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Conserved domains on  [gi|1370486745|ref|XP_011511987|]
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protein furry homolog-like isoform X14 [Homo sapiens]

Protein Classification

furry family protein( domain architecture ID 10624858)

furry family protein such as Drosophila melanogaster protein furry (Fry), which is part of the trc/fry complex involved in maintaining the integrity of polarized cell extensions during morphogenesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MOR2-PAG1_N pfam14222
Cell morphogenesis N-terminal; This family is the conserved N-terminal region of proteins that ...
 209-756 0e+00

Cell morphogenesis N-terminal; This family is the conserved N-terminal region of proteins that are involved in cell morphogenesis.


:

Pssm-ID: 464107  Cd Length: 554  Bit Score: 619.98  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  209 ERRDLAVDFIFCLVLVEVLKQIPVHPVPDPLVHEVLNLAFKHFKHKEGYSGTNTGNVHIIADLYAEVIGVLAQSKFQAVR 288
Cdd:pfam14222    1 ERKSLASIYILCRVLIEIVKQSPLDALTEELGDKLEEIVFGQLKTADPDQLSSSPNRSANWNLFAELLGVLSEIRFVSVS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  289 KKFVTELKELRQKEQSPHVVQSVISLIMGMKFFRVKMYPVEDFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILIPV 368
Cdd:pfam14222   81 DRFIAELEKLPKGLSSKDLEAKIELLIRGMRYLRIKVYPEEAFEESADFMQSLAKFFLNAHGQRVKHAYAEVLVELLLPV 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  369 AAAVKNEVNVPCLKNFVEMLYQTTFELSSRKKHSLALYPLITCLLCVSQKQFFLNNWHIFLQNCLSHLkmpsnnsirkqi 448
Cdd:pfam14222  161 AATATAEVNHPKWKEAVELLYPRAAKMASKPRHWNVAFPLVTTLLCVSPKEFFLSNWLSLIESLISKL------------ 228

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  449 etlqnKDPKMSRVALESLYRLLWVYVIRIKcESNTVTQSRLMSIVSALFPKGSRSVVPRDTPLNIFVKIIQFIAQERLDF 528
Cdd:pfam14222  229 -----KDKTTRPVALQGLSRLLWVYLYRCT-ESLNTTTRKLESILKLLFPPGKKTWLPADPPLDPLVQIIRFIGFKHPDF 302

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  529 AMKEIIFDLLSVG--KSTKTFTINPERMNIGLRVFLVIADSLQQKDGEPPMPTTGVILPSGN--TLRVKKIFLNKTlTDE 604
Cdd:pfam14222  303 CFENIIFPLLNADlfNGLKLENLNPERMIIGIRAFLAILSDLEKGEQRPPFPQSFGTLPSPSssALRSKEENLSRP-VDT 381

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  605 EAKVIGMSVYYPQVRKALDSILRHLDKEVGRPM-------------CMTSVQMSNKEPED-MITGERKPKIDLFRTCIAA 670
Cdd:pfam14222  382 LALSEGIKDYYERFCKILGKILILCDNTFGGQAvldekfssptpktPISETFNFSRRPDDnAYDGQRQPFYELLHTAVQA 461

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  671 IPRLIPDGMSRTDLIELLARLTIHMDEELRALAFNTLQALMLdfPDWREDVLSGFVYFIV---------REVTDVHPTLL 741
Cdd:pfam14222  462 IPRCLPSSIPFNSLIELLCRGTVHVDPNIAESAAQALKRIAR--PSHAQQVITGFARFIFnfddrystmSDGGMLGPGHI 539

                          570
                   ....*....|....*
gi 1370486745  742 DNAVKMLVQLINQWK 756
Cdd:pfam14222  540 ESLLKLYVELLEIWI 554
MOR2-PAG1_mid super family cl20509
Cell morphogenesis central region; This family is the conserved central region of proteins ...
 788-1553 1.68e-29

Cell morphogenesis central region; This family is the conserved central region of proteins that are involved in cell morphogenesis.


