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Conserved domains on  [gi|755494027|ref|XP_011246266|]
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thrombospondin type-1 domain-containing protein 7B isoform X1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1251-1304 1.11e-12

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


:

Pssm-ID: 465948  Cd Length: 52  Bit Score: 63.84  E-value: 1.11e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 755494027  1251 CQLSGWTTWTECSQTCGqGGRMSRTRFIIMPTQGEGRQCPtELTQQKPCPVTPC 1304
Cdd:pfam19028    1 CVVSEWSEWSECSVTCG-GGVQTRTRTVIVEPQNGGRPCP-ELLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 337-398 2.77e-12

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


:

Pssm-ID: 465948  Cd Length: 52  Bit Score: 62.68  E-value: 2.77e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 755494027   337 CETSEWSPWSPCSKTCrsgtlSPGVRSRSRNVKHIAIGGGQECPELLEKETCiaegeFLQPC 398
Cdd:pfam19028    1 CVVSEWSEWSECSVTC-----GGGVQTRTRTVIVEPQNGGRPCPELLERRPC-----NLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 180-229 3.09e-12

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


:

Pssm-ID: 465948  Cd Length: 52  Bit Score: 62.68  E-value: 3.09e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 755494027   180 CVVSEFSPWSTCPEGCGKKLQHRTRVAIAPPLYGGLQCPNLTESRACEAP 229
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGGVQTRTRTVIVEPQNGGRPCPELLERRPCNLP 50
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 602-660 8.87e-12

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


:

Pssm-ID: 465948  Cd Length: 52  Bit Score: 61.53  E-value: 8.87e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 755494027   602 CVVSEWTVWSSCSQSCsnknSDGKQTRSRSILALAGEGGKTCPssqELQEYRLCNDHSC 660
Cdd:pfam19028    1 CVVSEWSEWSECSVTC----GGGVQTRTRTVIVEPQNGGRPCP---ELLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 738-789 2.28e-10

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


:

Pssm-ID: 465948  Cd Length: 52  Bit Score: 57.29  E-value: 2.28e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 755494027   738 CLVTAFSEWTPCPRPCQPGnttiKQSRYRIIIQEAANGGQECPDTLfEEREC 789
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGG----VQTRTRTVIVEPQNGGRPCPELL-ERRPC 47
TSP1_spondin super family cl46269
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1374-1433 4.04e-09

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


The actual alignment was detected with superfamily member pfam19028:

Pssm-ID: 480609  Cd Length: 52  Bit Score: 53.82  E-value: 4.04e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755494027  1374 CHITPWSEWSKCELTCidgrsfeTTGRQSRSRTFIIQSFENQDSCPQQvLETRPCTGGKC 1433
Cdd:pfam19028    1 CVVSEWSEWSECSVTC-------GGGVQTRTRTVIVEPQNGGRPCPEL-LERRPCNLPPC 52
TSP1_spondin super family cl46269
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1131-1177 1.76e-07

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


The actual alignment was detected with superfamily member pfam19028:

Pssm-ID: 480609  Cd Length: 52  Bit Score: 49.20  E-value: 1.76e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 755494027  1131 CVMSEWGTWSRCPQSCDPhAMQRRTRHLLRPSLNS-RTCGEDSQVRPC 1177
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGG-GVQTRTRTVIVEPQNGgRPCPELLERRPC 47
TSP1_ADAMTS super family cl40597
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 1065-1125 1.38e-06

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


The actual alignment was detected with superfamily member pfam19030:

Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 46.68  E-value: 1.38e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755494027  1065 WVVEHWSPCkinnelrSPRCGRGTQSRRIRCVSTADreGGAVNRSLCNQDDAPQETQACSL 1125
Cdd:pfam19030    1 WVAGPWGEC-------SVTCGGGVQTRLVQCVQKGG--GSIVPDSECSAQKKPPETQSCNL 52
TSP1_ADAMTS super family cl40597
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 665-733 2.46e-05

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


The actual alignment was detected with superfamily member pfam19030:

Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 43.21  E-value: 2.46e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755494027   665 WETSAWGSCSentlvtalnvtigwngeATCGVGIQTRKVFCIKSHVGQVMT-KRCPESTRPETVRPCFLP 733
Cdd:pfam19030    1 WVAGPWGECS-----------------VTCGGGVQTRLVQCVQKGGGSIVPdSECSAQKKPPETQSCNLK 53
TSP1_ADAMTS super family cl40597
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 44-95 2.57e-04

