFAIFKVKPAPFCILDEVDAPLDDANVERFANLLKEFS-KNTQFIVITHNKGTMEVADQLYGV 1164
|
|
| ABC_SMC1_euk |
cd03275 |
ATP-binding cassette domain of eukaryotic SMC1 proteins; The structural maintenance of ... |
1072-1175 |
5.71e-65 |
|
ATP-binding cassette domain of eukaryotic SMC1 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213242 [Multi-domain] Cd Length: 247 Bit Score: 220.14 E-value: 5.71e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 1072 APGKRFMPMDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSSYIKEQTQDQFQMIVISLKEEFYSR 1151
Cdd:cd03275 145 PPGKRFRDMDNLSGGEKTMAALALLFAIHSYQPAPFFVLDEVDAALDNTNVGKVASYIREQAGPNFQFIVISLKEEFFSK 224
|
90 100
....*....|....*....|....
gi 768024649 1152 ADALIGIYPEYdDCMFSRVLTLDL 1175
Cdd:cd03275 225 ADALVGVYRDQ-ECNSSKVLTLDL 247
|
|
| ABC_SMC1_euk |
cd03275 |
ATP-binding cassette domain of eukaryotic SMC1 proteins; The structural maintenance of ... |
1-107 |
3.62e-50 |
|
ATP-binding cassette domain of eukaryotic SMC1 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213242 [Multi-domain] Cd Length: 247 Bit Score: 177.76 E-value: 3.62e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 1 MDALSFVMGEKIANLRVKNIQELIHGAHIGKPISSSASVKIIYVEESGEEKTFARIIRGGCSEFRFNDNLVSRSVYIAEL 80
Cdd:cd03275 39 MDAISFVLGEKSSHLRSKNLKDLIYRARVGKPDSNSAYVTAVYEDDDGEEKTFRRIITGGSSSYRINGKVVSLKEYNEEL 118
|
90 100
....*....|....*....|....*..
gi 768024649 81 EKIGIIVKAQNCLVFQGTVESISVKKP 107
Cdd:cd03275 119 EKINILVKARNFLVFQGDVESIASKNP 145
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1-730 |
1.51e-33 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 140.46 E-value: 1.51e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 1 MDALSFVMGE-KIANLRVKNIQELIH-GAHIGKPiSSSASVKIIYVEESG------EEKTFARII-RGGCSEFRFNDNLV 71
Cdd:COG1196 41 VDAIRWVLGEqSAKSLRGGKMEDVIFaGSSSRKP-LGRAEVSLTFDNSDGtlpidyDEVTITRRLyRSGESEYYINGKPC 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 72 SRSVyIAEL-EKIGIIVKAQNcLVFQGTVESISVKKPKERTQFFEEIStsGelIGEYEEKK----RKLQKAEEdaqfNFN 146
Cdd:COG1196 120 RLKD-IQDLfLDTGLGPESYS-IIGQGMIDRIIEAKPEERRAIIEEAA--G--ISKYKERKeeaeRKLEATEE----NLE 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 147 KKKNIAAE--RRQAKLEK--EEAERYQSLLEELKMNKIQLQLFQLYHNEKKIHLLNTKLEHVNRDLSVKRESLSHHENIV 222
Cdd:COG1196 190 RLEDILGEleRQLEPLERqaEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAEL 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 223 KARKKEHGMLTRQLQQTEKELKSVETLLNQKRPQYIKAKENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADL 302
Cdd:COG1196 270 EELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEA 349
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 303 DAAWRSFEKQIEEEILHKKRDIELEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQGNLKQ 382
Cdd:COG1196 350 EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEA 429
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 383 IKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEELNLI-----RSELQNAGIDTHEGKRQQ 457
Cdd:COG1196 430 LAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELaeaaaRLLLLLEAEADYEGFLEG 509
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 458 KRAEVLEHLKRLYPDSVFGRLFDLchpihKKYQLAVTKVFGRFITAIVVASEKVAKDCIRFLKEERAEPETFLALD---- 533
Cdd:COG1196 510 VKAALLLAGLRGLAGAVAVLIGVE-----AAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDkira 584
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 534 YLDIKPINERLRELKGCKMVIDVIKTQFPQLKKVIQFVCGNGLVCETMEEARHIALSGPERQKTVALDGTLFLKSGVISG 613
Cdd:COG1196 585 RAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTG 664
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 614 GSSDLKYKARcwdEKELKNLRDRRSQKIQELKGLMKTLRKETDLKQIQTLIQGTQTRLKYSQNELEMIKKKHLVAFYQEQ 693
Cdd:COG1196 665 GSRRELLAAL---LEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEEL 741
|
730 740 750
....*....|....*....|....*....|....*..
gi 768024649 694 SQLQSELLNIESQCIMLSEGIKERQRRIKEFQEKIDK 730
Cdd:COG1196 742 LEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
|
|
| ABC_SMC_barmotin |
cd03278 |
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a ... |
1072-1158 |
2.20e-28 |
|
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a tight junction-associated protein expressed in rat epithelial cells which is thought to have an important regulatory role in tight junction barrier function. Barmotin belongs to the SMC protein family. SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213245 [Multi-domain] Cd Length: 197 Bit Score: 113.33 E-value: 2.20e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 1072 APGKRFMPMDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSSYIKEQTqDQFQMIVISLKEEFYSR 1151
Cdd:cd03278 103 APGKKVQRLSLLSGGEKALTALALLFAIFRVRPSPFCVLDEVDAALDDANVERFARLLKEFS-KETQFIVITHRKGTMEA 181
|
....*..
gi 768024649 1152 ADALIGI 1158
Cdd:cd03278 182 ADRLYGV 188
|
|
| SMC_hinge |
smart00968 |
SMC proteins Flexible Hinge Domain; This entry represents the hinge region of the SMC ... |
472-587 |
9.15e-27 |
|
SMC proteins Flexible Hinge Domain; This entry represents the hinge region of the SMC (Structural Maintenance of Chromosomes) family of proteins. The hinge region is responsible for formation of the DNA interacting dimer. It is also possible that the precise structure of it is an essential determinant of the specificity of the DNA-protein interaction.
Pssm-ID: 214944 [Multi-domain] Cd Length: 120 Bit Score: 106.16 E-value: 9.15e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 472 DSVFGRLFDLCHpIHKKYQLAVTKVFGRFITAIVVASEKVAKDCIRFLKEERAEPETFLALDYLDIKPI-NERLRELK-- 548
Cdd:smart00968 1 PGVLGRVADLIS-VDPKYETALEAALGGRLQAVVVDTEETAKKAIEFLKKNRLGRATFLPLDKIKPRSPaGSKLREALlp 79
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 768024649 549 ---GCKMVIDVIKTQfPQLKKVIQFVCGNGLVCETMEEARHI 587
Cdd:smart00968 80 epgFVGPAIDLVEYD-PELRPALEYLLGNTLVVDDLETARRL 120
|
|
| ABC_SMC4_euk |
cd03274 |
ATP-binding cassette domain of eukaryotic SMC4 proteins; The structural maintenance of ... |
1073-1163 |
9.88e-26 |
|
ATP-binding cassette domain of eukaryotic SMC4 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213241 [Multi-domain] Cd Length: 212 Bit Score: 106.23 E-value: 9.88e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 1073 PGKRFMPMDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSSYIKEQTQDQfQMIVISLKEEFYSRA 1152
Cdd:cd03274 118 PKKSWKNISNLSGGEKTLSSLALVFALHHYKPTPLYVMDEIDAALDFRNVSIVANYIKERTKNA-QFIVISLRNNMFELA 196
|
90
....*....|.
gi 768024649 1153 DALIGIYPEYD 1163
Cdd:cd03274 197 DRLVGIYKTNN 207
|
|
| ABC_SMC_head |
cd03239 |
The SMC head domain belongs to the ATP-binding cassette superfamily; The structural ... |
1083-1159 |
1.43e-23 |
|
The SMC head domain belongs to the ATP-binding cassette superfamily; The structural maintenance of chromosomes (SMC) proteins are essential for successful chromosome transmission during replication and segregation of the genome in all organisms. SMCs are generally present as single proteins in bacteria, and as at least six distinct proteins in eukaryotes. The proteins range in size from approximately 110 to 170 kDa, and each has five distinct domains: amino- and carboxy-terminal globular domains, which contain sequences characteristic of ATPases, two coiled-coil regions separating the terminal domains , and a central flexible hinge. SMC proteins function together with other proteins in a range of chromosomal transactions, including chromosome condensation, sister-chromatid cohesion, recombination, DNA repair, and epigenetic silencing of gene expression.
Pssm-ID: 213206 [Multi-domain] Cd Length: 178 Bit Score: 98.92 E-value: 1.43e-23
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 768024649 1083 LSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSSYIKEQTQDQFQMIVISLKEEFYSRADALIGIY 1159
Cdd:cd03239 95 LSGGEKSLSALALIFALQEIKPSPFYVLDEIDAALDPTNRRRVSDMIKEMAKHTSQFIVITLKKEMFENADKLIGVL 171
|
|
| SMC_hinge |
pfam06470 |
SMC proteins Flexible Hinge Domain; This family represents the hinge region of the SMC ... |
472-588 |
1.54e-20 |
|
SMC proteins Flexible Hinge Domain; This family represents the hinge region of the SMC (Structural Maintenance of Chromosomes) family of proteins. The hinge region is responsible for formation of the DNA interacting dimer. It is also possible that the precise structure of it is an essential determinant of the specificity of the DNA-protein interaction.
Pssm-ID: 461926 [Multi-domain] Cd Length: 116 Bit Score: 88.09 E-value: 1.54e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 472 DSVFGRLFDLCHpIHKKYQLAVTKVFGRFITAIVVASEKVAKDCIRFLKEERAEPETFLALDYLDIKPINERLRELKGCK 551
Cdd:pfam06470 2 KGVLGRLADLIE-VDEGYEKAVEAALGGRLQAVVVDDEDDAKRAIEFLKKNKLGRATFLPLDRLKPRPRRPGADLKGGAG 80
|
90 100 110
....*....|....*....|....*....|....*..