The actual alignment was detected with superfamily member pfam14228:

Pssm-ID: 433790 [Multi-domain]  Cd Length: 1113  Bit Score: 128.22  E-value: 1.68e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  788 SNVFHV--VEGFALVILCSSRPATRRLAVSVLREIRALFALLEIPKGDDELAIDVMDRLSPSILESFIHLTGADQTTLLY 865
Cdd:pfam14228    1 TNEFRPsgLDAVGLIFLSSVDVQIRHTALELLRCVRALYNDLRDMSSKERSDVSWKNNKEPIFIIDVFEENGDDIVQQCY 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  866 CPSSIDLQTLAEWNSSPISHQFDVISPShiwifahvtQGQDPWIISLSSFLKQENlpKHCSTAVSYAWMFAYTRLQLLSP 945
Cdd:pfam14228   81 WDSGRPYDMRRESDAIPPDLTLQSILES---------PDKGRWARCLSELVKYAA--ELCPSSVQEARLEVVQRLAQITP 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  946 qVDINSpinakKVNTTTSSDSYIGLWRNYLILCCSaatsssstsagsvrCsPPETlasTPDSGYSidskiigipSPSSLF 1025
Cdd:pfam14228  150 -VELGG-----KAHQSQDADNKLDQWLLYSMFACS--------------C-PPDD---VEDTKSH---------SAKELY 196

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1026 KHIVPMMRSESMEITESLVLGLGRTNPGAFRELIEELHPIIKEA---LERRPENMKRRRRRDILRVQLVRIFELLAD--- 1099
Cdd:pfam14228  197 HLIFPSLKSGSETHIHAATLALGHSHLEVCEPMFGELRSFLDEVateTESKPKWKSQKARREELRVHVANIYRMVAEnfw 276

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1100 AGVISHSASGGLdnetHFLNntLLEyvDLTRQLLEAENEKDSDtLKDIRCHFSALVANIIQNVpVHQRRSIFPQQSlRHS 1179
Cdd:pfam14228  277 PGMLIRKPVFRL----HVLK--FIE--DTVRYITTSPLENFQD-LQPLRFALASVLRSLAPEF-VKSKSERFDPRT-RKR 345

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1180 LFMLFSHWAGPFSIMFT---------PLDRYS------------------DRNMQINRHQYCALKAMSAVLCcGPVADNV 1232
Cdd:pfam14228  346 LFDLLASWCDDTGTVWSqdgvsdyrrEVERYKssqnsrskdsvdkisfdkEVNEQVEAIQWIAMNAMAALLY-GPCFDDN 424

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1233 GLSSDGYLYKWLDNILD------------------------------SLDKKVHQLGCEAVTL-------LLELNPDqsn 1275
Cdd:pfam14228  425 ARKMSGRVIAWINGLFLepaprapfgyspadprtpsyskfagegvrgLGGKDRHRGGPLRVHLakvalknLLQTNLD--- 501

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1276 LMYWAVDRCYTGSGRVAAGCFKAIANVFQNRDY-QCDTVMLLNLILFKAADSSRSIYEVAMQLLQILEPKmfRYAHKLEV 1354
Cdd:pfam14228  502 LFPACIDQCYSSDASIADGYFSVLAEVYMRQEIpRCDIQRLLSLILYKVVDPSRRIRDDALQMLETLSVR--EWAEDGEE 579

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1355 QRTDGVLSQLSPLPHLYSVSYYQLSEELARAYPELTLAIFSEISQRIQTA--HPAGRQVmLHYLLPWMNNIELVDLKplp 1432
Cdd:pfam14228  580 GTGRYRAAVVGNLPDSYQQFQYKLSAKLAKDHPELSELLCEEIMQRQLDAvdIIAQHQV-LTCMAPWIENLNFLKLW--- 655

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1433 tarrhdededDSlkdrelmvtsrrwlrgeGWgspqaTAMVLNNLMYMTAKYGDELAwSEVENVWTTLADGwPKNLKIILH 1512
Cdd:pfam14228  656 ----------ES-----------------GW-----SERLLKSLYYVTWRHGDQFP-DEIEKLWRTIASK-PRNISPVLD 701

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1370486745 1513 FLIS--ICGVNSEPS---------LLPYVKKVIVYLGRDKTMQLLEELVSEL 1553
Cdd:pfam14228  702 FLISkgIEDCDSNASaeitgafatYFSVAKRVSLYLARICPQQTIDHLVYEL 753
 
Name Accession Description Interval E-value
MOR2-PAG1_N pfam14222
Cell morphogenesis N-terminal; This family is the conserved N-terminal region of proteins that ...
 209-756 0e+00

Cell morphogenesis N-terminal; This family is the conserved N-terminal region of proteins that are involved in cell morphogenesis.