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


The actual alignment was detected with superfamily member pfam19030:

Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 40.51  E-value: 2.57e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 755494027    44 WKTGPWGRCAGDCGpGGAQSRAVWCFH-IEGWTSPMSNCDESSQPPKERSCFR 95
Cdd:pfam19030    1 WVAGPWGECSVTCG-GGVQTRLVQCVQkGGGSIVPDSECSAQKKPPETQSCNL 52
TSP1_spondin super family cl46269
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 485-542 2.61e-04

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


The actual alignment was detected with superfamily member pfam19028:

Pssm-ID: 480609  Cd Length: 52  Bit Score: 40.34  E-value: 2.61e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 755494027   485 CIVSSWSTWGPCvfenchDPQGKKGFRMRQRHVLMESTGPMGRCPHLAESVPCEDPMC 542
Cdd:pfam19028    1 CVVSEWSEWSEC------SVTCGGGVQTRTRTVIVEPQNGGRPCPELLERRPCNLPPC 52
 
Name Accession Description Interval E-value
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1251-1304 1.11e-12

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 63.84  E-value: 1.11e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 755494027  1251 CQLSGWTTWTECSQTCGqGGRMSRTRFIIMPTQGEGRQCPtELTQQKPCPVTPC 1304
Cdd:pfam19028    1 CVVSEWSEWSECSVTCG-GGVQTRTRTVIVEPQNGGRPCP-ELLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 337-398 2.77e-12

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 62.68  E-value: 2.77e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 755494027   337 CETSEWSPWSPCSKTCrsgtlSPGVRSRSRNVKHIAIGGGQECPELLEKETCiaegeFLQPC 398
Cdd:pfam19028    1 CVVSEWSEWSECSVTC-----GGGVQTRTRTVIVEPQNGGRPCPELLERRPC-----NLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 180-229 3.09e-12

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 62.68  E-value: 3.09e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 755494027   180 CVVSEFSPWSTCPEGCGKKLQHRTRVAIAPPLYGGLQCPNLTESRACEAP 229
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGGVQTRTRTVIVEPQNGGRPCPELLERRPCNLP 50
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 602-660 8.87e-12

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 61.53  E-value: 8.87e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 755494027   602 CVVSEWTVWSSCSQSCsnknSDGKQTRSRSILALAGEGGKTCPssqELQEYRLCNDHSC 660
Cdd:pfam19028    1 CVVSEWSEWSECSVTC----GGGVQTRTRTVIVEPQNGGRPCP---ELLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 738-789 2.28e-10

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 57.29  E-value: 2.28e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 755494027   738 CLVTAFSEWTPCPRPCQPGnttiKQSRYRIIIQEAANGGQECPDTLfEEREC 789
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGG----VQTRTRTVIVEPQNGGRPCPELL-ERRPC 47
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1374-1433 4.04e-09

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 53.82  E-value: 4.04e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755494027  1374 CHITPWSEWSKCELTCidgrsfeTTGRQSRSRTFIIQSFENQDSCPQQvLETRPCTGGKC 1433
Cdd:pfam19028    1 CVVSEWSEWSECSVTC-------GGGVQTRTRTVIVEPQNGGRPCPEL-LERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1131-1177 1.76e-07

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 49.20  E-value: 1.76e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 755494027  1131 CVMSEWGTWSRCPQSCDPhAMQRRTRHLLRPSLNS-RTCGEDSQVRPC 1177
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGG-GVQTRTRTVIVEPQNGgRPCPELLERRPC 47
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 1065-1125 1.38e-06

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 46.68  E-value: 1.38e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755494027  1065 WVVEHWSPCkinnelrSPRCGRGTQSRRIRCVSTADreGGAVNRSLCNQDDAPQETQACSL 1125
Cdd:pfam19030    1 WVAGPWGEC-------SVTCGGGVQTRLVQCVQKGG--GSIVPDSECSAQKKPPETQSCNL 52
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 1254-1304 1.66e-05