gi 768024649 552 MVIDVIKTQfPQLKKVIQFVCGNGLVCETMEEARHIA 588
Cdd:pfam06470 81 PLLDLVEYD-DEYRKALRYLLGNTLVVDDLDEALELA 116
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
1083-1161 |
4.52e-20 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 88.57 E-value: 4.52e-20
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768024649 1083 LSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSSYIKEQTQDQFQMIVISLKEEFYSRADALIGIYPE 1161
Cdd:cd03227 78 LSGGEKELSALALILALASLKPRPLYILDEIDRGLDPRDGQALAEAILEHLVKGAQVIVITHLPELAELADKLIHIKKV 156
|
|
| ABC_SMC2_euk |
cd03273 |
ATP-binding cassette domain of eukaryotic SMC2 proteins; The structural maintenance of ... |
1083-1155 |
6.94e-15 |
|
ATP-binding cassette domain of eukaryotic SMC2 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213240 [Multi-domain] Cd Length: 251 Bit Score: 75.80 E-value: 6.94e-15
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 768024649 1083 LSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALD--NT-NIGKVssyIKEQ-TQDQFqmIVISLKEEFYSRADAL 1155
Cdd:cd03273 167 LSGGQRSLVALSLILALLLFKPAPMYILDEVDAALDlsHTqNIGRM---IKTHfKGSQF--IVVSLKEGMFNNANVL 238
|
|
| ABC_SMC3_euk |
cd03272 |
ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of ... |
1080-1158 |
3.86e-12 |
|
ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213239 [Multi-domain] Cd Length: 243 Bit Score: 67.67 E-value: 3.86e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768024649 1080 MDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSSYIKEQTqDQFQMIVISLKEEFYSRADALIGI 1158
Cdd:cd03272 156 MQQLSGGQKSLVALALIFAIQKCDPAPFYLFDEIDAALDAQYRTAVANMIKELS-DGAQFITTTFRPELLEVADKFYGV 233
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
104-468 |
4.78e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 64.39 E-value: 4.78e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 104 VKKPKERTQFFEEISTSGELIGEYEEKKRKL----QKAEEDAQFNFNKKKniAAERRQA---KLEKEEAERYQSLLEELK 176
Cdd:PTZ00121 1390 KKKADEAKKKAEEDKKKADELKKAAAAKKKAdeakKKAEEKKKADEAKKK--AEEAKKAdeaKKKAEEAKKAEEAKKKAE 1467
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 177 MNKIQLQLFQLYHNEKKIHLLNTKLEHVNRDLSVKRESLSHHENIVKARKKEHGMLTRQLQQTEK-----ELKSVETLln 251
Cdd:PTZ00121 1468 EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEakkadEAKKAEEK-- 1545
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 252 QKRPQYIKAKE-NTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSfEKQIEEEILHKKRDIELEASQ 330
Cdd:PTZ00121 1546 KKADELKKAEElKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEE-EKKMKAEEAKKAEEAKIKAEE 1624
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 331 LDRYKELK---EQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCMDC 407
Cdd:PTZ00121 1625 LKKAEEEKkkvEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKA 1704
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 768024649 408 LKEKKQQEEtlvdeiEKTKSRMSEVNEELNLIRSElqNAGIDTHEGKRQQKRAEVLEHLKR 468
Cdd:PTZ00121 1705 EELKKKEAE------EKKKAEELKKAEEENKIKAE--EAKKEAEEDKKKAEEAKKDEEEKK 1757
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
203-816 |
1.25e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 59.31 E-value: 1.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 203 HVNRDLSVKRESLSHHENIvKARKKEHGmltRQLQQTEKELKSvetlLNQKRPQYIKAKENTSHHLKKLDVAKKSIKDSE 282
Cdd:PRK03918 173 EIKRRIERLEKFIKRTENI-EELIKEKE---KELEEVLREINE----ISSELPELREELEKLEKEVKELEELKEEIEELE 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 283 KQCSKQEDDIKALETELADLDAAWRSFEKQIE--EEILHKKRDIELEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQK 360
Cdd:PRK03918 245 KELESLEGSKRKLEEKIRELEERIEELKKEIEelEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEIN 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 361 TDEERLA---FEKRRHGEVQGNLKQIKEQIEDHKKRIEKLEEY--TKTCMDCLKEKKQQE--ETLVDEIEKTKSRMSEVN 433
Cdd:PRK03918 325 GIEERIKeleEKEERLEELKKKLKELEKRLEELEERHELYEEAkaKKEELERLKKRLTGLtpEKLEKELEELEKAKEEIE 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 434 EELNLIRSELqnAGIDThEGKRQQKRAEVLEHLKRLYPdsVFGRLFDLCH--PIHKKYQLAVTKVFGRFITaivvasekv 511
Cdd:PRK03918 405 EEISKITARI--GELKK-EIKELKKAIEELKKAKGKCP--VCGRELTEEHrkELLEEYTAELKRIEKELKE--------- 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 512 AKDCIRFLKEERAEPETFLaldyldikpinERLRELKGCKMVIDVIKTQFPQLKKViqfvcgnglVCETMEEARHialsg 591
Cdd:PRK03918 471 IEEKERKLRKELRELEKVL-----------KKESELIKLKELAEQLKELEEKLKKY---------NLEELEKKAE----- 525
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 592 pERQKTVALDGTLflkSGVISGGSSDLKykarcwDEKELKNLRDRRSQKIQELKGLMKTLrketdLKQIQTLIQGTQTRL 671
Cdd:PRK03918 526 -EYEKLKEKLIKL---KGEIKSLKKELE------KLEELKKKLAELEKKLDELEEELAEL-----LKELEELGFESVEEL 590
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 672 KYSQNELEMIKKKHLVAFYQEqSQLQSELLNIESQCIMLSEGIKERQRRIKEFQEKIDKVEDdifqhFCEEIGVENIREF 751
Cdd:PRK03918 591 EERLKELEPFYNEYLELKDAE-KELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE-----LEKKYSEEEYEEL 664
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768024649 752 ENKHVKRQQEIDQKRLEFEkqktrlnvQLEYSRSHLKKKLNKINTLKETIQKGSEDIDHLKKAEE 816
Cdd:PRK03918 665 REEYLELSRELAGLRAELE--------ELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALE 721
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
104-435 |
2.26e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 59.00 E-value: 2.26e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 104 VKKPKERTQFFEEISTSGELIGEYEEKKRK---LQKAEEDAQFNFNKKKniAAERRQAKLEKEEAERYQSLLEELKMNKi 180
Cdd:PTZ00121 1430 KKKADEAKKKAEEAKKADEAKKKAEEAKKAeeaKKKAEEAKKADEAKKK--AEEAKKADEAKKKAEEAKKKADEAKKAA- 1506
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 181 qlqlfqlyHNEKKIHLLNTKLEHVNRDLSVKRESLSHHENIVKARKKEHGMLTRQLQQTEK--ELKSVEtllnQKRpqyi 258
Cdd:PTZ00121 1507 --------EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKaeEKKKAE----EAK---- 1570
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 259 KAKENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEEILHKKRDIEL---------EAS 329
Cdd:PTZ00121 1571 KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLkkkeaeekkKAE 1650
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 330 QLDRYKEL----KEQVRKKVATMTQQLEKLQWEQKtDEERLAFEKRRHGEVQGNLKQIKEQIEDHKKRIEKL---EEYTK 402
Cdd:PTZ00121 1651 ELKKAEEEnkikAAEEAKKAEEDKKKAEEAKKAEE-DEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELkkaEEENK 1729
|
330 340 350
....*....|....*....|....*....|....*...
gi 768024649 403 TCMDCLK-----EKKQQEETLVDEIEKTKSRMSEVNEE 435
Cdd:PTZ00121 1730 IKAEEAKkeaeeDKKKAEEAKKDEEEKKKIAHLKKEEE 1767
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
235-435 |
2.59e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.47 E-value: 2.59e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 235 QLQQTEKELKSVETLLNQKRPQYIKAKENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIE 314
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 315 E---------------------EILHKKRDIELEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRH 373
Cdd:COG4942 101 AqkeelaellralyrlgrqpplALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 768024649 374 GEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEE 435
Cdd:COG4942 181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
289-470 |
3.99e-08 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 55.32 E-value: 3.99e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 289 EDDIKALEtELADLDAAWRSFEKQIEE---EILHKKRDIELEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEER 365
Cdd:COG1579 3 PEDLRALL-DLQELDSELDRLEHRLKElpaELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 366 LafekrrhGEVQGN--LKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEELNLIRSEL 443
Cdd:COG1579 82 L-------GNVRNNkeYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAEL 154
|
170 180
....*....|....*....|....*..
gi 768024649 444 QNAgIDTHEGKRQQKRAEVLEHLKRLY 470
Cdd:COG1579 155 EAE-LEELEAEREELAAKIPPELLALY 180
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
128-428 |
5.34e-08 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 57.65 E-value: 5.34e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 128 EEKKRKLQKAEEDAQFNFNKKKNIAAER-RQAKL--EKEEAERYQSLLE-ELKMNKIQLQLFQ--LYHNEKkihllntkL 201
Cdd:COG3096 278 NERRELSERALELRRELFGARRQLAEEQyRLVEMarELEELSARESDLEqDYQAASDHLNLVQtaLRQQEK--------I 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 202 EHVNRDLSVKRESLSHHENIVKARKKEHGMLTRQLQQTEKELKSVETLL---------NQKRP-QY---IKAKENTSHHL 268
Cdd:COG3096 350 ERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLadyqqaldvQQTRAiQYqqaVQALEKARALC 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 269 KKLDVAKKSIKDSEKQCSKQEDDIK----ALETELADLDAAWRSFEKQIEeeiLHKKRDIELEASQ--------LDRYKE 336
Cdd:COG3096 430 GLPDLTPENAEDYLAAFRAKEQQATeevlELEQKLSVADAARRQFEKAYE---LVCKIAGEVERSQawqtarelLRRYRS 506
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 337 LKEQVrKKVATMTQQLEKL--QWEQKTDEERLA--FEKRRHGEVQGNLkQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKK 412
Cdd:COG3096 507 QQALA-QRLQQLRAQLAELeqRLRQQQNAERLLeeFCQRIGQQLDAAE-ELEELLAELEAQLEELEEQAAEAVEQRSELR 584
|
330
....*....|....*.
gi 768024649 413 QQEETLVDEIEKTKSR 428
Cdd:COG3096 585 QQLEQLRARIKELAAR 600
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
257-888 |
2.30e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 55.46 E-value: 2.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 257 YIKAKENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLdaawrsfEKQIEEeILHKKRDIELEASQLDRYKE 336
Cdd:PRK03918 160 YENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEV-------LREINE-ISSELPELREELEKLEKEVK 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 337 LKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQGNLKQIKEQIEDHKKRIEKLEEYTKtcmdcLKEKKQQEE 416
Cdd:PRK03918 232 ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIK-----LSEFYEEYL 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 417 TLVDEIEKTKSRMSevnEELNLIRSELQNAGIDTHE-GKRQQKRAEVLEHLKRLYPDSvfgRLFDLCHPIHKKYQLAVTK 495
Cdd:PRK03918 307 DELREIEKRLSRLE---EEINGIEERIKELEEKEERlEELKKKLKELEKRLEELEERH---ELYEEAKAKKEELERLKKR 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 496 VFGRFItaivvasEKVAKDcIRFLKEERAEPEtflaldyLDIKPINERLRELKGckmVIDVIKTQFPQLK--KVIQFVCG 573
Cdd:PRK03918 381 LTGLTP-------EKLEKE-LEELEKAKEEIE-------EEISKITARIGELKK---EIKELKKAIEELKkaKGKCPVCG 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 574 NglvcETMEEARHIALSgperqktvaldgtlflksgvisggssdlKYKARCWD-EKELKNLRDRRSQKIQELKGLMKTLR 652
Cdd:PRK03918 443 R----ELTEEHRKELLE----------------------------EYTAELKRiEKELKEIEEKERKLRKELRELEKVLK 490
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 653 KETDLKQIQTLIQgtqtRLKYSQNELEMIKKKHLVAFYQEQSQLQSELLNIESQCIMLSEGIKERQRRIKEFQEKIDKVE 732
Cdd:PRK03918 491 KESELIKLKELAE----QLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLD 566
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 733 DdifqhfCEEIGVENIREFENKHVKRQQEIDQKRLEFEKQKTRLnVQLEYSRSHLKKKLNKINTLKETIQKGSEDIDHLK 812
Cdd:PRK03918 567 E------LEEELAELLKELEELGFESVEELEERLKELEPFYNEY-LELKDAEKELEREEKELKKLEEELDKAFEELAETE 639
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 768024649 813 KAEENCLQTVNELMAKQQQlkdirvtqnSSAEKVQTQIEEERKKFLAVDREVGKLQKEVVSIQTSLEQKRLEKHNL 888
Cdd:PRK03918 640 KRLEELRKELEELEKKYSE---------EEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
128-464 |
6.28e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 53.99 E-value: 6.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 128 EEKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERYQSLLEELKM----NKIQLQLFQLYHNEKKIHLLNTKLEH 203
Cdd:PTZ00121 1363 EEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKaaaaKKKADEAKKKAEEKKKADEAKKKAEE 1442
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 204 VNR--DLSVKRESLSHHENIVK----ARKKEHGMLTRQLQQTEKELKSVETLLNQKRPQYIKAKE--NTSHHLKKLDVAK 275
Cdd:PTZ00121 1443 AKKadEAKKKAEEAKKAEEAKKkaeeAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEakKKADEAKKAEEAK 1522
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 276 KSIKDSEKQCSKQEDDI-KALETELADLDAAWRSFEKQIEEEILHKKRDIELEASQLDRYKELKEQVRKK----VATMTQ 350
Cdd:PTZ00121 1523 KADEAKKAEEAKKADEAkKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEArieeVMKLYE 1602
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 351 QLEKLQWEQ--KTDEERLAFEK-RRHGEVQGNLKQIKEQIEDHKKRIEKL---EEYTKTCMDCLKEKKQQEETLVDEIEK 424
Cdd:PTZ00121 1603 EEKKMKAEEakKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEELkkaEEENKIKAAEEAKKAEEDKKKAEEAKK 1682
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 768024649 425 TKSRMSEVNEELNLIRSELQNAGIDTHEGKRQQKRAEVLE 464
Cdd:PTZ00121 1683 AEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELK 1722
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
105-458 |
6.40e-07 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 53.87 E-value: 6.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 105 KKPKERTQFFEEISTSGELIGEYEEKKRKLQKAEEDAQFNFNKKKN------------IAAERRQAKLEKE--EAERYQS 170
Cdd:TIGR04523 149 KKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNkllklelllsnlKKKIQKNKSLESQisELKKQNN 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 171 LLE---ELKMNKIQLQLFQLYHNEKKIHLLNTKLEHVNRDLSVKRESLSHHENIVKArkkehgmLTRQLQQTEKELksvE 247
Cdd:TIGR04523 229 QLKdniEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKE-------LEKQLNQLKSEI---S 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 248 TLLNQKRPQYIKA-KENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEeilhKKRDIEL 326
Cdd:TIGR04523 299 DLNNQKEQDWNKElKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEE----KQNEIEK 374
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 327 EASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQGNLKQIKEQIEDHKKRIEKLEE------- 399
Cdd:TIGR04523 375 LKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNqdsvkel 454
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 768024649 400 YTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEELNLIRSELQNAGIDTHEGKRQQK 458
Cdd:TIGR04523 455 IIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVK 513
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
1083-1158 |
6.52e-07 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 50.32 E-value: 6.52e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 768024649 1083 LSGGEKCVAALALLFAvhsfRPAPFFVLDEVDAALDNTNIGKVSSYIKEQTQDQFQMIVISLKEEFYSRA-DALIGI 1158
Cdd:cd00267 81 LSGGQRQRVALARALL----LNPDLLLLDEPTSGLDPASRERLLELLRELAEEGRTVIIVTHDPELAELAaDRVIVL 153
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
259-730 |
6.69e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 53.62 E-value: 6.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 259 KAKENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAwrsfekqiEEEILHKKRDIELEASQLDRYKELk 338
Cdd:COG4717 64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAE--------LEELREELEKLEKLLQLLPLYQEL- 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 339 EQVRKKVATMTQQLEKLQWEQKTDEERLAfekrrhgevqgNLKQIKEQIEDHKKRIEKLEEYTKTcmdclkEKKQQEETL 418
Cdd:COG4717 135 EALEAELAELPERLEELEERLEELRELEE-----------ELEELEAELAELQEELEELLEQLSL------ATEEELQDL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 419 VDEIEKTKSRMSEVNEELNLIRSELQNAGIDTHEGKRQQKRAEVLEHLKRLYPDS-VFGRLFDLCHPIHKKYQLAVTkvF 497
Cdd:COG4717 198 AEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLlIAAALLALLGLGGSLLSLILT--I 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 498 GRFITAIVVASEKVAKDCIRFLKEERAEPETFLALDYLDIKPINERLRELKGCKMVIDVIKTQFPQLKKVIQFVCGNGLV 577
Cdd:COG4717 276 AGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLRE 355
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 578 CETMEEARHIALSGPERQKtvaldgtLFLKSGVISggSSDLKYKARCWDE-KELKNLRDRRSQKIQELKGLMKTLRKETD 656
Cdd:COG4717 356 AEELEEELQLEELEQEIAA-------LLAEAGVED--EEELRAALEQAEEyQELKEELEELEEQLEELLGELEELLEALD 426
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 768024649 657 LKQIQTLIQGTQTRLKYSQNELEMIKkkhlvafyQEQSQLQSELLNIESQcIMLSEGIKERQRRIKEFQEKIDK 730
Cdd:COG4717 427 EEELEEELEELEEELEELEEELEELR--------EELAELEAELEQLEED-GELAELLQELEELKAELRELAEE 491
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
153-390 |
7.83e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.77 E-value: 7.83e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 153 AERRQAKLE--KEEAERYQSLLEELKMNKIQLQLFQLYHNEKKIHLLNTKLEHVNRDLSVKRESLSHHENIVKARKKEHG 230
Cdd:COG4913 247 AREQIELLEpiRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELD 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 231 MLTRQLQQtekelksvetllnqkrpqyikakentsHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSfe 310
Cdd:COG4913 327 ELEAQIRG---------------------------NGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPA-- 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 311 kqiEEEILHKKRdiELEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQGNLKQIKEQIEDH 390
Cdd:COG4913 378 ---SAEEFAALR--AEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEA 452
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
234-446 |
2.12e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 51.30 E-value: 2.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 234 RQLQQTEKELKSVETLLNQKRPQYIKAKENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQI 313
Cdd:COG4942 27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 314 EE--------------EILHKKRDIELEASQLDRYKELKEQVRKKVATMTQQLEKLQweqktdeerlafekrrhgevqgn 379
Cdd:COG4942 107 AEllralyrlgrqpplALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA----------------------- 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 768024649 380 lkQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEELNLIRSELQNA 446
Cdd:COG4942 164 --ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
218-452 |
2.20e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 52.22 E-value: 2.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 218 HENIVKARKKEHgmLTRQLQQTEKELKSVETLLNQKRpqYIKAKENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALET 297
Cdd:COG4913 241 HEALEDAREQIE--LLEPIRELAERYAAARERLAELE--YLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEA 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 298 ELADLDAAWRSFEKQI-----------EEEILHKKRDieleasqldrykelKEQVRKKVATMTQQLEKLQWEQKTDEERL 366
Cdd:COG4913 317 RLDALREELDELEAQIrgnggdrleqlEREIERLERE--------------LEERERRRARLEALLAALGLPLPASAEEF 382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 367 AfekrrhgEVQGNLKQIKEQIEDHKKRIEklEEYTKTcMDCLKEKKQQEETLVDEIEKTKSRMSEVNEELNLIRSEL-QN 445
Cdd:COG4913 383 A-------ALRAEAAALLEALEEELEALE--EALAEA-EAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALaEA 452
|
....*..
