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Conserved domains on  [gi|768017959|ref|XP_011527279|]
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syndecan-4 isoform X1 [Homo sapiens]

Protein Classification

syndecan( domain architecture ID 10470665)

syndecan is a cell surface proteoglycan that may bear both heparan sulfate and chondroitin sulfate and may link the cytoskeleton to the interstitial matrix

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Syndecan pfam01034
Syndecan domain; Syndecans are transmembrane heparin sulfate proteoglycans which are ...
67-125 9.34e-28

Syndecan domain; Syndecans are transmembrane heparin sulfate proteoglycans which are implicated in the binding of extracellular matrix components and growth factors.


:

Pssm-ID: 460035  Cd Length: 63  Bit Score: 96.69  E-value: 9.34e-28
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 768017959   67 NIFERTEVLAALIVGGIVGILFAVFLILLLMYRMKKKDEGSYDLGKKPI----YKKAPTNEFY 125
Cdd:pfam01034   1 SIFERPEVLAAVIGGGVVGLLFAVLLVMFLVYRMKKKDEGSYALDEPKQannyYTKAPTKEEF 63
 
Name Accession Description Interval E-value
Syndecan pfam01034
Syndecan domain; Syndecans are transmembrane heparin sulfate proteoglycans which are ...
67-125 9.34e-28

Syndecan domain; Syndecans are transmembrane heparin sulfate proteoglycans which are implicated in the binding of extracellular matrix components and growth factors.


Pssm-ID: 460035  Cd Length: 63  Bit Score: 96.69  E-value: 9.34e-28
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 768017959   67 NIFERTEVLAALIVGGIVGILFAVFLILLLMYRMKKKDEGSYDLGKKPI----YKKAPTNEFY 125
Cdd:pfam01034   1 SIFERPEVLAAVIGGGVVGLLFAVLLVMFLVYRMKKKDEGSYALDEPKQannyYTKAPTKEEF 63
4.1m smart00294
putative band 4.1 homologues' binding motif;
97-115 1.21e-05

putative band 4.1 homologues' binding motif;


Pssm-ID: 128590  Cd Length: 19  Bit Score: 39.43  E-value: 1.21e-05
                           10
                   ....*....|....*....
gi 768017959    97 MYRMKKKDEGSYDLGKKPI 115
Cdd:smart00294   1 MYRYKHRDEGSYHTHEPKG 19
 
Name Accession Description Interval E-value
Syndecan pfam01034
Syndecan domain; Syndecans are transmembrane heparin sulfate proteoglycans which are ...
67-125 9.34e-28

Syndecan domain; Syndecans are transmembrane heparin sulfate proteoglycans which are implicated in the binding of extracellular matrix components and growth factors.


Pssm-ID: 460035  Cd Length: 63  Bit Score: 96.69  E-value: 9.34e-28
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 768017959   67 NIFERTEVLAALIVGGIVGILFAVFLILLLMYRMKKKDEGSYDLGKKPI----YKKAPTNEFY 125
Cdd:pfam01034   1 SIFERPEVLAAVIGGGVVGLLFAVLLVMFLVYRMKKKDEGSYALDEPKQannyYTKAPTKEEF 63
4.1m smart00294
putative band 4.1 homologues' binding motif;
97-115 1.21e-05

putative band 4.1 homologues' binding motif;


Pssm-ID: 128590  Cd Length: 19  Bit Score: 39.43  E-value: 1.21e-05
                           10
                   ....*....|....*....
gi 768017959    97 MYRMKKKDEGSYDLGKKPI 115
Cdd:smart00294   1 MYRYKHRDEGSYHTHEPKG 19
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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