|
Name |
Accession |
Description |
Interval |
E-value |
| Nucleic_acid_bd |
pfam13820 |
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding ... |
48-195 |
2.40e-59 |
|
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding proteins. Several members are annotated as being nuclear receptor coactivator 6 proteins but this could not be confirmed.
:
Pssm-ID: 463988 Cd Length: 143 Bit Score: 200.73 E-value: 2.40e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 48 IFVAFKGNIDDkdFKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLRDLGILSV 127
Cdd:pfam13820 1 TFLAVKGNLRM--FQEKLDSIRENVAELLRTEKSKLKVRKVEPWNSVRVTFSIPREAALRLRLLAQHNDPRLRDLGILSV 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 768016694 128 QIEGEGAINLALA---QNRSQDVRMnGPMGAGNSVRMEAGFPMASGPGIFflgiiRMNNPATVMIPPGGNV 195
Cdd:pfam13820 79 QIEGEGPINLTLAtmvQNPADDIIL-GCSTQLNSQRAEQGWTMLSALGLI-----SDALPLHLRLAESGEY 143
|
|
| Med15 super family |
cl26621 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
518-832 |
3.71e-09 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
The actual alignment was detected with superfamily member pfam09606:
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 61.95 E-value: 3.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 518 ANPNFMQGQVPSTTATTPGNSGAPQLQANQNVqhAGGQGAGPPQNQMQVSHGPPnmmQPSLMGIHGNMNNQQAGTsGVPQ 597
Cdd:pfam09606 58 AQQQQPQGGQGNGGMGGGQQGMPDPINALQNL--AGQGTRPQMMGPMGPGPGGP---MGQQMGGPGTASNLLASL-GRPQ 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 598 VNL------SNMQGQPQQGPPSQLMGMHQQIVPSQGQ-MVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPS-PQ 669
Cdd:pfam09606 132 MPMggagfpSQMSRVGRMQPGGQAGGMMQPSSGQPGSgTPNQMGPNGGPGQGQAGGMNGGQQGPMGGQMPPQMGVPGmPG 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 670 RMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQgnm 749
Cdd:pfam09606 212 PADAGAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQQSQLGMGINQMQQMPQGVGGGAGQGGPGQPMGPPG--- 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 750 vQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPhmaQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQA 829
Cdd:pfam09606 289 -QQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQ---QQMNQSVGQGGQVVALGGLNHLETWNPGNFGGLGANP 364
|
...
gi 768016694 830 MQG 832
Cdd:pfam09606 365 MQR 367
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
1050-1296 |
3.06e-06 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.63 E-value: 3.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1050 PPRGPLNPDSQRMPmqQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEA 1129
Cdd:PHA03247 2744 VPAGPATPGGPARP--ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1130 SG---------SEAPSVPGGPNNMPSHVVLPQNQLMMTGP--KPGPSPLSATQGATPQQPPVNSLPSshghhfPNVAAPT 1198
Cdd:PHA03247 2822 ASpagplppptSAQPTAPPPPPGPPPPSLPLGGSVAPGGDvrRRPPSRSPAAKPAAPARPPVRRLAR------PAVSRST 2895
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1199 QTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLnasiaglfPPQINIPLPPRPNLNRGFDQQGLNPttlkaig 1278
Cdd:PHA03247 2896 ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP--------PPRPQPPLAPTTDPAGAGEPSGAVP------- 2960
|
250
....*....|....*...
gi 768016694 1279 qAPSNLTMNPSNFATPQT 1296
Cdd:PHA03247 2961 -QPWLGALVPGRVAVPRF 2977
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
190-497 |
2.37e-04 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.47 E-value: 2.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 190 PPGGNVSSSMMAPGPNPELQPRtPRPASQSDamdPLLSGLHIQQQSHPSGSLAP-----PHHPMQPVSVNRQMNPANFPQ 264
Cdd:PHA03247 2690 PTVGSLTSLADPPPPPPTPEPA-PHALVSAT---PLPPGPAAARQASPALPAAPappavPAGPATPGGPARPARPPTTAG 2765
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 265 LQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHqqqqpqgirPQFTAPTQVPVPPGWNQLPSGALQPPPaqgsLGTMT 344
Cdd:PHA03247 2766 PPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPS---------PWDPADPPAAVLAPAAALPPAASPAGP----LPPPT 2832
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 345 ANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSL-QGGPSRVPTPL 423
Cdd:PHA03247 2833 SAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALpPDQPERPPQPQ 2912
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768016694 424 QQPHLTNKSPASSPssfqqgsPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVP-PNFMVM 497
Cdd:PHA03247 2913 APPPPQPQPQPPPP-------PQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAvPRFRVP 2980
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Nucleic_acid_bd |
pfam13820 |
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding ... |
48-195 |
2.40e-59 |
|
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding proteins. Several members are annotated as being nuclear receptor coactivator 6 proteins but this could not be confirmed.