gi 768024649 446 AGIDTHE 452
Cdd:COG4913 453 LGLDEAE 459
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
269-442 |
2.26e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 52.22 E-value: 2.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 269 KKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDA---AWRSFEKQIEEEIlhkkrDIELEASQLDRYKELKEQVRK-- 343
Cdd:COG4913 610 AKLAALEAELAELEEELAEAEERLEALEAELDALQErreALQRLAEYSWDEI-----DVASAEREIAELEAELERLDAss 684
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 344 -KVATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCM-DCLKEKKQQE------ 415
Cdd:COG4913 685 dDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELrALLEERFAAAlgdave 764
|
170 180 190
....*....|....*....|....*....|.
gi 768024649 416 ----ETLVDEIEKTKSRMSEVNEELNLIRSE 442
Cdd:COG4913 765 relrENLEERIDALRARLNRAEEELERAMRA 795
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
104-474 |
3.04e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.07 E-value: 3.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 104 VKKPKERTQFFEEISTSGELIGEYEEKKRKLQKAEEDAQfnfNKKKNIAAERRQAKLEKEEAERYQSLLEELKMNKIQlq 183
Cdd:PTZ00121 1301 KKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAE---EAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE-- 1375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 184 lfqlyhNEKKIHLLNTKLEHVNRDLSVKRESLSHHENIVKARKKEHG-MLTRQLQQTEKELKSVETLlnQKRPQYIKAKE 262
Cdd:PTZ00121 1376 ------AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAkKKADEAKKKAEEKKKADEA--KKKAEEAKKAD 1447
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 263 NTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADlDAAWRSFEKQIEEEILHKKRDIELEASQLDRYKELK--EQ 340
Cdd:PTZ00121 1448 EAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKAD-EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKkaDE 1526
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 341 VRK-KVATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQgNLKQIKEQIEDHKKRIEKLEEYTKTcmdclkEKKQQEETLV 419
Cdd:PTZ00121 1527 AKKaEEAKKADEAKKAEEKKKADELKKAEELKKAEEKK-KAEEAKKAEEDKNMALRKAEEAKKA------EEARIEEVMK 1599
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 768024649 420 DEIEKTKSRMSEVNEElnlirselQNAGIDTHEGKRQQKRAEVLEHLKRLYPDSV 474
Cdd:PTZ00121 1600 LYEEEKKMKAEEAKKA--------EEAKIKAEELKKAEEEKKKVEQLKKKEAEEK 1646
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
121-399 |
5.60e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.83 E-value: 5.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 121 GELIGEY-------EEKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERYQSLLEELKmnkiQLQLFQLYHNEKK 193
Cdd:PRK03918 451 KELLEEYtaelkriEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLK----KYNLEELEKKAEE 526
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 194 IHLLNTKLEHVNRDLSVKRESLSHheniVKARKKEHGMLTRQLQQTEKELKSVETLLNQKRPQYIKAKENTSHHLKK--- 270
Cdd:PRK03918 527 YEKLKEKLIKLKGEIKSLKKELEK----LEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPfyn 602
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 271 ----LDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEeiLHKKRDIELEASQLDRYKELkeqvRKKVA 346
Cdd:PRK03918 603 eyleLKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE--LEKKYSEEEYEELREEYLEL----SRELA 676
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 768024649 347 TMTQQLEKLQWEQKTDEERLAFEKRRHGEvqgnLKQIKEQIEDHKKRIEKLEE 399
Cdd:PRK03918 677 GLRAELEELEKRREEIKKTLEKLKEELEE----REKAKKELEKLEKALERVEE 725
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
714-1009 |
6.52e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 50.71 E-value: 6.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 714 IKERQRRIKEFQEKIDKVEDDIfqhfcEEIGvENIrefenKHVKRQQEIDQKRLEFEKQKTRLNVQLeysrshlkkKLNK 793
Cdd:COG1196 174 KEEAERKLEATEENLERLEDIL-----GELE-RQL-----EPLERQAEKAERYRELKEELKELEAEL---------LLLK 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 794 INTLKETIQKGSEDIDHLKKAEEnclqtvnELMAKQQQLKDIRVTQNSSAEKVQTQIEEERKKFLAVDREVGKLQKEVVS 873
Cdd:COG1196 234 LRELEAELEELEAELEELEAELE-------ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIAR 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 874 IQTSLEQKRLEKHNLLLDCKVQDIEIILLSGSLDDIIEVEMGTEAESTQATIDIYEKEEAFEIDYSSLKEDLKALQSDQE 953
Cdd:COG1196 307 LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 768024649 954 IEAHLRLLLQQVASQEDILLKTAAPNLRALENLKTVRDKFQESTDAFEASRKEARL 1009
Cdd:COG1196 387 ELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEE 442
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
115-428 |
2.44e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.98 E-value: 2.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 115 EEISTSGELIGEYEEKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERyqslLEELKMNKIQLQLFQLYHNE--K 192
Cdd:PTZ00121 1227 EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARK----ADELKKAEEKKKADEAKKAEekK 1302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 193 KIHLLNTKLEHVNRDLSVKRESLSHHENIVKARKK-EHGMLTRQLQQTEKELKSVETLLNQKRPQyiKAKENTSHHLKKL 271
Cdd:PTZ00121 1303 KADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKaEEAKKAAEAAKAEAEAAADEAEAAEEKAE--AAEKKKEEAKKKA 1380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 272 DVAKKSIKDSEK---------QCSKQEDDIKALETELADLDAAWRSFEKQIEEEILHKKRDielEASQLDRYKELKEQVR 342
Cdd:PTZ00121 1381 DAAKKKAEEKKKadeakkkaeEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAE---EAKKADEAKKKAEEAK 1457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 343 KkvatmTQQLEKlqweqKTDEERLAFEKRRHGEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEI 422
Cdd:PTZ00121 1458 K-----AEEAKK-----KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEA 1527
|
....*.
gi 768024649 423 EKTKSR 428
Cdd:PTZ00121 1528 KKAEEA 1533
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
219-400 |
2.67e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 48.23 E-value: 2.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 219 ENIVKARKKEHGMLTRQLQQTEKELKSVETLLNQKRpQYIKAKENTSHHLKKLDVAKKSIKDSEKQCSKQED------DI 292
Cdd:COG4717 56 DELFKPQGRKPELNLKELKELEEELKEAEEKEEEYA-ELQEELEELEEELEELEAELEELREELEKLEKLLQllplyqEL 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 293 KALETELADLDAAWRSFEKQIEE--EILHKKRDIELEASQLDR-----YKELKEQVRKKVATMTQQLEKLQWEQKTDEER 365
Cdd:COG4717 135 EALEAELAELPERLEELEERLEElrELEEELEELEAELAELQEeleelLEQLSLATEEELQDLAEELEELQQRLAELEEE 214
|
170 180 190
....*....|....*....|....*....|....*
gi 768024649 366 LAFEKRRHGEVQGNLKQIKEQIEDHKKRiEKLEEY 400
Cdd:COG4717 215 LEEAQEELEELEEELEQLENELEAAALE-ERLKEA 248
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
1079-1156 |
3.67e-05 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 46.06 E-value: 3.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 1079 PMDNLSGGEKCVAALALLFAVHSFRPA--PFFVLDEVDAALDNTNI-GKVSSYIKEQ-TQDQFQMIVISLKEEFYSRADA 1154
Cdd:cd03240 112 MRGRCSGGEKVLASLIIRLALAETFGSncGILALDEPTTNLDEENIeESLAEIIEERkSQKNFQLIVITHDEELVDAADH 191
|
..
gi 768024649 1155 LI 1156
Cdd:cd03240 192 IY 193
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
105-445 |
4.33e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.21 E-value: 4.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 105 KKPKERTQFFEEISTSGELIGEYEEKKRK---LQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERYQSL--LEELKMNK 179
Cdd:PTZ00121 1470 KKADEAKKKAEEAKKADEAKKKAEEAKKKadeAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAkkAEEKKKAD 1549
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 180 IQLQLFQLYHNEKKIHLLNTKLEHVNRDLSVKRESLShhENIVKARKKEHGMLTRQLQQTEKELKSVETLLNQKRPQYIK 259
Cdd:PTZ00121 1550 ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEA--KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK 1627
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 260 AKENTSHHLKKLDVAKKSIKDSEkQCSKQEDDIKALETELADLDAAwrsfEKQIEEEILHKKRDIELEASQLDRYKELK- 338
Cdd:PTZ00121 1628 AEEEKKKVEQLKKKEAEEKKKAE-ELKKAEEENKIKAAEEAKKAEE----DKKKAEEAKKAEEDEKKAAEALKKEAEEAk 1702
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 339 --EQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEE 416
Cdd:PTZ00121 1703 kaEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE 1782
|
330 340
....*....|....*....|....*....
gi 768024649 417 TLVDeiEKTKSRMSEVNEELNLIRSELQN 445
Cdd:PTZ00121 1783 EELD--EEDEKRRMEVDKKIKDIFDNFAN 1809
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
127-464 |
4.50e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 47.89 E-value: 4.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 127 YEEKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERYQSLLEElKMNKIQLQLF----QLYHNEKKIHLLNTKLE 202
Cdd:pfam10174 354 LEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQK-KIENLQEQLRdkdkQLAGLKERVKSLQTDSS 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 203 HVNRDLSVKRESLSHHENIVKARKKEHGMLTRQ----LQQTEKELKSVETLLNQKRPQ-------YIKAKENTSHHLKKL 271
Cdd:pfam10174 433 NTDTALTTLEEALSEKERIIERLKEQREREDRErleeLESLKKENKDLKEKVSALQPEltekessLIDLKEHASSLASSG 512
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 272 DVAKKSIKDSEKQCSKQEDDIKALETELadLDAAWRSFEKQIEEEILHKKRDIELEASqldRYKELKEQVRKKVATMTQQ 351
Cdd:pfam10174 513 LKKDSKLKSLEIAVEQKKEECSKLENQL--KKAHNAEEAVRTNPEINDRIRLLEQEVA---RYKEESGKAQAEVERLLGI 587
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 352 LEKLQWEQKTDEERLA-FEK---RRHGEVQGNLKQIKE-QIEDHKKRIEKLEEYTKTCMDCL-KEKKQQEETLVDEIEKT 425
Cdd:pfam10174 588 LREVENEKNDKDKKIAeLESltlRQMKEQNKKVANIKHgQQEMKKKGAQLLEEARRREDNLAdNSQQLQLEELMGALEKT 667
|
330 340 350
....*....|....*....|....*....|....*....
