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Conserved domains on  [gi|767990226|ref|XP_011521514|]
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zinc finger protein 821 isoform X2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG2433 super family cl43687
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
260-334 2.13e-06

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


The actual alignment was detected with superfamily member COG2433:

Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 49.86  E-value: 2.13e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767990226 260 LRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRmRDREAKRLQRMQETDEQRARRLQRDREamRLKRANE 334
Cdd:COG2433  432 LEAELEEKDERIERLERELSEARSEERREIRKDREISR-LDREIERLERELEEERERIEELKRKLE--RLKELWK 503
 
Name Accession Description Interval E-value
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
260-334 2.13e-06

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 49.86  E-value: 2.13e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767990226 260 LRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRmRDREAKRLQRMQETDEQRARRLQRDREamRLKRANE 334
Cdd:COG2433  432 LEAELEEKDERIERLERELSEARSEERREIRKDREISR-LDREIERLERELEEERERIEELKRKLE--RLKELWK 503
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 261-358 2.25e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 46.66  E-value: 2.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  261 RRQNEPLEVRLQRLERERtakksrrdnetpeEREVRRMRDREAKRLQRM----QETDEQRARRLQRDREAMRLKRA---- 332
Cdd:pfam17380 427 AEQEEARQREVRRLEEER-------------AREMERVRLEEQERQQQVerlrQQEEERKRKKLELEKEKRDRKRAeeqr 493

                          90       100       110
                  ....*....|....*....|....*....|.
gi 767990226  333 -----NETPEKRQARLIREREAKRLKRRLEK 358
Cdd:pfam17380 494 rkileKELEERKQAMIEEERKRKLLEKEMEE 524
PTZ00121 PTZ00121
MAEBL; Provisional
 245-358 8.66e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.13  E-value: 8.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  245 RKLLEAQTP-SVRKWALRRQNEplEVR----LQRLERERTAKKSRRDNETPEEREVRRMRD-----REAKRLQRMQETDE 314
Cdd:PTZ00121 1176 KKAEAARKAeEVRKAEELRKAE--DARkaeaARKAEEERKAEEARKAEDAKKAEAVKKAEEakkdaEEAKKAEEERNNEE 1253

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 767990226  315 QRARRLQRDREAMRLKRANETPEKRQARLIREREAKRLKRRLEK 358
Cdd:PTZ00121 1254 IRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKK 1297
U2AF_lg TIGR01642
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ...
 275-387 8.96e-05

U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.


Pssm-ID: 273727 [Multi-domain]  Cd Length: 509  Bit Score: 44.50  E-value: 8.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  275 ERERTAKKSR-RDNETPEEREVRRMRDREAKR-------LQRMQETDEQRARRLQRDREAMRLK----RANETPEKRQAR 342
Cdd:TIGR01642   4 EPDREREKSRgRDRDRSSERPRRRSRDRSRFRdrhrrsrERSYREDSRPRDRRRYDSRSPRSLRyssvRRSRDRPRRRSR 83

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767990226  343 LI------REREAKRLKRRLEKMDMMLRAQFGQDPSAM----AALAAEMNFFQLP 387
Cdd:TIGR01642  84 SVrsieqhRRRLRDRSPSNQWRKDDKKRSLWDIKPPGYelvtADQAKASQVFSVP 138
mS26_PET12 cd23703
Saccharomyces cerevisiae mitochondrial small ribosomal subunit protein mS26 and similar ...
 268-360 9.95e-03

Saccharomyces cerevisiae mitochondrial small ribosomal subunit protein mS26 and similar proteins; mS26, also known as mitochondrial 37S ribosomal protein PET12, is a component of the mitochondrial small ribosomal subunit (mt-SSU) of Saccharomyces cerevisiae mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane. The family also includes a group of uncharacterized proteins from pezizomycotina, which show high sequence similarity with mS26.


