endosome/lysosome-associated apoptosis and autophagy regulator family member 2 isoform X2 [Homo sapiens]
Protein Classification
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| Ephrin_rec_like | pfam07699 | Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ... |
347-377 | 2.29e-04 | ||
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity. : Pssm-ID: 429604 [Multi-domain] Cd Length: 48 Bit Score: 39.64 E-value: 2.29e-04
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| Name | Accession | Description | Interval | E-value | ||
| Ephrin_rec_like | pfam07699 | Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ... |
347-377 | 2.29e-04 | ||
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity. Pssm-ID: 429604 [Multi-domain] Cd Length: 48 Bit Score: 39.64 E-value: 2.29e-04
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| TNFRSF19L | cd13419 | tumor necrosis factor receptor superfamily member 19-like (TNFRSF19L), also known as receptor ... |
340-372 | 9.30e-03 | ||
tumor necrosis factor receptor superfamily member 19-like (TNFRSF19L), also known as receptor expressed in lymphoid tissues (RELT); TNFRSF19L (also known as receptor expressed in lymphoid tissues (RELT)) is especially abundant in hematologic tissues and can stimulate the proliferation of T-cells. It serves as a substrate for the closely related kinases, odd-skipped related transcription factor 1 (OSR1) and STE20/SPS1-related proline/alanine-rich kinase (SPAK); RELT binds SPAK and uses it to mediate p38 and JNK activation, rather than rely on the canonical TRAF pathways for its function. RELT is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. It interacts with phospholipid scramblase 1 (PLSCR1), an interferon-inducible protein that mediates antiviral activity against DNA and RNA viruses; PLSCR1 is a regulator of hepatitis B virus X (HBV X) protein. RELT and PLSCR1 co-localize in intracellular regions of human embryonic kidney-293 cells, with RELT over-expression appearing to alter the localization of PLSCR1. Pssm-ID: 276924 Cd Length: 91 Bit Score: 36.62 E-value: 9.30e-03
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| Name | Accession | Description | Interval | E-value | ||
| Ephrin_rec_like | pfam07699 | Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ... |
347-377 | 2.29e-04 | ||
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity. Pssm-ID: 429604 [Multi-domain] Cd Length: 48 Bit Score: 39.64 E-value: 2.29e-04
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| TNFRSF19L | cd13419 | tumor necrosis factor receptor superfamily member 19-like (TNFRSF19L), also known as receptor ... |
340-372 | 9.30e-03 | ||
tumor necrosis factor receptor superfamily member 19-like (TNFRSF19L), also known as receptor expressed in lymphoid tissues (RELT); TNFRSF19L (also known as receptor expressed in lymphoid tissues (RELT)) is especially abundant in hematologic tissues and can stimulate the proliferation of T-cells. It serves as a substrate for the closely related kinases, odd-skipped related transcription factor 1 (OSR1) and STE20/SPS1-related proline/alanine-rich kinase (SPAK); RELT binds SPAK and uses it to mediate p38 and JNK activation, rather than rely on the canonical TRAF pathways for its function. RELT is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. It interacts with phospholipid scramblase 1 (PLSCR1), an interferon-inducible protein that mediates antiviral activity against DNA and RNA viruses; PLSCR1 is a regulator of hepatitis B virus X (HBV X) protein. RELT and PLSCR1 co-localize in intracellular regions of human embryonic kidney-293 cells, with RELT over-expression appearing to alter the localization of PLSCR1. Pssm-ID: 276924 Cd Length: 91 Bit Score: 36.62 E-value: 9.30e-03
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