Pssm-ID: 463988 Cd Length: 143 Bit Score: 200.73 E-value: 2.40e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 48 IFVAFKGNIDDkdFKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLRDLGILSV 127
Cdd:pfam13820 1 TFLAVKGNLRM--FQEKLDSIRENVAELLRTEKSKLKVRKVEPWNSVRVTFSIPREAALRLRLLAQHNDPRLRDLGILSV 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 768016694 128 QIEGEGAINLALA---QNRSQDVRMnGPMGAGNSVRMEAGFPMASGPGIFflgiiRMNNPATVMIPPGGNV 195
Cdd:pfam13820 79 QIEGEGPINLTLAtmvQNPADDIIL-GCSTQLNSQRAEQGWTMLSALGLI-----SDALPLHLRLAESGEY 143
|
|
| Med15 |
pfam09606 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
518-832 |
3.71e-09 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 61.95 E-value: 3.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 518 ANPNFMQGQVPSTTATTPGNSGAPQLQANQNVqhAGGQGAGPPQNQMQVSHGPPnmmQPSLMGIHGNMNNQQAGTsGVPQ 597
Cdd:pfam09606 58 AQQQQPQGGQGNGGMGGGQQGMPDPINALQNL--AGQGTRPQMMGPMGPGPGGP---MGQQMGGPGTASNLLASL-GRPQ 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 598 VNL------SNMQGQPQQGPPSQLMGMHQQIVPSQGQ-MVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPS-PQ 669
Cdd:pfam09606 132 MPMggagfpSQMSRVGRMQPGGQAGGMMQPSSGQPGSgTPNQMGPNGGPGQGQAGGMNGGQQGPMGGQMPPQMGVPGmPG 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 670 RMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQgnm 749
Cdd:pfam09606 212 PADAGAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQQSQLGMGINQMQQMPQGVGGGAGQGGPGQPMGPPG--- 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 750 vQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPhmaQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQA 829
Cdd:pfam09606 289 -QQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQ---QQMNQSVGQGGQVVALGGLNHLETWNPGNFGGLGANP 364
|
...
gi 768016694 830 MQG 832
Cdd:pfam09606 365 MQR 367
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1050-1296 |
3.06e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.63 E-value: 3.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1050 PPRGPLNPDSQRMPmqQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEA 1129
Cdd:PHA03247 2744 VPAGPATPGGPARP--ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1130 SG---------SEAPSVPGGPNNMPSHVVLPQNQLMMTGP--KPGPSPLSATQGATPQQPPVNSLPSshghhfPNVAAPT 1198
Cdd:PHA03247 2822 ASpagplppptSAQPTAPPPPPGPPPPSLPLGGSVAPGGDvrRRPPSRSPAAKPAAPARPPVRRLAR------PAVSRST 2895
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1199 QTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLnasiaglfPPQINIPLPPRPNLNRGFDQQGLNPttlkaig 1278
Cdd:PHA03247 2896 ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP--------PPRPQPPLAPTTDPAGAGEPSGAVP------- 2960
|
250
....*....|....*...