gi 768024649 426 KSRMSEVNEELNLIRSELQNAgiDTHEGKRQQKRAEVLE 464
Cdd:pfam10174 668 RQELDATKARLSSTQQSLAEK--DGHLTNLRAERRKQLE 704
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
710-1009 |
6.38e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 47.24 E-value: 6.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 710 LSEGIKERQ-----RRIKEFQEKIDKVEDDIfqhfceEIGVENIREFENKHVKRQQEIDQKRLEFEKQKTRLNVQLEysr 784
Cdd:COG1196 218 LKEELKELEaelllLKLRELEAELEELEAEL------EELEAELEELEAELAELEAELEELRLELEELELELEEAQA--- 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 785 shlkkklnKINTLKETIQKGSEDIDHLKKAEENCLQTVNELMAKQQQLKDIRVTQNSSAEKVQTQIEEERKKFLAVDREV 864
Cdd:COG1196 289 --------EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAEL 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 865 GKLQKEVVSIQTSLEQKRLEKHNL---LLDCKVQDIEIILLSGSLDDIIEVEMGTEAESTQATIDIYEKEEAFEIDYSSL 941
Cdd:COG1196 361 AEAEEALLEAEAELAEAEEELEELaeeLLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE 440
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768024649 942 KEDLKA-------LQSDQEIEAHLRLLLQQVASQEDILLKTAAPNLRALENLKTVRDKFQESTDAFEASRKEARL 1009
Cdd:COG1196 441 EEALEEaaeeeaeLEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALL 515
|
|
| ABC_SMC6_euk |
cd03276 |
ATP-binding cassette domain of eukaryotic SM6 proteins; The structural maintenance of ... |
1080-1121 |
7.36e-05 |
|
ATP-binding cassette domain of eukaryotic SM6 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213243 [Multi-domain] Cd Length: 198 Bit Score: 45.28 E-value: 7.36e-05
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 768024649 1080 MDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTN 1121
Cdd:cd03276 107 VKTLSGGERSFSTVCLLLSLWEVMESPFRCLDEFDVFMDMVN 148
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
733-1158 |
1.90e-04 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 45.66 E-value: 1.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 733 DDIFQHFCEEIG--VENIREFENKhvkrQQEIDQKRLEFEKQKTRLNV-----------QLEYSRSHLKKKLNKINTLKE 799
Cdd:PRK01156 468 NHIINHYNEKKSrlEEKIREIEIE----VKDIDEKIVDLKKRKEYLESeeinksineynKIESARADLEDIKIKINELKD 543
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 800 TIQKGSEDIDHLKKAEENCLQTVNElmakqQQLKDIRVTQNSSAEKVQTQIEEERKKFLAVDREVGKLQKEVVSIQTSLE 879
Cdd:PRK01156 544 KHDKYEEIKNRYKSLKLEDLDSKRT-----SWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYID 618
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 880 Q--KRLEKHNLLLDCKVQDIE-----IILLSGSLDDIIEVEMGT-EAESTQATIDIyeKEEAFEIDYSSLKEDLKALQSD 951
Cdd:PRK01156 619 KsiREIENEANNLNNKYNEIQenkilIEKLRGKIDNYKKQIAEIdSIIPDLKEITS--RINDIEDNLKKSRKALDDAKAN 696
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 952 Q-EIEAHLRLLLQQVASQEDIL------LKTAAPNLRALENLKTVRDKFqeSTDAFEAS-RKEArlcrQEFEQVKKRRYd 1023
Cdd:PRK01156 697 RaRLESTIEILRTRINELSDRIndinetLESMKKIKKAIGDLKRLREAF--DKSGVPAMiRKSA----SQAMTSLTRKY- 769
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 1024 LFTQCFEHVSISIDQIYK-KLCRNNSAQAflspenpeepylegisyncvapgkrfmpMDNLSGGEKCVAALALLFAVHSF 1102
Cdd:PRK01156 770 LFEFNLDFDDIDVDQDFNiTVSRGGMVEG----------------------------IDSLSGGEKTAVAFALRVAVAQF 821
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 768024649 1103 RPA--PFFVLDEVDAALDN---TNIGKVSSYIKEQTQDQFQMIVISLKEEFYSRADALIGI 1158
Cdd:PRK01156 822 LNNdkSLLIMDEPTAFLDEdrrTNLKDIIEYSLKDSSDIPQVIMISHHRELLSVADVAYEV 882
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
191-881 |
2.59e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 45.34 E-value: 2.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 191 EKKIHLLN-TKLEHVNRDLSVKRE---SLSHHENIVKARKKEHGMLTRQLQQTEKELKSVETLLNQKRPQYIKAKENTSH 266
Cdd:TIGR00618 164 EKKELLMNlFPLDQYTQLALMEFAkkkSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHA 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 267 HLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAW--RSFEKQIEEEILHKKRDIELEASQLDRYKELKEQVRKK 344
Cdd:TIGR00618 244 YLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQerINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSR 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 345 VATMTQQLEKLQWEQKTDEERLAFEK--------RRHGEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEE 416
Cdd:TIGR00618 324 AKLLMKRAAHVKQQSSIEEQRRLLQTlhsqeihiRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELD 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 417 TLVDEIEKTKSRMSEVN-EELNLIRSELQNAGIDTHEGKRQQKRAEVLEHLKRLYPDSVfgRLFDLCHpiHKKYQLAVTK 495
Cdd:TIGR00618 404 ILQREQATIDTRTSAFRdLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQ--ESAQSLK--EREQQLQTKE 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 496 VfgrfitaIVVASEKVAKDCIRFLKEERAEPetflaldyldiKPINERLRELKGCKMVIDVIKTQFPQLKKVIQFVCGNG 575
Cdd:TIGR00618 480 Q-------IHLQETRKKAVVLARLLELQEEP-----------CPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLE 541
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 576 lvcETMEEARHIALSGPERQKTvaldgtlflksgvisggssdLKYKARCWDEKELKnlrdrRSQKIQELKGLMKTLRKET 655
Cdd:TIGR00618 542 ---TSEEDVYHQLTSERKQRAS--------------------LKEQMQEIQQSFSI-----LTQCDNRSKEDIPNLQNIT 593
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 656 DLKQIQTLIQGTQTRLKYSQNELEMIKKKHLVAFYQ--------EQSQLQSELLNIESQCIMLSEGIKERQRRIKEFQE- 726
Cdd:TIGR00618 594 VRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDvrlhlqqcSQELALKLTALHALQLTLTQERVREHALSIRVLPKe 673
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 727 -------KIDKVEDDIFQHFCEEIGVENIREFENKHVKRQQEIDQKRLEFEKQKTRLNVQLEYSRSHLKKKLNKINTLKE 799
Cdd:TIGR00618 674 llasrqlALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQAR 753
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 800 TIQKGSEDIDHLKK----AEENCLQTVNELMAKQQQLKDIRVTQNSSAEKVQTQIEEERKKFL-AVDREVGKLQKEVVSI 874
Cdd:TIGR00618 754 TVLKARTEAHFNNNeevtAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEdILNLQCETLVQEEEQF 833
|
....*..
gi 768024649 875 QTSLEQK 881
Cdd:TIGR00618 834 LSRLEEK 840
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
638-882 |
2.81e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.75 E-value: 2.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 638 SQKIQELKGLMKTLRKEtdLKQIQTLIQGTQTRLKYSQNELEMIKKKhlvafyqeQSQLQSELLNIESQCIMLSEGIKER 717
Cdd:COG4942 19 ADAAAEAEAELEQLQQE--IAELEKELAALKKEEKALLKQLAALERR--------IAALARRIRALEQELAALEAELAEL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 718 QRRIKEFQEKIDKVEDDIFQHFceeigvenirefenkhVKRQQEIDQKRLEF---EKQKTRLNVQLEYSRSHLKKKLNKI 794
Cdd:COG4942 89 EKEIAELRAELEAQKEELAELL----------------RALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 795 NTLKETIQKGSEDIDHLKKAEENCLQTVNELMAKQQQLKDIRVTQNSSAEKVQTQIEEERKKFLAVDREVGKLQKEVVSI 874
Cdd:COG4942 153 EELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232
|
....*...
gi 768024649 875 QTSLEQKR 882
Cdd:COG4942 233 EAEAAAAA 240
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
129-416 |
3.00e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 45.11 E-value: 3.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 129 EKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKE-EAERYQSL-----LEELKMNKIQLQLFQLYHNEKKIHLLNTKLE 202
Cdd:pfam17380 313 ERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERErELERIRQEerkreLERIRQEEIAMEISRMRELERLQMERQQKNE 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 203 HVNRDLSVKREslshheniVKARKKEHgmlTRQLQQTEKELKSVETLLNQKRPQYIKA-KENTSHHLKKLDVAKKSIKDS 281
Cdd:pfam17380 393 RVRQELEAARK--------VKILEEER---QRKIQQQKVEMEQIRAEQEEARQREVRRlEEERAREMERVRLEEQERQQQ 461
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 282 EKQCSKQEDDIKALETELADldaawRSFEKQIEEEILHKKRDIELEAsqldRYKELKEQVRKKVATMTQQLEKLQWEQKT 361
Cdd:pfam17380 462 VERLRQQEEERKRKKLELEK-----EKRDRKRAEEQRRKILEKELEE----RKQAMIEEERKRKLLEKEMEERQKAIYEE 532
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 768024649 362 DEERLAFEKRRHGEVQGNLKQIKEQI---EDHKKRIEKLEEYTKTCMDCLKEKKQQEE 416
Cdd:pfam17380 533 ERRREAEEERRKQQEMEERRRIQEQMrkaTEERSRLEAMEREREMMRQIVESEKARAE 590
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
96-468 |
3.32e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 45.04 E-value: 3.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 96 QGTVESISVKKPKERTQFFEEISTSGELIG----EYEEKKRKLQKAEEDAQfnfNKKKNIAAERRQAKLEKEEAERYQSL 171
Cdd:TIGR00606 711 LKSTESELKKKEKRRDEMLGLAPGRQSIIDlkekEIPELRNKLQKVNRDIQ---RLKNDIEEQETLLGTIMPEEESAKVC 787
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 172 LEELKMnkIQLQLFQLYHNEKKIHLLNTKLEHVNRDLSVKRESLSHHENIVKARK-KEHGMLTRQLQQTEkelksvetll 250
Cdd:TIGR00606 788 LTDVTI--MERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTvVSKIELNRKLIQDQ---------- 855
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 251 nQKRPQYIKAKENtshhlkKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEEILHKKRDIELEASQ 330
Cdd:TIGR00606 856 -QEQIQHLKSKTN------ELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEEL 928
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 331 LDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRH-GEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCMDCLK 409
Cdd:TIGR00606 929 ISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYlKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDID 1008
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 768024649 410 EKKQQEETLVDEIEKTKSR--MSEVNEELNLIRSELQNAGIdTHEGKRQQKRAEVLEHLKR 468
Cdd:TIGR00606 1009 TQKIQERWLQDNLTLRKREneLKEVEEELKQHLKEMGQMQV-LQMKQEHQKLEENIDLIKR 1068
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
625-888 |
3.44e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.01 E-value: 3.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 625 WDEKELKNLrdrrSQKIQELKGLMKTLrkETDLKQIQTLIQGTQTRLKYSQNELEMIKKK--HLVAFYQEQSQLQSELLN 702
Cdd:TIGR04523 149 KKEKELEKL----NNKYNDLKKQKEEL--ENELNLLEKEKLNIQKNIDKIKNKLLKLELLlsNLKKKIQKNKSLESQISE 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 703 IESQCIMLSEGIKERQRRIKEFQEKIDKVEDDIFQHFCEEIgvENIREFENKhvkrQQEIDQ---KRLEFEKQKTRLNVQ 779
Cdd:TIGR04523 223 LKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQN--KIKKQLSEK----QKELEQnnkKIKELEKQLNQLKSE 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 780 LEYSRShlKKKLNKINTLKETIQKGSEDIDHLKKAEENCLQTVNELMAKQQQLKDIRVTQNSSAEKVQTQIEEERKkfla 859
Cdd:TIGR04523 297 ISDLNN--QKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQN---- 370
|
250 260
....*....|....*....|....*....
gi 768024649 860 vdrEVGKLQKEVVSIQTSLEQKRLEKHNL 888
Cdd:TIGR04523 371 ---EIEKLKKENQSYKQEIKNLESQINDL 396
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
126-443 |
4.11e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 44.63 E-value: 4.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 126 EYEEKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERYQSLLEElKMNKIQLQLFQLyHNEKK---IHLLNTKLE 202
Cdd:TIGR04523 240 EINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEK-QLNQLKSEISDL-NNQKEqdwNKELKSELK 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 203 HVNRDLSVKRESLSHHENIVKARKKEHGMLTRQLQQTEKELKSVETLLNQKRPQYIKAKENTSHHLKKLDVAKKSIKDSE 282
Cdd:TIGR04523 318 NQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLE 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 283 KQCSKQEDDIKALETELADLDAAWRSFEKQIEEeilhKKRDIELEASQLDRYKELKEQVRKKVatmtQQLEKLQWEQKTD 362
Cdd:TIGR04523 398 SKIQNQEKLNQQKDEQIKKLQQEKELLEKEIER----LKETIIKNNSEIKDLTNQDSVKELII----KNLDNTRESLETQ 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 363 EERLafeKRRHGEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEELNLIRSE 442
Cdd:TIGR04523 470 LKVL---SRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDE 546
|
.