Pssm-ID: 467916 [Multi-domain]  Cd Length: 179  Bit Score: 36.76  E-value: 9.95e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226 268 EVRLQRLERERTAKKSRRDNETPEER------EVRR--MRD---REAKRLQRMQETDEQRARRLQRDREAMRLKRANE-- 334
Cdd:cd23703   25 EEYIAKTTPEPKKEPKPKSPLSEYQEwkrkmaELRRqnLREglrELEERKLKTEELRAKRSERKQAERERALNAPEREde 104

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 767990226 335 -------------------TPEKRQARLiREREAKRLKRRLEKMD 360
Cdd:cd23703  105 rltlptiesallgplmrvrTDPEREERA-AKRRANREAKELAKKE 148
 
Name Accession Description Interval E-value
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
260-334 2.13e-06

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 49.86  E-value: 2.13e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767990226 260 LRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRmRDREAKRLQRMQETDEQRARRLQRDREamRLKRANE 334
Cdd:COG2433  432 LEAELEEKDERIERLERELSEARSEERREIRKDREISR-LDREIERLERELEEERERIEELKRKLE--RLKELWK 503
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
242-366 8.56e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.84  E-value: 8.56e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226 242 AAYRKLLEAQTPSVRKWALRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQ 321
Cdd:COG4717  119 EKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLA 198

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 767990226 322 RDREAMRLKRANETPEKRQARlireREAKRLKRRLEKMDMMLRAQ 366
Cdd:COG4717  199 EELEELQQRLAELEEELEEAQ----EELEELEEELEQLENELEAA 239
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 261-358 2.25e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 46.66  E-value: 2.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  261 RRQNEPLEVRLQRLERERtakksrrdnetpeEREVRRMRDREAKRLQRM----QETDEQRARRLQRDREAMRLKRA---- 332
Cdd:pfam17380 427 AEQEEARQREVRRLEEER-------------AREMERVRLEEQERQQQVerlrQQEEERKRKKLELEKEKRDRKRAeeqr 493

                          90       100       110
                  ....*....|....*....|....*....|.
gi 767990226  333 -----NETPEKRQARLIREREAKRLKRRLEK 358
Cdd:pfam17380 494 rkileKELEERKQAMIEEERKRKLLEKEMEE 524
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
259-364 3.04e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 46.00  E-value: 3.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226 259 ALRRQNEPLEVRlqRLERERTAKKSRRDNETPEEREVRRMRDR------EAKRLQRMQETDEQRARRLQRDREAMRLKRA 332
Cdd:COG2433  381 ALEELIEKELPE--EEPEAEREKEHEERELTEEEEEIRRLEEQverleaEVEELEAELEEKDERIERLERELSEARSEER 458

                         90       100       110
                 ....*....|....*....|....*....|..
gi 767990226 333 NETPEKRQARlIREREAKRLKRRLEKMDMMLR 364
Cdd:COG2433  459 REIRKDREIS-RLDREIERLERELEEERERIE 489
PTZ00121 PTZ00121
MAEBL; Provisional
 245-358 8.66e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.13  E-value: 8.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  245 RKLLEAQTP-SVRKWALRRQNEplEVR----LQRLERERTAKKSRRDNETPEEREVRRMRD-----REAKRLQRMQETDE 314
Cdd:PTZ00121 1176 KKAEAARKAeEVRKAEELRKAE--DARkaeaARKAEEERKAEEARKAEDAKKAEAVKKAEEakkdaEEAKKAEEERNNEE 1253

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 767990226  315 QRARRLQRDREAMRLKRANETPEKRQARLIREREAKRLKRRLEK 358
Cdd:PTZ00121 1254 IRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKK 1297
U2AF_lg TIGR01642
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ...
 275-387 8.96e-05

U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.


Pssm-ID: 273727 [Multi-domain]  Cd Length: 509  Bit Score: 44.50  E-value: 8.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  275 ERERTAKKSR-RDNETPEEREVRRMRDREAKR-------LQRMQETDEQRARRLQRDREAMRLK----RANETPEKRQAR 342
Cdd:TIGR01642   4 EPDREREKSRgRDRDRSSERPRRRSRDRSRFRdrhrrsrERSYREDSRPRDRRRYDSRSPRSLRyssvRRSRDRPRRRSR 83

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767990226  343 LI------REREAKRLKRRLEKMDMMLRAQFGQDPSAM----AALAAEMNFFQLP 387
Cdd:TIGR01642  84 SVrsieqhRRRLRDRSPSNQWRKDDKKRSLWDIKPPGYelvtADQAKASQVFSVP 138
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
249-370 9.43e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.46  E-value: 9.43e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226 249 EAQTPSVRKWALRRQNEPLEVRLQRLERErtAKKSRRDNETpEEREVRRmRDREAKRLQ-RMQETDEQRARRLQRDREAM 327
Cdd:COG2433  393 EEPEAEREKEHEERELTEEEEEIRRLEEQ--VERLEAEVEE-LEAELEE-KDERIERLErELSEARSEERREIRKDREIS 468