Pssm-ID: 464107  Cd Length: 554  Bit Score: 619.98  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  209 ERRDLAVDFIFCLVLVEVLKQIPVHPVPDPLVHEVLNLAFKHFKHKEGYSGTNTGNVHIIADLYAEVIGVLAQSKFQAVR 288
Cdd:pfam14222    1 ERKSLASIYILCRVLIEIVKQSPLDALTEELGDKLEEIVFGQLKTADPDQLSSSPNRSANWNLFAELLGVLSEIRFVSVS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  289 KKFVTELKELRQKEQSPHVVQSVISLIMGMKFFRVKMYPVEDFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILIPV 368
Cdd:pfam14222   81 DRFIAELEKLPKGLSSKDLEAKIELLIRGMRYLRIKVYPEEAFEESADFMQSLAKFFLNAHGQRVKHAYAEVLVELLLPV 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  369 AAAVKNEVNVPCLKNFVEMLYQTTFELSSRKKHSLALYPLITCLLCVSQKQFFLNNWHIFLQNCLSHLkmpsnnsirkqi 448
Cdd:pfam14222  161 AATATAEVNHPKWKEAVELLYPRAAKMASKPRHWNVAFPLVTTLLCVSPKEFFLSNWLSLIESLISKL------------ 228

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  449 etlqnKDPKMSRVALESLYRLLWVYVIRIKcESNTVTQSRLMSIVSALFPKGSRSVVPRDTPLNIFVKIIQFIAQERLDF 528
Cdd:pfam14222  229 -----KDKTTRPVALQGLSRLLWVYLYRCT-ESLNTTTRKLESILKLLFPPGKKTWLPADPPLDPLVQIIRFIGFKHPDF 302

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  529 AMKEIIFDLLSVG--KSTKTFTINPERMNIGLRVFLVIADSLQQKDGEPPMPTTGVILPSGN--TLRVKKIFLNKTlTDE 604
Cdd:pfam14222  303 CFENIIFPLLNADlfNGLKLENLNPERMIIGIRAFLAILSDLEKGEQRPPFPQSFGTLPSPSssALRSKEENLSRP-VDT 381

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  605 EAKVIGMSVYYPQVRKALDSILRHLDKEVGRPM-------------CMTSVQMSNKEPED-MITGERKPKIDLFRTCIAA 670
Cdd:pfam14222  382 LALSEGIKDYYERFCKILGKILILCDNTFGGQAvldekfssptpktPISETFNFSRRPDDnAYDGQRQPFYELLHTAVQA 461

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  671 IPRLIPDGMSRTDLIELLARLTIHMDEELRALAFNTLQALMLdfPDWREDVLSGFVYFIV---------REVTDVHPTLL 741
Cdd:pfam14222  462 IPRCLPSSIPFNSLIELLCRGTVHVDPNIAESAAQALKRIAR--PSHAQQVITGFARFIFnfddrystmSDGGMLGPGHI 539

                          570
                   ....*....|....*
gi 1370486745  742 DNAVKMLVQLINQWK 756
Cdd:pfam14222  540 ESLLKLYVELLEIWI 554
MOR2-PAG1_mid pfam14228
Cell morphogenesis central region; This family is the conserved central region of proteins ...
 788-1553 1.68e-29

Cell morphogenesis central region; This family is the conserved central region of proteins that are involved in cell morphogenesis.