gi 768024649 443 L 443
Cdd:TIGR04523 547 L 547
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
1009-1161 |
4.74e-04 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 42.31 E-value: 4.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 1009 LCRQEFEQVKKRRYDLFTQCFEHVS-ISIDQIyKKLCRNnsaqaflspenpeepyleGISYncVAPGKrfmPMDNLSGGE 1087
Cdd:cd03238 37 LVNEGLYASGKARLISFLPKFSRNKlIFIDQL-QFLIDV------------------GLGY--LTLGQ---KLSTLSGGE 92
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 768024649 1088 KCVAALALLFAVHSFRPapFFVLDEVDAALDNTNIGKVSSYIKEQTQDQFQMIVISLKEEFYSRADALIGIYPE 1161
Cdd:cd03238 93 LQRVKLASELFSEPPGT--LFILDEPSTGLHQQDINQLLEVIKGLIDLGNTVILIEHNLDVLSSADWIIDFGPG 164
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
118-442 |
5.00e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 44.24 E-value: 5.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 118 STSGELIGEYEEKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERYQSLLEElKMNKIQLQLFQLYHNEKKIHLL 197
Cdd:TIGR04523 356 SENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDE-QIKKLQQEKELLEKEIERLKET 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 198 NTKLEHVNRDL----SVKRESLSHHENIVKARKKEHGMLTRQ-------LQQTEKELKSVETLLNQKRPQYIKAKENTSH 266
Cdd:TIGR04523 435 IIKNNSEIKDLtnqdSVKELIIKNLDNTRESLETQLKVLSRSinkikqnLEQKQKELKSKEKELKKLNEEKKELEEKVKD 514
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 267 HLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSfeKQIEEEILHKKRDIE--------LEASQlDRYKELK 338
Cdd:TIGR04523 515 LTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKK--ENLEKEIDEKNKEIEelkqtqksLKKKQ-EEKQELI 591
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 339 EQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETL 418
Cdd:TIGR04523 592 DQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKES 671
|
330 340
....*....|....*....|....
gi 768024649 419 VDEIEKTKSRMSEVNEELNLIRSE 442
Cdd:TIGR04523 672 KTKIDDIIELMKDWLKELSLHYKK 695
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
128-424 |
5.25e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 44.44 E-value: 5.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 128 EEKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERYQSL-LEELKMNKIQL-QLFQLYHNEKKihllnTKLEHVN 205
Cdd:pfam12128 600 EELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFaRTALKNARLDLrRLFDEKQSEKD-----KKNKALA 674
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 206 RDLSVKRESLSHHENIVKARKKEHGMLtrqLQQTEKELKSVETLLNQKRPQYIKAKENTSHHLKK-LDVAKKSIKDSEKQ 284
Cdd:pfam12128 675 ERKDSANERLNSLEAQLKQLDKKHQAW---LEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAaIAARRSGAKAELKA 751
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 285 CSKQED-DIKAL---ETELADLDAAWRSFEKQIEE------EILHKKRDI-ELEASQLDRYKELKEQVRKKVATMTQQLE 353
Cdd:pfam12128 752 LETWYKrDLASLgvdPDVIAKLKREIRTLERKIERiavrrqEVLRYFDWYqETWLQRRPRLATQLSNIERAISELQQQLA 831
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 354 KLQWEQKTDeeRLAFEKRRHG------EVQGNLKQIKEQIE-----DHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEI 422
Cdd:pfam12128 832 RLIADTKLR--RAKLEMERKAsekqqvRLSENLRGLRCEMSklatlKEDANSEQAQGSIGERLAQLEDLKLKRDYLSESV 909
|
..
gi 768024649 423 EK 424
Cdd:pfam12128 910 KK 911
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
108-444 |
5.34e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 44.28 E-value: 5.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 108 KERTQFFEEISTSGELIGEYEEKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERYQSLLEELKMNKIQLQLFQL 187
Cdd:PRK03918 300 EFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKK 379
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 188 YHNEKKIHLLNTKLEHVNRdlsvKRESLSHHENIVKARKkehgmltRQLQQTEKEL-KSVETLLNQKRPQYIKAKENTSH 266
Cdd:PRK03918 380 RLTGLTPEKLEKELEELEK----AKEEIEEEISKITARI-------GELKKEIKELkKAIEELKKAKGKCPVCGRELTEE 448
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 267 HLKKLdvakksIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEEilhkkrdieleaSQLDRYKELKEQVRKkva 346
Cdd:PRK03918 449 HRKEL------LEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKE------------SELIKLKELAEQLKE--- 507
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 347 tMTQQLEKLqweqktDEERLAFEKRRHGEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTK 426
Cdd:PRK03918 508 -LEEKLKKY------NLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELE 580
|
330
....*....|....*...
gi 768024649 427 SRMSEVNEELNLIRSELQ 444
Cdd:PRK03918 581 ELGFESVEELEERLKELE 598
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
142-360 |
5.53e-04 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 43.96 E-value: 5.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 142 QFNFNKKKNIAAERRQAKLEKEEAERYQSLLEELKMNKIQLQlfqlyhnekkihllntKLEHVNRDLSVKRESLSHHENI 221
Cdd:pfam05557 42 QLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKK----------------YLEALNKKLNEKESQLADAREV 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 222 VKARKKEHGMLTRQLQQTEKELKSVET----------LLNQKRPQYIKAKENTSHHLKKLDVAKKSIKDSEKQCSKQEDD 291
Cdd:pfam05557 106 ISCLKNELSELRRQIQRAELELQSTNSeleelqerldLLKAKASEAEQLRQNLEKQQSSLAEAEQRIKELEFEIQSQEQD 185
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 768024649 292 ---IKALETELADLdAAWRSFEKQIEEEILH---KKRDIELEASQLDRYK---ELKEQVRKKVATMTQQLEKLQWEQK 360
Cdd:pfam05557 186 seiVKNSKSELARI-PELEKELERLREHNKHlneNIENKLLLKEEVEDLKrklEREEKYREEAATLELEKEKLEQELQ 262
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
122-468 |
5.91e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 44.28 E-value: 5.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 122 ELIGEYEEKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERYQSLLEELKMNKIQLQlfqlyhnekKIHLLNTKL 201
Cdd:PRK03918 235 ELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYI---------KLSEFYEEY 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 202 EHVNRDLSVKRESLSHHENIVKARKKEHGMLTRQLQQTEKELKSVETLLNQKRP-----QYIKAKENTSHHLKK------ 270
Cdd:PRK03918 306 LDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEErhelyEEAKAKKEELERLKKrltglt 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 271 LDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEEILHKKR--------DIELEASQLDRYKELKEQVR 342
Cdd:PRK03918 386 PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgrelTEEHRKELLEEYTAELKRIE 465
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 343 KKVATMTQQLEKLQWEQKTDEERLAFEKRRHgevqgNLKQIKEQIEDHKKRIEKLEeytktcmdclkekkqqeetlVDEI 422
Cdd:PRK03918 466 KELKEIEEKERKLRKELRELEKVLKKESELI-----KLKELAEQLKELEEKLKKYN--------------------LEEL 520
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 768024649 423 EKTKSRMSEVNEELNLIRSELQNAGIDTHEGKRQQKRAEVLEHLKR 468
Cdd:PRK03918 521 EKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLD 566
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
216-450 |
6.78e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 43.85 E-value: 6.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 216 SHHENIVKARKKEHGMLTR------QLQQTEKELKSVETLLNQKRPQYIKAKENTSHHLKKLDVAKKSIKDSEKQCSKqe 289
Cdd:PHA02562 199 TYNKNIEEQRKKNGENIARkqnkydELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQK-- 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 290 ddikaleteladldaawrsfekqiEEEILHKKRDIELEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEER---L 366
Cdd:PHA02562 277 ------------------------VIKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEImdeF 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 367 AFEKRRHGEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEE---LNLIRSEL 443
Cdd:PHA02562 333 NEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEkyhRGIVTDLL 412
|
....*..
gi 768024649 444 QNAGIDT 450
Cdd:PHA02562 413 KDSGIKA 419
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
108-469 |
8.89e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.60 E-value: 8.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 108 KERTQFFEEISTSGELIGEYEEKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERYQSLLE-ELKMNKIQLQLFQ 186
Cdd:COG4717 71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEAlEAELAELPERLEE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 187 LYHNEKKIHLLNTKLEHVNRDLSVKRESLSHHENIVKARKKEhgmltrQLQQTEKELKSVETLLNQKRPQYIKAKENTSH 266
Cdd:COG4717 151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEE------ELQDLAEELEELQQRLAELEEELEEAQEELEE 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 267 HLKKLD-VAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEE--------------EILHKKRDIELEASQL 331
Cdd:COG4717 225 LEEELEqLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTiagvlflvlgllalLFLLLAREKASLGKEA 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 332 DRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQGNLKQIKEQIEDHkkrieKLEEYTKTCMDCLKEK 411
Cdd:COG4717 305 EELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL-----QLEELEQEIAALLAEA 379
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 768024649 412 KQQEETLVDEIEKTKSRMSEVNEELNLIRSELQNAGIDTHEGKRQQKRAEVLEHLKRL 469
Cdd:COG4717 380 GVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEEL 437
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
283-446 |
9.79e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 43.57 E-value: 9.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 283 KQCSKQEDDIKALETELADldaAWRSFEKQIEEeilhKKRDIELEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTD 362
Cdd:pfam15921 317 RQLSDLESTVSQLRSELRE---AKRMYEDKIEE----LEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKR 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 363 EERLAFEKRRHGEV----QGN---LKQIKEQIEDHKKRIEKLEEYTKTCM-DCLKEKKQQE-------------ETLVDE 421
Cdd:pfam15921 390 EKELSLEKEQNKRLwdrdTGNsitIDHLRRELDDRNMEVQRLEALLKAMKsECQGQMERQMaaiqgkneslekvSSLTAQ 469
|
170 180
....*....|....*....|....*
gi 768024649 422 IEKTKSRMSEVNEELNLIRSELQNA 446
Cdd:pfam15921 470 LESTKEMLRKVVEELTAKKMTLESS 494
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
122-445 |
1.08e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 43.13 E-value: 1.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 122 ELIGEYEEKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERY-----QSLLEELKMNKIQLQLFQLYHNEKKIHL 196
Cdd:PRK03918 391 KELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgRELTEEHRKELLEEYTAELKRIEKELKE 470
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 197 LNTKLEHVNRDLSVKRESLSHHENIVKARKkehgmLTRQLQQTEKELKSVET-LLNQKRPQYIKAKENtshhLKKLDVAK 275
Cdd:PRK03918 471 IEEKERKLRKELRELEKVLKKESELIKLKE-----LAEQLKELEEKLKKYNLeELEKKAEEYEKLKEK----LIKLKGEI 541
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 276 KSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEEILHKKRDIELEASQL----DRYKELKEqVRKKVATMTQQ 351
Cdd:PRK03918 542 KSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELepfyNEYLELKD-AEKELEREEKE 620
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 352 LEKLQWEQKTDEERLAFEKRRHGEVQGNLKQIKEQI--EDHKKRIEKLEEYTKTcMDCLKEKKQQEETLVDEIEKTKSRM 429
Cdd:PRK03918 621 LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYseEEYEELREEYLELSRE-LAGLRAELEELEKRREEIKKTLEKL 699
|
330
....*....|....*.
gi 768024649 430 SEVNEELNLIRSELQN 445
Cdd:PRK03918 700 KEELEEREKAKKELEK 715
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
122-469 |
1.23e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 43.13 E-value: 1.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 122 ELIGEYEEKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERYQSLLEELK-----MNKIQLQLFQLYHNEKKIHL 196
Cdd:PRK03918 218 ELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKkeieeLEEKVKELKELKEKAEEYIK 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 197 LN---TKLEHVNRDLSVKRESLSHHENIVKARKKEHGMLTRQLQQTEKELKSVETLLNQKRP-----QYIKAKENTSHHL 268
Cdd:PRK03918 298 LSefyEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEErhelyEEAKAKKEELERL 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 269 KK------LDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEEILHKKR--------DIELEASQLDRY 334
Cdd:PRK03918 378 KKrltgltPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgrelTEEHRKELLEEY 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 335 KELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHgevqgNLKQIKEQIEDHKkriEKLEEYTKtcmDCLKEKKQQ 414
Cdd:PRK03918 458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELI-----KLKELAEQLKELE---EKLKKYNL---EELEKKAEE 526
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 768024649 415 EETLVDEIEKTKSRMSEVNEELNLIRS-ELQNAGIDTHEGKRQQKRAEVLEHLKRL 469
Cdd:PRK03918 527 YEKLKEKLIKLKGEIKSLKKELEKLEElKKKLAELEKKLDELEEELAELLKELEEL 582
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
177-345 |
1.42e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.83 E-value: 1.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 177 MNKIQLQLFQLYHNEKKIHLLNTKLEHVNRDLSVKRESLSHHENIVKARKKEHGMLTRQLQQTEKELKSVETLLNQKRPQ 256
Cdd:COG1579 2 MPEDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 257 YIKAKENT--SHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEEIlhKKRDIELEA--SQLD 332
Cdd:COG1579 82 LGNVRNNKeyEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKK--AELDEELAEleAELE 159
|
170
....*....|...
gi 768024649 333 RYKELKEQVRKKV 345
Cdd:COG1579 160 ELEAEREELAAKI 172
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
716-885 |
1.50e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 42.80 E-value: 1.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 716 ERQRRIKEFQEKIDKVEDDIFQHfcEEIGVE--NIREFENKHVKRQQEIDQKRLEFEKQKTRLNVQLEYSRSHLKKKLNK 793
Cdd:pfam17380 345 ERERELERIRQEERKRELERIRQ--EEIAMEisRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEM 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 794 INTLKETIQKGSEDIDHLKKAEENCLQTVN-ELMAKQQQLKDIRVTQNSSAEKVQTQIEEERKKFLAVDREVGKLQKEV- 871
Cdd:pfam17380 423 EQIRAEQEEARQREVRRLEEERAREMERVRlEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELe 502
|
170
....*....|....