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 767990226 328 RLKRANETPEKRQARLirEREAKRLKRRLEKMDMMLRAQFGQD 370
Cdd:COG2433  469 RLDREIERLERELEEE--RERIEELKRKLERLKELWKLEHSGE 509
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 259-357 9.53e-05

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 44.14  E-value: 9.53e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  259 ALRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAK-RLQRMQETDEQRARRLQRDREAMRLKRANETPE 337
Cdd:pfam13868 137 EEQAEWKELEKEEEREEDERILEYLKEKAEREEEREAEREEIEEEKeREIARLRAQQEKAQDEKAERDELRAKLYQEEQE 216

                          90       100
                  ....*....|....*....|
gi 767990226  338 KRQARLIREREAKRLKRRLE 357
Cdd:pfam13868 217 RKERQKEREEAEKKARQRQE 236
CCDC47 pfam07946
PAT complex subunit CCDC47; This family represents CCDC47 proteins which are a component of ...
 289-354 1.07e-04

PAT complex subunit CCDC47; This family represents CCDC47 proteins which are a component of the PAT complex, an endoplasmic reticulum (ER)-resident membrane multiprotein complex that facilitates multi-pass membrane proteins insertion into membranes. The PAT complex, formed by CCDC47 and Asterix proteins, acts as an intramembrane chaperone by directly interacting with nascent transmembrane domains (TMDs), releasing its substrates upon correct folding, and is needed for optimal biogenesis of multi-pass membrane proteins. CCDC47 is required to maintain the stability of Asterix. CCDC47 is associated with various membrane-associated processes and is component of a ribosome-associated ER translocon complex involved in multi-pass membrane protein transport into the ER membrane and biogenesis. It is also involved in the regulation of calcium ion homeostasis in the ER, being also required for proper protein degradation via the ERAD (ER-associated degradation) pathway.


Pssm-ID: 462322  Cd Length: 323  Bit Score: 43.71  E-value: 1.07e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  289 TPEERE-VRRMRDREAKRLQRMQETDEQRARRLQRD---REAMRLKRANETPEKRQARLIREREaKRLKR 354
Cdd:pfam07946 255 RPEALKkAKKTREEEIEKIKKAAEEERAEEAQEKKEeakKKEREEKLAKLSPEEQRKYEEKERK-KEQRK 323
PTZ00121 PTZ00121
MAEBL; Provisional
 262-358 4.05e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 4.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  262 RQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRmrdreAKRLQRMQETDEQRARRLQRD-----REAMRLKRANETP 336
Cdd:PTZ00121 1613 KKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKK-----AEELKKAEEENKIKAAEEAKKaeedkKKAEEAKKAEEDE 1687

                          90       100
                  ....*....|....*....|..
gi 767990226  337 EKRQARLIREREAKRLKRRLEK 358
Cdd:PTZ00121 1688 KKAAEALKKEAEEAKKAEELKK 1709
PTZ00121 PTZ00121
MAEBL; Provisional
 249-358 4.64e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 4.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  249 EAQTPSVRKWALRRQNEplevrLQRLERERTAKKSRRDNETPEEREVRRM----RDREAKRLQRMQETDEqrARRLQRDR 324
Cdd:PTZ00121 1110 KAEEARKAEEAKKKAED-----ARKAEEARKAEDARKAEEARKAEDAKRVeiarKAEDARKAEEARKAED--AKKAEAAR 1182

                          90       100       110
                  ....*....|....*....|....*....|....
gi 767990226  325 EAMRLKRANETPEKRQARLIREREAKRLKRRLEK 358
Cdd:PTZ00121 1183 KAEEVRKAEELRKAEDARKAEAARKAEEERKAEE 1216
CCDC50_N pfam15295
Coiled-coil domain-containing protein 50 N-terminus;
275-355 5.03e-04

Coiled-coil domain-containing protein 50 N-terminus;