Pssm-ID: 433790 [Multi-domain]  Cd Length: 1113  Bit Score: 128.22  E-value: 1.68e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  788 SNVFHV--VEGFALVILCSSRPATRRLAVSVLREIRALFALLEIPKGDDELAIDVMDRLSPSILESFIHLTGADQTTLLY 865
Cdd:pfam14228    1 TNEFRPsgLDAVGLIFLSSVDVQIRHTALELLRCVRALYNDLRDMSSKERSDVSWKNNKEPIFIIDVFEENGDDIVQQCY 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  866 CPSSIDLQTLAEWNSSPISHQFDVISPShiwifahvtQGQDPWIISLSSFLKQENlpKHCSTAVSYAWMFAYTRLQLLSP 945
Cdd:pfam14228   81 WDSGRPYDMRRESDAIPPDLTLQSILES---------PDKGRWARCLSELVKYAA--ELCPSSVQEARLEVVQRLAQITP 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  946 qVDINSpinakKVNTTTSSDSYIGLWRNYLILCCSaatsssstsagsvrCsPPETlasTPDSGYSidskiigipSPSSLF 1025
Cdd:pfam14228  150 -VELGG-----KAHQSQDADNKLDQWLLYSMFACS--------------C-PPDD---VEDTKSH---------SAKELY 196

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1026 KHIVPMMRSESMEITESLVLGLGRTNPGAFRELIEELHPIIKEA---LERRPENMKRRRRRDILRVQLVRIFELLAD--- 1099
Cdd:pfam14228  197 HLIFPSLKSGSETHIHAATLALGHSHLEVCEPMFGELRSFLDEVateTESKPKWKSQKARREELRVHVANIYRMVAEnfw 276

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1100 AGVISHSASGGLdnetHFLNntLLEyvDLTRQLLEAENEKDSDtLKDIRCHFSALVANIIQNVpVHQRRSIFPQQSlRHS 1179
Cdd:pfam14228  277 PGMLIRKPVFRL----HVLK--FIE--DTVRYITTSPLENFQD-LQPLRFALASVLRSLAPEF-VKSKSERFDPRT-RKR 345

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1180 LFMLFSHWAGPFSIMFT---------PLDRYS------------------DRNMQINRHQYCALKAMSAVLCcGPVADNV 1232
Cdd:pfam14228  346 LFDLLASWCDDTGTVWSqdgvsdyrrEVERYKssqnsrskdsvdkisfdkEVNEQVEAIQWIAMNAMAALLY-GPCFDDN 424

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1233 GLSSDGYLYKWLDNILD------------------------------SLDKKVHQLGCEAVTL-------LLELNPDqsn 1275
Cdd:pfam14228  425 ARKMSGRVIAWINGLFLepaprapfgyspadprtpsyskfagegvrgLGGKDRHRGGPLRVHLakvalknLLQTNLD--- 501

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1276 LMYWAVDRCYTGSGRVAAGCFKAIANVFQNRDY-QCDTVMLLNLILFKAADSSRSIYEVAMQLLQILEPKmfRYAHKLEV 1354
Cdd:pfam14228  502 LFPACIDQCYSSDASIADGYFSVLAEVYMRQEIpRCDIQRLLSLILYKVVDPSRRIRDDALQMLETLSVR--EWAEDGEE 579

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1355 QRTDGVLSQLSPLPHLYSVSYYQLSEELARAYPELTLAIFSEISQRIQTA--HPAGRQVmLHYLLPWMNNIELVDLKplp 1432
Cdd:pfam14228  580 GTGRYRAAVVGNLPDSYQQFQYKLSAKLAKDHPELSELLCEEIMQRQLDAvdIIAQHQV-LTCMAPWIENLNFLKLW--- 655

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1433 tarrhdededDSlkdrelmvtsrrwlrgeGWgspqaTAMVLNNLMYMTAKYGDELAwSEVENVWTTLADGwPKNLKIILH 1512
Cdd:pfam14228  656 ----------ES-----------------GW-----SERLLKSLYYVTWRHGDQFP-DEIEKLWRTIASK-PRNISPVLD 701

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1370486745 1513 FLIS--ICGVNSEPS---------LLPYVKKVIVYLGRDKTMQLLEELVSEL 1553
Cdd:pfam14228  702 FLISkgIEDCDSNASaeitgafatYFSVAKRVSLYLARICPQQTIDHLVYEL 753
 
Name Accession Description Interval E-value
MOR2-PAG1_N pfam14222
Cell morphogenesis N-terminal; This family is the conserved N-terminal region of proteins that ...
 209-756 0e+00

Cell morphogenesis N-terminal; This family is the conserved N-terminal region of proteins that are involved in cell morphogenesis.