gi 768024649 872 VSIQTSLEQKRLEK 885
Cdd:pfam17380 503 ERKQAMIEEERKRK 516
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
204-469 |
1.57e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 42.72 E-value: 1.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 204 VNRDLSVKRESLSHHENIVKArkKEHGMLTRQLQQTEKELKSVETLL---NQKRPQYIKAKENTSHHLKKLDVAKKSIKD 280
Cdd:PRK02224 178 VERVLSDQRGSLDQLKAQIEE--KEEKDLHERLNGLESELAELDEEIeryEEQREQARETRDEADEVLEEHEERREELET 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 281 SEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEeiLHKKRDIELEASQLDRYkelkeqvrkkvatmtqqleklqwEQK 360
Cdd:PRK02224 256 LEAEIEDLRETIAETEREREELAEEVRDLRERLEE--LEEERDDLLAEAGLDDA-----------------------DAE 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 361 TDEERLAFEKRRHGEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEELNLIR 440
Cdd:PRK02224 311 AVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELE 390
|
250 260 270
....*....|....*....|....*....|....
gi 768024649 441 SELQN-----AGIDTHEGKRQQKRAEVLEHLKRL 469
Cdd:PRK02224 391 EEIEElrerfGDAPVDLGNAEDFLEELREERDEL 424
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
189-882 |
1.63e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 42.80 E-value: 1.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 189 HNEKKIHL------LNTKLEhvnrDLSVKRESLShheNIVKARKKEHGMLTRQLQQTEKELKSV----ETLLNQKRPQYI 258
Cdd:pfam15921 101 HEKQKFYLrqsvidLQTKLQ----EMQMERDAMA---DIRRRESQSQEDLRNQLQNTVHELEAAkclkEDMLEDSNTQIE 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 259 KAKENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALET-ELADLDAAWRSFEKQIEEEILH-KKRDIELEasqlDRYKE 336
Cdd:pfam15921 174 QLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTmHFRSLGSAISKILRELDTEISYlKGRIFPVE----DQLEA 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 337 LKEQVRKKVATMTQQ----LEKLQWEQKTD----EERLAFEKRRHGEVQGNLKQIKEQIED----HKKRIEKLEEYTKTC 404
Cdd:pfam15921 250 LKSESQNKIELLLQQhqdrIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQEQARNqnsmYMRQLSDLESTVSQL 329
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 405 MDCLKEKKQQEETLVDEIEKtksrmsevneELNLIRSELQNAgiDTHEGKRQQKRAEVLEHLKRLYPDsvfgrlfdlchp 484
Cdd:pfam15921 330 RSELREAKRMYEDKIEELEK----------QLVLANSELTEA--RTERDQFSQESGNLDDQLQKLLAD------------ 385
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 485 IHKKyqlavtkvfgrfitaivvasEKVakdcirfLKEERAEPETFLALDYLDIKPINERLRELKGCKMVIDVIKTQFPQL 564
Cdd:pfam15921 386 LHKR--------------------EKE-------LSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAM 438
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 565 KKViqfvcgnglvCETMEEARHIALSGperqKTVALDGTLFLKSgvisggssdlkykarcwdekELKNLRDRRSQKIQEL 644
Cdd:pfam15921 439 KSE----------CQGQMERQMAAIQG----KNESLEKVSSLTA--------------------QLESTKEMLRKVVEEL 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 645 KGLMKTLRK-ETDLKQIQTLIQGTQTRLKYSQNELEMIKKKHLVAFyQEQSQLQSE---LLNIESQCIMLSEGIKERQRR 720
Cdd:pfam15921 485 TAKKMTLESsERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKL-QELQHLKNEgdhLRNVQTECEALKLQMAEKDKV 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 721 IKEFQEKIDKVEDDIFQHFceeigvENIREFENKHVKRQQEIDQKRLEFEKQKTrLNVQLEYSRSHLKKKLNKINTLK-E 799
Cdd:pfam15921 564 IEILRQQIENMTQLVGQHG------RTAGAMQVEKAQLEKEINDRRLELQEFKI-LKDKKDAKIRELEARVSDLELEKvK 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 800 TIQKGSEDIDHLKKAEENCLQTVNELMAKQQQLkdirvtqNSSAEKVQTQIEEERKKFLAVDREVGKLQKEVVSIQTSLE 879
Cdd:pfam15921 637 LVNAGSERLRAVKDIKQERDQLLNEVKTSRNEL-------NSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELE 709
|
...
gi 768024649 880 QKR 882
Cdd:pfam15921 710 QTR 712
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
112-364 |
1.79e-03 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 42.69 E-value: 1.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 112 QFFEEISTSGELIGEYE------EKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAeryqslleELKMNKIQLQLF 185
Cdd:NF033838 129 QFKKDTLEPGKKVAEATkkveeaEKKAKDQKEEDRRNYPTNTYKTLELEIAESDVEVKKA--------ELELVKEEAKEP 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 186 QlyhNEKKIHLLNTKLEHvnrdlsvKRESLSHHENIVKARKKEHGMLTRQLQQTEKEL--KSVETLLNQKRPQYIK---- 259
Cdd:NF033838 201 R---DEEKIKQAKAKVES-------KKAEATRLEKIKTDREKAEEEAKRRADAKLKEAveKNVATSEQDKPKRRAKrgvl 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 260 -------AKENTSHHL-----------------KKLDVAKKSIKDSEKQCSKQEDD---------IKALETELADLDAAW 306
Cdd:NF033838 271 gepatpdKKENDAKSSdssvgeetlpspslkpeKKVAEAEKKVEEAKKKAKDQKEEdrrnyptntYKTLELEIAESDVKV 350
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 768024649 307 RSFEKQIEEEILHKKRDIEleasqldRYKELKEQVRKKVATMTqQLEKLQWEQKTDEE 364
Cdd:NF033838 351 KEAELELVKEEAKEPRNEE-------KIKQAKAKVESKKAEAT-RLEKIKTDRKKAEE 400
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
158-443 |
1.86e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 42.65 E-value: 1.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 158 AKLEKEEAERYQSLLEELKMNKIQLQLFQLYHNE----KKIHLLNTKLEHVNRDLSVKRESLSHHENIVKARKKEHGMLT 233
Cdd:TIGR00618 400 KELDILQREQATIDTRTSAFRDLQGQLAHAKKQQelqqRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKE 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 234 RQLQQTEKELKSVETLLNQKRPQYIKAKENTSHHLKKLDVAKKSIKDSeKQCSKQEDDIKALETELADLDAAWRSFEKQI 313
Cdd:TIGR00618 480 QIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLT-RRMQRGEQTYAQLETSEEDVYHQLTSERKQR 558
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 314 ---EEEILHKKRDIELEASQLDRYKELKEQVRKkvatMTQQLEKLQWEQKTDEERLAFEKRRHgEVQGNLKQIKEQIEDH 390
Cdd:TIGR00618 559 aslKEQMQEIQQSFSILTQCDNRSKEDIPNLQN----ITVRLQDLTEKLSEAEDMLACEQHAL-LRKLQPEQDLQDVRLH 633
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 768024649 391 KKRIEKLEEYTKTcmdclkEKKQQEETLVDEIEKTKSRMSEVNEELNLIRSEL 443
Cdd:TIGR00618 634 LQQCSQELALKLT------ALHALQLTLTQERVREHALSIRVLPKELLASRQL 680
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
169-436 |
2.36e-03 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 41.94 E-value: 2.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 169 QSLLEELKMNKIQLQLFQLYHNEKKIHLLNTKLEHVNRDLSVKRESLSHHeniVKARKKEHGMLTRQLQQTEKELKSVET 248
Cdd:pfam05667 206 PSLLERNAAELAAAQEWEEEWNSQGLASRLTPEEYRKRKRTKLLKRIAEQ---LRSAALAGTEATSGASRSAQDLAELLS 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 249 LLNQKRP-QYIKAKENTSHHLKKLDVAK---------KSIKDSEKQC-SKQEDDIKALETELADLDA----------AWR 307
Cdd:pfam05667 283 SFSGSSTtDTGLTKGSRFTHTEKLQFTNeapaatsspPTKVETEEELqQQREEELEELQEQLEDLESsiqelekeikKLE 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 308 SFEKQIEEEIlhkkRDIELEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAfekrrhgevqgnlkQIKEQI 387
Cdd:pfam05667 363 SSIKQVEEEL----EELKEQNEELEKQYKVKKKTLDLLPDAEENIAKLQALVDASAQRLV--------------ELAGQW 424
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 768024649 388 EDHKKR-IEKLEEYTKTCMDCLKEKKQQeetlVDEIEKTKSRMSEVNEEL 436
Cdd:pfam05667 425 EKHRVPlIEEYRALKEAKSNKEDESQRK----LEEIKELREKIKEVAEEA 470
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
210-465 |
2.41e-03 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 42.37 E-value: 2.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 210 VKRESLSHHENIVKARKKEHGMLTRQLQQTEKEL---KSVETLLN--QKRPQYiKAKENTSHHLKKLDVAKKSIkdseKQ 284
Cdd:COG5022 760 LRRRYLQALKRIKKIQVIQHGFRLRRLVDYELKWrlfIKLQPLLSllGSRKEY-RSYLACIIKLQKTIKREKKL----RE 834
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 285 CSKQEDDIKALETeladLDAAWRSFEKQIEEEILHKKRDIELEASQLD----RYKELKEQVrKKVATMTQQLEKLQWE-- 358
Cdd:COG5022 835 TEEVEFSLKAEVL----IQKFGRSLKAKKRFSLLKKETIYLQSAQRVElaerQLQELKIDV-KSISSLKLVNLELESEii 909
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 359 -----QKTDE-ERLAFEKRRHGEVQGNLK--QIKEQIEDHKKRIEKLEEYTKTCMDcLKEKKQQEETLVDEIEKTKSRMS 430
Cdd:COG5022 910 elkksLSSDLiENLEFKTELIARLKKLLNniDLEEGPSIEYVKLPELNKLHEVESK-LKETSEEYEDLLKKSTILVREGN 988
|
250 260 270
....*....|....*....|....*....|....*
gi 768024649 431 EVNEELNLIRSELQNAGIDTHEGKRQQKRAEVLEH 465
Cdd:COG5022 989 KANSELKNFKKELAELSKQYGALQESTKQLKELPV 1023
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
269-468 |
3.30e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.29 E-value: 3.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 269 KKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIeeeilhkkRDIELEASQLdrykelkeqvRKKVATM 348
Cdd:COG4942 27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRI--------RALEQELAAL----------EAELAEL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 349 TQQLEKLQWEQKTDEERLA------FEKRRHGEVQGNLKQikEQIEDHKKRIEKLEEYT---KTCMDCLKEKKQQEETLV 419
Cdd:COG4942 89 EKEIAELRAELEAQKEELAellralYRLGRQPPLALLLSP--EDFLDAVRRLQYLKYLAparREQAEELRADLAELAALR 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 768024649 420 DEIEKTKSRMSEVNEELNLIRSELQNAgidthegkrQQKRAEVLEHLKR 468
Cdd:COG4942 167 AELEAERAELEALLAELEEERAALEAL---------KAERQKLLARLEK 206
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
274-436 |
3.38e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 41.45 E-value: 3.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 274 AKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEeiLHKKRDIELEASQLDRYKelkeQVRKKVATMTQQLE 353
Cdd:PRK05771 84 LEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIER--LEPWGNFDLDLSLLLGFK----YVSVFVGTVPEDKL 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 354 KLQwEQKTDEERLAFEKRRHGEVQGNLKQIKEQIEDHKKRIEKLE------EYTKTCMDCLKEKKQQEETLVDEIEKTKS 427
Cdd:PRK05771 158 EEL-KLESDVENVEYISTDKGYVYVVVVVLKELSDEVEEELKKLGferlelEEEGTPSELIREIKEELEEIEKERESLLE 236
|
....*....
gi 768024649 428 RMSEVNEEL 436
Cdd:PRK05771 237 ELKELAKKY 245
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
628-882 |
3.74e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 41.70 E-value: 3.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 628 KELKNLRDRRSQKIQELKGLMKTLRKETDLKQIQ-TLIQGTQTRLK---YSQNELEMIKKKhlvaFYQEQSQLQSELLNI 703
Cdd:pfam01576 152 KERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHeAMISDLEERLKkeeKGRQELEKAKRK----LEGESTDLQEQIAEL 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 704 ESQcimLSEGIKERQRRIKEFQEKIDKVEDDIFQhfcEEIGVENIREFENKHVKRQQEIDQKRL---EFEKQKTRLNVQL 780
Cdd:pfam01576 228 QAQ---IAELRAQLAKKEEELQAALARLEEETAQ---KNNALKKIRELEAQISELQEDLESERAarnKAEKQRRDLGEEL 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 781 EYSRSHLKKKLNKINTLKETIQKGSEDIDHLKKAEEnclqtvNELMAKQQQLKDIRVTQNSSAEKVQTQIEEER------ 854
Cdd:pfam01576 302 EALKTELEDTLDTTAAQQELRSKREQEVTELKKALE------EETRSHEAQLQEMRQKHTQALEELTEQLEQAKrnkanl 375
|
250 260 270
....*....|....*....|....*....|..