Pssm-ID: 464621 [Multi-domain]  Cd Length: 126  Bit Score: 39.71  E-value: 5.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  275 ERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQRD--REAMRLKRANETPEKrQARLIREREAKRL 352
Cdd:pfam15295  44 QRNQLVQNDIRVAKQLQEEEELQAQTLFQRRLAQLEEQDEEIAKEIQEElqREAEERRRREEEDEE-IARQLQERERERE 122


                  ...
gi 767990226  353 KRR 355
Cdd:pfam15295 123 RRR 125
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 267-367 5.90e-04

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 41.83  E-value: 5.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  267 LEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREAMRLKRANETPEKRQ---ARL 343
Cdd:pfam13868 158 LEYLKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKArqrQEL 237

                          90       100
                  ....*....|....*....|....*
gi 767990226  344 IREREA-KRLKRRLEKMDMMLRAQF 367
Cdd:pfam13868 238 QQAREEqIELKERRLAEEAEREEEE 262
Caldesmon pfam02029
Caldesmon;
272-361 6.26e-04

Caldesmon;


Pssm-ID: 460421 [Multi-domain]  Cd Length: 495  Bit Score: 41.78  E-value: 6.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  272 QRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRlQRDREAMRLKRANETPEkRQARLirEREAKR 351
Cdd:pfam02029 242 VFLEAEQKLEELRRRRQEKESEEFEKLRQKQQEAELELEELKKKREER-RKLLEEEEQRRKQEEAE-RKLRE--EEEKRR 317

                          90
                  ....*....|
gi 767990226  352 LKRRLEKMDM 361
Cdd:pfam02029 318 MKEEIERRRA 327
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 260-366 6.28e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.23  E-value: 6.28e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226 260 LRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREAMRLKRANETpEKR 339
Cdd:COG1196  307 LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE-ELA 385

                         90       100
                 ....*....|....*....|....*..
gi 767990226 340 QARLIREREAKRLKRRLEKMDMMLRAQ 366
Cdd:COG1196  386 EELLEALRAAAELAAQLEELEEAEEAL 412
TolA COG3064
Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];
261-358 6.84e-04

Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442298 [Multi-domain]  Cd Length: 485  Bit Score: 41.95  E-value: 6.84e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226 261 RRQNEPLEVRLQRLERERTAKKSRR---DNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREAMRLKRANETPE 337
Cdd:COG3064    8 KAAEAAAQERLEQAEAEKRAAAEAEqkaKEEAEEERLAELEAKRQAEEEAREAKAEAEQRAAELAAEAAKKLAEAEKAAA 87

                         90       100
                 ....*....|....*....|.
gi 767990226 338 KRQARLirEREAKRLKRRLEK 358
Cdd:COG3064   88 EAEKKA--AAEKAKAAKEAEA 106
Nop53 pfam07767
Nop53 (60S ribosomal biogenesis); This nucleolar family of proteins are involved in 60S ...
 268-358 7.66e-04

Nop53 (60S ribosomal biogenesis); This nucleolar family of proteins are involved in 60S ribosomal biogenesis. They are specifically involved in the processing beyond the 27S stage of 25S rRNA maturation. This family contains sequences that bear similarity to the glioma tumour suppressor candidate region gene 2 protein (p60). This protein has been found to interact with herpes simplex type 1 regulatory proteins.


Pssm-ID: 462259 [Multi-domain]  Cd Length: 353  Bit Score: 41.51  E-value: 7.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  268 EVRLQRLERE----RTAKKSRRDNETPEEREVRRM----RDREAKRLQRMQETDEQRARRLQRdREAMRLKRANETPEKR 339
Cdd:pfam07767 206 EAEKKRLKEEekleRVLEKIAESAATAEAREEKRKtkaqRNKEKRRKEEEREAKEEKALKKKL-AQLERLKEIAKEIAEK 284

                          90
                  ....*....|....*....
gi 767990226  340 QARLIREREAKRLKRRLEK 358
Cdd:pfam07767 285 EKEREEKAEARKREKRKKK 303
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 270-383 1.88e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 40.69  E-value: 1.88e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226 270 RLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREAMRLKRANETPEKRQARLIREREA 349
Cdd:COG1196  285 EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE 364