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 43.73  E-value: 1.66e-05
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|..
gi 755494027   1254 SGWTTWTECSQTCGqGGRMSRTRFIIMPT-QGEGRQCPTELTQQKPCPVTPC 1304
Cdd:smart00209    2 SEWSEWSPCSVTCG-GGVQTRTRSCCSPPpQNGGGPCTGEDVETRACNEQPC 52
PTZ00441 PTZ00441
sporozoite surface protein 2 (SSP2); Provisional
 1205-1303 1.93e-05

sporozoite surface protein 2 (SSP2); Provisional


Pssm-ID: 240420 [Multi-domain]  Cd Length: 576  Bit Score: 49.19  E-value: 1.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755494027 1205 GQGVR---TRLLS-CVRSDGKS---VSMDHCEQRNLEKPQRMSIPCLVECVVNCQLsgWTTWTECSQTCGQGGRmSRTRf 1277
Cdd:PTZ00441  187 GQGINhqfNRLLAgCRPREGKCkfySDADWEEAKNLIKPFIAKVCTEVERTASCGP--WDEWTPCSVTCGKGTH-SRSR- 262

                          90       100
                  ....*....|....*....|....*....
gi 755494027 1278 iimPTQGEGrqCPTELTQQ---KPCPVTP 1303
Cdd:PTZ00441  263 ---PILHEG--CTTHMVEEceeEECPVEP 286
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 665-733 2.46e-05

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 43.21  E-value: 2.46e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755494027   665 WETSAWGSCSentlvtalnvtigwngeATCGVGIQTRKVFCIKSHVGQVMT-KRCPESTRPETVRPCFLP 733
Cdd:pfam19030    1 WVAGPWGECS-----------------VTCGGGVQTRLVQCVQKGGGSIVPdSECSAQKKPPETQSCNLK 53
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 340-399 1.13e-04

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 41.42  E-value: 1.13e-04
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 755494027    340 SEWSPWSPCSKTCRSgtlspGVRSRSRNVK-HIAIGGGQECPEL-LEKETCiaegeFLQPCP 399
Cdd:smart00209    2 SEWSEWSPCSVTCGG-----GVQTRTRSCCsPPPQNGGGPCTGEdVETRAC-----NEQPCP 53
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 44-95 2.57e-04

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 40.51  E-value: 2.57e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 755494027    44 WKTGPWGRCAGDCGpGGAQSRAVWCFH-IEGWTSPMSNCDESSQPPKERSCFR 95
Cdd:pfam19030    1 WVAGPWGECSVTCG-GGVQTRLVQCVQkGGGSIVPDSECSAQKKPPETQSCNL 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 485-542 2.61e-04

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 40.34  E-value: 2.61e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 755494027   485 CIVSSWSTWGPCvfenchDPQGKKGFRMRQRHVLMESTGPMGRCPHLAESVPCEDPMC 542
Cdd:pfam19028    1 CVVSEWSEWSEC------SVTCGGGVQTRTRTVIVEPQNGGRPCPELLERRPCNLPPC 52
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 604-660 7.70e-04

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 39.11  E-value: 7.70e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 755494027    604 VSEWTVWSSCSQSCSNknsdGKQTRSRS-ILALAGEGGKTCPSsqELQEYRLCNDHSC 660
Cdd:smart00209    1 WSEWSEWSPCSVTCGG----GVQTRTRScCSPPPQNGGGPCTG--EDVETRACNEQPC 52
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 182-233 2.14e-03

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 37.57  E-value: 2.14e-03
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....
gi 755494027    182 VSEFSPWSTCPEGCGKKLQHRTRVAI-APPLYGGLQCP-NLTESRACEAPVsCP 233
Cdd:smart00209    1 WSEWSEWSPCSVTCGGGVQTRTRSCCsPPPQNGGGPCTgEDVETRACNEQP-CP 53
PTZ00087 PTZ00087
thrombosponding-related protein; Provisional
 1134-1179 3.98e-03

thrombosponding-related protein; Provisional


Pssm-ID: 185438  Cd Length: 340  Bit Score: 41.47  E-value: 3.98e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 755494027 1134 SEWGTWSRCPQSCD-PHAMQRRTRHLLRPSLNsrtC--GEDSQVRPCLL 1179
Cdd:PTZ00087  234 TEWGEWSNCSMECDhPDNVQIRERKCAHPSGD---CfkGDLKETRPCQV 279
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 1377-1433 8.78e-03

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 36.03  E-value: 8.78e-03
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 755494027   1377 TPWSEWSKCELTCidgrsfeTTGRQSRSRTFI-IQSFENQDSCPQQVLETRPCTGGKC 1433
Cdd:smart00209    2 SEWSEWSPCSVTC-------GGGVQTRTRSCCsPPPQNGGGPCTGEDVETRACNEQPC 52
 
Name Accession Description Interval E-value
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1251-1304 1.11e-12