gi 768024649 855 -KKFLAVDREVGKLQKEVVSIQTS---LEQKR 882
Cdd:pfam01576 376 eKAKQALESENAELQAELRTLQQAkqdSEHKR 407
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
119-852 |
3.82e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.57 E-value: 3.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 119 TSGELIGEYEEKKRKLQKAEEDAQfnfNKKKNIAAERRQAKLEKEEAERYQSLLEELKMnkiqlQLFQLYHNEKKIHLLN 198
Cdd:TIGR00606 197 TQGQKVQEHQMELKYLKQYKEKAC---EIRDQITSKEAQLESSREIVKSYENELDPLKN-----RLKEIEHNLSKIMKLD 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 199 TKL----------EHVNRDLSVKRESL------------SHHENIVKARKKEHGMLTRQLQQTEKELKsvetLLNQKRPQ 256
Cdd:TIGR00606 269 NEIkalksrkkqmEKDNSELELKMEKVfqgtdeqlndlyHNHQRTVREKERELVDCQRELEKLNKERR----LLNQEKTE 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 257 YIkaKENTSHHLKKLDVAKKSIK-DSEKQCSKQEDDIKALETElADLDAAWRSFEKQIEEEILHKKRDIELEASQLDRYK 335
Cdd:TIGR00606 345 LL--VEQGRLQLQADRHQEHIRArDSLIQSLATRLELDGFERG-PFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKE 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 336 ELKEQ------VRKKVATMTQQLEKLQWEQKTDEerLAFEKRRHGEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCM-DCL 408
Cdd:TIGR00606 422 RLKQEqadeirDEKKGLGRTIELKKEILEKKQEE--LKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLtETL 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 409 KEKKQQEETLVDEIEKTKSRMSEVNEELNLIRSELQNAGIDThegKRQQKRAEVLEHLKRLYPDSVFGRLFDLchpihkK 488
Cdd:TIGR00606 500 KKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLT---KDKMDKDEQIRKIKSRHSDELTSLLGYF------P 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 489 YQLAVTKVFGRFITAIVVASEKVAKDCIRFLKEERAEPETFLALDYLD--IKPINERLRELKGCKMV---IDVIKTQFPQ 563
Cdd:TIGR00606 571 NKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEeqLSSYEDKLFDVCGSQDEesdLERLKEEIEK 650
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 564 LKKVIQFVCGnglvcETMEEARHIALSGPERQKTVALDGTLFLKSGVISGGSSDLKYKARCWD------EKELKNLRDRR 637
Cdd:TIGR00606 651 SSKQRAMLAG-----ATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPdklkstESELKKKEKRR 725
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 638 SQKIQELKGLMKTL-RKETDLKQIQTLIQGTQTRLKYSQNELEmikkkhlvafyQEQSQLQSELLNIESQCIMLSE-GIK 715
Cdd:TIGR00606 726 DEMLGLAPGRQSIIdLKEKEIPELRNKLQKVNRDIQRLKNDIE-----------EQETLLGTIMPEEESAKVCLTDvTIM 794
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 716 ERqrrikeFQEKIDKVEDDIFQHFCEEIGVENIREFEnkHVKRQQEIDQKRLEFEKQKTRLNVQLEYSRS----HLKKKL 791
Cdd:TIGR00606 795 ER------FQMELKDVERKIAQQAAKLQGSDLDRTVQ--QVNQEKQEKQHELDTVVSKIELNRKLIQDQQeqiqHLKSKT 866
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 768024649 792 NKINTLKETIQKGSEDIDHLKKAEENCLQTVNELMAKQQQLKDIRVTQNSSAEKVQTQIEE 852
Cdd:TIGR00606 867 NELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEE 927
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
108-437 |
3.82e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 41.59 E-value: 3.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 108 KERTQFFEEISTSGELIGEYEEKKRKLQKAEEdaqfnfnKKKNIaaERRQAKLEK--EEAERYQSLLEELKMNKIQLQLF 185
Cdd:PRK03918 314 KRLSRLEEEINGIEERIKELEEKEERLEELKK-------KLKEL--EKRLEELEErhELYEEAKAKKEELERLKKRLTGL 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 186 QLYHNEKKIHLLNTKLEHVNRDLSVKRESLSHHENIVKARKKEHGMLT----------RQL-QQTEKELKSVETLLNQKR 254
Cdd:PRK03918 385 TPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcgRELtEEHRKELLEEYTAELKRI 464
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 255 PQYIKAKENTSHHLKKLDVAKKSIKDSEKQCSKQE---DDIKALETELA-----DLDAAWRSFEKqIEEEILHKKRDIEL 326
Cdd:PRK03918 465 EKELKEIEEKERKLRKELRELEKVLKKESELIKLKelaEQLKELEEKLKkynleELEKKAEEYEK-LKEKLIKLKGEIKS 543
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 327 EASQLDRYKELKEQvRKKVATMTQQLEKLQWEQKTDEERLAFEKRRhgEVQGNLKQIKE------QIEDHKKRIEKLEEY 400
Cdd:PRK03918 544 LKKELEKLEELKKK-LAELEKKLDELEEELAELLKELEELGFESVE--ELEERLKELEPfyneylELKDAEKELEREEKE 620
|
330 340 350
....*....|....*....|....*....|....*..
gi 768024649 401 TKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEELN 437
Cdd:PRK03918 621 LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS 657
|
|
| ABC_SMC5_euk |
cd03277 |
ATP-binding cassette domain of eukaryotic SMC5 proteins; The structural maintenance of ... |
1084-1141 |
4.42e-03 |
|
ATP-binding cassette domain of eukaryotic SMC5 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213244 [Multi-domain] Cd Length: 213 Bit Score: 39.89 E-value: 4.42e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 768024649 1084 SGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVssyikeqtqdqFQMIV 1141
Cdd:cd03277 128 SGGERSVSTMLYLLSLQELTRCPFRVVDEINQGMDPTNERKV-----------FDMLV 174
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
100-468 |
4.59e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 41.28 E-value: 4.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 100 ESISVKKPKERTQFFEEISTSGELIGEYEEKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERYQSLLEELKMNK 179
Cdd:PTZ00121 1086 DNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARK 1165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 180 IQLQlfQLYHNEKKIHLLNtKLEHVNRDLSVKR-------ESLSHHENIVK---------ARKKEHGMLTRQLQQTEKEL 243
Cdd:PTZ00121 1166 AEEA--RKAEDAKKAEAAR-KAEEVRKAEELRKaedarkaEAARKAEEERKaeearkaedAKKAEAVKKAEEAKKDAEEA 1242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 244 KSVETLLNQ---------------KRPQYIKAKE-NTSHHLKKLDVAKKS--IKDSEKQCSKQEDDIKALETELADlDAA 305
Cdd:PTZ00121 1243 KKAEEERNNeeirkfeearmahfaRRQAAIKAEEaRKADELKKAEEKKKAdeAKKAEEKKKADEAKKKAEEAKKAD-EAK 1321
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 306 WRSFEKQIEEEILHKKRDielEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQGNLKQIKE 385
Cdd:PTZ00121 1322 KKAEEAKKKADAAKKKAE---EAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKK 1398
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 386 QIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEELNLIRSELQNAgidtHEGKRQQKRAEVLEH 465
Cdd:PTZ00121 1399 KAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKA----EEAKKKAEEAKKADE 1474
|
...
gi 768024649 466 LKR 468
Cdd:PTZ00121 1475 AKK 1477
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
172-842 |
4.65e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 41.26 E-value: 4.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 172 LEELK---MNKIQLQLFQlyhNEKKIHLLNTKLEHVNRDLSVKRESLSHHENIVKAR--------KKEHGMLTRQLQQTE 240
Cdd:pfam15921 247 LEALKsesQNKIELLLQQ---HQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQleiiqeqaRNQNSMYMRQLSDLE 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 241 KELKSVETLLNQKRPQYIKAKENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIK-ALETELADLDAawRSFEKQIEEE--- 316
Cdd:pfam15921 324 STVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDdQLQKLLADLHK--REKELSLEKEqnk 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 317 ------------ILHKKRDIELEASQLDRYKELKEQVRKKV-ATMTQQLEKLQWEQKTDEERLAFEKRRHgEVQGNLKQI 383
Cdd:pfam15921 402 rlwdrdtgnsitIDHLRRELDDRNMEVQRLEALLKAMKSECqGQMERQMAAIQGKNESLEKVSSLTAQLE-STKEMLRKV 480
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 384 KEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEELNLIRSE---LQNAGIDTHEGKRQQ-KR 459
Cdd:pfam15921 481 VEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEgdhLRNVQTECEALKLQMaEK 560
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 460 AEVLEHLKRlypdsvfgrlfdlchPIHKKYQLAVTKvfGRFITAIVVasekvakdcirflkeERAEPEtflaldyldiKP 539
Cdd:pfam15921 561 DKVIEILRQ---------------QIENMTQLVGQH--GRTAGAMQV---------------EKAQLE----------KE 598
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 540 INERLRELKGCKMVIDVIKTQFPQLKkviqfvcgnGLVCETMEEARHIALSGPERQKTValdgtlflksgvisggsSDLK 619
Cdd:pfam15921 599 INDRRLELQEFKILKDKKDAKIRELE---------ARVSDLELEKVKLVNAGSERLRAV-----------------KDIK 652
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 620 yKARCWDEKELKNLRDRRSQKIQELKGLMKTLRKETDlkQIQTLIQGTQTRLKYSQNELEmikkkhlvafyQEQSQLQSe 699
Cdd:pfam15921 653 -QERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSE--EMETTTNKLKMQLKSAQSELE-----------QTRNTLKS- 717
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 700 LLNIESQCIMLSEGIkerQRRIKEFQEKIDKVEDDIfqHFCEEIGVENIREfenKHVKRQQ--EIDQKRLEFEKQKTRLN 777
Cdd:pfam15921 718 MEGSDGHAMKVAMGM---QKQITAKRGQIDALQSKI--QFLEEAMTNANKE---KHFLKEEknKLSQELSTVATEKNKMA 789
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768024649 778 VQLEYSRSHLKKKLNKINTLKETIQKGS----EDIDHLKKAEENCLQTVNELMAKQQQLKDIRVTQNSS 842
Cdd:pfam15921 790 GELEVLRSQERRLKEKVANMEVALDKASlqfaECQDIIQRQEQESVRLKLQHTLDVKELQGPGYTSNSS 858
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
119-883 |
5.92e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.19 E-value: 5.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 119 TSGELIGEYEEKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERYQSLLEeLKMNKIQLQLFQlYHNEKKIHLLN 198
Cdd:TIGR00606 299 TDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQ-LQADRHQEHIRA-RDSLIQSLATR 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 199 TKLEHVNRDLSVKRESLSHHENIVKARKKEHGMLTR---QLQQTEKELKSVETLLNQKRPQYIKAKENTSHHLKKLDVAK 275
Cdd:TIGR00606 377 LELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQlcaDLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEEL 456
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 276 KSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEEILhKKRDIELEASQLDRYKELKEQVRK-----KVATMTQ 350
Cdd:TIGR00606 457 KFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETL-KKEVKSLQNEKADLDRKLRKLDQEmeqlnHHTTTRT 535
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 351 QLEKLQWEQKTDEERLAFEKRRHG-EVQGNLKQI--KEQIED--HKKRIEKleEYTKTCMDCLKEKKQQEETLVDEIEKT 425
Cdd:TIGR00606 536 QMEMLTKDKMDKDEQIRKIKSRHSdELTSLLGYFpnKKQLEDwlHSKSKEI--NQTRDRLAKLNKELASLEQNKNHINNE 613
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 426 KSRMSEvnEELNLIRSELQNAGIDTHEGKRQQKRAEVLEHLKRLYPDSvfgrlfdlchpihkkyqlAVTKVFGRFITAIV 505
Cdd:TIGR00606 614 LESKEE--QLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRAMLA------------------GATAVYSQFITQLT 673
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 506 VASEKVAKDCIRFLKEERA--------EPETFLALDYLDI---------KPINERLRELKGCKMVIDVIKTQFPQLKKVI 568
Cdd:TIGR00606 674 DENQSCCPVCQRVFQTEAElqefisdlQSKLRLAPDKLKSteselkkkeKRRDEMLGLAPGRQSIIDLKEKEIPELRNKL 753
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 569 QFVcgnglvcetmeeARHIALSGPERQKTVALDGTLFLKSGVISGGSSDLKYKARCwdEKELKNLRDRRSQKIQELKGLM 648
Cdd:TIGR00606 754 QKV------------NRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERF--QMELKDVERKIAQQAAKLQGSD 819
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 649 KTLrketDLKQIQTLIQGTQTRLKYSQNELEMIKKkhLVAFYQEQSQ-LQSELLNIESQCIMLSEGIKERQRRIKEFQEK 727
Cdd:TIGR00606 820 LDR----TVQQVNQEKQEKQHELDTVVSKIELNRK--LIQDQQEQIQhLKSKTNELKSEKLQIGTNLQRRQQFEEQLVEL 893
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 728 IDKVEDDIFQHFCEEIGVENIREFENKHVKRQQEIDQKRlEFEKQKTRLNVQLeysrshLKKKL-NKINTLKETIQKGSE 806
Cdd:TIGR00606 894 STEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSK-ETSNKKAQDKVND------IKEKVkNIHGYMKDIENKIQD 966
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 807 DIDHLKKAEENCLQTVNELMAKQQQLK-----DIRVTQNS-SAEKVQTQIEEERKKFLAVDREVGKLQKEVVSIQTSLEQ 880
Cdd:TIGR00606 967 GKDDYLKQKETELNTVNAQLEECEKHQekineDMRLMRQDiDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQ 1046
|
...