                         90       100       110
                 ....*....|....*....|....*....|....
gi 767990226 350 KRLKRRLEKMDMMLRAQFGQDPSAMAALAAEMNF 383
Cdd:COG1196  365 EALLEAEAELAEAEEELEELAEELLEALRAAAEL 398
SF-CC1 TIGR01622
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors ...
 284-358 3.08e-03

splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors including the Pad-1 protein (N. crassa), CAPER (M. musculus) and CC1.3 (H.sapiens). These proteins are characterized by an N-terminal arginine-rich, low complexity domain followed by three (or in the case of 4 H. sapiens paralogs, two) RNA recognition domains (rrm: pfam00706). These splicing factors are closely related to the U2AF splicing factor family (TIGR01642). A homologous gene from Plasmodium falciparum was identified in the course of the analysis of that genome at TIGR and was included in the seed.


Pssm-ID: 273721 [Multi-domain]  Cd Length: 494  Bit Score: 39.52  E-value: 3.08e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767990226  284 RRDNETPEEREVRRMRDREAKRlqrmqETDEQRARRLQRDREAMRLKRANETPEKRQARLIREREAKRLKRRLEK 358
Cdd:TIGR01622   2 YRDRERERLRDSSSAGDRDRRR-----DKGRERSRDRSRDRERSRSRRRDRHRDRDYYRGRERRSRSRRPNRRYR 71
PRK12705 PRK12705
hypothetical protein; Provisional
 255-366 3.33e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 39.69  E-value: 3.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226 255 VRKWALRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREakrlqrmqetdEQRARRLQRDREAMRLKRANE 334
Cdd:PRK12705  23 VLLKKRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQ-----------EARREREELQREEERLVQKEE 91

                         90       100       110
                 ....*....|....*....|....*....|..
gi 767990226 335 TPEKRQARLirereaKRLKRRLEKMDMMLRAQ 366
Cdd:PRK12705  92 QLDARAEKL------DNLENQLEEREKALSAR 117
MAP7 pfam05672
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...
 245-357 3.64e-03

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.


Pssm-ID: 461709 [Multi-domain]  Cd Length: 153  Bit Score: 37.71  E-value: 3.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  245 RKLLEAQTPSVRKWALRRQNEplEVRLQRLERERTAKKSRRDNETPEER----EVRRMRDREAKRLQRMQETDEQRARRL 320
Cdd:pfam05672  33 ERLEKEEEERLRKEELRRRAE--EERARREEEARRLEEERRREEEERQRkaeeEAEEREQREQEEQERLQKQKEEAEAKA 110

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 767990226  321 QRDREAMRLKRANETPEKRQARLIRereakrlKRRLE 357
Cdd:pfam05672 111 REEAERQRQEREKIMQQEEQERLER-------KKRIE 140
PRK00247 PRK00247
putative inner membrane protein translocase component YidC; Validated
 256-341 3.89e-03

putative inner membrane protein translocase component YidC; Validated


Pssm-ID: 178945 [Multi-domain]  Cd Length: 429  Bit Score: 39.45  E-value: 3.89e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226 256 RKWALRRQN----------EPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREA---KRLQRMQETDEQRARRLQR 322
Cdd:PRK00247 304 FLWTLRRNRlrmiitpwraPELHAENAEIKKTRTAEKNEAKARKKEIAQKRRAAEREInreARQERAAAMARARARRAAV 383

                         90
                 ....*....|....*....
gi 767990226 323 DREAMRLKRANETPEKRQA 341
Cdd:PRK00247 384 KAKKKGLIDASPNEDTPSE 402
DUF4670 pfam15709
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...
 261-366 4.03e-03

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.


Pssm-ID: 464815 [Multi-domain]  Cd Length: 522  Bit Score: 39.16  E-value: 4.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  261 RRQNEPLEVRLQRLERERtakksRRDNEtpEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREAMRLKRANETPEKR- 339
Cdd:pfam15709 383 QRRFEEIRLRKQRLEEER-----QRQEE--EERKQRLQLQAAQERARQQQEEFRRKLQELQRKKQQEEAERAEAEKQRQk 455