gi 768016694 1279 qAPSNLTMNPSNFATPQT 1296
Cdd:PHA03247 2961 -QPWLGALVPGRVAVPRF 2977
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
606-749 |
6.43e-05 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 47.88 E-value: 6.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 606 QPQQGPPSQ-LMGMHQQIVPSQGQMVQQQGTLNPQNPMilsraqLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQ 684
Cdd:TIGR01628 384 QLPMGSPMGgAMGQPPYYGQGPQQQFNGQPLGWPRMSM------MPTPMGPGGPLRPNGLAPMNAVRAPSRNAQNAAQKP 457
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768016694 685 MMAPHNQMMGPQGQVLLQQNPmieqimtnqmqgnkQQFNTQNQSNVMPGPAQIMRGPTPNMQGNM 749
Cdd:TIGR01628 458 PMQPVMYPPNYQSLPLSQDLP--------------QPQSTASQGGQNKKLAQVLASATPQMQKQV 508
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
190-497 |
2.37e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.47 E-value: 2.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 190 PPGGNVSSSMMAPGPNPELQPRtPRPASQSDamdPLLSGLHIQQQSHPSGSLAP-----PHHPMQPVSVNRQMNPANFPQ 264
Cdd:PHA03247 2690 PTVGSLTSLADPPPPPPTPEPA-PHALVSAT---PLPPGPAAARQASPALPAAPappavPAGPATPGGPARPARPPTTAG 2765
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 265 LQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHqqqqpqgirPQFTAPTQVPVPPGWNQLPSGALQPPPaqgsLGTMT 344
Cdd:PHA03247 2766 PPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPS---------PWDPADPPAAVLAPAAALPPAASPAGP----LPPPT 2832
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 345 ANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSL-QGGPSRVPTPL 423
Cdd:PHA03247 2833 SAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALpPDQPERPPQPQ 2912
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768016694 424 QQPHLTNKSPASSPssfqqgsPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVP-PNFMVM 497
Cdd:PHA03247 2913 APPPPQPQPQPPPP-------PQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAvPRFRVP 2980
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1101-1396 |
1.06e-03 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 44.14 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1101 SNSRKMVYQESPQNPSSSPLAEmaslpeASGSEAPSVPGGpnnMPSHVVLPQNQLM--MTGPK------PGPSPLSATQG 1172
Cdd:pfam05109 414 TTTHKVIFSKAPESTTTSPTLN------TTGFAAPNTTTG---LPSSTHVPTNLTApaSTGPTvstadvTSPTPAGTTSG 484
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1173 ATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQ-TPNNRPPS---TEPSE--ISLSPERLNASIAGLF 1246
Cdd:pfam05109 485 ASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTpTPNATSPTlgkTSPTSavTTPTPNATSPTPAVTT 564
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1247 P-PQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRR 1325
Cdd:pfam05109 565 PtPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSM 644
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 768016694 1326 SSPGSSRKTTPSPGRQN---SKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGlnPQNST 1396
Cdd:pfam05109 645 SLRPSSISETLSPSTSDnstSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTSQASG--PGNSS 716
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
385-492 |
1.81e-03 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 43.49 E-value: 1.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 385 SQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQ----QGSPASSPTVNQTQQQMGP 460
Cdd:pfam09770 211 AQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTILQrpqsPQPDPAQPSIQPQAQQFHQ 290
|
90 100 110
....*....|....*....|....*....|....
gi 768016694 461 RPPQNNPLP-QGFQQP-VSSPGRNPMVQQGNVPP 492
Cdd:pfam09770 291 QPPPVPVQPtQILQNPnRLSAARVGYPQNPQPGV 324
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Nucleic_acid_bd |
pfam13820 |
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding ... |
48-195 |
2.40e-59 |
|
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding proteins. Several members are annotated as being nuclear receptor coactivator 6 proteins but this could not be confirmed.
Pssm-ID: 463988 Cd Length: 143 Bit Score: 200.73 E-value: 2.40e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 48 IFVAFKGNIDDkdFKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLRDLGILSV 127
Cdd:pfam13820 1 TFLAVKGNLRM--FQEKLDSIRENVAELLRTEKSKLKVRKVEPWNSVRVTFSIPREAALRLRLLAQHNDPRLRDLGILSV 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 768016694 128 QIEGEGAINLALA---QNRSQDVRMnGPMGAGNSVRMEAGFPMASGPGIFflgiiRMNNPATVMIPPGGNV 195
Cdd:pfam13820 79 QIEGEGPINLTLAtmvQNPADDIIL-GCSTQLNSQRAEQGWTMLSALGLI-----SDALPLHLRLAESGEY 143
|
|
| Med15 |
pfam09606 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
518-832 |
3.71e-09 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 61.95 E-value: 3.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 518 ANPNFMQGQVPSTTATTPGNSGAPQLQANQNVqhAGGQGAGPPQNQMQVSHGPPnmmQPSLMGIHGNMNNQQAGTsGVPQ 597
Cdd:pfam09606 58 AQQQQPQGGQGNGGMGGGQQGMPDPINALQNL--AGQGTRPQMMGPMGPGPGGP---MGQQMGGPGTASNLLASL-GRPQ 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 598 VNL------SNMQGQPQQGPPSQLMGMHQQIVPSQGQ-MVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPS-PQ 669
Cdd:pfam09606 132 MPMggagfpSQMSRVGRMQPGGQAGGMMQPSSGQPGSgTPNQMGPNGGPGQGQAGGMNGGQQGPMGGQMPPQMGVPGmPG 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 670 RMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQgnm 749
Cdd:pfam09606 212 PADAGAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQQSQLGMGINQMQQMPQGVGGGAGQGGPGQPMGPPG--- 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 750 vQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPhmaQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQA 829
Cdd:pfam09606 289 -QQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQ---QQMNQSVGQGGQVVALGGLNHLETWNPGNFGGLGANP 364
|
...