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 63.84  E-value: 1.11e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 755494027  1251 CQLSGWTTWTECSQTCGqGGRMSRTRFIIMPTQGEGRQCPtELTQQKPCPVTPC 1304
Cdd:pfam19028    1 CVVSEWSEWSECSVTCG-GGVQTRTRTVIVEPQNGGRPCP-ELLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 337-398 2.77e-12

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 62.68  E-value: 2.77e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 755494027   337 CETSEWSPWSPCSKTCrsgtlSPGVRSRSRNVKHIAIGGGQECPELLEKETCiaegeFLQPC 398
Cdd:pfam19028    1 CVVSEWSEWSECSVTC-----GGGVQTRTRTVIVEPQNGGRPCPELLERRPC-----NLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 180-229 3.09e-12

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 62.68  E-value: 3.09e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 755494027   180 CVVSEFSPWSTCPEGCGKKLQHRTRVAIAPPLYGGLQCPNLTESRACEAP 229
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGGVQTRTRTVIVEPQNGGRPCPELLERRPCNLP 50
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 602-660 8.87e-12

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 61.53  E-value: 8.87e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 755494027   602 CVVSEWTVWSSCSQSCsnknSDGKQTRSRSILALAGEGGKTCPssqELQEYRLCNDHSC 660
Cdd:pfam19028    1 CVVSEWSEWSECSVTC----GGGVQTRTRTVIVEPQNGGRPCP---ELLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 738-789 2.28e-10

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 57.29  E-value: 2.28e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 755494027   738 CLVTAFSEWTPCPRPCQPGnttiKQSRYRIIIQEAANGGQECPDTLfEEREC 789
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGG----VQTRTRTVIVEPQNGGRPCPELL-ERRPC 47
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1374-1433 4.04e-09

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 53.82  E-value: 4.04e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755494027  1374 CHITPWSEWSKCELTCidgrsfeTTGRQSRSRTFIIQSFENQDSCPQQvLETRPCTGGKC 1433
Cdd:pfam19028    1 CVVSEWSEWSECSVTC-------GGGVQTRTRTVIVEPQNGGRPCPEL-LERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1131-1177 1.76e-07

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 49.20  E-value: 1.76e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 755494027  1131 CVMSEWGTWSRCPQSCDPhAMQRRTRHLLRPSLNS-RTCGEDSQVRPC 1177
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGG-GVQTRTRTVIVEPQNGgRPCPELLERRPC 47
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 1065-1125 1.38e-06

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 46.68  E-value: 1.38e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755494027  1065 WVVEHWSPCkinnelrSPRCGRGTQSRRIRCVSTADreGGAVNRSLCNQDDAPQETQACSL 1125
Cdd:pfam19030    1 WVAGPWGEC-------SVTCGGGVQTRLVQCVQKGG--GSIVPDSECSAQKKPPETQSCNL 52
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 1254-1304 1.66e-05

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 43.73  E-value: 1.66e-05
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|..
gi 755494027   1254 SGWTTWTECSQTCGqGGRMSRTRFIIMPT-QGEGRQCPTELTQQKPCPVTPC 1304
Cdd:smart00209    2 SEWSEWSPCSVTCG-GGVQTRTRSCCSPPpQNGGGPCTGEDVETRACNEQPC 52
PTZ00441 PTZ00441
sporozoite surface protein 2 (SSP2); Provisional
 1205-1303 1.93e-05

sporozoite surface protein 2 (SSP2); Provisional


Pssm-ID: 240420 [Multi-domain]  Cd Length: 576  Bit Score: 49.19  E-value: 1.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755494027 1205 GQGVR---TRLLS-CVRSDGKS---VSMDHCEQRNLEKPQRMSIPCLVECVVNCQLsgWTTWTECSQTCGQGGRmSRTRf 1277
Cdd:PTZ00441  187 GQGINhqfNRLLAgCRPREGKCkfySDADWEEAKNLIKPFIAKVCTEVERTASCGP--WDEWTPCSVTCGKGTH-SRSR- 262

                          90       100
                  ....*....|....*....|....*....
gi 755494027 1278 iimPTQGEGrqCPTELTQQ---KPCPVTP 1303
Cdd:PTZ00441  263 ---PILHEG--CTTHMVEEceeEECPVEP 286
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 665-733 2.46e-05