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 767990226  340 ---------QARLIREREAKRLKRRLEKMDMMLRAQ 366
Cdd:pfam15709 456 elemqlaeeQKRLMEMAEEERLEYQRQKQEAEEKAR 491
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
267-369 4.21e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 39.23  E-value: 4.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226 267 LEVRLQRLERERTAKKSRRDNETP-------EEREVRRMRDREAKRLQRMQETD----EQRARRLQRDREAMRlKRANET 335
Cdd:COG3206  268 LRAQLAELEAELAELSARYTPNHPdvialraQIAALRAQLQQEAQRILASLEAElealQAREASLQAQLAQLE-ARLAEL 346

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 767990226 336 PEKRQ--ARLIREREAKR-----LKRRLEKMDMMLRAQFGQ 369
Cdd:COG3206  347 PELEAelRRLEREVEVARelyesLLQRLEEARLAEALTVGN 387
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 249-366 4.39e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 39.34  E-value: 4.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  249 EAQTPSVRKWALRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREV---RRMRDR-EAKRLQRM---QETDEQRARRLQ 321
Cdd:pfam17380 431 EARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLeleKEKRDRkRAEEQRRKileKELEERKQAMIE 510

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 767990226  322 RDREAMRLKRANETPEKRQARLIREREAKRLKRRLEKMDMMLRAQ 366
Cdd:pfam17380 511 EERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQ 555
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 245-360 4.54e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 39.34  E-value: 4.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  245 RKLLEAQTpsVRKWALRRQ--------------NEPLEvRLQRLERERTAKKSRRDN---ETPEEREVRRMR-------- 299
Cdd:pfam17380 316 RKLEEAEK--ARQAEMDRQaaiyaeqermamerERELE-RIRQEERKRELERIRQEEiamEISRMRELERLQmerqqkne 392

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767990226  300 ----DREAKRLQRMQETDEQRARRLQRdREAMRLKRANETPEKRQARLIREREAKRLKR-RLEKMD 360
Cdd:pfam17380 393 rvrqELEAARKVKILEEERQRKIQQQK-VEMEQIRAEQEEARQREVRRLEEERAREMERvRLEEQE 457
DUF4670 pfam15709
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...
 261-352 4.55e-03

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.


Pssm-ID: 464815 [Multi-domain]  Cd Length: 522  Bit Score: 39.16  E-value: 4.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  261 RRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMR-DREAKRLQRMQEtdEQRARRLQRDREAMRlKRANETPEKR 339
Cdd:pfam15709 422 RQQQEEFRRKLQELQRKKQQEEAERAEAEKQRQKELEMQlAEEQKRLMEMAE--EERLEYQRQKQEAEE-KARLEAEERR 498

                          90
                  ....*....|...
gi 767990226  340 QarliREREAKRL 352
Cdd:pfam15709 499 Q----KEEEAARL 507
CCDC66 pfam15236
Coiled-coil domain-containing protein 66; This protein family, named Coiled-coil ...
 247-358 4.71e-03

Coiled-coil domain-containing protein 66; This protein family, named Coiled-coil domain-containing protein 66 (CCDC) refers to a protein domain found in eukaryotes, and is approximately 160 amino acids in length. CCDC66 protein is detected mainly in the inner segments of photoreceptors in many vertebrates including mice and humans. It has been found in dogs, that a mutation in the CCDC66 gene causes generalized progressive retinal atrophy (gPRA). This shows that the protein encoded for by this gene is vital for healthy vision and guards against photoreceptor cell degeneration. The structure of CCDC66 proteins includes a heptad repeat pattern which contains at least one coiled-coil domain. There are at least two or more alpha-helices which form a cable-like structure.


Pssm-ID: 434558 [Multi-domain]  Cd Length: 154  Bit Score: 37.47  E-value: 4.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226  247 LLEAQTPSVRKWALRRQNEPLEVRLQRLERERTAKK---SRRDNEtpEEREVRRMRdreaKRLQRMQETDEQRARRLQRD 323
Cdd:pfam15236  38 LLDPAQLEERERKRQKALEHQNAIKKQLEEKERQKKleeERRRQE--EQEEEERLR----REREEEQKQFEEERRKQKEK 111

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 767990226  324 REAMRLKRAN--ETPEKRQARLIREREAKRLKRRLEK 358
Cdd:pfam15236 112 EEAMTRKTQAllQAMQKAQELAQRLKQEQRIRELAEK 148
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 259-358 5.78e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 39.15  E-value: 5.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226 259 ALRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETD---EQRARRLQRDREAMRLKRANEt 335
Cdd:COG1196  236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEyelLAELARLEQDIARLEERRREL- 314