gi 768016694 830 MQG 832
Cdd:pfam09606 365 MQR 367
|
|
| Med15 |
pfam09606 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
277-742 |
2.15e-06 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 53.09 E-value: 2.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 277 QQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAptqvPVPPGwNQLPSGALQPPPAQGSLGTMTANQGWKK---AP 353
Cdd:pfam09606 64 QGGQGNGGMGGGQQGMPDPINALQNLAGQGTRPQMMG----PMGPG-PGGPMGQQMGGPGTASNLLASLGRPQMPmggAG 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 354 LPGPMQQQLQARPSLATvqtpsHPPPPYPFGSQQASQAHTNFPQMSnPGQFTAPQMKSLQGGPSRVPTPLQ--------- 424
Cdd:pfam09606 139 FPSQMSRVGRMQPGGQA-----GGMMQPSSGQPGSGTPNQMGPNGG-PGQGQAGGMNGGQQGPMGGQMPPQmgvpgmpgp 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 425 ---QPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMgpRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMvmqqQP 501
Cdd:pfam09606 213 adaGAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQ--QQGQQSQLGMGINQMQQMPQGVGGGAGQGGPGQPM----GP 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 502 PNQGPQSLHPGLGAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMqvshGPPNMMQPSLMGI 581
Cdd:pfam09606 287 PGQQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQQQMNQSVGQGGQVVALGGLNHL----ETWNPGNFGGLGA 362
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 582 HGnMNNQQAGTSGVPQVnlSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPS 661
Cdd:pfam09606 363 NP-MQRGQPGMMSSPSP--VPGQQVRQVTPNQFMRQSPQPSVPSPQGPGSQPPQSHPGGMIPSPALIPSPSPQMSQQPAQ 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 662 QNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQsnvMPGPAQIMRGP 741
Cdd:pfam09606 440 QRTIGQDSPGGSLNTPGQSAVNSPLNPQEEQLYREKYRQLTKYIEPLKRMIAKMENDPGDIDKMNK---MKRLLEILSNP 516
|
.
gi 768016694 742 T 742
Cdd:pfam09606 517 S 517
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1050-1296 |
3.06e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.63 E-value: 3.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1050 PPRGPLNPDSQRMPmqQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEA 1129
Cdd:PHA03247 2744 VPAGPATPGGPARP--ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1130 SG---------SEAPSVPGGPNNMPSHVVLPQNQLMMTGP--KPGPSPLSATQGATPQQPPVNSLPSshghhfPNVAAPT 1198
Cdd:PHA03247 2822 ASpagplppptSAQPTAPPPPPGPPPPSLPLGGSVAPGGDvrRRPPSRSPAAKPAAPARPPVRRLAR------PAVSRST 2895
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1199 QTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLnasiaglfPPQINIPLPPRPNLNRGFDQQGLNPttlkaig 1278
Cdd:PHA03247 2896 ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP--------PPRPQPPLAPTTDPAGAGEPSGAVP------- 2960
|
250
....*....|....*...