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 43.21  E-value: 2.46e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755494027   665 WETSAWGSCSentlvtalnvtigwngeATCGVGIQTRKVFCIKSHVGQVMT-KRCPESTRPETVRPCFLP 733
Cdd:pfam19030    1 WVAGPWGECS-----------------VTCGGGVQTRLVQCVQKGGGSIVPdSECSAQKKPPETQSCNLK 53
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 340-399 1.13e-04

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 41.42  E-value: 1.13e-04
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 755494027    340 SEWSPWSPCSKTCRSgtlspGVRSRSRNVK-HIAIGGGQECPEL-LEKETCiaegeFLQPCP 399
Cdd:smart00209    2 SEWSEWSPCSVTCGG-----GVQTRTRSCCsPPPQNGGGPCTGEdVETRAC-----NEQPCP 53
TSP_1 pfam00090
Thrombospondin type 1 domain;
1254-1304 1.17e-04

Thrombospondin type 1 domain;


Pssm-ID: 459668 [Multi-domain]  Cd Length: 49  Bit Score: 41.25  E-value: 1.17e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 755494027  1254 SGWTTWTECSQTCGQGGRMsRTRFIIMPTQGeGRQCPTELTQQKPCPVTPC 1304
Cdd:pfam00090    1 SPWSPWSPCSVTCGKGIQV-RQRTCKSPFPG-GEPCTGDDIETQACKMDKC 49
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 44-95 2.57e-04

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 40.51  E-value: 2.57e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 755494027    44 WKTGPWGRCAGDCGpGGAQSRAVWCFH-IEGWTSPMSNCDESSQPPKERSCFR 95
Cdd:pfam19030    1 WVAGPWGECSVTCG-GGVQTRLVQCVQkGGGSIVPDSECSAQKKPPETQSCNL 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 485-542 2.61e-04

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 40.34  E-value: 2.61e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 755494027   485 CIVSSWSTWGPCvfenchDPQGKKGFRMRQRHVLMESTGPMGRCPHLAESVPCEDPMC 542
Cdd:pfam19028    1 CVVSEWSEWSEC------SVTCGGGVQTRTRTVIVEPQNGGRPCPELLERRPCNLPPC 52
TSP_1 pfam00090
Thrombospondin type 1 domain;
340-388 5.17e-04

Thrombospondin type 1 domain;


Pssm-ID: 459668 [Multi-domain]  Cd Length: 49  Bit Score: 39.32  E-value: 5.17e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 755494027   340 SEWSPWSPCSKTCrsgtlSPGVRSRSRNVKHIAIGGGQECPELLEKETC 388
Cdd:pfam00090    1 SPWSPWSPCSVTC-----GKGIQVRQRTCKSPFPGGEPCTGDDIETQAC 44
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 604-660 7.70e-04

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 39.11  E-value: 7.70e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 755494027    604 VSEWTVWSSCSQSCSNknsdGKQTRSRS-ILALAGEGGKTCPSsqELQEYRLCNDHSC 660
Cdd:smart00209    1 WSEWSEWSPCSVTCGG----GVQTRTRScCSPPPQNGGGPCTG--EDVETRACNEQPC 52
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 182-233 2.14e-03

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 37.57  E-value: 2.14e-03
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....
gi 755494027    182 VSEFSPWSTCPEGCGKKLQHRTRVAI-APPLYGGLQCP-NLTESRACEAPVsCP 233
Cdd:smart00209    1 WSEWSEWSPCSVTCGGGVQTRTRSCCsPPPQNGGGPCTgEDVETRACNEQP-CP 53
PTZ00087 PTZ00087
thrombosponding-related protein; Provisional
 1134-1179 3.98e-03

thrombosponding-related protein; Provisional


Pssm-ID: 185438  Cd Length: 340  Bit Score: 41.47  E-value: 3.98e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 755494027 1134 SEWGTWSRCPQSCD-PHAMQRRTRHLLRPSLNsrtC--GEDSQVRPCLL 1179
Cdd:PTZ00087  234 TEWGEWSNCSMECDhPDNVQIRERKCAHPSGD---CfkGDLKETRPCQV 279
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 1377-1433 8.78e-03

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 36.03  E-value: 8.78e-03
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 755494027   1377 TPWSEWSKCELTCidgrsfeTTGRQSRSRTFI-IQSFENQDSCPQQVLETRPCTGGKC 1433
Cdd:smart00209    2 SEWSEWSPCSVTC-------GGGVQTRTRSCCsPPPQNGGGPCTGEDVETRACNEQPC 52
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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