Pssm-ID: 464107  Cd Length: 554  Bit Score: 619.98  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  209 ERRDLAVDFIFCLVLVEVLKQIPVHPVPDPLVHEVLNLAFKHFKHKEGYSGTNTGNVHIIADLYAEVIGVLAQSKFQAVR 288
Cdd:pfam14222    1 ERKSLASIYILCRVLIEIVKQSPLDALTEELGDKLEEIVFGQLKTADPDQLSSSPNRSANWNLFAELLGVLSEIRFVSVS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  289 KKFVTELKELRQKEQSPHVVQSVISLIMGMKFFRVKMYPVEDFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILIPV 368
Cdd:pfam14222   81 DRFIAELEKLPKGLSSKDLEAKIELLIRGMRYLRIKVYPEEAFEESADFMQSLAKFFLNAHGQRVKHAYAEVLVELLLPV 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  369 AAAVKNEVNVPCLKNFVEMLYQTTFELSSRKKHSLALYPLITCLLCVSQKQFFLNNWHIFLQNCLSHLkmpsnnsirkqi 448
Cdd:pfam14222  161 AATATAEVNHPKWKEAVELLYPRAAKMASKPRHWNVAFPLVTTLLCVSPKEFFLSNWLSLIESLISKL------------ 228

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  449 etlqnKDPKMSRVALESLYRLLWVYVIRIKcESNTVTQSRLMSIVSALFPKGSRSVVPRDTPLNIFVKIIQFIAQERLDF 528
Cdd:pfam14222  229 -----KDKTTRPVALQGLSRLLWVYLYRCT-ESLNTTTRKLESILKLLFPPGKKTWLPADPPLDPLVQIIRFIGFKHPDF 302

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  529 AMKEIIFDLLSVG--KSTKTFTINPERMNIGLRVFLVIADSLQQKDGEPPMPTTGVILPSGN--TLRVKKIFLNKTlTDE 604
Cdd:pfam14222  303 CFENIIFPLLNADlfNGLKLENLNPERMIIGIRAFLAILSDLEKGEQRPPFPQSFGTLPSPSssALRSKEENLSRP-VDT 381

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  605 EAKVIGMSVYYPQVRKALDSILRHLDKEVGRPM-------------CMTSVQMSNKEPED-MITGERKPKIDLFRTCIAA 670
Cdd:pfam14222  382 LALSEGIKDYYERFCKILGKILILCDNTFGGQAvldekfssptpktPISETFNFSRRPDDnAYDGQRQPFYELLHTAVQA 461

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  671 IPRLIPDGMSRTDLIELLARLTIHMDEELRALAFNTLQALMLdfPDWREDVLSGFVYFIV---------REVTDVHPTLL 741
Cdd:pfam14222  462 IPRCLPSSIPFNSLIELLCRGTVHVDPNIAESAAQALKRIAR--PSHAQQVITGFARFIFnfddrystmSDGGMLGPGHI 539

                          570
                   ....*....|....*
gi 1370486745  742 DNAVKMLVQLINQWK 756
Cdd:pfam14222  540 ESLLKLYVELLEIWI 554
MOR2-PAG1_mid pfam14228
Cell morphogenesis central region; This family is the conserved central region of proteins ...
 788-1553 1.68e-29

Cell morphogenesis central region; This family is the conserved central region of proteins that are involved in cell morphogenesis.