gi 768016694 1279 qAPSNLTMNPSNFATPQT 1296
Cdd:PHA03247 2961 -QPWLGALVPGRVAVPRF 2977
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
606-776 |
3.19e-06 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 52.35 E-value: 3.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 606 QPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQnpmilsraQLMPQGQMMVNPPSQNLGPSPQRmtppkqmLSQQGPQM 685
Cdd:pfam09770 209 KPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQ--------QQQPQQQPQQPQQHPGQGHPVTI-------LQRPQSPQ 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 686 MAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQsnvMPGPAQIMRGPTPNMQgnmvqftGQMSGQMLPQQG 765
Cdd:pfam09770 274 PDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVG---YPQNPQPGVQPAPAHQ-------AHRQQGSFGRQA 343
|
170
....*....|.
gi 768016694 766 PVNNSPSQVMG 776
Cdd:pfam09770 344 PIITHPQQLAQ 354
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1079-1553 |
3.44e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.17 E-value: 3.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1079 PASVPPSPDkQRMPMPVNTPlgsnsrkmvyqeSPQNPSSSPLAEMASLPEASGSeaPSVPGGPNNMPSHVV----LPQNQ 1154
Cdd:PHA03247 2557 PAAPPAAPD-RSVPPPRPAP------------RPSEPAVTSRARRPDAPPQSAR--PRAPVDDRGDPRGPAppspLPPDT 2621
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1155 LMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLS 1234
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADP 2701
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1235 PERLNASIAGLFPPQINIPLPPRPNLNRgfdqQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGA 1314
Cdd:PHA03247 2702 PPPPPTPEPAPHALVSATPLPPGPAAAR----QASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAA 2777
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1315 TKRASPSNSRRSSPGSSRKTTPS---PGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLN 1391
Cdd:PHA03247 2778 GPPRRLTRPAVASLSESRESLPSpwdPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVA 2857
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1392 PQNSTVSVAAVGGVVEDNKESLNVPQDSdcqnsqsrkeqvnIELKAVPAQEVKMVVPEDQSKKDGQPSDPNK--LPSVEE 1469
Cdd:PHA03247 2858 PGGDVRRRPPSRSPAAKPAAPARPPVRR-------------LARPAVSRSTESFALPPDQPERPPQPQAPPPpqPQPQPP 2924
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1470 NKNLVSPAMREAPTSLSQL---LDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHS 1546
Cdd:PHA03247 2925 PPPQPQPPPPPPPRPQPPLaptTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRV 3004
|
....*..
gi 768016694 1547 NELCSSL 1553
Cdd:PHA03247 3005 SSWASSL 3011
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
606-749 |
6.43e-05 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 47.88 E-value: 6.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 606 QPQQGPPSQ-LMGMHQQIVPSQGQMVQQQGTLNPQNPMilsraqLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQ 684
Cdd:TIGR01628 384 QLPMGSPMGgAMGQPPYYGQGPQQQFNGQPLGWPRMSM------MPTPMGPGGPLRPNGLAPMNAVRAPSRNAQNAAQKP 457
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768016694 685 MMAPHNQMMGPQGQVLLQQNPmieqimtnqmqgnkQQFNTQNQSNVMPGPAQIMRGPTPNMQGNM 749
Cdd:TIGR01628 458 PMQPVMYPPNYQSLPLSQDLP--------------QPQSTASQGGQNKKLAQVLASATPQMQKQV 508
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
613-764 |
1.76e-04 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 46.72 E-value: 1.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 613 SQLMGMHQQIVPSQGQMVQqqgtLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMtPPKQMLSQQGPQMMAPhnqm 692
Cdd:TIGR01628 369 AHLQDQFMQLQPRMRQLPM----GSPMGGAMGQPPYYGQGPQQQFNGQPLGWPRMSMMP-TPMGPGGPLRPNGLAP---- 439
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 768016694 693 MGPQGQVLLQQNPMIEQimtNQMQGNKQQFNTQNQSNVMPGPAQimrGPTPNMQGNMvQFTGQMSGQMLPQQ 764
Cdd:TIGR01628 440 MNAVRAPSRNAQNAAQK---PPMQPVMYPPNYQSLPLSQDLPQP---QSTASQGGQN-KKLAQVLASATPQM 504
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
923-1484 |
2.07e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.86 E-value: 2.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 923 DLNTPDTRPAgleeadqpPLPGEQGINLDNSGPKLPEFSNRP--PGYPS-QPVEQRPLQQMPPQLMQHVAPPPQPPQQQP 999
Cdd:PHA03247 2565 DRSVPPPRPA--------PRPSEPAVTSRARRPDAPPQSARPraPVDDRgDPRGPAPPSPLPPDTHAPDPPPPSPSPAAN 2636
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1000 QPQLPQQQQPPPPSQPQSQQQqqqqqqmmmmlmmqqdPKSVRLP--VSQNVHPPRGPLNPDSQRMPMQQSGSVPVmVSLQ 1077