                         90       100
                 ....*....|....*....|...
gi 767990226 336 pEKRQARLIREREAKRLKRRLEK 358
Cdd:COG1196  315 -EERLEELEEELAELEEELEELE 336
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 259-359 6.35e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 38.76  E-value: 6.35e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226 259 ALRRQNEPLEVRLQRLERERTAKKSRRDNETpEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREAMRLKRANETPEK 338
Cdd:COG1196  673 ALLEAEAELEELAERLAEEELELEEALLAEE-EEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751

                         90       100
                 ....*....|....*....|.
gi 767990226 339 RQARLIREREAKRLKRRLEKM 359
Cdd:COG1196  752 ALEELPEPPDLEELERELERL 772
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 259-358 6.46e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 38.76  E-value: 6.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226 259 ALRRQNEPLEVRLQRLERERTAKKSRRDNEtpEEREVRRMRDREAKR-----LQRMQETDEQRARRLQRDREAMRLKRAN 333
Cdd:COG1196  355 EAEAELAEAEEALLEAEAELAEAEEELEEL--AEELLEALRAAAELAaqleeLEEAEEALLERLERLEEELEELEEALAE 432

                         90       100
                 ....*....|....*....|....*
gi 767990226 334 ETPEKRQARLIREREAKRLKRRLEK 358
Cdd:COG1196  433 LEEEEEEEEEALEEAAEEEAELEEE 457
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 267-379 7.88e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 38.76  E-value: 7.88e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226 267 LEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQETDEQRARRLQRDREamrLKRANETPEKRQARLIRE 346
Cdd:COG1196  409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE---LLEEAALLEAALAELLEE 485

                         90       100       110
                 ....*....|....*....|....*....|...
gi 767990226 347 REAKRLKRRLEKMDMMLRAQFGQDPSAMAALAA 379
Cdd:COG1196  486 LAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
242-317 8.79e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 38.46  E-value: 8.79e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226 242 AAYRKLLEAQTPSVRKwALRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRM-RDREAKR------LQRMQETDE 314
Cdd:COG3206  301 AALRAQLQQEAQRILA-SLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLeREVEVARelyeslLQRLEEARL 379


                 ...
gi 767990226 315 QRA 317
Cdd:COG3206  380 AEA 382
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 259-364 9.64e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 38.50  E-value: 9.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226   259 ALRRQNEPLEVRLQRLERERTAKKSRRDNETPEEREVRRMRDREAKRLQRMQ-ETDEQRARRLQRDREAM--RLKRA-NE 334
Cdd:TIGR02168  390 QLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAElEELEEELEELQEELERLeeALEELrEE 469

                           90       100       110
                   ....*....|....*....|....*....|
gi 767990226   335 TPEKRQARLIREREAKRLKRRLEKMDMMLR 364
Cdd:TIGR02168  470 LEEAEQALDAAERELAQLQARLDSLERLQE 499
mS26_PET12 cd23703
Saccharomyces cerevisiae mitochondrial small ribosomal subunit protein mS26 and similar ...
 268-360 9.95e-03

Saccharomyces cerevisiae mitochondrial small ribosomal subunit protein mS26 and similar proteins; mS26, also known as mitochondrial 37S ribosomal protein PET12, is a component of the mitochondrial small ribosomal subunit (mt-SSU) of Saccharomyces cerevisiae mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane. The family also includes a group of uncharacterized proteins from pezizomycotina, which show high sequence similarity with mS26.


Pssm-ID: 467916 [Multi-domain]  Cd Length: 179  Bit Score: 36.76  E-value: 9.95e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767990226 268 EVRLQRLERERTAKKSRRDNETPEER------EVRR--MRD---REAKRLQRMQETDEQRARRLQRDREAMRLKRANE-- 334
Cdd:cd23703   25 EEYIAKTTPEPKKEPKPKSPLSEYQEwkrkmaELRRqnLREglrELEERKLKTEELRAKRSERKQAERERALNAPEREde 104

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 767990226 335 -------------------TPEKRQARLiREREAKRLKRRLEKMD 360
Cdd:cd23703  105 rltlptiesallgplmrvrTDPEREERA-AKRRANREAKELAKKE 148
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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