Pssm-ID: 433790 [Multi-domain]  Cd Length: 1113  Bit Score: 128.22  E-value: 1.68e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  788 SNVFHV--VEGFALVILCSSRPATRRLAVSVLREIRALFALLEIPKGDDELAIDVMDRLSPSILESFIHLTGADQTTLLY 865
Cdd:pfam14228    1 TNEFRPsgLDAVGLIFLSSVDVQIRHTALELLRCVRALYNDLRDMSSKERSDVSWKNNKEPIFIIDVFEENGDDIVQQCY 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  866 CPSSIDLQTLAEWNSSPISHQFDVISPShiwifahvtQGQDPWIISLSSFLKQENlpKHCSTAVSYAWMFAYTRLQLLSP 945
Cdd:pfam14228   81 WDSGRPYDMRRESDAIPPDLTLQSILES---------PDKGRWARCLSELVKYAA--ELCPSSVQEARLEVVQRLAQITP 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745  946 qVDINSpinakKVNTTTSSDSYIGLWRNYLILCCSaatsssstsagsvrCsPPETlasTPDSGYSidskiigipSPSSLF 1025
Cdd:pfam14228  150 -VELGG-----KAHQSQDADNKLDQWLLYSMFACS--------------C-PPDD---VEDTKSH---------SAKELY 196

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1026 KHIVPMMRSESMEITESLVLGLGRTNPGAFRELIEELHPIIKEA---LERRPENMKRRRRRDILRVQLVRIFELLAD--- 1099
Cdd:pfam14228  197 HLIFPSLKSGSETHIHAATLALGHSHLEVCEPMFGELRSFLDEVateTESKPKWKSQKARREELRVHVANIYRMVAEnfw 276

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1100 AGVISHSASGGLdnetHFLNntLLEyvDLTRQLLEAENEKDSDtLKDIRCHFSALVANIIQNVpVHQRRSIFPQQSlRHS 1179
Cdd:pfam14228  277 PGMLIRKPVFRL----HVLK--FIE--DTVRYITTSPLENFQD-LQPLRFALASVLRSLAPEF-VKSKSERFDPRT-RKR 345

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1180 LFMLFSHWAGPFSIMFT---------PLDRYS------------------DRNMQINRHQYCALKAMSAVLCcGPVADNV 1232
Cdd:pfam14228  346 LFDLLASWCDDTGTVWSqdgvsdyrrEVERYKssqnsrskdsvdkisfdkEVNEQVEAIQWIAMNAMAALLY-GPCFDDN 424

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1233 GLSSDGYLYKWLDNILD------------------------------SLDKKVHQLGCEAVTL-------LLELNPDqsn 1275
Cdd:pfam14228  425 ARKMSGRVIAWINGLFLepaprapfgyspadprtpsyskfagegvrgLGGKDRHRGGPLRVHLakvalknLLQTNLD--- 501

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1276 LMYWAVDRCYTGSGRVAAGCFKAIANVFQNRDY-QCDTVMLLNLILFKAADSSRSIYEVAMQLLQILEPKmfRYAHKLEV 1354
Cdd:pfam14228  502 LFPACIDQCYSSDASIADGYFSVLAEVYMRQEIpRCDIQRLLSLILYKVVDPSRRIRDDALQMLETLSVR--EWAEDGEE 579

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1355 QRTDGVLSQLSPLPHLYSVSYYQLSEELARAYPELTLAIFSEISQRIQTA--HPAGRQVmLHYLLPWMNNIELVDLKplp 1432
Cdd:pfam14228  580 GTGRYRAAVVGNLPDSYQQFQYKLSAKLAKDHPELSELLCEEIMQRQLDAvdIIAQHQV-LTCMAPWIENLNFLKLW--- 655

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370486745 1433 tarrhdededDSlkdrelmvtsrrwlrgeGWgspqaTAMVLNNLMYMTAKYGDELAwSEVENVWTTLADGwPKNLKIILH 1512
Cdd:pfam14228  656 ----------ES-----------------GW-----SERLLKSLYYVTWRHGDQFP-DEIEKLWRTIASK-PRNISPVLD 701

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1370486745 1513 FLIS--ICGVNSEPS---------LLPYVKKVIVYLGRDKTMQLLEELVSEL 1553
Cdd:pfam14228  702 FLISkgIEDCDSNASaeitgafatYFSVAKRVSLYLARICPQQTIDHLVYEL 753
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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