Cdd:PHA03247 2637 EPDPHPPPTVPPPERPRDDPA----------------PGRVSRPrrARRLGRAAQASSPPQRPRRRAARPTVGSL-TSLA 2699
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1078 GPASVPPSPDKQRMPMPVNTPL--GSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEA-PSVPGGPNNmPSHVVLPQNQ 1154
Cdd:PHA03247 2700 DPPPPPPTPEPAPHALVSATPLppGPAAARQASPALPAAPAPPAVPAGPATPGGPARPArPPTTAGPPA-PAPPAAPAAG 2778
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1155 LMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVaAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLS 1234
Cdd:PHA03247 2779 PPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAAL-PPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVA 2857
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1235 PERLNASIAGLFPPQINIPLPPRPNLNRgfdqqglnpTTLKAIGQAPSNLTMNPSNFATPQTHKLDsvvvnSGKQSNSGA 1314
Cdd:PHA03247 2858 PGGDVRRRPPSRSPAAKPAAPARPPVRR---------LARPAVSRSTESFALPPDQPERPPQPQAP-----PPPQPQPQP 2923
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1315 TKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQ-NVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQ 1393
Cdd:PHA03247 2924 PPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPgRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSR 3003
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1394 NSTVSVAAVGGVVEDN-----KESLNVPQDSDCQNSQSRKEQVNIELkavpaqevkmvvpeDQSKKDGQPSDPNKLPSVE 1468
Cdd:PHA03247 3004 VSSWASSLALHEETDPppvslKQTLWPPDDTEDSDADSLFDSDSERS--------------DLEALDPLPPEPHDPFAHE 3069
|
570
....*....|....*.
gi 768016694 1469 ENKNLVSPAMREAPTS 1484
Cdd:PHA03247 3070 PDPATPEAGARESPSS 3085
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
190-497 |
2.37e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.47 E-value: 2.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 190 PPGGNVSSSMMAPGPNPELQPRtPRPASQSDamdPLLSGLHIQQQSHPSGSLAP-----PHHPMQPVSVNRQMNPANFPQ 264
Cdd:PHA03247 2690 PTVGSLTSLADPPPPPPTPEPA-PHALVSAT---PLPPGPAAARQASPALPAAPappavPAGPATPGGPARPARPPTTAG 2765
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 265 LQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHqqqqpqgirPQFTAPTQVPVPPGWNQLPSGALQPPPaqgsLGTMT 344
Cdd:PHA03247 2766 PPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPS---------PWDPADPPAAVLAPAAALPPAASPAGP----LPPPT 2832
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 345 ANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSL-QGGPSRVPTPL 423
Cdd:PHA03247 2833 SAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALpPDQPERPPQPQ 2912
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768016694 424 QQPHLTNKSPASSPssfqqgsPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVP-PNFMVM 497
Cdd:PHA03247 2913 APPPPQPQPQPPPP-------PQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAvPRFRVP 2980
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1101-1396 |
1.06e-03 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 44.14 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1101 SNSRKMVYQESPQNPSSSPLAEmaslpeASGSEAPSVPGGpnnMPSHVVLPQNQLM--MTGPK------PGPSPLSATQG 1172
Cdd:pfam05109 414 TTTHKVIFSKAPESTTTSPTLN------TTGFAAPNTTTG---LPSSTHVPTNLTApaSTGPTvstadvTSPTPAGTTSG 484
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1173 ATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQ-TPNNRPPS---TEPSE--ISLSPERLNASIAGLF 1246
Cdd:pfam05109 485 ASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTpTPNATSPTlgkTSPTSavTTPTPNATSPTPAVTT 564
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1247 P-PQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRR 1325
Cdd:pfam05109 565 PtPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSM 644
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 768016694 1326 SSPGSSRKTTPSPGRQN---SKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGlnPQNST 1396
Cdd:pfam05109 645 SLRPSSISETLSPSTSDnstSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTSQASG--PGNSS 716
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
385-492 |
1.81e-03 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 43.49 E-value: 1.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 385 SQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQ----QGSPASSPTVNQTQQQMGP 460
Cdd:pfam09770 211 AQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTILQrpqsPQPDPAQPSIQPQAQQFHQ 290
|
90 100 110
....*....|....*....|....*....|....