gi 768024649 881 KRL 883
Cdd:TIGR00606 1047 MQV 1049
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
186-889 |
6.25e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 40.86 E-value: 6.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 186 QLYHNEKKIHLLNTKLEhvnRDLSVKRESLSHHENIVKARKKEHGMLtrQLQQTEKELKSVETLlnQKRPQYIKAKENTS 265
Cdd:pfam05483 82 KLYKEAEKIKKWKVSIE---AELKQKENKLQENRKIIEAQRKAIQEL--QFENEKVSLKLEEEI--QENKDLIKENNATR 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 266 HHLKKLdvakksikdsEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEEIL-HKKRDIELEASQLDRYKELKEQvRKK 344
Cdd:pfam05483 155 HLCNLL----------KETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMILaFEELRVQAENARLEMHFKLKED-HEK 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 345 VATMTQQLEKlqwEQKTDEERLAFEKRRHGEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEK 424
Cdd:pfam05483 224 IQHLEEEYKK---EINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELED 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 425 TKSRMSEVNEELNLIRSELQNAGIDTHEgKRQQKRAEVLEHLKrlypdsvfgrlfdlchpihkkyqlavTKVFGRFITAI 504
Cdd:pfam05483 301 IKMSLQRSMSTQKALEEDLQIATKTICQ-LTEEKEAQMEELNK--------------------------AKAAHSFVVTE 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 505 VVASEKVAKDCIRFLKEERAEPETFLALDYLDIKPINERLRELkgckmvidvikTQFPQLKKViqfvcgnglvceTMEEA 584
Cdd:pfam05483 354 FEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEM-----------TKFKNNKEV------------ELEEL 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 585 RhialsgperqKTVALDGTLFlksgvisggssdlkykarcWDEKELKNLRDRRSQKIQELKGLMKTLRKETDLKQIQtlI 664
Cdd:pfam05483 411 K----------KILAEDEKLL-------------------DEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQ--L 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 665 QGTQTRLKYSQNELEMIKkkhlvafyqeqSQLQSE-LLNIE--SQCIMLSEGIKERQRRIKEFQEKIDKVEDDIFQH-FC 740
Cdd:pfam05483 460 TAIKTSEEHYLKEVEDLK-----------TELEKEkLKNIEltAHCDKLLLENKELTQEASDMTLELKKHQEDIINCkKQ 528
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 741 EEIGVENIREFENKHVKRQQEIDQKRLEFEKQKTRLNVQLEYSRSHLKKKLNKINTLKETIQKGSEDIDHLKKAEENCLQ 820
Cdd:pfam05483 529 EERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNK 608
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 768024649 821 TVNELMAKQQQLKdirvtQNSSAEKVQTQIEEERKKFLAVDREVGKLQKEVV--SIQTSLEQKRLEKHNLL 889
Cdd:pfam05483 609 NIEELHQENKALK-----KKGSAENKQLNAYEIKVNKLELELASAKQKFEEIidNYQKEIEDKKISEEKLL 674
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
108-356 |
6.42e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 40.77 E-value: 6.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 108 KERTQFFEEistsgeligEYEEKKRKLQKAEEDAQfNFNKKKNIAAERRQAKLEKEEAERYQSLLEELKMNKIQLQlfql 187
Cdd:COG3206 174 RKALEFLEE---------QLPELRKELEEAEAALE-EFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAE---- 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 188 yhnekkihllnTKLEHVNRDLSVKRESLSHHENIVKARKkehgmLTRQLQQTEKELKSVETLLNQKRPQYIKAKEntshh 267
Cdd:COG3206 240 -----------ARLAALRAQLGSGPDALPELLQSPVIQQ-----LRAQLAELEAELAELSARYTPNHPDVIALRA----- 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 268 lkKLDVAKKSIKDSEKQcskqedDIKALETELADLDAAWRSFEKQIEEEilhkKRDIELEASQLDRYKELKEQVRKKVAT 347
Cdd:COG3206 299 --QIAALRAQLQQEAQR------ILASLEAELEALQAREASLQAQLAQL----EARLAELPELEAELRRLEREVEVAREL 366
|
....*....
gi 768024649 348 MTQQLEKLQ 356
Cdd:COG3206 367 YESLLQRLE 375
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
140-367 |
6.49e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.20 E-value: 6.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 140 DAQFNFNKKKNIAAERRQAKLEKEeaerYQSLLEELkmNKIQLQLFQLyhnEKKIHLLNTKLEHVNRDLSVKRESLSHHE 219
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAE----LDALQAEL--EELNEEYNEL---QAELEALQAEIDKLQAEIAEAEAEIEERR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 220 NIVKARkkehgmlTRQLQQTEKELKSVETLLNQkrpqyikakENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETEL 299
Cdd:COG3883 86 EELGER-------ARALYRSGGSVSYLDVLLGS---------ESFSDFLDRLSALSKIADADADLLEELKADKAELEAKK 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 768024649 300 ADLDAAWRSFEKQIEEEILHKKrdiELEAsQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLA 367
Cdd:COG3883 150 AELEAKLAELEALKAELEAAKA---ELEA-QQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAA 213
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
128-316 |
6.59e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.13 E-value: 6.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 128 EEKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERYQSLLEElKMNKIQLQLFQLyhnEKKIHLLNTKLEHVNRD 207
Cdd:COG4942 23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALAR-RIRALEQELAAL---EAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 208 LSVKRESLSH--------------------------------HENIVKARKKehgmLTRQLQQTEKELKSVETLLNQKRP 255
Cdd:COG4942 99 LEAQKEELAEllralyrlgrqpplalllspedfldavrrlqyLKYLAPARRE----QAEELRADLAELAALRAELEAERA 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768024649 256 QYIKAKENTSHHLKKLDVAKKS----IKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEE 316
Cdd:COG4942 175 ELEALLAELEEERAALEALKAErqklLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
614-854 |
6.64e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 40.98 E-value: 6.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 614 GSSDLKYKARCwDEKELKNLRDRRSQKIQELKGLMKTLRKETDLKQIQTLI---------QGTQTRLKYSQNELEMIKKK 684
Cdd:pfam12128 284 TSAELNQLLRT-LDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAfldadietaAADQEQLPSWQSELENLEER 362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 685 H---LVAFYQEQSQLQSELLNIESQCIMLSEGIKERQRRIKEFQEKIDKVEDDIFQHFCEEIgvenirefenkhvkrQQE 761
Cdd:pfam12128 363 LkalTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESEL---------------REQ 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 762 IDQKRLEFEKQKTRLNVQLEysrsHLKKKLNKINT---LKETIQKGSEDIDHLKKAEENCLQTVNELMAKQQQLKDIRVT 838
Cdd:pfam12128 428 LEAGKLEFNEEEYRLKSRLG----ELKLRLNQATAtpeLLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQ 503
|
250
....*....|....*.
gi 768024649 839 QNSSAEKVQTQIEEER 854
Cdd:pfam12128 504 ASEALRQASRRLEERQ 519
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
331-469 |
6.65e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 40.61 E-value: 6.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 331 LDRYKELKEQVRKKV----------------ATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQGNLKQikEQIEDHKKRI 394
Cdd:COG2433 345 YDAYKNKFERVEKKVppdvdrdevkarvirgLSIEEALEELIEKELPEEEPEAEREKEHEERELTEEE--EEIRRLEEQV 422
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768024649 395 EKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSE---VNEELNLIRSELQNAgidTHEGKRQQKRAEVLE-HLKRL 469
Cdd:COG2433 423 ERLEAEVEELEAELEEKDERIERLERELSEARSEERReirKDREISRLDREIERL---ERELEEERERIEELKrKLERL 498
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
256-445 |
7.11e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 40.38 E-value: 7.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 256 QYIKAKENTSHHLK-KLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEEILHKKRDIELEASQLDRy 334
Cdd:PHA02562 181 QQIQTLDMKIDHIQqQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNK- 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 335 kelkeqVRKKVATMTQQLEKLQWEQKTDEErlafekrrHGEVqgnlKQIKEQIEDHKKRIEKLEEYTKTC---MDCLKEK 411
Cdd:PHA02562 260 ------LNTAAAKIKSKIEQFQKVIKMYEK--------GGVC----PTCTQQISEGPDRITKIKDKLKELqhsLEKLDTA 321
|
170 180 190
....*....|....*....|....*....|....
gi 768024649 412 KQQEETLVDEIEKTKSRMSEVNEELNLIRSELQN 445
Cdd:PHA02562 322 IDELEEIMDEFNEQSKKLLELKNKISTNKQSLIT 355
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
129-433 |
7.40e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 40.81 E-value: 7.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 129 EKKRKLQKAEEDAQFNFNKKKNiaaerrqakleKEEAERYQSLLEELKMNKIQLQLFQLYHNEKKIHLLNTKLEHVNRDL 208
Cdd:TIGR01612 974 DKINELDKAFKDASLNDYEAKN-----------NELIKYFNDLKANLGKNKENMLYHQFDEKEKATNDIEQKIEDANKNI 1042
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 209 SvkRESLSHHENIVKARKKEHGMLTRQLQQTEKE-LKSVETLLNQ--KRPQYIK-------AKENTSHHLKKLDVAKKSI 278
Cdd:TIGR01612 1043 P--NIEIAIHTSIYNIIDEIEKEIGKNIELLNKEiLEEAEINITNfnEIKEKLKhynfddfGKEENIKYADEINKIKDDI 1120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 279 KDSEKQC-----------SKQEDDIKALETELADL-DAAWRSFEKQIEEEILHKKRDIeleASQLDRYKELKEQVrKKVA 346
Cdd:TIGR01612 1121 KNLDQKIdhhikaleeikKKSENYIDEIKAQINDLeDVADKAISNDDPEEIEKKIENI---VTKIDKKKNIYDEI-KKLL 1196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 347 TMTQQLEKlqweQKTDEERLAFEKRRHGEVQGNLkqIKEQIEDHKKR----IEKLEEYTKTcMDCLKEKKQQEETLVDEI 422
Cdd:TIGR01612 1197 NEIAEIEK----DKTSLEEVKGINLSYGKNLGKL--FLEKIDEEKKKsehmIKAMEAYIED-LDEIKEKSPEIENEMGIE 1269
|
330
....*....|.
gi 768024649 423 EKTKSRMSEVN 433
Cdd:TIGR01612 1270 MDIKAEMETFN 1280
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
191-400 |
7.56e-03 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 40.49 E-value: 7.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 191 EKKIHLLNTKLEHV---NRDLSVKRESLSHHENIVKARKKEHGMLTRQLQqteKELKSVETLLNQKRPQYIKAKENTSHH 267
Cdd:pfam05557 33 EKKASALKRQLDREsdrNQELQKRIRLLEKREAEAEEALREQAELNRLKK---KYLEALNKKLNEKESQLADAREVISCL 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 268 LKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEeiLHKKRDIELEASQ----LDRYKELKEQVRK 343
Cdd:pfam05557 110 KNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQN--LEKQQSSLAEAEQrikeLEFEIQSQEQDSE 187
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 768024649 344 KVATMTQQLEKLQwEQKTDEERLAFEKRRHGEVQGNLKQIKEQIEDHKKRIEKLEEY 400
Cdd:pfam05557 188 IVKNSKSELARIP-ELEKELERLREHNKHLNENIENKLLLKEEVEDLKRKLEREEKY 243
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
779-1007 |
8.20e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.20 E-value: 8.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 779 QLEYSRSHLKKKLNKINTLKETIQKGSEDIDhlkKAEENCLQTVNELMAKQQQLKDIrvtqNSSAEKVQTQIEEERKkfl 858
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELE---ELNEEYNELQAELEALQAEIDKL----QAEIAEAEAEIEERRE--- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 859 avdrevgKLQKEVVSIQTSLEQkrlekhnllldckVQDIEIILLSGSLDDIIE--VEMGTEAESTQATIDiyekeeafei 936
Cdd:COG3883 87 -------ELGERARALYRSGGS-------------VSYLDVLLGSESFSDFLDrlSALSKIADADADLLE---------- 136
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 768024649 937 DYSSLKEDLKALQSD-QEIEAHLRLLLQQVASQEDILLKTAAPNLRALENLKTVRDKFQESTDAFEASRKEA 1007
Cdd:COG3883 137 ELKADKAELEAKKAElEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAA 208
|
|
| cdk7 |
TIGR00570 |
CDK-activating kinase assembly factor MAT1; All proteins in this family for which functions ... |
269-435 |
9.35e-03 |
|
CDK-activating kinase assembly factor MAT1; All proteins in this family for which functions are known are cyclin dependent protein kinases that are components of TFIIH, a complex that is involved in nucleotide excision repair and transcription initiation. Also known as MAT1 (menage a trois 1). This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129661 [Multi-domain] Cd Length: 309 Bit Score: 39.79 E-value: 9.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 269 KKLDVAKKSIKDSekqcSKQEDDIKALeteladldAAWRSFEKQIEEEILHKKRDIELEASQ--LDRYKELKEQVRKKva 346
Cdd:TIGR00570 70 KEVDIRKRVLKIY----NKREEDFPSL--------REYNDYLEEVEDIVYNLTNNIDLENTKkkIETYQKENKDVIQK-- 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024649 347 tmtqQLEKLQWEQKTDEERLAFEkrrhgevqgnlkqiKEQIEDHKKRIEKLEEYTKtcmdclKEKKQQEETLVDEIEKTK 426
Cdd:TIGR00570 136 ----NKEKSTREQEELEEALEFE--------------KEEEEQRRLLLQKEEEEQQ------MNKRKNKQALLDELETST 191
|
....*....
gi 768024649 427 SRMSEVNEE 435
Cdd:TIGR00570 192 LPAAELIAQ 200
|
|
| |