gi 768016694 461 RPPQNNPLP-QGFQQP-VSSPGRNPMVQQGNVPP 492
Cdd:pfam09770 291 QPPPVPVQPtQILQNPnRLSAARVGYPQNPQPGV 324
|
|
| SOBP |
pfam15279 |
Sine oculis-binding protein; SOBP is associated with syndromic and nonsyndromic intellectual ... |
1074-1288 |
2.45e-03 |
|
Sine oculis-binding protein; SOBP is associated with syndromic and nonsyndromic intellectual disability. It carries a zinc-finger of the zf-C2H2 type at the N-terminus, and a highly characteriztic C-terminal PhPhPhPhPhPh motif. The deduced 873-amino acid protein contains an N-terminal nuclear localization signal (NLS), followed by 2 FCS-type zinc finger motifs, a proline-rich region (PR1), a putative RNA-binding motif region, and a C-terminal NLS embedded in a second proline-rich motif. SOBP is expressed in various human tissues, including developing mouse brain at embryonic day 14. In postnatal and adult mouse brain SOBP is expressed in all neurons, with intense staining in the limbic system. Highest expression is in layer V cortical neurons, hippocampus, pyriform cortex, dorsomedial nucleus of thalamus, amygdala, and hypothalamus. Postnatal expression of SOBP in the limbic system corresponds to a time of active synaptogenesis. the family is also referred to as Jackson circler, JXC1. In seven affected siblings from a consanguineous Israeli Arab family with mental retardation, anterior maxillary protrusion, and strabismus mutations were found in this protein.
Pssm-ID: 464609 [Multi-domain] Cd Length: 325 Bit Score: 42.49 E-value: 2.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1074 VSLQGPASVPPSPDKQRMPMPVNTPLGS--NSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLP 1151
Cdd:pfam15279 91 ESVSPGPSSSASPSSSPTSSNSSKPLISvaSSSKLLAPKPHEPPSLPPPPLPPKKGRRHRPGLHPPLGRPPGSPPMSMTP 170
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90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 1152 QNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHhfPNVAAPTQTSRPKTPNRASPRPYYPQT-PNNRPP-----S 1225
Cdd:pfam15279 171 RGLLGKPQQHPPPSPLPAFMEPSSMPPPFLRPPPSIPQ--PNSPLSNPMLPGIGPPPKPPRNLGPPSnPMHRPPfsphhP 248
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 768016694 1226 TEPSEISLSPERLNASIAGLFPPQINIPLPPrpnLNRGFDQQGLNPTTLKAIGQAPSNLTMNP 1288
Cdd:pfam15279 249 PPPPTPPGPPPGLPPPPPRGFTPPFGPPFPP---VNMMPNPPEMNFGLPSLAPLVPPVTVLVP 308
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|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
182-548 |
2.94e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.00 E-value: 2.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 182 NNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGL----------------------HIQQQSHPSG 239
Cdd:PHA03247 2596 ARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPptvppperprddpapgrvsrprRARRLGRAAQ 2675
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 240 SLAPPHHP---------------MQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQP 304
Cdd:PHA03247 2676 ASSPPQRPrrraarptvgsltslADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPA 2755
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 305 QGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMqQQLQARPSLATVQTPSHPPPPYPFG 384
Cdd:PHA03247 2756 RPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPA-AVLAPAAALPPAASPAGPLPPPTSA 2834
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 385 SQQASQAHTNFPQMSNP-GQFTAPqmkslqGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPP 463
Cdd:PHA03247 2835 QPTAPPPPPGPPPPSLPlGGSVAP------GGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERP 2908
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016694 464 qnnPLPQGFQQPVSSPGRNPMVQQGNVPPnfmvmqqqPPNQGPQSLHPGLGAGQANPNFMQGQVPSTTATTPGNSGAPQL 543
Cdd:PHA03247 2909 ---PQPQAPPPPQPQPQPPPPPQPQPPPP--------PPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRF 2977
|
....*
gi 768016694 544 QANQN 548
Cdd:PHA03247 2978 RVPQP 2982
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